LOCUS       DAYYYC010000001       107374 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.001, whole genome shotgun sequence.
ACCESSION   DAYYYC010000001 DAYYYC010000000
VERSION     DAYYYC010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 107374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 107374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..107374
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.001"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..637
                     /locus_tag="ACHBV5_000001"
     CDS             <1..637
                     /locus_tag="ACHBV5_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFM9965885.1"
                     /translation="TSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSISLTLINFF
                     YSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQIVGVFLF
                     LNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGRVNTTIDS
                     IISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY"
     gene            675..1038
                     /locus_tag="ACHBV5_000002"
                     /pseudo
     CDS             675..1038
                     /locus_tag="ACHBV5_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032902.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
     gene            1062..1295
                     /locus_tag="ACHBV5_000003"
     CDS             1062..1295
                     /locus_tag="ACHBV5_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFM9965886.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            complement(1261..1392)
                     /locus_tag="ACHBV5_000004"
                     /pseudo
     CDS             complement(1261..1392)
                     /locus_tag="ACHBV5_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_152639374.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            1578..3527
                     /gene="mutL"
                     /locus_tag="ACHBV5_000005"
     CDS             1578..3527
                     /gene="mutL"
                     /locus_tag="ACHBV5_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFM9965887.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(3852..4319)
                     /gene="ribE"
                     /locus_tag="ACHBV5_000006"
     CDS             complement(3852..4319)
                     /gene="ribE"
                     /locus_tag="ACHBV5_000006"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HFM9965888.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIAVAWIPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(4320..5525)
                     /locus_tag="ACHBV5_000007"
     CDS             complement(4320..5525)
                     /locus_tag="ACHBV5_000007"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HFM9965889.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(5545..6180)
                     /gene="ribE"
                     /locus_tag="ACHBV5_000008"
     CDS             complement(5545..6180)
                     /gene="ribE"
                     /locus_tag="ACHBV5_000008"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HFM9965890.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(6165..7265)
                     /gene="ribD"
                     /locus_tag="ACHBV5_000009"
     CDS             complement(6165..7265)
                     /gene="ribD"
                     /locus_tag="ACHBV5_000009"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HFM9965891.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(7400..7514)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7671..8264
                     /gene="ruvA"
                     /locus_tag="ACHBV5_000010"
     CDS             7671..8264
                     /gene="ruvA"
                     /locus_tag="ACHBV5_000010"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFM9965892.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            8274..8837
                     /locus_tag="ACHBV5_000011"
     CDS             8274..8837
                     /locus_tag="ACHBV5_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFM9965893.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            8834..9511
                     /locus_tag="ACHBV5_000012"
     CDS             8834..9511
                     /locus_tag="ACHBV5_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFM9965894.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIATYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVDYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(9666..10697)
                     /locus_tag="ACHBV5_000013"
     CDS             complement(9666..10697)
                     /locus_tag="ACHBV5_000013"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HFM9965895.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKVLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEEPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDNNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(10952..11635)
                     /locus_tag="ACHBV5_000014"
     CDS             complement(10952..11635)
                     /locus_tag="ACHBV5_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFM9965896.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(11647..12591)
                     /locus_tag="ACHBV5_000015"
     CDS             complement(11647..12591)
                     /locus_tag="ACHBV5_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFM9965897.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            12723..15554
                     /gene="uvrA"
                     /locus_tag="ACHBV5_000016"
     CDS             12723..15554
                     /gene="uvrA"
                     /locus_tag="ACHBV5_000016"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFM9965898.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            15547..16608
                     /locus_tag="ACHBV5_000017"
     CDS             15547..16608
                     /locus_tag="ACHBV5_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFM9965899.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLFPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            16740..17138
                     /gene="spx"
                     /locus_tag="ACHBV5_000018"
     CDS             16740..17138
                     /gene="spx"
                     /locus_tag="ACHBV5_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HFM9965900.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            17204..17773
                     /locus_tag="ACHBV5_000019"
     CDS             17204..17773
                     /locus_tag="ACHBV5_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HFM9965901.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLVGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            17860..18126
                     /locus_tag="ACHBV5_000020"
     CDS             17860..18126
                     /locus_tag="ACHBV5_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFM9965902.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            18130..18549
                     /gene="ruvX"
                     /locus_tag="ACHBV5_000021"
     CDS             18130..18549
                     /gene="ruvX"
                     /locus_tag="ACHBV5_000021"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFM9965903.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            18565..18870
                     /locus_tag="ACHBV5_000022"
     CDS             18565..18870
                     /locus_tag="ACHBV5_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFM9965904.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            19283..20533
                     /locus_tag="ACHBV5_000023"
     CDS             19283..20533
                     /locus_tag="ACHBV5_000023"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFM9965905.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            20617..21087
                     /locus_tag="ACHBV5_000024"
     CDS             20617..21087
                     /locus_tag="ACHBV5_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HFM9965906.1"
                     /translation="MKLKRFTLSLASLASFSLLVACSQRAQQVQQPVAQQQVQQPAQQ
                     PAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTE
                     LESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            21233..22765
                     /gene="cls"
                     /locus_tag="ACHBV5_000025"
     CDS             21233..22765
                     /gene="cls"
                     /locus_tag="ACHBV5_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFM9965907.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGINLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            22843..22986
                     /locus_tag="ACHBV5_000026"
     CDS             22843..22986
                     /locus_tag="ACHBV5_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9965908.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            23023..24561
                     /locus_tag="ACHBV5_000027"
     CDS             23023..24561
                     /locus_tag="ACHBV5_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HFM9965909.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFEFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            24681..26888
                     /gene="nrdD"
                     /locus_tag="ACHBV5_000028"
     CDS             24681..26888
                     /gene="nrdD"
                     /locus_tag="ACHBV5_000028"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFM9965910.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            26900..27040
                     /locus_tag="ACHBV5_000029"
     CDS             26900..27040
                     /locus_tag="ACHBV5_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9965911.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            27084..27590
                     /locus_tag="ACHBV5_000030"
     CDS             27084..27590
                     /locus_tag="ACHBV5_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9965912.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNLASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            27583..28173
                     /gene="nrdG"
                     /locus_tag="ACHBV5_000031"
     CDS             27583..28173
                     /gene="nrdG"
                     /locus_tag="ACHBV5_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFM9965913.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            28170..28787
                     /locus_tag="ACHBV5_000032"
     CDS             28170..28787
                     /locus_tag="ACHBV5_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFM9965914.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            29053..29361
                     /gene="rpsJ"
                     /locus_tag="ACHBV5_000033"
     CDS             29053..29361
                     /gene="rpsJ"
                     /locus_tag="ACHBV5_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFM9965915.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            29578..30204
                     /gene="rplC"
                     /locus_tag="ACHBV5_000034"
     CDS             29578..30204
                     /gene="rplC"
                     /locus_tag="ACHBV5_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFM9965916.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            30229..30852
                     /gene="rplD"
                     /locus_tag="ACHBV5_000035"
     CDS             30229..30852
                     /gene="rplD"
                     /locus_tag="ACHBV5_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFM9965917.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            30852..31148
                     /locus_tag="ACHBV5_000036"
     CDS             30852..31148
                     /locus_tag="ACHBV5_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFM9965918.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            31166..31999
                     /gene="rplB"
                     /locus_tag="ACHBV5_000037"
     CDS             31166..31999
                     /gene="rplB"
                     /locus_tag="ACHBV5_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFM9965919.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            32103..32384
                     /gene="rpsS"
                     /locus_tag="ACHBV5_000038"
     CDS             32103..32384
                     /gene="rpsS"
                     /locus_tag="ACHBV5_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFM9965920.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            32396..32740
                     /gene="rplV"
                     /locus_tag="ACHBV5_000039"
     CDS             32396..32740
                     /gene="rplV"
                     /locus_tag="ACHBV5_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFM9965921.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            32753..33406
                     /gene="rpsC"
                     /locus_tag="ACHBV5_000040"
     CDS             32753..33406
                     /gene="rpsC"
                     /locus_tag="ACHBV5_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFM9965922.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            33410..33823
                     /gene="rplP"
                     /locus_tag="ACHBV5_000041"
     CDS             33410..33823
                     /gene="rplP"
                     /locus_tag="ACHBV5_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFM9965923.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            33833..34039
                     /gene="rpmC"
                     /locus_tag="ACHBV5_000042"
     CDS             33833..34039
                     /gene="rpmC"
                     /locus_tag="ACHBV5_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFM9965924.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            34064..34324
                     /gene="rpsQ"
                     /locus_tag="ACHBV5_000043"
     CDS             34064..34324
                     /gene="rpsQ"
                     /locus_tag="ACHBV5_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFM9965925.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            34350..34718
                     /gene="rplN"
                     /locus_tag="ACHBV5_000044"
     CDS             34350..34718
                     /gene="rplN"
                     /locus_tag="ACHBV5_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFM9965926.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            34796..35101
                     /gene="rplX"
                     /locus_tag="ACHBV5_000045"
     CDS             34796..35101
                     /gene="rplX"
                     /locus_tag="ACHBV5_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFM9965927.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            35125..35667
                     /gene="rplE"
                     /locus_tag="ACHBV5_000046"
     CDS             35125..35667
                     /gene="rplE"
                     /locus_tag="ACHBV5_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFM9965928.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            35685..35954
                     /gene="rpsN"
                     /locus_tag="ACHBV5_000047"
     CDS             35685..35954
                     /gene="rpsN"
                     /locus_tag="ACHBV5_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFM9965929.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            36239..36637
                     /gene="rpsH"
                     /locus_tag="ACHBV5_000048"
     CDS             36239..36637
                     /gene="rpsH"
                     /locus_tag="ACHBV5_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFM9965930.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            36829..37365
                     /gene="rplF"
                     /locus_tag="ACHBV5_000049"
     CDS             36829..37365
                     /gene="rplF"
                     /locus_tag="ACHBV5_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFM9965931.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            37449..37805
                     /gene="rplR"
                     /locus_tag="ACHBV5_000050"
     CDS             37449..37805
                     /gene="rplR"
                     /locus_tag="ACHBV5_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFM9965932.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            37823..38317
                     /gene="rpsE"
                     /locus_tag="ACHBV5_000051"
     CDS             37823..38317
                     /gene="rpsE"
                     /locus_tag="ACHBV5_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFM9965933.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            38331..38513
                     /gene="rpmD"
                     /locus_tag="ACHBV5_000052"
     CDS             38331..38513
                     /gene="rpmD"
                     /locus_tag="ACHBV5_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFM9965934.1"
                     /translation="MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            38658..39098
                     /gene="rplO"
                     /locus_tag="ACHBV5_000053"
     CDS             38658..39098
                     /gene="rplO"
                     /locus_tag="ACHBV5_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFM9965935.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            39111..40421
                     /gene="secY"
                     /locus_tag="ACHBV5_000054"
     CDS             39111..40421
                     /gene="secY"
                     /locus_tag="ACHBV5_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFM9965936.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            40572..41210
                     /locus_tag="ACHBV5_000055"
     CDS             40572..41210
                     /locus_tag="ACHBV5_000055"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFM9965937.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            41327..41545
                     /gene="infA"
                     /locus_tag="ACHBV5_000056"
     CDS             41327..41545
                     /gene="infA"
                     /locus_tag="ACHBV5_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFM9965938.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            41570..41686
                     /gene="rpmJ"
                     /locus_tag="ACHBV5_000057"
     CDS             41570..41686
                     /gene="rpmJ"
                     /locus_tag="ACHBV5_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFM9965939.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            41704..42069
                     /gene="rpsM"
                     /locus_tag="ACHBV5_000058"
     CDS             41704..42069
                     /gene="rpsM"
                     /locus_tag="ACHBV5_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFM9965940.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            42087..42470
                     /gene="rpsK"
                     /locus_tag="ACHBV5_000059"
     CDS             42087..42470
                     /gene="rpsK"
                     /locus_tag="ACHBV5_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFM9965941.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            42513..43448
                     /locus_tag="ACHBV5_000060"
     CDS             42513..43448
                     /locus_tag="ACHBV5_000060"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFM9965942.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            43460..43846
                     /gene="rplQ"
                     /locus_tag="ACHBV5_000061"
     CDS             43460..43846
                     /gene="rplQ"
                     /locus_tag="ACHBV5_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFM9965943.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            44111..44377
                     /locus_tag="ACHBV5_000062"
     CDS             44111..44377
                     /locus_tag="ACHBV5_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HFM9965944.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            44387..45724
                     /locus_tag="ACHBV5_000063"
     CDS             44387..45724
                     /locus_tag="ACHBV5_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HFM9965945.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            45968..46660
                     /locus_tag="ACHBV5_000064"
     CDS             45968..46660
                     /locus_tag="ACHBV5_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFM9965946.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(46763..48408)
                     /locus_tag="ACHBV5_000065"
                     /pseudo
     CDS             complement(46763..48408)
                     /locus_tag="ACHBV5_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(48398..49489)
                     /locus_tag="ACHBV5_000066"
                     /pseudo
     CDS             complement(48398..49489)
                     /locus_tag="ACHBV5_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(49502..50623)
                     /locus_tag="ACHBV5_000067"
                     /pseudo
     CDS             complement(49502..50623)
                     /locus_tag="ACHBV5_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(50840..51064)
                     /locus_tag="ACHBV5_000068"
                     /pseudo
     CDS             complement(50840..51064)
                     /locus_tag="ACHBV5_000068"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(51112..51888)
                     /locus_tag="ACHBV5_000069"
     CDS             complement(51112..51888)
                     /locus_tag="ACHBV5_000069"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HFM9965947.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            52010..52756
                     /locus_tag="ACHBV5_000070"
     CDS             52010..52756
                     /locus_tag="ACHBV5_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFM9965948.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            52769..53749
                     /locus_tag="ACHBV5_000071"
     CDS             52769..53749
                     /locus_tag="ACHBV5_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HFM9965949.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            53944..54264
                     /locus_tag="ACHBV5_000072"
     CDS             53944..54264
                     /locus_tag="ACHBV5_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFM9965950.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            54310..54618
                     /locus_tag="ACHBV5_000073"
     CDS             54310..54618
                     /locus_tag="ACHBV5_000073"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM9965951.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            54635..55933
                     /locus_tag="ACHBV5_000074"
     CDS             54635..55933
                     /locus_tag="ACHBV5_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFM9965952.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLAMSTMVYFPFFKIQDRLACQNEIKQS"
     gene            56084..58522
                     /locus_tag="ACHBV5_000075"
     CDS             56084..58522
                     /locus_tag="ACHBV5_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HFM9965953.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            58541..59209
                     /locus_tag="ACHBV5_000076"
     CDS             58541..59209
                     /locus_tag="ACHBV5_000076"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFM9965954.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            59227..60315
                     /locus_tag="ACHBV5_000077"
     CDS             59227..60315
                     /locus_tag="ACHBV5_000077"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HFM9965955.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            60797..63298
                     /gene="leuS"
                     /locus_tag="ACHBV5_000078"
     CDS             60797..63298
                     /gene="leuS"
                     /locus_tag="ACHBV5_000078"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFM9965956.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            63492..64187
                     /locus_tag="ACHBV5_000079"
     CDS             63492..64187
                     /locus_tag="ACHBV5_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFM9965957.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            64199..64615
                     /locus_tag="ACHBV5_000080"
     CDS             64199..64615
                     /locus_tag="ACHBV5_000080"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9965958.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(65430..65522)
                     /locus_tag="ACHBV5_000081"
     CDS             complement(65430..65522)
                     /locus_tag="ACHBV5_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFM9965959.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            65656..66654
                     /gene="ruvB"
                     /locus_tag="ACHBV5_000082"
     CDS             65656..66654
                     /gene="ruvB"
                     /locus_tag="ACHBV5_000082"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFM9965960.1"
                     /translation="MSRILDNEIMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            66635..67207
                     /locus_tag="ACHBV5_000083"
     CDS             66635..67207
                     /locus_tag="ACHBV5_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HFM9965961.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            67438..68196
                     /locus_tag="ACHBV5_000084"
     CDS             67438..68196
                     /locus_tag="ACHBV5_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFM9965962.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            68205..69008
                     /locus_tag="ACHBV5_000085"
     CDS             68205..69008
                     /locus_tag="ACHBV5_000085"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFM9965963.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            69030..70289
                     /gene="rseP"
                     /locus_tag="ACHBV5_000086"
     CDS             69030..70289
                     /gene="rseP"
                     /locus_tag="ACHBV5_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFM9965964.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            70302..72155
                     /locus_tag="ACHBV5_000087"
     CDS             70302..72155
                     /locus_tag="ACHBV5_000087"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFM9965965.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTSEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            72254..73633
                     /gene="bglA"
                     /locus_tag="ACHBV5_000088"
     CDS             72254..73633
                     /gene="bglA"
                     /locus_tag="ACHBV5_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFM9965966.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEHYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            73826..75634
                     /gene="glmS"
                     /locus_tag="ACHBV5_000089"
     CDS             73826..75634
                     /gene="glmS"
                     /locus_tag="ACHBV5_000089"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFM9965967.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKIEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLSLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGFDVDKPRNLAKSVTVE"
     gene            complement(75646..75849)
                     /locus_tag="ACHBV5_000090"
     CDS             complement(75646..75849)
                     /locus_tag="ACHBV5_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002668516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9965968.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTDEVSNHTYGKATLTWFEEI
                     FEEYNTNLEYKQPICSQEKGLDN"
     gene            75906..76955
                     /locus_tag="ACHBV5_000091"
     CDS             75906..76955
                     /locus_tag="ACHBV5_000091"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HFM9965969.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLALLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(77055..80891)
                     /gene="spuA"
                     /locus_tag="ACHBV5_000092"
     CDS             complement(77055..80891)
                     /gene="spuA"
                     /locus_tag="ACHBV5_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HFM9965970.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNKSDISSLGNANASLEKTEEKPATEPT
                     TPAASPADPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQ
                     GLWTWDDVEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNL
                     TGDKSVEKLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVK
                     NPSSAQWPDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFT
                     DLKNHSQIFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKH
                     SNITNHLGNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDE
                     TYSYDGKLGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTW
                     KQTLDSTNKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSNDAKIDDAHKVA
                     KAAFVDPAKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEA
                     FIEKLDYLKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSL
                     TGMYSSDPKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFM
                     DADGTPRTSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEA
                     YKAARALNPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGY
                     PNEGQPAFITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSI
                     KKDPSKAENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDK
                     VPNKSHLLRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKG
                     LIALRQSTDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVN
                     ADEKAREFNLGTAFAHLRNAEVLADENQAGPVGIANPKGLEWTEKGLKLNALTATVLR
                     VSQNGTSHESTAEEKPDSTPSKPEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQ
                     AEQPAQEAQASSVKEAVQNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGISL
                     LALLGLGFLLKNKKEN"
     gene            81308..81721
                     /gene="rpsL"
                     /locus_tag="ACHBV5_000093"
     CDS             81308..81721
                     /gene="rpsL"
                     /locus_tag="ACHBV5_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFM9965971.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            81741..82211
                     /gene="rpsG"
                     /locus_tag="ACHBV5_000094"
     CDS             81741..82211
                     /gene="rpsG"
                     /locus_tag="ACHBV5_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFM9965972.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            82636..84717
                     /gene="fusA"
                     /locus_tag="ACHBV5_000095"
     CDS             82636..84717
                     /gene="fusA"
                     /locus_tag="ACHBV5_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFM9965973.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            84821..89212
                     /locus_tag="ACHBV5_000096"
     CDS             84821..89212
                     /locus_tag="ACHBV5_000096"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFM9965974.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREVFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            89314..89577
                     /locus_tag="ACHBV5_000097"
     CDS             89314..89577
                     /locus_tag="ACHBV5_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HFM9965975.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            89570..89848
                     /locus_tag="ACHBV5_000098"
     CDS             89570..89848
                     /locus_tag="ACHBV5_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HFM9965976.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            89869..90021
                     /locus_tag="ACHBV5_000099"
     CDS             89869..90021
                     /locus_tag="ACHBV5_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9965977.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            90043..91284
                     /locus_tag="ACHBV5_000100"
     CDS             90043..91284
                     /locus_tag="ACHBV5_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFM9965978.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            91294..91524
                     /locus_tag="ACHBV5_000101"
     CDS             91294..91524
                     /locus_tag="ACHBV5_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFM9965979.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            91747..92469
                     /locus_tag="ACHBV5_000102"
     CDS             91747..92469
                     /locus_tag="ACHBV5_000102"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFM9965980.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            92686..94020
                     /gene="pepC"
                     /locus_tag="ACHBV5_000103"
     CDS             92686..94020
                     /gene="pepC"
                     /locus_tag="ACHBV5_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HFM9965981.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQTKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(94076..94987)
                     /locus_tag="ACHBV5_000104"
     CDS             complement(94076..94987)
                     /locus_tag="ACHBV5_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFM9965982.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(95011..95814)
                     /locus_tag="ACHBV5_000105"
     CDS             complement(95011..95814)
                     /locus_tag="ACHBV5_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFM9965983.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(95842..96831)
                     /locus_tag="ACHBV5_000106"
     CDS             complement(95842..96831)
                     /locus_tag="ACHBV5_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM9965984.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(97064..98083)
                     /gene="adhP"
                     /locus_tag="ACHBV5_000107"
     CDS             complement(97064..98083)
                     /gene="adhP"
                     /locus_tag="ACHBV5_000107"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HFM9965985.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSETMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(98422..99234)
                     /locus_tag="ACHBV5_000108"
     CDS             complement(98422..99234)
                     /locus_tag="ACHBV5_000108"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFM9965986.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            99424..100842
                     /locus_tag="ACHBV5_000109"
     CDS             99424..100842
                     /locus_tag="ACHBV5_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFM9965987.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTKVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            100895..101602
                     /locus_tag="ACHBV5_000110"
     CDS             100895..101602
                     /locus_tag="ACHBV5_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HFM9965988.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLMVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            101727..102671
                     /gene="folP"
                     /locus_tag="ACHBV5_000111"
     CDS             101727..102671
                     /gene="folP"
                     /locus_tag="ACHBV5_000111"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HFM9965989.1"
                     /translation="MSSKANHAKTAICGIINVTPDSFSDGGQFFALEQALQQARKLIA
                     EGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDTWKSQVAEAAL
                     AAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLIFPHFGFGQTF
                     TEKELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGLTKKENLLLLR
                     DLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTASAHVTSIAARQ
                     GVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            102673..103995
                     /locus_tag="ACHBV5_000112"
     CDS             102673..103995
                     /locus_tag="ACHBV5_000112"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFM9965990.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLESIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEEKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGCFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADH
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKARNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            103976..104530
                     /gene="folE"
                     /locus_tag="ACHBV5_000113"
     CDS             103976..104530
                     /gene="folE"
                     /locus_tag="ACHBV5_000113"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HFM9965991.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            104573..105385
                     /gene="folK"
                     /locus_tag="ACHBV5_000114"
     CDS             104573..105385
                     /gene="folK"
                     /locus_tag="ACHBV5_000114"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HFM9965992.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(105536..105853)
                     /locus_tag="ACHBV5_000115"
     CDS             complement(105536..105853)
                     /locus_tag="ACHBV5_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFM9965993.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            106210..106656
                     /gene="rplM"
                     /locus_tag="ACHBV5_000116"
     CDS             106210..106656
                     /gene="rplM"
                     /locus_tag="ACHBV5_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFM9965994.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISELI"
     gene            106675..107067
                     /gene="rpsI"
                     /locus_tag="ACHBV5_000117"
     CDS             106675..107067
                     /gene="rpsI"
                     /locus_tag="ACHBV5_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFM9965995.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
BASE COUNT        31934 a        19894 c        23868 g        31678 t
ORIGIN      
        1 aactagcaat gcgaatatag aaaacttctc tttcaaatat tacaagagag aagtgttgca
       61 aggtacaaag tttattttaa ataataaatt attatttaaa accagtattt ctttaacgct
      121 tataaacttt ttttattcat ttcagacagt agttgtaccg attttttcta ttcgatattt
      181 tgatggtccg attttttatg gtattttttt aactattgct ggtttgggtg gtatattggg
      241 aaatatgcta gcgccaatcg taataaaata tttaaaatcg aatcaaattg ttggtgtatt
      301 tctttttttg aacggctcaa gttggttagt agcaattgtt ataaaagact atactttatc
      361 acttatttta tttttcgttt gttttatgtc taaaggagtc ttcaatatta tttttaattc
      421 gttgtaccaa caaatacctc cacatcaact tcttggtagg gtaaatacta ccattgattc
      481 tattatttct tttggaatgc caattggtag tttagttgca ggaacgctta ttgatttgaa
      541 tattgaatta gtgttaattg ctattagcat accttatttt ttgttttctt atatttttta
      601 tacggataat ggattgaaag aatttagtat atattagaaa tgtttatgtt cattcaaaag
      661 cataatgact ataactgaaa aagaaaagtg atatctttaa ggttgttctt cttggtggtg
      721 agattcgtga gacaacccaa gcttttgtcg gaaagattac caatgctttg atggatagga
      781 tgtactttag caagatgttt ttagtggtaa cggtatcgtg gatggacgtg taataacctc
      841 ttctttcgag gagtatttta ctaaaaaact agccttggag cgttccccag aaacggactt
      901 actcattgac tcttcaaaga tttggggaga agattttgct tcatctgttc cttgaaaaaa
      961 gtcacagcag tcatcacaga cgatagtact gaacaaaact atgaagagtt agaaatttat
     1021 acgcaggtga ttgtataaag gatctggaaa tagataagaa gttgattagt attgacctag
     1081 gtggtacaaa tattaagatt actgttcttt caaatgacgg tgagattgaa actttgtgga
     1141 gtattacaac agatacaagt gagaaaggtt ctcaaattat atcggacatc atcagttcta
     1201 ttaaaaataa attgaccgaa cggaatattc ctgatagcga ccttcttgga atcggtatgg
     1261 gaagttgctc atcatacttt ccttgtaaat cataggggct ataaactctc cgtctacttg
     1321 tcctgcaaca attgaagtct gctcaaaacg ccgtccgcta atcttttcat agactttctc
     1381 ccttttagga gcctagcttt ctagtttgtt ctttgatttt tattgagtat accactattt
     1441 tactccctct ggcaagggac tttgtctatg tggagggatt gggctcctat gtggtggagc
     1501 ttttctgttc tttctgaaat atggtataat agcactaatc aatttctagg aaaatagata
     1561 cagaaagggg ctgaaagatg tctcatatta ttgaattgcc agagatgctg gcaaaccaaa
     1621 tcgcggctgg agaggtcatt gaacgtcctg ccagtgtggt caaagagttg gtagaaaatg
     1681 ccattgacgc gggctctagt cagattatca ttgagattga ggaagctggt ctcaagaagg
     1741 ttcaaatcac ggataacggt catggaattg cccacgatga ggtggagttg gccctgcgtc
     1801 gccatgcgac cagtaagata aaaaatcaag cagatctctt tcggattcgg acgcttggtt
     1861 ttcgtggtga agccttgcct tctattgcgt ctgttagtgt cttgactctg ttaacggcgg
     1921 tggatggtgc tagtcatgga accaagttag tcgcgcgtgg gggtgaagtt gaggaagtca
     1981 tcccagcgac tagtcctgtg ggaaccaagg tttgtgtgga ggatctcttt ttcaacacgc
     2041 ctgcccgtct caagtatatg aagagccagc aagcggagtt gtctcatatc attgatattg
     2101 tcaaccgtct gggcttggcc catcctgaga tttcttttag cttgattagt gatggcaagg
     2161 aaatgacgcg gacagcaggg actggtcaac tgcgccaagc aatcgcagga atttacggtt
     2221 tggtcagtgc caagaagatg attgaaattg agaactctga cctagatttc gaaatttcag
     2281 gttttgtgtc cttgcctgag ttgactcggg ctaaccgcaa ttatatcagc ctcttcatca
     2341 atggccgtta tattaagaac ttcctgctca atcgtgctat tttggatggt tttggaagca
     2401 agcttatggt tggacgtttt ccactggctg tcattcacat ccatatcgac ccttatctag
     2461 cggatgtcaa tgtgcatcca actaagcaag aggtgcggat ttccaaggaa aaagaactga
     2521 tgactctggt ttcagaagct attgcaaata gtctcaagga acaaaccttg attccagatg
     2581 ccttggaaaa tcttgccaaa tcgaccgtgc gcaatcgtga gaaggtggag caaactattc
     2641 tcccactcaa agaaaatacg ctctactatg agaaaactga gccgtcaaga cctagtcaaa
     2701 ctgaagtagc tgattatcag gtagaattga ctgatgaagg gcaggatttg accctgtttg
     2761 ccaaggaaac cttggaccga ttgaccaagc cagcaaaact gcattttgca gagagaaagc
     2821 ctgctaacta cgaccagcta gaccatccag agttagatct tgctagcatc gataaggctt
     2881 atgacaaact ggagcgagaa gaagcatcca gcttcccaga gttggagttt ttcggacaaa
     2941 tgcacgggac ttatctcttt gcccaagggc gagatggact ttacatcata gatcagcacg
     3001 ctgctcagga acgggtcaag tacgaggagt accgtgaaag cattggcaat gttgaccaga
     3061 gccagcagca actcctagtg ccctatatct ttgaatttcc tgcggatgat gccctgcgtc
     3121 tcaaggaaag aatgcctctc ttagaggaag tgggcgtctt tctagcagag tacggagaaa
     3181 atcaatttat tctacgtgaa catcctattt ggatggcaga agaagagatt gaatcaggca
     3241 tctatgagat gtgcgacatg ctccttttga ccaaggaagt ttctatcaag aaataccgag
     3301 cagagctggc tatcatgatg tcttgcaagc gatctatcaa ggccaatcat cgtattgatg
     3361 atcattcagc tagacaactc ctctatcagc tttctcaatg tgacaatccc tataactgtc
     3421 ctcacggacg tcctgttttg gtgcatttta ccaagtcgga tatggaaaag atgttccgac
     3481 gtattcagga aaatcacacc agtctccgtg agttggggaa atattaaaag tataaaaaag
     3541 tctgggaaaa attttcaaaa tcagaaaaac gcataaaatc aggtgttcaa aaaccttgat
     3601 tttatgcgtt ttatcataga aatatttact tcattttttc ctaattcttt tcgaaactct
     3661 ttttaaacga cgtcagtttt atcagtaatc tcaaaacagt gttttgagct aattttgcca
     3721 gttttgtctg taacatcgaa gttgtgtttt accactctgc ggctggtttc ctagtttgct
     3781 ctatgatttt cacagagtat taaattgcga ttttgccaag tttctttatt cgtctaaaag
     3841 tagagtctgt tctatgcgtc taatgtacga attaggttga ccatttcaat agctccttgt
     3901 gcacactcag aacccttatt tcctgcttta gtgccagctc gttctatggc ttgttcaatt
     3961 gtatctgtcg ttagcacacc aaacataaca ggaatttcgc tatttaaact gatttgggcg
     4021 attcccttag atacctcgct acatacataa tcataatgac ttgtattccc tctaatgaca
     4081 gctcccaagc agataattgc atcatatttt ttactttttg ccatttttga tgcaatcagt
     4141 ggtatttcaa aagctcctgg aatccaggct accgctatat ctttctcgtt tacattctct
     4201 cttttgagat tatctagtgc tccagataat aattttgaag ttataaattc attaaatctc
     4261 gctacaacaa tacctatttt aatattgttt gctactaaat taccttcata agtgttcatt
     4321 tatttttcct ccatatttaa aatgtgaccc attcgatttt tctttgtttc taaataaaaa
     4381 ctatcgtaag gattggcttc tatttcgatt gatattctac tggaaatggt aattccatat
     4441 ttttctaact gttcaacctt gtcaggatta tttgtcagta aatgaagtga ctgaagtccc
     4501 agatctttaa gcatttgtgc tccaatatga tattctctta aatcaccttc aaagcctaat
     4561 gcaagattgg catcaagcgt atccatgcct tgatcttgta aatgataggc ttttaattta
     4621 ttgataagtc caattcctcg tccctcctgt cgcaagtaaa gtaagacacc cgaaccattc
     4681 tcaacaatca ttttcatagc tttatcgaat tgctgtccac aatcgcaacg taaagagcct
     4741 aaaacatccc ctgttaaaca ttcggagtgg acccgacata atacattggc ttcatcctct
     4801 atgtttccca taataagagc aagatgatgt tccccattta gtttatctat atagctaatt
     4861 gctttgaaat taccgtatct agtaggcata ttgacagttg aaactcgttc taccagctga
     4921 tcatatactt ttctatattc ttgtaattct ttgatggtaa ttagtggaat gttgtgtttc
     4981 ttcgagaact gaattaaatc atctgttctc atcattttgc catcatgatt cattatttca
     5041 caacataggc cacactcttt tagtccagct aattttaata aatcaacagt tgcttctgtg
     5101 tgtccatttc tttctagaac accacctttt tttgcaatta aaggaaacat gtgtcctggc
     5161 ctgcgaaaat cagagggtgt tatatcttca gctacacaca tacgtgcggt cagtcctctt
     5221 tcctcggcag aaatacctgt ggtcgtttct ttataatcaa ttgaaactgt aaaagcagtc
     5281 ttatgattat ctgtattgtt ttcaaccata ggtgaaagca ttaattgatt agctaaactt
     5341 tcgctcatag gcatacaaat taatcctttg gcataagtag ccataaaatt aacattttct
     5401 gttgtagctg cttgtgcaga acaaattaag tctccttcat tttctctatc cttgtcgtct
     5461 ataacaagaa caagtcgtcc cttctgcaat gcttctaatg cttcttgtat ttttcgatat
     5521 tccattgact gattatcctt tctgctaaaa tccattttga tataatagtt ccttagatat
     5581 ttctgatttt ggagagttat ccatcagttt ttgcacatat ttacctaaga tatcattttc
     5641 aagatttact gtactcccga cttgtttact cttaagaatg gtttgttcca aggtatgagg
     5701 gataacagat actgaaaagt ttactttgga gactttagcg acagtcagac taatgccgtc
     5761 aattgtaata gatccttttt caactattaa atctaaaatt tctttttgtg tgttgatttg
     5821 ataccataca gcattatcat ctttttttat tgacgagatt tttcctgtac catcaatgtg
     5881 tcctgtaacg acgtgacccc caagtcgacc gttgacagat aaggctcttt ctagattcac
     5941 ctcacttcca tgttttaata gagtaagagc tgttcgactc catgtttcat tcattacatc
     6001 aactgtaaag gattgatggt tgaaatgagt aactgtaaga cagataccat ttactgctat
     6061 actatcgcct aaatggatat ccgttaatat ttttgaggct ttaattgata gtttacaatt
     6121 acgagagtct ttctgtattc tttcaacttt tccgatttct tcaattattc ctgtgaacat
     6181 ggataaatca cttcactttc tatgagatag tcatttccta tttgagaaaa agcataaggt
     6241 ttcaatctaa tagcgtcatt tggcaaagaa atgccttcac ctccgacagg aaacttggca
     6301 ctgcctccaa aaatttttgg tgcaatatat attttcagct catcaacaat ttgttgttcc
     6361 aaagcactcc aattcattag actgccccct tctagaacta ggctatcaat ctgcatgttt
     6421 cctagatgtt gcattaaact cgataagtct atatgattgc cttttttctt tatggaaagt
     6481 atttcacagc catgattttg atatagcttc attttatttt tgtcttcaga ggaagtggca
     6541 atgtaagttt taatatcatt tgctgttttt acgattttag aggtaagagg agttcgtaaa
     6601 tgtgtatcgc atatgatacg gataggattt ttcccttcct ccaatctaca tgtcagcaaa
     6661 ggatcgtctt gaataacagt attgactccc accataattg cactaacata gtgtcgtaac
     6721 tgatgcacat gctttcttgc ttcttcttca gtaatccatt tggattgatt tgttttagtg
     6781 gctatttttc catccattga cattgcatat ttcataaaaa catagggtac atgctgggta
     6841 atatactttc taaaactttt tattaagtta agacactcat tttctaaaat tccaacagta
     6901 acttgaagat tattttcctc aagtatcttt actccttttc cagatacaat aggattacag
     6961 tctaggcttc caatgactac tcttgtaata ccactatcga ttatagcatc tatacaggga
     7021 ggtgttttcc cgaagtgaca acagggttca agtgttacat aaagcgtcgc tccgacaggg
     7081 gattctctac agtttttaag agcatttctc tcagcatgtg ggccaccaaa aaactcatga
     7141 taaccttgtc cgatgatgtg attatctttt acaataactg cgccgaccat aggattggga
     7201 ttgacgtaac cagccccttt ttgtgccagt tttattgcta atttcatata ttttgaatcg
     7261 ctcatctcac tacctccaaa aaaaatatac cttgaatagg ggactactca aggcatacaa
     7321 aagaaaactt atgcgattaa caaaaatact ctgaaatgac aagtaatcat ttcagagcac
     7381 gcaaaaagca caaatatact tttatcttct ttcatccaga ctatactgtc ggctttggaa
     7441 tttcaccaaa tcatgccttt cggctcgtgg gctataccac cggtagggaa ttacaccctg
     7501 ccctgaagat agttattcaa ttacagatga ttatagtact taattttgaa tatgtcaaca
     7561 gataaatacc gattgttttt gatatactgt atttgtgata atcgattctc gctcctcgga
     7621 taaagaaaat atgatatact agataaacga aataagagag aaggaatact atgtacgcat
     7681 atttaaaagg aatcattacc aaaattactg ccaaatacat tgttcttgaa accaatggta
     7741 ttggttatat cctgcatgtg gccaatcctt atgcctattc aggtcaggtt aatcaggagg
     7801 ctcagattta tgtgcatcag gttgtgcgtg aggacgccca tttgctttat ggatttcgct
     7861 cagaggatga gaaaaagctc tttcttagtc tgatttcggt ctctgggatt ggtcctgtat
     7921 cagctcttgc tattatcgct gctgatgaca atgctggctt ggttcaagcc attgaaacca
     7981 agaacatcac ctacttgacc aagttcccta aaattggcaa gaaaacagcc cagcagatgg
     8041 tgctggactt ggaaggcaag gtagtagttg caggagatgg ccttcctgcc aaggtcgcag
     8101 tgcaagcaag tgctgaaaac caagaattgg aagaagctat ggaagccatg ttggctctgg
     8161 gctacaaggc aacagagctc aagaaaatca agaaattctt tgaaggaacg acagatacag
     8221 ctgagaacta tatcaagtcg gcccttaaaa tgttggtcaa ataggagcag agaatgacaa
     8281 aacgttgttc gtgggtcaag atgaccaacc cgctctacat cgcctatcat gatgaggagt
     8341 ggggtcagcc cctccatgat gaccaagcat tgtttgagtt gttgtgtatg gaaacctatc
     8401 aggcaggcct gtcttgggaa acggtactca acaaacgcca agctttccga gaagcctttc
     8461 atagctatca aattcactca gtcgcagaga tgactgacac tgaattggaa gccatgctgg
     8521 agaatccagc tatcattcga aatagagcca agatttttgc tacacgcgct aacgcccaag
     8581 cctttctaca gttacaggca gagtacggct cttttgatgc ctatctttgg tcttttgttg
     8641 aggggaaaac tgtcgttaac gatgttcctg attatcgcca agccccagct aaaacaccct
     8701 tatctgagaa attagccaaa gatctcaaaa aacgaggctt caagttcaca ggcccagtcg
     8761 ccgtattgtc ttttctacag gctgcagggc tagttgatga ccacgagaat gattgtgagt
     8821 ggaaaggtct taaatgatgt ctaacaaaaa taagggaatt ctgatttttg cgattctcta
     8881 tacagtcctc tttgtgtttg atggcgttaa attgctggct tctttaatgc catctgccat
     8941 tgcaacttat cttgtttatg tagttttagc tttatatggc tccttcttgt tcaaggatag
     9001 attgatccaa caatggaagg agattagaaa gactaaaaga aaattcttct ttggagtctt
     9061 aacaggatgg ctctttctca ttctgatgac tgttgtcttt gaatttgtat cagagatgtt
     9121 gaagcagttt gtgggactag atggacaagg tctaaatcag tctaatattc aaagtacctt
     9181 tcaagaacaa ccactactga tagctgtttt tgcttgtgtc attggacctc tggtagaaga
     9241 attatttttc cgtcaggtct tattgcatta cttgcaggaa cggttgccag gtttactaag
     9301 cattattctg gtaggacttg tttttgctct gactcatatg cacagtttgg ctctatcaga
     9361 gtggattggt gcagttgatt acttaggtgg aggccttgcc ttttctatta tttatgtgaa
     9421 agaaaaagag aatatctact atcccctact tgttcacatg ttaagcaaca gcctctcctt
     9481 aatcatttta gctatcagta tagtaaaatg aaataagaac aggacaaatc aatcaggaca
     9541 gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt actattctag tttcaataca
     9601 ctgtaacatg tgatgaaaat gccagtaatg ataccgagaa aaaagctgag aaacttttcc
     9661 cagctttatt tgttatagtc aaagcgaatg acttgttcct gtgcatctac atgagcatgg
     9721 accccaaagg gtacaattgc tcttggagtt gcgtggccga cattcagatt atagacaatc
     9781 gggatattgt tgtcaatgat atccaatagt gcctctttat agtcgtcatg gaaagtttca
     9841 tccataggtt ttccgaccaa gagtccattg atgaccgcga atatgccagt gtcctttaaa
     9901 gttagcaaca tctttttgaa gtcttctggc ttaggctctt cttcgcttgt ttcgagcaag
     9961 aggattttcc cttcccagtc tgacaagtca gggaaaagtt tgtatttttg gcagagttcc
    10021 gtgctatctg cgtatcgaga gttgtcaaag atatcgtaga gggattcgag gcaaccaccg
    10081 aggattttcc cctcgaactg agcacttcct tgcaacaagt caaaacctgt atttgtatga
    10141 ctgacacgag gtgttcccag ggccgtggga ctaaaatcag ttcgttcctc ataccaaacg
    10201 tcactagggc ggatttctga aattcttccc gtctcaatca attctttaaa gtagtgaagg
    10261 ctataggcta gcatttcttt gtctaattca caaatgtctg ctaaaaagga ttgaccataa
    10321 aaagtcttga ttcctaattt atgcaacatg aggtggttca tggttgtatc cgagaagcca
    10381 agaaaaattt tttgtttgat aaccttttgg agttggtcat tttcaaaaag ataaggtagc
    10441 aagcgatagg tatcgtctcc acctatggca cataggatca tgtcgatgct atcatcagaa
    10501 aaggcatgaa tcaaatcctc tgcacgagct tcaggatggt ccttgataaa gtctaatcct
    10561 tttaacgaat ggggcaaaaa gatgggattg agtcccagaa ccttgagacg ttggataccc
    10621 aagtccactt cgtgtttgac aaaatcctct ccgataatgc cactagataa actaacaata
    10681 ccaatagtag aaaccatatc tcatcctcct agaaatagat tgagcctatt ttatcacaaa
    10741 atataagaga aagctatgtg ggatttcaga agaatacttt taatactctt cgaaaatctc
    10801 ttcaaaccac gtcagtttta tctgcaacct caaagctgtg ctttgagcaa cctgcagcta
    10861 gcttcctagt ttgctctttg attttcattg agtataactc aaaaaagtaa gtgaaaaagc
    10921 aaccgcacct gcagttgctt ttatcgtttt cttattcttg atagcgtgtt ggtcctgcac
    10981 ttgcactacg gatattcaag cgtttcttga gatagaagcg aagggctagg agagctgctc
    11041 caataatagc tagtggcaat ggatccagta ctgggttaag gctagctggt aggaagcttg
    11101 ttgcaaagaa gacaagcaac caaaggaaca tagaagctag gataactagt acagatttcc
    11161 agaaaggtgg acgttgactg cgatccatat ctggtccata gtattggtaa acaaagtagt
    11221 acatcaagta gaaggcaaat ccaccaacca gtccaactaa tagaagagta atcaatccat
    11281 agccgaaagc ttgatctgcc gcaaagaagg ttgtgagggc gctgacaagg gcaaagaggc
    11341 tagtgatgaa aagagctgag tccataatca tcagttttgg gtcatcattt tcttttggat
    11401 gctctttttc gtactgctct ttgacagtga agctatgagc ccaatgagtt ggtgcgccgt
    11461 atagggaacg ggcagttgta cctttagatt gctcctcaag gatttgggga atgacttcct
    11521 caaaaatagt ctggatttca gcgtctgttt tcccatcttt gatgaattgt tgggtagcaa
    11581 tgtggacaaa ctcttggttt ttcttagtta atttttgtag atcaatttga gacataggaa
    11641 ctcctcttag aaccattttt tatggatgag atagagagtg agcgagacac tcatagcaaa
    11701 ggcgataaag acgattaacc agaaggcatt tggctctccg tttaggggaa tttcattatc
    11761 cttaaagttc atcccgtagg cagaaaagac catggttggg atggacatga cgatggtcac
    11821 aagggccaag gttttcatga tgttgttctg gttgttagaa atgatagagg caaaggtctc
    11881 tgtcatagaa tgcaagacgt ttccataaat atctgccatc tcgatggcct gttgggtttc
    11941 aatcagggtg tcttcaagca ggtcttcgtc ctcaaggtat ttcttgatat tgctggttga
    12001 actggtcaat ttcttaatca cgcgctcatt tgttttgagg gaggccttga aatagacgat
    12061 agttttttcc aattccatga gctcaatcaa ttcttcatta cgagttgatt gatgcagttg
    12121 actttcgatt tgttcactct tgcggtcgat tgaacgaagg gctgttaggt aaagctctgc
    12181 attgcgataa agaatttgaa agataaaacg tgaacgcatg aaggtataga aattacgcaa
    12241 tcgacggttg ataaagacat caaggacagg tagtggttcc aaacacgtag tgataatggt
    12301 ttcctcagtg atgataatac caagcgggat ggttacgtag taggtgcggt tatttctttc
    12361 ctccgtgacc ggcacgtcta cgataatcag ggtatactcg tcttcaatgg taatacgaga
    12421 catttcttcc gcatcgagcg gtgctcgaag gtcggcaata tcaatatcga aggtgttggc
    12481 gatttcgagt gattcatttt gagtcggatt gacgagattg atccaagtac ccggttcaag
    12541 cgtatcgatc tctttaaatt cagttgttgt agagagaaaa acttgtttca tatcccttat
    12601 cctttctcat ttttcagatt ttttcacact gtactattat actacaaaat cggccttttg
    12661 ggtaatagaa tctcactttt tttggtataa tggtaagcaa taatggacta gaaagaacaa
    12721 agatgcaaga taaaattgtc attcatgggg cgcgtgccca taatttaaaa aatattgatg
    12781 tggagattcc gcgagacaag ttggttgtcg tgactggctt gtcaggttca gggaagtcca
    12841 gtctggcttt tgatactctc tatgcggagg gacaacgtcg ctatgtagag agtttgtctg
    12901 cctacgctcg tcagttcttg ggaaatatgg aaaaaccaga tgtagatgcc attgatggtc
    12961 tcagcccagc tatttccatc gaccagaaaa cgactagtaa aaatcctcgc tcgacggtgg
    13021 gaacgacgac tgaaatcaat gactatctgc gtctcctcta cgcacgtgtg gggacgcctt
    13081 actgtatcaa cggacatgga gctatcaatg cttcttctgt ggagcaaatc gttgataagg
    13141 ttttggagtt acctgaacgc cagcgcttgc agatcttggc tcctgtcatc cgcaagaaaa
    13201 aaggccaaca taagagtgtt atcgagaagg ttcagaaaga cgggtatgtt cgtgttcgtg
    13261 tggatgggga agtctatgat gtgaccgaag tgccagagtt gtctaagagc aagcaacaca
    13321 atatcgatgt cgtggttgac cgtattgtta tcaaggaggg cattcgtagc cgtctctttg
    13381 attccattga agctgccctt cgtatcgcag aaggttatgt gattatcgac accatggacg
    13441 actctgagtt gttgttctct gagcattatg cctgtccagt ttgtggattt actgtcccag
    13501 agttagaacc tcgtctcttc tctttcaatg ctccctttgg ctcttgtagt gagtgtgacg
    13561 gcttggggat caagctggag gtagatactg atttggtagt gccagatgcc agcaaaacct
    13621 tacgtgaggg agcgctagca ccttggaatc ctatctcatc caactactat ccaaacatgt
    13681 tagagcaggc catgaaagtc tttggagtgg ctatggataa gccttttgag gacctgtcag
    13741 aagaagataa gaacttgatt ctctatgggt cagatggtaa ggaattccat ttccactatg
    13801 agaatgaatt tggtggcgtg cgcgatatcg acattccgtt tgagggagtt atcaataata
    13861 tcaaacgtcg ttaccatgaa accaatagcg attacactcg cactcagatg cgtctctaca
    13921 tgaatgagct gacctgcgga acctgtcaag gctatcgtct caatgaccag gccttgtctg
    13981 tccgtgtggg cggccagcaa gggccacata ttggagaaat ctcagacctg tctatcgctg
    14041 accacttgga cttggtgagc cagttaactt tgtctgaaaa tgaagccatc attgctcgtc
    14101 ccattctcaa ggaaatcaag gatcgtttga ccttccttaa taatgtgggt cttaactatc
    14161 taaccctgtc acgttcagca ggaacccttt caggtgggga aagtcagcgc attcgtttgg
    14221 caacccagat tggttccaac ctatcaggcg tcctctatat cctagacgag ccgtcaatcg
    14281 gtcttcacca gagggacaat gaccgcctga ttgccagtct gaaaaagatg cgtgacttgg
    14341 gcaatactct tatcgtggtg gaacacgacg aagataccat gcgtgaagct gattatctga
    14401 ttgacgttgg tcctggtgcc ggtgtttttg gtggtgagat tgttgcagca ggtacaccta
    14461 agcaagtggc tcgcaacagc aagtctatca caggtcagta cttgtcaggc aaacgtgtca
    14521 tcccagtacc agaagagcgc cgtgtcggaa atggtcgttt tattgaagtg acaggagcgc
    14581 gtgagaacaa cttgcaaaat gtcacggctc gctttccact aggaaaattt atcgcagtga
    14641 caggtgtgtc gggttcaggg aaatcgactc taatcaacag cattctcaaa aaagccattg
    14701 cccagaagct caaccgtaat tcagacaaac ctggtaagtt taagactatt acagggattg
    14761 agcatgtcga ccgtttgatt gatattgacc agagccctat cggacggacg ccgaggtcta
    14821 acccagctac ctatacagga gtttttgacg atatacgtga cctttttgct cagacaaatg
    14881 aagccaagat tcgaggctac aagaaggggc gcttcagttt caacgtcaag ggaggtcgct
    14941 gtgaagcttg ctcaggtgac gggattatca agattgagat gcacttcttg ccagatgttt
    15001 atgtggcttg tgaagtttgc cacggaaccc gctataacag tgaaacccta gaagttcact
    15061 acaaggaaaa gaatatttcg caggtcttgg atatgacggt caacgatgcg gtagaatttt
    15121 tccaacacat tccgaaaatt caacgcaaac tccagaccat caaggatgta gggctaggct
    15181 atgtgacctt gggacagcca gctaccaccc tttctggggg agaagcccaa cgtatgaagt
    15241 tagctagcga actccacaaa cgctcgacag gaaaatcttt ctacattctg gatgagccga
    15301 cgacagggct tcatacagag gacattgctc gcctgctcaa ggttttagct cgctttgtag
    15361 acgatggcaa tacagtcctc gtcatcgagc acaatctgga tgttatcaag acggcagacc
    15421 atatcattga cttgggacct gagggcggtg tcggtggtgg aaccatcatc gtaacaggaa
    15481 ctccagaaga agtagctgcc aacgaagcca gctatacagg acactatttg aaaggaaagt
    15541 tacatcatga ataaacgcgt acaagcattt ctagctaaaa tgcaagaaaa agaactagat
    15601 ggtatcatca tcaacaatct taaaaacgtc tattatttga ctggtttttg gggctcaaac
    15661 ggaacagtct ttatcagtcg tgaccgtcag gtcttagtga cagactctcg ctatatcatc
    15721 gcagctaagc aagaaaccag tggttttgag attgtggctg atcgtgatga attggctgtc
    15781 attgcaggaa ttgttaagga catgggcttg actcgtatcg gttttgaaga tgagatttca
    15841 gtgtcttatt accaccgtat gcaggcagct tttgcaggtt tggacttgtt tccgcaaact
    15901 cagtttgtgg aaggtcttcg tatgattaag gatgaggcag agattgcagc gattcgcaag
    15961 gcttgttcta tctcagacca agctttccgc gatgcgcttg actttatcaa accaggaaaa
    16021 actgaaattg agattgccaa cttccttgac ttccgcatgc gtgagttggg agcatctggc
    16081 ttatcttttg atacgatcct agctagcggt atcaattctt ctaaacccca tgcccatcca
    16141 atgcacaaac cagtggagtt gggagaagcc attaccatgg acttcggctg tctctatgac
    16201 cactatgtca gtgatatgac ccggactatc tatctagggc atgttagcga tgagcaggca
    16261 gagatttaca atacggttct aaaagctaac caagccttga ttgaccaagc taaggcaggc
    16321 ttaggtttcc gtgactttga caaaatccct cgtgatatta tcattgaggc aggttatggc
    16381 gactacttta ctcacggcat tggccacggt attggtctgg atatccatga ggaaccctac
    16441 tttagccaga cttctacaga aactattaag acaggtatgg ccttgaccga tgaaccaggt
    16501 atctatatcg aaggcaaata tggcgttcgt atcgaggatg atatcctgat tacagagaca
    16561 ggttgtgaat tattgaccct agctccaaaa gagttgatag tcatttagtt gtttgtcaag
    16621 aaaaaagtac gaaaatgacg aaaaaagtca aaaaaaatta aaaataggtc gcaagtcgga
    16681 tgttttttat ggtataatag actaaactga tagtaacatg tagcgaaagg ggtaggtaca
    16741 tgattaaaat ttatacagtc tcaagttgta ctagctgtaa aaaagcaaaa acctggctca
    16801 atgcccacca gttaagttat aaagaacaaa accttggtaa agaaggaatt acgagagaag
    16861 aattactgga tattctaacc aaaacagata acggaatagc cagcatcgtt tcgtctaaaa
    16921 atcgctatgc caaagccctt ggagtggata ttgaagattt gagtgtcaat gaagttctca
    16981 atctgattat ggaaacaccg agaattttaa agagcccaat ccttgtagat gaaaaacgcc
    17041 tgcaagttgg ctacaaggaa gacgatattc gtgccttcct accacgctct gtccgtaatg
    17101 tagaaaatgc agaagcacgt ttacgtgcag ctctataaac atcaaggctg ggagcaattc
    17161 ccagtcttat tctattttaa tttcaaaaag aaagaagaaa gaaatgaaaa aaatagttct
    17221 tgttagtcta gctttccttt ttgtcctggt tggttgcgga cagaaaaaag aaactggacc
    17281 agctacaaaa acagaaaagg atacgcttca gtcggcattg ccagttattg aaaatgccga
    17341 gaagaataca gttgtaacca agactttggt cttgcccaag tcagatgatg gtagccagca
    17401 aactcaaacc attacataca aggacaagac ttttttgagc ttaacgattc aacaaaaacg
    17461 tccagtttct gatgagttga agacttatat tgaccaacat ggagtggaag aaactcaaaa
    17521 agctcttctt gaagcggagg agaaggataa gtctatcatt gaagctcgta aattggtagg
    17581 tttcaaactt gaaacaaaac tattgagcgc aacggaactt caaacaacga ctagttttga
    17641 ttttcaagtt ctggatgtca agaaggcttc ccagttggaa catctgaaga atattggttt
    17701 ggaaaatctt ttgaaaaatg aaccaagcaa atatatttca gacagattgg caaatggtgc
    17761 gacagaacag tagaaaatcc aaataaatag actgcctgaa ttgtagaagg taaggaatta
    17821 tgctataatg gtactattct aaggaaagag ggtgttagaa tgggatttac tgaagaaaca
    17881 gtacgtttta aattggacga ttccaataaa aaagaaatta gcgaaacttt gacagatgtt
    17941 tatgcttcgt tgaacgataa gggttacaac ccaattaacc aaatcgtagg ttacgtattg
    18001 agtggagacc ctgcctacgt tcctcgttat aataatgcac gaaatcaaat ccgtaagtat
    18061 gagcgtgatg aaatcgttga ggaattggtt cgctactacc tcaaaggaca aggagtcgat
    18121 ctataaccta tgagaattat gggattggac gtcggttcaa aaacggtagg ggtggcgatt
    18181 agcgatccgc ttggttttac agctcaaggg cttgaaatca tccagataaa tgaagaacaa
    18241 ggccaatttg gttttgaccg cgttaaggaa ttggttgata cttacaaggt ggaacgattt
    18301 gtagtgggct tgcctaaaaa catgaacaat acaagtggac cgcgcgtaga agctagtcaa
    18361 gcctacggag caaagctaga agagtttttt ggtttaccag tagactatca ggatgaacgc
    18421 ttgacaacag tggctgctga gcgcatgttg attgaacaag cagatatcag tcgcaataag
    18481 cgcaagaaag tcattgataa gttagcagct cagctgattt tacaaaatta tttagataga
    18541 aaattttaat ataaaggaga ggctatgtca cacgatcata accacgacca cgaagaacgt
    18601 gaactaatca cactagtaga tgagcaagga aatgaaacct tgtttgaaat ccttttgaca
    18661 attgatggaa aagaagaatt tggtaaaaac tatgttcttc tagtaccagt taacgcagaa
    18721 gaagacgaag acggacaagt tgaaatccaa gcttactcat tcatcgaaaa cgaagatgga
    18781 acagaaggcg aattgcaacc aatcccagaa gactcagaag acgaatggaa catgattgaa
    18841 gaagtcttca acagctttat ggaggagtga tacagtctgg gagactgtat cagcccaact
    18901 cccagaaatg gggaagagtt ggaacgtcca gtggatgttt ttagcccagt tcctttaaat
    18961 aagagagaac tggtaggttc ggggggacgt ttttagccca gctcctttaa ataagataga
    19021 gctggtaagt ctgggagact gtatcagccc aactcccaga aatggggaag agttggaacg
    19081 tccagtgaac atttttaccc caactcttag aaattgagaa gagttggaac atctagtgga
    19141 tgtttttagc ccatattcac attcatagtg gctagttatt agctaaccag gtaagaggtc
    19201 gggacgaaaa tcctggcctt gtttttatta gtaaccatac tttaatgcga taattgattg
    19261 gacttttgtc aaggagatgt gtatgtttga agtagaagaa tggctccata gtcggattgg
    19321 tttaaatttt cgatcaggtt tgggccgaat gcagcaagcg gtggatttgt taggaaatcc
    19381 tgagcagtct taccctatta tccacgtaac agggactaat gggaaaggat ctaccattgc
    19441 ttttatgagg gaattattta tggggcatgg caaaaaagtt gcgaccttta cctcccctca
    19501 tatcgtctct atcaatgacc gaatctgcat taatgggcaa cctatagcag acgcagactt
    19561 tatccgtttg gctgatcagg tcaaggagat ggagaaaacg cttctgcaaa ctcctgacca
    19621 gttgtccttt tttgaattgc tgaccttggt tgcttttctt tattttaggg agcaagaggt
    19681 ggatttggtt ttattagaag tgggaattgg tggcttactt gacacgacca atgtggtaac
    19741 tggagagctt gctgtcatca cctccattgg gcttgaccat caagaaacct tgggtgatag
    19801 tctagaagca attgcagagc agaaagctgg tattttcaag gctggtaaga aggcagtgat
    19861 tgcgaaattg cctccagaag ctaggcttgt ctgtcagaaa aaagccgaat ctttagctgt
    19921 taacctttat caggcaggtc aagatttttt aatgctgaat ggtgattttt caagctcttt
    19981 actaaatctt tcacagctga acataggctt agaaggagtc tatcagcagg agaatgcagc
    20041 cttggcgttg caaacttttc ttctttttat gggagaagga aaggaagctg ttgatgaaca
    20101 ggctgtaaga aaggccttgg aacagaccca ttgggctggt cgcttggagc gtattcgccc
    20161 acagatttac ttggatggtg ctcataacct ccctgccttg actcgcttgg ttgagtttat
    20221 caaagaaaaa gagcaggaag gctatcgacc tcaaatcctt tttggagcct tgaaacggaa
    20281 ggattatcaa gggatgttag gttacctgac tgaaaaattg cctcaggtgg aactcaaggt
    20341 gaccggcttt gactatcagg gggctttgga cgaaagggat gtgacaggtt acgatatagt
    20401 ttcttcttgc cgagaattta tcagcgattt tgaagaaaga gcagatgctc aggatttgct
    20461 gttcgttaca gggtctctct attttatctc agaagtacgg ggctacctgc tggaccgtga
    20521 gcagataaat tgaccccctt gtttgaactt gttatactag gggaattgct ggttagagaa
    20581 aatttctcta aattggtagc agaaaggaaa ttcatcatga aattaaaaag attcacactt
    20641 tctcttgctt ctctagcaag ttttagtctc ttagtagctt gttcacaaag agctcaacag
    20701 gttcaacagc ctgttgctca gcagcaggtc caacagcctg ctcaacaacc tgctcaacag
    20761 aataccaata ctgcaaatgc aggaggtaac caaaatcaag cggctccagt acaaaaccaa
    20821 cctgttgctc aaccgaccga tattgatggg acttatactg gtcaggatga cggagaccgt
    20881 atcactttag tggtaactgg aacgactggt acatggactg agctcgaatc tgacggggat
    20941 cagaaagtca aacaggttac atttgattca gcaaatcaac gcatgattat tggcgatgat
    21001 gtcaaaattt acactgtaaa cggtaatcaa atcgtcgtag atgatatgga tagagaccca
    21061 tcggaccaaa tcgttttaac taaataagac tatgcaagta gaaagggctg gatttttcag
    21121 cctttttact tttacctaga aaataatcat aaatacttgc cttctaccga atacctgcgt
    21181 tatactagta tcaattactt gtttttagca ttcaaactat caaggagggg atatgaaata
    21241 taggaaattt caattattga tgtccaagta tggctttagt ctttcgatta tgttacttga
    21301 actttgtctt gtttttggtc tctttcttta tttaggacgc atggctccca ttttatggat
    21361 tactgtcctc attctactga gtatcatcac aatcatttcg atagtcaacc gtaatacgac
    21421 tcctgagaat aaggtaacct ggttgttagt agcctttgtg ccagtatttg gtcccttgct
    21481 ctatctgatg tttggtgaaa ggcgattgtc caaaaaagaa atcaaacaac tgaagaagct
    21541 aggctctatg catttccaag aagcaaatag ccagctacta aaagagaaat taaaagaaag
    21601 tgacaaggca gcttatggag tcatcaagtc cttattgagt atggatacca atgctgacat
    21661 ctatgatcaa actgcctcta cattttttcc taacggagaa gctatgtgga aaaagatggt
    21721 agaagatctt aaaaaggctg agaaatttat tttcttggaa tattacatta tagaagaagg
    21781 tttgatgtgg aatcgcatac tagatatact agagcaaaag gtagctcagg gtgtagaggt
    21841 taagatgctc tatgatgata tcggctgtat ggctacttta acaggagatt atgcacatcg
    21901 acttcgtcag ctgggcatcg aggcccataa attcaataaa gttattcctc gtttgacagt
    21961 ggcttataat aacagagatc atagaaaaat attgattgtt gatggtcaga tagcctatac
    22021 tggtgggatc aatctggcag atgagtacat taaccacgtc gagagatttg gttattggaa
    22081 ggatagtgga attcgcttag acggactagc agtaaaagct ctgacacgct tatttttgac
    22141 cacttggtac attaatcgag gagaaattag tgattttgat caatatcatt tagaaaatca
    22201 ttctatcccg agtgacggtt taaccattcc atacggaagt ggacccaagc caatttttcg
    22261 agcgcaggta gggaaaaaag tttatcagag tttaatcaat caagcaacag aatcggtcta
    22321 tattacgaca ccttatttga ttatagatta tgatttaaca gagacaatca aaaatgcagc
    22381 tatgagaggg gtcgatgttc gaattatcac cccttacata ccagataaga agttcattca
    22441 gttagtcacg agaggagctt atcccgacct tctttctgct ggtgttcgga tttatgagta
    22501 tagtccaggt tttattcata gtaagcagat gttggtagac gaagattttg cggtggtggg
    22561 gacaatcaat ctcgactacc ggagcttggt acaccattat gaaaatgcag tcttactcta
    22621 taaaactcct tctataaggg aaatcgcccg agattttcga aatatatttg cagattctca
    22681 ggaagtctat cctcattcta tcaaaacgag ctggtatcaa aagcttgtaa aagaaatcgc
    22741 ccagctattc gcccctatct tataagaaat ctagaactta ggatacaaac cagacctatt
    22801 tttcttgtct tttacgaata gaaagaaaga ggaggggaat tcatgctaac taaggaagaa
    22861 gtgaatgata tgattgagtt caaacagaca catttacacc gctttcggga aattgaaacc
    22921 tttgtgaaac tatgcaaaaa atcactcaaa cagccatcgc aagctgacaa tcctaggact
    22981 ttttgatata ctaagacaga taaattgaac aggagaaacg atatgagtgt gtatggtaga
    23041 gtagaagaag ttcataagga gaatcgtgaa cctctagaat accaaatcga acaagaatcg
    23101 catcatcgtg aatcaagtcg tcttcctttg gtgaaaattt tactatggag tacgcttgta
    23161 acggggataa ctctaggagt accgctatta ctcgacttaa tgagtgcaca agaagtgcag
    23221 gatttttatg caggttgggc gcttcatcag acagggaaga tttacagcga ctattatgga
    23281 agtcaaggtt tgctttatta tttgctgact tacgtgagtc agggcggatt tttctttgcc
    23341 atctttgagt ggttagcctt ggtagcagga ggatttttcc tttttagatc agcggacacc
    23401 ttgacagagc aaggagacca agctggacat ctggtgacta ttttttacat gctagttaca
    23461 ggtcttgctt ttggtggagg ctatgcgact cttttagcgc ttcctttctt attcgcagcc
    23521 tttagtttag ttgcggctta cctaagcaat ccaagccatg ataagggatt tgtacggatt
    23581 gggctagctt tggcaggcgg atttttcttt gctcccttat catcgctcct gtttattgct
    23641 gtagtgagtt taggcttgtt ggtctttaac cttgggcata gacgctttgc gcatgggttt
    23701 tatcagtttc ttgcagtggc tttaggtttt tcacttgtct tttatccaac tgcctactat
    23761 agtgctgcaa caggaagttt tggggatgcg attagtggta ttcgttatcc tattgacagt
    23821 attcgctttg attttacttc taaaatttta gagaatatgt ttttttatgg cttgttgtcc
    23881 cttggtttgg gatttgtggt ttgtatcttt ttaggtctct ttcaatccaa accctttaaa
    23941 ctatacgtca tttcggttcc tgcaagtctt gtggtaattt taggtttgat tttacttttc
    24001 ttttcacaag agcctctgca cgcttcttat ttgatggtcg tcttccctgt tttcctactt
    24061 ttattggtaa ccaatattaa gagtcaacag agggggcgta gtgctagaag aagccgaaga
    24121 gaaacgccag ttagcctatg gagtcgtttc ttcaaaggaa atctatatct gctagttttt
    24181 gagtttgtct atcttttgtc tgttcctttt ttgatgaagt ttgtccttta tccagtacct
    24241 tatcaagaac gtaatcgtct tgctgatttg gtaaaagagg agacaaatac ggaagatgct
    24301 atctatgcat gggatgatac tgcgactctt tatcgtaaga gtgagcgctt gtcgccatcg
    24361 gcgattttgt ccccgttgca ctatacagca actgaggaaa atcgtaataa gttacttaat
    24421 gacttgaaag aaaaacaacc taaggtgatt gtggtaaatg ataaggtggt agtctggtct
    24481 gaagtggaaa cactcttaaa agaaaattac caacaagtaa agactgatta ctcagagttt
    24541 aaagtctata aaattaaata accaaatcaa tatcttgtgt atttttaaaa attttaggat
    24601 ttttaacaca agatattgat ttttcttttt agagtggtat aatacttttt agaaagaaca
    24661 ttttagaaaa gagcatgcat atgattgcac tagaagaaaa aattacaatt ttgccaactc
    24721 tcttcgtcga gaaacgagat gggagacgtg ttgtatttga tgtggacaag attgacaagg
    24781 ctctccacaa ggcggctgac aaggttatgg atgtgacacc cctggttgaa aaacgcctca
    24841 atgatctgac tgagcgaatt attacagaaa ttcatagtcg ctttccacag ggaattaaga
    24901 tttacgaaat tcaaaatatc gtagaacatg aactccttga agccaaagaa tatgcgctgg
    24961 ctgaggagta tattacttat cggacacaga gggattttga gcgctcaaaa gcgacggata
    25021 tcaactttag tattcataaa cttctcaaca aagaccagac agttgtcaat gaaaacgcta
    25081 ataaagacag tgatgtcttt aacactcagc gtgatttgac agcagggatt gttgggaaat
    25141 caatcggact gcaaatgctt cctaagcacg tagccaatgc ccaccaaaag ggggatatcc
    25201 actatcacga tttggactac agtccctata cccctatgac caactgctgt ttgattgatt
    25261 ttaagggtat gttggaaaat ggttttaaga ttggaaatgc agaggtagag agtcccaagt
    25321 ctatccagac tgcgacagca cagatttctc aaatcattgc caacgttgct tctagccagt
    25381 acggtggctg ttcagctgac cgtatcgatg aaattttggc gccttatgca gagaagaatt
    25441 atcaaaaaca tctcaaagat gcagaagagt gggtattgcc tgaaaaacgg gaagattacg
    25501 cttggaagaa aacgcaaaag gacatctacg atgccatgca atctcttgag tatgaaatca
    25561 atactctctt cacttcaaat ggacaaacac cttttacttc gttaggtttt ggtctgggaa
    25621 ccagtcgttt tgaacgagaa attcaaaaag ctattttaaa cattcgcatc aagggtcttg
    25681 gttcagaaca ccgtacggct atctttccta aacttatttt cactctgaaa agaggcctta
    25741 atttagagga aggaactccc aactacgaca tcaagcagtt ggctcttgag tgtgcaacca
    25801 aacggatgta tccagatgtt ttatcttacg ataagattgt tgacttgaca ggatccttca
    25861 aggtgcctat gggttgccgt tctttcctcc aaggatggaa ggatgaaaat ggtgtagaag
    25921 tcaattcagg tcgcatgaat ctgggtgttg tgacggttaa tctgcctcgt attgctcttg
    25981 agtctgaagg tgatatgaat aagttctggg aaatcttcaa cgagcgaatg aatatcgcag
    26041 aagatgctct tgtttaccgt gtcgaacgca ctaaagaggc gacaccagca aatgctccta
    26101 ttctttatca gtacggtgct tttggccatc gtctaggtaa agaagaaagt gttgaccagc
    26161 tctttaagaa tcgtcgtgct accgtttcgc tgggctatat cggcttgtat gaagtagcga
    26221 cagttttctt tggtaacagc tgggaaagta atccagatgc taaggaattc acgctagaca
    26281 tcattcacga tatgaaacgc cgtgtagaag agtggtcaga ccaatatggc taccatttct
    26341 ctatctactc aacaccatcc gaaagtctga cagaccgttt ctgccgacta gatatagaca
    26401 agtttggctc tattcctgat atcacagaca aggaatacta caccaactct ttccactacg
    26461 atgttcgtaa aaatccaaca ccgtttgaaa aattggactt tgagaaagtc tatccagaag
    26521 caggtgcgtc aggtggtttc atccattatt gtgagtatcc agtccttcag caaaatccaa
    26581 aggccttgga agctgtctgg gattatgctt atgaccgtgt aggctatcta ggcaccaata
    26641 ctccgattga ccgttgctac aagtgtgact ttgaagggga ttttgaacca actgagagag
    26701 ggtttgcttg tccaaactgt ggcaatagcg accctaaaac agtagatgtg gtgaagcgaa
    26761 cttgtggcta cctaggtaat cctcaagcaa gaccgatggt caacgggcgt cacaaggaaa
    26821 tcgctgcgcg tgtcaaacat atgaatggtt caacgattaa aatagctggg catcaagtaa
    26881 caaattagaa agaaatgaaa tgggaaaata tcaactagac gataaggggc gcgcacaagt
    26941 gacccgttat cacgagaaac actctaaagg tggagctggt aagaaagaac gcttgcttag
    27001 cttcagagaa caatttttaa acaagaacaa gaaaaaataa aagtgagagc cagctctcgc
    27061 ttttctcata gtgggaggta aggatggaat tacgcagacc aagattagcg gataagaaag
    27121 ctgttttaga tatgatgaca gagtttgaaa agagtcaatc agcccatgat ggaggatttt
    27181 gggatgttga ggatttttct tacgaggagt ggctagaagg taaccgtaat aaagaaatgg
    27241 gaatatggct acctgaaaat cgcgttccat cgatacagtt cgtattgttt ggtgaatcag
    27301 gttgtgctct aggatttttg aatctgcgat tgagactgaa tgaggggtta ctgaattatg
    27361 ctggccacat tggctactcc atccgtccat ctgaaagagg caagggttat gcaaaagaga
    27421 ctctccgtca gggcttgcaa gttgctaagg aaaagaacat caagaaagct ctggtgacct
    27481 gtagcgtgaa taatcttgct agcagagcag tcattctagc aaatggtgga atatttgagg
    27541 atgctcgcaa tggagtcgag cgttattgga tagaggtagc gaatgaataa tccaaaacca
    27601 caagaatgga aaagcgagga acttagtcaa ggtcgtatca ttgactacaa ggcctttaac
    27661 tttgtggacg gcgaaggcgt gcgtaactct ctctatgtat caggctgtat gtttcactgc
    27721 gagggatgtt ataatgttgc gacttggtct tttaatgctg gcattcccta tacagcagaa
    27781 ttagaagagc agatcatggc agatcttgct cagccctatg ttcaaggttt gactttgttg
    27841 ggaggggagc cttttcttaa tactgggatt ctcttgccac ttgttaagcg gattcggaag
    27901 gaattgccag acaaggacat ctggtcctgg accggctaca cttgggaaga aatgatgttg
    27961 gaaactccag ataaactgga attcttgtca ctgattgaca ttcttgtcga tggaagatat
    28021 gatcgaacta agagaaatct tatgctccag tttcgaggtt cgtctaacca acgaattatc
    28081 gatgtgcaaa aatcgctcaa aagtgggcaa gtagtgattt gggacaagct caatgacgga
    28141 aaagaaagct atgaacaggt gaagagagaa tgaagaaaaa agacttagta gaccaactag
    28201 tctcagagat cgagacgggg aaagtcagga cactgggaat atacggtcat ggagcttcag
    28261 gtaaatcaac ctttgcacag gaattgtacc aagctttaga ttctactaca gtaaatttgc
    28321 tagagacaga tccttatatc acctcaggac gccatctggt agtacccaag gacgcgccga
    28381 atcaaaaggt gacagccagt ctgccagtgg cgcatgaact ggagagtttg cagagagata
    28441 tccttgcctt gcaggcgagt atggatgtct tgacaattga agaaccttgg aaggctagtg
    28501 aggtcttgtc tggagccaaa ccaattttga ttgtcgaagg gatgtctgtt ggctttctac
    28561 ccaaggaact ctttgaaaaa accatctgtt tctacacgga tgaggagacc gaattaaagc
    28621 gacgccttgc tagagatacg actgtgagaa atcgcgatgc atcctttata ttggctagcc
    28681 atcagatgag acgggagcag tatctgcgat actataaaga aactgagtct aaggcggata
    28741 tcttagtgga ccaatcagaa gataaatttg atgtcaagag gacttaactt atgtatagaa
    28801 gaaatataga agaaaatccc taattttaga aagaaaaagt aggaaaacag tttcatcccc
    28861 aaaaaacgaa aaaacctaac aaatcccttg caatcgcagg ggatttgtgt tattctatta
    28921 tggtgctgta aattacagcc ttagttttga tgcaagaggt tgcgacacgc tcggttgcat
    28981 tgccacgcaa caccgcgtcg gttttcttgt ggagctagcc tattatctta aatagacgaa
    29041 aaggagaaaa agatggcaaa caaaaaaatc cgtatccgtt tgaaagctta cgaacaccgt
    29101 acgcttgaca cagcggctgc aaaaatcgta gaatcagcta ctcgtacagg tgcacaagtt
    29161 gcgggtccaa tcccacttcc aactgaacgt agcctctaca caatcattcg tgcgactcac
    29221 aaatacaaag actctcgcga acaatttgaa atgcgtacac acaaacgttt gatcgatatc
    29281 gttaacccaa ctcaaaaaac agttgatgcc ttgatgaaat tggatcttcc aagtggtgta
    29341 aacgtagaaa tcaaacttta atctaaaata taaaagagca gaggctggtg tttcaatcta
    29401 attgaacacg ggctaaactc ggtgtgaaaa agataaactt cctcgcgtct gctagacact
    29461 gtgtcagttt cctattttca ctttgagttt gacgcccttt gtatcttaga cttgagcata
    29521 aaaaacgctc gttaaaaact ttttgaataa aaaatataga aaaggaacta ttttctcatg
    29581 acaaaaggaa tcttagggaa aaaagtggga atgactcaaa tcttcactga agctggcgaa
    29641 ttgatccctg taacagttat tgaagcaact ccaaacgttg ttcttcaagt taaaactgtt
    29701 gaaacagacg gatacaacgc tatccaagtt ggtttcgatg acaaacgcga agtattgagc
    29761 aacaaacctg ctaaaggaca tgtagcgaaa gctaacacgg ctcctaagcg cttcattcgt
    29821 gaattcaaaa acgttgaagg cttggaagtt ggtgctgaaa ttacagttga aacattcgca
    29881 gctggagacg ttgttgacgt aactggtact tctaaaggta aaggtttcca aggtgttatc
    29941 aaacgccacg gacaatcacg tggaccaatg gctcacggtt ctcgttacca ccgtcgtcca
    30001 ggttctatgg gacctgttgc acctaaccgc gtattcaaag gtaaaaacct tgcaggacgt
    30061 atgggtggtg accgcgtaac aattcaaaat cttgaagttg tacaagttgt tccagaaaag
    30121 aacgttatcc ttatcaaagg taacgtacca ggtgctaaga aatctcttat cactatcaaa
    30181 tcagcagtta aagctggtaa ataataaaga aaggggaaat cagtcacaat ggcaaacgta
    30241 acattatttg accaaactgg taaagaagct ggccaagttg ttcttagcga tgcagtattt
    30301 ggtatcgaac caaatgaatc agttgtgttt gatgtaatca tcagccaacg cgcaagcctt
    30361 cgtcaaggaa cacacgctgt taaaaaccgc tctgcagtat caggtggtgg acgcaaacca
    30421 tggcgtcaaa aaggaactgg acgtgctcgt caaggttcta tccgctcacc acaatggcgt
    30481 ggtggtggtg ttgtcttcgg accaactcca cgttcatacg gctacaaact tccacaaaaa
    30541 gttcgtcgcc tagctcttaa atcagtttac tctgaaaaag ttgctgaaaa caaattcgta
    30601 gctgtagacg ctctttcatt tacagctcca aaaactgctg aatttgcaaa agttcttgca
    30661 gcattgagca tcgattctaa agttcttgtt atccttgaag aaggaaatga attcgcagct
    30721 ctttcagctc gtaaccttcc aaacgtgaaa gttgcaactg ctacaactgc aagtgttctt
    30781 gacatcgcaa atagcgacaa acttcttgtc acacaagcag ctatctctaa aatcgaggag
    30841 gttcttgcat aatgaatttg tatgatgtta tcaaaaaacc tgtcatcact gaaagctcaa
    30901 tggctcaact tgaagcaggg aaatatgtat ttgaagttga cactcgtgca cacaaacttt
    30961 tgatcaagca agctgttgaa gctgctttcg aaggtgttaa agttgccaat gttaacacaa
    31021 tcaacgtaaa accaaaagct aaacgtgttg gacgttacac tggttttact aacaaaacta
    31081 aaaaagctat catcacactt acagctgatt ctaaagcaat cgagttgttt gctgctgaag
    31141 ctgaataatc taaggaggaa atatcgtggg aattcgtgtt tataaaccaa caacaaacgg
    31201 tcgccgtaat atgacttctt tggatttcgc tgaaatcaca acaagcactc ctgaaaaatc
    31261 attgcttgtt gcattgaaga gcaaggctgg tcgtaacaac aacggtcgta tcacagttcg
    31321 tcaccaaggt ggtggacaca aacgtttcta ccgtttggtt gacttcaaac gtaataaaga
    31381 caacgttgaa gcagttgtta aaacaatcga gtacgatcca aaccgttctg caaacatcgc
    31441 tcttgtacac tacactgacg gtgtgaaagc atacatcatc gctccaaaag gtcttgaagt
    31501 aggtcaacgt atcgtttcag gtccagaagc agatatcaaa gtcggaaacg ctcttccact
    31561 tgctaacatc ccagttggta ctttgattca caacatcgag ttgaaaccag gtcgtggtgg
    31621 tgaattggta cgtgctgctg gtgcatctgc tcaagtattg ggttctgaag gtaaatacgt
    31681 tcttgttcgt cttcaatcag gtgaagttcg tatgattctt ggaacttgcc gtgctacagt
    31741 tggtgttgtc ggaaacgaac aacatggact tgtaaacctt ggtaaagcag gacgtagccg
    31801 ttggaaaggt atccgcccaa cagttcgtgg ttctgtaatg aaccctaacg atcacccaca
    31861 cggtggtggt gaaggtaagg caccagttgg tcgtaaagca ccatctactc catggggcaa
    31921 acctgctctt ggtcttaaaa ctcgtaacaa gaaagcgaaa tctgacaaac ttatcgttcg
    31981 tcgtcgcaac gagaaataat attaaactag tcgcttaagc aactagtaaa tccgccagct
    32041 cggtagcgct ccataggagt gcaagccgct gtggtacaac atttaaagga gaaaatataa
    32101 aaatgggacg cagtcttaaa aaaggacctt tcgtcgatga gcatttgatg aaaaaagttg
    32161 aagctcaagc taacgacgaa aagaaaaaag ttattaaaac ttggtcacgt cgatcaacga
    32221 tcttcccaag tttcattggt tacactattg cagtttatga cggacgtaaa cacgtacctg
    32281 tttacatcca agaagacatg gtaggccaca aacttggtga atttgcacca actcgtactt
    32341 acaaaggtca cgctgcagac gacaagaaaa cacgtagaaa ataaggagaa cataaatggc
    32401 agaaattact tcagctaaag caatggctcg tacagtacgt gtttcacctc gtaaatcacg
    32461 tcttgttctt gataacatcc gtggtaaaag cgtagccgat gcaatcgcaa tcttgacatt
    32521 cactccaaac aaagctgctg aaatcatctt gaaagttttg aactcagctg tagctaacgc
    32581 tgaaaacaac tttggtttgg ataaagctaa cttggtagta tctgaagcat tcgcaaacga
    32641 aggaccaact atgaaacgtt tccgtccacg tgcgaaaggt tcagcttcac caatcaacaa
    32701 acgtacagct cacatcactg tagctgttgc agaaaaataa ggaggtaaaa tcgtgggtca
    32761 aaaagtacat ccaattggta tgcgtgtcgg catcatccgt gattgggatg ccaaatggta
    32821 tgctgaaaaa gaatacgcgg attaccttca tgaagatctt gcaatccgta aattcgttca
    32881 aaaagaactt gctgacgcag cagtttcaac tattgaaatc gaacgcgcag taaacaaagt
    32941 taacgtttca cttcacactg ctaaaccagg tatggttatc ggtaaaggtg gtgctaacgt
    33001 tgatgcactc cgtgcaaaac ttaacaaatt gactggaaaa caagtacaca tcaacatcat
    33061 cgaaatcaaa caacctgatt tggatgctca ccttgtaggt gaaggaattg ctcgtcaatt
    33121 ggagcaacgt gttgctttcc gtcgtgcaca aaaacaagca atccaacgtg caatgcgtgc
    33181 tggagctaaa ggaatcaaaa ctcaagtatc aggtcgtttg aacggtgcag atatcgcccg
    33241 tgctgaagga tactctgaag gaactgttcc gcttcacaca cttcgtgcag atatcgatta
    33301 cgcttgggaa gaagcagata ctacatatgg taaacttggt gttaaagtat ggatctaccg
    33361 tggtgaagtt cttccagctc gtaaaaacac taaaggaggt aaataaccaa tgttagtacc
    33421 taaacgtgtt aaacaccgtc gtgaattccg tggaaaaatg cgcggtgaag caaaaggtgg
    33481 aaaagaagta gcattcggtg aatacggtct tcaagctaca actagccact ggatcactaa
    33541 ccgccaaatc gaagctgctc gtatcgccat gactcgttac atgaaacgtg gtggtaaagt
    33601 ttggattaaa atcttcccac acaaatcata cactgctaaa gctatcggtg tgcgtatggg
    33661 atctggtaaa ggggcacctg aaggttgggt agcaccagtt aaacgtggta aagtgatgtt
    33721 cgaaatcgct ggtgtatctg aagagattgc acgtgaagcg cttcgacttg ctagccacaa
    33781 attgccagtt aaatgtaaat tcgtaaaacg tgaagcagaa taaggagaag gcatgaaact
    33841 taatgaagta aaagaatttg ttaaagaact tcgtggtctt tctcaagaag aactcgcgaa
    33901 gcgcgaaaac gaattgaaaa aagaattgtt tgaacttcgt ttccaagctg ctactggtca
    33961 attggaacaa acagctcgct tgaaagaagt taaaaaacaa atcgctcgta tcaaaacagt
    34021 tcaatctgaa gcgaaataat agactaggga aggagaaatt tcaatggaac gcaataatcg
    34081 taaagttctt gttggacgtg ttgtatctga caaaatggac aagacaatca cagttgtagt
    34141 tgaaacaaaa cgtaaccacc cagtctatgg taaacgtatt aactactcta aaaaatacaa
    34201 agctcatgat gaaaacaatg ttgccaaaga aggcgatatc gtacgtatca tggaaactcg
    34261 cccgctttca gctacaaaac gtttccgtct tgtagaagtt gttgaagaag cggtcatcat
    34321 ctaatcaaac ctgaaaggag aaaactgaaa tgattcaaac agaaactcgt ttgaaagtcg
    34381 cagacaacag cggtgctcgc gaaatcttga ctatcaaagt tcttggtggt tcaggacgta
    34441 aatttgcaaa catcggtgat gttatcgtgg catctgtaaa acaagctact cctggtggtg
    34501 cggttaaaaa aggtgacgtt gttaaagcag ttatcgttcg tactaaatca ggtgctcgtc
    34561 gtgctgatgg ttcatacatc aaatttgacg aaaacgcagc agttatcatc cgtgaagaca
    34621 aaactcctcg cggaacacgt atctttggcc cagttgcacg tgaattgcgt gaaggtggct
    34681 tcatgaagat cgtgtcactt gctccagaag tactttaatt tttaggaaca aactagtccc
    34741 ctagcttcaa gctagggtgc ccttatgggc gtaagaaaaa tcaaggagaa acctaatgtt
    34801 tgtaaaaaaa ggcgacaaag ttcgcgtaat cgctggtaaa gataagggaa cagaagctgt
    34861 tgtccttact gcccttccaa aagtaaacaa agttatcgtt gaaggtgtta acattgttaa
    34921 gaaacaccaa cgtccaacta acgagcttcc tcaaggtggt atcatcgaga aagaagcagc
    34981 tatccacgta tcaaatgttc aagttttgga taaaaatggt gtagctggtc gtgttggtta
    35041 caaatttgta gacggtaaaa aagttcgcta caacaaaaaa tcaggcgaag tgcttgatta
    35101 atcacgaagg aaaggagaag tataatggca aatcgtttaa aagaaaaata tcttaatgaa
    35161 gtagttcctg ctttgacaga acaattcaac tactcatcag tgatggctgt gcctaaagta
    35221 gataagattg ttttgaacat gggtgttggt gaagctgtat caaacgctaa aagccttgaa
    35281 aaagctgctg aagaattggc acttatctca ggtcaaaaac cacttatcac taaagctaaa
    35341 aaatcaatcg ccggcttccg tcttcgtgaa ggtgttgcga tcggtgcaaa agttaccctt
    35401 cgtggtgaac gtatgtacga attcttggat aaattggtat cagtttcact tccacgtgta
    35461 cgtgacttcc acggtgtccc aacaaaatca tttgatggac gcgggaacta cacacttggt
    35521 gtgaaagaac aattaatctt cccagaaatc aacttcgatg acgttgacaa aactcgtggt
    35581 cttgacatcg ttatcgtaac aactgctaac actgacgaag agtcacgtgc attgcttaca
    35641 ggccttggaa tgccttttgc aaaataatat aggaggtaaa tctaatggct aaaaaatcaa
    35701 tggtagctag agaggctaaa cgccaaaaaa ttgttgaccg ttatgctgaa aaacgtgctg
    35761 cattaaaggc ggcaggggac tacgaaggtt tatctaaatt acctcgcaac gcctcaccga
    35821 ctcgtttaca taatcgttgt agggttacgg ggcgcccaca ttcagtttac cgcaaatttg
    35881 gtctgagtcg tatcgctttt cgcgaacttg cgcataaagg tcaaattcct ggtgtaacaa
    35941 aagcatcttg gtaatttaag atatcaagag tgtcaaaact ccaagtaaaa ataggaaact
    36001 tgacgaagaa actaaagttt ctaggaaagt ttatcttttt cacacagagt ttagcccggg
    36061 ttcaattggg cttgccaatt tgaacacgag ctacagcttt ggcaaaaaag accaatttgc
    36121 tttggagcat tgcttctgca ttaaattgtc tatttttgct cgtgctgtta cgctctttgt
    36181 atcatgtatt aactagcaag tgcaacttgc aaactactag taagaggaga aaaacaaaat
    36241 ggttatgact gacccaatcg cagacttcct aactcgtatt cgtaatgcta accaagctaa
    36301 acacgaagta cttgaagtac ctgcatcaaa catcaaaaaa gggattgctg aaatccttaa
    36361 acgcgaaggt tttgtaaaaa acgttgaaat cattgaagat gacaaacaag gcgtcatccg
    36421 tgtatttctt aaatacggac caaatggtga gaaagttatc actaacttga aacgtgtttc
    36481 taaaccagga cttcgtgtct acaaaaaacg tgaagacctt ccaaaagttc ttaacggact
    36541 tggaattgcc atcctttcaa cttctgaagg tttgcttact gataaagaag cacgccaaaa
    36601 gaatgttggt ggtgaggtta tcgcttacgt ttggtaaaat caagatacaa agctcgtaaa
    36661 gaacaaagca aaattaggaa gttggagaag tttgtttaca aacaagccaa cttatctatt
    36721 ttgcacagtt cttagagcgt gttcagttca gctcttgaac taaataagta tctgaacccc
    36781 gtgaaaactg gccgttctgg cctgacaatt taacaggaga aaataaacat gtcacgtatt
    36841 ggtaataaag ttatcgtgtt gcctgctggt gttgaactcg ctaacaatga caacgttgta
    36901 actgtaaaag gacctaaagg agaacttact cgtgagttct caaaagatat tgaaatccgt
    36961 gtggaaggta ctgaaataac tcttcaccgt ccaaacgatt caaaagaaat gaaaactatc
    37021 cacggaacta ctcgtgccct tttgaacaac atggttgttg gtgtatcaga aggattcaag
    37081 aaagaacttg aaatgcgtgg ggttggttac cgtgcacagc ttcaaggatc taaacttgtt
    37141 ttggctgttg gtaaatctca tccagacgaa gttgaagctc cagaaggaat tacttttgaa
    37201 cttccaaacc caacaacaat cgttgttagc ggaatttcaa aagaagtagt tggtcaaaca
    37261 gctgcttacg tacgtagcct tcgttcacca gaaccatata aaggtaaagg tatccgttac
    37321 gttggtgaat tcgttcgccg taaagaaggt aaaacaggta aataatgttg agtggttgat
    37381 catcaaccac caacctattt tccaactttg tgcatagcac acgatttaaa actaaagagg
    37441 tgaaaactgt gatttcaaaa ccagataaaa acaaactccg ccaaaaacgc caccgtcgcg
    37501 ttcgcggaaa actctctgga actgctgatc gcccacgttt gaacgtattc cgttctaata
    37561 caggcatcta cgctcaagtg attgatgacg tagcgggtgt aacgctcgca agtgcttcaa
    37621 ctcttgataa agaagtttca aaaggaacta aaactgaaca agccgttgct gtcggtaaac
    37681 tcgttgcaga acgtgcaaac gctaaaggta tttcagaagt ggtgttcgac cgcggtggat
    37741 atctatatca cggacgtgtg aaagctttgg ctgatgcagc tcgtgaaaac ggattgaaat
    37801 tctaatagga ggacactaga aaatggcatt taaagacaat gcagttgaat tagaagaacg
    37861 cgtagttgct gtcaaccgtg ttacaaaagt tgttaaaggt ggacgtcgtc ttcgtttcgc
    37921 agctcttgtt gttgttggtg accacaatgg tcgcgtagga tttggtactg gtaaagctca
    37981 agaagttcca gaagcaatcc gtaaagcagt agatgatgct aagaaaaact tgatcgaagt
    38041 tcctatggtt ggaacaacaa tcccacacga agttctttca gaattcggtg gagctaaagt
    38101 attgttgaaa cctgctgtag aaggttctgg agttgccgct ggtggtgcag ttcgtgccgt
    38161 tgtggaattg gcaggtgtgg cagatattac atctaaatca cttggttcta acactccaat
    38221 caacattgtt cgtgcaactg ttgaaggttt gaaacaattg aaacgcgctg aagaaattgc
    38281 tgcccttcgt ggtatttcag tttctgattt ggcataagaa aggggataaa atggctcaaa
    38341 ttaaaattac tttgactaag tctccaatcg gacgcattcc atcacaacgt aaaactgttg
    38401 tagcacttgg acttggcaaa ttgaacagct ctgttattaa agaagataac gctgctatcc
    38461 gtggtatgat cacagcagta tctcacttag taacagttga agaagtaaac taatgaagtt
    38521 ttaggggatg tgcactgtac catcccctaa aactagatat agtcatctat gatgacatcg
    38581 tataggcgag ttgatggggg agacaacctt ttctccctta tcggcgctag cattttacaa
    38641 aagaggagaa aataaaaatg aaacttcatg aattgaaacc tgcagaaggt tctcgtaaag
    38701 tacgtaaccg cgttggtcgt ggtacttcat caggtaacgg taaaacatct ggtcgtggtc
    38761 aaaaaggtca aaaagctcgt agcggtggcg gagttcgcct tggttttgaa ggtggacaaa
    38821 ctccattgtt ccgtcgtctt ccaaaacgtg gattcactaa catcaacgct aaagaatacg
    38881 caattgtgaa ccttgaccaa ttgaacgtct ttgaagatgg tgctgaagta actccagttg
    38941 ttcttatcga agcaggaatt gttaaagctg aaaagtcagg tattaaaatt cttggtaacg
    39001 gtgagttgac taagaaattg actgtgaaag cagctaaatt ctctaaatca gctgaagaag
    39061 ctatcactgc taaaggtggt tcagtagaag tcatctaaga gaggtgacct atgtttttta
    39121 aattattaag agaagctctt aaagtcaagc aggttcgatc aaaaatttta tttacaattt
    39181 ttatcgtttt ggtctttcgt atcggaacta gcattacagt tcctggtgtg aatgccaata
    39241 gcttgaatgc tttaagtgga ttatccttct taaacatgtt gagcttggtg tcggggaatg
    39301 ccctaaaaaa cttttcgatt tttgccctag gagttagtcc ctatatcact gcttctattg
    39361 ttgtccaact cttgcaaatg gatattttac ccaagtttgt agagtggggt aaacaagggg
    39421 aagtaggtcg aagaaaattg aatcaagcta ctcgttatat tgctctagtt ctcgcttttg
    39481 tgcaatctat cgggattaca gctggtttta ataccttggc tggagctcaa ttgattaaaa
    39541 ctgctttaac tccacaagtt tttctgacga ttggtatcat cttaacagct ggtagtatga
    39601 ttgtcacttg gttgggtgag caaattacag ataagggata cggaaacggt gtttccatga
    39661 ttatctttgc cgggattgtt tcctcaattc cagagatgat tcagggcatc tatgtggact
    39721 actttgtgaa cgtcccaagt agccgtatca cttcatctat cattttcgta atcattttga
    39781 ttattactgt attgttgatt atttacttta caacttatgt tcaacaagca gaatacaaaa
    39841 ttccaatcca atatactaag gttgcacaag gtgctccatc tagctcttac cttccgttaa
    39901 aggtaaatcc tgctggagtt atccctgtta tctttgccag ttcgattact gcagcgcctg
    39961 cggctattct tcagtttttg agtgccacag gtcatgattg ggcttgggta agggtagcac
    40021 aagagatgtt ggcaactact tctccaactg gtattgccat gtatgctttg ttgattattc
    40081 tctttacatt cttctatacg tttgtacaga ttaatcctga aaaagcagca gagagcctac
    40141 aaaagagtgg tgcctatatc catggagttc gtcctggtaa aggtacagaa gaatatatgt
    40201 ctaaacttct tcgtcgtctt gcaactgttg gttccctctt ccttggtgtg atttccattt
    40261 taccgattgc agctaaagat gtatttggtc tttctgatgt tgttgccttt ggtggaacaa
    40321 gtctcttgat cattatctct acaggtatcg aaggaatcaa gcaattggaa ggttacctat
    40381 tgaaacgtaa gtatgttggt ttcatggaca gaacagaata aaagtattta ctgaatcagt
    40441 aaatgctgag ggagtggagg tttaaactct gacatttgta agagttggat ctcccctctt
    40501 ctattttgtt tttaaatagg ggtgaaaaga ctttttgctt ctatttaaaa ataaaataag
    40561 gagatcaaat catgaatctt ttgattatgg gcttacctgg tgcaggtaag ggaactcaag
    40621 cagcaaaaat cgtagaacaa ttccatgttg cacatatctc aacaggtgat atgttccgcg
    40681 ctgcaatggc aaatcaaact gaaatgggtg ttcttgctaa gtcatatatt gacaagggtg
    40741 aattggttcc tgacgaagtt acaaatggaa tcgtaaaaga acgcctttca caagatgata
    40801 ttaaagaaac aggattctta ttggatggtt acccacgtac aattgaacaa gctcatgcct
    40861 tggacaaaac attggctgaa cttggcattg aactagaagg tgttatcaat attgaagtga
    40921 accctgacag cctcttggaa cgtttgagtg gccgtatcat ccaccgcgta actggagaaa
    40981 ctttccacaa ggtctttaac ccaccagttg actataaaga agaagattac taccaacgtg
    41041 aagatgataa gcctgagaca gtaaaacgtc gtttggatgt taatattgct caaggagaac
    41101 caatcattgc tcactaccgt gccaaaggtt tggttcatga catcgaaggt aatcaagata
    41161 tcaatgatgt cttctcagat attgaaaaag tattgacaaa tttgaaataa agcgtttttc
    41221 atacttgcaa aaattcgcta caaatgttat actgagatag tctgacttat aattgttgtc
    41281 tctgtgtcta gaggcatcga atcgaaattt atggaggtgc ttttgcgtgg caaaagacga
    41341 tgtgattgaa gttgaaggca aagtagttga tacaatgccg aatgcaatgt ttacggttga
    41401 acttgaaaat ggacatcaga ttttagcaac agtttctggt aaaattcgta aaaactatat
    41461 tcgtatttta gcgggagatc gtgttactgt cgaaatgagt ccatatgact tgacacgtgg
    41521 acgtatcact taccgcttta aataatcgaa aaacttggag ggataagaaa tgaaagtaag
    41581 accatcggtc aaaccaattt gcgaatactg taaagttatt cgtcgtaatg gtcgtgttat
    41641 ggtaatttgc ccagcaaatc caaaacacaa acaacgtcaa ggataagata gaaaggagaa
    41701 aacatggctc gtattgctgg agttgatatt ccaaatgaca aacgcgtagt aatctcattg
    41761 acttatgttt atggtatcgg acttgcaaca tctaagaaaa ttttggctgc tgctggaatc
    41821 tcagaagatg ttcgtgtacg tgatcttaca tcagatcaag aagatgctat ccgtcgtgaa
    41881 gtggatgcaa tcaaagttga aggtgacctt cgtcgtgaag taaacttgaa catcaaacgt
    41941 ttgatggaaa tcggttcata ccgtggtatc cgtcaccgtc gtggacttcc tgtccgtgga
    42001 caaaacacta aaaacaacgc tcgcactcgt aaaggtaaag ctgttgcgat tgctggtaag
    42061 aaaaaataat ataggaggta aaagtcttgg ctaaaccaac acgtaaacgt cgtgtgaaaa
    42121 agaatatcga atctggtatt gctcatattc acgctacatt taataacact attgttatga
    42181 ttactgatgt gcatggtaat gcaattgctt ggtcatcagc tggtgctctt ggtttcaaag
    42241 gttctcgtaa atctacacca ttcgctgctc aaatggcttc tgaagctgct gctaaatctg
    42301 cacaagaaca cggtcttaaa tcagttgaag ttactgtaaa aggtccaggt tctggtcgtg
    42361 agtcagctat tcgtgcgctt gctgccgctg gtcttgaagt aacagcaatt cgtgatgtga
    42421 ctccagtgcc acacaatggt gctcgtcctc caaaacgtcg ccgtgtataa tcatcgcatt
    42481 acactgcttt tcgtttaaga gggagtaact aaatgatcga gtttgaaaaa ccaaatataa
    42541 caaaaattga tgaaaataaa gattatggca agtttgtaat cgaaccactt gaacgtggct
    42601 acggtacaac tcttggtaac tctcttcgtc gtgtacttct agcttctcta ccaggagcag
    42661 ctgtgacatc tatcaacatt gatggtgtgt tacatgagtt tgacacagtt ccaggtgttc
    42721 gtgaagacgt gatgcaaatc attctgaaca ttaaaggaat tgcagtgaaa tcgtacgttg
    42781 aagacgaaaa aatcatcgaa ctggatgttg aaggtcctgc tgaagtaaca gctggtgaca
    42841 ttttgacaga tagcgatatt gaaattgtaa atccagatca ttatctcttt acaatcggtg
    42901 aaggttcttc tctaaaagcg actatgactg ttaacagtgg tcgtggatat gtacctgctg
    42961 atgaaaataa aaaggataat gcaccagttg gaacacttgc tgtagattct atttatacac
    43021 cagttacaaa agtcaactat caagtggaac ctgctcgtgt aggtagcaat gatggtttcg
    43081 acaaattaac ccttgaaatc ttgacaaatg gaacaattat tccagaagat gctttagggc
    43141 tttcagcacg tattttgaca gaacatcttg atttgtttac aaatcttact gagattgcta
    43201 agtcaactga agtgatgaaa gaagctgata ctgaatctga cgaccgtatt ttagatcgta
    43261 cgattgagga actggacttg tctgtgcgtt catacaactg tttaaaacgt gccggtatca
    43321 atactgtgca tgatttgaca gaaaaatctg aagcagagat gatgaaagta cgaaatcttg
    43381 gacgcaagag tttggaagaa gtgaaactca aactcattga tttgggtctt ggattaaaag
    43441 ataaataaag gaggaataca tggcttaccg taaactagga cgcactagct cacaacgtaa
    43501 agcaatgctt cgcgatttga caactgacct tttgatcaac gaatcaatcg tgacaactga
    43561 agctcgtgct aaagaaatcc gtaaaactgt tgaaaaaatg attactctag gtaaacgtgg
    43621 tgatttgcat gcacgtcgtc aagcagctgc tttcgtacgt aatgaaatcg catctgaaaa
    43681 ctatgatgaa gcaactgata agtacacttc tactacagca cttcaaaaat tgttctcaga
    43741 aatcgcacct cgttatgctg aacgtaacgg tggatacact cgtatcctta aaactgaacc
    43801 acgtcgtggt gatgcagcgc caatggcgat catcgaatta gtataaaatc atcaattttg
    43861 ttgagtgtta tgatgatgga gtcttgtgct cttagtctag ctctggtcta ccgctaggat
    43921 ttcggtccta gcgggaacac tcatcataag ttgggatagt agacgcttgt ttacgaaatt
    43981 gtttttttct taagaacaac ttcgtaagca ggcgtttttg agtattttcg ttagaattat
    44041 gctatactat ttgaaaagaa tcctgtttaa tgttaaggtt tcttatttta agaagaattg
    44101 gagtttactt atgaaagcca ttataactgt tgttggtaaa gataaatctg gaattgttgc
    44161 aggtgtttct ggtaaaattg cagaattagg attgaatatt gacgatatct ctcaaactgt
    44221 attggatgaa tattttacga tgatggctgt tgtatctagt gatgaaaagc aagattttac
    44281 ctatcttcgt aatgaatttg aagcttttgg gcaaactttg aatgtaaaaa tcaatattca
    44341 gagtgcagcg attttcgaag ctatgtataa tatctaggag gtcatcatgg atattagaca
    44401 agttactgaa accatcgcca tgattgagga gcaaaacttc gatattagaa ccattaccat
    44461 ggggatttct cttttggact gtatcgatcc aaatatcaat cgtgctgcgg agaaaatcta
    44521 tcaaaaaatt acgacaaagg cggctaattt agtagctgtt ggtgatgaaa ttgcggctga
    44581 gttgggaatt cctatcgtta ataagcgtgt atcggtgaca cctatttctc tgattggggc
    44641 agcgacagat gcgacggact acgtggttct ggcaaaagcg cttgataagg ctgcgaaaga
    44701 gattggtgtg gactttattg gtggtttttc tgccttagta caaaaaggtt atcaaaaggg
    44761 agatgagatt ctcatcaatt ccattcctcg cgctttggct gagacggata aggtctgctc
    44821 gtcagtcaat atcggctcaa ccaagtctgg tattaatatg acggctgtgg cagatatggg
    44881 acgaattatc aaggaaacag caaatctttc agatatggga gtggccaagt tggttgtatt
    44941 cgctaatgct gttgaggaca atccatttat ggcgggtgcc tttcatggtg ttggggaagc
    45001 agatgttatc atcaatgtcg gagtttctgg tcctggtgtg gtgaaacgtg ctttggaaaa
    45061 agttcgtgga cagagctttg atgtagtagc cgaaacagtt aagaaaactg cctttaaaat
    45121 cactcgtatc ggtcaattgg ttggtcaaat ggccagtgag agactgggtg tggagtttgg
    45181 tattgtggac ttgagtttgg caccaacccc tgcggttgga gactctgtgg cacgtgtcct
    45241 tgaggaaatg gggctagaaa cagttggcac gcatggaacg acagctgcct tggccctctt
    45301 gaacgaccaa gttaaaaagg gtggagtgat ggcctgtaac caggtcggtg gtctatctgg
    45361 tgcctttatc cctgtttctg aggatgaagg aatgattgct gcagtgcaaa atggctctct
    45421 taatttagaa aaactagaag ctatgacggc tatctgttct gttggattgg atatgattgc
    45481 catcccagaa gatacgcctg ctgaaactat tgcggctatg attgcggatg aagcagcaat
    45541 cggtgttatc aacatgaaaa caacagctgt tcgtatcatt cccaaaggaa gagaaggcga
    45601 tatgattgag tttggtggtc tattaggaac tgcacctgtt atgaaggtta atggggcttc
    45661 gtctgtcgac ttcatctctc gcggtggaca aatcccagca ccaattcata gttttaaaaa
    45721 ttaagaaaat aggagaaatt ttaagttcta tttaagatta gacgtgtata ctataatcat
    45781 taaataaaga cctcctaata ttatttgaaa cagataacac tgaattagtt tgaatttgat
    45841 tttcatctaa tatctttatt taatgaactc ctaaactttt tcataataat ctccttcaaa
    45901 agtcgcctgt atgggtggct tttattttat cattcatgat ataatagaag caaacggagg
    45961 acggaaaatg gtaaaagtac gattgtattt ggtacgtcat ggcaagacca tgtttaacac
    46021 gattggtcgc gcgcaaggtt ggagcgatac tcccttaact gctgaaggtg aacgagggat
    46081 tcaagagtta ggaattggtt tgcgagaatc tgatctacag tttgagcgcg cttattcgag
    46141 tgattctggt cgtaccattc agaccatggg aattatcctt gaagaacttg gcttgcaggg
    46201 gaaaatccct tatcgcatgg acaagcgtat cagagaatgg tgtttcggta gttttgatgg
    46261 agcctatgat ggcgatcttt tcatgggcat tattcctcgt atctttaatg tggaccacgt
    46321 tcaccaattg tcttatgctg aactggctga gggcttggta gaggtcgata cagctggttg
    46381 ggctgaaggc tgggaaaaac tcagtggccg aatcaaggaa ggctttgaaa tgattgcaaa
    46441 agaaatggaa gatcaaggtg gaggtaacgc ccttgttgtc agccatggaa tgactattgg
    46501 aaccattgtt tatctgatta atggcatgca tccgcatggt ctagataatg gtagcgtgac
    46561 gattcttgaa tatgaggacg gtcagtttag ggttgaagtt gtcggtgacc gtagttaccg
    46621 agagctagga cgtgagaaga tggaagaagg ctctatttaa tcagtctaga cttgcttgcc
    46681 atgagctagg gatttgataa gaatatcaag ataagaaaaa acagccgagg gtactccttt
    46741 cggctgtttt tgatgtggaa aactaaagtg taatgctatt gcttttagag attttcataa
    46801 acaagagcaa ggaacctact gttagaacag tcaggatagt tgacaaggct gcggctacac
    46861 cgtaatttcc tctgagaacc tctgtataaa tagctacagt cattgttctt gttttgacat
    46921 tgtagaggag gatagaagta gagagttttg aaatcattat gacctaagat aagatggctc
    46981 cagaaatgat accagatagc atcattggag ttgtaatctt agcaaaggta ttgagacgac
    47041 tacttcctaa gctttcagca gcttcttcaa tacttggtgc tatttgttgt aagctagcaa
    47101 cagatgagcg aatagtataa ggtaatcttc tgacagatag agacataatc aagatgaaag
    47161 cagtccctgt aatcataaga aatccacttc caaatagacc agtattgaag gaagaaatga
    47221 aggcaatccc tagaacggtt cctggtacaa tataaggtac catactgagg ctgtcaatta
    47281 agtttgtaaa caaattccgt tttctaacgg ctaggtagga gataaatgtc gcaaatagaa
    47341 caactagaac taaggcaatc aaagggatac gaatggtatt gaaaatagca gatcccatac
    47401 gattgaaagc taccttgtaa ctgtttggag aataaccttt aacagatacc atacctgatg
    47461 tttttaggaa agaggtataa attaagtaga tttgaggtaa aacagagata aagataattc
    47521 cgtagactgt tgcataaatg gcagctattt ttccttttgt agttttttta ggctcaattg
    47581 gatggagcag attcatgctg aaactgtagc ggtttgcaat gtgtttttgg ataaggaaaa
    47641 ttgccaagac aatgataatc gccataattg caaaagcaga atttcctcca acctcgctaa
    47701 taaattgggt ataaatcagg acagggaagg tccgatatcc ttcgccaatc aacataggcg
    47761 ttccaaagtc tgagaatgct ctcataaata caagcaagga gctgctagta aggttggaac
    47821 taggagaggt aaaacaaccg ttacgatagg tttaaatccg aaggacccca tgctttcagc
    47881 tgcttcaagt agagaattgt caatactgtt cattgttcca gcaacatata gaaataccag
    47941 tgggaatagt tgcagtgtaa agacaagtac aattcctttg aatccataaa tatcgatagc
    48001 tggaagatga agggcatttg tcaaaaattt agtgatgacc ccatttcgtc ctagcaagag
    48061 aacccaggag taggctccta cgaaaggagc tgacatggaa gcaatgataa tcaatatttg
    48121 tagaaatttc ttccccttga agtcatacat agagaagaga taagctaata gggttcctac
    48181 aactaaggaa gtgacagtag cggtaatgga aaccttgaaa ctgttgacta gtgtctcaga
    48241 gtagtagact ttactaaaga aagtgacaaa attagctagt gagaattgtc cttcatgtat
    48301 aagtgcttgc ttgagcacgg taacgatagg ataaacgaga aagacaagat aggtaagaaa
    48361 gatgaagaaa gaggaggttg tccaaatatt tagtttttta cattccatgg ttgactcctt
    48421 ttatcaggtt ttgggaacca tctgcagaaa agatgtttaa tttttgcgta ttgattcgta
    48481 gacgaatacg attgcctttt tgtagttctt cttcaaaagt tgattcttca ctaacttgaa
    48541 tttttgaggc aaaacctgtc tcaatgaaat actccgtatt tagtccaaga tagacgctat
    48601 cgctaatagt tccttcaata tctccagatt catctttgat aaactcttcg ggacgaatgc
    48661 ttacatgaat agcttgctcc tcaacctgat caagagctgg cattcgaagg gcatagccat
    48721 ctgaaaagac gatataagcg ccgtcgctcc gtttttcaag attagtaggg ataatatttg
    48781 tgcgtccgat aaaggttgcc acaaactcat tagctggttt atgatagagt tcttttggtc
    48841 ggccgatttg ttggatcacc ccatctttca taacagcaat ttggtctgaa atagccatgg
    48901 cttcttcttg gtcgtgggtt acataaacag ttgtaattcc cacttcgtgt tggatttctc
    48961 ggatggcttg acgcatatcc aagcgaagtt tggcctccag attactaagt ggctcgtcca
    49021 tgaggagaac acttggatta accgctaagg cgcatgccaa ggtgacacgt tgttgttgtc
    49081 caccactgag tttatcgggc tttcaatccg catattgagc aatttgcatg agttcaagat
    49141 acttgttggt ctgttgaatc aattcttctt ttggaacctt cttttgcata agaccaaaag
    49201 caacgttgtc tcggacagtc aaatgtggga aaatagcgta gttttggaaa accagcccga
    49261 tattgcgttt gctgggttcc atattattga tttttgtatc atcgaagtaa aattctccat
    49321 ctttgatact gttgaaacct gcaatcatac gaagaagggt cgttttccca catcctgaag
    49381 ctccaagaag ggtaaagaga cttccttttg gaattgtaat gttcaaattc tcaataacag
    49441 ggacatcgtg gtagattttt ttggcgttaa taatttcgat ctcactcata gtgaacctct
    49501 tttactgttt agattggata tctgtaaaga cttcgttgta tttcttaacg atatctgatt
    49561 tattcttgat gacataatca taatcttcag tgagtgtttt gattttgtca attggtttca
    49621 tgttttcgct tgttttagca tttttacgaa caggacggtt agtagtggtt gtaccaagtg
    49681 tatcttgtac ttcttgagag ataataaaat cgataaattt cttggcattt tccatatttt
    49741 tagctttttt aacgatagca gcactagcag gtaggaagac ggttccttct tttggataga
    49801 ctactttaat gttagctccg tcatttaaga gtttaactgc tggatcctca taagagagac
    49861 caacagccat ttctccatca acgactgctt tatagacacc agatgaactt gaaccgattt
    49921 tatagtgtat tgaaactaga atagtacacc tctacttcta aaacattgtt agaaatcgat
    49981 ttgactgtcc tgattaattt gtcctgttct tatttcattt tactatacca tcaataagtg
    50041 tgaaaagatc ttttacataa gaccaagcct tatcatcttt gtaaccacct tgagcttgta
    50101 gcatatttgt taattgagca aaggcgctag aagagtttgc tgggtcagca gttgcgattt
    50161 ttccttttag ttcaggtttg agaaggtcgc tatatccttc gatgttcatg cctttagtta
    50221 aatcagggtg gacgattaaa acactaccat ctagtgtata aggagtagag aagccagttg
    50281 tgttttgata ttctttgata acattatcat tttcttttga aatatagttt tcaaagagtt
    50341 ctccgtgggt agcatattgt gtataagaac caccaaagat aacatcagct acaggaactt
    50401 ctttttctga ctctagtttt ttgaaaagtt ctccagtacc agcttgaatc agttctattt
    50461 tgataccata tttttcttca aaggcaggaa tagttgctcc aattaagcct tctgagtttg
    50521 gtgaataaac gactagcgaa ccaccgtctc ctttatcaga tgaactgtca tcggcagatt
    50581 cattagaaga acaagcagca taatacatcc atttcttttt catgatggat atctccgttg
    50641 tgttatttaa gtttatttta aaacaatgta agcgttttta aaacctacaa ttctattcta
    50701 tagtgtattg aatctataac agtacacttt gactgctaaa atatttctat aaattaattt
    50761 gactttcctg atagagatgt tcacatctta tttcaattca ctatattaga gtaaaattct
    50821 ctacaaaaag aagaatagcc tatttgacta ttcttccgag tgatttcaat ttctttgggg
    50881 aaatatggag atacttttta aatactttgg caaaatattt atagtctgaa aatccaactt
    50941 ggtcagagat agcgcttaaa ggggagttgg gagattcagc catcttatct atagcttgtt
    51001 tcaggcgata ttgtaagata tattcattta gagtcatggg gaagtcttct ttgataacct
    51061 tatatagatg cttgttatct gcaaatagct agagcatttc aaggaaataa actagaaata
    51121 acaattaata tggtggttca gaaatacctt ttgataatca ataagatctt caggatgaag
    51181 tgcgttgatt ccatccattt catatttccg atttaataaa cgatatttgt tttcaccaaa
    51241 ttgatgaaaa gggagtagtt gaacttggtc gatatttaat gagttaaata gagtagcgaa
    51301 tttttctgca tcctctaaac tattgttaaa attaggaata actgggattc ttaaaacgat
    51361 agttttattt tgagaaaaag cataatgaat gtttttaata atcatttgat taaaaacccc
    51421 agtcactttt ttatgtttta tagaattata atgttttagg tctgtgtaga taaaatccac
    51481 atattgaatt aaatcaataa atttttcatg atcaacaaag gcagtagttt caatggcagt
    51541 gtgtatgtga tgttctttag ctgattttaa gatggcttta gcaaattcaa actgagcaaa
    51601 tatttcacct cctgataaag ttaaacctcc accggattct tcgtaaaatt ctttgtcttt
    51661 taatacctct gtaataattt cttctacagt cttttcttca ccgactaagg tgaatttctc
    51721 tcgttgagca tctttcattt tttcaggttt cattctttga gattcaggat tagaacacca
    51781 tggacagcgc agaggacatc cttttaaaaa aacagttgta cgaatacccg ggccgtcatg
    51841 aattgaaaag tgttgaatat taaaaataat tcctttagat atttccataa gagttcctcc
    51901 tcttcataag tctatcctat cacaaaaacg aaagaaaaac aattacgaac gaaagtttaa
    51961 tttgttgttt tttgcttttt attttggtag aataaaacgg aggtgtaaaa tgaaaagatt
    52021 ggaacaaatt attaaattag tatcagaata tgaaaagatc gacgttaata cattatcgga
    52081 aaaattaaat gtatcgaaag taacgattag aaaagattta gataaattag agtcaaaagg
    52141 tttattacac agagagcatg gatatgctgt attaaatagt ggagatgact taaatgtacg
    52201 tttgtcaatt aactatgaaa ttaagagaaa aattgttcag gaagcagtaa aattggtgtc
    52261 agataatgaa acaataatga tagaatctgg atcgacctgt gctttacttg ctgaggaaat
    52321 ttgcaagcaa aaaagaaatg ttacgattgt aacaaattca ttttttatag caaattttgt
    52381 gagagcttat gattcatgtc gtattattgt tcttggtgga gagtttcaga aggattcaca
    52441 ggttactgtg ggacctttat taaaagaaat gatacagact tttcatgtgc atcaagcttt
    52501 tgttgggaca gatggttacg ataaagagat gggctttaca ggaaaagatt taatgcgcag
    52561 tgaggtagtt caatatattt cagcagcgtc ggataaagtc attgtactaa ctgactcaag
    52621 taaatttgat aaaaggggta cagtaagaag atttgcttta agtcaagtct atgaagtaat
    52681 aacagacgaa aaactttcta aacaaaatat agctacatta gaaaatgctg ggataatggt
    52741 taaggtagtt tcgtaagagg ttaaatgtat gaatcaagat aggaataaac tgctctctaa
    52801 aattgcttat ctgtattata ttgaaaactt aaatcagtca caaatagcag caaaattagg
    52861 aatttataga acctctatta gtagaatgtt aacagaagca aggaatgcag gaattgttaa
    52921 aattgaaata gagaattttg ataccaatat gtttaagttg gaaaattatg taaaagaaaa
    52981 atatggtctg gaaagtttag aaattattcc aaatgaattt gatgataatc caacaatttt
    53041 atctgaaaga atttctcaag ttgcagcagg tgtccttagg aatctaattg atgataatat
    53101 gaaaattggc ttttcttggg ggaaaagttt aagtaattta gtagatttaa ttcacagtaa
    53161 aagtgtccga aatgttcact tctatcctct agcaggtggt cctagtcaca tacacgctaa
    53221 ataccatgtg aatacactga tttatgaaat gtctagaaaa tttcatggag agtgtacatt
    53281 tatgaatgca acgattgtgc aagaaaataa attgttagca gatggtattt tgcaatcaag
    53341 atattttgaa aatttgaaaa atagttggaa agatttagat atagctgtag tcggaattgg
    53401 tgattttagc aataaaggga aacatcaatg gttagacatg cttacagagg atgactttaa
    53461 agaattgacc aaagttaaaa ctgtaggaga aatttgttgt cgattttttg attcaaaagg
    53521 taaagaagtc tatgaaaact tacaggaaag aacgatagcc atctctttgg aagatttaaa
    53581 aaatattcct caaagtttag ctgttgctta cggtgatacg aaagtatctt cgattctttc
    53641 tgtcttgcgt gctaatttag taaatcattt gattacagat aaaaatacaa ttttaaaagt
    53701 tttggaagaa gatggtgatt tgacttttag agagattcta ggtgagtgaa aatgatagac
    53761 tgatcagttt atcgtttttt ctttttagtc gattgcacat ttgtgcttat ataaacaaaa
    53821 atagtttatc tgttgttttt ggattgacaa ctttattatg tagttgtatt ctatagttac
    53881 aaaagaaaat tttaaaattt caaatgaaaa aagcttttta catagtgaaa tgaggaggaa
    53941 tttatggaaa ttattgttcc agatcaaatt atcatgggtt taattttata tgctggcgat
    54001 gcgaaacaac atatttataa agcattagat tacataaaaa atggtacatg tgaacggtgt
    54061 gaagaagaaa tccagttagc tgatgccgcc ttattagaag cccataatct acaaacaaaa
    54121 ttcttggcac aagaagcgtc tggtacaaag acagaaatta cagctctctt tgttcattca
    54181 caagatcatc tcatgactag catgacggag attaatttaa tcaaagaaat tattagtttg
    54241 agaaaagaac ttcataaaaa ataatactag agtattatca ttgttattaa catagaggag
    54301 gaaaacataa tggtgaagat tggtttgttt tgtgcagcag gtttttctac tggtatgctt
    54361 gtaaataata tgaaaattgc agcgcaatct agtggagttg aggcagaaat agaggcgttt
    54421 tctcagtcta aattagcgga ttatgcgcca aatatagatg ttgcactatt gggtccacaa
    54481 gttgcttata cattagataa atcaaaagaa atttgtgata agtgtgatgt tccgatagct
    54541 gttattccga tgatggacta tggtatgtta gatgggaaaa aagtattaga tttggcccta
    54601 tctttgatta gtgggtaaga aaaggagatt tattatgtca aagatggatg ttcagaaaat
    54661 cattgcaccg atgatgaagt ttgtgaatat gcgtggcatt atagctctaa aagatgggat
    54721 gttagcaatt ttgccattga cagtagttgg cagtttgttc ttgattatgg gacaattgcc
    54781 gttcgaagga ttaaataaga gcattgctag tgtttttgga gctaattgga cagagccgtt
    54841 tatgcaagta tattcaggaa cttttgctat tatgggtcta atttcttgtt tttcaattgc
    54901 ctattcttat gctaagaata gcggagtaga ggctttacca gctggagttc tatctgtatc
    54961 tgcattcttt attttgctaa gatcatctta tatccctaaa caaggtgagg cgattgggga
    55021 cgctattagt aaagtttggt ttggaggcca aggaattatc ggtgctatca ttataggttt
    55081 ggtagtagga agtatttata ccttctttat aaagagaaaa attgttatta agatgccaga
    55141 acaagttcca caagctattg ccaaacagtt tgaagcaatg attccagcat ttgtaatttt
    55201 cttatcttct atgattgtat atattttagc gaagtcattg actaatggcg gaacattcat
    55261 agaaatgatt tattctgcta ttcaagttcc gttgcaaggt ttaactggat ctttgtatgg
    55321 tgctattgga attgcattct ttatatcatt tttgtggtgg tttggtgttc atgggcaatc
    55381 ggtagtaaat ggagtagtga cagctctgct tttatctaat cttgatgcta ataaagctat
    55441 gttagcctct ggtaatctat cattagaaaa tggtgcacat attgttactc aacaattttt
    55501 agattcattt ttaattctat caggttcagg gattacgttt ggtcttgtag ttgccatgct
    55561 ttttgcagca aaatcaaaac aataccaagc cttaggaaaa gttgcagctt ttccagcaat
    55621 atttaacgta aatgagccag ttgtatttgg atttccgatt gtcatgaatc cagttatgtt
    55681 tgtacctttc attcttgttc ctgtacttgc agctgtgata gtatatggag ctattgcaac
    55741 aggtttcatg caaccattct caggggtaac attgccttgg agtacaccag ctattctatc
    55801 aggatttttg gtgggtggat ggcaaggtgt tgtgactcag ttattagtat tggcgatgtc
    55861 tacaatggtt tactttccat tctttaagat acaagatcgt ttagcttgcc aaaatgaaat
    55921 caaacaatct tagaggtatt tgtgtgttac tgttaaactc acacatttgt gctaaaaatt
    55981 agagagttaa aatttttcta gttaaaagct tgaaaatttc tataaaaatc ggtattatat
    56041 tttcgaaaga aataaaaata ttttcgaaag aaaggtgctt acgatggtaa atacagaagt
    56101 agcaagaaca acaatcaaga cagaatattt tggcagcctt actgaaagga tgaacaaata
    56161 tcgagaagat gttttaaata aaaaacctta tattgatgct gagagagcag ttctagcaac
    56221 acgcgcctat gaacgataca aggaacaacc taatgtccta aaacgtgcat atatgctgaa
    56281 agaaattttg gaaaatatgt ctatctatat tgaagaagaa tctatgattg cgggaaatca
    56341 agcttcttcc aataaagatg ctcctatttt tccggaatat acgctagaat ttgttctcaa
    56401 tgagttggat ctttttgaaa agcgtgatgg agatgttttc tatattacag aagaaacaaa
    56461 agaacaactt agaagtattg ctccgttttg ggaaaataat aatttacgtg ctagagctgg
    56521 tgccttatta cctgaagaag tgtctgttta tatggaaaca ggattcttcg gtatggaagg
    56581 taagatgaat tctggagatg ctcacttagc agttaactat cagaaacttt tgcaatttgg
    56641 tttaagaggt tttgaagagc gggctcgtaa agcgaaggta gctctagatt taacagatcc
    56701 agcaagtatt gataaatatc atttttacga ctctatattt atcgtaatcg atgctattaa
    56761 agtatatgca aagcgctttg ttgctcttgc taaaagttta gccgaaaatg caaatcctaa
    56821 acgtaagaaa gaattacttg agattgcaga tatttgctct agagtcccat atgaaccggc
    56881 aactactttt gcagaagcta ttcaatcagt ttggtttatt caatgtattt tacaaattga
    56941 atctaatggc cactctcttt catatggccg ttttgatcaa tatatgtatc catatatgaa
    57001 ggctgattta gaaagtggta aagaaacaga agatagcatt gttgaacgtc tgacaaatct
    57061 ttggattaag acaattacaa ttaataaggt tcgcagtcaa tcacatacat tttcttcagc
    57121 aggaagtcct ttatatcaaa atgttacaat tggtggacag actcgagata agaaggatgc
    57181 tgttaaccca ttatcttatt tggtattaaa atcagttgca caaacccatc taccgcaacc
    57241 taatctaact gtacgttacc atgcaggttt agatgctcgt ttcatgaatg agtgtattga
    57301 agtgatgaaa cttggttttg gtatgcctgc atttaataat gatgagatta ttattccttc
    57361 ttttattgca aaaggagtat tggaagatga tgcttatgat tacagtgcca ttggatgtgt
    57421 tgaaacggca gttccaggga aatggggcta tcgttgcaca ggtatgagtt atatgaactt
    57481 ccctaaggtt ctacttatca cgatgaatga tggaattgat ccggcttcgg gtaaacggtt
    57541 tgcaccaagc tttggtcatt ttaaggatat gaagaacttt tctgaattag aaaatgcttg
    57601 ggataaaaca ctaagatatt tgacacgaat gagtgttatt gttgaaaatt ctattgattt
    57661 atcattggaa cgagaagttc ctgatattct atgttcagca ttgactgatg attgtattgg
    57721 tcgtggaaaa caccttaaag aaggtggagc agtatatgat tatatatcag gattgcaagt
    57781 tggaattgca aatttgtcgg attcattagc tgcaattaaa aaattggtgt ttgaggaaga
    57841 acgtataagc ccaagtcagc tttggcatgc actggaaaca gattatgccg gagaagaagg
    57901 taaggtcatt caagaaatgt tgattcatga tgcacctaag tatggtaatg atgatgatta
    57961 tgctgacaaa ttggttactg ctgcttatga catttatgtt gatgaaattg ctaaatatcc
    58021 taatacacgt tatggaagag gtccaattgg aggaattcgt tattcaggaa catcttctat
    58081 ctcagccaac gtagggcagg gacgtggaac attagcaact ccagatggac gcaacgcggg
    58141 tacaccgtta gcagagggtt gttcaccatc acataatatg gatcaacacg gccctacatc
    58201 tgttttaaaa tctgtttcaa aattaccaac agatgaaatc gtaggtgggg ttctcttaaa
    58261 tcagaaagta aatcctcaaa cgttagccaa agaagaagat aaattaaaac taattgcttt
    58321 gttacgaaca ttctttaatc gtttacatgg gtaccatatt caatacaatg ttgtttccag
    58381 agagacgctg attgacgctc agaaacatcc tgaaaaacac agagacttaa ttgttcgtgt
    58441 tgcaggatac tctgcattct tcaatgttct ttctaaggca acccaagatg acattatagg
    58501 acgtactgag catactttgt aaaataaaga ggttcttttt atggaattta tgcttgacac
    58561 attaaattta gatgagatta aaaagtggtc tgaaattttg ccgctagctg gggtaacttc
    58621 aaatcccact attgcaaaaa gagagggttc tattaatttt tttgaacgaa tcaaagatgt
    58681 aagagaattg attggctcta caccctctat tcatgttcag gtgatttctc aagattttga
    58741 aggcatctta aaggatgctc ataaaattcg aagacaagca ggagatgata tatttatcaa
    58801 agtacctgtt actccagctg gattacgtgc aataaaggcg ctaaaaaaag agggctacca
    58861 tatcactgca acagctattt atacagttat tcagggatta ttagctatcg aagcaggagc
    58921 ggattaccta gctccatatt ataatagaat ggaaaatctg aacattgatt caaattctgt
    58981 cattcgtcaa ttagctcttg ctattgatag acagaactct cctagtaaga ttttagctgc
    59041 atcctttaaa aatgtagcac aagtaaataa tgctttagct gcaggtgcgc atgctgttac
    59101 agcaggagcg gatgtttttg aatcagcttt cgccatgcca tctatccaaa aggcggttga
    59161 tgatttttct gacgattggt ttgttattca aaatagtcgt tccatttaga tagagaggaa
    59221 atacatatga gaatttttgc tagtccttct agatatattc agggggaaaa tgccttgttt
    59281 gaaaatgcca aatcaatttt ggatttggga aattgcccta ttctattatg cgatcagttg
    59341 gtttatgata ttgttggaaa acgatttgaa gattacctac ataggtatgg tttccatatt
    59401 gttctggcgc tatttaatgg tgaagcttct gacaatgaaa tcaatcgagt tgttgccttg
    59461 gctgagaaag aaaattgtga tagtattatc ggtcttggtg ggggaaagac gattgatagc
    59521 gcaaaagcta ttgcagattt gattgaaaag cctgttatta ttgctccaac aattgcatcg
    59581 accgacgcac ctgtatctgc tttatctgtt atttatacag atgaaggtgc atttgatcat
    59641 tatctatttt attctaaaaa tccagattta gttttggttg atacaaaagt tatttcacaa
    59701 gcccctaagc gtttattagc gtctggtatt gcagatggtt tagcaacttg ggttgaggcg
    59761 cgtgcggtta tgcaggcaaa tggaaaaact atgttgggac aacagcaaac attggctgga
    59821 gttgcaattg cgaagaaatg tgaagaaacg ctgtttgcag atggtttaca ggctatggca
    59881 gcttgtgaag ctaaagtggt gacaccagca ttagaaaata ttgttgaagc taatacttta
    59941 ttgagtggtc taggttttga aagtggagga ttagctgcgg cgcatgcaat tcataatggt
    60001 tttactgcat tgacaggtga cattcatcat ttaacacatg gtgaaaaagt agcttatgga
    60061 actttagtac aactattatt ggaaaataga cctaaagaag aacttgataa gtatattgag
    60121 ttttacaaaa aaattggtat gccaacaact ctaaaagaaa tgcatttgga tcaagttgga
    60181 tatgatgatt taataaaagt tggtaaacaa gcaactatgg agggtgagac aattcatcag
    60241 atgccgttta agatttcgcc ttcagatgtt gctcaagcta ttatcgctgt agatgcctat
    60301 gtaaattcaa aataaacaat aaggactact gttttccaaa tggtagtctt ttattgatcc
    60361 ctgtattgaa ttctatagaa gattgaaata ggatgagaac aaatcgattg ggaaagtaaa
    60421 attaatttct ataaatgttt tagcaattgt ttcgtactat ttcagattca gtctactata
    60481 tgttcttcat aaatcaaaaa gcgacatagg ttgtcggcaa tcaaaaagcg acataggttg
    60541 tcggctattt attgtgaata cattaattag cattccagtt ttatcttcgg tctaaaataa
    60601 gtattttgtg ctatacgaga taagcttctt gacttactcc ttgatttact gcataacaat
    60661 gggataaaaa gtgggagata gagcaattca tagtcatcaa aattaatgag atacagtata
    60721 cagtttttcc tttaaacaca tttcaaattc cctcaaaaat ggtataatag taacatcaca
    60781 aaattggaga gagaccatga gtttttacaa tcataaagaa attgagccta agtggcaggg
    60841 ctactgggca gaacatcata catttaagac aggaacagat gcatcaaaac ctaagtttta
    60901 tgcgcttgat atgttccctt atccgtctgg agctggtctg cacgtaggac acccagaagg
    60961 ttatactgca accgatatcc tcagtcgtta caaacgtgcg caaggctaca atgtccttca
    61021 cccaatgggt tgggatgctt ttggtttgcc tgcagagcaa tacgctatgg atactggtaa
    61081 tgacccagca gaatttacag cggaaaacat tgccaacttc aaacgtcaaa ttaatgcgct
    61141 tggattttct tatgactggg atcgtgaagt caacacaaca gatccaaact actacaagtg
    61201 gactcaatgg attttcacca agctttacga aaaaggcttg gcctatgaag ctgaagtgcc
    61261 agtaaactgg gttgaggaat tgggaactgc cattgccaat gaagaagtgc ttcctgacgg
    61321 aacttctgag cgtggaggct atccagttgt ccgcaaacca atgcgccaat ggatgctcaa
    61381 aatcacggct tacgcagagc gcttgctcaa tgacttagat gaactagatt ggtcagagtc
    61441 tatcaaggat atgcaacgca actggattgg taaatcaact ggtgccaatg taactttcaa
    61501 agtaaaagga acagacaagg aatttacagt ctttactact cgtccggaca cacttttcgg
    61561 tgcgactttc actgtcttgg ctcctgaaca tgaattagta gacgctatca caagttcaga
    61621 gcaagcagaa gctgtagcag actataaaca ccaagccagc cttaagtctg acttggctcg
    61681 tacagacctt gctaaagaaa aaacaggggt ttggactggt gcttatgcca tcaaccctgt
    61741 caatggtaag gaaatgccaa tctggattgc agactatgtc cttgctagtt atggaacagg
    61801 tgcggttatg gctgtgcctg cccacgacca acgtgactgg gaatttgcca aacaatttga
    61861 ccttccaatc gtcgaagtac ttgaaggtgg aaatgtcgaa gaagctgcct acacagagga
    61921 tggcctgcat gtcaattcag acttcctaga tggactcaac aaagaagacg ctattgccaa
    61981 gattgtggct tggttggaag aaaaaggctg tggtcaggag aaggttacct accgtctccg
    62041 cgactggctc tttagccgtc aacgttactg gggtgagcca attccaatca ttcattggga
    62101 agatggaact tcaacagctg ttcctgaaac tgaattgccg cttgtcttgc ctgtaaccaa
    62161 ggatatccgt ccttcaggta ctggtgaaag tccactagct aacttgacag attggcttga
    62221 agtgactcgt gaagatggtg tcaaaggtcg tcgtgaaacc aacactatgc cacaatgggc
    62281 tggttcaagc tggtactacc tccgctatat tgatccacac aatactgaga agttggctga
    62341 tgaggacctc ctcaaacaat ggttgccagt agatatctac gtgggtggtg cagagcatgc
    62401 tgttcttcac ttgctttacg ctcgtttctg gcacaaattc ctctatgacc tcggtgttgt
    62461 tccgactaag gaaccattcc aaaaactctt taaccaaggg atgattttgg gaacaagcta
    62521 ccgtgaccac cgtggtgctc ttgtggcaac cgacaaggtt gaaaaacgtg atggttcctt
    62581 cttccatgta gaaacagggg aagagttgga gcaagcgcca gccaagatgt ctaaatcgct
    62641 caagaacgtt gttaacccag acgatgtggt ggaacaatac ggtgccgata cccttcgtgt
    62701 ttatgaaatg tttatgggac cactcgatgc ttcgattgct tggtcagaag aaggtttgga
    62761 aggaagccgt aagttccttg accgagttta ccgtttgatt acaagtaaag aaatccttgc
    62821 ggaaaacaat ggtgctcttg acaaggttta caacgaaaca gtcaaagctg ttactgagca
    62881 aattgagtct ctcaaattca acacagctat tgcccaactt atggtctttg tcaatgctgc
    62941 taacaaggaa gataagcttt atgttgacta tgccaaaggc tttattcaat tgattgcacc
    63001 atttgcacct cacttggcag aagaactctg gcaaacagtc gcagaaacag gtgagtcaat
    63061 ctcttatgta gcttggccaa cttgggacga aagtaaactg gttgaagacg aaatcgaaat
    63121 cgttgtccaa atcaaaggta aagtccgtgc caaactcatg gtcgctaaag acctatcacg
    63181 tgaagaattg caagaaattg ctctagcgga tgaaaaagtc aaagcagaaa ttgacggtaa
    63241 ggaaatcgtg aaagtgatta gtgtaccaaa taaattggtt aatattgttg taaaataacc
    63301 aatttatttg ctgatttcca acctcaaaca gtttcccaaa ctgtttgagc caactaaact
    63361 cgttaatatc gttgtgaaat aaggtaggaa tccttcagag tagaatctgg aggatttttt
    63421 gaatcttctt atgaaagtat ggtatactat gggcaactat aaagtttgaa aagtgaaaaa
    63481 aggagaaagc tatgccagta aatgaatatg gtcaaatgat tggggagtca atggaaggtt
    63541 atacaccagg tgaactgcct tctattgatt tcttagaagg gcgttatgct aggatagagg
    63601 ctctttcagt ggaaaagcat gcggaggatt tgctagctgt ttatgggcct gatacgcctc
    63661 aggagatgtg gacctacctt tttcaggagc cagtagcaga tatgggggag ctggttagcc
    63721 ttttacatca gatgttggct cgtaaggacc gtttttacta tgcaatcata gacaaggcga
    63781 ctggtaaggc tttgggatct ttttctctca tgcgcattga ccagaataac cgagtaatag
    63841 aagtcggagc agtcactttt tctccagagc taaggggtac acggatagga actgaagctc
    63901 agtatctcct agctcgctat gtttttgagg agctaaacta tcgtcgctac gagtggaaat
    63961 gcgatgcctt aaatctgcca tccagacgag ctgcggagcg tttgagcttt atttatgaag
    64021 gaaccttccg tcaggcagtg gtttataagg gacgtacgag agatacggat tggttgtcta
    64081 tgattgataa ggactggcct caagtcaaag atcgtttgga aacatggttg cgtcctgaaa
    64141 attttgataa aaatggacag cagtacaaga gcttgagaga actttaagag gtgttgacat
    64201 gattactatt aaaaagcaag aaattgtcaa gctagaggat gttttacatc tctatcaggc
    64261 tgtcggttgg acaaattata cccatcaacc agagatgctg gagcaggcct tatctcattc
    64321 attagtaatt tatctggcac ttgatggtga tgctgtggtg ggcttgattc gtttggttgg
    64381 agatggattc tcatcagtat tggttcagga tttaatcgtt ttaccaatct atcagcgtca
    64441 aggaattggt agtgccttga tgaaagaggc tttagaggat tacaaagatg cctatcaagt
    64501 ccagctggtg acagaagaga cagaaagaac cttgggcttc tatcgttcta tgggctttga
    64561 aatcttatcc acctataatt gtatagggat gacttggatg aatcgtaaaa aataacaaaa
    64621 cttgtttttt cttaagcaaa atttaaggat ggtctagtat tatatagtca ttaaataaag
    64681 acctcctaac tttatttaat aaaatcctaa acttttttca tcacaatctc ctaatgaagc
    64741 cacccaatca ggtggctttt ttgcgtggtg aggtgctggt gatagaaatt ttttgcaaaa
    64801 tagtaaaatt ttagaaaagt taagctagtt ttaagtttcg tcttgtatca tgtagttatt
    64861 aaataaagac ctcctaactt tatttaataa aatcctaaac ttttcttttt cataataatc
    64921 tcccttaact ccacccaatc aggtggagtt ttttagctct atttcaggct tttggggact
    64981 attctaaaaa taatttttcg atatttttcg gtatttttcg gattttggtc ggggaattgg
    65041 cggggacttt tttagcgaat ataactaaga aataggtctg tggtcgcttc agctagttca
    65101 aactcaattt gattgtaagt gactgttaat tgaagaactg gaactactgt aataatgatt
    65161 ttgcttgtct agtagtggcg tattaaatga gaagtgacat gtaagattgt ctcttcgttt
    65221 acgaaatcaa aatttctatg aaattgatag aatccctaac gttctcttaa tcttaaccgt
    65281 cttgtcgtac agcggttgaa gaaaatgtaa acctttgaca aaattcgtga actatgagat
    65341 aataaaaagg aattgagtac tagttctata tcataggcta gaaaagaccc caagctcacg
    65401 accaaataag cttggggtct tttttgacac tatttgtcct tgtttagcca tttatcgact
    65461 atacgaagaa cgacaccgac cacaattggt ccgatgatag ttttgagtac taattccatc
    65521 atgggctatc tcacctcctt tcgtaggcgg tgtagcagtg tcgtagaata ttataccaca
    65581 taagtgctaa acttaggagt cacccaatca ggtggctttt ttgtttgtgg cttggttttt
    65641 tgatataata gagccatgag tagaatttta gataatgaga taatggggga tgaggagtta
    65701 gtagaacgca cgctccgtcc tcagtattta cgtgaatata tcggacagga taaggtcaag
    65761 gaccagctac aaatctttat tgaagctgcc aaaatgcggg atgaagcgct ggatcatgtg
    65821 ctcttatttg ggcctccagg tctcgggaaa acgaccatgg cctttgttat tgccaacgaa
    65881 ctgggagtca atcttaagca gacgtcgggt ccagtcattg aaaaagccgg agatctggta
    65941 gctattttga atgagttaga gcctggggat gtacttttta ttgatgagat ccatcgtttg
    66001 ccaatgtcag tggaagaggt gctttatagt gctatggagg acttctacat agatattatg
    66061 attggggctg gtgagggtag tcgtagtgtt catttggagt taccaccttt taccttgatt
    66121 ggtgcgacga ctcgggctgg tatgctctcc aatccgctac gggcacgttt tgggattaca
    66181 ggccatatgg agtattatgc ccatgctgac ttgacagaaa ttgtcgagcg gacggcagat
    66241 atttttgaga tggaaatcac tcatgaggca gcatctgagt tggccctacg tagtcgtggg
    66301 acccctcgta ttgccaatcg tctcctcaag cgcgtgcgcg attttgccca gataatgggg
    66361 aatggggtaa ttgatgatat tattaccgat aaggctttga ctatgctgga tgttgaccat
    66421 gaaggtttgg actatgtgga tcaaaaaatc cttcgtacca tgattgagat gtacagtgga
    66481 ggacctgttg gtctaggaac tctttctgtg aatatcgccg aagagcgtga gacagttgaa
    66541 gatatgtatg agccttactt gattcaaaaa ggttttatca tgcggacacg gtctggacgg
    66601 gtggcgactg ctaaggcata tgagcactta ggttatgaat acagtgaaaa ataagcaaga
    66661 aatcttagag gcttttagag aaaatccaga tatgatggcc attctgacga tcatccgaga
    66721 ccttggtctg aaagactcgt ggttggcagc aggttctgtc agaaatttca tttggaatct
    66781 tttgtcagac aaatcccctt ttgatcatga aacagatata gatgtgattt tctttgatcc
    66841 agatttttct tatgaggaaa ccttattact ggagaaaaag ctgcgagagg attttcctca
    66901 gtaccagtgg gaattgaaaa atcaggtcta tatgcatcag cacagtcctc acactgcttc
    66961 ctataccagt tctcgtgatg ctatgagtaa gtatccagaa cggtgtacga cagttggact
    67021 gcgcttgaat gaagaatcag attttgaact ctatgcacct tatggtttgg aggatatttt
    67081 gaattttcaa gttcgtccaa ctcctcattt cttagaaaat gaagaccgaa tggaactcta
    67141 tcaaacacgt ttatccaaga aaaattggca ggagaaatgg aaaaatttga tttttaaaaa
    67201 tacttaagga aactttaagc tagggagtgt acactaagtt cataagttaa gaagacctta
    67261 acttaaactc ctaaaacttt ttcataataa tctccctata aaaataaagt cgcccaatca
    67321 ggcggcttat ttttttgaaa aatgggcttg gtgcctgaga ataaatagct tagtgataga
    67381 agaaaatggg gaaatatggt ataataaaac gatagatttt tgaataggaa taagatcatg
    67441 tttggatttt ttaagaaaga taaggctgtg gaagtagagg ttccgacaca ggttcctgct
    67501 catatcggca tcatcatgga tggcaatggc cgttgggcta aaaaacgtat gcaaccgcga
    67561 gtttttggac ataaggcggg catggaagca ttgcaaaccg tgaccaaggc agccaacaaa
    67621 ctgggcgtca aggttattac ggtctatgct ttttctacgg aaaactggac ccgtccagat
    67681 caggaagtca agtttatcat gaacttgcca gtagagtttt atgataatta tgtcccggaa
    67741 ctacatgcga ataatgttaa gattcaaatg attggggaga cagaccgcct gcctaagcaa
    67801 acctttgaag ctttaaccaa ggctgaggaa ttgactaaga acaacacagg attgattctt
    67861 aattttgctc ttaactatgg tggacgtgct gagattacac aggcgcttaa gttgatttcc
    67921 caggatgttt tagatgccaa aatcaatcca ggtgacatca cagaggaatt gattggtaac
    67981 tatctcttta cccagcattt gcctaaggac ttacgagacc cagacttgat tatccgtact
    68041 agtggagaat tgcgtttgag caatttcctt ccatggcagg gagcctatag tgagctttat
    68101 tttacggaca ccttatggcc tgattttgac gaagcggcct tgcaggaagc tattcttgcc
    68161 tataatcgtc gtcatcgccg atttggagga gtttaggagg aaatatgacc caggatttac
    68221 agaaaagaac cttgtttgca gggattgccc tggctatttt cctaccaatt ttaatgattg
    68281 ggggcctctt gcttcagata gcaatcggaa tcatagccat gctagccatg catgaacttt
    68341 tgaagatgag aggtctagag accatgacga tggagggcct cttgaccctc tttgcaacct
    68401 ttgcattgac cattcccttg gagaattacc tgactttttt gccagttgat gggaatgtgg
    68461 ttgcctatag tgttttgatt tcaatcatgt taggaacgac cgtttttagc aagtcttata
    68521 cgattgagga tgcggttttc cctcttgcta tgagcttcta cgtgggcttt ggatttaatg
    68581 ctttactaga tgctcgtgtt gcaggtttgg acaaggctct cttagccttg tgtatcgtct
    68641 gggcgacaga cagtggtgcc tatcttgttg ggatgaacta tgggaaacga aagttagcac
    68701 caagggtatc gcctaataaa acccttgagg gtgccttggg tggtatttta ggagcaattt
    68761 tagtaaccat tatctttatg atagttgaca gtacagttgc tcttccatat ggaatttaca
    68821 agatgtcagt ctttgctatt ttctttagca ttgctggaca atttggtgat ttactagaaa
    68881 gttcgatcaa acgtcatttt ggtgttaagg attctgggaa atttatccct ggacatggtg
    68941 gtgttttgga tcgtttcgat agtatgttgc ttgtatttcc aatcatgcac ttatttggac
    69001 tcttttaatc aaaagacgga ggaaacgcta tgctcggaat tttaaccttt attctggttt
    69061 tcgggattat tgtagtggtg cacgagttcg ggcacttcta ctttgccaag aaatcaggga
    69121 ttttagtacg tgaatttgcc atcggtatgg gacctaaaat ttttgctcac attggcaagg
    69181 atggaacggc ctataccatt cgaatcttgc ctctgggtgg ctatgtccgc atggccggtt
    69241 ggggtgatga tacaactgaa atcaagacag gaacgcctgt tagtttgaca cttgctgatg
    69301 atggtaaggt taaacgcatc aatctctcag gtaaaaaatt ggatcaaaca gccctcccta
    69361 tgcaggtgac ccagtttgat tttgaagaca agctctttat caaaggattg gttctggaag
    69421 aagaaaaaac atttgcagtg gatcacgatg caacggttgt ggaagcagat ggtactgagg
    69481 ttcggattgc acctttagat gttcaatatc aaaatgcgac tatctggggc aaactgatta
    69541 ccaattttgc aggtcctatg aacaatttta tcttaggtgt cgttgttttt tgggttttaa
    69601 tctttatgca gggtggtgtc agagatgttg ataccaatca gttccatatc atgccccaag
    69661 gtgccttggc caaggtagga gtaccagaaa cggcacaaat taccaagatt ggctcacatg
    69721 aggttagcaa ctgggaaagc ttgatccaag ctgtggaaac agaaaccaaa gataagacgg
    69781 caccgacttt ggatgtgact atttctgaaa aggggagtga caaacaagtc actgttacac
    69841 ccaaagatag tcaaggtcgt taccttctag gtgttcaacc gggggttaag tcagattttc
    69901 tatccatgtt tgtaggtggt tttacaactg ctgctgactc agctctccga attctctcag
    69961 ctctgaaaaa tctgattttc caaccagatt tgaacaagtt gggtggacct gttgctatct
    70021 ttaaggcaag tagtgatgct gctaaaaatg gaattgaaaa tatcttgtac ttcttggcaa
    70081 tgatttccat caatattggg atttttaatc ttattccgat tccagccttg gatggtggta
    70141 agattgtgct caatatccta gaagccatcc gccgcaaacc attgaaacaa gaaattgaaa
    70201 cctatgtcac cttggccgga gtggtcatca tggttgtctt gatgattgct gtgacttgga
    70261 atgacattat gcgactcttt tttagataat cgaggaatat tatgaaacaa agtaaaatgc
    70321 ctatcccaac gcttcgcgaa atgccaagcg atgctcaagt tatcagccat gctcttatgt
    70381 tgcgtgctgg ttatgttcgc caagtttcag caggtgttta ttcttatcta ccacttgcca
    70441 atcgtgtgat tgaaaaagct aaaaacatca tgcgccaaga attcgaaaag attggtgctg
    70501 ttgagatgtt ggctccagcc cttcttagtg cagaattgtg gcgtgaatca ggtcgttacg
    70561 aaacctatgg tgaagacctt tacaaactaa aaaaccgtga aaaatcagac tttatcttag
    70621 gtccaactca cgaagaaacc tttacagcta ttgtccgtga ttctgttaaa tcttacaagc
    70681 aattgccact caacctttat caaattcagc ccaagtatcg tgatgaaaaa cgcccacgta
    70741 atggacttct tcgtacacgt gagtttatca tgaaggatgc ttatagtttc cacgctaact
    70801 atgatagttt ggatagtgtt tatgatgagt acaaagcagc ctatgagcgt atttttactc
    70861 gtagtggttt agacttcaag gctattattg gtgacggtgg agccatgggt ggtaaggata
    70921 gccaagaatt tatggccatt acatctgctc gtacagacct tgaccgctgg gttgtcttgg
    70981 acaagtcagt tgcctcattt gacgaaattc ctgcagaagt gcaagaagaa atcaaggcag
    71041 aattgctcaa atggatagtc tctggtgaag ataccattgc ttactcaagt gagtctagct
    71101 atgcagctaa cttagaaatg gcaacaaacg agtacaaacc aagcaaccgt gttgtcgctg
    71161 aagaagaagt tactcgtgtt gcaacgccag atgttaaatc aatagatgaa gttgcagctt
    71221 tcctcaatgt tccagaagaa caaacgatta aaaccctctt ctacattgca gatggtgagc
    71281 ttgttgcagc ccttctagtt ggaaatgacc aactcaacga agtcaagttg aaaaaccact
    71341 taggagcaga tttctttgac gttgctagcg aagaagaagt ggcgaatgtt gttcaagcag
    71401 gatttggttc acttggacca gttggtttgc cagagaatat taaaattatt gcagatcgta
    71461 aggtgcaaga tgttcgcaat gcagttgtcg gtgctaacga agatggctac cacttgactg
    71521 gtgtgaaccc aggccgtgat tttacttcag aatatgtgga tatccgtgaa gttcgtgagg
    71581 gtgaaatttc cccagatgga caaggtgtcc ttaattttgc gcgtggtatt gagatcggtc
    71641 atattttcaa actcggaact cgctattcag caagcatggg agcagatgtc ttggatgaaa
    71701 atggtcgtgc tgtgccaatc atcatgggat gttacggtat cggtgtcagc cgtcttcttt
    71761 cagcagtgat ggagcaacac gctcgcctct ttgttaacaa aacgccaaaa ggtgaatacc
    71821 gttacgcttg gggaatcaat ttccctaaag aattggcacc atttgatgtg catttgatta
    71881 ctgttaatgt caaggatgaa gaagcgcaag ccttgacaga aaaacttgaa gcaagcttga
    71941 tgggagctgg ttatgaagtc ttgacagatg accgtaacga acgtgtcggt gttaaattta
    72001 gcgatagtga cttgattggt cttccaatcc gtatcactgt tggtaaaaaa gcggccgatg
    72061 gcattgtaga agttaagatc aaggcaactg gtgacaccat tgaggttcat gcagataacg
    72121 tgcttgaaac gcttgaaatc ctaagtaaga aataaaaact ataatcagaa gaaaaacaag
    72181 gaaaaaatgt aactagtttt taccttgttt tttctgtata atgggagaaa tgagtagata
    72241 aagaggtaaa tgtatgctaa gatttccaaa ggattttgtc tggggatcct ctacttctgg
    72301 accgcagaca gaaggacgtg tagctggtga cggtaaggga gacaatctct gggattactg
    72361 gttccaagtg gagccaaatc gttactataa tgggattggt tcagataaga catcgacttt
    72421 ttatgaaaat tgggagcggg atattgagct tttgttagag actggtcaca cagcctttcg
    72481 gacttctatt cagtggtcac ggatttttcc acaaggctgt ggaaaagtca accctcaagg
    72541 tgtggatttt tatcgtaagg tctttgaggc tattaaggct aaaggaattc gtctgttagt
    72601 caatctctat cattttgatt taccttttgc ccttcaagag gatggtgatg gttgggaaaa
    72661 taaggcgaca gtttcagcct atgaagacta tgctcgtttt tgttttgaga cttatggaga
    72721 tttagtggat caatggatta cctttaacga gcccatcgtt cctgtagaat ttggttattt
    72781 ttatgatgcc cattatccac ataaggtgga tgcagaggca gctgttaagg tagcctatca
    72841 tacacaattg gccagcagcc gggctgttaa ggcttgccat gaacttttgc ctgattccaa
    72901 gattgggatt gtcctcaact tgacaccggc ttatccacgt agccagcatc ctgctgatgt
    72961 caaggcagct cgtattgcgg ccctttttca ggcccaatct ttcttagatc catctgtctt
    73021 ggggacttat ccacaggagt tggtagaaat cttgcatgaa cacggtcttt tacctgatgc
    73081 tacagaggaa gagttggaac tcattcgtga taatacggtg gacttccttg gtgtgaacta
    73141 ctatcaacct ttgcgtgtta tggctcctcg atttgctaag catccagaga gtccactctt
    73201 accagaacat ttttacgagc attatgtgat gcctggacgt aaaatcaatt ctcaccgtgg
    73261 ttgggagatt tatgagcaag ggatttatga catcgcccaa aatatcaagg aaaattatgg
    73321 caatattgag tggatgttga ctgagaatgg tatgggtgtt gaaggggaag aaaaattccg
    73381 tcaagatgga atgattcaag atgattaccg tattgacttt gtaaaaggtc atcttcgtga
    73441 acttcaccgt gccattgaag atggtgccaa ctgtaagggc tacttgattt ggacctttat
    73501 tgactgctgg tcatggctca acagctataa aaatcgctat ggtttggtcg aattagactt
    73561 ggaaacgcaa gaacgtcgtc tgaagaaatc aggccactgg ttcaaagaat taagcgataa
    73621 taatggattt taaaaaggac tctgactgat tatcccaatc ggtcagagtt tttatgctta
    73681 caggagctta atttgaacta taccaatttt tactcttgac aagtgaaaga aacaagtata
    73741 tactgttttt actgattcta taaaagatga attagactat accaatttta aggagaaagc
    73801 acagcttgcc tgtgtcgtat atactatgtg tggaattgtt ggtgttgttg gaaacacaaa
    73861 tgcaactgat attttgattc aagggcttga aaagattgaa taccgtggct atgattctgc
    73921 gggaattttt gtcctagatg gtgctgataa ccatttggtg aaggcggttg gtcgtattgc
    73981 agaattgtct gccaagacag ctggtgttga gggaacaact ggtatcggac atactcgttg
    74041 ggctactcac ggaaaaccaa ctgaggacaa tgctcaccca caccgctctg agacagaacg
    74101 ttttgtcttg gtgcataatg gggtgattga gaactatctt gaaatcaagg aagaatacct
    74161 tgcaggtcac cacttcaagg ggcagacaga tactgaaata gccgttcatt tgattggaaa
    74221 atttgcggaa gaagaagggc tctcagttct tgaagccttc aaaaaagctc ttcatattat
    74281 ccgtggttca tatgcctttg ccttgattga ctctgaaaat ccagatgtca tctatgtagc
    74341 gaaaaacaaa tctccacttt tgattggtct tggggaaggc tacaatatgg tctgctcaga
    74401 tgctatggct atgattcgtg aaaccaacca atacatggaa attcatgacc aagagttggt
    74461 aatcgtcaag gctgatagcg tggaagttca agactatgat ggtaacagtc gtgaacgtgc
    74521 tagctatact gcggaacttg acttgtcaga tatcggtaag ggaacttatc cttactacat
    74581 gcttaaggaa attgatgagc aaccaactgt tatgcgtaaa ctcattcaag cctacacgga
    74641 tgatgctggt caagtagtga ttgatcctgc tatcattaag gctgttcaag acgcagaccg
    74701 catctacatc cttgcagctg gaacatctta ccatgcagga tttgcttcta agaaaatgtt
    74761 ggaagaattg acagatacac cagttgaact tggaatctca tctgagtggg gctacggtat
    74821 gccacttctc agcaagaaac cactcttcat ctttatcagc caatctggtg aaacagcgga
    74881 tagtcgtcaa gttttggtca aggctaatga aatgggaatt ccaagcttaa cagtgacaaa
    74941 cgttccaggt tcaaccctct cacgtgaagc caactatacc atgctccttc acgcaggtcc
    75001 tgaaattgcc gtggcatcaa ctaaagccta tacagcgcaa atcgcagccc ttgccttcct
    75061 tgcaaaagca gtcggagaag caaatggtaa tgctaaagcg caagcctttg acctggttca
    75121 tgaattgtca atcgtagctc agtctatcga atcaactctt tcagagaaag aaaccattga
    75181 agccaaggtt cgtgaacttc ttgaaacaac tcgtaacgcc ttttacatcg gacgtggtca
    75241 agattactac gtagccatgg aagcaagtct caaactcaaa gagatttctt atatccagtg
    75301 tgaaggtttt gcggcaggag aactcaagca cggaaccatt gccttgattg aagaaggaac
    75361 gcctgtcttg tctctcttgt cagatccagt tcttgccaac catactcgtg gaaatatcca
    75421 agaggtcgca gcccgtggtg ccaaagtcct cactatcgca gaagagaatg tagccaaaga
    75481 taccgacgat atcgtcctta cgaccgtaca tccatacctc tcaccaattt caatggtcgt
    75541 accaacgcaa ttagtcgctt actttgcaac cctccaccgt ggcttcgatg tggacaaacc
    75601 acgtaacctt gccaagtcag taacggtaga ataagctaaa aaagtctagt tatctaggcc
    75661 tttttcttgt gagcaaattg gttgcttgta ctcaagattc gtgttatact cttcgaaaat
    75721 ctcttcaaac cacgtcaacg tcgccttgcc gtaggtatgg ttactgactt cgtcagttct
    75781 atccacaacc tcaaaacact gttttgagca gcctgcagct agcttcctag tttgctcttt
    75841 gattttcatt gagtattaga ataatttttc aaattgaagt acagagatag ataaggagaa
    75901 tcacaatggt agaattggga atttcaacat ttggggaaat aacggagctt gaagggactg
    75961 gacaaactta cagtcatgct gaacgcattc gccagttggt ggcagagatt gagctggctg
    76021 acaaggttgg tttggatgta tatgggattg gtgagcacca tcgggcggat tttgcagtat
    76081 cagccccaga gattgttctg gccgctgggg cagtcaatac caagaaaatc cgtttgacca
    76141 gtgcagtcag cattctgtca agcatggacc cgattcgttt gttccaacag tatgccacta
    76201 tcgatgcttt gtcaaatgga cgagcggaga ttatggctgg aaggggctct ttcacggaat
    76261 ctttccctct gtttggttat gacttgaaag actacgactc tctttttgat gagaaattag
    76321 ccttgcttca gttagtcaat gaaaagacca agttagactg gcaaggtcga ttgactcaaa
    76381 cgattgctgg taaagaagtt tatcctcgtc cagttcagga caaattgccc ttgtggatag
    76441 ctacaggtgg tcatgtcgaa tcaacagtga agattgctca ggctggtcta ccgattgtat
    76501 atgctattat tggtggtaat ccacgttatt ttaaaaagtt gattcaggct tatcgtgaga
    76561 ttggaagcga agcgggtcat gctgacaaag acttgaaagt gggagcccat tcttgggggt
    76621 ggattgcgga agatggtgag caggcggtga aagattattt ccatccgact aagcaagtgg
    76681 tggatgctat ttccaaagac cgtccgcact ggcaggaatt gcgttatgag caatatttgg
    76741 agcaggtagg gccaaatggc gccatgtttg ttggcaatcc agatcaggtg gccgaaaaat
    76801 tgattcgcat gatagaggat ttaggattgg accgcttcat gcttcatcta ccgcttggtt
    76861 ctatgcctca tgaccaggtt ctgagagcta ttgaactctt cggaacacaa gttgcaccca
    76921 aagtacgagc ttattttgct atgaaagagg cttaataaaa aatcctaatc aagtttatta
    76981 ggacaacaaa tattgtacga aaattaatcc cccgagctat aatgcttggg ggatttttct
    77041 ataggagggc tagtttagtt ctctttttta ttttttagta agaaaccgag accaaggagc
    77101 gcaaggaggc tgattcctgc aaataggagt ttgttttcgt ttttgattcc tgtatttgga
    77161 agttcagctt gtctatctgg ggttgcaggt atatttttct tgctagagtt ttctaccgat
    77221 tcgttttgaa ccgcttcttt tacagatgat gcttgtgctt cttgtgctgg ttgttcagct
    77281 tgtgaatcag ctgtagcttg gctaggttta ttttccgcat cagctacttt ggcatctggt
    77341 ttagtagaat caggtctagc ttctggagct gggtcttgat gttcaggctt ggaaggggtt
    77401 gagtctggtt tctcttctgc agttgactca tggctagttc cattttgaga gactcgaaga
    77461 acagtagctg taagggcatt caatttcaag cctttttcag tccattcaag tcctttcggg
    77521 ttggcaattc cgactggtcc tgcttggttt tcatctgcca aaacttccgc atttcttaga
    77581 tgtgcaaagg cagttcccaa attaaattcg cgagcttttt catccgcatt gacaaagact
    77641 gcgtagatat cgccgtttgg agcagtgatt tggtagccaa tcactacatc ctctttttcc
    77701 acaccatttt ggcctgggac agtgatgagg tggacacggt ctttgatatc ttggagactc
    77761 ttaagtcgga aggcatctgt agattgacga agggcaatca aacctttcat atagtcacgg
    77821 ctcttgacat tttcaggata agctttacca tctgtagcct tagtccagtc aaacttgttg
    77881 actgcgtcgc tagaatcgta agaatcatgg atgaagtaag gatagtcaaa tgggttgccg
    77941 tccttatcac gcaacaagtg agatttgttt ggaaccttat cctctgctac tggagtcttg
    78001 taggctgggt cacggaattg tttagtacgt ccatattcct gaccggagtg gataaatgga
    78061 gttccttgag ctgtcaagac catgagattt ccaagtcgta aacgacggtg gatttcagca
    78121 tagttctcag ccttgcttgg gtcttttttg atagactggg caatgatgtc aaagagggtc
    78181 aagttatcat gggctgcgat gtattggatg acatctccag ggctgtcagc ttcaaagtta
    78241 gttggttgag caatgagatt tttaaagatg gtgttgacat cacgcttgcc acctgtgata
    78301 aaggcaggtt gaccttcgtt tggataacca gatttgaggt tgttacggat gtcatctgaa
    78361 aagacagcga cagtatcggt atgtttcatc caatcttggt cagcagcttt agtaggcatg
    78421 ttttcatcac cggcataggt tctccaacct tcgcctaaca tgattagatt tggattgagg
    78481 gcgcgtgcag ccttgtaagc ttcttcgata gaagcggcgt catggtctcc catcatatcg
    78541 aagcggaagc catccacttt gtaggtatca actaggtatt tgatagagtc aactaggagg
    78601 cgtttggtca tatggtgggt tgtccccaag cgtccaccac caaagctagt tcgaggtgtg
    78661 ccatcggcat ccataaagtg gtagtagttt ggctctaggt cttcaaagat atcgactttg
    78721 gctgtgtggt tataaacgac atctaggata gctcccatac cacgtttgtg gatttcgttg
    78781 atgaggtttt taaattctgc gattcgtttt tctggattct taggatcgct tgagtacata
    78841 ccagtcaagg agaagtagtt ttgagggtca tatccccagt tgtagttgct gttgcttgaa
    78901 gcatagtcag acaagcgttc atggtttttc aattcattga caaagtagta agacaagact
    78961 ggaaggagct ggatatgggt tacacccaag tctttgagat agtctagttt ttcaatgaag
    79021 gcttcaaaag tcccaaatgg tttggtcaag tcttttgcaa tggcaggatc tgaagtgaag
    79081 tcacgcacat gagcttcgta gataacggcg tcttcacgag tcttgaaatt gtgaatctta
    79141 ccataagtca agtcttgagg tccgagttta gctggatcta caaaggcggc tttagccact
    79201 ttatgggcat cgtcaatctt ggcatcgttg ctattccaag cagcaagaga tttagcgtaa
    79261 ggatcgagtg caagaacagt tttaccttga cgctcgattt ggtattgata atagtagcca
    79321 gtgaaatctg tgattccgag tttgtttgtg ctgtctagag tttgtttcca agttcctctt
    79381 tccccttttt cgagagcgac agttccaact actttgtcag ggtcattctt gtcgtagaca
    79441 acaacagaaa ccttatcagc acttggtgac caaagggtca aatcaacttg ttttccttct
    79501 tcttttaggt cagctcccag tttgccatca tagctgtatg tctcatcttt caggcgccag
    79561 cttgttttgg tagtgaattg gtcggaattg tagctaacag tataaggatg ttttgtgtca
    79621 gagaaatctc cgctgtaggt cactttctta ccagcttcat cgattgcaac atcggtaata
    79681 gttaccttgt ttcctaggtg attagtgatg ttggagtgtt tgaggatatc ttctttttta
    79741 gcaccgacaa gtgttgaaaa gctactttca atgctagaag tgcctacgtg ttgggctcct
    79801 gtcatacgga tatcatggac atagtatgga tttgtgtaaa tcgattcatc atcgtctttt
    79861 aggaaaattt ggctatgatt tttcaaatct gtgaacttat aattttcttt acggattttc
    79921 acgtcgtctc cttgtttgct ctcatctagt aataaaaatc caaattctct tgcggcttca
    79981 ttaagaggaa tgtcgatata gcggccatat ttgcctgtag ccgtaaagtc tgttccgtca
    80041 ggccattgag cgctacttgg atttttcaca tctccccagt accagagaga tttcttgtca
    80101 tagttgccat ctgtgcggta gtagttgacg cgaacagttc ctgcaggctg tggctcgtaa
    80161 gagaaaacct tgtaatcttg gtctaaccaa gcttcgttca tttttggaac tagtttttct
    80221 acagatttat cgccggttag attttttcca gctgtattgt tgatgaggaa gctaattttc
    80281 ttggcttgtt ctccctttaa tttgacatct aggtaatagc cgtagtcatc tttcttggca
    80341 tccttgaagg acaaagctcc gtttggccag ttttcagatg gtttttcaac atcgtcccaa
    80401 gtccatagtc cttgagcatc cttgttttct tcaggaagtt ttttgacatg gatacggaag
    80461 tagttatctt cgatgggctc ttctgcctta gtttcagttg ttactggact agtagaagta
    80521 gttggctcac ttgaacgatc ttgtccagtt tgtggtgctg gatcggctgg gcttgcagca
    80581 ggagttgttg gctctgttgc aggtttttct tctgttttct ctagggaagc gtttgcattt
    80641 ccaagtgaag aaatatcact tttgttctta ccagagccag ctgctgtatc agtaagaggt
    80701 tgggcaaggg tggttgtatt tctgttgttg ggttcgttag tggttggtgt actttcgtcg
    80761 gatgagatag ttggtgtagc catggcaagc aagacaaggc ttgcgccgat aaggacagaa
    80821 ccagtcccat ttttgaggga acggatgctg tagaccattt ttttctcagt gtgagatggt
    80881 gtttttctca taatgattct ccaatcaata aatttctata tcagtatagc atgtagtaaa
    80941 acaatatgca agcgttttct ttgatttgtg aaaaaaattc ttacttttga gaagttttct
    81001 gtactatttt atatatcagt ataaatgacg gagataaaaa tgtcacataa gccaagccgt
    81061 attattagga agatgatgtg ttcccagcta tttttattca gaaattgatc tctaacatta
    81121 ccaataaaaa agaaaaatat cttgacaaac aagggaaaat tttgttacaa taatagacgg
    81181 tactttttac ttttggtctc tcaagagtgt acagggacgt gctgacaaat gttgcaaaag
    81241 tacacacaga tgatatctgt caccaagtgt atcatcacca aaaataaaaa aacacaggag
    81301 aatgtagatg cctacaatta accaattggt tcgcaaaccg cgtaaatcaa aagtagaaaa
    81361 atctaaatca ccagctttga acgttggtta caatagtcat aaaaaagttc aaacaaacgt
    81421 ttcttcacca caaaaacgtg gtgttgcaac tcgtgttgga acaatgacac ctaaaaaacc
    81481 taactcagcc cttcgtaaat tcgctcgtgt acgtttgagc aaccttatcg aagttactgc
    81541 ctacatccca ggtatcggac acaacttgca agagcacagc gtggtgcttc ttcgcggtgg
    81601 acgtgtaaaa gaccttccag gggtacgtta ccatatcgtc cgtggtgcac ttgatactgc
    81661 aggtgttaac gatcgtaaac aaggtcgttc taaatacggt actaaacgtc caaaagcata
    81721 aggaaagggg ataaagagaa atgagtcgta aaaatagagc tccaaaacgt gacgtattgc
    81781 cagatccgct atacaattca caactagtta ctcgtcttat caaccgcgtt atgcttgatg
    81841 gtaaacgtgg tactgctgct tcaatcgttt acggtgcttt tgagcaaatc aaagaagcta
    81901 ctggcaacga tgcacttgaa gtatttgaaa cagctatgga aaacatcatg cctgtacttg
    81961 aagtacgtgc acgtcgtgtt ggtggttcta actaccaagt cccagttgaa gttcgtccag
    82021 aacgtcgtac aacacttgga cttcgttggt tggtaacaat cgctcgtctt cgtggtgaac
    82081 acacaatgca agaccgtctt gcaaaagaaa tcttggatgc tgctaacaac actggtgcag
    82141 ctgttaagaa acgtgaagat actcaccgta tggctgaagc taaccgtgca ttcgcacact
    82201 tccgttggta agataggatg cgaaagcgtt aagaaagtcc cagagaaaat agggaatcga
    82261 agcaggttgc ggttgcaacc aatgagattc atctttttct ccagactttt agcttgagct
    82321 caactaaatc atgatgctag gcacggtaag gatgcaaggt gaaaatagga aactgacgca
    82381 gtattcaacg aatacaagga gttttatctt tttcacgcag catcccgttc cagctcacat
    82441 cggctaacta actttagccc gggttcaaat tagctaaatc gattagtatt agctataact
    82501 cagcttacca tctcgtaagt tgaaaccaac aatagcatga aaacattgag aacgggtagg
    82561 tcctgcctat ccgtttttat taaaatcgtg ttataataga atagaaatca aaaataaata
    82621 ggagaaacaa acctcatggc acgcgaattt tcacttgaaa aaactcgtaa tatcggtatc
    82681 atggctcacg tcgatgccgg taaaacaaca actactgagc gtattcttta ctacactggt
    82741 aaaatccaca aaatcggtga aactcacgaa ggtgcgtcac aaatggactg gatggagcaa
    82801 gagcaagaac gtggtatcac gatcacatct gctgcgacaa cagctcaatg gaacaaccac
    82861 cgcgtaaaca tcatcgacac accaggacac gtggacttca caatcgaagt acaacgttct
    82921 cttcgtgtat tggatggtgc ggttaccgtt cttgactcac aatcaggtgt tgaacctcaa
    82981 actgaaacag tttggcgtca agcaactgag tacggagttc cacgtatcgt atttgccaac
    83041 aaaatggaca aaatcggtgc tgacttcctt tactctgtaa gcacacttca cgatcgtctt
    83101 caagcaaatg cacacccaat ccaattgcca atcggttctg aagatgactt ccgtggtatc
    83161 attgacttga tcaagatgaa agctgaaatc tatactaacg accttggtac ggatatcctt
    83221 gaagaagaca tcccagctga ataccttgac caagctcaag aataccgtga aaaattgatt
    83281 gaagcagttg ctgaaactga cgaagaattg atgatgaaat acctcgaagg tgaagaaatc
    83341 actaacgaag aattgaaagc tggtatccgt aaagcgacta tcaacgttga attcttccca
    83401 gtattgtgtg gttcagcctt caaaaacaaa ggtgttcaat tgatgcttga tgcggttatc
    83461 gactaccttc caagtccact tgacatccca gcaatcaaag gtattaaccc agatacagac
    83521 gctgaagaaa ctcgtccagc atctgacgaa gagccatttg cagctcttgc cttcaagatc
    83581 atgactgacc cattcgtagg tcgtttgaca ttcttccgtg tttactcagg tgttcttcaa
    83641 tcaggttcat acgtattgaa tacttctaaa ggtaaacgtg aacgtatcgg acgtatcctt
    83701 caaatgcacg ctaacagccg tcaagaaatc gacactgttt actcaggtga tatcgctgct
    83761 gccgttggtt tgaaagatac tacaactggt gactcattga cagatgaaaa atctaaaatc
    83821 atccttgagt caatcaacgt tccagaacca gttatccaat tgatggttga gccaaaatct
    83881 aaagctgacc aagacaagat gggtatcgcc cttcaaaaat tggctgaaga agatccaaca
    83941 ttccgcgttg aaacaaacgt tgaaactggt gaaacagtta tctcaggtat gggtgaactt
    84001 caccttgacg tccttgttga tcgtatgcgt cgtgagttca aagttgaagc gaacgtaggt
    84061 gcgcctcaag tatcttaccg tgaaacattc cgcgcttcta ctcaagcacg tggattcttc
    84121 aaacgtcagt ctggtggtaa aggtcaattc ggtgatgtgt ggattgaatt tactccaaac
    84181 gaagaaggta aaggattcga attcgaaaac gcaatcgtcg gtggtgtggt tcctcgtgaa
    84241 tttatcccag cggttgaaaa aggtttggta gaatctatgg ctaacggtgt tcttgcaggt
    84301 tacccaatgg ttgacgttaa agctaagctt tatgatggtt catatcacga tgtcgactca
    84361 tctgaaactg ccttcaagat tgcggcttca ctttccctta aagaagctgc taaatcagca
    84421 caaccagcta tccttgaacc aatgatgctt gtaacaatca ctgttccaga agaaaacctt
    84481 ggtgatgtta tgggtcacgt aactgctcgt cgtggacgtg tagatggtat ggaagcacac
    84541 ggtaacagcc aaatcgttcg tgcttacgtt ccacttgctg aaatgttcgg ttacgcaaca
    84601 gttcttcgtt ctgcatctca aggacgtggt acattcatga tggtatttga ccactacgaa
    84661 gatgtaccta agtcagtaca agaagaaatt attaagaaaa ataaaggtga agactaatcc
    84721 gtcctcactc tagaaggaag tcacttagtg gcttcctttt gtctttagaa aatacctcta
    84781 aatatggtaa aatagtagaa gaataatgtg aggaaaatga atgtcaaata gttttgaaat
    84841 tttgatgaat caattgggga tgcctgctga aatgagacag gctcctgctt tagcacaggc
    84901 caatattgag cgagttgtgg ttcataaaat tagtaaggta tgggagtttc atttcgtatt
    84961 ttctaatatt ttaccgattg aaatcttttt agaattaaag aaaggtttga gcgaagaatt
    85021 ttctaagaca ggcaataaag ctgtttttga aattaaggct cggtctcaag aattttcaaa
    85081 tcagctcttg cagtcctact atagggaggt tttctctgaa ggtccatgtg ctagtcaagg
    85141 ttttaagtcc ctttatcaaa atttgcaagt tcgtgctgag ggtaatcagc tatttattga
    85201 aggatctgaa gcgattgata aggaacattt taagaagaat catcttccta atttagccaa
    85261 acaacttgaa aagtttggtt ttccaacttt taactgtcaa gtcgagaaga atgatgtctt
    85321 gacccaagag caggaagagg cctttcatgc tgaaaatgag cagattgttc aagctgccaa
    85381 tgaggaagcg ctccgtgcta tggaacaact ggagcagatg gcacctcctc cagcggaaga
    85441 gaaaccagtc tttgattttc aagcgaaaaa agctgcagct aaacccaagc tggataaggc
    85501 ggagattact cctatgatcg aagtgacgac agaggaaaat cgtctggtat ttgaaggggt
    85561 tgtttttgat gtggagcaaa aagtgactag aacaggtcgt gttttaatca actttaaaat
    85621 gacggactat acttcaagtt tttctatgca aaagtgggtt aaaaacgagg aagaggccca
    85681 gaagtttgac ctcatcaaga agaattcttg gctccgagtt cgagggaatg tggagatgaa
    85741 taatttcaca cgcgatttga ctatgaacgt acaggatctg caggaagttg ttcactatga
    85801 gcggaaggat ttgatgccag aaggtgagcg tcgggttgag tttcatgctc atactaacat
    85861 gtcgactatg gatgctttgc cagaggtcga agagattgtt gcaacagctg ctaagtgggg
    85921 acacaaggcg gttgctatca cggaccatgg gaatgtccag tcctttccac atggctataa
    85981 ggcggctaag aaagcgggaa tccagctgat ctatggaatg gaagccaata tcgtggagga
    86041 ccgtgtccct atcgtctata acgaagtgga gatggacttg tcagaagcaa cctacgtggt
    86101 ctttgacgtg gaaacgacgg gactttcagc tatctataat gacttgattc aggttgcggc
    86161 ctctaagatg tacaagggga atgttattgc tgaatttgat gaatttatca atcctgggca
    86221 tcccttgtca gcttttacta cagagttaac tggaattaca gatgatcatg tcaaaaatgc
    86281 caaaccacta gaacaagttt tgcaagaatt ccaagaattt tgcaaggata cggtcctagt
    86341 tgcccacaat gctacctttg acgttggctt tatgaatgct aattatgagc gtcatggtct
    86401 tccaaagatt agtcagccag ttattgatac gctggagttt gctagaaacc tctatcctga
    86461 gtataaacgc catggtttgg ggcctttgac caagcgtttt ggtgtggcct tggaacatca
    86521 tcacatggcc aactacgatg cggaagcgac tggtcgtctg cttttcatct ttatcaaaga
    86581 ggtagcagaa aaacatggtg tgaccgattt agctagactc aacattgatc taatcagtcc
    86641 agattcttac aaaaaagctc ggatcaagca tgcgaccatc tatgtcaaga atcaggtagg
    86701 tctaaaaaat atctttaagc tggtttcctt gtctaatacc aagtattttg aaggagtgcc
    86761 acggattccg agaacggttc tagatgccca tcgagagggc ttgattttag gttcagcctg
    86821 ttcagagggt gaagtttttg acgtggtcgt ttctcaaggt gtggatgcgg cggttgaggt
    86881 ggccaagtat tatgacttta tcgaggtcat gccaccggct atctatgcgc ccttgattgc
    86941 caaagagcag gtcaaggata tggaggaact ccagaccatt atcaagagtt tgatagaggt
    87001 tggagatcgc cttggcaagc ctgttctggc tacgggaaat gttcactata tcgaaccgga
    87061 agaagagatt tatcgtgaaa ttatcgtccg tagtttggga cagggtgcga tgattaaccg
    87121 aactatcggt catggtgaac atgcccaacc agcaccactt ccaaaggctc attttcgaac
    87181 gactaatgag atgttggatg aatttgcctt tttgggagag gaactggctc gtaaactggt
    87241 tattgaaaac accaatgcct tggcagaaat atttgaaccc gttgaagtcg ttaagggtga
    87301 cttgtatacg cctttcatcg acaaggctga agaaacagtt gctgagttga cctataagaa
    87361 agcttttgag atttatggaa atccgctgcc agatattgtt gatttgcgga ttgaaaaaga
    87421 attaacatcc atactgggga atggatttgc tgtgatttat ctggcatcgc agatgctggt
    87481 gcaacgttct aatgaacggg gttatttggt tggttctcgt gggtctgtcg gatctagttt
    87541 cgttgcgacc atgattggga ttacggaagt caatcctctc tctcctcact atgtctgtgg
    87601 tcagtgtcag tacagtgagt ttatcacaga tggttcgtac ggttcaggat ttgatatgcc
    87661 ccataaggac tgtccaaact gtggtcacaa actcagtaaa aacggacagg atattccgtt
    87721 tgagaccttc cttggttttg atggggataa ggttcctgat attgacttga acttctcggg
    87781 agaagatcag cctagcgccc acttggatgt gcgtgatatc tttggtgaag aatatgcctt
    87841 ccgtgcggga acggttggta cggtagctgc caagactgcc tatggatttg tcaagggtta
    87901 cgagcgagat tatggtaagt tttatcgtga tgcagaagta gaacgcctcg ctcaaggagc
    87961 ggcgggtgtc aagcggacaa caggccaaca cccgggggga atcgttgtta ttccgaacta
    88021 catggatgtc tacgatttta cgcctgtcca gtatccagca gatgatgtca cggctgaatg
    88081 gcagaccact cactttaact tccacgatat cgatgagaac gtcctcaaac tcgatgtact
    88141 gggacatgat gatccgacca tgattcgaaa acttcaggat ttgtctggta ttgaccctaa
    88201 taaaattcct atggatgacg aaggcgtgat ggcactcttt tctgggactg atgtgctagg
    88261 ggtaacacct gaacaaattg gaacgcctac gggtatgttg gggattccag agtttggaac
    88321 aaatttcgta cgtggaatgg tagacgaaac ccatccgaca acctttgcgg aattgcttca
    88381 gctgtctggt ctgtcccacg gtactgacgt ttggttgggg aatgctcagg atctgattaa
    88441 gcaaggaata gcggacctat cgactgttat cggttgtcgg gacgacatca tggtttacct
    88501 catgcatgcg ggtctggaac ctaagatggc ctttaccatt atggaacggg tacgtaaggg
    88561 tttgtggcta aagatttcag aagaggagag aaatggctat atcgaagcaa tgaaggctaa
    88621 taaggtgcca gagtggtata tcgaatcctg tgggaaaatt aagtacatgt tccctaaggc
    88681 ccatgcggca gcctacgtta tgatggcctt gcgtgtagct tacttcaagg ttcaccatcc
    88741 tatttattac tactgtgctt acttctccat tcgtgctaag gcttttgata tcaagaccat
    88801 gggtgcgggc ttggaggtca tcaagcgcag aatggaagaa atctctgaaa aacggaagaa
    88861 caatgaagcc tctaatgtgg aaatcgatct ctatacaact cttgagattg tcaatgagat
    88921 gtgggaacga ggtttcaagt ttggtaaatt agatctctac tgtagtcagg cgacagagtt
    88981 cctcatcgac ggggataccc ttatcccacc atttgtagca atggatggtc tgggagagaa
    89041 cgttgccaag caactggtgc gggcgcgtga agagggagaa tttctctcta aaacagaact
    89101 acgcaagcgt ggtggactct catcaacctt ggttgaaaag atggatgaga tgggtattct
    89161 tggaaatatg ccagaggata accagttgag tttgtttgat gagttgtttt aaaaaattgc
    89221 ttaataatct attaaaagag gctaacgtat atccaataga tttacattag ctttcttttt
    89281 tgttaaaata gtctatggaa agagggtgag agtatgtcaa agatgagtat aagcatccgt
    89341 ctggatagtg aggttaagga gcaggcccaa caggtgttta gtaatctggg aatggatatg
    89401 acaacagcta ttaatatttt ccttcgtcag gcaattcaat atcagggact accttttgat
    89461 gttagactag acgaaaatcg gaagttgctc caagcgttaa cggatttaga ccaaaatcgt
    89521 aatatgagcc agtcttttga atcagtctca gatttgatgg aggacttacg tgcttaagat
    89581 tcgttatcat aaacagttta aaaaagattt taagttggct atgaagcgtg gtttgaaggc
    89641 agaattatta gaagaagttt tgaattttct ggttcaagaa aaagaacatc ctgccagata
    89701 tcgtgatcat tcattgacgg catccaagca ttttcaagga gttcgtgaat gccataccca
    89761 gccagattgg cttttggttt ataaagtaga caagtcggaa ttgattttaa atttgctgag
    89821 gacaggcagt cacagtgatt tattttaatc tattttaagg gggttctcat gaaactaaga
    89881 atatttgcgg aagataagcc ggctaagaag gtatttgaat atcaattaga acttgctgat
    89941 cgtacaattc ttctatcgac agcactcttg tcaggtgcta ttgctttagc aggaatcttt
    90001 tctgctttga gagaaaaata aaaatagaaa agagaaaaca gaatggtttt accaaatttt
    90061 aaagaaaatc tagaaaaata tgcgaaattg ttggttgcga acggaattaa cgtgcaacct
    90121 ggtcacactt tggctctctc tattgatgtg gagcaacgtg aattggcaca tctaatcgtg
    90181 aaagaagctt atgccttggg tgcgcatgag gtcatcgttc agtggacaga tgatgtgatt
    90241 aaccgtgaga aattcctcca tgccccgatg gagcgtttgg acaatgtgcc agaatacaag
    90301 attgctgaga tgaactatct cttggagaat aaggctagcc gtcttggagt tcgttcatct
    90361 gatccaggtg ccttgaacgg agtggacgct gacaagcttt cagcttctgc taaagctatg
    90421 ggacttgcca tgaagcctat gcgtatcgca actcaatcta acaaggttag ctggactgta
    90481 gcagctgcag caggacttga gtgggctaag aaagtcttcc caaatgctgc gagcgacgaa
    90541 gaagcagttg atttcctttg ggaccaaatt ttcaaaactt gccgtgtcta cgaagcagat
    90601 cctgttaagg cctgggaaga gcatgcagct atcttgaaga gcaaggccga tatgcttaat
    90661 aaggagcaat tttcagccct tcactacaca gcgccaggaa cagatttaac acttggtttg
    90721 ccaaagaacc atgtttggga atcagctggt gctgtcaatg cacagggcga aggattcttg
    90781 ccaaatatgc cgacagaaga ggtcttcaca gcacctgact tccgtcgtgc agatggttat
    90841 gtcacttcta caaaaccgct tagctacaac ggaaatatta ttgaaggcat taaggtgacc
    90901 tttaaggatg gacaaatcgt agatatcact gctgagaagg gtgatcaggt tatgaaagac
    90961 cttgtctttg aaaatgcggg tgcgcgtgcc ttgggtgaat gtgccttggt accagatcca
    91021 agtccaattt ctcagtcagg cattaccttc tttaacaccc ttttcgatga aaatgcgtca
    91081 aaccacttgg ctatcggtgc agcctatgcg actagcgttg ttgatggagc ggagatgagc
    91141 gaagaggagc ttgaagctgc agggcttaac cgttcagatg ttcacgtaga ctttatgatt
    91201 ggttctaacc aaatggatat cgatggtatt cgtgaggatg gaacgcgggt acctcttttc
    91261 cgtaatggga attgggcaaa ttaaggagat aatatgttag gaagtatgtt cgttggtctc
    91321 ctagtgggat ttttagcagg tgctatgacc aatcgtggag agcgaatggg atgttttgga
    91381 aaaatgtttc tcggttggat cggagccttt ctaggtcact tgctctttgg aacttggggg
    91441 ccagttttat caggaacagc tattatccca gctgttttag gtgccatgat tgtcttagct
    91501 attttttgga gacgaggaag ttaatttcct aaatctgata ctcaatgaaa atcaaagagc
    91561 aaactaggaa actagccgca ggttgctcaa agcactgctt tgaggttgca gatagaactg
    91621 acgaagtcag taacatatat gcggcaaggc gacgttgacg cggtttgaag agatttttga
    91681 agagtatgaa acgaaaagga ggttggtcat tgtactagcc tccttttgat atgatataat
    91741 agttctatga gattagataa atttttagtt gcctgtgcgg tgggaagtcg gactgaggtc
    91801 aaaaacttgc tcaaggctgg gcgcgtgact gtaaatggta aaaaagaaaa atcagctaaa
    91861 ttgcagattg atgaaaaaat agatgagatt cgctttgatg ggcaagtgtt ggagtatgaa
    91921 gagtttgtct actacatgat gaacaagccc aaaggagtta tctcagcgac tgaggatccc
    91981 aagcacagaa ccgttctgga cttgttggat gacttggcgc ggagtaagga agtttttcca
    92041 gtaggacgct tggatattga cacgcatggt cttttgctct tgaccaataa tggtcagctg
    92101 gctcatgttc ttctttctcc caagcgtcat gtggacaaga cttatcaggc tcaggtcaag
    92161 ggaattatga cccaagaaga tgtggagaca tttatcaagg gcattccgct caaagacttt
    92221 acctgtcagc ccgctagact ggagattctt tccacagatg cagaaaagaa tcagagccaa
    92281 atccgtgtga ccattgcaga agggaagttt catcagatca agcgtatggt gggctactgt
    92341 ggcaaggaag tggtggactt gcaacgattg actatgggaa ctttagtatt agatgagaac
    92401 ctggaacgag gggaatggcg tcgcttgacc aaggaagaat tagaaattct ccgcgctaat
    92461 attatttaat ttagtttaat actcaatgaa aatcaaagag caaactagga aactagccgc
    92521 aggctgtact tgagtacggc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt
    92581 ataaattcga aaaaggtgag ggagaatgtc cttacctttt atgtttttta gttgcttcct
    92641 ttgtgaaaag agttataata gactgtagaa taaaaggagg aatctatgaa cgcgattcaa
    92701 gaatcattta ctgataaact atttgccaac tatgaagcaa atgtaaaata ccaagcgatt
    92761 gaaaatgctg ccagccacaa cggaattttt gcagctctgg aacgtcgcca aagccatgta
    92821 gacaacacac ctgttttctc attggattta accaaggaca aggtcactaa ccagaaagcg
    92881 tctggtcgtt gctggatgtt tgcggctctc aacaccttcc gccacaaact catctcgcaa
    92941 tacaaattgg agaactttga gttgtcacaa gcccacactt tcttctggga taagtatgag
    93001 aaatcaaact ggttcttgga gcaagtcatt gcgacttcag accaagaatt gactagccgc
    93061 aaggttagct tcttactcca aacacctcaa caagatggtg gtcaatggga tatggtcgtt
    93121 tccctctttg aaaaatacgg tgtcgtgcct aagtcagttt atcctgagtc tgtttcatct
    93181 agcagcagtc gtgagctaaa tgcgatcctt aataaattgc ttcgtcaaga tgctcaaatc
    93241 ttgcgtgatt tgcttgtttc tggtgcagat caagtgactg ttcaaactaa gaaagaagac
    93301 ctcttgcaag aaatctttaa ctttcttgct atgtcattag gacttccacc acgcaagttt
    93361 gactttgctt atcgcgataa agataacaac tacaaaagtg aaaaaggaat cacaccacaa
    93421 gagttctaca agaaatatgt caatcttcct ttagaagact acgtttctgt tatcaatgct
    93481 ccaactgctg ataaacctta cggaaaatct tacacagttg agatgttggg gaatgtggtt
    93541 ggtagccgtg cagttcgcta catcaacgtt ccaatggagc gcttgaaaga attggcgatt
    93601 gcccaaatgc aagcaggtga gactgtttgg tttggttctg atgtcggcca gctcagcaac
    93661 cgtaaggctg gcatccttgc gacagatgtt tatgactttg aatcaagcat ggacattaaa
    93721 cttactcaag acaaggctgg acgtttggac tatagtgaaa gcttgatgac ccacgccatg
    93781 gtcttgacag gtgttgactt ggacgaaaat ggtaaatcaa ccaagtggaa ggttgaaaac
    93841 tcatggggag acaaggtcgg tacagatggt tactttgttg cctcagacgc ttggatggac
    93901 gaatacacat accaaatcgt tgttcgtaag gaattgctga cagcagaaga acaagctgcc
    93961 tatggagcag aaccaatcgt acttgcacca tgggatccaa tgggagcctt ggctgaataa
    94021 aagcatagaa aaaaggaatc agattttaga acctggttcc tttttagttg cttgattaca
    94081 tgatgtgaag aacatgtgcc acaataccca ctgcgaagag ggcaaggata atagtgattg
    94141 gagatacttt tttcttaagt aagtacatgc aaagtaaagt aaggagtagt cctgataatc
    94201 caggaatcaa catatccaag ttttgttgga aagtagtaac tttttcagga gtttgagaca
    94261 atccttgtcc tacttgtgcg aatgcttctt ggataccttt agacccttct ggcaatttat
    94321 cccaatggat ataagccttt tcatctagtt gaactttaga aacatcgaaa gcaaatttaa
    94381 tatttaccca gcgttgaaca aggacagcaa gaatgaacat cccaaggata gaagctcctt
    94441 tagtgatatc ttgaaggata ccaccagaca tatctttagt gatttctgat ccagccttgt
    94501 atccaatctc ttgaacatac cacaagaatg acatacgaat caagttccat gcaacaaaga
    94561 agaggagtgg acccaagata ttgccagtaa gggcaagtga agcaccgaga gatccaagga
    94621 ttgggcgtac tgtaaaccag aatactgggt caccgatacc agcaagaggt cccatcatac
    94681 cgattttaac cccttggata gcagcgtcat cgatttccac accgttagca cgttcttctt
    94741 caagcgcaag agtaaccccc atgactggag cagctacgta tggatgagtg ttgaagaact
    94801 caaggtgacg ctcaagagca gcgatttgat cttctttttt agtatagagt tttttgatag
    94861 ctggaatgag tgtataagcc cagcccaagt tttgcatccg ttcaaagttc caagaccctt
    94921 gtaagaaggt tgaacgccac caaacttttt tacgatctga tttagttaat tgaagttttt
    94981 cagtcatgat gttttcagtc ctttcttatc ttagtagtct tctaggatat cgccgattgg
    95041 gtcgttagaa gttgcggctc ctccgccacc atttccacca gttttagaaa ggtgaaggta
    95101 gataagagcg atagcaacac cgatagcacc gaatccgatt agagtaatat ctgacacagc
    95161 agcgagaacg aaaccaagag cgaagaatgg ccatacttca cgagttgcca tcatgttgat
    95221 aaccatggcg taaccaacgg caacgaccat accaccaccg atagccatac catctttgag
    95281 ccagtctggc atggcactaa ggatactttg tacagtttca gttggtacca taaggagaag
    95341 agctgcagga agcgcgatac gaagtccttg gaaaagtagc gcaatgaaat gcgcacgctc
    95401 cacagcgccg aagtcacctt ttttagcggc agcatctgca gtatgaacca aaccaactga
    95461 aattgtacga acaatcattg tcaagaaaag tccagctacg gcaagaggga tagcaaccgc
    95521 ttgggcaaca ccgataccag tcttggtaaa gtcaccacca agaaccatga taatggcagc
    95581 agcgacagaa gcaagtgcag catcaggagc gatagcagca ccgatatttg accaaccaag
    95641 ggcaatcatt tgaagcgatc caccgaggat aatccctgct tccaagtgac ctgttacaag
    95701 cccaataagg gtacaggcta caagtggttg gtgaaattgg aactggtcga ggatgccttc
    95761 aagacctgca aagaaggcta caacgactac taaaaccata gaaataatag acatgtttaa
    95821 aatcctttca taaataatgg cttatttgac attggctttg ttaatcaagt caaacaaatc
    95881 ttttttagaa tcatttggta ctttacggac atcaaattca acacccaagt cacgcatttt
    95941 ttcaaatgta gcaacatctt ctttgtccat agacaaaacg gtattgacca atgttttacc
    96001 tgttgagtga gccatagaac caacgttaag agtcttgatt ggcacgccgc cttcgatggc
    96061 acgaagggca tcttgaggtg tttcaaacaa gataagggca tgtgtttctc caaaacgtgg
    96121 gtcttttgaa atctcaatca gtttttgaat tggaaccacg ttagccttga cattacctgg
    96181 agctgcttgt ttaatcaatt ctttacgaag gtcgtcttta gccacgttat ctgaagcaac
    96241 gatgatacga tttgcttttg aatctggagt ccaagcagtt gcaacctgac cgtgaagtag
    96301 acgtgtgtca agacgggcaa gattgatttt caatttaccg tctccgataa cagttccttc
    96361 tgggatagca gtttgggcaa ctggagcagc tgcagcgctt gcaacttctt caactggatt
    96421 tagctcttct ggaagagctt tgatgccatc tttggcttct ttaatgatat tagcagcgac
    96481 tttttctaca cctgcagcag cgtccatgag gcgctctgtg taggcttgaa tcaacatcgg
    96541 taagttaagt cctgtgatga tggcaaactt acgctcagga ttttctccca tcacgcgact
    96601 agcttggtta aatggagaac cactccaaag gtcagccaaa actagaacct catcttctgc
    96661 gtcaaatgca gcaacagcgt tattaaactt agcgtataga tcatcaggac cttcatttgg
    96721 cataaaggtc acaacttgaa ccttttcttg ttcaccaaag atcatagatc ctgactgatg
    96781 aatacccgca gcaaattcgc cgtggctcgc aataatgatt ccgatactca ttattgtcat
    96841 tcctcctttt ttgttttagt tttcatttaa gaaaacttta agactgttta agtataaacc
    96901 gttttcataa aaaaagcaac tatttatcat aaaaaattaa aaaattttta tttttatatg
    96961 ttgatatgtt gagtttttga ggagtaatct tgaattctta tttaaaattt aatataaaaa
    97021 agttggaaga agcttccaac ttttaaaata ggtttctatt agattagtgg gtgaagtcga
    97081 gtaccatacg tccttggatt tggccttttt ccatttcgtc gaaaatggca acagcatctt
    97141 ctactggacg tttttgaaca actgggacta ccagaccttc tgcaccaaat tggaaggctt
    97201 cttctaagtc tttacgagtt ccgacaagag aaccgatgac ttggattcca tcgaggactg
    97261 ttttaacgat gctgagttcc atcgtttcag aaggaagacc aacagcgacg acgcgaccac
    97321 cagcacgaat ggagtcaaca gcctggttga aggcaacttt agacacagca gttacgacag
    97381 ctgaatgagc tcctccatca gttttttctt taatgagtcc agctacatct tcaacttcga
    97441 ggccgttaat cacaatgtca gcgcctactt cttttgcaag ggcaagtttg tcattgttga
    97501 tatcgactgc gataacatga gcattgaata cttttttagc gtattgaaca gcgaggttac
    97561 caagtccacc agcaccgtaa agaacaaccc attggcctgg ttcaactttt gcttctttga
    97621 tagctttata ggttgttact ccagcacatg tgatagaaga agcttgggct ggatcaagtc
    97681 cgtcaggaac tttgacagca tagtcagcag ttacgataca ttgttcagcc ataccaccgt
    97741 ctactgagta gccagcattt ttcactgtac ggcaaagggt ttcgcgacca gttgtacagt
    97801 attcgcaagt gccacatcct tcaaagaacc aagcaacgct gacgcggtca ccgactttaa
    97861 ggcttttcac atctggagca atctctttaa cgataccgat accttcgtgc ccaagaacac
    97921 gtcctgggac ttgaccaaag tcaccatgag caacgtggag gtcggtgtgg caaacgccac
    97981 agtattcaac ttctacaagt gcttccccag tttcaagtgg acggagtact ttttcttcaa
    98041 tagcaacacc agtgctttct ggatttacaa caacagcttt catagctatc ctccttgata
    98101 ttgaccgaga acagggacaa cgggactgga ttgatttttt gtcaacagag tcgagtgtga
    98161 cgagctctct tgtatttata tgtgaagtat atcacaaaag aaagcctttt ccaaggtttt
    98221 ggagacaaaa agtagaacaa tcgattaact ggttgatgag actgtgaaaa gagcacaaag
    98281 accagcttgc aagctggtca tactcttcga aaatctcttc aaaccacgtc agcttcatct
    98341 acaacctcaa agcagtgctt tgagcaacct acggctagct tcctagtttg ctctttgatt
    98401 ctcattgagt atcagtatag gttataagaa taagtcttgt agggttttgg caaccccatc
    98461 ttggtcgttg gtaagggaaa tttgctcatc tgcataagga agtagctctg gattggcatt
    98521 tttcatggca taacccttcc cagcaaaagc gagcatttcg gtatcattgt gttcatctcc
    98581 aaaggcaatc aaatcttttt tgtcacgatt cattatcttg agcaagtagt ccaaagcaaa
    98641 ggccttgttg acaccttttg gggtacattc aaggatattg agcggacctc cccaggtatt
    98701 gatagaaagt tgatgctggt agaaggcgtt catgtctttt gccaaggcat atttgtcact
    98761 ggctctggtc tgcaagagga tacagttagg gtccttggtc accaattcag gctggaattg
    98821 atcttcaggc tggaaagctt ctacaccaaa tagtttggga ttggcaatct cttcattggg
    98881 atttgtaatg tagaattttt tacgatattc tccagcgata aaatcggctt gaatgtcctc
    98941 tgaacgttga accatatcta gcagatattt tttgtctaca gtcaaacact tttcaaaatc
    99001 ccaaacttgg tctggtaaat gagtaaggga tccgttgaag ttaatcatag gagtgtctaa
    99061 gcccagttca cggtaaaaat cttttgacat acggtaaggg cgacctgtcg taataataac
    99121 ctgatggcct ttttcagcaa cttttttgat ggtttttttg gtaaagtcag aaatttgact
    99181 gtctgagttg agcagggttc catccaggtc aactgcaata atttttttcg tcatatggac
    99241 ctttctagtg tgttttcaga taagatgtct tctattataa cagaaagcag gcagaaaagc
    99301 agattccaaa caaaaaatga aattggatta atttcttaaa caaatcaaac aaagacattg
    99361 aaaaagtgaa tgataaatga tataattcta ttattgttcg taaaaattaa aaggagattg
    99421 atgatggaca aattatttaa actaaaagag aacggtacag acgttcgtac agaggttctc
    99481 gctggtttaa caactttctt tgcaatgagc tatattctct ttgtaaaccc acaaatactt
    99541 tcacaaacag gaatgcctgc tcagggtgtc ttcctagcga cgattattgg tgcagtagcg
    99601 ggtaccttga tgatggcttt ttatgctaac ttaccttatg cccaagcgcc aggtatggga
    99661 ctcaatgcct tctttacctt tacagttgta ttcgggcttg gttattcttg gcaagaagcc
    99721 ctagctatgg tcttcatctg tgggattatt tcattgatta ttaccttgac aaaggttcgt
    99781 aaaatgatca ttgaatcgat tcccaatgct cttcgctcag ctatttcagc tggtatcggt
    99841 gtcttccttg cctatgtagg gattaagaat gctggacttt tgaaattcac gattgatcca
    99901 ggcaactata ctgttgtagg agaaggggct gacaaagctc aagcaacgat tgcagcaaac
    99961 tcttcagcag ttccaggatt ggtcagcttt aataatccag ctgttttagt ggctcttgca
   100021 ggacttgcca ttactatctt ctttgtcatc aaagggatta aagggggaat tattctctct
   100081 atcttgacaa caactgttct tgctattgca gttggtttgg ttgatttgtc tagtatcgat
   100141 tttgctaata accatgttgg tgcagctttt gaagatttga agacaatctt tggtgcagct
   100201 cttggttcag aaggtttagg agctttggtt tcagatacag ctcgcttgcc tgaaactctg
   100261 atggccattc ttgccttctc attgacagat atttttgaca caattggtac cttgatcggt
   100321 acaggtgaaa aagttggtat tgtagcgaca aatggtgaaa atcaccaatc agccaaattg
   100381 gataaggctc tttactctga tttgattgga acgacagtcg gtgccattgc aggtacttca
   100441 aacgtaacga cttatgttga gtctgctgct ggtatcggtg caggtggacg tactggtttg
   100501 acagccttgg ttgtagctat ctgttttgcg atttcaagct tctttagccc acttctagcg
   100561 atcgtaccaa cagcggctac agctccaatc ttgattatcg ttgggattat gatgcttggt
   100621 agcttgaaaa atatccattg ggatgatatg tctgaagcag ttcctgcctt cttcacatct
   100681 atctttatgg gattcagcta ctctatcact caagggattg cagttggttt cttgacttac
   100741 actttgacta agcttgttaa aggtcaagtt aaagatgttc atgccatgat ttggattttg
   100801 gatgccttgt ttatccttaa ctacattagc atggccttat aatagaatga cccaggggga
   100861 tttcccccct tttttaatac aaaggagata ggtgatgaaa gagaaaaata tgtggaaaga
   100921 attgttgaat cgtgcaggct ggattttggt ctttttactt gccgtccttt tatatcaggt
   100981 tcccctagtg gttacctcta ttttgacttt aaaagaagta gccctgctac agtcagggct
   101041 gatggttgct ggcctttcaa ttgtggttct ggctctattt attatgggag ctcgtaaaac
   101101 caagttagct agttttaatt tttctttttt tagagctaaa gatttggcac gtttgggttt
   101161 gagttattta gttattgtcg ggtcaaatat acttggttct atcttgttgc aactgtcaaa
   101221 tgagacgaca acagctaacc agtctcagat taatgatatg gttcaaaata gttcgttgat
   101281 ttccagtttc ttcttgctag ccttgcttgc tccgatttgt gaggaaatct tgtgtcgtgg
   101341 gattgttcct aaaaagattt tccgaggcaa ggagaacttg ggatttgtag tcggtacgat
   101401 tgtgtttgct ttattgcatc aaccaagtaa tttaccttct ttattgattt atggaggtat
   101461 gtcgacagtt ctatcttgga cggcctacaa gacccaacgt ttggaaatgt cgatcttgct
   101521 tcacatgatt gttaatggga ttgctttctg tttgttggct cttgtggtga ttatgagtcg
   101581 gacattagga atttctgttt aaaagctttt atgtagaaac cgacctcttt ctactaggga
   101641 aagatgaatg caatcgtgtc catctttttc tttttatggt aaaatagaaa aataataaga
   101701 tgaaaagcct tgagggagtg accgatatgt caagtaaagc caatcatgca aaaacagcta
   101761 tttgcggaat tatcaatgta accccagact ccttttcgga cggtggtcaa ttttttgctc
   101821 ttgagcaggc actccagcag gctcgtaaat tgatagcaga aggagccagt atgctcgata
   101881 tcggcggaga atcgactcgg ccgggcagta gctatgttga gatagaagag gaaatccagc
   101941 gtgttgttcc agtgatcaaa gcgattcgca aggaaagtga tgtcctcatc tctattgata
   102001 cttggaagag tcaagtagca gaggctgctt tggctgctgg tgccgatcta gtcaatgata
   102061 tcactggtct tatgggtgat gagaaaatgg ctcatgtggt agctgaagcg agagcgcaag
   102121 tggtcatcat gtttaaccca gttatggctc ggcctcagca tcctagttcg cttatcttcc
   102181 ctcattttgg ttttggtcaa acctttacag aaaaagagtt agcggacttt gaaacattgc
   102241 caatcgaaga attgatggag gctttctttg aacgagcact agcgagagcg gcagaagctg
   102301 gtattgcacc agaaaatatc ctgttggatc caggaattgg ctttggtctg accaagaaag
   102361 aaaatctgct tcttttacgg gacctggata aactacatca gaagggctat ccaatctttc
   102421 tcggagtgtc gcgcaagcga tttgtcatca atatcctaga ggagaatggt tttgaagtca
   102481 atcctgagac agagcttggt ttccgaaatc gggacacggc ttcggctcat gtaactagta
   102541 tcgctgcgag acagggtgta gaagtggtgc gcgtgcatga cgtagctagt cacaggatgg
   102601 cagttgaaat tgcctctgcc attcgtctgg ctgatgaagc ggaaaattta gatttaaaac
   102661 aatataaata agatgaaaga aattgaaaac aatcagtgga ttgctaacta ccggacggat
   102721 caaccgcatt ttggcttgga acgaatggtg gaactgttag ctttgcgtgg caatccccat
   102781 ctcaaactca aggtcctcca tatcggaggg actaacggca agggctcgac tattgctttt
   102841 ttgaaaaaga tgctagaaaa gctagggttg agagttggcg tgtttagctc gccctatctc
   102901 attcattaca cagaccagat tagcatcaat ggggaatcga tctcagaagc gaggctagaa
   102961 gctctcatgg cagactatca gtctttgctg gagggagaag cggtcgccaa tttacagggc
   103021 acaaccgagt ttgagattat cacagccctg gcctatgact actttgcctc agagcaagta
   103081 gatgtggcca tcatggaagt tggcatgggt ggacttttgg atagtaccaa tgtctgtcag
   103141 cccattttga caggaattac aactattggc ttggatcatg tggccctact tggtgacacc
   103201 ttggagtcca tagcagagca gaaggcaggt attatcaaac aagggatgcc cttggtaaca
   103261 gggcgtattg ctccagaagc cttagctgtg attgaccgca ttgcggaaga gaaagatgcg
   103321 ccgagacttg cctacgggac agattatcag gttcgtcatc aagaaagtgt ggtgacaggg
   103381 gaagtctttg actatacaag tgctgtcaga caaggttgct tccagactag cctgcttggt
   103441 ttgtaccaaa tagagaatgc tgggatggcc atagctttac ttgatacttt ttgtcaagaa
   103501 gatggtcgag agctagcaag caatgacttt cttggtcaag ccttggaaga aacaagttgg
   103561 ccagggcgtt tggaaatcgt gtcaagagat cccttgatga ttttggatgg agcccacaat
   103621 ccccatgcta tcaaggcctt gttggtaacc ttgcaagaac gttttgcgga tcatcataag
   103681 gaaatcctct tcacttgtat caaaaccaaa gccttggagg atatgttgga cttgctggga
   103741 gccatgccag ataccgagct tactctaaca cattttgcgg atagtcgggc gacggatgaa
   103801 agcgtgctga aagaggcagc taaggctaga aatctcagct accaagattg gcatgatttt
   103861 ctagagcaga atttgacaga taaaaaagaa gagaaacaaa cagttaggat tgtcacaggt
   103921 tccttgtatt tcttgagcca agtgagggcc tatctgatgg agaggaagaa cgagaatgga
   103981 tacacaaaag attgaagcag ctgtaaaaat gattatcgag gctgtaggag agaacgctaa
   104041 tcgcgagggc ttgcaggaaa cacctgctcg tgtagcccgt atgtatcaag agattttttc
   104101 aggtcttggt caaacagcag aggaacattt gtcaaaatcc tttgaaatta ttgacgataa
   104161 tatggtggta gaaaaggata tctttttcca taccatgtgt gaacaccact tcttgccatt
   104221 ttatggtaga gcgcacattg cctacattcc agatggtcgt gtggcaggct tgtctaagct
   104281 agcccgtacg gttgaagttt attcgaaaaa accacaaatt caagaacgtt tgaatatcga
   104341 agtggccgat gccttgatgg actatctagg tgctaaagga gcctttgttg tcattgaggc
   104401 ggaacatatg tgtatgagta tgcgtggtgt tagaaaacca ggcactgcaa ccttgacgac
   104461 agtagctcgt ggtctatttg aaacagataa ggatctccgt gaccaagctt atcgtttaat
   104521 ggggctataa aaagaatccg cttcaagcgg atttttctag aaaggaatca ttatggatca
   104581 actgcagatt aaggatttgg aaatgtttgc ctatcatggt ctttttccta gtgagaaaga
   104641 attggggcag aaatttgtcg tttcagccat cctatcctat gatatgacca aggcagctac
   104701 agacttggat ttaacagcct ctgtccatta cggagaattg tgtcagcagt ggacgacttg
   104761 gtttcaggaa acgagtgaag atttgattga aacggtagcc tataaactgg tggaacgtac
   104821 ctttgagtct tatcctcttg tccaagaaat gaagttggaa ctgaaaaaac cttgggcacc
   104881 ggtgcatttg tcactagata cttgctcggt aaccattcat cgccgcaagc aacgagcctt
   104941 tatcgcccta ggaagcaata tgggagataa acaagcaaac ttgaagcaag ccattgacaa
   105001 actgcgagct cgtggcatcc atattctcaa agagtccagt gtcttagcga cggagccttg
   105061 gggtggagtg gagcaggata gctttgccaa tcaagtggtt gaggtggaaa cctggctacc
   105121 agcacaagac ttgttagaaa ccttgttagc cattgagtca gagctgggac gggtgagaga
   105181 agtgcattgg ggacctcgtt tgattgattt ggacttgctc tttgtggagg accagatcct
   105241 ttatacagac gacctcatat tgcctcatcc ttacatagcg gaacgccttt ttgtccttga
   105301 gtccttacag gaaattgcgc ctcattttat ccatccgata ttaaaacaac cgatccgcaa
   105361 cttgtatgat gctttgaaaa aatagaaaaa ctctagtttt cagtcacttg caactgaagg
   105421 ctagagtttt tatactcttc gaaaatcaaa ttcaaaccac gtcagcgtcg ccttaccgta
   105481 ctcaagtaca gcttgcggtt agcttcctag tttgctcttt gattttcatt gagtattaaa
   105541 ataggtcatt ttcttctggg aggaggatag tttctctacc gtccatgtct aaaaccagta
   105601 ctcttggggg ataacgaggg tcgaaaggat ggttaaagtc aaaatcaatg gctgtaggga
   105661 ggtgttgact tgaaaagtgg aaggtaatct ttccttggtt attaagcaat tgaaactcga
   105721 gttcttcttc caattcaaag acatttttta agaaatgatc gatgatatac caaaaagagt
   105781 caatgatgtc atcgggcaag ctggtaacaa tgccaaaact agcagaccgc atgtgggtat
   105841 tggtaaaagc catatctctg tcccctttct tttcccttat catacagcaa ataggattaa
   105901 aaatcaagaa aaggtgattt tttgaaaagg attttaacta cagggaaaaa gaaggaaaaa
   105961 aattcccaaa aatctaccga agttaatagg taaattccca aattaacttg attatataac
   106021 tttcagttac tttgagaagt taccgaaaaa tatttttcat atctattgac ttttaggggt
   106081 aaaatttggt atgatagtag gcggtattgt ttaccccatt tgaaaggccc cggaaccttc
   106141 caaatacttt tcgatgggaa ggaacaccca tcaccgtaaa caaaaatcga actatatata
   106201 ggagaaatca tgaacaaaac aacatttatg gctaaaccag gccaagttga acgtaaatgg
   106261 tacgtagttg acgcaactga tgtaccactt ggacgtcttt ctgcagtagt tgctagcgta
   106321 cttcgcggaa aaaacaaacc aacatttaca ccacacactg atacaggtga cttcgtgatt
   106381 gttatcaatg ctgaaaaagt taaattgact ggtaaaaaag caactgataa aatctactac
   106441 actcactcaa accacccagg tggattgaaa caaatctctg caggtgaact tcgttctaaa
   106501 aatgcagtac gtttgattga gaaatcagtt aaaggtatgc ttccacacaa tacacttgga
   106561 cgcgctcaag gtatgaagtt gaaagtattt gttggagctg agcacactca cgctgcacaa
   106621 caaccagaag ttcttgacat ttcagaactt atctaaggaa aggaacaata aagtatgtca
   106681 caagcacaat atgcaggtac tggacgtcgt aaaaacgctg ttgcacgcgt tcgccttgtt
   106741 ccaggaactg gtaaaatcac tgttaacaaa aaagatgttg aagagtacat cccacacgct
   106801 gaccttcgtc ttgtcatcaa ccaaccattc gcagttactt caactgtagg ttcatacgac
   106861 gttttcgtta acgttgtagg tggtggatac gctggtcaat caggagctat ccgtcacggt
   106921 atcgctcgtg cccttcttca agtagaccca gacttccgcg attcattgaa acgcgcagga
   106981 cttcttacac gtgactcacg taaagttgaa cgtaagaaac caggtcttaa gaaagctcgt
   107041 aaagcatcac aatttagtaa acgttaattc gaaagaatta ctatacttat acagagcacc
   107101 tttcggggtg ttcttttttt atactttctt actaaattgg tgcaattgac acagttgttg
   107161 cgactttagt cgcttacaaa tgtggctgca acctgacaag gtcagttgcc tcaaaacgtt
   107221 aatcaatacg attatatcaa tgtttcaaag cactcaaaag tttaccttat ttttatagta
   107281 aggtgaaata agaataggac aaaccgagga taatcaaatc gaattctaac aatgttttag
   107341 aagtagaggt gtactattct agtttcaatc tact
//
LOCUS       DAYYYC010000002        68665 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.002, whole genome shotgun sequence.
ACCESSION   DAYYYC010000002 DAYYYC010000000
VERSION     DAYYYC010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68665
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.002"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(166..1914)
                     /locus_tag="ACHBV5_000118"
     CDS             complement(166..1914)
                     /locus_tag="ACHBV5_000118"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9965996.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLVIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(1916..3640)
                     /locus_tag="ACHBV5_000119"
     CDS             complement(1916..3640)
                     /locus_tag="ACHBV5_000119"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9965997.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLSKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQKLWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFIILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(3698..4636)
                     /gene="msrB"
                     /locus_tag="ACHBV5_000120"
     CDS             complement(3698..4636)
                     /gene="msrB"
                     /locus_tag="ACHBV5_000120"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFM9965998.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4703..4855)
                     /locus_tag="ACHBV5_000121"
     CDS             complement(4703..4855)
                     /locus_tag="ACHBV5_000121"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9965999.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTEEVSSRHCFEVADRTDEVS
                     NIYTVR"
     gene            complement(4931..5800)
                     /gene="thrB"
                     /locus_tag="ACHBV5_000122"
     CDS             complement(4931..5800)
                     /gene="thrB"
                     /locus_tag="ACHBV5_000122"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HFM9966000.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAAAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(5802..7088)
                     /locus_tag="ACHBV5_000123"
     CDS             complement(5802..7088)
                     /locus_tag="ACHBV5_000123"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HFM9966001.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7239..7976)
                     /gene="mecA"
                     /locus_tag="ACHBV5_000124"
     CDS             complement(7239..7976)
                     /gene="mecA"
                     /locus_tag="ACHBV5_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFM9966002.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8176..9210)
                     /locus_tag="ACHBV5_000125"
     CDS             complement(8176..9210)
                     /locus_tag="ACHBV5_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFM9966003.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9239..10675)
                     /locus_tag="ACHBV5_000126"
     CDS             complement(9239..10675)
                     /locus_tag="ACHBV5_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HFM9966004.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNNVSLLSTLLFLL
                     VSSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVM
                     VSILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRL
                     FERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSF
                     IAANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAM
                     GVLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPV
                     LDYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYI
                     MELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSE
                     SFFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(10691..11677)
                     /locus_tag="ACHBV5_000127"
     CDS             complement(10691..11677)
                     /locus_tag="ACHBV5_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFM9966005.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11679..12782)
                     /locus_tag="ACHBV5_000128"
     CDS             complement(11679..12782)
                     /locus_tag="ACHBV5_000128"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFM9966006.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12772..13617)
                     /locus_tag="ACHBV5_000129"
     CDS             complement(12772..13617)
                     /locus_tag="ACHBV5_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HFM9966007.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13896..15170)
                     /gene="psr"
                     /locus_tag="ACHBV5_000130"
     CDS             complement(13896..15170)
                     /gene="psr"
                     /locus_tag="ACHBV5_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HFM9966008.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15167..16015)
                     /gene="pheA"
                     /locus_tag="ACHBV5_000131"
     CDS             complement(15167..16015)
                     /gene="pheA"
                     /locus_tag="ACHBV5_000131"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFM9966009.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEGVTIPLQSQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(16012..16488)
                     /locus_tag="ACHBV5_000132"
     CDS             complement(16012..16488)
                     /locus_tag="ACHBV5_000132"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFM9966010.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16481..17764)
                     /gene="aroA"
                     /locus_tag="ACHBV5_000133"
     CDS             complement(16481..17764)
                     /gene="aroA"
                     /locus_tag="ACHBV5_000133"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFM9966011.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSASFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17856..18194)
                     /locus_tag="ACHBV5_000134"
     CDS             complement(17856..18194)
                     /locus_tag="ACHBV5_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HFM9966012.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18205..19308)
                     /locus_tag="ACHBV5_000135"
     CDS             complement(18205..19308)
                     /locus_tag="ACHBV5_000135"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFM9966013.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLESIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            complement(19318..20484)
                     /gene="aroC"
                     /locus_tag="ACHBV5_000136"
     CDS             complement(19318..20484)
                     /gene="aroC"
                     /locus_tag="ACHBV5_000136"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFM9966014.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20494..21561)
                     /gene="aroB"
                     /locus_tag="ACHBV5_000137"
     CDS             complement(20494..21561)
                     /gene="aroB"
                     /locus_tag="ACHBV5_000137"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFM9966015.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(21580..22434)
                     /locus_tag="ACHBV5_000138"
     CDS             complement(21580..22434)
                     /locus_tag="ACHBV5_000138"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFM9966016.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEAHLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(22424..23101)
                     /gene="aroD"
                     /locus_tag="ACHBV5_000139"
     CDS             complement(22424..23101)
                     /gene="aroD"
                     /locus_tag="ACHBV5_000139"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFM9966017.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMKILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23098..24261)
                     /locus_tag="ACHBV5_000140"
     CDS             complement(23098..24261)
                     /locus_tag="ACHBV5_000140"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HFM9966018.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24946..26580)
                     /locus_tag="ACHBV5_000141"
     CDS             complement(24946..26580)
                     /locus_tag="ACHBV5_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966019.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMIICFSNIAIHFPFEEIPIYFSLMIAILLVIAFSTSLTAFYNVFYESK
                     DLISYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVDPFSTEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(26561..27310)
                     /locus_tag="ACHBV5_000142"
     CDS             complement(26561..27310)
                     /locus_tag="ACHBV5_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966020.1"
                     /translation="MIEFQNVSKLYGDKKALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPDQSLESIYLSLAGRKEEVADASQGH"
     gene            27489..28943
                     /locus_tag="ACHBV5_000143"
     CDS             27489..28943
                     /locus_tag="ACHBV5_000143"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HFM9966021.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(29033..31651)
                     /gene="alaS"
                     /locus_tag="ACHBV5_000144"
     CDS             complement(29033..31651)
                     /gene="alaS"
                     /locus_tag="ACHBV5_000144"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFM9966022.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(31673..32158)
                     /locus_tag="ACHBV5_000145"
     CDS             complement(31673..32158)
                     /locus_tag="ACHBV5_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HFM9966023.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32433..32672)
                     /locus_tag="ACHBV5_000146"
     CDS             complement(32433..32672)
                     /locus_tag="ACHBV5_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966024.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLNDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(32941..34011)
                     /locus_tag="ACHBV5_000147"
     CDS             complement(32941..34011)
                     /locus_tag="ACHBV5_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM9966025.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGSEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(34008..34781)
                     /locus_tag="ACHBV5_000148"
     CDS             complement(34008..34781)
                     /locus_tag="ACHBV5_000148"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9966026.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34778..35584)
                     /locus_tag="ACHBV5_000149"
     CDS             complement(34778..35584)
                     /locus_tag="ACHBV5_000149"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9966027.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35565..36722)
                     /locus_tag="ACHBV5_000150"
     CDS             complement(35565..36722)
                     /locus_tag="ACHBV5_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966028.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36883..37788)
                     /gene="murB"
                     /locus_tag="ACHBV5_000151"
     CDS             complement(36883..37788)
                     /gene="murB"
                     /locus_tag="ACHBV5_000151"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFM9966029.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(37900..38652)
                     /locus_tag="ACHBV5_000152"
                     /pseudo
     CDS             complement(37900..38652)
                     /locus_tag="ACHBV5_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(38662..39393)
                     /gene="budA"
                     /locus_tag="ACHBV5_000153"
     CDS             complement(38662..39393)
                     /gene="budA"
                     /locus_tag="ACHBV5_000153"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HFM9966030.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            complement(39877..40398)
                     /locus_tag="ACHBV5_000154"
     CDS             complement(39877..40398)
                     /locus_tag="ACHBV5_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcin A-M57"
                     /protein_id="HFM9966031.1"
                     /translation="MKFKKIVTSALVVLSLFSIMSPSIASVRVFADDVTTTEVSEIST
                     QEQKQIDDVANVLEQMFRNGVNEKNFTEYVYKNFSQKDIALAENELETNINNPYDRVP
                     WDEMGGCIAGKIRDEFFAMINVSLIVKYAQKKAWSELAKVVLRFVKANGLKTNIYIIA
                     GQLAIWAVQCGLE"
     gene            40829..42100
                     /locus_tag="ACHBV5_000155"
     CDS             40829..42100
                     /locus_tag="ACHBV5_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFM9966032.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(42120..42935)
                     /locus_tag="ACHBV5_000156"
     CDS             complement(42120..42935)
                     /locus_tag="ACHBV5_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM9966033.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(43092..43745)
                     /gene="phoU"
                     /locus_tag="ACHBV5_000157"
     CDS             complement(43092..43745)
                     /gene="phoU"
                     /locus_tag="ACHBV5_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFM9966034.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(43757..44515)
                     /gene="pstB"
                     /locus_tag="ACHBV5_000158"
     CDS             complement(43757..44515)
                     /gene="pstB"
                     /locus_tag="ACHBV5_000158"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFM9966035.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLNPQHKETEDYITGKFG"
     gene            complement(44528..45331)
                     /gene="pstB"
                     /locus_tag="ACHBV5_000159"
     CDS             complement(44528..45331)
                     /gene="pstB"
                     /locus_tag="ACHBV5_000159"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFM9966036.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(45342..46226)
                     /gene="pstA"
                     /locus_tag="ACHBV5_000160"
     CDS             complement(45342..46226)
                     /gene="pstA"
                     /locus_tag="ACHBV5_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFM9966037.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(46216..47133)
                     /gene="pstC"
                     /locus_tag="ACHBV5_000161"
     CDS             complement(46216..47133)
                     /gene="pstC"
                     /locus_tag="ACHBV5_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFM9966038.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(47133..48011)
                     /gene="pstS"
                     /locus_tag="ACHBV5_000162"
     CDS             complement(47133..48011)
                     /gene="pstS"
                     /locus_tag="ACHBV5_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFM9966039.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(48585..49889)
                     /locus_tag="ACHBV5_000163"
     CDS             complement(48585..49889)
                     /locus_tag="ACHBV5_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFM9966040.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(49890..50663)
                     /locus_tag="ACHBV5_000164"
     CDS             complement(49890..50663)
                     /locus_tag="ACHBV5_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFM9966041.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(50653..50931)
                     /locus_tag="ACHBV5_000165"
     CDS             complement(50653..50931)
                     /locus_tag="ACHBV5_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFM9966042.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(50931..51332)
                     /locus_tag="ACHBV5_000166"
     CDS             complement(50931..51332)
                     /locus_tag="ACHBV5_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFM9966043.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(51542..52159)
                     /locus_tag="ACHBV5_000167"
     CDS             complement(51542..52159)
                     /locus_tag="ACHBV5_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFM9966044.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(52149..52922)
                     /locus_tag="ACHBV5_000168"
     CDS             complement(52149..52922)
                     /locus_tag="ACHBV5_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFM9966045.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(52933..53670)
                     /locus_tag="ACHBV5_000169"
     CDS             complement(52933..53670)
                     /locus_tag="ACHBV5_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFM9966046.1"
                     /translation="MCLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(53675..54805)
                     /gene="hemW"
                     /locus_tag="ACHBV5_000170"
     CDS             complement(53675..54805)
                     /gene="hemW"
                     /locus_tag="ACHBV5_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFM9966047.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(54889..55278)
                     /locus_tag="ACHBV5_000171"
     CDS             complement(54889..55278)
                     /locus_tag="ACHBV5_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFM9966048.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(55251..55677)
                     /locus_tag="ACHBV5_000172"
                     /pseudo
     CDS             complement(55251..55677)
                     /locus_tag="ACHBV5_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
     gene            complement(55678..56466)
                     /gene="lgt"
                     /locus_tag="ACHBV5_000173"
     CDS             complement(55678..56466)
                     /gene="lgt"
                     /locus_tag="ACHBV5_000173"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFM9966049.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(56459..57394)
                     /gene="hprK"
                     /locus_tag="ACHBV5_000174"
     CDS             complement(56459..57394)
                     /gene="hprK"
                     /locus_tag="ACHBV5_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFM9966050.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(57524..57700)
                     /gene="rpsU"
                     /locus_tag="ACHBV5_000175"
     CDS             complement(57524..57700)
                     /gene="rpsU"
                     /locus_tag="ACHBV5_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFM9966051.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(57840..58547)
                     /locus_tag="ACHBV5_000176"
     CDS             complement(57840..58547)
                     /locus_tag="ACHBV5_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFM9966052.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            58698..59726
                     /gene="queA"
                     /locus_tag="ACHBV5_000177"
     CDS             58698..59726
                     /gene="queA"
                     /locus_tag="ACHBV5_000177"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFM9966053.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKIVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(60387..60776)
                     /locus_tag="ACHBV5_000178"
     CDS             complement(60387..60776)
                     /locus_tag="ACHBV5_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HFM9966054.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(60880..61536)
                     /locus_tag="ACHBV5_000179"
     CDS             complement(60880..61536)
                     /locus_tag="ACHBV5_000179"
                     /inference="COORDINATES: protein motif:HMM:NF019142.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HFM9966055.1"
                     /translation="MFRRNLNTSFAHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVK
                     VATKPKVVTKKISSTRIRFEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTE
                     QVTVDRKEATDTVIKVPAKSKIEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTT
                     ITYNVDGKSGQVTESTLSQKKTLKQELLKKEPSPKFLSKKFQSKQNISMAQLLIKVKK
                     "
     gene            complement(62235..62786)
                     /locus_tag="ACHBV5_000180"
     CDS             complement(62235..62786)
                     /locus_tag="ACHBV5_000180"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9966056.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSTENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(63185..64009)
                     /gene="nadE"
                     /locus_tag="ACHBV5_000181"
     CDS             complement(63185..64009)
                     /gene="nadE"
                     /locus_tag="ACHBV5_000181"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFM9966057.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(64006..65466)
                     /locus_tag="ACHBV5_000182"
     CDS             complement(64006..65466)
                     /locus_tag="ACHBV5_000182"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFM9966058.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIYNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFPEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DENGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(65582..66070)
                     /locus_tag="ACHBV5_000183"
     CDS             complement(65582..66070)
                     /locus_tag="ACHBV5_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HFM9966059.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(66060..66269)
                     /locus_tag="ACHBV5_000184"
     CDS             complement(66060..66269)
                     /locus_tag="ACHBV5_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM9966060.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(66654..67382)
                     /locus_tag="ACHBV5_000185"
     CDS             complement(66654..67382)
                     /locus_tag="ACHBV5_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9966061.1"
                     /translation="MKLNKLNFLKESIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYAWNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(67398..68268)
                     /locus_tag="ACHBV5_000186"
                     /pseudo
     CDS             complement(67398..68268)
                     /locus_tag="ACHBV5_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
BASE COUNT        20579 a        15404 c        12670 g        20012 t
ORIGIN      
        1 ttatctacaa cctcaaagct gtgctttgag caacctacgg ctagcttcct agtttgctct
       61 ttgattttca ttgagtatta cagtgaacaa tttttctagc tattgtaaca aaaaagtcac
      121 tcgaaggcaa cttttttcgt ccataaactt tcaaaagaga atggcttatt cagaactaaa
      181 agccgcagct ttttgcattt ggtaatactt accctttcta tccatgagtt cttgatggtt
      241 accatattca acaatatcac catctactaa gacaagaatt aaatccgcat cctgaatggt
      301 tgacaaacgg tgagcaatga tgaagcttgt gcggcccttc atgagttttg caaaggcatc
      361 ctgtaccagc acttctgtcc gtgtatcaat ggaagaagtt gcctcgtcta agataagaat
      421 ctttggaata accagaaaga ctcgggctat ggtcaagagc tgagcttggc cgacagagag
      481 agattctcca gcattttcca acttggtatc gtatccctgt ggcaactgtt ggatgaaaaa
      541 gtctgcatta gctgctttgg cagcagcaat tacttgctct cgactggctt caggattgcc
      601 aaaggcaata ttatcatgaa tggtcccttg tgtgagccag gtttcttgaa gcaccatacc
      661 aaactgctgt ctcaatgata ctcgtgtata atcataaatg gattgcccat ccagcaagat
      721 atctcccgag ctaatgggat aaaaacgcat aaggagattg ataagagttg attttccagc
      781 acctgtcgga ccaacgatgg ctatcttact accagctgga atatcgatag acaagtcctt
      841 aatcaaaatt ttttcaggat ggtagccaaa agagacatgt ttaaaggaaa tagctccctt
      901 aacttggtca ctggtcaaga cttccttacc tgtttcagcc acttcagggc tatctaagac
      961 tccatagata cgctctacgc aagccagagc actttgcaac tcagctagca ctgaagaaat
     1021 atcattaaag ggcttggtgt attgctgaac atagttcaaa aaagtcacta aacgaccgac
     1081 ggtcaaggtt gaacccatca tgatacgata agctcctact ccagctaaaa gggcataaat
     1141 gagtgcattt acaaagcgag tcgaaggatt gaccgttgaa gaataaaaga tggctgactg
     1201 agaatagcct gagtagttgt catgagcctc acgcaatctt tggataaatt ctgtttgagc
     1261 attgaaggac tggattatag tctgctggct aagcgattct tcaatcaact gagtctgaat
     1321 tcccctcgtc tctgtttgct tctggaagag atgataggat ctcttggcaa taaagcgtga
     1381 aatcaccatg gacagtggcg tcaacagcaa gactaagaga gtcatgagga gatgaatttg
     1441 gagcatggct agaatactaa ccaaaatcat caaaacacca atgaaaaatt ggttaaaaat
     1501 catggtcaag ccagctgcca actgttcgat gtccgtggtt acacgactaa ccatctctcc
     1561 actaccttgc ctatctacaa aagcaatcgg taaacgatgg agcttatgga tgattcgctc
     1621 tcgcaaatct ctagtataag agaagattag acgattatag aggagaggat tggcccattg
     1681 taccagagta tttcctatta ccaccaagag catctggaga aaaatctgcc aaaaaactgg
     1741 tgatgaacca gccactagga cttggtcaat gacctgccca atcagaatag gtaggtaaat
     1801 tgataagcca acttgggcaa tagttcctag aaaggctagg aaaaggagga agggatggtt
     1861 tgctaaatct acggctaaac gtttgagcgt ctggtttaca gtttgtcgtt tcattctagt
     1921 cctcctttcc atgttgggat gcattgattt cacgatagac ttggctggat ttcatcaagt
     1981 catcgtgctt gccaacagct agcaactcac ctttttccaa gaggagaatc tggtccgcca
     2041 tctgtaaagt tgaggttcgt tgagagatca aaattaagct cgtgtttgga aaattttctc
     2101 taatagcttt caagagcttg gactctgtaa tggtatccag tgccgaggtt gcatcatcta
     2161 ggatgataaa cggagcttgg cgcaagactg ctcgggcgat agacaacctt tgtttttgtc
     2221 cacctgagaa atttcgcccc cctgcctcaa ctagggcatc caaaagtcct tccttatcac
     2281 tgacaaaatc cttagcttgc gcaatctcca aggcctgcca gagtttctgg tcagatactt
     2341 cttgattgaa acctagagtc aagttggaac gaatggttcc tttaaagagt tcgacctttt
     2401 gaggtacata ggcaatccaa gaccgccact gctccaaatt aagaggacta cgtccatttt
     2461 gataaaggtc aatgttcccc ttgtctactg gataaagtcc aagtaagagt tgcaccaagc
     2521 ttgatttacc agaaccagtc cccccaatga taccaaggat ttgtccttga gtcatatcaa
     2581 aggaaatgtc tctcagagaa ggctgggccg catcaggata ggtaaaagtc aattcttgga
     2641 cttgtaaaac ccgaccactg gtaacttgct tttgttctaa ttctgaatgg atgttttcgg
     2701 gagattccgc aaagacctcc tcgattctct tggctgagat ataggactgg ttgagggaat
     2761 tgatcagcat ggcaagcttg accaattcca ccaaaatctg taagaggtaa ttgataagag
     2821 caatgagagc accttgactg agcactcctc cttgaattga aatatagcct tgccagataa
     2881 taacgagaag agttccattg acaatcagat aggtcagagg tgttaataaa ctagaccaga
     2941 aacctgtctt ttcttgtaat ctagcataaa cttggttaag ggtttgaaaa atctgtaact
     3001 ctcgtttttc ttgaccaaaa gcacgaataa cccgcatccc ttgcaattgc tggcgcgttt
     3061 cctgaaccag ttggtccgtt ttctttctga gactactgta gagaggattg accaatcgag
     3121 atagccctac aatgacaatg gtcaaaatgg caaccatgac taagaaccag aaagtcaact
     3181 cagctgagat tcgataagcc ataaaaatgg caccaaaaac gataatgggc gctcgcaaaa
     3241 agagacgcag gaattgattg ataccagtct gaatctggta ggtatccgaa gtcaagcgag
     3301 tgaccaaact agaagttgtc agacggtctc tgctgtcctt ggacaaggaa agaatatgac
     3361 gataaagatc gtttgtcaat tccttagcaa agcctactgc tgcctttgct gagtaaaatt
     3421 gagctatcaa ggccactaaa acgccaatta ctgcaaagat aaggagcagg ccaatctgca
     3481 tccagagatg accttgatct ccctgaggta aagattggtc aacaatccca gcaatcacca
     3541 tgggaaccaa gagctcaaaa acagcttcta acagcttgaa caagggggct aaaattgatt
     3601 ccttgatgta gggtttgaag taagataata ggtgtttcat aaatcccttc tattcatatt
     3661 ctagaaatga agaaagtggg aagccccact ctctgtttta tttgtttaag taaggcaata
     3721 gatagccata tcctgctttt tccatctcat ccttggccac aaagcgtaaa gaagcagaat
     3781 tgatacagta acggaggccg cctaactccc gcggtccatc tgtgaaaaca tgacccaagt
     3841 gagcactgcc tgaacgagaa cgaacttcaa ttcgctccat tccatggctc agatccttgt
     3901 aataatgaat caactctttg gaaatcggac ggctaaaact tggccaacca caacctgaag
     3961 caaacttatc cttggcaaaa aagagtggct cacctgtcgt aatatctaca taaatcccct
     4021 cttcaaaggt ttggtcatag gcattggtaa atggagcctc tgtagcagct tcttgtgtga
     4081 cacgataaga ctcttcagat agactggcct tcaacacctc ttgactaggc ttttcatagt
     4141 ttgctgcatc aatcaatggc ttatcagcat cggtcacatc gatatgacag taacctgaag
     4201 gattcttcct gagatagtct tggtggtagt cttcagccag aatgtagtgg cgtaattgct
     4261 ccacttctac tgcaatcttt cgacccagca tgcgttcctg ctcctgtacc actgtgtaga
     4321 tagctggcaa atctgcttca tcctgataat aaatcccagt tcgatattgg cgaccacggt
     4381 cattcccttg ttgattgata gatagaggat cgataactcg gaaataataa agtaaaatct
     4441 ctctgagtga cacttccttc tcatcgtaaa tcacttggac cgtttctgca tggtctgttt
     4501 ccttgatcaa ctggtaattg gtcgtttcga cttgaccatt agcgtagcca acactggttt
     4561 ctagcactcc agaaatgcgt gaaaaatatt cctctaggcc ccaaaaacaa ccacctgcta
     4621 gataaatttc tgccatcttt atttctcctt tatcacgttt ttaactaata ctcttcgaaa
     4681 atctcttcaa accacgtcag cgtcacctta ccgtatatat gttactgact tcgtcagttc
     4741 tatctgcaac ctcaaaacag tgtcttgagc tgacttcttc agttctatcc acaacctcaa
     4801 aacactgttt tgagcagcct gcggctagct tcctagtttg ctctttgatt ttcattgagt
     4861 ataaacttct tttcacaaaa aggatatgaa accctctggt caagagtttc cccatcctat
     4921 cttctattct ttattttgct tctacacgga caccttgggt atcaactctc aagtcatgca
     4981 gttttccttt gaaaggttgc ttttccaatt ctgccttaat tgttggcatc ttgtcatgag
     5041 aagccagaac cataactgtc ggcccagcac cagaaaggta ggttgcatag gccccatttt
     5101 ctttggtcac ttgcttaatc atcgcaaatt ctcttaccaa gtcctgacga tagcgctcat
     5161 ggaagaggtc tccctcgatt gcttgcccag cggtcaccat gtctcctgcc aacaaggcag
     5221 caaccgctac attggcgata gaacttgcag cagcagcttc cttataagac aattttttag
     5281 gcaagacact acggctgtcg cgagtacgta attcatagtt tggaatgtaa gctagaaaat
     5341 cacactctgg aaagtctgct acgatagcag agacttgccc ttcaacagaa cttgcaataa
     5401 cgagattacc ataaatggct ggagccacat tgtcaggatg cccttcaatc ttggtcgcta
     5461 actgcaattt ttcatggtct gataagttga gttgacccag ttggttggct agttcaatcc
     5521 cagcaacgat aaccgagctg gaagaaccca aaccgcgcgc caaagggaca tcactggtca
     5581 ttttcaagcg tcttggttgc aagtctggta caatttgcaa agcgattttg agcaagagat
     5641 tacgctcatc atgtggaatc catttgccaa tctggtgttc aatcagccac tcatctcgtt
     5701 cttcgcagac ctcaatttga agatacttgg ttacagctac accgaccgag tcaaaacctg
     5761 gcccgatatt ggcactggtt gcaggtacaa taatcttcat cttattctcc tagcaccttg
     5821 aaggtattca agaggtcgaa ttctgaaacc ttcttcaatt cagctgagac attttcaagc
     5881 tgggctttat taatcttgtg tgtgatgata acgacacgcg ccttgtcacc ctctttgcca
     5941 tcttgaagga tttgcttaaa ggaaatatct tgagcattga agatttcagc caacttcaag
     6001 acctgacctt ttgagtctgg agccaagatt gagaaatagt agtttgcttt gacatcttca
     6061 ggatttgcca agaccaagtc acggctatat tcgttgaagt ctttgccaat ggtaccatca
     6121 ttcaaacgac gaacgatacg gacaatatca gctacaacac ttgttgcagt tggtttttga
     6181 cccgcacctg gtccgtagta catagactca ccaataccga tagattctac aaagacagcg
     6241 ttcattacgc cattcacact agcaagtggg tgcgctttcg gtaggaaggt tggagtcact
     6301 tctgcagcaa tacctgaaga agtttcctca atagaaccaa ccaatttcac tacgtaacca
     6361 agctcttgag ctacagctac gtcttctggt gtgatattgc ggattccctt gtgggctaca
     6421 tcatcaaagg caatcttcat gccaaaggca aattggctca aaataaccat cttgtaggct
     6481 gcatcaatcc catctacgtc attcgtcgga tcgctttctg caaatcctag acgttgtgct
     6541 tccgcaagag catcatcgta agaccagcct tcttccacca tcttggtcac catgaagttg
     6601 gaagttccgt tgactactcc aagcacgcgc gtaattttat cagaagccaa ggaatttgct
     6661 aaagtacgaa gaattggaat cccaccagca actgctgctt cgtagtaaag tgctaccttg
     6721 ttagcttgag cgatttctag caattctgcg ccatggacag ctaaaaggtc cttgttagca
     6781 gtaacaacgt gttttccagc ttccaaggca cgagtgataa aggttttagc aggctcaata
     6841 cgccccatca attccactac gatagtaata tcctggtctg ataaaatatc atccacattg
     6901 gttacaaagt taaagtcatt ccctgctgca agcaagcgat ttttttcatc ttcatccttg
     6961 accaatacct tagcaacttt gatatctgaa tgtgctgatt gattgatttt tcctccattt
     7021 tcctttagga ggaaaggcac accacttgca acggtaccaa atcctagtaa agcaatttta
     7081 actgtcatct ttatctcctc gaaattttct aatatagcca ttataacaga attttgtgaa
     7141 aattcctatt atagtaaatc actatttcag tataaaaaga aaaaacgaat cagacgattc
     7201 gctcttctta aaatctgaaa atagctttcc agaaaggatt agccgatttt ttgcagattg
     7261 agcactgcat cgtgactcat caagacttga ccatactctt gtaagactga gcgactgata
     7321 tcactatcgt ctgcaaactc gcgcatacgg gccaacagcc aagctggata tgggcttgga
     7381 tgattttcaa tatccactaa aatggtcaaa taatagcgct cgttcatttt gtagagttca
     7441 gaagtttcca tttcaaaagt cactgtcttg gcaaaagcta ccaagtcagc caacttagca
     7501 aaagaaagga tgtagtagat gtaaggttct ttcttactct cagcttcttg ttcagcctgc
     7561 tcttgctctt cttccttggc ttcaacttgc tcaagagatt gaatggcttc gatatcatcc
     7621 ttggttttgt ctgcgatgct tttttccagg gttttgataa attcatctgg agacatttga
     7681 gccaattctt ccatatctgg caaatccgat aagtcttcaa aatctagatt ttggtcaatc
     7741 tttgacttgg tcacaaagac atctacctta tcaggttttg gagtcacacg gaagctcaac
     7801 atgcctgtat ccagaaagct atcaggcatc tctagctcat ccaagatagc ataaaagaac
     7861 tcttctgttt tttcttgagg aacgagaaag tcagcaatct ccattccacg atccatcaaa
     7921 tcctctaaag acatcgtgat ttttaaagtt gtatcactaa tttgtttcat tttcattgct
     7981 agtaacctca tactttcagt tctatctatt atactagatt tttacgattt tatcaaaaga
     8041 aggctcctct atacggatag attttcccta gggtctttct ataggagact ccaagagaaa
     8101 atttctgcag acagatagaa aaagccttca aaatcggctc ttagccgatt ttgaagacct
     8161 tatacatcag aatacttata atttaaaggt tgctacaccg aggatagaac gatttaagtt
     8221 tctgagaatt tgaagacttt gctcaaattt cttataacga gtcactccgt actcttcaac
     8281 aagaaggact gtatctcttt ccaaaagaga tgatacatcc tgcaaatcta caaaatgcat
     8341 tccttttaaa gcttcttgac tctgtttcaa tttatctagg atagctttat ttgagctaac
     8401 gatggtcaat tcctgtccag tatttttgta tgacaaaaca tctgctaggt tagcaattgt
     8461 tgtaatctct gttacaaaat caatttgata ctgagaaaaa tcacctactc tattgattgt
     8521 tggattaaag agataaacta acacatttcc catcacaacc aaaatcacac aaaccactcc
     8581 aataacaact aaacgaagaa tcagattttt cacatttaag ccaagcgctg tttcaccatt
     8641 tgcgttcaat tctttagagt tgatggtttc cagtttttca attttcacat ttgcataagc
     8701 atgtttaaat ttctcaatca acccatcaat ttttttctct aacaagtcat tggcatcttt
     8761 acttgatgtc aaaattttca caccaacccc tgcatcgtca atcatatagt agacggtcaa
     8821 ttttttccac caatagtcat tcgttgaatt tttcaaggtt gtttccgtcg tgtctaattc
     8881 actggcaatt tttttcaact cactgggttc tacatcattg aaaagataag ctccattcaa
     8941 attaccatca atcaatttcc cataaaaatc actataacca ccaatttgat gattcaaaat
     9001 cgttttggcc gaatcttctg gaggagtgat tttatagata agataagttg aataacttgt
     9061 tgtatctttg acagtgtttt tattcctaac tgctttaatt gtaaatggta cagcaatgag
     9121 agcaaataaa gcgatgagag ctaaaatatt tgcttttcgt tttttataaa gatttgcaaa
     9181 caaatcagct actgaataat gttcaaacat gatttttttc tcctttgttt agtagatact
     9241 agttttcctt tgtaagcatt tttgctacaa atataatcac aagaacaatt ccccagaatt
     9301 gcattgtaaa taaattgaag aaactttctg aaaagctgct tcttggcata aagaatagat
     9361 tattcaagat gagtagggat aaagcaaata ggattgtcct tgagcgatag gctacttgca
     9421 gcatggctat aaataatacg ccgagtaaga aactaagcag aaagactcca atcataccat
     9481 agtcggtata caactccatg atataactac ttccgatacc atgccctttc aagtattcct
     9541 tgttcaagac aagataggat agattgtggg cataactatt actatcaata gctagttcca
     9601 cactattggt tgtatgttca aaggcttttc ctccgaaaat ggctcccaaa ctcccccttg
     9661 caaaataatc aagaacagga ccaaaagtaa aattacggaa atctcggtaa gggaggctac
     9721 tgttaaatag aaaacctcga gccagaacac caaaactagt cccttgttta tagataaagt
     9781 caagtaagat atcccagaaa cctgtatgag aaacttggac attatcccgt acataattga
     9841 gtactcccat cgctaacatg agaataggag aacctacaaa aatcgctaac ttttctttaa
     9901 acccaatcca ttttcctttt tcagtttgct cccgcataaa gtaataaaca aaagcaaata
     9961 aaatacttaa aataaaggga tttcgtgtcc caattgccaa atgaatagta ttagctgcaa
    10021 taaaggagac aagcactgct gtggcctgca atttctttgg cttggttgcc agatacatac
    10081 acattgcata gaccgtaaag gtagacaaaa tgtaggtaaa ataaggcagt ttactttcaa
    10141 aatttgcata gtaggcatag taggaagtct gcaaacgata caagagccgt tcaaataacc
    10201 gaatgaaata gaaaggatag gttagaagaa aaactcctag tgatacaaag cgtaaccgct
    10261 tgatataaac ctcttttaga gaatttccta tatttgctac ttttattttc ttcctagcta
    10321 tgaagtaacg agccagaatg cctcctgtgg tcaagcccag aatcgaaacc atgacaacta
    10381 taaaggcaaa acgataggct attggatgat aggtatccaa agcaccatcc ctaaaataat
    10441 caatggtcgg tcttgatacc agaaatacaa aaatggttaa atagaaaata aaatggatta
    10501 agtaatactt gatatcattc caacaagcaa ttaagctact aaccaacaag aacaataaag
    10561 tagaaagtaa gctaacatta ttattattat taaacagata cacaattcca cttactagcg
    10621 tcaaggcata actgactatg gtcaaactaa ataataatcg tttcccatca atcacttggt
    10681 cacccccgtt ctaatgtaat tttttagatt tttcaatatt tttcagtaat aagaatcgat
    10741 ataaggaaat atttatgaat agggccaaag cactaattct tctcccctta cggaaaattg
    10801 gattcctaga aatagcaaag gcatggcctt ttaaaaaacg atgaatctga gaataggctt
    10861 caaactgttt atactgatca tctagcaaca tcttatccag aataaagaag tgggcatagg
    10921 ccaatctgaa aaaagcgacc tctttcaagt caggatagtt tttcacaact tcattataaa
    10981 acttttggta gatatcaata taggctaaat ccttctctgc atagggtttg gtcgtaatac
    11041 tatcccctct atggaaatag taataatagg gtttagtatt aaccacatac ttcttggcca
    11101 acttgattaa atcaaaatgg taataggcat cttcgtaaat caacccctta ggaaaggata
    11161 gggcagttgc aatctgtctc ttgattagct tattgcaaat cgtcccaggt attttttcac
    11221 ctatgaggta ttcctttaga aatgtttgag aatcacagac aaaatagtca tcctgattgg
    11281 ctgactgtgg gctttcatca ttagcataga cattcatgac accacagctt gaaacatccg
    11341 catcttcttg aactaattgc tcatataagc tctgaatcat ttctggatgg atataatcat
    11401 ctgagtcaat aaaaatcaga taatctccgt gagcctgctt catcccatca tttcgtgctt
    11461 gcgacaatcc ttcgttcttt ttatgaagca ctgacaccct gtcatcttgt tcagcgattg
    11521 aatcacacaa gcgaccactt tcatctgttg caccatcatc aacaagaata atttccagat
    11581 tttgataggt ctgcttctga atggaagcta tcgatttttc taggtactgc gccacattat
    11641 agactggcac aatcacacta attaatgcag tttccatgct actcctctaa tagtttttct
    11701 acttgttcga tttgttttgt aattgtaaat tgttgaatga attggctagc ctcatcgaca
    11761 tcaaagtttg aggcagaagt catgtaatta gtaatcgcct gagctgcctc ttgattgctc
    11821 tcaatgattt gtccaaatcg tccttcttgg gataattcct cagcccctcc aacgtccgta
    11881 gagataaaag ggagtcccag actcaaggcc tccacataca ctccaggaaa accttcttgt
    11941 ttagacatag acaagagaac tttcgtctga gatagatact gataaggatt tttttgataa
    12001 ccaaggaaat gtacatagtc ctcaatccca tactctttga ctcgtttttt cagttcctct
    12061 tccatatcac cagccccgat aaaatagaga tgatagtttt ttccctcttg gtgtaataat
    12121 cgtatcactt ccactacacg gtcagaaccc ttattttcct caatccgtcc gatagtacag
    12181 atactttgag gagcaatctc gatatcgatc ttctcttgag atttttctag aatagtctga
    12241 aaatcatatc cattgtagat tgtctgtaat ttagaagcat aatctggata aacttccttg
    12301 atagaattgc tggtcttttt tgaaatccct acaattgtat tcgcagcatc caactggctt
    12361 ctatgtgatt ctcttttaga gctatcctta agaagttctt caatacttcc atgaatccaa
    12421 gatatcttct tgacttctct tcttttagag aacaacagtg gtggattcat aatggtaaaa
    12481 gaaacttcaa catcataatc atcttttaca agcaaacgac gagccagtct tggaaaataa
    12541 attctcattc tccacaaaaa agctcgtaac catctggttt ggcgataatc ttgaagggat
    12601 tttaaaatgc gtacatgctt tggaacagat tcatatccct tgtcaaagtg ctccatttca
    12661 agaatatcaa tatcatactt ttctagatcc agatttgaaa caatggttga tagaatcttc
    12721 tctgcaccac ctccaagaga aaaagaccac ataaaaaata agattttttt cttagccacc
    12781 atattctccc ttgtattctg tataagactt atccatatca gcgatgacag catcatgatg
    12841 cggtacctgc ttgtctgctg gtggaggcgt catataatcc ccaaaagcag ttctgagata
    12901 gacatcatag ccgattggaa taggcatctc tgttccttca aatggcaaga aaagattgtc
    12961 ttcaaaagat gtgattgggt acttgtttct catgtagcca ggacctgagc ataattctgt
    13021 aatgccatca caatcagcca aatcatactt agtcatttct ttctcagctt ttttccagat
    13081 gcgataacgg agagattttg gagtcaaacc cagtaaaatg cgacttcccc atttcatgag
    13141 agcaccatgc ttttctggaa tagtttgcgc acaaaagagt gaataaatca aggcccaacg
    13201 aacctgtttt ttccgctcag ctggatcttt cggataataa tccaaaggca aaacatccaa
    13261 ggccagacca tgtggcaaat ccaaatcctg ctgataaggc ttgatacagg tggtttcctt
    13321 gtcacgaatg gtaataaaaa gattacgatc aacaaaatcc ttgtaactct ttgacaagaa
    13381 ataacgttca tctgcataac gaggccataa ttctgctaat ttctcataat ctttacgagg
    13441 cataaaaaag tctaggtcgt cgtcccaagg aataaatccc ttgtttcgaa gggtaccaat
    13501 agcgcctccg ccacagagat aacagagcaa atcatgttct ttacaaaagg ccacaaaata
    13561 ttcagccatc tccagactac gagcctgaat tgcttttaaa tcagtcatat tgttcattat
    13621 tctttctatc gtatcgtttc attataccac aaacaagggg tgaaaatcta ttgcagactg
    13681 taaaaaatca aagcctgact gctatccaaa tagctatcaa actttgattt ttctgtctta
    13741 tactcttcga aaatctcttc aaaccacgtc agcttcacct tgccgtaggt ataggtaact
    13801 gacttcgtca gtcttatcta caacctcaaa actgtgtttt tagcagcctg cggctagctt
    13861 cctagtttgc actttaattt tcattgagta ttatcttatc tcaagcccat ttgagcgagc
    13921 ttggtttgat atttgttttg atcaaccagc aagcccaagc ctccataaac atcataggca
    13981 tctacccagt cacccagttc tggaatcgtc aatttttcaa taccattttt tgctccatcc
    14041 aaaacagata aaccgtttgt taggaggaaa gtatagggta cgttggttga ggtcatagca
    14101 aaaacctttc caagagcttc agaaccagtg aaaagtttag tgggatcttt aatttgctct
    14161 aaaattgctg ttaaaacttg ttgctgtctt tttgtacggc cgtaatccgc ctcatcatca
    14221 tcacggaaac gagcataatt gagcagggtc gagccattca tctgctgttt tccgacttta
    14281 atggtttggg ttggagactc agtctcggta gcatataaat catctccgac tgtagcttct
    14341 gttaggggac gcccattcaa tgttgaaaat tgagcatcaa tcgtcacccc atcagggaaa
    14401 agcgtgtcaa tcgctgtggc aaaggcctgg aaatcaacca aggcgtagta cttaatgtcc
    14461 aagtcaaaat tatctttcaa gacttggcga accatttctg cccctttttg cccctcttgt
    14521 tctcctaact cgtaggctac gtttaacttg ttatctgtct gttttctacc attaatcact
    14581 tgactataac catctatata gaccaaatta tcacgcatga aactgactag cttcattttc
    14641 ttatctgagc ccccgacatt taataccata atagagtcag ttcgtgtctc aacactgttc
    14701 tggccgattc gaccatcagt acccatgatt aaaatattaa ctccatctct agtgtcctga
    14761 ccattaaata cttctacttg agctgcccgg gcatcagcag ttttctttgc gctagcatct
    14821 tggtaaccac gcaaaaacat gaataccatg gccaaagcca cacagaccaa aagtgaaaaa
    14881 atcaccataa aaattcgttt aagacggagc ttccgtcttt tcttttttgg agggaaagag
    14941 agtgcttgtg atttggattg tgagcgactc cggttcgcat agcttggtaa gtcaacctgc
    15001 tcttctcttt cttgttccaa gctagagcta ctatttcccc tagcaagagt tagcttttct
    15061 tgcaaatagg caaactcatt tttttctctc tcattgagat agtgaatatt ttttagcaaa
    15121 taatcataac gcaactgctc atgatgactt aagggatttt ctttactcat cttctctcct
    15181 ttccatggtc tgatattgga taaataggat aggcacccag aattttatac tggattccaa
    15241 tcgcttctaa ttctttttgg gcaaagtgga ccaagtcctt atcggtataa tccacatcga
    15301 taatgaaaaa gtattcaccc agtgctgtct tgagtggacg actttcaatt tttgtcaagt
    15361 caattcctcg ccaagcaaag gtcgacaggg ctttataaag tgcacctgga aggttgtcag
    15421 gtagggtcaa ggctaaactc attttttcag tttgtgattg caagggaata gttacacctt
    15481 cagctcccaa aacccaaaaa cgtgtgaaat tggcttccat ttcctgaata tcctcggcaa
    15541 tcagttccaa tccatattct tcagcagaac ttctaggtgc aactgctgca aagggctgat
    15601 ctggatgttc ggaaataaaa cgggccgcat aagctgtact agctgttacc tcgatttgag
    15661 cctctggata ttgttcatcg atgaatttct ttccttgagc caaggcctgt ggatgtgaaa
    15721 aaatcttttc aatcttagta tggcctggaa ccaccatcaa ctgctgatga ataggctgaa
    15781 cgatttctgc tactgcttgg atgtgagcct gatgaaaaag atagtccaag gtttcatgaa
    15841 cactaccctc aatagaattt tcaactggca ccacagaata gttcactaat ccttgctcat
    15901 aagccttgat gacatctgta atgttggcaa aagcctgcaa ttcctcatga ggaaaagctg
    15961 tctgcacaac gtggtgtgaa aatgatccct tgggacctag ataagctatt ttcatcttag
    16021 ttcctctata atttcctctg ggcttagctt ggtcacatcc aaaacccgac tagccacttc
    16081 ctcataccaa gcctgtcttt cttgaaaaat agctactagt tcttccttgc tattatttag
    16141 aaaaagcggt cgctgattgt ccttatcagc tgcgatacgt aggtagaggg tttcaaaatc
    16201 tgctttcagg tagatgttat ctgtattagt cttgagtaag tcacgatttc tctgagaaat
    16261 aaccactcct cctccagttg acacgacttg gtctgtttgt agtaaatcag ctaggacttc
    16321 tgattctacc tgacgaaagg ctgcttctcc cttttcagcg aaaaaattcg caatggacat
    16381 acctaggcgc ttctcaatca gagcatccat atcaaggtaa ttagggtcca agcctcttgc
    16441 aatagtcgat tttccagccc ccataaaccc taataacacc ttagccatga atcaagctct
    16501 ccaaatcatc aaagaaacta ggatagctgg tattgatggc ttctgcacgg tcaagctcca
    16561 cctctccatc tgcaaccaag agggctgcga tagctgtcat catgccgata cggtggtcac
    16621 caaacgtatt gactctagca ccgtgaagag ctgatttccc tttgataatc atcccatctg
    16681 ccgtaggagt aatatctgct cccatactat ttaaggcgtc tgccacaacc tgaatacggt
    16741 ctgtttcctt gaccttgagc tcctcagcat ccttgataac tgttacacct tgggcttgag
    16801 tcgcaagcag ggcaataatg ggcaattcat caatcaatcg tggaatcaaa gcgccaccaa
    16861 tctctgttcc tttcaagtca gaagactcaa caatcaaggt agcagattta gcgactggat
    16921 cgatttcagt tatttccaat tttccaccca tggcacgaat gacatcaata ataccggtgc
    16981 gagtttcgtt gatccccaca ttctgcagca ctaaacgaga atttgggaca atcaaacctg
    17041 cgactaacca aaaggatgca ctggaaatat ctcctggtac gaccaccttt tgtccagtca
    17101 gtttttgagg tccttgaact gtgattttct tgccatccac acttaaatgg ccaccaaatt
    17161 gttgcaacat atcttcagta tgattacggg tgcactcttt ttcgataata actgactccc
    17221 ccttagcttg taaggctgca aacatcaagg ctgacttgac ttgggcagag gcaattggca
    17281 actcataatg aataggtctt aggtttttcg tcccttttaa gcgaagggga ggcaagtctc
    17341 gttcagtttg ccctgagatg ctgacgccca tttttttcag tggaagggtc acacggtcca
    17401 taggacgttt ggaaagacta tcatctccaa acatctctac ttcgaaatct gcaccagcaa
    17461 ggacacctga aatcaggcga atcgaggtgc cagaatttcc catattaagg gcattttgcg
    17521 gcgcttttaa gccagccatg cctacacctt gaatggtaat aaccccatct ttatcctcaa
    17581 tttcaacacc aaggtcacga aaaacctgca tggtcgaaag aacgtcttca cctcgcagaa
    17641 tatcataaac cttggtctca ccctcagcca aacttccaaa gataatggaa cggtggctga
    17701 tagacttgtc acctgggacg cggatactac catgtaaatg gcgaatattt gtttttagtt
    17761 tcatactgga cctcatactt gcaatacttt tacctatttt atcataaaaa gccagaaatt
    17821 ccttaaaaat tcctgacttt aggatagttc ttttcttatt tcagcaattc tgaaactggt
    17881 tcgaaaacaa ttttttcaat gtcagaaagg taaatggcca attgttgttg cttggtaaag
    17941 aattctgaca agaggctatt tccttgaatc tgtttaccaa agccttccat cttagcttgg
    18001 aaggacgcat ctggcatttg acctgtctgt gctagttttt gaatttcctc ttgaaaggca
    18061 agatattctg taaagatttt gcttgcctca gcatctgctg caatcgcatc tttagctgct
    18121 ttaacagcct tgtattctgg taatccgcgt agaccgcgac tgagttcgtt tgcactatcg
    18181 taaatatttg acatgttctt ctccttattt aatgacgact gtatagtcgg tattttttgt
    18241 tatgagatgc tcggctcttt ccaagtcttg agcattttta aatgaaattt gtaggattcc
    18301 gtgaatatcc tcacgatttt cctcgttgat gtggatgtta accaaggaag tcccacgtag
    18361 cagttccaaa atccgcagga tgacatcttc ttcatcagga acgtcaacat agaggtcgta
    18421 agagctatcc acaccaccac gcttatggat ttccatggtc tggcgttgtt cacgcgcttg
    18481 gttaaaaaag ttccaaattt gctcttcatc tcccttacta atggcctgac caatcgattc
    18541 caaacgttcc ttgaaatcct caattctatc cagaatggtc tcgctattgg acaagagaat
    18601 ggaggtccac attcctggct cgctttccgc aattcgggtc atatctcgaa aaccacctgc
    18661 cgcaaagcgc cttgccatct catgctcttg agcatagacc gcagtctgct ccatgagact
    18721 agaagccaaa atatgaggaa aatggctaat ctgagaagtg acacgatcat gctccttggc
    18781 atcaatctcg ataaaacgag catgaagacc tgaaagcaga tccttcattt ccttaagcgt
    18841 gtcctgactt gtcaggcttg aaggtgtaaa gatataatag gcattttcaa aaagattgac
    18901 atctgccgaa gcagcccctg tcttgtgact accagccatg ggatgggccc cgacaaagcg
    18961 aacagacttg ccagccaaat actgctccgc cgcatccaca atggttgact tggtcgaacc
    19021 agcatctgaa ataataacgc cttctcgcaa atccaaattg gccaactcct taatgaaagc
    19081 aatagtttgt ttgattggca agctgaggat aatgacatct gccaaaggag caaaactagc
    19141 aaaatcatcc gttgcacggt caatcatgcc ttctttcaag gcgatatctc tcgaagcttg
    19201 actacgatta taacctaaaa tttcataatc tggatgatcg cgtttgatac caagtgccat
    19261 agaggctcca atcaacccaa gacctgcgat atagattgtt tttgccatag gaactcctta
    19321 atagttcttt gtatagtctc ggtgtttggc taccgcttct tttagttcct caagattatc
    19381 tgatgagaat ttttcgagga tctcttgcgc cagaaccgtt gctacaactg cttccatgac
    19441 cattcctgca gctggaagag cagtcggatc acttctctcc acggttgcct tgtaaggttc
    19501 gtgggtttcg atatccacac tcataagagg tttataaaga gtaggaatgg gtttcatgac
    19561 cccacgaaca acgatgggtt gcccattagt cataccacct tcaaaaccac ctagattatt
    19621 ggtacggcga gtataaccgt cttctttaga ccagagaatt tcatccataa cttggctgcc
    19681 tttacgataa ccagcctcaa agccaagacc aaattccacc cctttaaagg cattgataga
    19741 gacaacagct tgagccaatc ttgcatccaa ttttctatcc cattggacat aggaaccaag
    19801 accaactgga actcctccga cgactgtctc cacaacccca ccgatggtat caccatcacg
    19861 tttgatttgg tcaatatagt ccttgatttc ctgttctcgt tcttggttga caatagaaac
    19921 ttcagactgg gcagctcttt gcttaatttc agcgactgtc agattttcag gaacatctat
    19981 ttccttacca ccaaagacca cgacatggtt ggcaatctcc atatccagct cagccaagag
    20041 gcgtttggct actgcaccaa ctgccacccg catggtggtt tcacgagctg atgaacgctc
    20101 caaagaattt cgcaaatcat caaaacggta cttaatcccc ccaaccaaat cggcatgacc
    20161 tgggcgagga tgagtaattt tccgcttgct tttaaggcgg tcttcaatgt cctccgcaga
    20221 catgatgtcc agccatttct ggtggtcctt attgatgaca tccatagtaa taggcgcccc
    20281 tgtcgtcttc ccgtggcgaa cacccgaagt aaagacaacc tggtcactct caatcttcat
    20341 acgaccacca cgaccgtagc caccctgacg gcgtctaaga tcctcattga tatcctcagc
    20401 tgtcaatgga agtccagctg gaattccctc aataatagct gttagacggg ggccgtgtga
    20461 ttctcctgca gttaaatatc tcatacactc tccttatttt accaagtagt ctttcatctc
    20521 ttccagagaa actgggtgaa tggtcgctga accaagctct ggcaccaaga ccaatttcaa
    20581 ggtgttacca cgcgctttct tgtcatgagt aagagcctga taaagcttgt caactttcca
    20641 attttcatag tcaacaggca agccgaattt ctgacacatc tctgtgatag attgggtaat
    20701 gccagctggc atgaggcctt tttcctcagc aaccttggaa atctgtacca ttcccatggc
    20761 aacagcctct ccatgcatga ccttgccata accggcagtc gcttcgatgg catggccaat
    20821 agtgtggcca aaattgaggt aaagacgaat accattgtcc aactcatctt caaccaccat
    20881 cttgcgcttc acctgacaag aatgttcaat caaggtctct gcatgttcca aaatactctc
    20941 aacagaacca ttcagtcccg tcaagagagc ccacagttct ggatcctcaa tcaagccata
    21001 cttgataact tcacccatcc cttcaatcaa ctctcttttt ccgagggttt caagaacaag
    21061 tggatcaatc agaaccccat ctggttgggc aaaggtcccc accatatttt tagcaaatgg
    21121 tgtgttaacg cctgtctttc caccgataga agaatcaacc tgagctgtca aactagtcgg
    21181 aatctgaaca aagtgaatac cccgcatata ggtagaggct acaaatccag ccaggtcccc
    21241 aacaacgcca ccaccaagag caacgattcc atcgctacga gtcagacctt gcttgactag
    21301 aaattcatag actttctgaa cagtagttaa attctttctt tcttcacctt ctaagaaatc
    21361 aaaaacagct acctgaaaac cagcatcttc taggctgagc ttgaccttct ctgcatagag
    21421 agaggctaca tggttatctg tcacaatgac taccttttgc ggttgccaga gttctcgcaa
    21481 ccactgacca gcctgggcca tacaaccttt ttcaatctga atatcataag gatgatgagg
    21541 aatatcgatt ctgattttca taggagagtc tccctttctt tattggtatt tttctgttaa
    21601 agactgccaa atctcttctg tcggcatttc cttgcctgtc cacagttgaa aagcttctgc
    21661 agcttgatag agcaacattc ccagaccatt gactgctgga ttgccctgac ttctagccca
    21721 tttcaaaaac ggtgtttcaa agggttggta tatgatatct gcaactaaga gagtttctgg
    21781 taagactatg ttttcaggaa caggagagga ttggccatcc atgcccacac tggtggcatt
    21841 aactagcaaa tccgactcgg caatccttgc ttgcagttca gaaacatatt ctaaagcaca
    21901 caaatccact ttaaaacctg tctgctcctg taacttgtct aggtaaggtc ttgttttttc
    21961 catagaaacg gaacgaacaa agaccgaaat ctgactgacg ccatccaaaa tagcctgtgc
    22021 caagattgat ttagccgcac cacctgcacc cagcagggtc atctttttac ctgaaattgt
    22081 aaaagaaggc aagcacttaa aaaatccctt gccatctgta ttatatccaa ttaaattgcc
    22141 attctcattg acaaccgtat taaccgcacc aatcaagtgc gcttcatcgc tcagcttatc
    22201 caaataagga atcacctgct ccttataggg catggacaga ttgatgccaa acatctggta
    22261 gcgacgaata ttggccactg tttctgccaa gtcactcgct tcaatctccc aagccacata
    22321 agcaccgttg gtagctgtcg cctcaaaggc tctattgtgg atgaagggag aaatagaatg
    22381 cttaatagga ttggcaacaa ctgcagctaa acgtgtatag ccatcaagct tcatccaaaa
    22441 tctccctgat ttttttcatg ctagctagag aaatctgccc aggggcacta acctcatcca
    22501 gactggcaaa agaccaactc gaaccagtca catccgcagt gatacgagag accttgccca
    22561 ccttacccat agaaatggtc acatattcct gttcaggatt gagggtttta aagcctcgtg
    22621 tatagttcat caagtctaag acatcctgct ccgtgtgagc catcaccgca accttaacaa
    22681 gttttggatt taggatcgtc aactctgaca agattttcat catgttctca ggtgtttctt
    22741 ggaaattatg gtaactcaaa acaagatttg ggaagtccag catttcctca aaaacatcct
    22801 tgtagctata gtactcaaaa tcaatatagt ctggttgata gagttgcgca acttccttga
    22861 ttagatggat atactcttct ggagaaaggt cgatttctcc accttcggag cgagttcgta
    22921 gcgtgaaaac caactcacgg cctgcgaatt tttcaaaaat ggctggagct acctgcaaaa
    22981 tcgcttcttt aggcagatag tcggcacgcc attcaatgat gtcggcatcc aggtacctcg
    23041 tggcatccag agcctgagcc tcctctaaac ttcttggcat tactgaaacg attaatttca
    23101 tttactaacc ttcatactaa tcaccttgag gtaattacta ctttcatctt ttttattata
    23161 ggcaaaatct gctggaagac catatttgtt taaaatctgg taacttcttc ctgcaaaacc
    23221 tttatcaatt tgttctgtaa atttctgacg ggaaacattg gcagcattgg tactggcaat
    23281 gataatccct cccggattta aaatctcaag actctgggaa atcaacttgt gataatcctt
    23341 ggccacagag aaagtttgtt ttttattccg agcaaagcta ggcggatcta ggacaatcac
    23401 atcgtaggtc aagtctttgc gtttggcata tttgaaatac tcaaagacat ccatgactat
    23461 aaaacgatgc tcgtctgtgc tgagcccatt tgcctgaaaa tgcgcttgag acaattctcg
    23521 tgaacgtttg gctagatcaa cagaagttgt ctggctagct cctcccatgg ccgcagctac
    23581 tgaaaaagcc gctgtgtagg aaaacatatt gagcaaggat ttacccatag ccaagccgtc
    23641 aactaaacta ccgcgaacct catgctggtc taggaaaatt cctgtcatca agccatcatt
    23701 cataaagact tgatacagga caccattttc taaaacagtg aaaaagtcag gtgcttcttg
    23761 accataaaca tgggcagatt catagtccaa acccttaaag cggattttct cataagctcc
    23821 taaaacctca gggaaaacct gtctaaaggc ttctgatata gtctgacgaa tctgataaac
    23881 ataagagtta taccaagaaa agacggcgta gtcgccataa aggtccactg tcagaccccc
    23941 aaagccatct ccctcttgat taaagagacg aaaggcagtt gtcaaatcat cttgatagta
    24001 ggcgtttctc ttttctttgg cttttctaaa caacgtttca aagaaagctt gattgaaggc
    24061 caccttgtct ttgctgataa accagcccaa gcccttgttt tgctgagaaa ggtaggcagt
    24121 cccaagaaag tttccttcct gaccctgcac ctctacttcc tgatccttaa gattgacatt
    24181 ctcaagatca ctggcttcta gtaaaactag ccccttagca agcttctttt caaccctttt
    24241 gctgactctt attctattca taactaccat tatatcaaac ttttagacaa ttctcaaaaa
    24301 agaaactacc cttgcttttt tactcttctt ttaaaaaatg gtatactaga cttcctgcaa
    24361 aactaggaag taaatgtgta agaatcacag taaaaaatgc tcttccgtct tggaggagca
    24421 tttcttttta tcaacgaaaa tcaaatagca aactatgaaa ctagcctcag gttaaccgtg
    24481 agattatagg tagagaggtt gtatcagcaa tatgtgtctg tcaaatttag tgacaaaggt
    24541 agtagaagaa agatgaagaa ataaatcagc ttcagtagat atctggaaaa tttgatttta
    24601 tagaaaagcc ttttgttaca aactcaatat actatcaata aataatatta tagaagcaac
    24661 aataattaaa atttcaccta tttgcatcat tctatttcga actctaaata tatgttctat
    24721 caaaaatact tggatcacac acattatagg aattaacgtt tttgaaattg aaaaatatcc
    24781 caataaataa actataaaca acaataatag aactatatta tatttcttat tcaaaacatt
    24841 cctccctata tttttgatta ccaatcttaa tcatttacaa ctacattcta acaaactata
    24901 aaagcgtttg tcgaattgaa tttatcaagc aagcaaccaa ccagctcatc ttttttctat
    24961 ttctgccaat atgcgtgaca ggtaataatg atagccaaaa atagcaagag caagcaagac
    25021 gataagagct cctactccca agttgatggc aaggataggg gagagagact gaaccaagaa
    25081 tatgctccca attacaaggg ccatcaggat tgcactataa ataaacaata aaactatggc
    25141 gactatgcca tttgaacgat tcaccaggtc cgtaatgcta ctccaattgg ttgacagatt
    25201 tttaacgtcc ttaaagtaat ggtggcaaga aaggatgaca ctggcaagga tccatgccac
    25261 aataaggtaa atcatcgaaa tgatgggcaa gcctagatat agagaaagac caagcaaagt
    25321 cagaactggt aaaaaggact ggacagcata tataatccaa aatttcactt tcacataacg
    25381 agcaaagtca aagggtaaac tcttaagaaa atcaacattt tccctctcca aggacaaggc
    25441 aattgaatgc aggctggtga tattgttatt gacaactgct ataaacactc ctacaaaaaa
    25501 caagggtaac cagtatggag gatgaatgtc tggaactatc tgagaatctc ggattttgga
    25561 aatcagaccg atcatcatga gataaggaaa gaaagcactt gtaaaaagca ctgtaaccac
    25621 gccagtaccc tgtcccaaga gggtgaggtg gtagcgtaaa accatgcgga aaaatccctt
    25681 tttagtggtt gaaattctct ccttgctgcg acgttctttt ttgaccttct cctcactatt
    25741 aagcaggatc acgtcataaa aacgaggaag gaccttcttt ttggtcagat aaagcaggaa
    25801 gagagttagt cctatccaag cgagcagacc caatatggct tctgtcgaaa aaggatccac
    25861 tgctattttg taaaagatat gaagaggata aaggagaaat ggaatgtctc taactttgtc
    25921 aacaatactt ccaaaagtcg actgaagaaa gaagataaat attaaaggta tgagaactcc
    25981 tatcccaatc atcacattcg aaaaaataga ctgatacttt ctgaagaccc tagtttgagc
    26041 caagaaatgc actgccacta ccatcactag agccacagag acaaataata aggtcaagga
    26101 cagtagcatc aaaggcaaac ccagccatag agaaggagct agcctaatgt agaggaccag
    26161 aaaataagct aggattggta caattccagt tagagctggc aaaaggacag acagtccttt
    26221 agcaattata atctctgatt ctttaaaggc atagggccta tacgatatca aatccttact
    26281 ctcataaaag acattgtaaa aggccgttaa agaagttgaa aaggcaatca ctagtaaaat
    26341 agcaatcatc aagctaaaat aaataggtat ttcctcaaaa ggaaaatgaa tggctatatt
    26401 actaaaacag atgatcatca agagactgga aaaaatgtaa gaacttaaga ctctagcgga
    26461 aacatttact tttttcccag gattcttagc ctgcttcttt cgtagattag ccagattagc
    26521 ttcttgagat gaataaagga tattgatatc aactaatttt ttaatgacct tgagacgcat
    26581 ccgcaacctc ctcttttcta ccagcaagac taaggtagat actttccaaa gactggtctg
    26641 ggtaatcttt tctcaagtcc tctacactac cacaataaat caaatgcccc tttttcaaaa
    26701 tggcaatccg atcacagact tgctctgcca cctctaggac atgagttgaa aacaagactg
    26761 tcttcccttt ttgtgcatgt tccttcatca tctgtttcaa atcaaaggca gcctggggat
    26821 ccaaaccagt caagggttca tccaagaccc aaatatcggg atcagacaag agtgctccga
    26881 tgacaaagac tttctgacgc attccgtgag aaagagtttc aataacctga tagcgatttt
    26941 cagcaaaatc aaaaacgttc aatagcctag ctagactagc ctccaagtca gatctactca
    27001 gatcatagga tgaggcgatc aattcccaaa attcattggc cgttaagcgt aaaaataagt
    27061 caggcgagtc tgctacgtag ccaatctttc gtttaatagc caagcgattt tccgataact
    27121 cctgaccgtc taccaaaata cgaccactgc tgggtgaaat gatactgact agggatttta
    27181 tagtggtcga ttttccagcc ccattatgac caatcaagcc cataatctct ccattttcaa
    27241 tctgcaaatt gagattactc aaggcctttt tatcaccata caacttacta acattttgaa
    27301 attcaatcat gggacaactc ctatctttat ctgtattata tatcgctata ctagcacttt
    27361 gatacaaaaa aatcaatact ttattttaag tagttaaaat agtttccttc tatcttacgc
    27421 aaacgtttgc gctaatagat actttatgat agaataaaga acaagattga caagtaagag
    27481 gaaacattat gcaaaatcaa acactcatgc aatactttga atggtatctg ccccacgacg
    27541 gtcaacactg gacgcgtctg gctgaaaatg ctccacacct agctcatctg gggatcagtc
    27601 acgtctggat gccaccagcc ttcaaggcaa ccaacgaaaa agatgtcggc tatggggtct
    27661 atgacttatt tgacttagga gagttcaacc aaaaagggac tgtccgcacc aagtatggtt
    27721 tcaaagaaga ctatcttcaa gccattcaag cccttaaagc gcagggaatt caacctatgg
    27781 ccgatgtggt tctcaaccac aaggctgctg ctgatcacag ggaagccttt caagttattg
    27841 aagtggatcc tgtagaccgt acagttgaac ttggagaacc cttcaccatc aatggctgga
    27901 ctagttttac cttcgatggt cgccaagata cctacaatga cttccactgg cactggtacc
    27961 acttcacagg tacagactat gatgccaaac gccgtaagtc tgggatttat ctgatccaag
    28021 gggacaacaa gggctgggct aacgaggaat tggtcgataa cgaaaacgga aactacgact
    28081 acctcatgta tgccgaccta gactttaaac atcctgaagt catccaaaac atctatgact
    28141 gggctgattg gttcatggaa acgactggtg tagctggttt ccgtttggat gccgttaagc
    28201 atattgactc tttctttatg cgcaacttca tccgcgatat gaaggaaaaa tacggtgacg
    28261 atttctatgt ttttggtgaa ttttggaacc cagacaagga agccaatctg gactatctcg
    28321 aaaaaacgga agaacacttt gaccttgtcg atgttcgtct ccatcagaat ctctttgaag
    28381 ccagtcaagc tggcgcaaac tatgaccttc gtggcatttt cacagatagc ctggttgaac
    28441 tcaagcctga caaggctgtg acttttgtcg acaaccacga tacccaacga ggacaagccc
    28501 ttgagtctac cgttgaagaa tggttcaagc cagcagccta tgccctcatt ttgttacgcc
    28561 aagacggcct tccatgtgtc ttttacggag actactatgg gatttcaggc cagtatgctc
    28621 aagaagattt caaagaaatc cttgaccgcc tcctagccat ccgaaaagat ttggcctatg
    28681 gagaacaaaa tgactacttt gaccatgcta actgtatcgg ttgggtacgt tcaggtgctg
    28741 aaaatcaatc cccaatcgca gtccttatct caaatgacca agaaaacagc aagtcaatgt
    28801 ttgtcggtca agaatggact aatcaaacct ttgtagattt acttggtaac caccaaggtc
    28861 aagttacaat tgatgaggaa ggttatggac aattccctgt ctcagctaga tccgtaagtg
    28921 tctgggcagt caataccatc taatagctca taataaccaa gctaggtcca agcggatttg
    28981 gcttttttgt attcacaaaa agacctaccc aaatggatag atctttactt gattacaatt
    29041 tacctgctac tgcatccaac aattcttgga tcttaggttg gttgcttcct cctgccatgg
    29101 ccatgtctgg tttaccacca ccacgtccat cgatgattgg tgctaattct ttgacaaggt
    29161 ttcctgcatg aaggtctttt gtcttgcttg ctacaaggac attgactttg tcaccgatag
    29221 cggcaactag gacaagaaga tcagagtagt ctttttgttt ccagttatct gcaaaggtac
    29281 gaagggcacc tgcatcggat acagacactt gactagcaat gtaacgatga ccgttgactt
    29341 ccttaacatc tttgaagata tcgcctgcgg ctgcagctgc ggctttttct ttcaactcag
    29401 cattttcttt ttgaagttga cgaagttgtt cttgaagtcc ttctaccttg tgaggtactt
    29461 ccttgacttg aggtgctttc aaggttgctg cgacagcttt aagagcatcc tcttgttcac
    29521 gataggcttc aaaggcttcc ttaccagtca ctgccaagat acggcgagtt cctgaaccga
    29581 ttccttcttc tttgacaatt ttgaagagac caatctcaga agtgttgcca acatgagtac
    29641 caccacaaag ttcaatagag tagtcaccga tagtcacgac acgaacttcc ttgccgtatt
    29701 tctcaccaaa gagggccata gctcccattt ctttagcagt gtcaatatcc gtttcaactg
    29761 tcttcacttc aagtgcttcc caaattttct cgttaacttg ctgttcaatc gcacgaagtt
    29821 cctcagcagt tactgcttgg aagtgggtaa agtcaaagcg aaggaattca acttcgttaa
    29881 gagatcctgc ctgtgttgcg tggtttccaa ggatattgtg aagggcagcg tgaagcaaat
    29941 gagtcgcagt gtggtttttc atgacacggt gacggcgatt gctatcaatt gccaaggtat
    30001 attcttggtt caaggcaagc ggtgcaagga cttcaactgt atgaagggct tgaccatttg
    30061 gggctttctg aacattggtc acagtagcca caatcttacc tgactcatcc aagatttgtc
    30121 cgtagtcagc tacctgtcca cccatttcag cataaaatga cgtttccgca aagataagag
    30181 aggcagttcc ttctgaaaca gctcctactt ctgcattgtc agcaacgata gctaccaatt
    30241 tagaagacaa ttggctagta ttgtagttga agacactttc tacagtgatg ttttgaagag
    30301 tttcattttg catacccatt gagccaccct tgacagctga cgcacgcgcg cgttcttgct
    30361 gttctttcat ggctgcttca aaaccttcac ggtctacagt cataccagct tcttcagcga
    30421 tttcttcagt caattcaact gggaacccat aagtatcata gagtttaaag acatcttgac
    30481 cagcaatgac agattgacct ttttctttca agtctgccac aatgccttgg gcaaagtgtt
    30541 gacctgagtg aagggtacgg gcaaatgatt cttcttcgct cttaacgatt ttctcaataa
    30601 agtcacgttt ctcaagcact tctgggtagt agctttccat gatttttcca acagttggaa
    30661 ccaatttgta aaggaaaggc tcgttgatac ccaatttttg accatgcata gaagcacgac
    30721 ggagaagacg acgaagaaca taaccacgac cttcatttcc tggaagggca ccatcaccga
    30781 tagcaaatga aagagaacga atgtggtctg cgataacctt gaagctcatg ttgtcgccat
    30841 cttggtcata aaccttacca gacaatttct cgacttcacg gataatcggc atgaagaggt
    30901 ccgtttcaaa gttggtctta gccccttgga taacggccac caaacgctcc aaaccagcgc
    30961 ccgtatcaat gttcttatgt ggcaattcct tgtattcgct acgaggaaca gcagggtctg
    31021 cgttaaattg tgacaaaacg atgttccaga tttcaatata acggtcgttt tcaatatctt
    31081 ctgcaagcag gcgaagaccg atattttctg ggtcaaaggc ttccccacgg tcaaagaaga
    31141 tttctgtatc tggtccagaa ggtcccgcac cgatttccca gaagttgtcc tcaattggaa
    31201 tcaagtgact tggatccact cccacttcaa tccagcggtt gtaagaatct ttatcgtctg
    31261 gatagtaggt catgtaaagt ttttcagcag ggaaatcaaa ccattcaggg cttgtcaaaa
    31321 gctcataagc ccaagtgata gcttcgtcac ggaagtaatc cccgatagag aagttcccca
    31381 gcatttcaaa catggtatgg tgacgcgcag tcttccctac gttttcgatg tcgttggtac
    31441 ggatagcctt ttgggcattg gtaatacgtg gattttcagg gataatggtc ccgtcaaagt
    31501 atttcttaag ggttgctacc ccagagttga tccacaaaag agttgggtca tttacaggaa
    31561 ccaaacttac tgatggttct actgagtgac ctttggtcgc ccagaaatca agccacattt
    31621 ggcgtacttg tgcactagat agttgtttca tattgtctcc ttattcactt gtttaatgtg
    31681 attggctttc cagcatttcc acatagtcaa tcgcgacaca gagggaaatg actaggtctg
    31741 cataagcgtc ttcaagaacc gttacggtat aggtagaggt cagatggaag agttccttct
    31801 taatttccgc aatcaactga tcgcgatcat ccagcaattt gaaattcaaa tcccagatat
    31861 tgccctcgat acgaagacct agattatcaa actcatactt atctcgccag aaggtcaact
    31921 tcttacgaat gacaaaactc gagccatccc gaagctgaat ctcaaaacga ggaagcaagg
    31981 tcaagatttc tttactgatc tgactgactt gttcaccagc cgcatcatag atggtaaaag
    32041 ttttgggaat cttaaaaaat gatccctcca cctgataggc aatttctccc ctgtcatcct
    32101 tgatagcgaa gcgttcgcct ccaagacgaa acttttgttt gacaagaaat gttttcatca
    32161 acacctccaa aaatcaaaag acaagctcat atcacgaagg gcgaaaaacc gcggtaccac
    32221 cttcattcaa tgaacttgtc attctcttgt tcttatgcaa ttgtatgatt gagtagcatg
    32281 acttcctagc ttagatggct cgcagcaccg ccatttctct ggactaagac aagtgaaaat
    32341 caattctcaa ctttcttatt ataacgtttt tttaagcttg cgtcaactgg aaatgatctc
    32401 cgttgaatta gaccaattcc ctacatctct gattactttt tcaggatata ttttttctta
    32461 ctgccatttt tctttttatc ccaaattttc atattactaa acacagctac tagaatattt
    32521 ccaaatataa aggtgcctat cacccaatat atggactcag ttgttaggta ttgtcgatcc
    32581 aagccatcat ttaaatggaa tagtatagca gtttggttaa caatcataaa ggttggccag
    32641 aaactttttt tgaaaaaagt agacattttc attatttgtt gccgctttct gtaaggttaa
    32701 tactcaataa aaatcaaaaa gcaaactagg aagctagcct caagctgtac ttgagtacgg
    32761 caaggcaacg ctgacatggt ttgaagagta taggcttagt atactactag gcaagcaaat
    32821 aagcaaataa gcaaataagc aaataaacaa ctagaataga aaaagatagg gctctaaaaa
    32881 ctgacttcta ttccttaaaa acgaaccagc ttgactgatt cgtcttctta cgtttatctc
    32941 ctacttccga tacattttaa actgtaggaa gaggtcgcta tatttccctg tccatttatg
    33001 gtcaaatttc tcataaactt ctaggtgttt catggtttca acatcgggat agaaggcctt
    33061 atcttccttt gtttcctctg ggagcaattc cttcgctggt aggtttggtg ttgaatagcc
    33121 gacatactcc gcattttgga gagcattttc aggtttcaac ataaagttga taaaggcata
    33181 ggctgagttt tggtttttaa ctgttttggg aatgaccata ttgtcaaacc aaagattgct
    33241 ggcctctgtc ggtaccacat aacgtagatt ttcatttttt tctaacattt ggctggcttc
    33301 accagagaag gtcacgccga ttgcaacatt attctgaatc atatagccct tcatctcgtc
    33361 cgcaacgata gccttgatat ttggagtcag tttgtagagc ttatccactg tctcttccaa
    33421 ctgctgcaga tccttggagt tgaggctgta gccgagggaa ttgagtccta gtcccagcac
    33481 ctcacgcgcc ccatcaaaga gcatgataga attcttatac tccggcttcc aaaggtcatc
    33541 ccaatgctca ggcgcttcat ctaccatggt ttcgttgtag acaattccta aggttcccca
    33601 gaagtaaggg atggagaatt tattacctgg gtcaaaggac tggttgagaa actctgatcc
    33661 gatattttcg attccttcaa tttttgaata atcaagcgga accaagaggt cttcgtcctt
    33721 catcttgtta atcatgtatt cacttggaat ggcaatatcg taggtcgttc caccctgctt
    33781 tatcttagtg tacatggctt cgttggagtc aaaagtctcg tactgaactt gaattcctgt
    33841 ttcttctgta aactgagtca agagttcagg atcgatatag tctccccagt tatagataac
    33901 caatttttga ctatctcgac tattgatttt actatctaaa tgagtcgcaa ttccccacaa
    33961 gacaaggata atcgctgcaa ttcctgctaa aaatgaatag atttttttca tgcttgctcc
    34021 tccttctcac gagagataaa gtaataacct acaactagga taatactaaa gagaaagact
    34081 agagcagaca gggcattgat ttctaaggaa atccccttgc gagcacgaga gtaaatctcg
    34141 actgataggg ttgaaaagcc atttcctgtt acaaagaagg tcacggcaaa gtcatctaac
    34201 gaataggtga aggccatgaa ataaccagta atgatagacg gagtcaggta aggaagcatg
    34261 atttccttga acatctgaaa ttgactagct cccaagtcat aggccgcatg aatcatgtcg
    34321 ccattcattt ccttgagtcg aggcaagacc atcaagacca cgataggaat ggagaaggcc
    34381 acgtgactag atagaacggt caaaaagcca agtgaaaact tgagttgggt aaagagaatc
    34441 aagaagctag caccaatcat aacgtcaggc gcaaccatga ggatattatt gagtgataga
    34501 aaggcttctt ggtatttctt acgagactgg tagatgtaaa tggcaccaaa agtcccgata
    34561 atggtcgcta tcaaggctga taggaaggcc aagaaaaatg tctgagccaa aatcagcatg
    34621 agtctcccat ctccaaacat ggtttcaaag tgagtccagc taaaacctgt aaagctattc
    34681 atatcatcac cagcattaaa ggcatagcca atcaagtaaa agataggcag gtagaggacc
    34741 agaaagacca gtcccagata aaggttggca aattttttca tcgttctctc ctttccttag
    34801 tcacccacat ggtgatgaac atggtcagga tgagaatcac accgatggtt gaacccatac
    34861 catagttgtc attggttaga aaattctgct caatagccgt ccccaaggtg ataacgcggt
    34921 tcccaccaat caaacgggtc agcatgaaga gactcaaact tgggataaag accgactgaa
    34981 ccccacttcg cacaccgttc atagatagag ggaagatgac atgacggaag gtctcccact
    35041 tagttgcacc aaggtcataa ctagcattga tgagattatt atccatatcg tctaagacat
    35101 tgaaaatcgg caaaatcata aaggggagct cgatgtagct tgcgacaaag ataaaggaaa
    35161 aatcggtaaa aagcaactgt tgtgaaccaa ttccgataaa ttccaagaat tggttaatag
    35221 agccattttg accaaaaatc ccgataaaag cataggcttt aaggagcaaa ttgatccagg
    35281 taggaaggat aatcagcatg agccagagtt gacggtgctt gagacgggtc aaaaagaggg
    35341 ctgttggata gctgataagc aaggtcacaa aggtcacaat ccctgcataa agcactgagt
    35401 tgaaactcat tttgaggtag gtcaagtttt gtgacgcaaa gtaagattta taattttcta
    35461 aactaaactg gccttcaatg ttgaaaaagg attgtccgaa aatcaagacc aagggtgcca
    35521 atacaaagag ggcaatccaa agcatgtagg gcactacaaa gagtttagag cttgttttct
    35581 tcatctcttt cctcctcgat cgcattgatc agacctgctt cttgctcttc gatttccacg
    35641 tattcttcga tacgagcatc gaactcttct tcggtttcat tgagacgcat gatgtggatg
    35701 tcttctgatt caaagtccag accgatttcc tcacccacga tggccttacg ggttgagtgg
    35761 atcatccatt catttccaag ttcgtcatag gcgataattt cataatgaac tccacggaag
    35821 agctgggtgt cgaccttaac ttggagtttg ccttcttcag gaagggtaat gcgcaagtcc
    35881 tctggacgaa taacgacctc aacaggttca tttggcttca tcccaccatc aaccgcttca
    35941 aagcgtttgc cgttaaattc gaccaagtag tcctcaatca tggtacctgg caagatgttt
    36001 gactccccga taaaggtggc aacaaagtgg ttgattggct catcgtagat gtccacaggg
    36061 gttccagact ggacaatctc gccatcattc ataacgaaaa tccagtcact catggcaaga
    36121 gcttcttcct gatcgtgagt gacaaagaca aaggtaatgc ccaatcgttg ttgtaattca
    36181 cgcaattcgt actgcatgtc tgttctcaat ttcaagtcca gcgctgataa aggctcgtcc
    36241 aacaagacca cacggggttg gttgatgata gcacgggcga tggccacacg ctgacgttgt
    36301 cctccagaaa gtttgcggat ggaacgtttt tcataacctt ccaactgaac catcttgaga
    36361 acttccgcta cgcgttgctc gatttctttc ttgtcaatct tgcgcaagcg aagtggaaag
    36421 gcaacatttt caaacacatt catatgtggg aacaaggcat aggattggaa gacagtatgt
    36481 acgtcgcgct tgttggttgg aatatcattg atacgaacac cgtctagcat gatatctcct
    36541 gtcgtcgcat ccagtaaacc tgcaataatg tttaggatag ttgatttccc cgaaccagat
    36601 gcacctagaa gggtgtagaa tttcccttct tccaactcaa agttgatgtc tttgagaacc
    36661 ttggtgttgc tgtcttcaaa aactttagag acgtttttga attcgataat tggttttttc
    36721 aattggcata aattccttct ttttcataga ttaaccgatc ggggctctgt caggtcccca
    36781 ctacctcttg cagggagtaa aaccacctgc atacatcttc gctaccgata ggctttcacc
    36841 cccctttcca tgacatagca gcagcttttc aaatacagct tcctacttgc tttcacccaa
    36901 gatccggact tctctttcaa gcgtaatacc tgagtgttcc ttgacttttt cgataaccga
    36961 ttggatcaag tcctcgtagt ctttggccgt tccatctgcg acattgatca taaatcctgc
    37021 atgcttttct gacacttcta cgccaccgat acgatagcct ttcaagccag cttctgaaat
    37081 taactgacct gcaaaatgcc cgactggacg cttaaagacc gagccacaag atgggtattc
    37141 caaaggttgc ttgagttcac gtaggtgcgt caagcggtcc atttcctgct tgataacctg
    37201 atgggttcct ggggctaggg caaatttaac tgacaagaca actgcaccag actcctgaat
    37261 agctgaatgg cggtaaccaa aagccaagtc tttagcagac agggtttcga tttctccatc
    37321 cttggtcaag accttacaag actgcaatat gtgagcaatc tcgccaccat aggcacccgc
    37381 attcataaag acagcaccgc caacgcttcc tggaatacca caagcaaact caaagccagt
    37441 caaactatga cggagggcaa tgcgagttgt ttcaatcaag ttagccccag cttctgcttc
    37501 aatggtatag ccatcaacag aaacgttatt gagcttgtca cacaagatga caaatccacg
    37561 aatcccacca tcacgaacga tgatattgct tgcattgcca agaaccatcc aagggatatt
    37621 ttcttggttg gcaaatttca caaggcgagc caactcaaaa cgatttcgtg gaaagaccaa
    37681 ataatcagcc tctccaccta cttttgtata actatagcta tgcaagggtt cctgaaaacg
    37741 gatatcaatt ccttctaaga tttcaagcat tttttctctt acagacatgt cactcttcct
    37801 tttacaaaat tcattccatt ataccatttt tagagacatt tgacgaccat aaaaatacct
    37861 tgtttggatt ttgcataaga aaaagaggtt cccctctttt tatgattttt tacaaaagat
    37921 ttccttggtt ccataggcga ccagaacgag ctccagtgct agaatcactt caaccaagac
    37981 tggatttgtc aaccagccta cttggaaaag agatggtgcc agatcaaaga aggcatgcaa
    38041 gccataggct gttaggagat aaatccattt cttctggcga acagcttgat aaacccaaac
    38101 tgtcaaaagt aattggaaac caagcgccaa gattcgctca aaaccaagca aataaatctg
    38161 ccagaccgaa agtgactgaa tggtttttaa catattttca gacagtaatt gcataacctg
    38221 tggattctga gtttgaactg ccgaaagaac aatgtaaaga ttgagtaaac tagtaaggcc
    38281 tagaaaaatc aactccaagc caccatgccc caatccatag gccaaggcgt ctgccttttc
    38341 caaacttctc tttttctcca accatttgaa gaaaacaaga cgagccgttt cctcaaaaaa
    38401 tgctaccatg gctaggccat agataatata gataagcgga tgaacttaca agagggcaat
    38461 actaccgtct ttttgaggat gcaaaatcaa gatatgcacc agtttttcca aaatctgcga
    38521 agagacaaag aaagcgactg cacccaagtc caagacagct agattaatct ggtatttctt
    38581 tttggcaaac caaatgcttc ctatcagaaa agctagcaac agcaacatgg taataatgat
    38641 atgaatggtc attttcttct cctattctgc cttttcaata tcttttttca tctcgtcaac
    38701 attgaactta gcaaacaagt attgacggtc ttggactggg aaacgttggt ccaactggtc
    38761 aactgctccc acctcgataa tgccttcctt gatgacaaaa tccatgacat gtccaccgaa
    38821 ggtcaaatca tctgatatga agtgcagatg gtagcctgcc acactgaccc catggaaaat
    38881 ctcaggcgtc cagaaaccaa caatagtccc cgcaacattg tcacgactat attccggttg
    38941 atgggttgcg acatcagcaa acttggtatc gggtgttgac ttaggaatca tacgcacatg
    39001 catatgtgaa aattcccccc gaatcttgat agagcggaaa agattttccc catcataata
    39061 agactcaatt cgttctttca attccttgtc tgtcatctca aagcgctggc ggaaaatgac
    39121 ctctgcctga tgcggtacca ctgcagcgta aggaataagg gcatctggtg acacttccac
    39181 aatttctggc tggtctcctg accctttggc ctgataagcc ttgccatcca agacaatcaa
    39241 ttccccatca atggaatcca aggttcccaa accaaggtca ccatgttcta gcaattctcc
    39301 tactgtcata gtaccaccat aaaggccagc catcaaggct ccaagagtat tgtattgaaa
    39361 taatttcact ggttcctgca cgttcttatc cattcacttt cttgtctgtt attctataaa
    39421 tcttactcct aagtatacca catttgcccc tagatgtgaa cgagagaaac gctctagaca
    39481 ttgccaagaa ggaaaaacag ggtacaatgt aacaaaatca agggaggtct ggaatgaaga
    39541 aacaaagcaa gtacaaagag gtcgtttcct atctgaaaaa tggtatcgag tctggacgat
    39601 ttccgacggg tagcctgaga ttttgacaga aacaaaactt gcactagcac aacaacccct
    39661 aaggaacaca cttccctagg ggtcgctttt tatttaacta aatcattatt tattttttgt
    39721 tcctagtaaa cataaatatt gtattaataa ttgcaaaaat aaatgcaaac aaaaggattt
    39781 tccaaaggat aaatttttgt aacactaaat atgcatatac aaatccaatc aaaaagctaa
    39841 taatcccatc ttttattaaa aagtttttat cacgcattat tccagaccac actgaactgc
    39901 ccaaatagcc aactgaccag caatgatata aatatttgtt ttaagtccat tagctttaac
    39961 aaatcttagt accactttag ctaattctga ccaagccttt ttctgcgcat acttaacaat
    40021 tagcgaaaca ttgatcatag caaaaaattc atctcgtatt tttcctgcta tacatcctcc
    40081 catctcatcc caagggactc tgtcataggg attattaata ttagtttcta attcattttc
    40141 cgcaagagca atatcttttt gagaaaagtt tttataaaca tattcagtaa aatttttttc
    40201 attaactcca tttctaaaca tttgttcaag aacattggct acatcatcga tttgtttttg
    40261 ttcttgggta ctaatttcag aaacttccgt agtagttaca tcatcagcaa atactctaac
    40321 agaagctata gaaggagaca taatagaaaa tagtgataat acaacaagag ctgaagttac
    40381 aattttttta aatttcataa aaaacactcc tttcaagtca caaatatata ttactgataa
    40441 aataacttga ttttctgatt taaaactcct ttctaacaag ttattcgtat gcttttattt
    40501 tttagttcta ttataccaca acaagaaaac gatttcaagc attttcctaa aaatatgtac
    40561 aagtaatatg tacaagtaat aaggggaaat tagcataaaa actttttaaa acaaatcaac
    40621 cccagataaa aatacacatg ttgttttaaa gacaaaaaag ggtacgaaaa actgtcacat
    40681 ctgcatttga ttgctctttg atttcaaaaa agtattaaaa atgggagtat accacatttg
    40741 cccctagatg tgaacgagag aaacgctcta gacattgcca agaaggaaaa aaaagggtac
    40801 aatgtaacaa aatcaaggga ggtctggaat gaagaaacaa agcaagtaca aagaggtcgt
    40861 ttcctatctg aaaaatggta tcgagtctgg acgatttccg acgggtagtc gcctgccttc
    40921 tatccgtcaa ctgagccttg actttcactg cagcaaggac accattcaac gagccctgct
    40981 ggaattacgg cacgaacaat atctctatgc caagcctcag agtggctact atgtattaga
    41041 acaagggcaa catcaagacc tagaaatcga ggttaccgac gaacatgcca gtgcctatga
    41101 cgatttccga ctctgtgtca atgaaacctt gattggccga gaaaactacc tcttcaacta
    41161 ctatgacaat caagaaggat tagaagacct aagacagtcc attcacaaac tcctctttga
    41221 gcaagctctc tactgcaagg ctaaccaact agtactgact tctggaaccc aacaagcctt
    41281 gtttatcctc tctcaaatat cctttcctag acaagccaag gaaatcttgg tggaacagcc
    41341 aacctaccat cggatgaatc gcctcttgat tgcacagggg ctggactatc aaacgattga
    41401 acgaggcatt gatgggattg acttggagga gctggaaggc cacttcaaaa caggaaaaat
    41461 taaatttttc tacaccattc ctagatttca ctatcctctg ggacattcct attctgagca
    41521 ggacaaacga tctattctta acttagctgc caagtatgat gtctatatcg tagaggacga
    41581 ttatctgggt gatttggact ccaagaaggg ccaaaccttc cactatcttg atacagagga
    41641 gcgtgtcatt tatatcaagt ccttctcgac cagccttttt cctgcccttc gtattacagc
    41701 actcattctt ccaaatgcta tcaaagaagc atttgtggcc tacaaaaata tcctagacta
    41761 cgacagcaac ctcattatgc aaaaggccct gtcactctat attgacagtc aattgtttga
    41821 aaaaaatcgt ttggctcgct tgaccaatca tgaatcttac caaaaacaaa tcgaggaaag
    41881 gataactaaa acaccttgtc cccttcctca ttatccccta cacgatggtt tattgctaga
    41941 cctgagacag tatcctaaaa tcgccagtct caaacacagt caactgggct tggacttctt
    42001 tgaagaggcc tatttaagca cctgtcctta tcaatttgcc aaggtgtccc tagacaatct
    42061 ggaaaatgtt ttaaactatt taaaagcaga attggaatga catccaactc tgctttttct
    42121 tattcttcaa cttcagttaa acttgctgct ttttcaagat agctttggta agttccttca
    42181 tccttaagtt tttggatgac cttgtctacc acttctttca aatcatcact attttttcta
    42241 agagcaacgg cattggcgtc gccgtccttc atcttcaagc tgacagttgc gacagctaag
    42301 ccagcgtttt tagcagcata actaagtgca acaggctcat ccatatgaac agcatctact
    42361 tttccagcct gcaattcatt gactgcttca cccatattag ttagggaagt taattgagct
    42421 tttggcaatt gttccttgac cattgattct ggaacagtcc ctttttgggc tgcaatatta
    42481 gcactttcta ggctagttaa atccttgtat ttttccacat cagccttacg aaccaagaaa
    42541 ctaatcttgt tttcatagta tgggattgaa aaatcaaaga cttcttttct ctcgtcagta
    42601 gcactaattc ctgcaactgc taggtcagcc ttaccagttt gaagactggt caaaacatta
    42661 tcaaaactca tgcttgagat ttccaactta accccaagtt catcagcgat agcctgagcc
    42721 atgtcgatgt ctgcaccgac tacctggttc tttccatcaa ccaatgattg aaattcaaag
    42781 ggtgcatagt caggactggt tgccacaact aatttcccct tttgcttaat ggcctcaaca
    42841 gctgactgag aaccattaga acctgactgg caagctacta agaagaaact tgcaagaaaa
    42901 ttacataaaa caaatatcca tttttttgat ttcataaata aacaacctct ctgttaattt
    42961 tgtataatta taacgatatc caagttactt gtcaagtgtt ttttaaattt ttatctcaaa
    43021 aatatttttt cgttcaaaaa aaggagccat cagttgattt caagctcctt tttatacaga
    43081 attaaactat tttatagttc gacaatctta cctgtttcaa agtagacaac ccattcacag
    43141 atatttttag catagtcacc gatacgctcc aagtaggaaa taacttggaa ataatcacga
    43201 cccgtaacaa tggcttctgg atttttctta atctcttcag tcgcaaggtc acggatagtt
    43261 tcaaaatagt ggttaatttg ctcatccatg gaggccaccc ggtatgcgtc gtcaacagaa
    43321 ccattaagat aaagatcaag tgctgcttca acaacgcttt taacttcacg tcccattttt
    43381 ttaatttctt cctctacagc tggaatgcgc tcttccccct tcatacggat ggttgcctga
    43441 gcaatggcta cagcgtgatc ccccatacgc tccacatctg atacagcctt aaggacagtc
    43501 aagactgtac gcaaatcttg agagactggt tgttggagtg cgatcatttc aaatgatttc
    43561 ttttccagtt tcacttcgta ttcatttact tctgcatcat cttcgatgac ctcttttgcc
    43621 aggtcacggt catgcgtgac aaaagcacgt accgtacgat tgatttgtga gagcacttct
    43681 tgtcccatag cgtagaactg gttatgtaat ttctctaaat cttcttcaaa ttgagatcgt
    43741 aacatctttc atctccttat ccaaattttc ctgtaatata gtcttccgtt tccttgtgtt
    43801 ggggattaag gaacatctgc ttggtatcat taaattcaat caaatctcca tctaggaaaa
    43861 atcctgtctt atcagagata cgtgaagctt gctgcatgga acgggttacc agaagcatgg
    43921 tgtacttgtc ttttagacca tacaaggttt cctcaatttt accagctgaa atcggatcca
    43981 aagccgaagt tggctcatcc aagaggatga ttttaggact agttgccaag acacgggcca
    44041 cgcagacacg ctgctgttga ccacctgaca atccaatagc tgaatcatat agacgatcct
    44101 tgacctcatc ccagatagag gcaccttgca aggctttttc tacggcttca tccagaacct
    44161 gcttatcctt aattccattg atacgaagcc cgtagacaac attctcatag atagtcatag
    44221 ggaaaggatt aggttgttgg aaaaccattc cgatttcctt acgtaattca accgtatctg
    44281 tacgcggact gtagatgttg tgaccattgt acaccacgga tccagttgtg gtcacctctg
    44341 gattgagatc tcccatgcgg ttgagagact tgaggagggt tgacttccct gatccagatg
    44401 gaccaatcaa ggctgtaatt tccttaggtt ggaaagatag ggaaacacta ttcaaagcct
    44461 tctttttatt ataataaacg gacaggtctg atacctgtaa aatcgcatct gtcatacggt
    44521 ttcctttcta accaaagtga ccagatacat agtcattggt ggactgtagc ttggcatttt
    44581 ggaaaatagt tgcagtcttg tcatactcaa tcaaatcacc caagtaaaag aagcctgtat
    44641 agtcacttgc acgagcagcc tgctgcatat tatgcgttac aatgatgatg gtaaagtttt
    44701 tcttgagctc aaacatggtc tcttctagtt gcatggtcgc aatcggatcc aaggctgagg
    44761 ctggctcatc cattaagagg atatctggct taacagagat ggcacgagcg atacagagac
    44821 gttgttgctg accacctgat aaggtcaagg ctgacttgtg gagatcgtct ttaacctgat
    44881 cccaaagggc agcctgacga agggaggttt ctacgatttc atctaggact tgcttatcct
    44941 taactccagc acgttcatgc gcaaaggtaa tattacggta aattgactta gcaaatggat
    45001 tggggcgttg aaaaaccatt ccaatgtgtt tacgcatttc ataaacgttg atttctggac
    45061 ggttgacatc aattccacga tagagaatct gcccagttac tttagcaata tcaatggtat
    45121 cattcatgcg attgagactg cgtaagtagg tagatttccc cgatcccgac ggaccaatca
    45181 aagctgtaat tttatttctt tcaaattgca tatcaatccc cttaatggat tcatttttac
    45241 catagtaaac atggacatcc ttagtagaaa gggctacttt ttcttcagga aaggtaagga
    45301 tatgcttctc atcccagtta tatgttgaca tggcttctcc tttaggcagc ggttaatttc
    45361 ttgtgtagat agcttccgaa cttacgagct ccaaagttaa aaatcaggat aaagatcagg
    45421 agcacagcgg cagaacctgc tgatacaatg gttccatctg gaatagtgcc ttcactattg
    45481 actttccaga tatggacagc caaggtttct gcttgacgga agatagagat ggggctagtc
    45541 acactgagga tattccagtt agaccagtca agagctggcg ccgattgccc tgctgtatag
    45601 atcagagctg cagcttcgcc aaagatacga ccagatgcca aaacgacacc cgttacaata
    45661 cctggaagcg cttctggaat aacaacatga accactgtct cccagcgaga aatcccaaga
    45721 gccagaccag cctcacgttg ggtatggtga acgtgtttca aactatcctc tacattacgc
    45781 gtcatctgag gcaagttaaa gactgtcaag gccaaggcac ctgaaatgat tgaaaatcca
    45841 tactcaaact ggactacaaa gatcaagtaa ccaaagagac ccaccaccac tgatggtaaa
    45901 gaggacaaga tttcaataca agtccgcaca aagttggtaa caggaccttt tttagcatat
    45961 tcagccaagt aaatcccagc tcccatagaa agaggtacag aaataatcaa ggtaatgacc
    46021 aataggaaaa aggaattgta aagctgaatg ccaatcccac cacctgcttg aaaagcagaa
    46081 gaccttccag tcaagaaaga ccaagagata tggggcaagc cccgaaccaa gatatagaga
    46141 atcaaggaag ccaagattgt cacaatgatg ctagcaatcg tatagaggac agctgttgca
    46201 agtttatcta atttcttagc gcgcataatt tttctttcct ctttctttcg taatcaattt
    46261 aatcacactg ttaaaaacta aactcatcaa gagcagtacc aaggccagtg accagagaac
    46321 attattattt acagttccca tgacagtgtt cccaattccc atagttaata tagaagttaa
    46381 agttgcagct ggtgtggtca aggaagttgg gataacagct gagtttccga caaccatctg
    46441 gatagctaga gcctcaccaa aggcacgcgc catcccaaag accactgcag tgaaaatacc
    46501 agaacgggcc gccttcaaga tcacacgcca gatagtctgc cagcgagtgg ctcccatagc
    46561 gaaactggct tcacgataat aacgaggaac cgcacgcaag ctatccgttg tcataaaggt
    46621 tacggtcggc aaaatcatga caaagaggac ggaaatccct gacaaaatcc caaaaccagt
    46681 cccaccaaag acactgcgaa caaagggaac gacgacttgc aagccaataa atccgtacac
    46741 tactgaagga atcccaacca ggagttcaat agctggttgc aaaatcttcg ccccttttgg
    46801 tgatacttcg gtcataaaaa ctgctgcacc aatagcaaag ggtgttgcga taagggctga
    46861 gagaatggta acgataaagg aacccaaaat cataggaagg gcaccaaatt ctttactaga
    46921 aggattccaa gttcctccca aaagaaagtc aaagatattc acaccattga caaagaaggt
    46981 cgacaagcct ttttgcgcta cgaaaaccaa aatcatggcc acaaggatga ctatcaaaga
    47041 aagacaggca aaggtcaaac cttttcctaa tttctccaga cgagaattct ttgatggaag
    47101 caacattttc ttagctaatt cttcttgatt cattattgtc tcccttccaa cactgtcaca
    47161 gttccggcag catctttttc aaccttcatt tccttaatcg gaatatactt caatcctttg
    47221 acaatccctt cttgggtctc atccgagaga acaaaattga gaaattctgc agccaactca
    47281 ttgggctgcc ccaatgtata catatgctca taagaccaca agggccaatt attgctactt
    47341 atattttctg gacttaagtc atagccattc aacttcatgc ttttgaccga atcatctata
    47401 taggtaagag ataaataaga gatagctcct ggactttttg atacgattga ttttaccgct
    47461 ccatttgaat cctgctcctg actttgcatg gcagactgac cttccataat gacagtatca
    47521 aaggtagcac gagagccaga gccggctgcc cgattgataa cagagatggg taagtcctta
    47581 ccaccaacct ctttccaatt ggttacctca cctatgaaga tttgacgaag ttgctctgtc
    47641 gttaggttat caacatcaac ctccttattg acaatcagag ccaagccagc taccgcgacc
    47701 ttgtggtcaa caagagcaga agcatcaatt ccgtcttttt cctcagcaaa tacatctgag
    47761 tttcctatat caactgcccc agactgaacc tgggacaagc ctgtaccaga acctccccct
    47821 tggacattga ccgtttttcc aacatggatc gtgccaaatt catctgccgc tacttcaacc
    47881 aagggttgca aggcagttga gccaacagcc gttatggatt ctccacgatc aatccagcta
    47941 gcacagccta ctaaacaagc cgtcagccaa aaagcgataa gagacagagc aagctttttt
    48001 ctttttttca ctgtttttct cctcgaaaat aattatgaat actgtgaatt ttttaagtag
    48061 ttctttatga gttgacgcat gaattcttac caaatttctg cgcaattgat tatttatata
    48121 atataggcta tattactctt tcctaacctc cttttttcat atgtggataa aatctcttgt
    48181 ctatcccttc ccccattgtc acccattata gtcatttcgt gtctcttttt ccccttttta
    48241 atgcaaggga aattactctt cttagatgat aatccaaaag ctagaaaggt atctcaaacc
    48301 tctctactct cccagactag tttacaacta aaaggaaaag attctatttt atgagaaatc
    48361 tagtttacaa gcggtaagaa cgctaataac taaacttctt gtactctttg aaaatctctt
    48421 caaagcagtg ttttgagcta tctatggcta gcttcctagt ttgctctttg attttcatcg
    48481 agtagtaaaa ctacatgtga tggcaatcaa gatatcaaga atcatcctac taaaaaaatc
    48541 catactttca ctataacata gaataagata tttgactagc attttcattt gaatctgagg
    48601 ccttttggaa aataattttt caaaacattt ccagtaacct ttgcaaagcc caagccattg
    48661 cctttaacca aaacttggta ccaaccattt ggcagacttt ctgccagctg aacggtttct
    48721 ccagccgcat acttgacaaa cgcttcttgg ccaatttcaa ccgactgttc gacctgactc
    48781 ggtttcaagg ctaaaccaag agcgaaactg ggctcaaagc gtttcttctt aaaagtaccc
    48841 agatgcagtc cattgcgagc aatcttgagc ttccctaaat ctggcaaaag ttctggcaag
    48901 agataaagct ggtctccaaa aatctgcaag atacccggta gattgacctt caaatggttt
    48961 tgggcaaatt cctgccacaa ggcaacttgt tcacggctga ggttactctt acttgcctta
    49021 aatttaggag ctggattgtt acccttaaac tgtagatggg caacaaactg accctctccc
    49081 ttaaactgat gagggtacat ccgagccgtt tctggcaggt caataccagc taccattcca
    49141 ttgatatgct ctactggcaa caagtcaaaa tcatactctt ccagcaacca attgacaatc
    49201 tcttcgtttt cctcgggtgc ccaggtacag gtcgaataaa ccagacgacc accttcagct
    49261 aacatggtca ctgcatcctc cagaatttct ctttgcaagc tagcacattg actcggataa
    49321 tctaagctcc aatagtccat agcatcaggt tgcttacgaa acattccttc accagagcaa
    49381 ggggcatcaa gaacgattaa gtcaaaatag cctttaaaga ccttgaccaa gcggtcggca
    49441 gattcattgg tcaccacgac atttgtcgct ccaaaacgct ccatgttttc aaccaaaatc
    49501 ttagcccgtt tgcttgaaat ttcattggaa acaagtagcc cctcccctgc tagataggct
    49561 gccagttgag ttgatttgcc ccccggtgca gcagccaagt ccaagacctt cataccagga
    49621 ctgggttggg ctacttgagc caccatttga gcagcaggtt cttgcgaata aactaaacct
    49681 gtagcatgct caggcgattt ccctgaaacc ttcccatagt ggccccaagg ggtttgagta
    49741 atggcatcag aaaaggaaag ttgctcttct tttaagggat tgacccgaaa ggccgaaacc
    49801 gcttcctcct caaaagaggc aagaaaatct cttgcctcat ctcctagtat ttctttatat
    49861 ttttcaacaa atccttctgg aaatttcatt taagttcttt tcctttcgta aatataggac
    49921 tgaatttcct cctgcatctc aagaggcacc atcatgaccg gctgtctggt ttgaaaatca
    49981 ggagcttcac caaaaagggt cacaacccga tagcccagac tttcccctaa aatactagct
    50041 gcggcataat cccatggttg cagataggtg agataggtca acaaatgccc tgacaaaatc
    50101 ttggcaaaac taatggccgc acttccatag acacgaacac caagaaccgc tcggctcaaa
    50161 tcagccagcc cccattcatt ggtttccagc ataccactat tccctgcaat gagaaaatct
    50221 ccaagtggtt tagttttaaa aggagctagg ggcctatcat ttagacaaac tggaaattcc
    50281 ccaccaccgt ggtaacaatc ccctttgacc acatcataaa tcagaccaaa ctgtccctga
    50341 ccattttcaa aataagccat cataacagca aaatcttcct gctgggctac aaaattattg
    50401 gtaccatcaa tgggatcaat gacccaaacc ttgccctctt gaaccgaggc tcgcagacaa
    50461 ccttcttcag cacaaatctt atcctcagga taacgggaca aaatctcacc aaccaagagt
    50521 tcctgaactt ctttgtccag tctggtcacc aaatctgttg gagaggactt ggtttcaaca
    50581 cgcaagtctt cctgcatatg gtcaagaatg tactggcctg ctttcttaac aagctcttta
    50641 gcaaattcaa atttactttc caagagaaat ctttccttcc cctttttctt tggcagcctg
    50701 aactgctcgg taaagtgaat agccactaac cgtttcaaat tctcgtccca aacgtttctc
    50761 ttcgctcttg cttggcacga ccgctttgaa tcccttatag gagtccagta actttttagc
    50821 ctctactttg ccttcatagg cagcttcaac atcattaaaa aaagaaagca ctgaagcaag
    50881 ttcttcagtg ctccacgaca aatctagtgg gtaactatac tgtttgttca ttaactaata
    50941 ccagctctca ttcttgcttc ttttagttct tgcttacgat aactacgagg gagaaaagca
    51001 cgaatctcat cttcattaaa accgatttgc atacgcttgg catcaataat aattggacga
    51061 cgcaaaagac taggatactg ctcaatcaaa tgaagcaatt ccgataccga aatactctct
    51121 acatcaatat tcaatttttg aaaaattttt gaacgagttg aaatgatgtc atcagtacca
    51181 ttttcggtca aggaaaggat gtgttgcaat tcttttcttg ttaaaggact ggtcataata
    51241 ttgtgttcca caaagggaac cttatgtttt tctaaccagg ccttagcctt acgacatgat
    51301 gtacagctcg gtgatagaaa tagtgtaatc atgcttttct cttcttatct atactttgct
    51361 acttctatta tacaaaaaaa taaagcgctt gactagggat ttttagaaaa aaagcctatt
    51421 ttttcaagaa aaataggctt tttgcgaacg attgacacaa ttggatttgg ttaattcact
    51481 cttaacgatg gttttaaacg atatatattt ttatatatgt aaattaaaaa catctttcct
    51541 ttcacttcct acgacttttc agatacagat agccaaagaa gttttcatag agggcaaaaa
    51601 agaggaggaa ggcatgaaga aagaaggtct ctggcaaaat cataataaca ggatccttgg
    51661 ctggatcaaa aagccaggta tcatctccca caaagagaat ttgatggaaa agagtaaaga
    51721 attggtcaaa accaatcaaa actcccccaa gtccaatcat cacaggtaag actactagag
    51781 ccaggagact ttttcgataa agagacaaaa agtccttttt cacaatccta ttgacaaaga
    51841 catagaaact tggcagtgtc actagagcta ctagctgaac caaatgaaag agattcttga
    51901 ccactgcgaa atggtgcaga ccagctgctg acgaacgaaa atcaggcatc tgtaagacct
    51961 gactaaaagg attggtcaga taattcatca agatatgaaa attgtattga atggtttctg
    52021 gttttagata gactcgattc gttaagttta gccactgaat ctccatagga tagaaaatcc
    52081 aagccagata aatggtcaga aggattgaga gggagaggag aaagagcata gagccccaaa
    52141 aggtcaattt agttttcatc aaaatcccac tccgcaaggc tagaaaccac atgtgtcggt
    52201 gcgattggca ggccagctac ttcttctgcc ttagtaaaac ctgtcgtcac caagagcgtt
    52261 ggaatgccat tgtcaatccc agcccggata tcagtcaaat aattgtcccc aaccatgatt
    52321 aactcttcac gttccaaacc taagtgctca accgccttgt ccataatgat ggcatttggt
    52381 tttccgatat aaaccggctt cactcgtgtc gctacttcaa gcagcgtaat cagtgagcca
    52441 gcacctggca aaagaccacg ttccgtcggg atgttgaggt caggattggt tccgataaaa
    52501 tgggcaccct tttgaatagc aagagttgct gtggcaaatt tttcatagtc gacttgccaa
    52561 tccagaccaa ctaccacgta ggcagggttt tccttgtctt ccacataacc agccgccttg
    52621 atggcttcct tgagtcctgc ttctccgacg acatagacag tcttttcaag ccccaaatca
    52681 ttcatatagt cgatggttgc caaagtcgct gtgtagacag tcgatagagg cgtatcgata
    52741 ttaaaattct gagccaacat ctccttaaca ctctctggag tgcgggttgt attgttggtt
    52801 acaaagagat agggaatgtc ccgcttttgc aattcatgaa caaaagtctc tccagcaggg
    52861 attcggtctt tccccttata aatggttccg tctaaatcaa ttaaatagcc tttatatttc
    52921 atctatttct ccctaaacct tttttatttc ttgccaagta atgattgctt gggcattgat
    52981 aaccccatca cttgtaattt catgcttgct ttccagtcca gtccgttcaa cagccgatgt
    53041 aatcacccca cctggtcgaa cttccttgac atacttgagg ttgattttct tgggaatata
    53101 gtgggtcaaa aaatccgctc ccatgacctc aaaaatccag tccaagtatt tactgttatt
    53161 gacatgacca ttcatatcca agtcgtaaaa acgaacatgg taatccttgc tgatcggctc
    53221 ttccaaggat tcatacttcg gtccacggat aagtttttta tcaaaatcag actggtaagg
    53281 agccacaatc tcaggttcaa cagcatggac ttttcgactg tcgcggtcca tgagaacaaa
    53341 ggtcgccatc atatggatga gctcctgccc cgcttcatta taaatagtaa agcgacggta
    53401 gcaaaaaagt cgattgtagc tcaaggcttc cgtttcgatg gtaatttctt ccgcaaaacg
    53461 aggcaaacga accacctcaa tatcatattc tgcgataatc cagaccagat tatagtcttc
    53521 caaaatggcc ttatcactaa ctcccagttc aatcgattgc atccctgaaa cttgcagtga
    53581 cagcaaaatc acatctggaa gtttgatatg accgttcata tcagccatat caaaaggaat
    53641 tttcattttc atttgataag ttaagcacat gatcctactc caaaataaat cgttctgcta
    53701 cagtatctcc caaaaagaga cctctctttg tcatgcgaac gtggtcaccc tcaatctgca
    53761 tgaggccttg ttgaaccaaa tctctgacaa tttctccata aagtccagca aaagactgtc
    53821 caaatttttc ctcaaatcgc gccatggaaa ccccggattt cttgcggagt cccaagaaca
    53881 tttcttcttc catttgctcc ttttgactca ggtgatcttc tgtaatacaa gcattgcctt
    53941 cctcaaccgc actgagataa tgacgaatgg gaccatgatt tttatagcgt actccattga
    54001 cataaccaga tgcccctgca ccaataccat agtattcagc attgtcccag tacatgagat
    54061 tgtgacgact ttcaaagccg ggtttggaga aattagaaat ctcataatgc tcaaaacccg
    54121 ctcgctccag ctctgcaatg atgtactcaa acatctccgc ttctagttcc tccttaggca
    54181 gaggcaattt cccacgtcgc atccggttca taaagaccgt atggttttct aaaatcaaac
    54241 tatacaaact catgtgggga atatccagtc caatggcttt agccacattt tcctttactt
    54301 gctccatggt ctgaccaggc agagcataaa tcaaatcaat ggagatgttg tcaaaaccag
    54361 ccagtttcag gcgatcgata ttttcataaa tatccttctc caaatgactg cgcccaatct
    54421 ttttcaacat cttatcatca aaggtctgga cacctagcga aacacgattg acagccgaat
    54481 ttttcaaaac agctatctta tccgcatcca aatcgcctgg attggcttca atggtcaact
    54541 cttccaagac agacaagtcc aagtttttag tcaagccatt cagtaacacc tccagttgcg
    54601 gagccgacag ggctgtcggt gttccaccac cgatataaag ggttgacaac ttttcaatat
    54661 cataagaacg aaactcttcc agcagatgct ctaaatagct gtcgactggc tgatttttga
    54721 tgaagacctt tgaaaaatca caataataac aaatctgggt acaaaatggg atgtgcacat
    54781 aggctgacgt tggttttttc tgcatagtaa ttattatacc acaaagacta gattccagat
    54841 aaaaatcacc atccccagat acatagtccg tccggagatg gtgatggttt attcttctgt
    54901 tatatcaatc acaatctctt ctgagtcatc aagagcttcg gctttttctt gccattgctc
    54961 cttgagatta tttaattgat tttttgatgc ttctgtcgct tgaaaagcat aggatttagc
    55021 ttgagcaagt atactgtcca cagtgatttc acctgactca acctgttctt ttgttttcag
    55081 aacaaaatct gtagcctgct ccttaacttc tgtcagtttt tcacagactt gctccttggc
    55141 atactccgga tcttctctca aatcatctag aaaatcttga gcctgactgc aaacttgttt
    55201 gcccttatca cttgttaaaa acaaggcaag agctgcacct gaaacggttc ctaaaaggat
    55261 tgaggataat ttacccataa ggattctcct tttttatttt ttgaaaaatt tacttgcaag
    55321 acgaagagct gacagacttg caccagtctt gagtgttttt gaaccagctg atgaagcttt
    55381 cttgctcaag acacgcgcat ggtcattgag gtctgaaaca gatagagata aatctgcaac
    55441 agcactgaag agtggatcaa tcgtagccac cttgacattg atatcatctg ccaagacatt
    55501 gaccttagcc aacaactcat tggtgtgatg caaggtcaca tccacatctg aagtcaaggt
    55561 tttaatcgtc ttttctgttt catcgatgac acgaccaagc ttttgtacag taatgatcag
    55621 atagaccaaa aagacaatca aagctagggc aacaagaata tatgcaactt ctaacattta
    55681 gttttcctcc tctgtaatat agtaaggggc cttctttcga ttttgataaa taacgatcat
    55741 tataccgaga ccgataaaga caactgacag ccattgggac actcgaaggc tgaagaacat
    55801 gagactatct gttcgcatac cttcgatgac catacgaccg aaaccatacc aaatcaagta
    55861 aaaggccgtg atatgacctc gtctgagact cttccatttc cgtctaaaaa tcagaatcaa
    55921 ggcaaagcca agcagattcc atagagactc ataaaggaaa gtcggttgac ggtagctccc
    55981 ctcaatatac atctggtcac ggataaagcc aggtagataa tccagattat ccactgttgc
    56041 accataagct tcttggttaa agaaattacc ccaacgcccc aaactttgag caatcataac
    56101 gctaggcgcc gcaatatcta gaaaatccca agtattgatg agtttacggt cagcaaagat
    56161 atagagcaca agagccccag ttatcaaacc accgtaaatg gccaaaccac cattccaaat
    56221 ggcaaaaatc tctcctaaat tctgactata gtaatcaaat cggaaaataa catagtagag
    56281 acgagctcct aaaatagcca agggaaaggc tactaagata aaatctaaaa tatcgtctgg
    56341 tatgatcttc tttctaggtg cttctttcat ggtcaaataa accgcaagaa tcaagcctgt
    56401 cacaatacat aaggcatacc aacgaatggc taggggtcct agttgaatag caattggatc
    56461 aagcattttg cacctcattt cgagctatga gacttgtcag tcgttcgtcg aacaaacggg
    56521 tagcatcaaa gcccatttcc ttggcacgat aattcatggc agctgcctca atcacaacag
    56581 agatattacg acctgtttta actggaatac gaatacgagg aatggctacg ccagaaactt
    56641 caagttcctc tgcattgttt ccaagacgat caaaggtctt atgcgtatcg taattttcca
    56701 aatagacagc aagctgaacc tgtgaagaat ccttgacagc actcgcaccg tagagactca
    56761 taacatcgat aataccaacc ccacgaattt caatcaagtg tttcaaaatt tcagctggtt
    56821 caccccagag agtaatctca tccttggcaa agatatcgac acggtcatcg gctaccaaac
    56881 ggtgaccacg tttgacaagc tcaagacctg tctcgctctt accaattcca ctatctccct
    56941 gaatcaagac gcccatccca taaatatcca tcaagacacc gtgcacactg gtacgttctg
    57001 ccaaacgaga atccagatag ctagataact ctccagataa acgactggta gctgcacggc
    57061 tggttaaaat agcaatctta cattctctag cagcctttaa catctcctct ggaaccacca
    57121 aaccacgggc aacaatgact gctggtgtct caggtagaaa catttttttc aaaacttcat
    57181 aacggctgtt ggaaggcatg ctgatcagat aagaccactc cttcatcccc aaaagttgaa
    57241 tccgctctgg tgtatagtag tcaaaatagc ctgtcatttc aagaccaggt cgcgtaatat
    57301 ccgctgtatt gatttccttt tcaagcaatt ctggttcacc atagacaata tctagtctaa
    57361 gcttttcaat cacttctttt actaaaaccg acatcatttc ctccttcaaa tgaattcttc
    57421 tctctattat atcaaattgt aggaggaagt ttcagatttt tgcaggcttt ggagtattta
    57481 tttaaaagaa aaaggactag atttctctag cctttcattt caattagaat tttttacgtt
    57541 tacgagctac ttctgattta cgtttacgtt ttacagaagg tttttcatag aattcacgtt
    57601 tgcgtgtttc ttgaagagta ccagctttag taaccgcacg tttgaaacgg cgaagtgcgt
    57661 cgtcaagaga ttcattctta cgtactactg ttttagacat ttttttcact cccttcaagt
    57721 tcaatatcta tttcattcta cacgtaaaag gaataattgt caagcaaaaa tgcggtttaa
    57781 ttttgatttt ttcttccatt tatacaagag ttgaaagcgt tcaatagaac attgcttttt
    57841 tatttttcga gtaagctaag cgcttcagca tctgcgatga tggttacatc agggtgattt
    57901 tggaggctac ttgcaggtag gttctcagtc actgggccag atactgttcc ggcaatggct
    57961 tctgctttcg actcaccata agcaaaaaga ataatagact tggcatccaa aatgttttta
    58021 atccccattg aaatagcttg ggttgggacg tcttcaatct tggcaaagaa gcgagcattg
    58081 gcttcgatag tagactggtc aagttctact agatgcgttt gactgtcaaa tggagtacca
    58141 ggctcattaa agccgatatg cccattgcga ccgattccca agatttggag gtcaactgga
    58201 tggtcagcca aaatttggtt gtagcgttca acttcagctt cagcattgtc cttaacacca
    58261 cgaggcaaga aactttcttt aaatggtttt tggttgaaca agttttcttg catgaagtaa
    58321 cgataagact gtggattgtc cccatcaagg cccacatact catcaaggtt gacactggtt
    58381 agatttgaaa aatcaaggtc actctcaaca atttccttgt aaaattcaag tgggctactt
    58441 cctgtcgcaa gtcctagagt ttgagctcca ttagccaatt tttccttcaa aatctcaaaa
    58501 gcaacttttc caccttgaac ttggttttca actttaataa ctttcatctt ttcatcctcc
    58561 atttctgtct atatttatta tatggtatag accaattttt gtcaagtgaa aacgatttaa
    58621 tttctaaaaa aagagcgtcc aaacttgaaa cgtgttataa tggataggat tagaacttag
    58681 aaagaatgaa caaatatatg aatacagctg attttgattt ccacttgcca gaggaattga
    58741 ttgcccaaac gccccttgaa aaacgtgatg cctccaaact cctcatcgtc aaccgtgaga
    58801 caggagaaat gcaagataaa catttccact ctattattga tatgctggaa cctggtgatg
    58861 cccttgtcat gaacgacacc cgagttctcc ctgcccgcct ctatggtcaa aaagtggaga
    58921 caggaggtca tgtggaactt ctcctcctta agaacactag tggagacgag tgggaagttc
    58981 tggctaaacc tgccaaacgc ctcaaggtcg gtactcgtat cagctttggt gatggccgcc
    59041 tcagcgctgt cgttacagaa gaattgaccc acgggggacg cattgtccgc tttgaatacc
    59101 aaggaatttt cctagaagtc ttggaaagtc tgggagaaat gcctctgcca ccttatatcc
    59161 acgaaaaatt agatgaccgt gaacgttatc aaaccgtcta cgccaaggaa agcggctctg
    59221 ctgcagcacc gactgctggt cttcacttca ccaaagaact gctggcagaa atccaagcta
    59281 agggtgttca tctagtctat ctgactctcc atgtcggact cggaaccttt agacctgttt
    59341 ctgtggataa tctggacgaa cacgaaatgc actcagagtt ctatcaactt tctgaggaag
    59401 ctgctgccac ccttcgctct gtcaaagaaa atggtggtcg cgtcatcgct gtcggaacca
    59461 cttctatccg caccttggaa actattggtt ccaagtttga tgggcaaatc caagcagatt
    59521 ctggttggac caatatcttt atcaaacctg ggtatgagtg gaagatcgtg gatgccttct
    59581 caaccaactt ccatctgcca aaatcaactc tggtcatgtt ggtttctgcc tttgcaggcc
    59641 gtgaattagt cttagatgcc taccaccatg ccatccaaga acactaccgc ttcttcagtt
    59701 ttggtgacgc catgtttatt tattgagaaa gaatttctct aattcttcta ataccaataa
    59761 atcgctaaga tattatttca aagaacatct acaattgaaa ctctagctag ctgtagaaga
    59821 cgcctagtac attgaaatta aaatgcttcc ccctagcttc gaaaatattg ccatagattg
    59881 cgttgactct ccaaattgat tcatctatat tttatttcag cttcctatat tttcttcgct
    59941 gtttgtaaat caaaatgcaa gacacatgag tagcaccata tttgttactc ttatctgtcc
    60001 tctcaagaga ctattatgag ttatttcaga atcattcact actttgaccc tgactctcct
    60061 tagtctcaaa atcaaagact tatactcttc aaaaatctct tcaaaccgcg tcaacgtcac
    60121 cttggattat atatgtgact gacttcgtca gttctatcta caacctcaaa gcagtacttt
    60181 gagcaacctg cgactagttt tctagtttgc tctttgattt tcattgagta ttaaacaaaa
    60241 agtgaacaaa tctgaattct aatgtacaga agactaggct tgttcacttt tttatagtcg
    60301 ctataagatg accttatcta tagcttttta tatataatta tatattcaga catactatta
    60361 tcaattttgt cgcagggagg aatctgttaa cgcacccatt caccattatc attgactcta
    60421 tagccatcta tacttgtatt gaccgctaac tcacccgatg catttacata ataccattta
    60481 ccaccaactt ggaaccattg attgactttc atagaaccgt tgctgttgag gtagtaccat
    60541 gaaccattaa cttgtaccca acctgttgcc atggaaccat cagtattata aaaataccac
    60601 ataccatttt cttgtttcca gtctgttgtt ggagcaactg ctttagctgg ttctactgct
    60661 acatctgttc cttggttaga tgtaacagat acaggatacg aaggaataga tgattgctca
    60721 ggaacaacaa ctttttcagg ttctctcgtc cctctcctta tacgtctttt taccatctct
    60781 ttagtaattt gacgagaagt agtttcttca attattccat cacgttcatc tacagtatag
    60841 attgtagtaa gagtaattta ccaatttctc ctacttcttc tacttcttga cttttatcaa
    60901 gagttgggcc atcgagatat tctgtttcga ttggaatttc ttggacaaga acttggggct
    60961 tggttccttt tttaacaact cttgtttgag agtctttttt tgacttaaag tactctcagt
    61021 tacttgtcca ctctttccat ctacattata agttatcgtt gtaactgttt tcccattctt
    61081 tcctagagta atctcttgct cctgtcctgc agaaaggtca ttgtctgctt catatttagt
    61141 agcaaatgga acaagaactt cttcaatctt gcttttagct ggaactttga taactgtatc
    61201 cgtggcttct tttctatcaa cagtaacctg ttcggtaaca taaccagtct ctggattaac
    61261 atcgtaggtc cttgtcgtag ttacatagcc atcctctccg tcaattgtaa caggattttc
    61321 actacggtct tttgtttcat ctttttcaaa acgaattcgc gtacttgaaa ttttcttggt
    61381 tactacctta ggtttagtcg ctacttttac aataatatcc ccattgtcag cgtcatcata
    61441 ctctattccc tcttctttat ctctagtatc atctctgaca tattgaatcc catcagcagc
    61501 atgagcaaaa cttgtattca gattcctcct aaaaataaag ttagcccgat tatcgcagaa
    61561 ccaaaaatct ttccgagttt acgtattgca taacgcttat tagtattaga ttttgccatt
    61621 acatcctact tctagtatag catcttttct atcaaacgtt aaacaatata ctttatatat
    61681 aaaatagact tagaatgata tattgattat tgaactaaca ctttaactat atcgtaatca
    61741 atctcatata taaaggattg cagacatctg atctaaatac atgctaatat atttagatac
    61801 aaacattcca acttgataat tttcactcat ctttcaacat tccttacaca acgatgcagt
    61861 ataaatagaa tagttttctc atcagaatga gactatttta atattagata atttgataga
    61921 aaaacataaa taaaattggt tgaatttaat tccctaactc gatagaggat tctattttaa
    61981 atttaacaac agctaggatt acactataaa aagtacatta ccacctgttc ggctggagaa
    62041 tctagtcgat tagctccctc ttagttacaa gcttaaagcg attttttaac taatactaaa
    62101 ccagattaaa gaaggaacta gaacatctgt cttgtactaa tcaatatgct attttaaaat
    62161 tgcaaataaa cttggaatgc taattattat atttacaata aatagttgac ttcgatagaa
    62221 acagaaaata gaattcaaca ttcttcccta cttataccat aataaataag atccgcaaga
    62281 tagccttttc tctctacacc attaacaatg gtttgtagat aggacattcc agccttttcc
    62341 atgacacgac ctgaagctgg gttgagactg gcataacgtg ctctgacctt ttgaaaacct
    62401 gcttgagtaa aacaaaagtc caagacagct ttcaaggcct ctgtcatcat accatgtccc
    62461 cagtaagcct tgcctagcac atagccgatt tcacagctta aatcagcctc gtctatctta
    62521 acgatgctga tatctcctat cacttgctct gggttttctt ttagacaaat ggcccatttg
    62581 taatagttga gattagtata ggaagcaacc caattgcgaa tcgagtttcg agtgatttcg
    62641 acatcaggat ggggatccca ggtaacatag gtcagattct cagtggatga agcccaattt
    62701 tgaaacatgg cttctgcatc actctccaca aatcttctta aaatcaaacg ttctgtctgt
    62761 aatatttgcg taccgataga tttcatgatg ctacctcact tccttatttc tatactcgta
    62821 gtaagaaggc tcaactcagt aacagctaga aaacgagttt gtcttctaat ttcttgacgc
    62881 agttgctgcc tggtttgaaa tgcgctctag caagcttttt caaacctagt catcgttgca
    62941 ggggtaagac gatgaaatcg aactcttcga gttactgaat ctgcctcatt ttcttatttc
    63001 taaactcggg gttcaagatc ccccagacct tctctcactt tcttatttca agatgagagg
    63061 ctgaaaacct ccactggagg tttttcttgc tttttaattt cagggcaaga agctaaaaag
    63121 gtcccccgga ccttcttcgc tttctcattt ctaggctcag ggtaaaaacc tccagtggag
    63181 gtttttactc ccaaaagtca tcaaatacag tgatgggtaa gtggcgtttg tgttggcctt
    63241 tgtgccacca gttttcaatg gtcgcttgag cttctgggct gattgttttg ccttctaggt
    63301 agtcgtcaat ctctgcgtag gtgactccaa gtgcgacttc gtcagctagg cctggtttat
    63361 cttcttctag gtctgccgtt gggatttttt cataaagggc tggctctgcg ccaagtttct
    63421 gcaagagctg ttttccttgg cgtttattga ggcggtaaag agggagaata tccgcaccgc
    63481 cgtcaccaaa cttggtaaag aaacctgtga tattttccgc ggcgtggtct gttccaatga
    63541 ccgctccgct atgggaacca gcaagggcat actgagcaat catacggcaa cgtgccttga
    63601 tattcccctt gttgaagtct gaaacaggac tacctgtcgc ttcaactgca gctgtcatgg
    63661 catcagctga ttccttgata ttcacaacca agctgacatc tggctggatg aaggctaggg
    63721 ctttttgagc atctgcttca tcagcttgca ctccgtatgg caggcggaca gcgataaatt
    63781 tgtagctatc gtctcccgtt tcagctcgca gttcttccat agctaattgc gccaaacgtc
    63841 ctgccaaggt tgagtcttgt cccccagaaa tccctagtac aaaggttttt aggaagggat
    63901 gttttttcag atatcttttt aagaaatcaa tagaacgacg gatttcttcc tgggcatcaa
    63961 tcactggttt gacacccagc tcttggataa tcgtttcttg caaactcatt cttcttctcc
    64021 ttcaccaagg gcttccttgc gcatcttatc aatcaagtcc atcttatctt gccatacatc
    64081 acgcgccaaa tccactggat agtgctgcgg attgagcaca cgcttatact catcccacaa
    64141 cttgtcaaat tccttacggg cataatcctg aatgtcagtc aaactaggca agttgtaaac
    64201 taatattcct tctttgaaga tatccaccaa gagaggaacg gcatcaaaat tacgaaccgt
    64261 cttcttgatg tatgtatagg tcggatggaa catcttgatt tctgtcatgt cgctaatatc
    64321 cacaccatca taagtgatgt agtcaccttc tgacttgcct ttttcacgac tggtaatgcg
    64381 ccacacctgc ttcttacctg gcgtcgacac tttttccgca ttattagaca gcttaatcgt
    64441 attgcgcatc tggccgtttt catcttcgat tgcaacaatc ttgtaaaccg ccccaagagc
    64501 cggctggtca taggctgtaa tcagcttggt acccacaccc cagacatcaa tcttggcctt
    64561 ttgcatcttg aggttaagga tggtattttc atctagatca ttagaagcat aaatcttagc
    64621 ctctggaaat ccagcctcgt ccagttgctg acggactttc ttagaaatgt aggcaatatc
    64681 cccagagtca atccgcacac ccataaagtt aatctgatca cccagctcac gcgccacctg
    64741 aatggcagct ggtacaccga tgcgaagggt atcataggta tccacaagaa agacacaatt
    64801 tttgtgggtc gcagcgtaag ccttgaaagc ctcatagtca ttgccataaa cctgtaccaa
    64861 ggcatgggca tgggttccca aaacaggaat gtcaaagagc ttacccgcac gcacgttgct
    64921 ggttccattg gcgccaccaa tcaccgctgc gcgtgttccc cagatggccg catccatttc
    64981 ttgagcccga cgtgtcccaa actccatcaa gggttcatct tcgataaccg aacgaatacg
    65041 agctgccttc gtcgccacca aggtctggta gttgacgatg ttcaaaagag ccgtttcgac
    65101 caactgacat tgggctagag gtccttccac ctgcacaatc ggttcattag caaaaaccaa
    65161 atccccttct tgggcagaac gaacggtcaa ctccaacttg aaattgcgaa ggtaatccaa
    65221 gaacgcccca tgataaccaa gcgactccaa ataggctata tcactatctg aaaaacgcaa
    65281 gtcttcaaga tagttcacaa ttctttccaa acctgcaaaa accgcatagc cgttcttaaa
    65341 aggctgttgg cggaaataca cctcaaagac cgccttctta ttgtaaatcc cttgatcaaa
    65401 gtaaacctgc atcatgttga tctggtacaa gtccgtgtgc aatgtcaaac tatcatctgg
    65461 atacatactt ttcctacttc cttagctaga aacccatgaa aattttcaag aactttcatg
    65521 tattccaata aattagtact attatatcac attttagctg gattgagaaa agagtaacaa
    65581 gctattctcc actctccaat tcatccatat cttgttcaaa ttttttctga gcccattcgc
    65641 catagctctt aagaccaaga ttgccaataa agacccacgg aaggtaaatg acataagtaa
    65701 tgacccaagc agacaggtat ttaaaattca aaggattgtg ctgataaatt tctatgttga
    65761 attgataatt ctgcaacatc aaaagagccg taatagccaa ggttaggaaa aaacaaccca
    65821 aaatcgtaaa atgaaaacga ctatagtagg tcactcccag ataacgggca cgattgaaaa
    65881 agtaaaatgt ccctatgatg ataacgatta gcagcatatt agaattaaaa aggcttggtg
    65941 ctaatactga aatgatataa gataggagcg acaaagcaat gcagatatag aaactttcag
    66001 agcccgcttt attgaacagt tgttcttctc tttcgtctag taattgataa taataaaatc
    66061 tatttttcat cttcttcctc ccaaaatagt tggtctaggg ttttccctaa acatctgcaa
    66121 atagactggc agagcgagag actgggattg tattttcccg cctctatcaa accaatagtc
    66181 tggcgtgtca ccccgacagc ctctgccagt tgaccttgtg ttaaatcacg ctctacccga
    66241 gctaatttta attttaaatt tttagccacc ttcgtcctcc ttatagtttt aatactcatc
    66301 tactcttaaa aaatccaaaa ccaacacaag ctatcagcta tttattataa ccccattaat
    66361 ttgcactcca gtattatctt cagccgaaaa tcagtatttt aggttgtttg aaataaactt
    66421 cctagtttac tcttttattt ttatttagta ttagctttag taggatcttt taaacgagtt
    66481 tttattgctt atatttcttg tttagtttag ttggtttcat atcactatta tataatgctt
    66541 ttggaaatga gcctagtata agtcaaaaac gtgttgaata gtgaaagcag gagcatacca
    66601 agatgactga ttttttactg tattttaggt atgcaaaata atactaaatg aaactaaaat
    66661 gaatacttct tgcttttctt gagagtgaaa aagtacaata aaatgattgt agtgattagc
    66721 acaagatact gactaataga catcgtattt gaagccacaa atacaggtaa agaataaaaa
    66781 ggaagaagtt caattgcttt gataaacaaa tcattactag tattcatcat catcgtattt
    66841 aatatattag ggataaagag tagtaaagct actaaaatac caaataccaa gccacttttc
    66901 aatttgtata aatagaaaat gtaggataat agaaaataaa acaggactaa caaaattgta
    66961 ttgactacaa tagctactat aaaatctaat cctaaatcac ctggaatacc caatttactt
    67021 actatgacta gtaacacaat gccattccaa gcataaataa tggaaactga gatggcatat
    67081 agaaaattag acaagacgta aatcatccga ttcttctgtt gattataaaa caaacttacc
    67141 gtattgtggg aaaaatctct actaatgact cgattagcat gtataacagc cattaacata
    67201 ccgagcatgg cataaaagtt tgaaatatgc ttaataccaa gcgatgtccc ttgagtcttt
    67261 agaataaaga atgtaagcaa tatcggcggt ataaacgaga taagcaaact gagatatatt
    67321 acgcctgatg aatataaatt tcttatactt tccttaagaa aattcaattt atttaatttc
    67381 atgattataa ccttccttta ttttgaacga tttaggtaaa tatctttaag cgtctctttt
    67441 ttagtttcaa aatcaactac tttaatagag ttttcgttaa aaaatttaaa aagctcacta
    67501 ctttgaatat tcccagacat agtaattctc agtccctctt cctgaacaat atctccaaat
    67561 tcttgtttgg taatgaaaat gtctctatct gtagctgatg aaaaagctat ctcaaacaag
    67621 aaattatgac tatcttttcc tactttttga aatgtcaaaa gcccgctctc caagaaaaga
    67681 accctctcac aaatttcttc aatatcttct aatttatgac tcgatattaa aattcccaca
    67741 ttttcatgta aagctaaatt ttttagaacc gctaaaacta tttgtgatga ttcaatatct
    67801 aaaccattag tcggttcatc taaaatcaat atatcaggtt ccgtaacgag agttagaagc
    67861 aaagctaatt tttgttttgt acccaaagaa taggtcttta cttttttatt aatagactga
    67921 gtcaaatcta actcttggat caaacttcta aatctttctt gattgtagtc aacaccatat
    67981 aaatttgaca aatattttaa attctctaaa cctgttttag ataaaaataa ttttggttct
    68041 tcgattaaat acccaatatt atcactgctt ataatattac ctgaagtcgg ttgattattc
    68101 tgagcaagaa ttttcatcaa catactctta ccaactccat ttctccctac tagaccaaca
    68161 atttcaccct tgttaagtgc aaaatttatg tctttgagaa tgattgaatg accataatgc
    68221 ttacttacat ttataactta cattttttat tcctccatta atattcatgg tttgctcttt
    68281 gattcttatt gagtttaaaa agttgcgcct ctttttaaca acattatatc atatatctaa
    68341 cttaatgcaa tatataaata tcattttgta aaattttatt aacaaaaaac tctctacaac
    68401 aaaataatag agagttttct gcttattaat ttttttcaaa atatctaaga catcacttct
    68461 ttgtttaatt tgataggctt tgatacctaa gctccgactt tatcacttaa aaaataaaaa
    68521 aggacagcta atctcttgcg catcaaggga tttcgccatt ctttaatctc gtttaagtgt
    68581 tgtatatgga gctttgcata attttttaaa actaaacaac tacattaagc acgaactgtg
    68641 acgctggttc catcttcctt ataaa
//
LOCUS       DAYYYC010000003        61054 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.003, whole genome shotgun sequence.
ACCESSION   DAYYYC010000003 DAYYYC010000000
VERSION     DAYYYC010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 61054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.003"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(67..1047)
                     /gene="dusB"
                     /locus_tag="ACHBV5_000187"
     CDS             complement(67..1047)
                     /gene="dusB"
                     /locus_tag="ACHBV5_000187"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFM9966062.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1034..1906)
                     /gene="hslO"
                     /locus_tag="ACHBV5_000188"
     CDS             complement(1034..1906)
                     /gene="hslO"
                     /locus_tag="ACHBV5_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFM9966063.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2071..3498
                     /locus_tag="ACHBV5_000189"
     CDS             2071..3498
                     /locus_tag="ACHBV5_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM9966064.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3657..5165
                     /gene="glpK"
                     /locus_tag="ACHBV5_000190"
     CDS             3657..5165
                     /gene="glpK"
                     /locus_tag="ACHBV5_000190"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFM9966065.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5207..7033
                     /gene="glpO"
                     /locus_tag="ACHBV5_000191"
     CDS             5207..7033
                     /gene="glpO"
                     /locus_tag="ACHBV5_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFM9966066.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7103..7807
                     /locus_tag="ACHBV5_000192"
     CDS             7103..7807
                     /locus_tag="ACHBV5_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFM9966067.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8104..8307
                     /locus_tag="ACHBV5_000193"
     CDS             8104..8307
                     /locus_tag="ACHBV5_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966068.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(8394..9002)
                     /locus_tag="ACHBV5_000194"
     CDS             complement(8394..9002)
                     /locus_tag="ACHBV5_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966069.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            9134..9331
                     /locus_tag="ACHBV5_000195"
     CDS             9134..9331
                     /locus_tag="ACHBV5_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966070.1"
                     /translation="MLNAKIFYIFLCLIVIETTGLLLLKRGLEMGYLDTEAIILAVFS
                     FAFYNLCSFAWVCSTIKNNKK"
     gene            10149..11425
                     /gene="ltrA"
                     /locus_tag="ACHBV5_000196"
                     /pseudo
     CDS             10149..11425
                     /gene="ltrA"
                     /locus_tag="ACHBV5_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            11877..13055
                     /locus_tag="ACHBV5_000197"
     CDS             11877..13055
                     /locus_tag="ACHBV5_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ryptide export MFS transporter"
                     /protein_id="HFM9966071.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTCINLVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            13369..13500
                     /locus_tag="ACHBV5_000198"
     CDS             13369..13500
                     /locus_tag="ACHBV5_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFM9966072.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            13521..15071
                     /gene="dltA"
                     /locus_tag="ACHBV5_000199"
     CDS             13521..15071
                     /gene="dltA"
                     /locus_tag="ACHBV5_000199"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFM9966073.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            15068..16312
                     /gene="dltB"
                     /locus_tag="ACHBV5_000200"
     CDS             15068..16312
                     /gene="dltB"
                     /locus_tag="ACHBV5_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFM9966074.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQTIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            16326..16565
                     /gene="dltC"
                     /locus_tag="ACHBV5_000201"
     CDS             16326..16565
                     /gene="dltC"
                     /locus_tag="ACHBV5_000201"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFM9966075.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            16558..17826
                     /gene="dltD"
                     /locus_tag="ACHBV5_000202"
     CDS             16558..17826
                     /gene="dltD"
                     /locus_tag="ACHBV5_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFM9966076.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            17981..18421
                     /gene="adcR"
                     /locus_tag="ACHBV5_000203"
     CDS             17981..18421
                     /gene="adcR"
                     /locus_tag="ACHBV5_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HFM9966077.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            18421..19125
                     /locus_tag="ACHBV5_000204"
     CDS             18421..19125
                     /locus_tag="ACHBV5_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFM9966078.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            19118..19924
                     /locus_tag="ACHBV5_000205"
     CDS             19118..19924
                     /locus_tag="ACHBV5_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFM9966079.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            19934..21439
                     /gene="adcA"
                     /locus_tag="ACHBV5_000206"
     CDS             19934..21439
                     /gene="adcA"
                     /locus_tag="ACHBV5_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HFM9966080.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(22610..23383)
                     /locus_tag="ACHBV5_000207"
     CDS             complement(22610..23383)
                     /locus_tag="ACHBV5_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFM9966081.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            23559..24962
                     /locus_tag="ACHBV5_000208"
     CDS             23559..24962
                     /locus_tag="ACHBV5_000208"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase family protein"
                     /protein_id="HFM9966082.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDVDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELNSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            25077..25715
                     /locus_tag="ACHBV5_000209"
     CDS             25077..25715
                     /locus_tag="ACHBV5_000209"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HFM9966083.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            25727..26167
                     /locus_tag="ACHBV5_000210"
     CDS             25727..26167
                     /locus_tag="ACHBV5_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HFM9966084.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            26160..26591
                     /locus_tag="ACHBV5_000211"
     CDS             26160..26591
                     /locus_tag="ACHBV5_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFM9966085.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            26582..27052
                     /locus_tag="ACHBV5_000212"
     CDS             26582..27052
                     /locus_tag="ACHBV5_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM9966086.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            27077..27850
                     /locus_tag="ACHBV5_000213"
     CDS             27077..27850
                     /locus_tag="ACHBV5_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFM9966087.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            27847..28647
                     /locus_tag="ACHBV5_000214"
     CDS             27847..28647
                     /locus_tag="ACHBV5_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFM9966088.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            28706..31000
                     /locus_tag="ACHBV5_000215"
     CDS             28706..31000
                     /locus_tag="ACHBV5_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HFM9966089.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRV
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            31010..34126
                     /locus_tag="ACHBV5_000216"
     CDS             31010..34126
                     /locus_tag="ACHBV5_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 98 C-terminal
                     domain-containing protein"
                     /protein_id="HFM9966090.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            34183..35949
                     /locus_tag="ACHBV5_000217"
     CDS             34183..35949
                     /locus_tag="ACHBV5_000217"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HFM9966091.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            36095..37246
                     /locus_tag="ACHBV5_000218"
     CDS             36095..37246
                     /locus_tag="ACHBV5_000218"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HFM9966092.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            37391..38275
                     /locus_tag="ACHBV5_000219"
     CDS             37391..38275
                     /locus_tag="ACHBV5_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFM9966093.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(38312..38470)
                     /locus_tag="ACHBV5_000220"
     CDS             complement(38312..38470)
                     /locus_tag="ACHBV5_000220"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966094.1"
                     /translation="MKIKEQTRKLATGCSKHRFEVVDKTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            38674..38925
                     /locus_tag="ACHBV5_000221"
     CDS             38674..38925
                     /locus_tag="ACHBV5_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HFM9966095.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFDGMGDQPVQDTE
                     TSSALILSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            38913..39203
                     /locus_tag="ACHBV5_000222"
     CDS             38913..39203
                     /locus_tag="ACHBV5_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HFM9966096.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(39412..39495)
                     /locus_tag="ACHBV5_000223"
                     /pseudo
     CDS             complement(39412..39495)
                     /locus_tag="ACHBV5_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(39590..40921)
                     /locus_tag="ACHBV5_000224"
     CDS             complement(39590..40921)
                     /locus_tag="ACHBV5_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HFM9966097.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEENLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(40943..42454)
                     /locus_tag="ACHBV5_000225"
     CDS             complement(40943..42454)
                     /locus_tag="ACHBV5_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFM9966098.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(42665..43612)
                     /gene="arcC"
                     /locus_tag="ACHBV5_000226"
     CDS             complement(42665..43612)
                     /gene="arcC"
                     /locus_tag="ACHBV5_000226"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFM9966099.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(43777..44793)
                     /gene="argF"
                     /locus_tag="ACHBV5_000227"
     CDS             complement(43777..44793)
                     /gene="argF"
                     /locus_tag="ACHBV5_000227"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFM9966100.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(44851..46080)
                     /gene="arcA"
                     /locus_tag="ACHBV5_000228"
     CDS             complement(44851..46080)
                     /gene="arcA"
                     /locus_tag="ACHBV5_000228"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HFM9966101.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            46835..48514
                     /locus_tag="ACHBV5_000229"
     CDS             46835..48514
                     /locus_tag="ACHBV5_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HFM9966102.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGSNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGACLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKT
                     PRLSQTVAVQGLAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(48554..50638)
                     /locus_tag="ACHBV5_000230"
     CDS             complement(48554..50638)
                     /locus_tag="ACHBV5_000230"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HFM9966103.1"
                     /translation="MKPLLETIDTRFGTASKHAFSWGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHATDELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKASAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            50809..52089
                     /locus_tag="ACHBV5_000231"
     CDS             50809..52089
                     /locus_tag="ACHBV5_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFM9966104.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKNFLLDQLVACDGGTGLMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            52180..54825
                     /locus_tag="ACHBV5_000232"
     CDS             52180..54825
                     /locus_tag="ACHBV5_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFM9966105.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            54909..55778
                     /locus_tag="ACHBV5_000233"
     CDS             54909..55778
                     /locus_tag="ACHBV5_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFM9966106.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            55772..57652
                     /locus_tag="ACHBV5_000234"
     CDS             55772..57652
                     /locus_tag="ACHBV5_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HFM9966107.1"
                     /translation="MVRFIGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRHDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            57979..58305
                     /locus_tag="ACHBV5_000235"
     CDS             57979..58305
                     /locus_tag="ACHBV5_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966108.1"
                     /translation="MILWSFDFANDHAHAFFMDNIEWSHADSYFLSFVSDDVEERYTE
                     NVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSVGTSPEQYPDYDG
                     FDYEEW"
     gene            complement(58357..59206)
                     /locus_tag="ACHBV5_000236"
                     /pseudo
     CDS             complement(58357..59206)
                     /locus_tag="ACHBV5_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(59151..59333)
                     /locus_tag="ACHBV5_000237"
     CDS             complement(59151..59333)
                     /locus_tag="ACHBV5_000237"
                     /inference="COORDINATES: protein motif:HMM:NF016232.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM9966109.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            59668..>61054
                     /gene="pcpA"
                     /locus_tag="ACHBV5_000238"
     CDS             59668..>61054
                     /gene="pcpA"
                     /locus_tag="ACHBV5_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HFM9966110.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNRGV"
BASE COUNT        18512 a        11129 c        13310 g        18103 t
ORIGIN      
        1 ttttttgatg aggaaagaat ggcggcattc aagaggctct ttaagagagt tacgggtttt
       61 aaactattaa gccttctcca attgcaagag ggcttcaatc tctgccaggg tgctagcttg
      121 cgaaatggct ccacggagtt tggcagcgcc agatgttcca cggaggtagt gaggagcgag
      181 gccgcggaat tcacgaactg cgacgttttc tcctttgagg ttaatcaatc gtttcaagtg
      241 ttcgtaggcg atcttcatct tgtcttcaaa ggtcaaatca ggtaggattt ctcctgtttc
      301 aaagtaatgg ttgatttggt tgaagaggta aggatttccc atggcagctc ggccaatcat
      361 gactgcgtca gcaccaactt cttcgatgcg ttgcttggct tcttggacag tacggatatc
      421 accgttggcg atgaatggaa tcttggttag agcttgggca accttgtaaa gggtctcaag
      481 gtctgcgtgg ccagtataca tttgttcacg ggtacggcca tgcatggcga gggcagaaac
      541 acctgcagcc tcagcagcga gggcattttc tactgccaga gatgggtccg cccagccggt
      601 acgcattttg acagtaagtg ggatatcaag gacagactgg accttgttga tgatagagta
      661 gatcttgtca ggatccttga gccacatagc tccagcttcg ttcttcacga ttttgttgac
      721 agggcagccc atgttgatat cgacgatatc ggtcttggtg ttttcttgga tgaattctgc
      781 tgcgcgtgct aggctgtctt catcgctacc aaaaagttgg atagagacag ggttttcgcc
      841 ctcatcgata tgaagcatgt gcagggtttt ttcgttgttg tattggattc ccttgtcaga
      901 gaccatttcc attacaacga gtccagctcc gagctctttt gcgatggtac gaaaggctga
      961 gttggtcacg ccagccatag gcgctaaaac ggtacgattg ggaatctcaa tattgccaat
     1021 cataaaaggt gtattaagat ttgtcacgaa tgagttcctc caggtccttt tcatcaaagt
     1081 tgtaagtagt ttggcagaat tgacaagtga tttctgcccc gtggtcttcc tctttcattt
     1141 cctgtaagtc tgagcttgga aggctggcaa gagcgttcat aaagcgttca tggctacagt
     1201 cacattggaa acggatttct tcttcagaaa gacgcttgta ggcttcgtcc ccgtagatag
     1261 ccttgaggag ggcttcgata tggtcgtcgc tttcgagaag agtagagata gctggcattt
     1321 cttggatgcg tttttcaaag cgagcaatct cttctttctt ggctcctggc aagacttgaa
     1381 ctaggaaacc acctgcaacc ttgaccttgt cttcctcgtc caaaaggaca ttgaggccga
     1441 ccgctgaagg cgtttgttgg ctttcagtaa ggtaaaaggc aaggtcttca ccgatttctc
     1501 cagagatgag gggagttata gagttgtaag gatttccagc accgtagtct gtgataacga
     1561 ggaattgacc atttccaaca aaaggtccga ctaggacttc accagtcgca gtctttttga
     1621 tgtcaacacc aggattttga acatagcctt tgacgttccc cttggtatca gcgacggtga
     1681 taatagcacc tagagagcta gagcccaaca ccttaactgt aagtttggta tttccttttt
     1741 cattggctgc gagaatctgg ctggcgataa gagttcgacc aagcgctaca gttgagctag
     1801 cttgggtttg atgtttttct tgagcagtgc ggacggtttc cgtgctatca aggacaaaag
     1861 cacgaaaggc tccgctttct gatatagttt taataatttt atccatagct actattttag
     1921 cataaaaatg cccaaagggg gagccgtgtg tttactgatt ttcaggataa tggaccagga
     1981 aatcagcatg aaaataaaaa gagaaacaga ttatttcagc atttgtaaga tttatgctat
     2041 gcttaaggta gaaaatgaaa ggggtaacaa atgtatttag gagatttgat ggagaaagcc
     2101 gagtgtggtc aattttcaat cctttccttt ctattacaag agtctcagac gaccgtcaag
     2161 gctgtaatgg aagaaacagg attttcaaaa gcaaccctaa ccaaatatgt caccctgctc
     2221 aatgacaagg ctttggatag tggcttagag ctggctattc actcagaaga tgaaaatctg
     2281 cgtctgtcta tcggtgcagc taccaagggg agagatattc ggagcttgtt tttggagagt
     2341 gctgttaaat accagatttt ggtttatctt ctctaccacc aacagttttt agcccatcag
     2401 ctggctcaag aattggtgat tagcgaggct acgcttggtc gtcacttggc tggtttaaat
     2461 cagattttgt cagaatttga tttatccatc caaaatggac gttggcgagg tccagagcat
     2521 cagattcgct atttctattt ctgtcttttc cgaaaggtct ggtcgagtca ggaatgggaa
     2581 ggtcacatgc agaaaccaga gagaaaacag gagattgcca atttagagga aatctgcggt
     2641 gcaagtttgt ctgtggggca gaaattggac ttggttctct gggctcacat cagtcaacaa
     2701 cgtcttcggg tcaatgcttg tcagtttcaa gtcatagaag agaaaatgcg agggtatttt
     2761 gacaatattt tctaccttcg tttgctgaga aaggttccgt ccttttttgc tgggcaacat
     2821 attccactag gagttgagga tggtgagatg atgatattct tctcttttct cctatctcat
     2881 cgcattcttc ctcttcatac tatggagtat attcttggtt ttggagggca gttggcagat
     2941 ttactgacgc aattgattca agaaatgaag aaggaggaac tattggggga ttatacagag
     3001 gaccatgtca cctatgaact cagtcagctt tgtgctcaag tctatctcta taagggctat
     3061 attttacagg atcgctacaa gtaccagtta gagaatcgtc atccatattt actgatggaa
     3121 catgatttta aagagacagc agaggagatt tttcatgctc tacctgcttt tcaacagggg
     3181 acagatttag ataagaagat tctctgggaa tggctccagt taatcgaata tatggctgaa
     3241 aacggtggcc agcatatgcg gattggtctg gatttgacat ctggttttct tgtcttttca
     3301 aggatggcag ccattttgaa acggtatttg gaatacaatc gttttattac cattgaagct
     3361 tatgacccta gtcggcatta tgatttgctg gttaccaata acccgattca taagaaggaa
     3421 cagacaccag tctattattt aaaaaacgac ttggatatgg aagatttggc agggattcgt
     3481 cagttattat tcacttaaaa ggcttggtta atccaggtct tttttgtgaa attcacacaa
     3541 tctcctcaca tttttttaaa aattaaaaaa agttgataaa caagaaagcg ctttattttg
     3601 tatactagta agtgtaaaga ggaaacacct caagatcttt atcaggagga cagtacatgt
     3661 cacaagaaaa atacatcatg gccattgacc agggaactac aagttctcgt gccatcattt
     3721 tcaacaaaaa aggggaaaag gttagctcga gtcaaaaaga gtttacccag attttccctc
     3781 aggcaggttg ggttgagcac aatgccaatg aaatttggaa ctctgttcag tcagttattg
     3841 cgggtgcttt catcgaaagt ggtgtcaagc caaatcaaat cgaggcaatc gggattacca
     3901 accaacgtga aacaacggtt gtctgggata agaaaacagg acttcctatc tacaatgcta
     3961 tcgtttggca gtcacgccag acagcacctt tggctgagca actaaaaagc caaggttatg
     4021 tggaaaaatt ccatgaaaag actggtttga ttattgatgc ttacttctct gctaccaagg
     4081 ttcgttggat tttggatcat gtagaaggtg ctcaagagcg agcagaaaaa ggggaattgc
     4141 tctttggtac tatcgatact tggttggttt ggaaattgac tgacggtgcg gctcacgtga
     4201 ctgactactc aaatgcagct cgtaccatgc tttataacat taaagaactc aaatgggatg
     4261 atgagatttt ggaaatcctt aacattccga aggctatact tccagaagtt cgttctaact
     4321 ccgaaatcta cggcaagaca gctccattcc atttctacgg tggagaggtg ccaatctcag
     4381 gtatggctgg ggaccaacaa gcagccctct ttggacagtt ggcttttgag ccaggtatgg
     4441 ttaagaatac ttatggaaca ggctctttca tcatcatgaa tactggggaa gagatgcagt
     4501 tgtctgaaaa caacctcttg acaaccattg gttacggaat caacggtaag gtttattatg
     4561 ccttggaagg ttctatcttc atcgcaggaa gtgctattca gtggcttcgt gacggtcttc
     4621 gcatggttga aaattcacca gaatctgaaa aatacgctcg tgattctcac aacaacgatg
     4681 aagtttatgt cgttccagcc tttacaggtc taggcgctcc atactggaac caaaatgctc
     4741 gtggttccgt ctttggtttg actcgtggaa caagcaaaga agactttatc aaggcgactt
     4801 tgcaatctat tgcttatcaa gtgcgtgaca tcatcgacac catgcaagtg gatactcaga
     4861 ccgccattca agtactgaag gtggatggtg gtgcagccat gaacaacttc ctcatgcagt
     4921 tccaggcgga tattttaggc attgatattg cacgtgctaa aaacttggaa acaacagctc
     4981 taggagcggc cttcctagca ggtttatcag tagggtattg gaaagacttg gacgagttga
     5041 aactcttgaa cgagacagga gaactctttg agccatctat gaacgaatct cgcaaggaac
     5101 aactctacaa gggctggaag aaggctgtga aagcaactca agtctttgcg gaagtagacg
     5161 actaatactg gcagaataaa gcgatttatt tagaaagtgt gtaaatatgg aattttcaaa
     5221 gaaaacacgt gaattgtcaa ttaaaaaaat gcaggaacgc accctggacc tcttgattat
     5281 cggtggagga atcacaggag ctggtgtagc cttgcaggcg gcagctagcg gtcttgagac
     5341 tggtttgatt gaaatgcaag actttgcaga aggaacatct agtcgttcaa caaaattggt
     5401 tcacggagga cttcgttacc tcaaacaatt tgacgtagaa gtggtctcag atacggtttc
     5461 tgaacgtgca gtggttcaac aaatcgctcc acacattcca aaaccagacc caatgctctt
     5521 accagtttac gatgaagatg gagcaacctt tagcctcttc cgtctcaaag tagccatgga
     5581 cttgtacgac cttttggcag gtgttagcaa cacaccaact gcgaacaagg ttttgagcaa
     5641 gaaagaagtc ttggaacgcc agccaaactt gaagaaggaa ggcttggtag gaggtggagt
     5701 gtatcttgac ttccgtaaca acgatgcgcg tctcgtgatt gaaaacatca aacgtgccaa
     5761 ccaagacggt gccctcattg ccaaccacgt gaaggcagaa ggcttcctct ttgacgaaag
     5821 tggcaagatt acaggtgttg tagctcgtga tctcttgaca gaccaagtat ttgaaatcaa
     5881 ggcccgtctg gttattaata caacaggtcc ttggagtgat aaagtacgta atttgtctaa
     5941 taagggaacg caattctcac aaatgcgccc aactaaggga gttcacttgg tagtggattc
     6001 aagcaaaatc aaggtttcac agccagttta cttcgacaca ggtttgggtg acggtcgtat
     6061 ggtctttgtt ctcccacgtg aaaacaagac ttactttggt acaactgata cagactacac
     6121 aggtgatttg gagcatccaa aagtaactca agaagatgta gattatctac ttggcattgt
     6181 caacaaccgc tttccagaat ccaacatcac cattgatgat atcgaaagca gctgggcagg
     6241 tcttcgtcca ttgattgcag ggaacagtgc ctctgactat aatggtggaa ataacggtac
     6301 catcagtgat gaaagctttg acaacttgat tgcgactgtt gaatcttatc tctccaaaga
     6361 aaaaacacgt gaagatgttg agtctgctgt cagcaagctt gaaagtagca catctgagaa
     6421 atatttggat ccatctgcag tttctcgtgg gtctagcttg gaccgtgatg acaatggtct
     6481 tttgactctt gctggcggta aaatcacaga ctaccgtaag atggctgaag gagctatgga
     6541 gcgcgtggtt gacatcctca aagcagaatt tgaccgtagc tttaaattga tcaattctaa
     6601 aacttaccct gtttcaggtg gagaattgaa cccagcaaat gtggattcag aaatcgaagc
     6661 ctttgcgcaa cttggagtat cacgtggttt ggatagcaag gaagctcact atctggcaaa
     6721 tctttacggt tcaaatgcac cgaaagtctt tgcacttgct cacagcttgg aacaagcgcc
     6781 aggactcagc ttggcagata ccttgtccct tcactatgca atgcgcaacg agttggctct
     6841 tagcccagtt gacttccttc ttcgtcgtac caaccatatg ctctttatgc gtgatagctt
     6901 ggatagcatc gttgagccag ttttggatga aatgggacga ttctatgact ggacagaaga
     6961 agaaaaagca acttaccgtg ctgatgtcga agcagctctc gctaacaacg atttagcaga
     7021 attaaaaaat taagaaaaaa taaaagaggt ggagggcagc attccttgtc gcccgtccct
     7081 tctttttaat ggagacagaa agatgatgaa tgaattattt ggagaatttc tagggacttt
     7141 aatcctgatt cttctaggaa atggtgttgt tgcaggtgtg gttcttccta aaaccaagag
     7201 caatagctca ggttggattg tgattactat gggttggggg attgcagttg cggttgcagt
     7261 ctttgtatct ggcaagctca gtccagctca tttaaatcca gctgtgacag ttggtgtagc
     7321 tttaaaaggt gacttgcctt gggcttccgt tttgccttat atcttagccc agttcgcagg
     7381 ggccatgctg ggtcagattt tggtttggtt gcaattcaaa cctcactatg aggcagaaga
     7441 aaatgcaggc aatatcctgg caaccttcag tactggacca gccatcaagg atactgtatc
     7501 aaacttgatt agcgaaatcc ttggaacctt tgttttggtg ttgacaatct ttgctttggg
     7561 tctttacgat tttcaggcag gtatcggaac ctttgcagtg ggaactttga ttgtcggtat
     7621 cggtctatca ctaggtggga caacaggtta tgccttgaac ccagctcgtg accttggacc
     7681 tcgtatcatg cacagcatct tgccaattcc aaacaaggga gacggagact ggtcttacgc
     7741 ttggattcct gttgtaggcc ctgttatcgg agcagccttg gcagtgcttg tattctcact
     7801 tttctagttt atactcttcg aaaatcaaat tcaaaccacg tcagcgtcgc cttaccgtac
     7861 tcaagtacag cttgcggcta gcttcctagt ttgctctttg attttcattg agtattagaa
     7921 aacaattatg ttgatagagc ttgggcaaga gcccaatttc agcaaaaaat gaagtaaatc
     7981 ttctcataat aaaacgcatc atatcaagca cgaaaattcc acgaggtcaa ctacagtcag
     8041 aaagctgaac aacaagccaa aacgcccaaa aaaggcggca aaaagcaagc acctgcaagc
     8101 aacgtgccga aatggtcaaa tcctgattat gtcaacgaat tagacccaaa aatcgttgat
     8161 atgctagtag aatttcacaa gtcacaaggc actttggaaa ctcccgaggc gcaagcagaa
     8221 atcgcccaaa aacgtgaaga aatcgagcaa aggagagctg agcttgaggg taaaaaacaa
     8281 gagcttttga accgcttgaa caaatagagt ttcgcaagta ttatgcttac aaattacttg
     8341 agcaattaac taaaatataa actctgccta gatataaagg cagggtttat attttagaaa
     8401 ttcacgtagg ttgttacggt ttttacatac ccagtatagt ttgagtttct atagtattca
     8461 gtgataaact tccattttct ttgagcaaca tggatataag tacttgttat gtagtatgga
     8521 tatgggcttt gtgaatccaa gtaagactga taagcttgta taccaaaata tgctccacca
     8581 attattgcac cccatggacc ccccaataaa gcacctatcc taccaatcat ataactgatt
     8641 ccagcaccag tcatgaagtt agcgaatgtg ttagcttgtt tattcccatg tattgtgttg
     8701 acgtaattcc aaacattagg atcgtatgat ctaaaagata tatttaggtc gatttcattc
     8761 ttttgataag ccatataaaa tgccccattg atatagacgc cgtcagcacg tcgttcaata
     8821 gtgtctacac ttccatctgg attgacaacc tcaagaactt catcgcttaa aatatttact
     8881 tgcgtatctc cgaaccgcac tgatgagcca ttctcaaact gagcctcacc agatacaact
     8941 ttagagtttg ccgataagct atcatcagca aaaacaacaa gcgacgggga aatgctagac
     9001 atacagaaaa cagacataac tagcaaacac atgcatttaa acatcttaga cataacggaa
     9061 actcttttgt atttttgatt tttttcaact tttattatac aataaaacca aataaaaaga
     9121 aagcggtaac aatatgctta atgcgaaaat tttttatata tttttatgtt tgatcgttat
     9181 cgaaactaca ggcttgttgt tgttgaaaag aggtctcgaa atgggttatt tagacacaga
     9241 agctattatc ctcgcagttt tttcatttgc tttttacaac ctatgttcat tcgcttgggt
     9301 ctgctctaca ataaaaaaca ataaaaaata aatagacgta ttttcaaaaa aaaaaaaaaa
     9361 atgcatattt atattagcaa aatgacgatt taaatcgtcg tttttttgta gtacgacggg
     9421 catgtcgtat atctgaggtg taagtcctcg gtgggcacct gctaccggtg aacccaatag
     9481 cgattcccaa gcctgactat cgtgaggtag cggattaaaa cggtctgggg atagaccgtt
     9541 ttaagtctga cgcaggaaat aagaatcgtc agaggaaggg atagcgaaat cgtggctcta
     9601 cgaacaggaa cgtgatagta aggcgtatat agcggataag gaggcttcaa actctaaagt
     9661 ccaaaaaggt agtcgtaacc tatatgtgta aatcacgaga gtaattgaat tcggactaag
     9721 gtttgtgtga aaaagataaa tctttctaga gtctaaagac tctgcgtcag atttcctatt
     9781 ttcactgtaa ccttttaacg tcctcatatc ttgtataaac gaggaaagat gtacgactta
     9841 tcccgtgagg tttcatgagc gctgaaagcg tagtaacaac gaatcatgag aagtcagccg
     9901 agcccatagt agtgaggaaa cttctgtagt ggaagtggag cgaaggggtg aatactcaaa
     9961 cagtctgggg agagactgtt tgaggtctgt cgctagaaag agaaaacgac agatcgaagt
    10021 aatcctactt cacttgtgtc tgtaaaatga gtggtctgat agaactggac tttgacacgt
    10081 aatgactaga tgaaggttca ccaatataag atgtccctca ggcaccaaaa caagaaagga
    10141 atacgcacat gtcaaaactg ctagataaga tattatcacg cgaaaatatg ctggaagcct
    10201 acaatcaagt aaaatccaat aaaggctcag ctgggattga tggaatgact atcgaagaga
    10261 tggataatta tctcagacaa aactggcgct tgactaagga actgataaaa cagagaaaat
    10321 ataagcctca accagttctt aaagttgaga tacctaaacc agacggaggc atccgtcaac
    10381 taggaatttc aacagttatg gatagaatga ttcaacaggc cattgtccaa gtcatgagcc
    10441 ccatttgtga accccatttc tcagatacga gttatggttt cagaccaaat aggtcatgtg
    10501 aaaaagccat catgaagctc ttagaatact taaatgacgg ctatgagtgg atagtggata
    10561 tagacctaga gaaatttttc gatacagttc ctcaagatag attgatgtcc ttagtacata
    10621 acattatcga agacggagat acggaatcct tgattcgtaa gtatcttcat tcaggtgtta
    10681 tcattaatgg tcaacgttat aaaacactag ttggtacacc acagggagga aatttatctc
    10741 ctctcttatc caatatcatg cttaatgaat tggacaagga attagaaaag aggggacttc
    10801 gatttgtgcg ctacgcagat gattgtgtga tacggtcgga agcgaggcag ccgctaagcg
    10861 tgtgatgtat tcagtcagtc gttttattga gaaacggcta ggtttgaaag taaacatgac
    10921 caagactaag attaccagac caagagagtt gaaatatcta ggttttgggt tctggaaatc
    10981 atcagatggt tggaaaagtc gtccacatca agatagtgtt cggagattta agcttaaatt
    11041 gaagaaacta acacagagga aatggagtat agacctaaca agacgtattg agcaactgaa
    11101 tttgtctatt cgaggatgga taaactattt ctcattggga aatatgaaaa gtatagtcgc
    11161 cagcatagat gagcgcttgc gtactcgcct acgagtgatt atctggaagc aatggaagaa
    11221 gaaatcgaga cgattatggg gattgcttaa gttaggagtt cctaaatgga tagcagataa
    11281 ggtatctggc tggggcgacc attatcaatt agtagctcag aagtcggtac ttaaacgtgc
    11341 tatatcaaaa ccagtcctgg aaaaacgtgg actggtttcg tgtttggatt attaccttga
    11401 acgacatgcg ttaaaagtta gttgaaccgc tgtatgccga acggcacgta cggtggtgtg
    11461 agaggggcta gagattatcc cctactcgat taactcccct gaaatttatt ttaattatgc
    11521 aaatttcacg tatttttgat gctgagacga cgatcctggg aacttttcag atattttttt
    11581 gactatctaa atctatcatt agaaaagctt agagcgccaa aggatttgag cgtttttctg
    11641 atttttaaga ctttttccag tctctttttc gattgaagat gtaattattc tactaactaa
    11701 cttcttagta ctagccaaca acgataatca taattcctcc taaaattagg aataataaag
    11761 gcaatagttt ttgttttttc atgtaaaaaa cctcactttt gttttctgct attttatgct
    11821 aaaatattaa aaatcaaatt taattccaaa gtttgtaact aaagggggag cgctacatgt
    11881 ctaattcatt tgtcaagttg ttagtctctc aattatttgc aaatttagca gatattttct
    11941 ttagagtaac aatcattgct aacatataca ttatttcaaa atcagtaatt gccacatcac
    12001 tagttcctat cttaatagga atatcctctt ttgttgcgag tcttttagtt ccgttggtta
    12061 ctaaaaggtt agcgctaaat agggttttat ctttatctca atttggaaag actatattat
    12121 tggcgatact ggtaggaatg tttaccgtaa tgcaatccgt agcgcctttg gtgacctatc
    12181 tatttgttgt tgcaatttcc atactagatg gttttgcagc acccgtttcc tatgctattg
    12241 tgccacgcta tgcgaccgat ttgggtaagg ctaattcagc cttatcaatg actggtgaag
    12301 ctgttcaatt gataggttgg ggattaggtg gactcttgtt tgcaacaatt ggtctgttac
    12361 ctaccacgtg tatcaattta gtcttgtata tcatttctag ctttctgatg ttatttcttc
    12421 ctaacgctga agtggaggtg ttagagtcag aaactaatct tgaaattttg ctcaaaggtt
    12481 ggaagttagt tgctagaaat cctagattaa gactttttgt atcagcaaat ttattggaaa
    12541 ttttttcaaa tacgatttgg gtttcttcca ttatacttgt ttttgtaacg gagttattaa
    12601 ataaaacgga aagttactgg ggatattcta atacagcata ctctattggt attataatta
    12661 gtggcttaat tgcttttagg ctatctgaaa agttccttgc tgctaaatgg gaaagtattc
    12721 tttttcctct tgtagctatg gcaatagtga cactgactat tctatatttt ccaaacgcac
    12781 agatgttttt attattttca gctttagttg gtatgttatc gcaactaaaa gaagttcctg
    12841 aaagtgtatt tcttcaggaa acagtagagg aaaatcattt agttaatgtc tattccgttc
    12901 ttgaagtgat ttctacatta gcattttcag tatttgtttt gctaatgagc tatattactg
    12961 agagttttgg tattagcatc agtttttggc tatcagccat ttgtctgatg atagaagcta
    13021 ttttaattta tatcagacga gattatttta aatgagagag tggttaaaaa gtctttaaaa
    13081 atcagaaaag cgcatagtat caggtgttga aaaaacttga tattgtgtgt tttattatgg
    13141 gaagatttac ttcattgtct cctgaaatgg agttttgaag caggatcact ctatttgaaa
    13201 atatacatag aaaaactgta taatccttaa aataagctga aatctattgg aaacatacgg
    13261 taaacaattg aaaagatact atataaagtg gtacaatggt agaaaaataa gctagtaaga
    13321 atcactctta ttttagcgaa aaattacaga aatgaatggt ttttcttgat gaaacagaga
    13381 aaagaattgt acctctttct tggtcggaca gccttgtatt ttcttatctt tctagggctg
    13441 ctttacttct ttagctatct tggtcagggt caaggaagct ttatctataa tgaattttaa
    13501 cttgaaggag aatccctatt gtgtcaaata aaccaatagc agatatgatt gaaaccattg
    13561 agcattttgc tcagacacag cctagctatc ctgtctataa tgttttgggg caggaacaca
    13621 cttatggcga tttaaaggct gattcggata gtttggctgc agtcattgac caactaggct
    13681 tgcctgagaa gtctcctgtg gttgtttttg gtggccaaga atatgaaatg ttggcaacct
    13741 ttgtagcgct gactaagtca ggtcatgcct acattccaat tgatagccat tcggccttgg
    13801 agcgagtttc agctatttta gaagtagcag agccaagctt gattattgcc atttcagcct
    13861 ttcccttgga gcaggtttct acaccaatga taaatctagc tcaggttcaa gaagcctttg
    13921 cccaagggaa caactatgaa atcacgcatc cagtcaaggg agatgataat tactacatta
    13981 tctttacttc tggtacgact ggtaagccta agggagtgca gatttcacat gataatctcc
    14041 tcagctttac aaactggatg attacggata aggaatttgc gacaccgagt cgtccgcaaa
    14101 tgctggcaca gccaccttat tcttttgact tgtctgtcat gtattgggca ccgaccttgg
    14161 cacttggtgg tacgcttttc actcttcctt cagtcatcac tcaggacttt aagcaactct
    14221 ttgcggctat cttttcattg ccaatcgcta tctggacatc aacaccatcc tttgcagata
    14281 tggccatgtt gtctgaatac ttcaacagtg agaaaatgcc tggaatcacg catttctact
    14341 ttgatggtga agaattgacg gtcaaaacag ctcaaaaact gcgcgagcgt ttcccaaatg
    14401 cccgtatcat caatgcttac ggcccaacag aagcgacagt agctctgtca gcagttgccg
    14461 tgacagacga gatgttagcg actctcaaac gcctaccaat cggctatacc aaggctgatt
    14521 ctccaacctt tatcattgac gaggaaggaa ataaactgcc aaatggcgaa cagggagaaa
    14581 tcattgtttc tgggccagct gtttcaaaag gttatatgaa caatcctgaa aaaacagcag
    14641 aagccttctt tgagtttgaa ggtctgccag cctatcacac aggcgatgtg ggaaccatga
    14701 cagatgaggg cttgcttctt tacggcggac gcatggactt ccagattaag tttaacggtt
    14761 accgcattga gttagaagat gtctctcaaa acctcaacaa gtctcgcttt atcgaatctg
    14821 ctgtcgcagt accgcgctat aacaaggacc ataaggtaca aaatctattg gcttatgtca
    14881 tcttaaaaga cggtgttcgt gagcagtttg agcgagatat cgatattacc aaggccatca
    14941 aggaagacct gacagacatc atgatgtcct acatgatgcc atctaaattc ctttaccgag
    15001 acagtttgcc actaactcca aatggaaaga ttgacatcaa aggattgatt aacgaggtga
    15061 ataagagatg atggagtttt ttcaacagct tcctcattta gagccatatg gcaatcctca
    15121 gtattttgtt tatgtgattg ctgcaacctt gcccatcttt ataggcctct ttttcaagaa
    15181 acgctttgcc tggtatgaag tgttggtaag tctcttcttt attgtcacca tgttggtggg
    15241 tggaaagacc aatcaactag ctgccttggg tatttacctt tgctgggaaa tattgctcct
    15301 gcttttctac aagcattatc gaaaaagcaa ggatggcaag tgggtcttct acttagttag
    15361 ttttctgtcc ctacttccga ttatctttgt caaggtgcaa ccagctatca atggaacgca
    15421 gtctttgctt gggttcttgg gaatttctta cctgaccttt cgttcggttg ggattatcat
    15481 cgagctgaga gatggagtga ttaaggattt taccctctgg gaattcctcc gtttccttct
    15541 cttcatgcca actttctcga gtggtccaat cgatcgcttt aagcgattta atgaaaatta
    15601 tcagaccatt cctgagcgag atgagttgat ggatatgctg gatgaatctg tccgctatat
    15661 catgtggggc tttttgtata agtttatcct agctcatgtt ttaggagaga ccttactacc
    15721 tcctctgaag aatttagcct tgcagtcagg tggcttcttt aatctctatg ccttggcagt
    15781 tatgtatact tttggtctgg agctcttctt tgactttgca ggttattcta tgtttgcttt
    15841 ggccatctca aacttgatgg gaatccgtag ccctatcaac tttaacaagc cctttttatc
    15901 aagggattta aaggagtttt ggaatcgctg gcatatgagt ctgtccttct ggttccgtga
    15961 ctttgtcttt atgcgaatgg tgatggtgtt aaccagaaag aaagtcttta aaaatcgtaa
    16021 tgtaacctca agcatggctt acattgtaaa tatgctgatt atgggatttt ggcatggtgt
    16081 gacctggtac tatatcgcct atggactctt tcatggacta ggcttggtca tcaatgatgc
    16141 ctgggttcgc aagaaaaaaa cgctcaataa ggaacggaaa aaagcaggga aggctgccct
    16201 acctgagaat cgctggattc agttgcttgg catggttgtc actttccatg ttgtcatgtt
    16261 gtcattctta atcttttctg gattcttgaa taatctatgg tttaaaaaat aaaaggaaat
    16321 aaaatatgga tatcaaatca gaagttattg aaattattga tgagttgttt atggaagatg
    16381 tttctgacat gatggatgaa gatctttttg atgcaggtgt cttggatagt atgggaacgg
    16441 ttgagttgat tgtggagatt gagaaccgtt ttgacattcg tgtccctgta acagagtttg
    16501 gtcgtgacga ctggaataca gctaataaaa tcatagctgg tattgtggag ctacaaaatg
    16561 cttaaacgct tatggatgat cttcggaccg gtcttgatcg ctggtttgtt ggtttttctg
    16621 ctcattttct tttatcctac tgagatgcat cataatctag gagctgaaaa gcgttcagca
    16681 gtggctacta ctatcgatag ttttaaggag cgaagtcaaa aagtcagagc actatctgat
    16741 ccaaatgtgc gttttgttcc cttctttggc tctagtgaat ggcttcgttt tgacggtgct
    16801 catcctgcgg tattagctga gaaatacaat cgttcctacc gtccttatct tttaggacag
    16861 gggggagctg catcgcttaa ccaatatttt ggaatgcaac agatgttacc acagctggag
    16921 aataaacaag ttgtgtatgt tatctcacct cagtggttca gtaaaaatgg ctatgatcca
    16981 gcagccttcc agcagtattt taatggagac cagttgacta gttttctgaa acatcaatct
    17041 ggggatcagg ctagtcaata tgcagcgact cgcttactgc aacagttccc aaacgtagct
    17101 atgaaggacc tggttcagaa gttggcaagt aaaggagaat tgtcgacagc agacaatgaa
    17161 atgattgaat tattggctcg ttttaatgaa cgccaagcct ccttttttgg tcagttttcg
    17221 gttagaggct atgttaacta cgataagcat gtagctaagt atttaaaaat cttgccagac
    17281 cagttttctt atcaagcaat agaagatgtt gtcaaagcag atgctgaaaa aaatacttcc
    17341 aataatgaga tgggaatgga aaattatttc tataatgagc agatcaagaa ggatttgaag
    17401 aaattaaagg attctcagaa aagctttacc tatctcaagt cgccagagta taatgacttg
    17461 cagttggttt taacacagtt ttctaaatct aaggtaaacc cgatttttat cattccacct
    17521 gttaataaaa aatggatgga ctatgctggt ctacgagagg atatgtacca acaaacggtg
    17581 cagaagattc gctaccagtt agaaagtcaa ggttttacca atatagcaga tttttctaag
    17641 gacggcgggg agcctttctt tatgaaggac accattcacc ttggttggtt gggttggttg
    17701 gcttttgaca aggcagttga tcctttccta tccaatccca caccagctcc gacttaccat
    17761 ctgaatgagc gctttttcag caaagattgg gcgacttatg atggagatgt caaagaattt
    17821 caatagataa tataatatag aagagttcaa gaatgaaact agttttcacg ttttttcttg
    17881 actctttttt tgcttgtgat ataattaact ggtaaacaaa atgtcaaaga atagtatttt
    17941 tctcttaaaa aagagaagtc taaaaggaaa ggagtcagat atgagacagc tagcaaagga
    18001 tatcaatgct tttttgaatg aggtgatttt gcaggcggaa aatcagcatg aaatcctaat
    18061 aggtcattgc actagcgagg tggccctgac caatactcag gagcatatcc ttatgctctt
    18121 gtcagaggaa tctttaacaa attcagaatt ggcccgtcgt ctcaatgtca gtcaggcggc
    18181 agttaccaag gccattaagt ctttggtcaa ggaagggatg ttggaaacat ctaaagattc
    18241 taaagatgcg cgtgtgattt tttatcagtt gactgacttg gctcgtccaa tcgctgagga
    18301 gcaccaccat caccatgagc atacactttt aacctatgaa caagtggcga ctcagtttac
    18361 tccaaatgaa caaaaagtga ttcagcggtt tttgactgct ttagtaggag aaatcaaata
    18421 atgagatata ttacggtaga ggatttgtcc ttctattatg ataaggagcc tgttcttgaa
    18481 catatcaatt attgtgttga tagtggggaa tttgttacct tgactgggga aaatggagcg
    18541 gctaagacga cgctcatcaa ggctagtctt ggaattctgc aaccacgcat tggaaaggtg
    18601 gctatttcaa agacaaatac gcaaggtaag aaattgagaa tagcctatct tcctcaacaa
    18661 attgccagtt ttaatgctgg ttttccaagt acggtctatg aatttgtcaa gtcgggtcgc
    18721 tatccgagaa aaggctggtt ccgtcgtttg aatgctcatg atgaggagca tatcaaggcc
    18781 agtctggact cagttggcat gtgggaacat cgagacaaac gcttggggtc tctatctggg
    18841 ggacaaaagc agcgagcggt aattgcgcgt atgtttgctt ctgaccctga tgtgtttatc
    18901 ctagacgagc cgacaacggg gatggatgca ggaagtaaaa atgaatttta cgaactcatg
    18961 caccacagcg cccatcatca tggcaaggct gttttgatga ttacccatga ccctgaagaa
    19021 gttaaggatt atgcggatcg caatattcat ctagtccgta accaagactc gccatggcgt
    19081 tgtttcaacg ttcatgagaa tggccaggag gtgggccatg cttagtttat tatcttacga
    19141 ctttatacaa cgcgcctttt tggcggttat tgctatgagt cttttctcac cggtattggg
    19201 aaccttcctc atcttgcgtc gtcagagttt gatgagtgat acccttagcc acgtctcact
    19261 ttcaggtgta gcctttggtc tggttttggg gatttctcca actgtttcta ctattgccat
    19321 tgtcttgatt gcggcggtct ttctggagta tctccgtacg gtttacaaga gctttatgga
    19381 aatcgggaca gctatcctca tgtcaacagg tctggctgtt tctctgattg tcatgagcaa
    19441 gggtaaaagc tcgagttcaa tgagtttgga ccaatatctc tttggttcga tcgtgactat
    19501 cagtgaagaa caggtcattt ccctctttgt cattgcggcg gttgttttga ttttgacctt
    19561 tctctttctt cgtcctatgt atatcttaac ttttgacgaa gatacggcct ttgtggatgg
    19621 cttgccagtt cgtaccatgt ccattctttt taacatggtg acaggggtgg ctattgccct
    19681 tatgattcct gcagcaggag ctcttctggt atcgaccatt atggtcttgc cagctagtat
    19741 tgccctgcgt ctggggaaaa actttaaatc ggttatgctg cttgccagtg cgattggctt
    19801 tttgggaatg gtagcaggac tttacatttc ctactatgca gaaacacctg caagtgcaag
    19861 tattaccatt atttttgtaa ctgtctttat actaatcagt ttagtaagac gttttatcaa
    19921 ataggagacg aacgtgaaaa aaattagctt attactagcc agtctatgtg ccttgttttt
    19981 agtggcttgt tccaatcaaa aacaggcaga tggtaaactc aatatcgtga caacctttta
    20041 ccctgtctat gaatttacca agcaagtcgc aggagatacg gctaatgtag aactcctaat
    20101 cggtgctggg acagaacctc atgaatacga accatctgcc aaggcagttg ccaaaatcca
    20161 agatgcagat acctttgttt atgaaaatga aaacatggaa acatgggtac ctaaattgct
    20221 agataccttg gataagaaaa aagtgaaaac catcaaggcg acaggcgata tgttgctctt
    20281 gccaggtggc gaggaagaag agggagatca tgaccatgga gaagaaggtc atcaccatga
    20341 gtttgacccc catgtttggt tatcaccagt tcgtgccatt aaactagtag agcacatccg
    20401 cgacagcttg tcagcagatt atcctgataa aaaagagacc tttgagaaga atgcagctgc
    20461 ctatatcgaa aaattgcaag ccttggataa ggcttacgca gaaggcttgt ctcaagcaaa
    20521 acaaaagagc tttgtgactc aacacgcagc ctttaactat cttgccttgg actatggact
    20581 caaacaagtc gcaatctcag gactttctcc agatgcagag ccatcagctg ctcgcttggc
    20641 agaattgaca gagtatgtca agaaaaataa aatcgcctat atctattttg aagaaaatgc
    20701 ctcacaagcc cttgctaaca cactttcaaa agaagcaggt gtcaaaactg atgtcctcaa
    20761 tcctttagaa agtctgacag aagaggacac caaggctgga gaaaactaca tttccgtgat
    20821 ggagaaaaac ctcaaggctt tgaaacaaac aacagaccaa gaaggcccag caatcgaacc
    20881 tgaaaaggca gaggatacca agacagtcca aaatggttac ttcgaggatg cagctgtcaa
    20941 ggaccgtacc ttgagtgact atgcaggtaa ctggcaatca gtttatcctt tccttgaaga
    21001 cggcacgttt gaccaagtct ttgactacaa ggctaagtta actggtaaga tgacccaggc
    21061 tgagtacaag gcttactata caaaaggcta tcagacagat gtgactaaga ttaacattac
    21121 tgataatact atggaatttg ttcaaggtgg acaaagcaag aaatacactt acaagtatgt
    21181 cggtaagaaa attttgactt acaagaaagg caatcgtggc gtgcgtttcc tctttgaagc
    21241 cacagatgct gacgctggac aattcaagta tgttcagttt agtgaccaca atgttgcccc
    21301 agttaaggca gaacatttcc atatcttctt tggaggcaca agccaagaag ccctctttga
    21361 agaaatggac aactggccaa cctactaccc agataaccta tctggccaag aaatcgccca
    21421 agaaatgttg gcgcattgat gagaaatcga ctagttcata agagctagtc ggttttttga
    21481 tactagatgg ctaacttcat tatagacctt tcagaactaa gggaacctga aaaaataaat
    21541 aaaactcttg aaatatctgg gcttatatgc tagaatgtag ttagtgtata aggttcatta
    21601 gaacaccaaa gcccctaact agtgccatag ttaagggctt ttttgacgta tcttagcgat
    21661 ttaatgggtg tttataggct agtcagtcgg tctacttctt accatctagc catttgcaga
    21721 cgaaatacaa gataattcca gctataacat ctgctataat agtaagagca agctctggta
    21781 taaggctcat tagtttcacc tcctctcacg aacccatagg aacgtaatcg gtaaccgatg
    21841 acaaaaatag tataccacac taaatttaga tcatcaacct cacttaatgc ttgaactatt
    21901 gtagattata tgctaaaatg tagttaattg ataaggttca ttagaacacc aaagccccta
    21961 actatggccg tagttaaggg cttttttgac gtatcttagc gatttaacgg gtgtttatag
    22021 gctagtcagt cggtctactc cttactatct agccatctgc agacgaaata caagataatt
    22081 ccagctataa catccgctat aatagtaaga gcgagctcta tgataaggct cattagtttc
    22141 acctcctctc acgaacccat aggaacgtaa tcggtaaccg atgacaaaaa tagtatacca
    22201 caataaattt agatcatcaa ggtcacttaa ttcttgaaat atagggtcta ggcgacaaag
    22261 tctttaaaat cagaaaaacg cataatatca ggtgtgcaaa aacttgatac tatgcgtttt
    22321 attgtgggaa ggtttactcc attttctcct gaaattgagt ttttgtccag cctctgtttt
    22381 tggggttgct aagaaaataa tgtcatgtgg tgaatatttg taaatcagtc agcagacaga
    22441 acgaatactc ttcgaaaatc tcttcacatc atgtcagctt cgtctttccg tatatatgtg
    22501 actgacttca tcagttctat ctacaacctc aaaacagtgt ttcgagctga cttcatcagt
    22561 tttcaaatct gtactttgag caagctgaga ctagcttcct atttgatttt cattgaatat
    22621 cagaaaccca ttctccatca aataattcga ctgcgtctaa taatttttga tctggcacgg
    22681 tgtctgaaat aaaggttgtg tatttggaga ggggattaat tttaaaaaat ccagtcttgt
    22741 aaaatttaga actatcaatc agtaagatgg tttcatgggc tttgtcaata atattctttt
    22801 ttgaaatagc ttggctgaga gaagcttcat aaacatattg gtcatcaata cctcttgctg
    22861 aacaaaatgc taaatcgata ttaaaatgat ctaataaaga attttcctta tcatagttga
    22921 ccacggaaca ggattgatgt ttgacctcgc cagatgtgat aaagattttg gagctatctt
    22981 taacagtttc agatagggtt tgtgcagtat gtaaaccatt tgtaaaaata atcaaattat
    23041 caagttcaga aagataggga cagagttcgt agacagtagt actggaatcc agatagatac
    23101 acataccaga ccgaataaag tctttagcga gactagcgat tagtcttttt tgcctagtac
    23161 tttctccttc acgtatttga tgagaaagtt caattgtgtt catagaggac agggtcacgt
    23221 atccgtgctt tcttttgata agaccttgat tttctaagaa aattaaatca cgacgtaagg
    23281 tacttgtgct ggagaaagtg atttctgcca gctcttttac ggcaattctt tttttctttt
    23341 tgataatttc aatcaattca agtacacgtt catcttttat cataagctcc tcctaattta
    23401 tcatttcaac tatattatag cacaaattgg aggaatttga attattttta tgaatattgg
    23461 gttaacattt gaacattatc caagtaagcg ttcacatatt gaaaaaataa aatgtgggga
    23521 ttataataaa cttaatcaag gacgaagaga gaagaaaaat ggaagcggtt ttagcaatag
    23581 atttaggtgc gacttctgga agagcaatcg ttggttacct ttctgaaaat aaactagtaa
    23641 tggaagaaat aaatcgcttt tctaatctac ctattagagt aaaagggcat ttatcttggg
    23701 atgttgactt tctactagct aaaattcttg aaagtatccg cttggctaat actagttaca
    23761 agattttatc tatcggtatt gacacatggg gagttgattt tggcctgatt gataatgaag
    23821 gtaagctgtt atcacaacct gttcattatc gtgatgaaag aacaaaggga gtgttaaagg
    23881 aaatatctga aatgactgaa ttagaaaaac tgtattcaga gacaggaaat cagattatgg
    23941 agataaatac cttgtttcaa ctctttaagg cacgtcaaga atctcctgac tctttctata
    24001 agaccaataa gattctttta atgccagatt tgtttaatta tctcttgaca ggtaagtttg
    24061 ctacagaaaa aagcattgct tcaacaactc aattatttga tcctaggagt caaaattgga
    24121 atcagaatat cttaaaacta tttgaattga attcatcttt acttcctgaa attgtttcag
    24181 agggaaatgt tcttggaagg ataaaaaagg agtatggttt aggcgatatt cctgttgtga
    24241 atgtttgtag tcatgataca gcaagcgcga ttgtctcagt acctaagaca gaaggtagtt
    24301 tatttatttc atcaggtact tggtctttgg ttggagtgga acttacttca ccgattctta
    24361 ctaccgaatc cttcagttat ggatttacaa atgaagtcgg taaagatgga gtgattacat
    24421 ttctgaagaa ttgtacaggg ttgtggatca tagaggaact aagacgttca tttgaacgaa
    24481 gagggaaagc ctattctttt gatgatatta ggacaatggt ggagaaagaa aaagaaaatc
    24541 ttcctctgat tgatactgaa tcaactgaat ttgcaacaga atctgatatg cacaagactt
    24601 tgacagaata tctagcttat catcatgaaa ctagagagtg gacagatgga caactattta
    24661 agattgttta tgaaagccta gctgaaacgt ataggaaagc gatagagtta ctagaagaac
    24721 taactcataa ggtttataag aggatatatg tgattggagg aggtgctaga gccagttatt
    24781 ttaaccaaat gattgctgat agaactggta aagaggttct tacaggttcg actgagggta
    24841 cagctgtggg gaatattgtt gtgcagctca tagctatggg acaattaaaa gggatggaag
    24901 aagctcacca tgttattgag gagtttctac aattagagag ttattactcc caaaagaatt
    24961 aaaaagattg agagtttgta aatttgcctc cctccccctt cttaagtttt gtacaagaag
    25021 gggggataat tggtgaattg aaaaatattt agtgttttga tatgaggagg acaagaatgt
    25081 cagatgtaaa acaagaatta attaagtatg gcaagaagct agtagaaaca gatttgacga
    25141 aaggaacagg tgggaatctc agtgttttcg atcgtgaaaa acaattgatg gcaattaccc
    25201 cgtcgggtat tgatttcttt gaaatcaaag aatccgatat tgtagtgatg gatattaatg
    25261 gaaatgttgt agagggagaa cgcttgccat ctagcgaatg gtatatgcat ttgattcaat
    25321 atcaaactcg tgatgatatc gatgcaatta tccatgctca tacaacttat gcaacagtat
    25381 tagcttgtct cagagaacca cttccggcta gtcattatat gattgcagtg gcagggaaag
    25441 atgttcgggt agctgagtat gcaacatatg gtacgaaaga attggctgtg aatgcagcta
    25501 aagcaatgga aggtcgtaga gcagttttac tagcgaatca tggaatttta gcaggtgcac
    25561 aaaatttatt gaatgcattt aatattgttg aagaagttga atattgtgca aaaatttatt
    25621 gtttagctaa gaattttgga gagccagtag ttcttcctga tgaggagatg gatttaatgg
    25681 cagaaaaatt taaaacatac ggtcagagaa aatagggagg atattaatgt taaaacatat
    25741 accgaaaaat atttctccag atttattgaa gactttaatg gaaatgggac atggagatga
    25801 aatagtatta gctgacgcga attatccttc tgcctcatgt gcaaataagc taattcgttg
    25861 tgatggtgta aatattccag aattattaga ttccattctg tatttaatgc cattagatag
    25921 ttacgtcgat agttcaattc agtttatgaa cgttgtttcg ggtgatgata ttcctaagat
    25981 atggggtacc tatagacaga tgattgaagg tcatggtaca gatcttaaaa cgattactta
    26041 tcttagaaga gaagactttt atgaacgtag taagaaagct tatgctattg ttgctacagg
    26101 agaaacttca ctttatgcta atattatcct taagaaagga gtagttgttg aaagagaaaa
    26161 tgtttaatag aggaatttta gttgccagtc atggtaattt tgctagcgga gctctcatga
    26221 ccgcagaaat gtttgttggt gagacaacaa atgatagagt taggacatta ggtttgatgc
    26281 ctggagagaa tattgtagag tttgaacatt attttaaaaa tcaagtaaat gaactgttag
    26341 actcaaatca agaggttatc gttttgactg acttgattgg aggaagtcct aataatgttg
    26401 ctttgtcacg gtttttaaat ttggattcag ttgatattgt aacagggttt aatatccctc
    26461 tcctagtgga attaatatca aattatgatt caaaaatcaa tttagaagaa attgttcaca
    26521 atgctcaaaa tagtttgttt aatgttaaac aacaacttaa cgtagaggag gaagaagatt
    26581 tatgtctata gagtttgttc gtattgatga ccgtctggta catggtcaag ttgtcactac
    26641 gtggctaaaa aagtatgata ttgagcaagt tatcattgtt aatgatcgca tctcagaaga
    26701 taaaacacga caatctattt taaagatttc tgcaccagta ggtttaaaaa ttgttttctt
    26761 tagtgtaaaa cggtttgtgg aagttttaaa ctctgtgcca ataaaaaaga gaacaatgct
    26821 gatatataca aatccaaaag atgtgtatga ttctattgaa ggaaatttaa aattggagta
    26881 cctcaatgta ggacagatga gtaaaacgga ggaaaatgaa aaggtaacgg gaggtgtagc
    26941 tctaggtgaa gaagacaaat attattttaa gaaaatagtt gataagggaa cgagagttga
    27001 aattcaaatg gttcctaatg ataaagttac aatgttggaa aaatttttat aaaaataatt
    27061 taaggaggta cagtatatgc tattcacaca agcattactg gtgacattag ttgggattat
    27121 tgccactatt gactataatg gaccgttatt tatgattcac cgtccgttag ttacaagtgc
    27181 aatggttggc ttagtcttag gagatttcac ccaaggtgtt cttattggtt cagctcttga
    27241 attaacttgg ctcggtgtaa caggtattgg aggttacact ccaccagata ctatttcagg
    27301 tgcgattatt ggtactgcat ttggtatttt atctggtcaa ggagaaactg ctggtatcgc
    27361 tatagcagtt ccaattgcag ttgctaccca acagttggat gttcttgcaa aaactttaga
    27421 tgtttatttt gtgaaaaaag ctgataatga tgctaaaaac ggagattatt caaagatcgg
    27481 tttttatcat tattcaagtt tggttttaat cacgttattt aaaattgtac caattttcct
    27541 agctattatg cttggagggg aatatgtggc agacttgttt gcgaaggttc caccaatcgt
    27601 tatgcaggga cttaactctg caggtgcttt actaccttca attggttttg gtatgctttt
    27661 aaatatgatg ctcaagaaaa atatgtgggt attcttgttg attggattca tttgttctgt
    27721 gtatggagga atgtcaacca ttgggatctc actagttggt attgcggtag catacttcta
    27781 cgatatgatt ggaagtaaac cacaagaaac aacttcaagt agtgatgttg aggaggatct
    27841 tgatctatga tgaataataa agtaactaaa gttgaactta aaaaagtttt caaacgaagt
    27901 tttatgtatg gttcttcatg gaactatgag agaatgcaga acctaggttt tctatataca
    27961 attcttccag tattgaaaaa actataccca gacaaagatt cagcttctcc tgcaatgaaa
    28021 cgtcaccttg agtttttcaa tactcatcaa acagcggcac catttattct tggagttact
    28081 tccgctatgg aagaacaaga aggaaatgaa ggtgcagctt caattactgg tattaaagtt
    28141 ggcttgatgg ggccactggc tggtctagga gatagtttgt tctggctgac actagttcct
    28201 atctgtttta gtattggtgc gtcttattct aaagacggcg gtgctttagg tatctttatc
    28261 gccttaatat tgtttaatat tattaatatt cctgttaaat atttcggttt gaaatatggg
    28321 tatactaagg gttctagtct tatccaagaa aataatacaa aaggaacatt gaatcgcgtt
    28381 acgagtatgg cgacagcatt agggctagta ctagtgggtg gtttgattcc atcaatggtt
    28441 ggtattaatt ttggattaga atttaagcag ggggaacttg ttatttctgt tcaagaaatg
    28501 attacaaaat taattccagg atttatccct atggctttga ctttattaat gtgtaaatta
    28561 attagaaaag gaaagaatcc ggttgtacta atctttagtg ttatggctat tggagttatc
    28621 ctagttgttt taggaatttt gaagtagtag aaagtgtgga ggtggtattt gggatatcac
    28681 ctccattttg gaagagaggt aaagagtgaa attatggtat aagaaagctg cctcaaattg
    28741 gaatgaagcc ttgccgattg ggaacggtca tttaggtggt atgatttatg gttcagctac
    28801 aaaagaatgt attcaactaa acgatgagac tatttggtat agaggaaagt cagatagaaa
    28861 taatccagac tcactattgc atcttaaaaa aattcgggaa tatcttttag atggagaaat
    28921 tcagaaagcc gaagaattga taaagttaac aatgtttgct accccaagag atcaaagcca
    28981 ctatgaatta cttggggaac tttacattga gcatatagat attcagtctt gtgctctttc
    29041 attgtatgaa agagagctag atttagatac agctatttct aatgttgtgt ttgagcctaa
    29101 tagttgtaat ttacaaataa aaagagaata ttttacgagt tttaataaga atattttatg
    29161 ttgccgtata gtgtcatcag ttcaaaacac attaaattta aacattaatt tgggtagaaa
    29221 taaacggttt aatgatgaag tatctaaact ggattcaagt acaattttaa tgtcggcctc
    29281 tgctggaggt agaaaaggtg ttcagtttaa agtagtatgt cattctaagg ttacggatgg
    29341 tgaagtaagt gtattgggag agacaatagt tattcggaat gctacagagg tatttcttta
    29401 tctcaaatca atgacggatt attggggaaa tatagatatt tcttctcttc agggagaatt
    29461 tagtagtatt gattacttta cagaaaaaga tgaacatgta aaaaaatatc aggagcaatt
    29521 taatagagtt gattttaaac tagactatag taaagattgt cttagcattc caacgaatct
    29581 acttcttgaa aacactaaaa agtatagtaa ctacttgact aacttgttat ttcattatgg
    29641 aagatatctg ttaatatcgt ctagtcaacc gaatggttta cctgccaatc ttcaaggaat
    29701 atggtgtgat gaattaaatc caatttgggg ttctaaatat acgattaata ttaatactca
    29761 aatgaattat tggatggtag gtccatgtga tttaccagaa gtagaatatc cattatttga
    29821 tatgctcgaa agaatgagag aaccgggaag actaaccgct aagaaaatgt atggagctag
    29881 aggttttaca gcacatcata atacggatgg ttttggcgat acggctcccc aatctcatgc
    29941 catgggggct gcaatttggg tattaactat tccatggtta tgtactcata tttgggaaca
    30001 ctatttatat ttccaagatg agcgtattct tacggaacat tttgaaatga taaaagaagc
    30061 atttcttttc tttgaagatt atttatttga ggtggatggc tacttgatga caggtccaag
    30121 tgtctcaccg gaaaataaat atcgcttaaa aaatggtatt gaaggaaatg cttgtctatc
    30181 atctacaatt gataatcaaa ttttaagata tttttgtgat tcatgcattg gaattgcaaa
    30241 acaattagga gacaattcgg attttattag tcgtgtgaag gagttaaaaa agaaattacc
    30301 tagaacaaaa ataggtagta atgggcaaat acaagaatgg ctagaggatt atgaagaagt
    30361 agagcctggt catagacaca tttcacctct atttgggctt tatccttata atgagattga
    30421 tattcataaa actccggaat tagcagaagc agctaaaatc actatcaata gaagattatc
    30481 aaacgctaac tttttatctt cacaggatag ggagcaagcg attaataatt ggttagtaag
    30541 tggtttgcat gctagtacac aaacaggttg gagtgctgca tggctgattc atttttttgc
    30601 gagactatat caaggtgaac ctgcttataa ccagattaat ggtttgttaa ataatgcgac
    30661 tcttggcaat ttatttcttg accatccacc atttcaaatt gatggtaatt taggtttggt
    30721 gagtggaatt tgtgaattat tagtacagag ccatcataat tggttatcac taattccagc
    30781 tttaccttct gcttggtcag aaggagaagt gaaaggtttc agagtaagag gaggatataa
    30841 ggtatcgttt gcttggaaaa atggggatat aacattccta aaattggaag gaggaaacaa
    30901 agatcaaaaa gtaagagtaa gagtatatgg caaaaatact gatgtacaaa atattgaatt
    30961 ggtatttaat tcagaaaaaa ttattgagtt aaatttttag gtataagtca tgaataaaga
    31021 aaaaataaaa agaaaattaa tcacaatact gtttgtatgt attgggatgt tatgttttgg
    31081 attgttagca ggagttaagg ctgataatcg tgttcaaatg agaacgacga ttaataatga
    31141 atcgccattg ttgctttctc cgttgtatgg caatgataat ggtaacggat tatggtgggg
    31201 gaacacattg aagggagcat gggaagctat tcctgaagat gtaaaaccat atgcagcgat
    31261 tgaacttcat cctgcaaaag tctgtaaacc aacaagttgt attccacgag atacgaaaga
    31321 attgagagaa tggtatgtca agatgttgga ggaagctcaa agtctaaaca ttccagtttt
    31381 cttggttatt atgtcggctg gagagcgtaa tacagttcct ccagagtggt tagatgaaca
    31441 attccaaaag tatagtgtgt taaaaggtgt tttaaatatt gagaattatt ggatttacaa
    31501 taaccagtta gctccgcata gtgctaaata tttggaagtt tgtgccaaat atggagcgca
    31561 ttttatctgg catgatcatg aaaaatggtt ctgggaaact attatgaatg atccgacatt
    31621 ctttgaagcg agtcaaaaat atcataaaaa tttggtgttg gcaactaaaa atacgccaat
    31681 aagagatgat gcgggtacag attctatcgt tagtggattt tggttgagtg gcttatgtga
    31741 taactggggc tcatcaacag atacatggaa atggtgggaa aaacattata caaacacatt
    31801 tgaaactgga agagctaggg atatgagatc ctatgcatcg gaaccagaat caatgattgc
    31861 tatggaaatg atgaatgtat atactggggg aggcacagtt tataatttcg aatgtgccgc
    31921 gtatacattt atgacaaatg atgtaccaac tccagcattt actaaaggta ttattccttt
    31981 ctttagacat gctatacaaa atccagctcc aagtaaggaa gaagttgtaa atagaacaaa
    32041 agctgtattt tggaatggag aaggtaggat tagttcatta aacggatttt atcaaggact
    32101 ttattcgaat gatgaaacaa tgcctttata taataatggg agatatcata ttcttcctgt
    32161 aatacatgag aaaattgata aggaaaagat ttcatctata ttccctaatg caaaaatttt
    32221 gactaaaaat agtgaggaat tgtctagtaa agtcaactat ttaaactcgc tttatccaaa
    32281 actttatgaa ggagatgggt atgctcagcg tgtaggtaat tcctggtata tttataatag
    32341 taatgctaat atcaataaaa atcagcaagt aatgttgcct atgtatacta ataatacaaa
    32401 gtcgttatcg ttagatttga cgccacatac ttacgctgtt gttaaagaaa atccaaataa
    32461 tttacatatt ttattgaata attacaggac agataagaca gctatgtggg cattatcagg
    32521 aaattttgat gcatcaaaaa gttggaagaa agaagaatta gagttagcga actggataag
    32581 caaaaattat tccatcaatc ctgtagataa tgactttagg acaacaacac ttacattaaa
    32641 agggcatact ggtcataaac ctcagataaa tataagtggc gataaaaatc attatactta
    32701 tacagaaaat tgggatgaga atacccatgt ttataccatt acggttaatc ataatggaat
    32761 ggtagagatg tctataaata ctgaggggac aggtccagtc tctttcccaa caccagataa
    32821 atttaatgat ggtaatttga atatagcata tgcaaaacca acaacacaaa gttctgtaga
    32881 ttacaatgga gaccctaata gagctgtgga tggtaacaga aatggtaatt ttaactctgg
    32941 ttcggtaaca cacactaggg cagataatcc ctcttggtgg gaagtcgatt tgaaaaaaat
    33001 ggataaagtt gggcttgtta aaatttataa tcgcacagat gctgagactc aacgtctatc
    33061 taattttgat gtgattctat atgacaataa tagaaacgaa gttgctaaga aacatgttaa
    33121 taatttgtcg ggtgaatctg ttagtctaga tttcaaagaa aaaggagcaa ggtatattaa
    33181 agttaaatta ctaacgagtg gagtgccttt gagtttagca gaagtagagg tttttagaga
    33241 atcagatggt aagcaatctg aagaggatat agataaaata acagaagata aagtagtctc
    33301 tacaaataag gtagctactc aaagttcaac caattatgag ggtgtagctg ctttagcagt
    33361 tgatggtaat aaagatggag attacggaca tcattcggtg actcatacta aggcagattc
    33421 taacgcttgg tggcaggtcg atctgggaga agagtttacg gtttctaaag ttgatattta
    33481 taatagaaca gatgccgaac ctcagcgttt atctaatttt gatgttattt ttctatcttc
    33541 atcaggagaa gaagttttta gaagacattt tgataaagta gttgatggtt tgttatcttt
    33601 aaaagtacct tctgtagggg ctaagctagt caaaatagaa ttaaaatcag cagctattcc
    33661 gttaagttta gcggaagttg aagtctatgg ttcaaagaga actccgaaga aactttctaa
    33721 tattgcatta accaaagaaa ctcgacagag ttcaacggat tacaatggtt tttctcgtct
    33781 agcagttgat ggaaataaaa acggagatta tggtcatcat tcagtgactc ataccaaagg
    33841 agattctcct tcatggtggg agatagattt agcacaaacc gaagaattag aaaagttaat
    33901 tatttataat agaacagatg ctgaaattca gagattatca aattttgata ttattatata
    33961 tgattcaaat aatcatgaag tttttaaaca acatattgac agtttagaaa gcaataatct
    34021 atccatagac ttaaaagggc tgaagggaaa aaaggttaga atttctttga gaaacgcagg
    34081 aattccttta agtttggcag aggtagaggt ttatacttat aagtaatttt aaaaattatc
    34141 atcggtagta tgaaagaaac agaaaaataa gaggaaaata gtatgattca acatccacgt
    34201 attgggattc gtccgactat tgatggtcgt cgtcaaggtg tacgcgaatc acttgaagta
    34261 caaacaatga acatggctaa aagtgtggca gatttgattt caagcacatt gaaatatcca
    34321 gatggggaac ctgtggaatg tgtgatttct ccatctacca ttggtcgtgt tccagaggct
    34381 gcagcttccc atgagttgtt taaaaaatca aatgtttgcg caacaattac agttacacca
    34441 tgctggtgtt atggtagtga aactatggat atgtctccag atattcctca tgctatttgg
    34501 ggatttaatg ggacagaacg cccaggagct gtctatcttg cagctgtact agcttcacat
    34561 gctcaaaaag ggattccagc ctttgggatt tatggtagag atgttcagga agctaatgat
    34621 acagctattc cagaagatgt caaagaaaaa cttttacgtt atgcgcgggc agctcttgca
    34681 actggcttga tgagagatac agcttactta tcaatgggga gtgtttcgat ggggattggt
    34741 ggttctattg taaatccgga tttcttccaa gaatacctag gaatgcgaaa tgaatcggta
    34801 gatatgacgg agttcacacg ccgtatggac cgtggtattt acgaccctga agagttcgaa
    34861 cgtgcgctca aatgggtgaa agaaaacgta aaagaaggat tcgaccataa ccgtgaagac
    34921 cttgttttaa gccgtgaaga aaaagataga caatgggaat ttgttattaa gatgttcatg
    34981 attggacgtg acttaatggt tggtaaccca agacttgctg aacttggttt tgaggaagaa
    35041 gcagttggtc accatgcttt agtagctggt ttccaaggtc aacgtcagtg gacagaccat
    35101 ttcccaaatg gggactttat ggaaactttc ctcaatactc agtttgactg gaatggtatt
    35161 cgaaaaccat ttgtatttgc gacagagaat gattcactaa atggtgtgtc tatgctcttt
    35221 aattatctat taacaaatac tccacaaatc tttgctgatg tgcgcactta ttggagtcca
    35281 gaggctgtta aacgtgtaac gggacatact ttagagggtt gtgctgcagc tggcttctta
    35341 catctaatca actctggttc ttgtacattg gatggtacag ggcaagctac tcgagatggc
    35401 aaacctgtta tgaaaccatt ctgggagttg gaagaaagtg aagtgcaggc tatgcttgaa
    35461 aatacagact tcccaccagc aaaccgcgaa tacttccgtg gaggaggatt ctcaactcgt
    35521 ttcttgacga agggggatat gccagtaaca atggtacgtc tcaatcttct aaaaggggtt
    35581 ggtccagtgc tacaaattgc agaaggttat acacttgaac ttcctgaaga tgttcaccat
    35641 actttagata atcgtacaga tccaggatgg ccaactactt ggtttgctcc acgtttgaca
    35701 ggaaaaggtg ctttcaagtc tgtctatgac gtcatgaata attggggagc taatcacgga
    35761 gccataacat atggacacat tggagcagac ttgattacct tggcttctat gttgagaatt
    35821 cctgtcaata tgcataatgt acccgaggaa gatatcttta gacctaaaaa ttggtcctta
    35881 tttggaacag aagatctaga atcagcagac tatcgtgcat gtcagttgtt gggaccgcta
    35941 cataaataaa aattgtgtat ataggaggtg aacttatgtc cctcctatcc ttttaaaaag
    36001 atttgttaaa caattcacaa ataattgaaa acgaatacaa aaactaatat aatgatgtta
    36061 aatagatagc gcggaggcgc aggaggaaaa ttatatggct acattttatg ttccggcagt
    36121 caaccttatt ggtaaaggtg ttgtaaatga agtgggtcct tatatcaagg aacttggcta
    36181 taaaaaggca cttttggtga cagataagta catcgaaggc agtgacattt tacctaaggt
    36241 tttaaaacca ctggatacag aaggaatcga atatgtcatc tttagcgatg tagagccaaa
    36301 ccctacttgt aaaaatgtca cagatggggt agctgctttg caagaacatg gctgtgactt
    36361 tatcatcagt cttggcgggg gttctccaca ggatgcagct agttgtattt ctatcatggc
    36421 tacaaatggt ggaaaaccac aggattatga agggcttcat aagtctgcta aaaaaggctt
    36481 gccagttgtg gctatcaata caacggcagg aacttctgca gaaatcacta ttaactatgt
    36541 gattactgat gaagaacgca aggttaagat ggtaatggtt gacaagaata gccttgctct
    36601 tatctctgtt aatgacccgg aactcatgct ttccaaacct aaaggcctga ctgctgctac
    36661 tggtatggat gctctgactc acgctgttga agctttggta acacctggtg cttatgatgt
    36721 aaccaagaaa ctgtctattg gtgctattga gcttatcaag gaatatcttc ctcgtgctgt
    36781 agaaaatgga catgatattg aagcgcgtga aggtatggtc aatgccatct tccttggtgg
    36841 tatgagcttt aataatgctg gtcttggtta tgttcactca atggctcacc aactcggtgc
    36901 agtatataat ttgccacatg gtgtttgctg tgccatgttg ctaccagtta tagaacgtga
    36961 aaatgctaaa cgtgtaccag aagctttccg caatgttgcc aaagccttgg gacttcatgt
    37021 agaaggtaaa tcagatcaag aatgtgccga ttatgcgatt gttgagattg agaagctttc
    37081 tgagacagta ggtattccta agaaactgac tgaacttggt attgaagaaa aagatttcga
    37141 ctttgaatac ctttctaaga atgccttgat tgatgcctgc gcaccaggaa atccatttat
    37201 gccaacctta gaagaaacga ttgcctttta taaagagtta ttttagcaag agattggacg
    37261 acaataggac aattcacctc taattattga catttcagga aaaatcgcag taaaaacggc
    37321 acagccttct ttaaatgtgc tataatacta gaaaaatact tgtggaggtt ccattatggc
    37381 aatatttttc atgatttttc tgattgtttg tgtgctccta ttggtgatag tcacactgag
    37441 tacagtttat gtggttcgtc agcagtcggt ggcgattatt gaacgctttg ggaaatacca
    37501 aaaggttgct aatagcggta ttcatattcg cttgcctttt gggattgact cgattgcagc
    37561 acggattcag ttgcgcttgt tgcaaagtga tattgtggtt gagactaaga ccaaggacaa
    37621 tgtgttcgtt atgatgaatg tagcgactca gtaccgtgtc aacgagcaga gcgtgacaga
    37681 tgcttactat aaactcatac gtccagaatc tcagattaaa tcttatatcg aagatgctct
    37741 tcgctcttct gttccaaaat taaccttgga tgaattgttt gagaaaaaag atgagattgc
    37801 ccttgaggtt caacaccaag tagcagaaga aatgaccact tacggctaca ttatcgtgaa
    37861 aaccttgatt accaaagtcg aaccggatgc agaagttaag caatccatga atgaaatcaa
    37921 tgcggcgcaa cgtaagcggg tcgcagcaca agaattggcg gaagctgaca agattaaaat
    37981 tgtcactgca gctgaagccg aagcagaaaa agaccgcctt catggtgtgg ggattgccca
    38041 acaacgtaag gcgattgtgg atggattggc agagtctatc accgaactca aggaagccaa
    38101 tgttggcatg acagaagaac aaatcatgtc tatcctcttg accaaccagt atttggatac
    38161 cttgaatacc tttgcctcta aaggaaatca aaccatcttt ttaccaaata ctccaaatgg
    38221 tgtggatgat atccgaacac aaatcttgtc agcccttcgc gctgagaaga aataatagac
    38281 taatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ccttgccgta tagatgttac
    38341 tgacttcgtc agttctatct gcaacctcaa aacagtgttt tgagctgact tcgtcagtct
    38401 tatctactac ctcaaaacgg tgttttgagc aacctgtggc tagtttccta gtttgctctt
    38461 tgattttcat tgagtacaaa gagcttggca acaggctctt tttgtattgc gtttattaag
    38521 aaaaacaaaa aacatcgata tacatttaac taaaaattat tgtatgttat ctcccttaat
    38581 taggaatgat aagggaataa ctagaaagat ttgtgaatac aaactatttc tgatatacaa
    38641 aatatacagt aataatgaat gatgggagat gggatgaaag aatttcaatt tgagagaaag
    38701 cagcgttttt ctttgaggcc atatgcaata ggagcttgtt cggtcttgct aggaacgagt
    38761 ttattttttg atggtatggg tgatcagcct gtacaggata cagaaacgag ttcagcacta
    38821 attttaagtc attatttgga tgagcaggat ttatctgaaa agctgaaatc tgagttgcaa
    38881 tggtttgaat tagaaaacaa gcttttgaac ttatgggagc attaggttac tatgaaggat
    38941 ttgttcctta tgtttcaaat caatacaaaa accaagctga agaagaaggc aaaccgctat
    39001 ctgataaata tattttcgaa aaaatcttag gaaaaacata tgcagccttc aaaaaagatc
    39061 aaattaatga gcgtgtcgag aaattaggta agttaaaacc tattacaata aattacaacg
    39121 gaaaatcaga agtaattgat agtaaagaaa aattacaaga gcttatgaat aaagccgtta
    39181 aagacgaagt ggctcaaata tagtaaaatg aaataagaac aggacaaatc gatttctaaa
    39241 aatgttttag aagtagaggt gtactattct agtttcaata tactataaaa tcaggcaata
    39301 ccacggctaa aaagtttgag tttatcgaaa caccagtgca aacactgaaa aaagcgattt
    39361 ataaagctca tctcaaagat tcagatgact ttaaaccaga aacatccaca taaatctttt
    39421 tgaaagctgt ttgaagcttt gtccttgctt tcttagttca tagatctgaa ctttatcttc
    39481 ataattcaat ttcataataa aacaccccaa aagttagatt tattctgtct aacttttggg
    39541 gtgcagttca ttaatcggtc gatttttttt tgtagaaaca gttgcctgat taagttgcaa
    39601 gtcgatagac ggcttcggca taaatatcca tagcacggta caaatcttct agaacggcac
    39661 attcatttgc ctgatgttct gtctgcttcg ctcctgggaa taaggcgccg aaggctacac
    39721 aatttggcat ggtgcgagca aaagtggcac caccggatga aatagcagga ctgttatcgc
    39781 cagtcttttc ttggtagatt tgcatcagtg tgctaacgag tttactgtct tttgcgacgt
    39841 atagaggcgc tagatagtca aactcttcgt agcggagttg gtagttttgt gcacatcttg
    39901 taagcaactc tactagttct tccttgtcag ctaagacagg agtccgaatg tcaatacgga
    39961 tttcagaacg ttcatgattg atcatgagac ctgcgacatt aaaggatagg tgaccagaag
    40021 gttcatctgc tatatcacca aagatttgtc ttcctgtgcc gtcttgacct gcttgtgttg
    40081 caagaaaact gagagcaggg tgttcttgga gaggagcaag aatggtagct agtcggatga
    40141 cagcattgat accttgacta gcatccttag catgctttgg cactccgaga accgttacgg
    40201 tttgttcagt ggtttggtaa tcataaccag cttctttgag accgttacaa acctgttcat
    40261 agagaagacc ttggtagttg gccttgtctg gtacaacgtt aaaggcgcct cctacttcaa
    40321 gctctagttg atccgatccc gggccatgaa gtttgacctg tagaagccct ttttcagcat
    40381 aggtcagagg aaaagatgag tcaggtgcaa agcccatact ggcctgttct tcgatggtat
    40441 tgtagcgtgc catgcagcgc cagaggtttt cctcatcggt accaaagata aagcgtacgc
    40501 gctttttgaa ctgaatacct tggtccagca agctttttac tgcatagaga gctgcgagcg
    40561 aagggccttt atcatcttgg acaccacgtc cgaataccca gccgtctttg atagttgctt
    40621 caaatggcgg tgtctgccaa tctgcttcat cacctgatgg aacaacatcc aaatgacaga
    40681 gaatggccag aagctctgct ccctgaccga tttctgcata tccgtaataa cctttagggt
    40741 caagataggt agtgaaacct atgtctcgac aaatctctaa agttttttct aggacatctt
    40801 ggattgcttg tccaaaaggt gttccatttt ctccttcatt gagtactgaa ggataggaaa
    40861 tcaaggtttt taatgatata agaaattcat ctttaacttg atttgttata tctattttca
    40921 tggaatcacc tcactcacta ttttatagga atggaaggaa ggttccaagg agaagaaggg
    40981 cgatggtcac tacaataata gcgactacga gtttgcccat gaatttccac caagtaccaa
    41041 tgttgatacg tccaagtgca agagctccca tcacaatacc agatgttggt gcaatcaagt
    41101 tcaagacacc tgaagcagat tgataagcag tgataatcaa gctaggacgg acatttacaa
    41161 attctccaag tggagccatg atacccatag ttgcgctggc aagaccagat gaagatggga
    41221 tcaagaatga cataggtaga tagaagatat aagttacaac gataaagact tgtgaagata
    41281 gaccgctcaa gccttcttta ccccagttga ggattgtatc ggtaatcata ccgtcgttca
    41341 tgataacttg aataccacga gcaatcgcta cgatcaaggc aacactgagc aagtcagcag
    41401 caccattcat gaaggaagag ataatcttat cttctttaag accataaata acaccaatca
    41461 ggatacccat aaaggcaaag agcattgcgc cttctgggaa gtaccaagta cctagtgcag
    41521 aagtagatga accgacaata ttaccaataa ctggaagacc agtcaaccaa gcattaaagt
    41581 catcaaaaat ggtaacgcca aggtctgtcc atggaatgaa gctcaatacc atcaagatga
    41641 atgtcaacac aaataagaag agaactgatt tttgtttgct gctaagtgta gattctacag
    41701 atgaagattc ttctacgtta aagtgtttca aatcttcttt gcgagtacta taaaccagtg
    41761 acttagtcgg atctttttga atcttatccg cataacggta aacaaaccaa gtactaagag
    41821 cagtcaaggt aacccagaag atcagacgaa gtacgatacc gtcccctgta ccaactcccg
    41881 cagtcgctga agcaatacct gtcgcaaatg gattcagagt agatgccaaa cagccgattt
    41941 gagaaccgag caaaataatt gcaacaccag tcaggctatc aaaaccaacg gccatcataa
    42001 ctggcacaag gagtggatag aaggccattg tttcttcacc cataccataa gttgtaccac
    42061 cgagggcaaa caaaggcatt agtaccaaaa ttaacatttt ttcgcggccc ttatacttct
    42121 tcacgataga ggcaatccct acgtcaagag caccagtttt gttgacaatg ccaaggaaac
    42181 caccaaccat aaggatgaag aaggctacat caatcgctgc gctcgtttct ttaatgagcg
    42241 aaccttcctc tggatgagta cctagcatag cccgaattgg tgccatgagg acatcccaaa
    42301 tcccttgtgg attttgaggc tgagtctcgt aaataccttc tataaaggcc cccgcaggga
    42361 taaaccaagt tagtactgcc ataatagcaa tgattatcaa taatacggtg taagatgaag
    42421 gcatcttaaa ccctttttta gctttttcac tcatttgttt ttcctcctga tgtctaacaa
    42481 agtgtaaaaa accaactact ttcttaaata aacatttaag aaaacgcttt ctatttatat
    42541 ttgttttacc atattaaagt ctaaaaaact aatatctttt gaaatattgt acatgttttc
    42601 aagaataatt tctaatttga tataaagata ctagaaatag aatacatctt attagtaaaa
    42661 caacttatcc tttttcaata attgttccac tttcagattc aatcaaggcg cctagatttt
    42721 caagggaagt aataactgct tttccttctg gacgaccatt gacaaaagcg atagctgctt
    42781 ctacttttgg aagcatgcta cctggtgcaa actgatcttg tttgatatat tcttccagct
    42841 gggcaacatt cacatgttcc aatttttcct ggtttggctt gttgtagtta acaaatacat
    42901 aatctacacc tgtcaaaacg atgaagaggt ctgcatcaac caattctgcc aaacgttggg
    42961 aagcgaagtc tttatcaata accgcttcga caccagtcaa atgtccattg ttttctttga
    43021 cgacgggaat accgccacca cctgcagcta cgacgacttg accactattt aaaagagtac
    43081 ggatggtttc aatttctttg atgtcaacag gttttggtga ggcaacgacc ttacgccagc
    43141 cacggccagc atcttccttg aaagtcgctc cgctcttttc ggcttctgct tttgcttctt
    43201 cttctgaata gaaaggaccg attggtttac tcaagttaac aaaagctgga tcatttttat
    43261 ctacgacaac ttgcgttaca acagaggcaa cgtttttttc gatgccttca tccaagagag
    43321 cattttgcaa agcatttttc aaccagaaac cgatgctacc ttctgtcata gcgacaagtg
    43381 agtcgagtgg gaaggcaggg ttcttttcag agtctgatgc caaatgttgg agcaagagat
    43441 tcccaacttg aggtccatta ccgtgagtga taatcagatc atctccattt ttaatcaatt
    43501 ttacaagatg cttagctgtt tcaactaaag cttcttgttg agcctttgct gatgggtcag
    43561 aagaaagaat cgcatttcct cccaaagcta ctacaatttt acgatttgcc ataaattctc
    43621 ctttatcaca ctcaatagaa tgcgtttaga tttcaattta atgatttttc acatatttta
    43681 taagaaataa tagattacca ttacataaaa gaggaccgga ctaaagctat tagtcgcagc
    43741 cctcatagct gttggtagac ggtttattat ctaaaattat actttaggaa tataaaggtt
    43801 accaagtgtc gcagccataa cagctttgat agtgtgcata cggttttctg cttgatcgaa
    43861 gtggcgagcg tacttgctgc ggaagacttc gtctgttact tccatttctt ctacaccaaa
    43921 tttttcagca acgtctttac cataaacagt gtgagtatcg tggaatgctg gcaagcagtg
    43981 taggaagatc aagttttcat tgcctgcttt tttaactaag tccatattga cttggtaagg
    44041 tttaagaaga gctacacgtt ctgcgaattt gtcttcttca cccattgata cccaaacgtc
    44101 tgtgtaaaga acgtctgcat ctttaactgc ttcatcagca tcttcagtga tgagaacatg
    44161 tgcgccactt tctttagcaa atccttctgc caattcaacg atttcttttt ctgggaagag
    44221 ttcttttggt gagaagatgt gaacattgac accaaggata gcacctgtta cgagcaagct
    44281 gttggcaacg ttgttacgtc catcaccaca gtataccaat gtcaagcctt ccaagcgacc
    44341 gaagttttct tgaacagtca agtagtcagc gagcatttga gttgggtgcc attcgtcagt
    44401 tagaccgttc catactggaa cgcctgagaa ttctgccaat tcttcaacca tacgttggct
    44461 gaatccgcgg aattcaatcc cgtcaaacat acgtcccaat actttagcag tatcttcagt
    44521 agattctttt ttacccaact gaatatcatt tgctccgagg tattctgggt gagcaccaag
    44581 gtcgatagcc gcagttgtaa aggctgcacg agtacgagta gatgtttttt caaataggag
    44641 agcgatattc ttgccagcaa ggtagtggtg ttgaatattg cgttttttca aatctttcaa
    44701 gtgagctgaa agaccaataa ggtattctaa ctctgcacgg gtaaagtctt tttctgctaa
    44761 gaagctgcgt ccttggaata ctgaatttgt cattttatta tttcctcttt ctatttttta
    44821 cattttctat tgacgaatgc cgaacagcga ttacacttct tcacgttcaa atggcataga
    44881 catacaacga ggtccaccac ggccccgaac caattcactt ccgcgaatct taatcaagcg
    44941 aagcccgtat tcttccaaaa tcttattggt cacggtattg cggtcataaa caactaccac
    45001 accaggtgcg atggtcaaag tgttagaacc gtcgttccat tgttcacgcg cagctgctac
    45061 gatattgcca ccaccgcaac gaatcaaatg aactttttct acaccaaggt tttgagcaag
    45121 aagttcagct aagtcacctt tctcttcaac gattttaagt ttttcgtttt cgtaagtaac
    45181 tgagtaaacg tgaaggtcgc cttcgatttc tgggtgaata gtgaacttgt catagtctac
    45241 catagtgaag acagtatcca agtgcatgaa tttacggttg ttagcaaatt caaaggccaa
    45301 aactttcttg aagccaacat ttttcttgaa gatgttgacc aaaagttttt cgatagaagc
    45361 tgcgtctgta cgttgagaga tacctactgc aaggacgtct ttagaaagaa ctagctcgtc
    45421 tccaccttcg atacgcgtat cttcttcacg gttgtagacc aaatccactt ttccgccata
    45481 gattgggtgg tatttgaaga tatacttacc gtagagtgtt tcacggttac gagtgtctgc
    45541 aaacatgtgg ttaagcgata cggcgtttcc aattgttgca aatgggtcgc gagtgaaata
    45601 gaggtttggc atcgggtcaa ttgcaaatgg ataatctgat tcaactaagt cagttagatc
    45661 tttagcttcg tcaggaattt ctggcaattc aactttttga atcccagcca ttgttttttc
    45721 aaccaattct tggttgtcct tgatgccgtg aagcaattca cgaatagcaa ccttggtttg
    45781 acgatcacgg atgttggctt cgtctaagta ttcctcgata aattgatcgc ggatttctgg
    45841 agaggtcaat gattcagcag cgagttgttc taggtagaga acctcaattc cttcatcgcg
    45901 aagagcttgg gcaaatgcat catgttcttt ttgagcatct tccaagaaag gaatatcatc
    45961 aaaaagaagc ctttcaagat agtccggcaa caagttttct aactccttgc ctggacggtg
    46021 taacataact tttttcagtt tcccaatttc tgagaagacc tgaattggat gtgaagacat
    46081 gtattttcct ccttaaaaat tttgacttgg caccattttg ggtaccgctt acatgtatgt
    46141 tataacgcaa ttcctaggta atgtcaatgg ctataatttc tcggaaaata atataaatta
    46201 taatatttag cacaatttta tgttattata cataacatag gatagaatac atagatacaa
    46261 atgcataaac ttctataaaa aggatataaa atttttttaa aaaatttttc aaaaaatata
    46321 caaatgacca aaaagtgtcc aattatcatc tggttatcac ttggatctgt ataaagagaa
    46381 atgtttgtgt gaaaggataa aaagatgcaa cattcttttg aagatagatt ttggagaagc
    46441 atttcttgtt caattgtaca aattatagaa tcttttctga gtatttagga agagataatt
    46501 atcttattga ccctcttttt attttttgtt atagtcgacg aggtgatagt ttagaataat
    46561 cacttattca caatctgtgg aaaagtctgg agagtgaatg gtcttcacac aatgacctga
    46621 aagaagcctg agaataatta tggagagtag cattctgaga ggtgttagca gaaccatatg
    46681 acagagctgt ttgaagaggg aatattgagg agaaaaatcc tgagcctacc agttggagtt
    46741 ggaaagagct ggctgttaga tcatggttta ttatccacaa cctgtggata accttgtgaa
    46801 caagagaagt tgctaaagaa ggagatatat aacgatgaag aaaatcaaac cgcatggacc
    46861 gttaccaagt cagactcagc tagcttatct gggagatgaa ctagcagctt ttatccactt
    46921 cggttctaat accttttatg accaagaatg ggggactgga caggaggatc ctgagcgctt
    46981 taacccgagt cagttggatg cgcgtgagtg ggttcgtgtg ctcaaggaaa cgggcttcaa
    47041 aaagttgatt ttggtggtca agcaccacga tggctttgtc ctttatccga cagctcacac
    47101 agattattcg gttaaggtca gtccttggag gagaggaaag ggcgacttgc tccttgaagt
    47161 atcccaagct gccacagagt ttgatatgga tatgggggtc tacctgtcac cgtgggatgc
    47221 ccatagtccc ctctatcatg tggaccgaga agcggactac aatgcctatt atctggctca
    47281 gttgaaggaa atcttatcaa atcctaacta tgggaatgct ggtaagttcg ctgaggtttg
    47341 gatggatggt gccagaggag agggcgcgca aaaggttaat tatgaatttg aaaaatggtt
    47401 tgaaaccatt cgtgacctgc agggcgcttg cttgattttt tcaacagaag gcaccagtat
    47461 ccgctggatt ggcaatgaac gagggtatgc aggtgatcca ctgtggcaaa aggtgaatcc
    47521 tgataaacta ggaacagaag cagagctgaa ctatcttcag cacggggatc cctcgggcac
    47581 gattttttca atcggagagg cagatgtttc catccgtcca ggctggttct accatgagga
    47641 tcaggatcct aagtctctcg aggagttggt cgaaatctac tttcactcag tagggcgagg
    47701 aactccactc ttgcttaata ttccgccgaa tcaagctggg ctctttgatg caaaggatat
    47761 tgaacgactt tatgaatttg cgacctatcg caatgagctc tataaagaag atttggctct
    47821 gggagctgag gtatctggtc cagctctttc cgcagacttt gcttgtcgcc atttgacaga
    47881 cggccttgag accagctctt gggcaagcga tgcagacttg cccatccagt tagaactcga
    47941 cttaggttct cctaaaactt ttgatgtaat tgagttaaga gaagatttga agctagggca
    48001 acgaatcgct gcttttcatg tgcaagtaga ggtggatggt gtctggcagg agtttggttc
    48061 gggtcatact gttggttaca aacgtctctt acgaggagca gttgttgaag cacagaagat
    48121 acgtgtagtc attacagaat cacaggcttt gcctttgttg accaagattt cactctataa
    48181 aactccgagg ttatcacaaa cagtagctgt tcaggggcta gcatttgcag aaaaaagcct
    48241 agctgtggca aagggagaga ctcttcattt taggattgaa cgtagtgaaa gtagctcctc
    48301 tttagaggct aagatttcga ttcaaccggg gacaggtgtc catggtgtcg cctatcagga
    48361 tgagattcaa gtccttcaat tccaagcagg ggaaagcaaa aaagatttgc atctaccaac
    48421 cctgtatttc gcaggagata aaaccttgga tttctatctg aacctaacgg tggatggtca
    48481 gcttgtggat caacttcaag tccaagtttc ataaaagaag aacctttgcg cgatgcaaag
    48541 gttcttttgg ttattagtga cttggtaacc agctgagggt gaaagttagt tgttcagctt
    48601 ttaagaggtc ttggtgttga atagttgata cgagtgtttt gtccagtcgg cattctttga
    48661 caaagttaaa atggttgtgg ttttgtttag tatggatatc cagccattta tcttctttag
    48721 cgaggtagac tcgtagatgg tcaaagagag ggattccgag gtcatagctt ggttttcctg
    48781 gacaggttgg ataaaatccg agagctgacc agatgtacca agcagagaga ctaccattgt
    48841 cttcatctcc aggataggct tcccaacttg ggtgaaaagc tttctgacgg agcgtcttga
    48901 taagaagggc agtgtagtca gggtaatcgc tgtagcggaa gagataagga atgtggaaac
    48961 taggctggtt ggaaatggct atttgtccaa aaggagcagt agccatctcg ctcatttcgt
    49021 gaatttcgta accatagcct gttgtttcaa agaggggagc atcttgacag gctttcaaaa
    49081 gatagttgct aaaggtttct tttccaccca tcagttggat taagccaggg atgtcgtgga
    49141 gaacgcctaa agtagcttga atggcagagc attcagcgta gtctcgcccc caactataag
    49201 gagagaagtc agggtgaaag tttccttgat tgtctcgtgc tcgcatgtaa cctgtctcag
    49261 cgtcaaatag ctggcggtaa ttttgtgaag cagccttgta ggtttcagcg atttctatgt
    49321 tctctagttt tttggcacag ctggcgatac aaaagtcact ataggcatag tctagagtat
    49381 ggctaacact ttcgtggtgg tcggtagaga ggtaacctag ttcttggtat tgggctagtc
    49441 cgtggcggcc attgattccg agagggtcgg ctttgctggc tgtttcgagc atggcttgga
    49501 agagttctcc ttctaggtca ggggccatgt ccttgcaggc gctatctgcg ataataccgt
    49561 ctaaaagtgt acctggcatc ataccccgtt catctggagc cagccatttt ggaaggaaac
    49621 cagtatcgcg gtagctattg aggaaacctt ctaaaaagcg ttgatagtgc tccggtatga
    49681 taagggcaaa gagggggaag gtggtgcgga aggtatccca gaaaccattg ttgctaaaga
    49741 ggacaccagg cttgacagta ccagtagcca gatccatgtg gatggcttgc cctgactcat
    49801 caacctcata aaaagtctgt gggaagagga agagtctgta gaggcagtgg tcaaagaagg
    49861 ttcggtcagc ctctcctgtc tctataatgt caaaacgatg gaggagattt tcccaatccg
    49921 cttgggcact tgctttacag ctatcaaaat cttcttgagg tagattaagc agtgcttgag
    49981 aaggagagat gaaagaagtg gctagttgca tctcggtttg actacttgct aagtcaattc
    50041 gccagtcccc agcttcttgg ctgatagcaa gaatatccgt gttcatttgc agggcagtga
    50101 acatcgttag cgaatttttg ttggtttcag ttttaccttc ttgtcgcagg gcaagagttc
    50161 gcttatctac ttgctctact gtcagttcat ctgttgcgtg aagatagagg gagagggctt
    50221 tgccttgctt ttgcttcaaa cgaatagaag caccgtagca agtcggtgtg agctgggttt
    50281 caatctgata acgcagagaa aagagcttca aatagtgagg ctggaagcaa gctttatcta
    50341 tatcataaga agactggcgg tgaaagaggc tgtctccccc cagttgactg gtgacaggtg
    50401 tcagaaggag ccaagagtag tccccaatcc aaggactggg ctggtgagtt aatcgaatcc
    50461 cctgaaagat aggcagatgc ggatcaaaaa accaagatcc atcctggtca ctggtctggg
    50521 gcacaaagta attcatccca aaaggcacgc ctgtgtatgg cagggtattt ccccaagaga
    50581 aggcatgctt gctagcagta ccaaagcggg tatcgatggt ttcaagtagt ggtttcatag
    50641 tctttccttt agctgttttt ctacattata tcagaaaaag agggacttta gaaaaggagt
    50701 ttcaaaaata actattttgt agaaaaatga ctatcatttg tgtatgtatt ttctgtctca
    50761 aaagctatat actgaacatg aaacttgttt gaaagaggga attgcacgat gatttattcg
    50821 aaagaaattg ttagagaatg gctagatgaa gtagcagagc gggctaagga ccatccagag
    50881 tgggtggatg ttttcgagcg ttgctacacc gataccttgg acaatacggt tgaaatctta
    50941 gaagatggtt caacttttgt cttgactggg gatattcctg ctatgtggct tcgggattcg
    51001 acagcccagc tcagacccta cctgcatgta gctaaaagag atgccctcct gcgtcagacc
    51061 attgcaggtt tggtcaaacg tcagatgacc ttggtactca aggatcctta tgccaattcc
    51121 ttcaacatag aggaaaactg gaaggggcac cacgagaccg accacaccga ccttaatggc
    51181 tggatttggg aacgcaagta tgaggtggac tcgctttgct atcctttgca gttggcttat
    51241 ctcctctgga aagaaactgg cgagactagt cagtttgatg agacttttgt cgcagcgact
    51301 aaggaaattc tccatctatg gacagttgaa caagaccaca agaactctcc ttatcgtttt
    51361 gtccgagata cggaccgtaa ggaagacacc ttggtaaatg atggctttgg acctgacttt
    51421 gcagtgacag gtatgacttg gtcagccttt cgtccgagtg atgactgttg ccagtatagt
    51481 tacttgattc cgtcaaatat gtttgctgta gtagtcttgg gttatgtgca agaaatcttc
    51541 gcagcattaa acctagctga tagccagagt gttattgctg atgccaagcg tcttcaggat
    51601 gaaatccaag aaggaatcga aaactacgct tacaccacca acagtaaggg tgaaaagatt
    51661 tatgcctttg aagtggatgg cctaggaaat gccagcatta tggatgatcc aaacgtacca
    51721 agtctactag ctgcgcccta tctgggctac tgttcggtcg atgatgaagt gtatcaagct
    51781 actcgccgta ccattctgag ctctgaaaat ccatatttct accaaggaga atacgctagc
    51841 ggtcttggaa gttctcatac cttctatcgc tatatctggc caatcgccct ttctatccaa
    51901 ggcttgacaa caagagataa ggcagagaaa aacttcttgc tggatcagct ggttgcctgc
    51961 gatggcggta caggtcttat gcatgaaagc ttccacgtgg atgacccaac tctctactct
    52021 cgtgaatggt tctcctgggc taacatgatg ttctgtgagt tggtcttgga ttacttggat
    52081 attcgctaag gggctcgctt tagctcaacc gattcttatc agaatcacaa gtttacattt
    52141 aaaacgttaa aatttaaatt tagaatgagg ttttacttca tggaaaatgt tgttgtacat
    52201 attatctcac atagtcactg ggaccgtgag tggtacttgc cttttgaaag tcatcgtatg
    52261 cagttggtgg aattgtttga caatctcttt gatctctttg aaaatgaccc tgagttcaag
    52321 agtttccact tggatggaca aactattgtc cttgacgact acttacaaat tcgccctgaa
    52381 aatcgcgaca aggtccaacg ctacattgac gagggcaagc ttaaaattgg tcccttttac
    52441 atcttgcagg atgattattt gatttcaagt gaagccaatg tccgcaatac cttgattggt
    52501 caacaagaag ctgccaaatg gggtaaatca acccagattg gctactttcc agataccttt
    52561 ggaaatatgg gacaagcacc tcaaattctt caaaaatcag gcattcatgt ggcggccttt
    52621 ggtcgtggtg tgaagccgat tggatttgac aaccaagtcc ttgaagatga gcagtttaca
    52681 tcccagtttt cagaaatgta ctggcagggt gtggatggta gtcgtgtttt aggtattctc
    52741 tttgccaact ggtacagtaa tgggaatgaa atcccagttg acaaagatga ggccttgacc
    52801 ttctggaaac aaaaattgtc agatgtgcgt gcctacgctt cgaccaacca atggttgatg
    52861 atgaacggct gtgaccacca gcctgtacag aaaaatctga gcgaagccat tcgtgtggca
    52921 aatgaactct tcccggatgt aatctttgtt catagttctt ttgatgaata tgttcaagct
    52981 gtagaaggtg cgcttcctga acacttatca actgttacag gcgagttgac cagtcaggaa
    53041 acagatggct ggtacacact tgccaacact tcttcatccc gcatttacct gaaacaagcc
    53101 ttccaagaaa atagcaacct cctagagcaa gtggtagaac ccttgactat tatcactggt
    53161 ggacacaacc acaaggacca gttgacctat gcttggaaaa cacttttgca gaacgcgcca
    53221 catgatagta tctgtggctg tagcgtggac gaagttcacc gcgagatgga aacgcgtttt
    53281 gccaaggtca accaagtagg aaactttgtt aaaagtaact tgctcaacga gtggaagggt
    53341 aaaattgcta cggataaggc tcaaagtgac tatctcttta ctgtcattaa cacaggcttg
    53401 catgataagg tcgatactgt cagcacagtg attgatgtgg cgacttgtga tttcaaggaa
    53461 ttgcacccaa cagaaggcta caaaaagatg gctgctctta tcttgccaag ttaccgtgtg
    53521 gaggacttgg atggtcgtcc tgtagaggct acaatcgaag acctcggagc taattttgag
    53581 tacgatttac caaaagataa gttccgccaa gctcgtattg ctcgacaagt gcgcgtgacc
    53641 attccagttc acctagcgcc gctttcttgg acaaccttcc aattgctgga aggaaaacaa
    53701 gaacaccgtg agggtattta ccaaaacgga gtgattgata caccattcgt aacggtgagt
    53761 gtggatgaca acatcacagt ctatgacaag acaactcacg aagcctatga agactttatc
    53821 cgctttgaag accggggtga catcggaaac gagtatatct atttccaacc aaaaggaaca
    53881 gagccaatct ttgcagagct taagggccac gaggtcttgg aaaacacaga tcgctatgct
    53941 aaaatcttgc tcaaacatga attgaccgtg cctgtcagtg cggatgaaaa gctagaagaa
    54001 gagcaacaag gtatcatcga gtttatgaag cgtgaggctg gacggtcaga agaattgaca
    54061 aacattcctc tggaaactga gttgattgtc tttgttgaca atccacaaat ccgcttcaag
    54121 actcgcttta ctaacactgc caaggatcac cgtatccgtc tcttggtcaa gactcataac
    54181 acgcgtccaa gcaatgattc tgaaagtatc tatgaggtgg tgacacgacc aaacaaacca
    54241 gctgcttcat gggaaaatcc tgaaaatcct caacaccaac aagcttttgt cagtctgtat
    54301 gacgatgaaa aaggggtgac tgtatccaac aagggattga atgaatacga aatccttggg
    54361 gataacacca ttgccgtgac cattttgcgt gcatcaggtg agctaggtga ctggggctac
    54421 ttcccaacgc cagaagcaca atgcttgcgt gagtttgaag tcgaatttgc gattgaatgc
    54481 caccaagccc aagaacgctt ctcagcctat cgtcgtgcca aagccttgca gacaccgttt
    54541 accagccttc agcttgctag acaggaagga agcgtggttg cgactggtag cctcttgagc
    54601 cattctgttc tcagcatacc gcaagtttgt ccaacagcct ttaaagtggc ggaaaatgaa
    54661 gaaggctatg tcctccgtta ctataatatg agtcaagaaa atgtgcgcat atcagaacat
    54721 caacaaacca ttcttgactt acttgagcga ccatatccag ttcattcagg actattggct
    54781 ccacaagaga ttcgtacaga attcatcaaa aaagaagaaa tttaatttca aaaagtaaac
    54841 atcaaaagaa aggaggggcg aaaaagtaag aactaactgc tgattcgccc ctttttatgg
    54901 taaaaacaat gaccattgca acgattgata tcggagggac tgggattaag tttgccagtc
    54961 tgactcctga tgggaaaata ctggataaga caagtatttc aacgcctgaa aacttggagg
    55021 atttactagc gtggctagat caacgcttgt cagaacagga ttacagtggg attgctatga
    55081 gtgttccagg tgcagtcaat caagagacag gtgtgattga tggcttcagt gcggtgccct
    55141 acatccatgg cttttcttgg tatgaggcgc ttagctctta tcagctacct gtccatttag
    55201 aaaatgatgc caactgcgtt ggactcagtg aactactagc tcatccagag cttgaaaatg
    55261 cagcctgtgt cgtgattggg acagggattg gcggagccat gattatcaat ggtagacttc
    55321 atcgaggtcg ccacggtctg ggtggagaat ttggctacat gacaaccctt gcccctgctg
    55381 aaaaacttaa taactggtcg caactagcat caactgggaa tatggtacga tacgtgattg
    55441 aaaaatctgg tcatactgat tgggacggtc gcaagattta ccaagaggcc gcagctggta
    55501 atgctctttg tcaagaagcc attgagcgca tgaaccgcaa tttgacgcaa ggcttgctca
    55561 atatccagta tctcatcgat ccagatgtca tcagtctggg tggctctatc agtcaaaatc
    55621 cagattttat ccaaggtgtt aagaaggctg ttgaagactt tgtcgatgcc tacgaagaat
    55681 acacggtcgc accagttatc caggcctgca cctatcacgc agatgccaat ctctacggtg
    55741 ctcttgtcaa ctggctacag gaggaaaagc agtggtaaga tttataggac ttagtcccaa
    55801 acaaacgcaa gctattgagg ttttaaaagg tcacatttct ctaccagatg tggaagtggc
    55861 tgtcactcag tctgaccaag catctatctc tatccagggt gaggaaggtc actatcaatt
    55921 gacctatcgc aaacctcacc aactttatcg tgccttgtcc ttgttggtaa cagttctagc
    55981 agaagctgat aaagtagaga ttgaggaaca agcagcttac gaagatttgg cttacatggt
    56041 tgactgttct cgaaatgcgg tgctgaatgt ggcttctgcc aagcagatga ttgaggtctt
    56101 ggctctcatg ggctactcaa cctttgagct ttacatggaa gacacttacc agattgaagg
    56161 acagccttac tttggctatt tccgtggagc ttattcagca gaggagttgc aggaaatcga
    56221 agcctatgcc caacagtttg acatgacctt tgtaccatgc atccagacct tggcccactt
    56281 gtcggccttt gtcaaatggg gtgtcaagga agtgcaggag ctccgtgatg tagaggacat
    56341 tcttctcatt ggcgaagaaa aggtttatga cctgattgat ggcatgtttg ccacgttgtc
    56401 taaactgaag actcgcaagg tcaatatcgg gatggacgaa gcccacttgg ttggtttggg
    56461 acgctacctg attttgaacg gtgttgtgga tcgtagtctc ctcatgtgcc aacacttgga
    56521 gcgcgtgctg gatattgctg acaaatatgg tttccactgc cagatgtgga gtgatatgtt
    56581 cttcaaactc atgtcagcgg atggccagta cgaccgtgat gtggaaattc cagaggaaac
    56641 tcgtgtctac ctagaccgtc tcaaagaccg tgtgactctg gtttactggg attattatca
    56701 ggatagcgag gaaaaataca accgtaattt ccgcaatcat cacaagatta gccatgacct
    56761 tgcatttgca gggggagctt ggaagtggat tggctttaca cctcacaacc attttagccg
    56821 tctagtggct atcgaggcta ataaagcctg ccgtgccaat cagattaaag aagtcatcgt
    56881 aacgggttgg ggagacaatg ggggtgaaac tgcccagttc tctatcctac caagcttgca
    56941 aatctgggca gaactcagct atcgccatga cctagatagt ttgtctgcgc acttcaagac
    57001 caatactggt ctaacggttg aggattttat gcagattgac cttgccaacc tcttaccaga
    57061 cctaccaggc aatctcagtg gcatcaatcc caaccgatat gtcttttatc aggatgttct
    57121 ctgtccgata cttgaccgac acatgacacc tgaacaggac aaaccgcact tcgctcaggc
    57181 tgctgagacg cttgctaaca ttaaagaaaa agctggaaac tatgcttatc tctttgaaac
    57241 tcaggcccag ttgaatgcta ttttaagtag caaagtagat gtgggacgac gcattcgtca
    57301 ggcctaccaa gcggatgata aagaaagttt acaacaaatc gccagacaag aattaccaga
    57361 acttagaagc caaattgaag acttccatgc cctctttagt caccaatggc tgaaagaaaa
    57421 caaggtcttt ggtttggata cagttgacat ccgtatgggc ggactcttgc aacgcatcaa
    57481 acgagcagaa agccgtatcg aggtttatct ggctggccag cttgaccgca tcgacgagct
    57541 ggaagttgaa atcctaccat ttactgactt ctacgcagac aaggatttcg cagcaactac
    57601 agctaaccag tggcatacca ttgcgacagc ttcgacgatt tatacgactt aatactcttc
    57661 gaaaatctct tcaaaccacg tcagcttcca tctacaacct caaaacagtg ttttgagcag
    57721 cctgcagcta gcttcctagt ttgctctttg attttcattg agtataaaaa caagaacacc
    57781 ttgcttggcg cagggtgttt cgcgtgaaac agaagaatta tctggtttca aatgctacag
    57841 ttaaaattag taaaacaaga aatagaagct gaaaagccag catctgtaga ggcttggatc
    57901 atttccgtca aatttaaaaa aggttgctac cgacatatat agattccaaa aacaaaaacg
    57961 ttagcggaac tagcagatgt gattttatgg agttttgatt ttgcaaatga tcatgctcac
    58021 gcatttttca tggataatat tgagtggagt catgcagatt cttactttct tagctttgtt
    58081 agtgacgatg ttgaagaacg ttacacagaa aatgtctatc tggatagcct aagtgtcaaa
    58141 caaaaattta agtttatttt cgacttcggt gatgaatggc gttttgaatg ccaagtgctg
    58201 agagaaatcg agacagagga cgaagaagct tatctcgtac gttcggttgg aacgtcgcca
    58261 gaacaatatc cagattatga tggttttgac tatgaagaat ggtaaaattg aaatcagtct
    58321 gtgtaggctt agtatttcaa tagacttcct gcaaaactag aatcctagtt catgattgat
    58381 aataccagca atcaaattca ttcgtaatcc gaagcgttta cgatgatttc gataggttgt
    58441 tgaaaacatt ttaaacgttt ttactttggc aaagatgttc tcaaccttgc ttctctcctt
    58501 ggatagcgca tggttatagg ctttatcttc agctgttagt ggcttgagtt tgctggattt
    58561 acgtgaagtt tgtgcttgag gacatatctt catgagccct tgataaccac tgtcagccaa
    58621 gattttacca acttgtctga tatttctgca actcattttg aacaacttca tatcatgaca
    58681 atagttcaca gtgatatcca aagaaacaat tctcccttga cttgtgacaa tcgcttgagc
    58741 cttcatagcg tgaaatttct ttttaccaga atgattcgct aattgttttt ttagggcgat
    58801 tgatttgtac ttccgtcgca tcaatcatta ccgtgtcctc agagctgaga ggagttcttg
    58861 aaatcgtaac accactttga acaagagtta cttcaaccca ttggctccga cggattaagt
    58921 tgctttcgtg gataccaaaa tcagccgcaa tttcttcata agtgcggtat tctcacacat
    58981 attgaagagt ggccataaga aggtcttcta ggcttaattt aggttttcgt ccaccttttg
    59041 cgtgtttaag ttgataagct gtttttaata cagctaacat ctctttaaaa gtcgtgcgct
    59101 gaacaccaac aagacgctta aatcgtgtat cagttaattg tttacttgct tcataatttc
    59161 gcagggagtc tattgactct ttggtaggtg tcaatgtttt tttcatctat cccgagaatt
    59221 attttcccgc catttgtatt tgcaaatgct gagtaggttt cccagaaaga ctctggaaga
    59281 ttgtttttag cttttttgta ttctaaatca accccttcaa attttaagtc catatttttc
    59341 ctttacatct gttttttgtg gttctggtat ttgttcaagt tgagtgataa tatagcgaat
    59401 tgaatttcga gagtttttac tcagttaatt tcttttttaa cccactttaa tttctttttt
    59461 aacacgggtt aaaaaagaaa ttaaagtggg ttaattttcc ttgacttaaa atttaaaaat
    59521 gatatactgt gtttatggag agatgacaat ttataaaatg tactactcta ttctactaga
    59581 taatgattga ataaaacttt ttataacaac ggctagcaaa gttataattt tatatctatt
    59641 agaaaataaa tatgtaagga aatttaaatg aaaaaaacta caatattatc attaactaca
    59701 gctgcggtta ttttagcagc atatgtccct aatgaaccaa tcctagcaga tactcctagt
    59761 tcggaagtaa tcaaagagac taaagttgga agtattattc aacaaaataa tatcaaatat
    59821 aaggttctaa ctgtagaagg taacatagga actgttcaag tgggtaatgg agttactcct
    59881 gtagagtttg aagctggtca agatggaaaa ccattcacga ttcctacaaa aatcacagta
    59941 ggtgataaag tatttaccgt tactgaagta gctagtcaag cttttagtta ttatccagat
    60001 gaaacaggta gaattgtcta ctatcctagc tctattacta tcccatcaag cataaaaaaa
    60061 atacaaaaaa aaggcttcca tggaagtaaa gctaaaacta ttatttttga caaaggcagt
    60121 cagctggaga aaattgaaga tagagctttt gatttttctg aattagaaga gattgaattg
    60181 cctgcatctc tagaatatat tggaacaagt gcattttctt ttagtcaaaa attgaaaaag
    60241 ctaacctttt cctcaagttc aaaattagaa ttaatatcac atgaggcttt tgctaattta
    60301 tcaaatttag agaaactaac attaccaaaa tcggttaaaa cattaggaag taatctattt
    60361 agactcacta ctagcttaaa acatgttgat gttgaagaag gaaatgaatc gtttgcctca
    60421 gttgatggtg ttttgttttc aaaagataaa actcaattaa tttattatcc aagtcaaaaa
    60481 aatgacgaaa gttataaaac gcctaaagag acaaaagaac ttgcatcata ttcgtttaat
    60541 aaaaattctt acttgaaaaa actcgaattg aatgaaggtt tagaaaaaat cggtactttt
    60601 gcatttgcgg atgcgattaa acttgaagaa attagcttac caaatagttt agaaactatt
    60661 gaacgtttag ccttttacgg taatttagaa ttaaaagaac ttatattacc agataatgtt
    60721 aaaaattttg gtaaacacgt tatgaacggt ttaccaaaat taaaaagttt aacaattggt
    60781 aataatatca actcattgcc gtccttcttc ctaagtggcg tcttagattc attaaaggaa
    60841 attcatatta agaataaaag tacagagttt tctgtgaaaa aagatacatt tgcaattcct
    60901 gaaactgtta agttctatgt aacatcagaa catataaaag atgttcttaa atcaaattta
    60961 tctactagta atgatatcat tgttgaaaaa gtagataata taaaacaaga aactgatgta
    61021 gctaaaccta aaaagaattc taatcgggga gtag
//
LOCUS       DAYYYC010000004        57734 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.004, whole genome shotgun sequence.
ACCESSION   DAYYYC010000004 DAYYYC010000000
VERSION     DAYYYC010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57734
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.004"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            380..3277
                     /gene="nanA"
                     /locus_tag="ACHBV5_000239"
     CDS             380..3277
                     /gene="nanA"
                     /locus_tag="ACHBV5_000239"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HFM9966111.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4292..4744
                     /locus_tag="ACHBV5_000240"
     CDS             4292..4744
                     /locus_tag="ACHBV5_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HFM9966112.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            4763..6100
                     /locus_tag="ACHBV5_000241"
     CDS             4763..6100
                     /locus_tag="ACHBV5_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM9966113.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6179..7063
                     /locus_tag="ACHBV5_000242"
     CDS             6179..7063
                     /locus_tag="ACHBV5_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM9966114.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7063..7896
                     /locus_tag="ACHBV5_000243"
     CDS             7063..7896
                     /locus_tag="ACHBV5_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM9966115.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            7914..10007
                     /gene="nanB"
                     /locus_tag="ACHBV5_000244"
     CDS             7914..10007
                     /gene="nanB"
                     /locus_tag="ACHBV5_000244"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HFM9966116.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWRYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10019..11122
                     /locus_tag="ACHBV5_000245"
     CDS             10019..11122
                     /locus_tag="ACHBV5_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFM9966117.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQLSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            11295..11993
                     /locus_tag="ACHBV5_000246"
     CDS             11295..11993
                     /locus_tag="ACHBV5_000246"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFM9966118.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            12012..13529
                     /locus_tag="ACHBV5_000247"
     CDS             12012..13529
                     /locus_tag="ACHBV5_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFM9966119.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            13654..14982
                     /locus_tag="ACHBV5_000248"
     CDS             13654..14982
                     /locus_tag="ACHBV5_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM9966120.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            15234..16100
                     /locus_tag="ACHBV5_000249"
     CDS             15234..16100
                     /locus_tag="ACHBV5_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM9966121.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            16116..16955
                     /locus_tag="ACHBV5_000250"
     CDS             16116..16955
                     /locus_tag="ACHBV5_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM9966122.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            17227..17679
                     /locus_tag="ACHBV5_000251"
     CDS             17227..17679
                     /locus_tag="ACHBV5_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HFM9966123.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            17776..18120
                     /locus_tag="ACHBV5_000252"
     CDS             17776..18120
                     /locus_tag="ACHBV5_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966124.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     HDKIPNNGRINF"
     gene            18130..18429
                     /locus_tag="ACHBV5_000253"
     CDS             18130..18429
                     /locus_tag="ACHBV5_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966125.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFDEHTWSTILIASLFGV
                     YDYKPIDKNRKKSKRKKKKEKIDLFMVGTYESFTDKKENSLQRKMMEEQTWHKKE"
     gene            18411..19055
                     /locus_tag="ACHBV5_000254"
     CDS             18411..19055
                     /locus_tag="ACHBV5_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFM9966126.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            19224..20141
                     /locus_tag="ACHBV5_000255"
     CDS             19224..20141
                     /locus_tag="ACHBV5_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HFM9966127.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            20159..21043
                     /locus_tag="ACHBV5_000256"
     CDS             20159..21043
                     /locus_tag="ACHBV5_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFM9966128.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(21059..21910)
                     /locus_tag="ACHBV5_000257"
     CDS             complement(21059..21910)
                     /locus_tag="ACHBV5_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFM9966129.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            22110..24167
                     /gene="pbp2b"
                     /locus_tag="ACHBV5_000258"
     CDS             22110..24167
                     /gene="pbp2b"
                     /locus_tag="ACHBV5_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HFM9966130.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            24178..24774
                     /gene="recR"
                     /locus_tag="ACHBV5_000259"
     CDS             24178..24774
                     /gene="recR"
                     /locus_tag="ACHBV5_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFM9966131.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            24950..25993
                     /locus_tag="ACHBV5_000260"
     CDS             24950..25993
                     /locus_tag="ACHBV5_000260"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFM9966132.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            26077..27450
                     /gene="murF"
                     /locus_tag="ACHBV5_000261"
     CDS             26077..27450
                     /gene="murF"
                     /locus_tag="ACHBV5_000261"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFM9966133.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELGITDLVERKDSLTFKVNFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     RLENEAK"
     gene            27437..28048
                     /locus_tag="ACHBV5_000262"
     CDS             27437..28048
                     /locus_tag="ACHBV5_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HFM9966134.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKFLDGQFQEN
                     QEIADLQFFAIDQLPALSEKRITKEQIEILWQVYQGQREQYLD"
     gene            28139..28843
                     /locus_tag="ACHBV5_000263"
     CDS             28139..28843
                     /locus_tag="ACHBV5_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HFM9966135.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            29062..30435
                     /gene="ftsA"
                     /locus_tag="ACHBV5_000264"
     CDS             29062..30435
                     /gene="ftsA"
                     /locus_tag="ACHBV5_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFM9966136.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            30452..31711
                     /gene="ftsZ"
                     /locus_tag="ACHBV5_000265"
     CDS             30452..31711
                     /gene="ftsZ"
                     /locus_tag="ACHBV5_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFM9966137.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            31716..32387
                     /locus_tag="ACHBV5_000266"
     CDS             31716..32387
                     /locus_tag="ACHBV5_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFM9966138.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            32397..32936
                     /locus_tag="ACHBV5_000267"
     CDS             32397..32936
                     /locus_tag="ACHBV5_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFM9966139.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            32936..33199
                     /locus_tag="ACHBV5_000268"
     CDS             32936..33199
                     /locus_tag="ACHBV5_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFM9966140.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            33196..33981
                     /locus_tag="ACHBV5_000269"
     CDS             33196..33981
                     /locus_tag="ACHBV5_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFM9966141.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            33990..34778
                     /gene="divIVA"
                     /locus_tag="ACHBV5_000270"
     CDS             33990..34778
                     /gene="divIVA"
                     /locus_tag="ACHBV5_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HFM9966142.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            35126..37918
                     /gene="ileS"
                     /locus_tag="ACHBV5_000271"
     CDS             35126..37918
                     /gene="ileS"
                     /locus_tag="ACHBV5_000271"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFM9966143.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGETRKFVVAAELLTSLSEK
                     FGWVDVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEYVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPTQDAVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            38330..38692
                     /locus_tag="ACHBV5_000272"
     CDS             38330..38692
                     /locus_tag="ACHBV5_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966144.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            39227..39919
                     /locus_tag="ACHBV5_000273"
     CDS             39227..39919
                     /locus_tag="ACHBV5_000273"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HFM9966145.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            39972..42382
                     /locus_tag="ACHBV5_000274"
                     /pseudo
     CDS             39972..42382
                     /locus_tag="ACHBV5_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase N-terminal domain-containing
                     protein"
     gene            42632..43333
                     /locus_tag="ACHBV5_000275"
     CDS             42632..43333
                     /locus_tag="ACHBV5_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966146.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDVLNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            43335..46043
                     /locus_tag="ACHBV5_000276"
     CDS             43335..46043
                     /locus_tag="ACHBV5_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFM9966147.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQCSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATDQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMSQSAVSSVVQNASAIRLFDSVASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTTKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(46139..46630)
                     /gene="tpx"
                     /locus_tag="ACHBV5_000277"
     CDS             complement(46139..46630)
                     /gene="tpx"
                     /locus_tag="ACHBV5_000277"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HFM9966148.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(46753..47682)
                     /gene="psaA"
                     /locus_tag="ACHBV5_000278"
     CDS             complement(46753..47682)
                     /gene="psaA"
                     /locus_tag="ACHBV5_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HFM9966149.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(47714..48562)
                     /locus_tag="ACHBV5_000279"
     CDS             complement(47714..48562)
                     /locus_tag="ACHBV5_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFM9966150.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(48559..49281)
                     /locus_tag="ACHBV5_000280"
     CDS             complement(48559..49281)
                     /locus_tag="ACHBV5_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFM9966151.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            49572..51464
                     /gene="pepO"
                     /locus_tag="ACHBV5_000281"
     CDS             49572..51464
                     /gene="pepO"
                     /locus_tag="ACHBV5_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HFM9966152.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(51587..52216)
                     /locus_tag="ACHBV5_000282"
     CDS             complement(51587..52216)
                     /locus_tag="ACHBV5_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFM9966153.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            53232..55454
                     /locus_tag="ACHBV5_000283"
     CDS             53232..55454
                     /locus_tag="ACHBV5_000283"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFM9966154.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYPSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            55484..55927
                     /gene="dtd"
                     /locus_tag="ACHBV5_000284"
     CDS             55484..55927
                     /gene="dtd"
                     /locus_tag="ACHBV5_000284"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFM9966155.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKRGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(56194..56379)
                     /locus_tag="ACHBV5_000285"
     CDS             complement(56194..56379)
                     /locus_tag="ACHBV5_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966156.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(56398..56811)
                     /locus_tag="ACHBV5_000286"
     CDS             complement(56398..56811)
                     /locus_tag="ACHBV5_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966157.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(56942..57589)
                     /locus_tag="ACHBV5_000287"
     CDS             complement(56942..57589)
                     /locus_tag="ACHBV5_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0034257 - nicotinamide riboside
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0034258 - nicotinamide riboside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HFM9966158.1"
                     /translation="MVVGIAIASGYLNSHLDKFVDWGSWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWEASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
BASE COUNT        17759 a        10355 c        12764 g        16856 t
ORIGIN      
        1 ttctgattgt gagcttgatt atatttccca ttatttctac aagtatttat gcttatgaaa
       61 agctatttga aaaagtgttc gataaggatt gagcaggaag tatggtataa atagcataag
      121 ctgatgtcca tcatttgctt ataaagagat attttagttt aattgcagcg gtgtcctggt
      181 agataaacta gattggcagg agtctgattg gagaaaggag aggggaaaat tggcaccaat
      241 ttgagatagt ttgtttagtt catttttgtc atttaaatga actgtagtaa aagaaagtta
      301 ataaaagaca aactaagtgc attttctgga gtaaatgtct tatttcagaa atcgggatat
      361 agatatagag aggatcagta tgaatcggag tgttcaagaa cgtaagtgtc gttatagcat
      421 taggaaacta tcggtaggag cggtttctat gattgtagga gcagtggtat ttggaacgtc
      481 tcctgtttta gctcaagaag gggcaagtga gcaacctctg gcaaatgaaa ctcaactttc
      541 gggggagagc tcaaccctaa ctgatacaga aaagagccag ccttcttcag agactgaact
      601 ttctggcaat aagcaagaac aagaaaggaa agataagcaa gaagaaaaaa ttccaagaga
      661 ttactatgca cgagatttgg aaaatgtcga aacagtgata gaaaaagaag atgttgaaac
      721 caatgcttca aatggtcaga gagttgattt atcaagtgaa ctagataaac taaagaaact
      781 tgaaaacgca acagttcaca tggagtttaa gccagatgcc aaggccccag cattctataa
      841 tctcttttct gtgtcaagtg ctactaaaaa agatgagtac ttcactatgg cagtttacaa
      901 taatactgct actctagagg ggcgtggttc ggatgggaaa cagttttaca ataattacaa
      961 cgatgcaccc ttaaaagtta aaccaggtca gtggaattct gtgactttca cagttgaaaa
     1021 accgacagca gaattgccaa atggtcgagt tcgcctgtat gttaatggtg ttttatctcg
     1081 aacaagtctg aaatctggca atttcattaa agatatgcca gatgtaacgc atgtgcaaat
     1141 cggagcaacc aagcgtgcca acaatacggt ttgggggtca aatctacaga ttcggaatct
     1201 cactgtgtat aatcgtgctt taacaccaga agaggtacaa aaacgtagtc aactttttaa
     1261 acgctcagat ttagaaaaaa aactacctga aggagcggct ttaacagaga aaacggacat
     1321 attcgaaagc gggcgtaacg gtaaaccaaa taaagatgga atcaagagtt atcgtattcc
     1381 agcacttctc aagacagata aaggaacttt gatcgcaggt gcagatgaac gccgtctcca
     1441 ttcgagtgac tggggtgata tcggtatggt catcagacgt agtgaagata atggtaaaac
     1501 ttggggtgac cgagtaacca ttaccaactt acgtgacaat ccaaaagctt ctgacccatc
     1561 gatcggttca ccagtgaata tcgatatggt gttggttcaa gatcctgaaa ccaaacgaat
     1621 cttttctatc tatgacatgt tcccagaagg gaagggaatc tttggaatgt cttcacaaaa
     1681 agaagaagcc tacaaagaaa tcgatggaaa aacctatcaa atcctctatc gtgagggaga
     1741 aaaggaagct tataccattc gagaaaatgg tactgtctat acaccagatg gtaaggcgac
     1801 agactatcgc gttgttgtag atcctgttaa accagcctat agcgacaagg gtgatctata
     1861 caagggtgac caattactag gaaatatcta cttcacaaca aacaaaactt ctccatttag
     1921 aattgccaag gatagctatc tatggatgtc ctacagtgat gacgacggga agacatggtc
     1981 agcgcctcaa gatattactc cgatggtcaa agccgattgg atgaaattct tgggtgtagg
     2041 tcctggaaca ggaattgtac ttcggaatgg gcctcacaag ggacggattt tgataccggt
     2101 ttatacgact aataatgtat ctcacttaaa tggctcgcaa tcttctcgtg tcatctattc
     2161 agatgatcat ggaaaaactt ggcatgctgg agaagcggtc aacgataacc gtcaggtaga
     2221 cggtcaaaag atccactctt ctacgatgaa caataaacgt gcgcaaaata cagaatcaac
     2281 ggtggtacaa ctaaacaatg gagatgttaa actctttatg cgtggtttga ctggagatct
     2341 tcaggttgct acaagtaaag acggaggagt gacttgggag aaggatatca aacgttatcc
     2401 acaggttaaa gatgtctatg ttcaaatgtc tgctatccat acgatgcacg aaggaaaaga
     2461 atacatcatc ctcagtaatg caggtggacc gaaacgtgaa aatgggatgg tccacttggc
     2521 acgtgtcgaa gaaaatggtg agttgacttg gctcaaacac aatccaattc aaaaaggaga
     2581 gtttgcctat aattcgctcc aagaattagg aaatggggag tatggcatct tgtatgaaca
     2641 tactgaaaaa ggacaaaatg cctataccct atcatttaga aaatttaatt gggaattttt
     2701 gagcaaaaat ctgatttctc ctaccgaagc gaaagtgaag cgaactagag agatgggcaa
     2761 aggagagatg ggcaaaggag ttattggctt ggagttcgac tcagaagtat tggtcaacaa
     2821 ggctccaacc cttcaattgg caaatggtaa aacagcgact ttcctaaccc agtatgatag
     2881 caagaccttg ttgtttgcag tagataagga agatatcgga caggaaatta ttggtatagc
     2941 taaaggaagc atcgaaagta tgcataatct tcctgtaaat ctagcaggtg ccagagttcc
     3001 tggcggagta aatggtagca aagcagcggt gcatgaagtt ccagaattta cagggggagt
     3061 taatggtaca gagccagctg ttcatgaaat cgcagagtat aagggatctg attcgcttgt
     3121 aactcttact acaaaagaag attatactta caaagctcct cttgctcagc aggcacttcc
     3181 tgaaacagga aacaaggaga gtgacctcct agcttcacta ggactaacag ctttcttcct
     3241 tggtctgttt acgctaggga aaaagagaga acaataagag aagaattcta aacatttgat
     3301 tttgtaaaaa tagaaggaga tagcaggttt ttaagcctgc tatctttttt tgatgacatt
     3361 caggctgata cgaaatcata agaggtctga aactactttc agagtagtct gttctataaa
     3421 atatagtaga ttgaaataag atgtgaacaa ctctatcagg aaagtcaaat taatttatag
     3481 aaaaatttta gcagtcaagg tgtactgtta taaattcaat atattatacg actattaacc
     3541 ttatcttctc ctaaaattga ctttcttgtt ttcttatctt gtctactcga aacaagtatt
     3601 gtaagaattt gattattttt gaaagtactt ttaatatact tgatatagtt aaaaaagatt
     3661 tgaaactaaa ttccaaatta gaaaaagact tgaaatacta aaaaaaaaaa gtatactcta
     3721 attgaaaacg gtaacaaaac taatttagag aatgaaatat agagtatttc tctcttaaaa
     3781 gtttttggtg aaacgagatg tagaaaggag atttagccaa agagtctatt agtgctagaa
     3841 taatagatta gaattatttt agaaaaacga agtgagcagc ttataaattc aagtccccaa
     3901 atagattcat actagtatct tttgcaaaaa ataaagggcg acttccttca tgaatatcaa
     3961 tttcatctat aaggaaggta gctaattgaa ctaacttatt tattctgttt gtcgctagaa
     4021 aaatcagacc tccttgtgaa gattgaggag atactgaatg aaaatcaaag aagaaactag
     4081 caagctagta gcagattgcc caaaacaccg ctttgaggtt gtagataaga ctgacgtata
     4141 taatccaagg tgaagcgact gtggtttgaa gagattttca aagagtatag gctagagagt
     4201 agtgttttta tgtccttcta gtagaaaatg ctagacagaa gaatggggaa cttggatagg
     4261 aaaaatagat tgagaaagga ggttagaaga gatgattatt acaaaaatta gccgtttagg
     4321 aacttatgtg ggagtaaatc cacattttgc aacattaata gattttttag aaaaaacagg
     4381 actagaaaat ttaacagaag gttcgattgc tatcgatggt aatcgattgt ttgggaattg
     4441 ctttacttat ctagcagatg gtcaagcagg ggctttcttt gaaacacacc aaaaatattt
     4501 ggatattcat ttagttttgg aaaacgaaga agccatggct gttacatcgc cggaaaatgt
     4561 aagcgttacc caagaatatg atgaagagaa agatattgaa ttatacacag ggaaagtgga
     4621 acagttggtt catttgagag ctggtgaatg cctcatcact tttccagaag atttacatca
     4681 acccaaggtt cgtataaatg atgaacctgt gaaaaaagtt gtctttaaag ttgcgatttc
     4741 ttaatgtaga aagagaagaa cgatgaaaaa aatgagaaag tttttatgtc tagctggaat
     4801 tgcgctagcg gctgttgcct tggtagcttg ttcaggaaaa aaagaagcta caactagtac
     4861 tgaaccacca acagaattat ctggtgagat tacaatgtgg cactccttta ctcaaggacc
     4921 ccgtttagaa agtattcaaa aatcagcaga tgctttcatg caaaagcatc caaaaacgaa
     4981 aatcaagatt gaaacatttt cttggaatga cttctatact aaatggacta caggtttagc
     5041 aaatggaaat gtgccagata tcagtacagc tcttcctaac caagtaatgg aaatggtcaa
     5101 ctcagatgct ttggttccgc taaatgattc tatcaagcgt attggacaag ataaatttaa
     5161 cgaaactgcc ttaaatgaag caaaaatcgg agatgattac tactctgttc ctctttattc
     5221 acatgcacaa gtcatgtggg ttagaacaga tttgttaaaa gaacataata ttgaggttcc
     5281 taaaacttgg gatcaactct atgaagcttc taaaaaattg aaagaagctg gagtttatgg
     5341 cttgtctgtt ccgtttggaa caaatgactt aatggcaaca cgtttcttga acttctacgt
     5401 acgtagtggt ggaggaagcc tcttaacaaa agatcttaaa gcagacttga caagccaact
     5461 tgctcaagat ggtattaaat actgggttaa attgtataaa gaaatctcac ctcaagattc
     5521 tttgaacttt aatgtccttc aacaagctac cttgttctat caaggaaaaa cagcatttga
     5581 ctttaactct ggcttccata tcggaggaat taatgccaac agtcctcaat tgattgattc
     5641 gattgatgct tatcctattc caaaaatcaa agagtctgat aaagaccaag gaattgaaac
     5701 ctcaaacatt ccaatggttg tttggaaaaa ttcaaaacat ccagaagttg ctaaagcatt
     5761 cttagaagca ctttataatg aagaagacta cgttaaattc cttgattcaa ctccagtagg
     5821 tatgttgcca actattaagg ggattagcga ttctgcagcc tataaagaaa atgaaactcg
     5881 taagaaattt aaacatgctg aagaagtaat tactgaagct gttaaaaaag gtactgctat
     5941 tggttatgaa aatggaccaa gtgtacaagc tggtatgtta actaaccaac acattattga
     6001 acaaatgttc caagatatca ttacaaatgg aacagatcct atgaaagcag caaaagaagc
     6061 agaaaaacaa ttaaacgatt tatttgaggc tgttcagtag atgtaaaaga ctagaaaata
     6121 ggtgggctag tgagctgaaa agctctagcc caatcttgta aaagaaggga gaaggagaat
     6181 ggttaaagaa cgtaatttaa ctcgctggat atttgttttg ccagctatga ttatcgtagg
     6241 attactcttt gtttatccgt ttttctcgag tattttttat agctttacca ataagcattt
     6301 gattatgcct aattataaat ttgttggttt ggctaactat aaagctgtgc tgtcagatcc
     6361 caacttcttt aatgcgttct ttaattcaat taagtggacc gttttctcat tagttggtca
     6421 agttttagta gggtttgtat tggctttagc tcttcacaga gtacgccact tcaagaaatt
     6481 atataggacc ttattgattg ttccttgggc atttcctacc atcgttattg ccttctcttg
     6541 gcagtggatt ctaaacgggg tttatggcta cttacctaat ctaatcgtaa aattaggttt
     6601 aatggaacat acacctgcat ttttgacaga tagtacatgg gcattcctat gtttggtgtt
     6661 tatcaacatt tggtttggag caccaatgat tatggttaat gtgctttcag ctttgcaaac
     6721 agtaccagaa gaacaatttg aggctgctaa gatagatggt gcttcaagtt ggcaggtgtt
     6781 caagtttatc gtctttccac atattaaagt ggttgtagga cttctagttg ttttgagaac
     6841 tgtatggatc tttaataact ttgacattat ctacctcatt actggtggtg gaccagccaa
     6901 tgctacaacg acacttccaa tttttgctta caacctgggt tggggaacta aattgttggg
     6961 tcgtgcttca gcagttacag tattgctctt tatcttcttg gtggcgattt gctttatcta
     7021 ctttgctatc atcagtaagt gggaaaagga gggtagaaaa taatgaagaa gaaatccagt
     7081 atttatttag atattctctc acatgtactt ttagttggtg cgaccatcgt tgcaattttc
     7141 ccattggtat ggattatcat atcttctgtc aaagggaaag gggaattaac tcagtatcca
     7201 acacgatttt ggcctgaaca gtttacatta gattatttca ctcatgttat caacgatttg
     7261 cacttcattg ataacattcg aaacagttta atcattgcct tggctacaac cctcattgcg
     7321 attattattt ctgctatggc agcctatggt attgttcgat tctttcctaa attgggagca
     7381 atcatgtcga gactactcgt cattacctac attttcccac caattttgtt agcaattccc
     7441 tattcaattg ccattgctaa agttgggtta acaaatagtt tatttggctt gatgatggtt
     7501 tatctatctt ttagtgttcc atatgcagtt tggctcttag ttggattttt ccaaacagtt
     7561 ccaattggaa ttgaagaagc ggctagaatt gatggtgcaa ataaatttgt tacgttttat
     7621 aaggttgtgc taccgattgt agcaccaggt attgtagcaa cagctattta tacatttatc
     7681 aatgcttgga atgaattcct gtatgccttg attttaatta acaatacagg aaagatgaca
     7741 gtagcagtag cccttcgttc acttaatggt tcagaaatac tagactgggg agatatgatg
     7801 gcagcgtctg ttattgtagt tcttccatca attattttct tctctatcat ccaaaataag
     7861 attgcaagtg gattatcaga aggatctgtg aagtagacga aagaaggaaa aaaatgaata
     7921 aaagaggtct ttattcaaaa ctaggaattt ctgttgtagg cattagtctt ttaatgggag
     7981 tccccacttt gattcatgcg aatgaattaa actatggtca actgtccata tctcctattt
     8041 ttcaaggagg ttcatatcaa ctgaacaata agagtataga tatcagctct ttgttattag
     8101 ataaattgtc tggagagagt cagacagtag taatgaaatt taaagcagat aaaccaaact
     8161 ctcttcaagc tttgtttggc ctatctaata gtaaagcagg ctttaaaaat aattactttt
     8221 caattttcat gagagattct ggtgagatag gtgtagaaat aagagacgcc caaaagggaa
     8281 taaattattt attttctaga ccagcttcat tatggggaaa gcataaagga caggcagttg
     8341 aaaatacact agtatttgta tctgattcta aagataaaac atacacaatg tatgttaatg
     8401 gaatagaagt gttctctgaa acagttgata catttttgcc aatttcaaat ataaatggta
     8461 tagataaggc aacactagga gctgttaatc gtgaaggtaa ggaacattac ctcgcaaaag
     8521 gaagtattgg tgaaatcagt ctatttaaca aagcaattag tgatcaggaa gtttcaaata
     8581 ttcccttgtc aaatccattt cagttaattt tccaatcagg agattctact caagctaact
     8641 attttagaat accgacacta tatacattaa gtagtggaag agttctatca agtattgatg
     8701 cacgttatgg tgggactcat gattctaaaa gtaagattaa tattgccact tcttatagtg
     8761 atgataatgg gaaaacgtgg agtgagccaa tttttgctat gaagtttaat gactatgagg
     8821 agcagttagt ttactggcca cgagataata aattaaagaa tagtcaaatt agtggaagtg
     8881 cttcattcat agattcatcc attgttgaag ataaaaaatc tgggaaaacg atattactag
     8941 ctgatgttat gcctgcgggt attggaaata ataatgcaaa taaagccgac tcaggtttta
     9001 aagaaataaa tggtcattat tatttaaaac taaagaagaa tggagataac gatttccgtt
     9061 atacagttag agaaaatggt gtcgtttatg atgaaacaac taataaacct acaaattata
     9121 ctataaatga taagtatgaa gttttggagg gaggaaagtc tttaacagtc gaacaatatt
     9181 cggttgattt tgatagtggc tctttaagag aaaggcataa tggaaaacag gttcctatga
     9241 atgttttcta caaagattcg ttatttaaag tgactcctac taattatata gcaatgacaa
     9301 ctagtcagaa tagaggagag agttgggaac aatttaagtt gttgcctccg ttcttaggag
     9361 aaaaacataa tggaacttac ttgtgtcctg gacaaggttt agcattaaaa tcaagtaaca
     9421 gattgatttt tgcaacatat actagtggag aactaaccta tctcatttcg gatgatagtg
     9481 gtcaaacatg gaagaaatcc tcagcttcaa ttccgtttaa aaatgcaaca gcagaagcac
     9541 aaatggttga actgagagat ggtgtgatta gaacattctt tagaaccact acaggtaaga
     9601 tagcttatat gactagtaga gattctggag aaacatggtc gaaagtttcg tatattgatg
     9661 gaattcaaca aacttcatat ggcacacaag tatctgcaat taaatactct caattaattg
     9721 atggaaaaga agcagtcatt ttgagtacac caaattctag aagtggccgt aagggaggcc
     9781 aattagttgt cggtttggtc aataaagaag atgatagtat tgattggaga taccactatg
     9841 atattgattt gccttcgtat ggttatgcct attctgcgat tacagaattg ccaaatcatc
     9901 acataggtgt actgtttgaa aaatatgatt cgtggtcgag aaatgaattg catttaagca
     9961 atgtagttca gtatatagat ttggaaatta atgatttaac aaaataaagg agaaaaacat
    10021 ggttaaatac ggtgttgttg gagcagggta ttttggagct gaattggctc gctacatgca
    10081 aaagaatgat ggagcagaga ttactcttct ctatgatcca gataatgcag aggcgattgc
    10141 agaagaattg ggagcaaaag tagcaagttc cttagatgag ttggtttcta gcgatgaagt
    10201 agattgtgtt atcgtcgcaa ctccaaataa tcttcataag gaaccggtta ttaaggctgc
    10261 acagcatggt aaaaatgttt tctgtgaaaa accaattgcg ctttcttatc aagattgtcg
    10321 cgagatggta gatgcgtgta aagaaaacaa tgtaaccttt atggcaggac atattatgaa
    10381 tttctttaat ggtgttcatc atgcaaaaga actcattaat caaggagtta tcggagacgt
    10441 tctatattgt catacagctc gtaatggttg ggaagaacaa caactgtcag tatcatggaa
    10501 aaaaattcgt gaaaaatcag gtggtcactt gtatcaccac atccatgaat tggattgcgt
    10561 tcaattcctt atggggggca tgcctgaaac tgtaaccatg acaggtggaa atgtggccca
    10621 tgaaggtgaa catttcggtg atgaagatga tatgattttt gtcaatatgg aattttctaa
    10681 taagcgtttt gccttgttag aatggggttc agcttatcgt tggggtgaac attatgtctt
    10741 aatccaagga agcaaaggtg ccatccgctt agacttattc aactgtaaag gaactcttaa
    10801 gctagatggg caagaaagct atttcttgat tcacgaatcg caagaagaag atgatgatcg
    10861 gactcgtatc tatcatagta cagagatgga tggagcaatt gcttatggta aaccaggtaa
    10921 acgtactcca ttatggctat catctgtcat tgataaagaa atgcgctatc tgcatgagat
    10981 tatggaagga gctccagtat cagaagaatt tgcaaaactt ttgacaggtg aagctgccct
    11041 agaagcaatt gctactgcag atgcttgtac ccagtctatg tttgaagatc gcaaagtaaa
    11101 attgtcagaa attgtaaaat aaattttggt attctcctat tataggtcga cttgctcctc
    11161 tgaaagtact tttagaggag ctgtttgact tggctagttt ttgaaactga aatctattat
    11221 actacaaact attgaaagcg ttttaatttt aaggtataat aatctcatag aaataaagaa
    11281 aaggaggaaa gaggatgcca cagattagca aagaagcctt gattgagcaa atcaaagatg
    11341 gaatcatcgt ttcttgtcag gctcttcctc atgaaccgct ttatacagaa gcgggagggg
    11401 tgattccctt gctggtcaaa gcggctgagc aaggtggagc agtcggtatc cgagcaaaca
    11461 gtgttcgcga tatcaaggaa attaaggaag tcactaaact tccaatcatt gggattatca
    11521 aacgtgatta tccacctcag gaacccttca tcacggctac tatgaaagaa gttgatgaat
    11581 tggcagaact ggacatcgag gtgattgctc tggattgtac caagcgtgaa cgctacgatg
    11641 gtttggaaat tcaagagttc attcgtcagg ttaaggagaa atatcctaat cagcttttga
    11701 tggctgatac tagtatcttc gaagaagggc tagcagctgt agaagcagga attgactttg
    11761 tcggaacaac cttatcaggc tacacatcct acagtccaaa agtagacggt ccagattttg
    11821 aattgattaa gaaactctgt gatgccggtg tagatgtcat tgcagaagga aaaattcata
    11881 caccagaaca agccaaacaa atccttgaat atggagtgcg aggcatcgtt gttggtggcg
    11941 ccattactag accaaaagag attacagaac gcttcgttgc tagtcttaaa taagatgtga
    12001 gggggagttt tatgtttaaa gttttacaaa aagttggaaa agcttttatg ttacctatag
    12061 ctatacttcc tgcagcaggt ctacttttgg ggattggtgg tgcactttca aacccaacca
    12121 cgatagcaac ttatccaata ctagacaata gtatttttca atcaatattc caagtaatga
    12181 gctctgcagg agaggttgta ttcagtaatt tgtcactact tctctgtgtg ggattatgta
    12241 ttggcttagc gaaacgagat aaaggaaccg ctgcgttagc aggagtaact ggttacttag
    12301 ttatgactgc aacgatcaaa gctttggtaa aactttttat ggcagaagga tctgcaattg
    12361 atactggagt tattggagca ttagttgtcg gaatagttgc cgtatatttg cacaaccgat
    12421 ataacaatat tcaattacct tccgctttag gattctttgg aggttcacgc ttcgttccta
    12481 ttgttacatc gttctcttct atcttgattg gctttgtctt ctttgttatt tggccacctt
    12541 tccaacaact tcttgtttct acaggtggat atatttctca ggcgggtcca attggaactt
    12601 ttctatatgg atttttaatg agactttctg gagcagtagg cttacatcat ataatttacc
    12661 ctatgttttg gtatactgaa cttggtggtg ttgaaactgt tgcaggacaa acagtggttg
    12721 gagctcaaaa aatatttttt gctcaattag ccgatccggc ccattctgga ttatttacag
    12781 aaggaacaag gttttttgca ggtcgtttct caacaatgat gttcggttta ccggctgcct
    12841 gtttagcgat gtaccatagt gttcctaaaa atcgtcgtaa aaaatacgcg ggtttgtttt
    12901 ttggagttgc tttaacatct tttattaccg gtattacaga accaattgaa tttatgtttc
    12961 tattcgtcag tccggttcta tatgttgttc acgcattcct tgatggtgtt agcttcttta
    13021 ttgcagacgt cttaaatatt tcaataggaa acacattttc aggaggtgta atcgatttca
    13081 ctttatttgg aattttgcag gggaacgcta agacgaattg ggttcttcag attccaattg
    13141 gacttatttg gagtgttttg tattatatta tttttagatg gttcattact caattcaacg
    13201 ttctaacgcc aggacgagga gaagaagtag attctaaaga aatttctgaa tccgcagatt
    13261 caacttcaaa tactgcagat tatttaaaac aggatagcct acaaattatc agagccttgg
    13321 gtggatcaaa taatatagaa gatgtagatg cttgtgtgac acgtttacgt gtagctgtaa
    13381 aagaagttaa tcaagttgat aaagcacttt taaaacaaat tggtgcagtt gatgtcttag
    13441 aagtgaaggg tggcattcaa gcaatctatg gagcaaaagc aatcttatat aaaaatagta
    13501 ttaatgaaat tttaggtgta gatgattaag tacttactga cttaataaaa aacagaggag
    13561 agtgatggat gagtaggatg aaatgaaatc gcatacaaga aataaagaac tcattatcca
    13621 agttggatac gcttattaca taggagaata caaatgaaat ttagaaaatt agcttgtaca
    13681 gtacttgcgg gtgctgcggt tcttggtctt gctgcttgtg gcaattctgg cggaagtaaa
    13741 gatgctgcca aatcaggtgg tgacggtgcc aaaacagaaa tcacttggtg ggcattccca
    13801 gtatttaccc aagaaaaaac tggtgacggt gttggaactt atgaaaaatc aatcatcgaa
    13861 gcgtttgaaa aagcaaaccc agatataaaa gtgaaattgg aaaccatcga cttcaagtca
    13921 ggtcctgaaa aaatcacaac agccatcgaa gcaggaacag ctccagacgt actctttgat
    13981 gcaccaggac gtatcatcca atacggtaaa aacggtaaat tggctgagtt gaatgacctc
    14041 ttcacagatg aatttgttaa agatgtcaac aatgaaaaca tcgtacaagc aagtaaagct
    14101 ggagacaagg cttatatgta tccgattagt tctgccccat tctacatggc aatgaacaag
    14161 aaaatgttag aagatgctgg agtagcaaac cttgtaaaag aaggttggac aactgatgat
    14221 tttgaaaaag tattgaaagc acttaaagac aagggttaca caccaggttc attgttcagt
    14281 tctggtcaag ggggagacca aggaacacgt gcctttatct ctaaccttta tagcggttct
    14341 gtaacagatg aaaaagttag caaatataca actgatgatc ctaaattcgt caaaggtctt
    14401 gaaaaagcaa ctagctggat taaagacaat ttgatcaata atggttcaca atttgacggt
    14461 ggggcagata tccaaaactt tgccaatggt caaacatctt acacaatcct ttgggcacca
    14521 gctcaaaatg gtatccaagc taaactttta gaagcaagta aggtagaagt ggtagaagta
    14581 ccattcccat cagacgaagg taagccagct cttgaatacc ttgtaaacgg gtttgcagta
    14641 ttcaacaata aagacgacaa gaaagtcgct gcatctaaga aattcatcca gtttatcgca
    14701 gatgacaagg agtggggacc taaagacgta gttcgtacag gtgctttccc agtccgtact
    14761 tcatttggaa aactttatga agacaaacgc atggaaacaa tcagcggctg gactcaatac
    14821 tactcaccat actacaacac tattgatgga tttgctgaaa tgagaacact ttggttccca
    14881 atgttgcaat ctgtatcaaa tggtgacgaa aaaccagcag atgctttgaa agccttcact
    14941 gaaaaagcga acgaaacaat caaaaaagct atgaaacaat agtccttagt tattctataa
    15001 aaagtagttt tttaaagaac ctaagagtgt ataccccctt ttccctctac acagatagtg
    15061 taagaaaagg gggcttttgt ttaaaatgta agaaactgtc acgaaattaa aatgaagttc
    15121 ttacataagc gaatcataaa aaatttcatt ttgattttaa aacagttcaa gaaagtcaaa
    15181 aaattattct atttgaaaga gaggtgccga ctgtgaaagt caataaaatc cgtatgcggg
    15241 aaacagtgat ttcctacgct ttcctagcac cagtattatt cttctttgtc atctttgtgt
    15301 tggctccgat ggtgatgggc ttcattacaa gtttctttaa ctactcaatg actaaatttg
    15361 agtttgtagg cttggataac tatatccgta tgtttaaaga tcctgtcttt acaaaatctc
    15421 tgattaacac agttattttg gttattggat ctgtaccagt tgttgttcta ttctcactct
    15481 ttgtagcatc tcagacctat catcaaaatg tcattgccag atccttctac cgtttcgtct
    15541 tcttccttcc tgttgtaacg ggtagtgttg ccgtgacagt tgtttggaaa tggatttatg
    15601 acccactatc agggattcta aactttgtcc ttaagtccag ccacatcatc agccaaaaca
    15661 tttcttggtt gggagataaa aactgggcat tgatggcgat tatgattatt ctcttgacca
    15721 cttcagttgg tcagcccatc atcctttata tcgctgccat ggggaatatt gacaattcac
    15781 tggttgaagc ggcgcgtgtt gatggtgcaa ctgagtttca agttttttgg aagattaaat
    15841 ggccaagcct tcttccaaca actctttata ttgcaatcat cacaacaatt aactcattcc
    15901 agtgttttgc cttgattcag cttttgacat ctggtggtcc aaactactca acaagtacct
    15961 tgatgtacta cctttacgaa aaagccttcc aattgacaga atacggctat gccaacacaa
    16021 ttggtgtctt cttggcagtc atgattgcta tcgtaagctt tgttcaattt aaagtacttg
    16081 gaaacgacgt agaatactaa agaaaggaga cagctatgca atctacagaa aaaaaaccat
    16141 taacagcctt tactgttatt tcaacaatca ttttgctctt gttgactgtg ctgttcatct
    16201 ttccattcta ctggattttg acaggggcat tcaaatcaca acctgataca attgttattc
    16261 ctcctcagtg gttccctaaa atgccaacca tggaaaactt ccaacaactc atggtgcaga
    16321 accctgcctt gcaatggatg tggaactcag tatttatctc attggtaacc atgttcttag
    16381 tttgtgcaac ctcatctcta gcaggttatg tattggctaa aaaacgtttc tatggtcaac
    16441 gcattctatt tgctatcttt atcgctgcta tggcgcttcc aaaacaagtt gtccttgtac
    16501 cattggtacg tatcgtcaac ttcatgggaa tccacgatac tctctgggca gttatcttgc
    16561 ctttgattgg atggccattc ggtgtcttcc tcatgaaaca atttagtgaa aatattccta
    16621 cagagttgct tgaatcagct aaaatcgacg gttgtggtga gattcgtacc ttctggagtg
    16681 tagccttccc gattgtgaaa ccagggtttg cagcccttgc aatctttacc ttcatcaata
    16741 cttggaatga ctacttcatg caattggtaa tgttgacttc acgtaacaat ttgaccatct
    16801 cacttggggt tgcgaccatg caggctgaaa tggcaaccaa ctatggtttg attatggcag
    16861 gagctgccct tgctgctgtt ccaatcgtca cagtcttcct agtcttccaa aaatccttca
    16921 cacagggtat tactatggga gcggtcaaag gataatactc tgagaaaatc tcttcaaact
    16981 acgtcagcgt caccttgcca tacttaagta ttgcctgcgg ttagcttcct agtttgttct
    17041 tcaattttca ttgagtatag gaaaatcaat ctatcaagat acagaagtat attttataga
    17101 tttagagaat atagaggtta taagtgtcta caaaatggag ggtatgcagt tactttatga
    17161 agttttgtca gacacttata aacttaagaa tggttttagt taactatcag aaacgaagga
    17221 aagagtatga tttttgacga tttgaaaaac atcacctttt acaaagggat tcatcctaat
    17281 ttagacaagg ctatcgacta tctctaccaa catcgtaagg attctttcga attaggaaag
    17341 tatgatattg atggagataa agtctttcta gttgttcagg aaaatgtcct caatcaagct
    17401 gaaaatgatc aatttgagta tcataagaac tatgcagatt tgcatttgct ggtagaagga
    17461 catgaatatt cgagctacgg ttcacgtatc aaagacgagg cagtagcatt cgacgaagcg
    17521 agtgacattg gctttgttca ttgtcatgaa cactacccac tcttgttggg ttatcacaat
    17581 tttgcgattt tcttcccagg tgagccacat cagccaaatg gttatgcagg catggaagaa
    17641 aaggttcgga aatatctctt taaaattttg attgattaaa aataggatga attgtttttt
    17701 tgtaaagctt tgacaatact ctaccatgaa attgatcttt gtgaggtagg gaaatgagaa
    17761 taaaatattt aaaaattggt atcttctaag tatgctgcaa gagctagttt cttggatgga
    17821 cagggaatta cagttgatga gatggcttgg ataattaggg gcattgtgaa tggattgatt
    17881 ggtagataca taaaattagg tacttatgca gccaagtatg gtattagtat ggcgcgttcg
    17941 atcttaagta gggcagctgc aactgcagca gcaagagtag gattatcgac caagatttct
    18001 ggatggattt tacgagtagc tgtgaatgta gctgatgtat atggtaattt tgccaacaat
    18061 attgctgcag cttgggatgc acatgataaa attcctaaca atggtcgtat aaacttttaa
    18121 aatgcgagaa tgaaagcact ttgtattttt ttattgaata tgttagcttg gacagtgctt
    18181 gcaatgataa ttcgtggagg gctagatgga tttgatgagc atacttggag tactatttta
    18241 attgcttcgc tgttcggggt atatgattat aagcccatag ataaaaatag aaaaaagtcc
    18301 aaaagaaaaa agaaaaaaga aaaaatagat ttgttcatgg tagggactta tgaaagcttt
    18361 actgacaaaa aagaaaacag tttacaaaga aaaatgatgg aggagcaaac atggcacaaa
    18421 aaggagtaag ccttatcaag gcagcatttg atacagacaa ctttctcatg cgttttagtg
    18481 agaaagtctt ggacatcgtg acagccaatc ttctttttgt cgtctcttgt ttgcccatcg
    18541 tgacgattgg agtggctaaa atcagcctct acgagaccat gttcgaagtt aagaagagca
    18601 gacgggtgcc tgtttttaaa atctatctaa gatctttcaa gcaaaatctg aaactaggtc
    18661 ttcagctggg tttaatggag ttaggaattg tgtttcttac cctttcagat ctctatcttt
    18721 tctggggtca aacagctctg cccttccaat tgctgaaagc catttgttta ggtattctga
    18781 tttttcttac tatcgtgatg ctggctagtt accctatcgc ggcacgttat gacctatctt
    18841 ggaaagaaat tcttcaaaaa ggattgatgt tggctagttt taactttcct tggttcttcc
    18901 tcatgttagc cattcttgtc ctcattgtga tggttcttta tctgtccgcc ttcagtctac
    18961 tcttaggtgg ctcagtcttc ttactttttg ggtttggact attggtcttt atccagactg
    19021 gattgatgga gaaaattttc gcaaaatacc aataggagcc ttatttctga aactactttc
    19081 aaacgctcca aacgctattc tataagcgag aaactaaaat ctaagtgtct ataagatatt
    19141 gaaagccttt tcggtaaagt gtatactaaa gaagtaaaga aaaatctgct ttagcagaaa
    19201 ataaaaataa taggagaaaa tctatgtcag atttgaaaaa atacgaaggt gtcattccag
    19261 ccttctacgc atgttatgat gaacaaggag aagtaagccc agaacgtacg cgtgccttgg
    19321 ttcaatactt cattgataaa ggtgttcaag gtctttatgt caatggttct tctggtgaat
    19381 gtatctacca aagtgttgaa gaccgcaagt taatcttgga agaagtcatg gcggtagcca
    19441 aaggtaaatt gaccatcatt gctcatgttg cctgcaacaa tactaaagat agtatggaac
    19501 ttgctcgcca tgctgaaagc ttgggagtag atgctattgc aacgattcca ccaatttatt
    19561 tccgcttgcc agaatactca gttgccaaat actggaacga tatcagttct gcagctccaa
    19621 acacagacta cgtgatttac aacattcctc aattggcagg ggttgctttg actccaagcc
    19681 tttacacaga aatgttgaaa aatcctcgtg ttatcggtgt taagaactct tctatgccag
    19741 ttcaagatat ccaaaccttt gtcagccttg gtggggaaga ccatatcgtc tttaatggtc
    19801 ctgatgagca gttcctagga ggacgcctca tgggtgctag ggctggtatc ggtggtactt
    19861 atggtgctat gccagaactc ttcttgaaac tcaatcagtt gattgcggat aaggacctag
    19921 aaacagcgcg tgaattgcag tatgctatca acgcaatcat tggtaaactc acttctgctc
    19981 atggaaatat gtacggtgtc attaaagaag tcttgaaaat caatgaaggc ttgaatattg
    20041 gatctgttcg ttcaccattg acaccagtga ctgaagaaga tcgtccagtt gtagaagcgg
    20101 ctgctgcctt gattcgtgaa accaaggagc gcttcctcta atctaaaagg aggtatttat
    20161 gacatactac gttgcaattg atatcggtgg aaccaacatc aagtatggtt tggttgatca
    20221 agaggggcaa cttcttgaat cgcatgaaat gccaactgag gcgcataagg gtggacctca
    20281 tatcttacaa aagaccaaag atatcgtagc tagttattta gaaaaaggcc cagtagcagg
    20341 tgttgccata tcttctgctg ggatggtgga tccggataag ggtgagattt tctatgctgg
    20401 gcctcaaatc cctaactacg caggcaccca gttcaaaaag gaaatcgaag aaagctttac
    20461 tattccttgt gagattgaaa atgatgtcaa ctgtgcaggt cttgctgagg cagtatctgg
    20521 ttcaggcaag ggagcaagtg tgacactttg cttgaccatt ggaaccggta tcggtggttg
    20581 cttgattatg gataggaaag tcttccatgg ttttagcaat tcagcctgtg aagtcgggta
    20641 tatgcatatg caggatggag cttttcagga tctcgcttct acaacagctt tagtgaaata
    20701 tgtagctgaa gcccatggag aagatgttga tcagtggaat ggccgacgta tctttaagga
    20761 agctactgaa ggaaacaaaa tctgcatgga aggtattgac cgtatggttg actatctagg
    20821 aaaaggtctg gcaaatattt gttatgtggc caatccagaa gtggttattc ttggtggtgg
    20881 tatcatgggg caagaggcta tcctcaaacc taagatccgc acagccttga aagaggcatt
    20941 ggtaccaagt ttagcagaaa aaacacgatt agaatttgcc catcaccaaa atacagcagg
    21001 gatgttgggt gcatattatc attttaagac aaaacaatcc tagtttggct cagccaaact
    21061 aggattttct tacacgtttt tgtctacgat agccgttgag ttttttattt tcccagtagc
    21121 tattaaagat tttttccttg ctttcgcgat tgatttccaa aaagtaggca taaatcaaat
    21181 cgataaagaa gagcatagga agttgagcgg atattcgttg gatgtaggag ggttggctgt
    21241 gggtggctac aagaacagtc tctgtatagg tctggctatc tttattggga acacttgtaa
    21301 agagtacagt ctttgccccc atctccttgg catctaatag actatctaaa atagaaggag
    21361 ttgagcctga aagtgagaaa cccagtacta gacaattttc atccatgatg ctggttgtcc
    21421 aggcaaagcc gtcttggtct gtcaaagctt cgcagaccac acctagtcgc ataaaacgta
    21481 atttcatttc acgggcgacg aggccagaac tccctgttcc aaagaagtag atacgctcag
    21541 catcttcgat tagctgggca attcgctcta gttggatttc gtcaatcaag tcttgtgttt
    21601 gttccctcat attgctataa cttctgagga ctcgtttggt cagtggacta tgcttggaga
    21661 cttggttggc ttgattttct gcctgatgtt ggtattggaa aataaattct cggtagccag
    21721 taaagccaca ctttttagca aagcgggtca aagcagcttg agaaatatgt aatttttggg
    21781 tgacttgttg agaagataaa tcatctgtaa tcgtttcagc ttgcaaaaaa tagcgagcga
    21841 tttcttgctc taggtctgtc atttcttcaa aatgtgaatc aatgatagtt gcgatatctg
    21901 gtttgtccat agggaaagct cctttacatg ggtcatactg gaagactaga tcagggaata
    21961 gtcacacttc attataacac ataatataag gatagataaa taaaaacgca tctctgtttt
    22021 aaaaacgaaa aaatcgaaaa agcttctctc ttttccataa ttttctactc aaattgtggt
    22081 acaattaaga gtaagatttt aagttagaaa tgagactgat ttgtatgaga aaatttaaca
    22141 gccattcgat tccgattcgg cttaatttat tgttttcaat cgtcatttta ctctttatga
    22201 ccattattgg tcgtttgttg tatatgcagg ttttgaacaa ggatttttac gaaaaaaagc
    22261 tagcctcagc tagtcagacc aagattacaa gcagttcagc ccgtggggaa atttatgatg
    22321 ctagtggaaa acctttggta gaaaatacgt taaagcaggt tgtttccttt acgcgtagca
    22381 ataaaatgac ggctacagac ttaaaagaaa cagctaaaaa gttactgact tatgtgagca
    22441 tcagttctcc aaatttgaca gaacgccagc tggcggatta ctatttggct gatcctgaaa
    22501 tctataaaaa aacagtggaa gctctcccaa gtgagaaacg cttggattca gatggcaatc
    22561 gtctatccga atcagaactg tataacaatg cggtcgatag tgtccaaaca agtcaactaa
    22621 actatacaga ggatgaaaag aaagaaatct atctttttag tcagttaaat gctgttggaa
    22681 actttgcgac aggaaccatt gctacagatc ctctaaatga ttctcaggtg gctgttattg
    22741 cctctatttc aaaggagatg cctggcatta gtatttctac ttcttgggat agaaaggttt
    22801 tggaaacttc cctttcttct atagttggga gtgtatccag tgaaaaagct ggtctcccag
    22861 cggaagaagc agaagcctat cttaaaaaag gctattctct aaatgatcgt gtaggaacct
    22921 cctatttgga aaagcaatat gaagagacct tacaaggaaa acgctcggta aaagaaatcc
    22981 atctggataa atatggcaat atggaaagcg tggatacaat tgaggaaggt agtaagggaa
    23041 acaatatcaa actgaccatt gatttggctt tccaagatag cgtggatgct ttactgaaaa
    23101 gttatttcaa ttccgagcta gaaaatggtg gagccaagta ttctgaaggt gtctatgcag
    23161 tcgcccttaa cccaaaaaca ggtgcggttt tgtctatgtc agggattaaa catgacttga
    23221 aaacgggaga gttgacgcct gattccttgg gaacggtaac caatgtcttt gttccaggtt
    23281 cggttgtcaa ggcggcgacc atcagctcag gttgggaaaa tggagtcttg tcaggaaacc
    23341 agaccttgac agaccagtcc attgtcttcc aaggttcagc tcccatcaat tcttggtata
    23401 ctcaggctta cggttcattc cctatcacag cggtccaagc tctggagtat tcatcaaata
    23461 cctatatggt ccaaacagcc ttaggtctta tggggcaaac ctatcaaccc aatatgtttg
    23521 tcggcaccag caatctagag tctgctatgg agaaactgcg ttcaaccttt ggcgaatatg
    23581 gcttgggtac tgcgacagga attgacctac cagatgaatc tactggattt gttcccaaag
    23641 agtatagctt tgctaattac attactaatg cctttgggca gtttgataac tatacgccga
    23701 tgcagttggc tcagtatgta gcaactattg caaataatgg tgttcgtgtg gctcctcgta
    23761 ttgttgaagg catttatggt aataatgata agggaggact gggtgacttg attcagcaac
    23821 tgcaaccgac agagatgaat aaggtcaata tatccgactc cgatatgagc atcttgcacc
    23881 aaggttttta tcaggttgcc catggtacta gtggattgac aactggacgt gccttttcaa
    23941 atggcgcctt ggtatccatt agcggaaaaa caggtacagc cgaaagctat gtggcagatg
    24001 gtcagcaagc aaccaatacc aatgcggtgg cctatgcccc atctgataat ccccaaatcg
    24061 ctgttgcagt ggtctttcct cataatacca atctaacaaa tggtgtagga ccttccattg
    24121 cgcgtgacat tatcaatctg tatcaaaaat accatccaat gaactagaaa ggaaattatg
    24181 ctttatccaa cacctattgc caagttgatt gacagttatt ctaagttacc aggtatcggg
    24241 attaagacgg ctacgcgtct ggccttttat acgattggga tgtctgctga tgatgtcaat
    24301 gaatttgcaa aaaatctcct ttctgctaag agagaattga catattgttc tatttgtgga
    24361 cgtttgacag acgacgatcc ttgttctatc tgtactgatc cgactcgtga ccagacaaca
    24421 attttagttc ttgaggatag tagagatgtg gcagccatgg aaaatatcca agaataccat
    24481 ggactctatc atgtccttca tggcctcatt tctcctatga atggtatcag tccggacgat
    24541 atcaatctca agagccttat gactcgtctt atggatagtg aagtttcaga agtgattgtg
    24601 gcgactaatg ctacagcgga tggtgaagcg acttccatgt atctttcacg tttgctcaag
    24661 ccggctggta tcaaggttac gcgtctagca cgaggtctcg ctgtgggagc ggacattgag
    24721 tatgcggacg aagtgacact cttacgagcg attgaaaatc ggacagagtt gtaagtgtag
    24781 gcaaatttac gaactccatt catttataaa aaatcaaaga ggctgaaaat cgttcctatc
    24841 ggcctctttt tgtatagtgt gatgagtagg atcaggttca agttttaaaa aaccaagcaa
    24901 atatgatata ctaaagagcg agtattctag tagaattagg acaaataata tgaaacaaac
    24961 gattattctt ttatatggtg gacggagtgc ggaacgcgaa gtctctgtcc tttcagctga
    25021 gagtgtcatg cgtgcggtca attacgaccg tttcacagtc aagactttct ttatcagtca
    25081 gtcaggtgac tttatcaaaa cacaggaatt tagtcatgct ccggggcaag aagaccgtct
    25141 catgaccaat gaaaccattg attgggataa gaaagttgca ccaagtgcta tctacgaaga
    25201 aggtgcagtg gtctttccag tccttcacgg gccaatggga gaagatggct ctgttcaagg
    25261 attcttggaa gttttgaaaa tgccttacgt tggttgcaac attttgtcat caagtcttgc
    25321 catggataaa atcacgacta agcgtgttct ggaatctgct ggtattgccc aagttcctta
    25381 tgtggctatc gttgaaggcg atgatgtgac tgctaaaatc gctgaagtgg aagaaaaatt
    25441 ggcttatcca gtcttcacta agccgtcaaa catggggtct agtgtcggta tttctaagtc
    25501 tgaaaaccaa gaagaactcc gtcaagcctt aaaacttgcc ttccgatatg acagccgtgt
    25561 cttggttgag caaggagtga atgcccgtga aattgaggtt ggcctcttgg gtaactacga
    25621 tgtcaagagc acgctacctg gagaagttgt caaggacgtt gccttttatg actacgatgc
    25681 caagtatatt gataacaaga ttactatgga tattcctgcc aaaatcagtg atgatgtggt
    25741 ggctgtcatg cgtcaaaatg cagaaacagc cttccgtgcc attggtggcc ttggtctatc
    25801 tcgttgcgat ttcttctata cagataaggg agagattttt ctcaacgagc tcaataccat
    25861 gccaggtttt acccagtggt ctatgtaccc actactttgg gacaatatgg ggatcagcta
    25921 cccagaacta atcgagcgtt tggttgacct tgccaaggaa agttttgaca agcgcgaagc
    25981 gcatttgata taaaatgaaa gagagggtag aagccagaac catcactgca cggtgactag
    26041 agttctcgga cttcagccct ttttaaagga gtagaaatga aattaacaat ccatgaaatt
    26101 gcccaagttg ttggagccaa aaatgatatc agtatctttg aggacaccca gttagaaaaa
    26161 gctgagtttg atagtcgttt gattggaact ggagatttat ttgtgccact taaaggtgcg
    26221 cgtgatggcc atgactttat tgaaacagcc tttgaaaatg gtgcagcagt aaccttgtct
    26281 gagaaagagg tctcaaatca tccttacatt ctagtagatg atgttttgac agcctttcaa
    26341 tccctagcat cctactatct tgaaaaaacg actgttgatg tctttgctgt tacaggttca
    26401 aatggcaaga caacgactaa ggatatgttg gcgcatttac tgtcaacaag atacaagacc
    26461 tacaaaacac aaggcaatta caataatgag attggccttc cttacacagt tcttcatatg
    26521 cctgaaggaa cagaaaagtt ggttttggag atgggacagg atcacttggg agatattcat
    26581 ctcttgtctg aattggctcg tccaaaaaca gccatcgtga ccttggttgg agaagctcat
    26641 ttggcctttt tcaaagatcg ttctgagatt gctaaaggaa aaatgcaaat tgcagacgga
    26701 atggcttcag gttccttgct tttagcgccg gctgacccta tcgtagagga ctatttgcca
    26761 actgataaaa aggtggttcg ttttggtcaa ggagcagagc tgggaattac cgacttggtt
    26821 gagcgcaaag atagtctgac cttcaaggtc aatttcttag agcaagccct tgatttgcca
    26881 gtaactggca agtacaatgc gacaaatgct atgattgcat cctatgttgc cttgcaagaa
    26941 ggagtttcag aggagcaaat tcgtttggcc ttccaacatc ttgaattgac gcgtaaccgt
    27001 accgagtgga agaaagcagc caatggagca gatatcctgt cagatgttta taatgccaat
    27061 ccaactgcta tgaaactgat tttagagact ttctctgcca ttccagccaa tgaaggtggc
    27121 aagaaaattg cagtgttggc ggatatgaag gagcttggtg accagtctgt tcaacttcat
    27181 aatcagatga ttttgagcct ctccccagat gtgcttgata tcgttatttt ctatggagaa
    27241 gatattgctc agttggctca attggccagt caaatgtttc caatcggcca cgtttactac
    27301 ttcaagaaaa cagaagacca ggatcaattt gaagacctag tcaagcaggt taaggaaagc
    27361 cttggagcct atgaccaaat cttgctaaaa ggttctaact ctatgaatct agccaaattg
    27421 gtagaacgtt tagaaaatga agccaagtga ttttgtcaag tatctgcaaa gaatgattgc
    27481 ccttacagat actggcttaa cctttacaaa agatcctttt gaccgtgagc gctacgagga
    27541 cttgcgaagt ctgttatctg aaatgttgaa tcagggatca gacctggatg cagaagaagt
    27601 agcagaagtc ttgaaaccaa cttcagctta tgcgactccc ttaatggacg tccgtgcttg
    27661 gattgttgag gatgagaaga tttgtctggt taggggacaa ggagaggata gttgggcttt
    27721 gccaggtggc tttggtgaag tcggctattc tccaactgaa aatattctca aggaaattga
    27781 agaagaaacc ggttttaaag ccaaagttga aagactgcta gctgtttttg ataccaatcg
    27841 tttccaacta cagagtaaac aatatgcaaa gtttgttttt gaatgtaagt ttctcgatgg
    27901 acaattccaa gaaaatcaag aaattgcaga ccttcaattt tttgccattg atcaactgcc
    27961 agccttatct gaaaaacgca ttaccaagga gcaaatcgag attctttggc aggtttatca
    28021 aggtcagagg gagcaatatc ttgactaaga agatgattat cgtattttta aatccatttt
    28081 taacaactag catggtataa taatatgcag gaaaattttg aattatgagg aagactagat
    28141 gaatttatgg gatattttct ttacgactca ggcaaccgag ccgcccaaat ttgacctttt
    28201 ttggtatgtt agcctattta cgctcttagc cttaaccttt tatacagccc atcgctatcg
    28261 tgaaaagaag gtttaccaac gatttttcca aatcttgcag actgttcagt taatccttct
    28321 ttatggttgg tactgggtca atcatatgcc actgtcagaa agcctaccct tttaccattg
    28381 ccgtatggct atgtttgtgg tactcttgct tcctggtcag tccaaatata aacaatactt
    28441 tgcattattg ggaacatttg ggacattagc agcctttgtt tatccagtgc cagatgctta
    28501 cccttttcca catatcacca ttctatcctt tatctttggt catttagcac tcttggggaa
    28561 ctctctagtt tatctattga gacagtataa tgcgcgattg ctggatgtga agggaatttt
    28621 tctcatgacc tttgccctaa atgccttgat ttttgtggtc aatttggtga caggtggcga
    28681 ttacggattt ttgacaaaac cgccattggt tggggatcac ggtctagtag ctaattattt
    28741 acttgtttca attgtgctgg tagctactat cagtttgact aagaaaatct tagaattctt
    28801 tttagctcaa gaagcagaaa aaatgattgc aaaggaagct taacacagag ctttcttttt
    28861 tgctcttaga gagtttttac aagcagctta taaaataaga atttctgaat agacaaactc
    28921 aaaaaatggc tgggaaattt aggaaaaaag caagcacgat taaatttttt gtgttataat
    28981 attttgtgaa tagctatgcc tatgtttagc tatggaataa tacgaagtgc gaaacttgga
    29041 agatagagag gaagcgatgt aatggctaga gaaggctttt ttacaggtct agatattgga
    29101 acaagctctg tcaaggtgct tgtggccgag cagagaaatg gtgaattaaa tgtaattggc
    29161 gtgagtaatg ccaaaagtaa aggtgtaaag gatggaatta ttgttgatat tgatgcagca
    29221 gcaactgcta tcaagtcagc catttcccaa gcggaagaaa aggcaggcat ttcgattaaa
    29281 tcagtgaatg tcggcttgcc tggtaatctt ttgcaggtag aaccaactca ggggatgatt
    29341 ccagtaacat ctgatactaa ggaaattacg gatcaagatg ttgaaaatgt tgtcaaatca
    29401 gctttgacaa agagtatgac acctgaccgt gaagtcatta cctttattcc tgaagaattt
    29461 attgtggatg gtttccaagg gattcgtgac ccacgtggta tgatgggggt tcgccttgaa
    29521 atgcgtggtt tgctttatac aggacctcgt actatcttgc acaatttgcg taagacggtt
    29581 gagcgtgcag gtgttcaggt tgaaaatgtt atcatttcac cactagcaat ggttcagtct
    29641 gttttgaacg aaggggaacg tgaatttggt gctacagtga ttgatatggg ggcaggtcaa
    29701 acgactgtcg ctacaatccg taatcaagaa ctccagttca cacatattct ccaagaaggt
    29761 ggagattatg taactaaaga tatctccaag gttttgaaaa cctctcgcaa attagcggaa
    29821 ggcttgaaac tgaattacgg ggaagcctat ccgcctcttg caagcaaaga aaccttccaa
    29881 gtagaggtta ttggagaagt ggaagcagtc gaagtgacgg aagcctactt gtcagaaatt
    29941 atttctgcac gaatcaagca catccttgaa caaatcaagc aagaattaga tagaaggcgt
    30001 ctattggacc tccctggtgg tattgtctta atcggtggga atgccatttt accaggtatg
    30061 gttgagcttg ctcaggaagt ctttggcgtc cgtgtcaagc tttatgttcc aaatcaagtt
    30121 ggtatccgta atccagcctt tgcgcatgtg attagtttat cagaatttgc gggtcaatta
    30181 acagaagtta atcttttggc tcagggagcg ataaaaggtg agaatgactt aagtcatcag
    30241 ccaattagtt ttggtgggat gctgcaaaaa acagctcagt ttgtacaatc aacgcctgtt
    30301 caaccagctc ctgctccaga agtagagccg gtggcgccta cagaaccaat ggcggatttc
    30361 caacaagctt cacaaaataa accgaaatta gcagatcgtt tccgtggctt gatcggaagc
    30421 atgtttgacg aataaagagg aaaaataaat tatgacattt tcatttgata cagctgctgc
    30481 tcaaggggca gtgattaaag taattggtgt cggtggaggt ggtggcaatg ccatcaaccg
    30541 tatggtcgac gaaggtgtta caggcgtaga atttatcgca gcaaacacag atgtacaagc
    30601 attgagtagt acaaaagctg agactgttat tcagttggga cctaaattga ctcgtggttt
    30661 gggtgcagga ggtcaacctg aggttggtcg taaagccgct gaagaaagcg aagaaacact
    30721 gacggaagct attagtggtg ccgatatggt cttcatcact gctggtatgg gaggaggctc
    30781 tggaactgga gctgctcctg ttattgctcg tatcgccaaa gatttaggtg cgcttacagt
    30841 tggtgttgta acacgtccct ttggttttga aggaagtaag cgtggacaat ttgctgtaga
    30901 aggaatcaat caacttcgtg agcatgtaga cactctattg attatctcaa acaacaattt
    30961 gcttgaaatt gttgataaga aaacaccgct tttggaggct cttagcgaag cggataacgt
    31021 tcttcgtcaa ggtgttcaag ggattaccga tttgattacc aatccaggat tgattaacct
    31081 tgactttgcc gatgtgaaaa cggtaatggc aaacaaaggg aatgctctta tgggtattgg
    31141 tatcggtagt ggagaagaac gtgtggtaga agcggcacgt aaggcaatct attcaccact
    31201 tcttgaaaca actattgacg gtgctgagga tgttatcgtc aacgttactg gtggtcttga
    31261 cttaaccttg attgaggcag aagaggcttc acaaattgtg aaccaggcag caggtcaagg
    31321 agtgaacatc tggctcggta cttcaattga tgaaagtatg cgtgatgaaa ttcgtgtaac
    31381 agttgtcgca acgggtgttc gtcaagaccg cgtagaaaag gttgtggctc cacaagctag
    31441 aactgctact aactaccgtg agacagtgaa accagctcat tcacatggct ttgatcgtca
    31501 ttttgatatg gcagaaacag ttgaattgcc aaaacaaaat ccacgtcgtt tggaaccaac
    31561 tcaggcatct gcttttggtg attgggatct tcgccgtgaa tcgattgttc gtacaacaga
    31621 ttcagtcgtt tctccagtcg agcgctttga agccccaatt tcacaagatg aagatgaatt
    31681 ggatacacct ccatttttca aaaatcgtta agtaaatgaa tgtaaaagaa aatacagaac
    31741 ttgtttttcg agaagttgca gaggctagtc tgagtgctca tcgagagagt ggttcggtct
    31801 ctgtcattgc agttaccaag tatgtagatg taccgacagc ggaagccttg cttccgctag
    31861 gtgttcatca tatcggtgaa aatcgtgtag ataagtttct ggaaaaatat gaagctttaa
    31921 aagatcgaga tgtgacttgg catttgattg gtaccttgca aagacgtaag gtgaaagata
    31981 tcattcaata cgttgattat ttccatgcat tggactcagt aaagctagca ggggaaattc
    32041 aaaaaagaag tgaccgagtc atcaagtgtt tccttcaagt aaatatttct aaagaagaaa
    32101 gcaaacacgg tttttcgaga gaggaactgc tggaaatctt gccagagtta gccagactag
    32161 ataagattga atatgttggt ttaatgacga tggcaccttt tgaggctagc agtgagcagt
    32221 tgaaagagat tttcaaggcg acccaagatt tacaaagaga aattcaagag aaacaaattc
    32281 caaatatgcc tatgaccgag ttaagtatgg gaatgagtcg tgattataaa gaagcgattc
    32341 aattcggttc cacttttgtt cgtataggta catcattttt taagtaggag agaaccatgt
    32401 ctttaaaaga tagattcgat agatttatag attattttac ggaggatgag gattcaagtc
    32461 tcccttatga aaaaagagat gagcctgtgt ttactccagt aaattcttca caggaaccgg
    32521 ctctcccaat gaatcaacct tcacagtcgg ctggtacaaa agagaacaat atcaccagac
    32581 ttcatgcaag acaacaggaa ttggcaaatc agagtcagcg tgcaacggat aaggtcatta
    32641 tagatgttcg ttatcctaga aaatatgagg atgcaacaga aattgttgat ttattggcag
    32701 gaaacgaaag tatcttgatt gattttcagt atatgacaga ggtgcaggct cgtcgttgtt
    32761 tggactattt ggatggagct tgtcatgttt tagctggaaa tttgaaaaag gtagcttcta
    32821 ccatgtattt gttgacacca gtgaatgtta ttgtaaatgt tgaagatatc cgtttaccag
    32881 atgaagatca acagggtgag ttcggttttg atatgaagcg aaatagagta cgataatgat
    32941 ttttttaatt cgtatgattt ataatgcagt ggatatttac tccctgattt tggtagcctt
    33001 cgctgtcatg tcttggtttc caggtgccta cgaatccagt ttaggtcgtt ggattgtagc
    33061 gttggtgaaa ccagtgcttg ctcccttgca acgcctgcct ttacagatag cgggtcttga
    33121 tttatctgtt tgggtcgcga ttgttttggt tcgattttta ggagaaaacc tagtgcgttt
    33181 tctggcgatg ataggatgaa taaagggatt tatcagcatt tctccataga agatcgtcca
    33241 tttcttgaca agggaatgga atggataaag aaggtagaag atagctatgc tcctttttta
    33301 actcctttta tcaatcctca tcaggagaag ctattaaaga ttttggccaa aacctatggt
    33361 cttgcttgta gcagtagtgg ggaattcgtc tcgagtgagt atgttcgagt tttattatac
    33421 ccagattatt tccaaccaga gttttcagat tttgaaatat ctctccagga aattgtgtat
    33481 tccaataaat ttgaacattt aacgcatgct aagattttag ggacagtcat caatcaatta
    33541 gggattgaac ggaaactttt tggagatatc ctagtagatg aagaacgggc gcagattatg
    33601 attaatcagc agtttcttct tctctttcaa gatggactaa agaaaattgg tcgtatacct
    33661 gtttcgctgg aggaacgtcc tttcaccgag aaaatagata agctagaaca gtatcgagaa
    33721 ctggatttat ctgtgtctag ttttcgatta gatgttcttt tatcaaatgt tttgaaacta
    33781 tctaggaatc aagcaaacca gttgattgaa aagaaacttg tccaagtaaa ttatcatgtg
    33841 gtagacaaat cagattacac tgttcaagtt ggagacttga ttagtgtgag aaaatttggt
    33901 cgcttgagat tacttcaaga taagggacaa acgaaaaaag agaagaaaaa aataaccgtc
    33961 cagttattat taagtaagtg aggaatagaa tgccaattac atcattagaa ataaaggaca
    34021 agacttttgg aactcgattc agaggttttg atccagaaga agtcgatgaa tttttagata
    34081 ttgtggttcg tgattacgaa gatcttgtgc gtgcgaatca tgataaaaat ttgcgtatta
    34141 agagtttaga agagcgtttg tcttactttg atgaaataaa agattcattg agccagtctg
    34201 tattgattgc tcaggataca gctgagagag tgaaacaggc ggcgcatgaa cgttcaaaca
    34261 atatcattca tcaagcagag caagatgcgc aacgcttgtt ggaagaagct aaatataagg
    34321 caaacgagat tcttcgtcaa gcaactgata atgctaagaa agtcgctgtt gaaacagaag
    34381 aattgaagaa caagagccgt gtcttccacc aacgtctcaa atctacaatt gagagtcagt
    34441 tggctattgt tgaatcttca gattgggaag atattctccg tccaacagct acttatcttc
    34501 aaaccagtga tgaagccttt aaagaagtgg ttagcgaagt acttggagaa ccgattccag
    34561 ctccaattga agaagaacca attgatatga cacgtcagtt ctctcaagca gaaatggaag
    34621 aattacaagc tcgtattgag gtagccgata aagaattgtc tgaatttgaa gctcagatta
    34681 aacaggaagt ggaaactcca actcctgtag tgagtcctca agttgaagaa gagcctctgc
    34741 tcatccagtt ggcccaatgt atgaagaacc agaagtagct ccagtgcatc cgacaggtcc
    34801 aacaccagct acagaaactg ttgattcagc accaggattt gaagcaccgc aagaatccgt
    34861 tacaatttta taagaaacga tgtgagaaca atatcttatc cttatatttc cagcgagcag
    34921 gagatggtgt gagtcctgca ttccctaacg ataagattat cctctcaaaa actcaagtct
    34981 gaatctagta agatttgacg tttcccacgt tacgggataa gagggagaaa gactaaatct
    35041 ttttccgaat aaaggtggta ccacgatttt cgtccttttt ggaagtcgtg gtttttaatt
    35101 tgttattatt tataaaggag ataccatgaa actaaaagat acccttaatc ttgggaaaac
    35161 agctttccca atgcgtgcag gccttccgac caaagagcca gtttggcaaa aggaatggga
    35221 agatgcaaaa ctttaccaac gtcgtcaaga actaaatgaa gggaaaccgc attttgtctt
    35281 gcatgatggc cctccatacg caaacggaaa tatccacgtt ggacatgcca tgaatcatat
    35341 ctcaaaagat atcatcattc gttctaagtc tatgtcaggt tttaacgcac cttatatccc
    35401 aggttgggat actcatggtc tgccaatcga gcaagttttg gcaaagcaag gtgtgaagcg
    35461 caaagaaatg gacttggttg agtacttgaa actttgccgt gaatacgctc tttctcaagt
    35521 ttataaacaa cgtgatgatt tcaagcgctt ggggatgtca ggtgactggg aaaatttata
    35581 tgtgacttta actccagact acgaagcagc ccaaatccgt gtatttggtg agatggctaa
    35641 taagggttat atctaccgtg gtgctaagcc agtttactgg tcttggtcat ctgagtcagc
    35701 ccttgccgaa gcggaaattg aataccatga tttggtttca acttcccttt actatgccaa
    35761 taaggtaaaa gatggcaaag gtgttctaga tacagatact tatatcgttg tttggacaac
    35821 tactccattt actatcacag cttctcgtgg tttgactgtt ggtgcagata ttgattacgt
    35881 tttggttcaa cctgctggtg aaactcgtaa gtttgtcgtt gctgcagaat tgttgactag
    35941 cttgtctgag aaatttggct gggttgatgt tcaagttttg gcaacttacc gtggtcaaga
    36001 actcaaccac atcgtaacag aacatccatg ggatacagct gtagatgaat tggttatcct
    36061 tggtgaccac gttacaactg actctggtac aggtattgtc catacagccc ctggttttgg
    36121 tgaggacgat tacaatgttg gtattgctaa taatcttgaa gtcgcagtga ctgttgatga
    36181 acgtggtatc atgatgaaga atgctggtcc tgaatttgaa ggtcaattct atgaaaaggt
    36241 agttccaact gttattgaaa aacttggtaa cctccttctt gcccaagaag aaatctctca
    36301 ctcatatcca tttgactggc gtaccaagaa accaattatc tggcgtgcag taccacagtg
    36361 gttcgcctct gtttcaaaat tccgccaaga aatcttggat gctattgata aagttaaatt
    36421 ccatacagaa tggggtaaag tacgtctata taatatgatt cgtgaccgtg gtgactgggt
    36481 tatctctcgt caacgtgctt ggggtgttcc acttccaatc ttctatgcag aagacggtac
    36541 agctatcatg acagctgaga ctatcgaata tgtggctcaa ctctttgaag tacatggttc
    36601 aagcatttgg tgggaacgtg atgccaaaga cctcttgcca gaaggattta cacatccagg
    36661 ttctccaaat ggcgagttca aaaaagaaac tgatatcatg gacgtttggt ttgactcagg
    36721 ttcatcatgg aatggtgttt tggtaaatcg tccaaatctg acttatccag ctgaccttta
    36781 ccttgaaggt tctgaccaat accgtggttg gttcaactca tcactcatta catctgttgc
    36841 caaccatggc gtagcacctt acaaacaaat cttgtcacaa ggttttaccc ttgacggtaa
    36901 aggtgagaag atgtctaaat ctcttggaaa taccattgct ccaagcgatg ttgaaaaaca
    36961 atttggtgct gaaatcttgc gtctctgggt aacaagtgtt gactcaagca atgacgtgcg
    37021 tatctctatg gatatcttga gccaagtctc tgaaacttac cgtaagattc gtaatactct
    37081 tcgtttcttg attgccaata catctgactt taacccaact caagatgcag tcgcttacga
    37141 tgaacttcgt tcagttgata agtacatgac cattcgcttt aaccagcttg tcaagaccat
    37201 tcgtgatgcc tatgcaaact ttgaattctt gacaatctac aaggccttgg tgaactttat
    37261 caacgttgat ttatcagcct tttaccttga ttttgctaaa gatgttgttt acatcgaagg
    37321 tgctaaatca ctggaacgtc gtcaaatgca gactgtcttc tatgatattc ttgtcaaaat
    37381 caccaaactc ttgacaccaa tccttcctca cactgcggaa gaaatctggt catatcttga
    37441 gtttgaaaca gaagacttcg tccaattgtc agaattacca gaagttcaaa cttttgctaa
    37501 ccaagaagaa atcttggata catgggcagc cttcatggac tttcgtggac aagcacaaaa
    37561 agccttggaa gaagctcgta atgcaaaagt tatcggtaaa tcacttgaag cacacttgac
    37621 agtttatcca aatgaagtgg tgaaaactct actcgaagca gtaaatagca atgtggctca
    37681 acttttgatc gtgtctgagt tgaccatcgc agaaggacca gctccggaag ctgcccttag
    37741 cttcgaagat gtagccttca cagttgaacg tgctgctggt gaagtatgtg accgttgccg
    37801 tcgtattgac ccaacaacag cagaacgtag ctaccaggca gttatctgtg accactgtgc
    37861 aagcatcgta gaagaaaact ttgcggaagc agtcgcagaa ggatttgaag agaaataaga
    37921 ttgaaaagtc taggcaaaat tcaatttgag aagaaaagac aactaatttt atagtctatt
    37981 aaacgcattg tatcacgttt ttgaacacct gatatgatgc gttttttatt tattttaaaa
    38041 atttgcgagg tatgactttt tatactcaac aagaatcaaa gagaaactta gcaagctaac
    38101 agtagtaaga taaaatagga atttgatatt agggataaga ttggtaaata gtgtaatatt
    38161 tttacaagaa taaatttata tagttatttc tggtttctga aaagtattat attatatttt
    38221 atttcatatt atacaaattt ttattttata atatcagaaa atactttttt tttaaaaagc
    38281 aaatatgata caattttatt tgaaaaaaaa taaaaaagga gattttatta tgaaatcaag
    38341 tggtatcgtc ggtcttgtgg gaggaatttt acttcttatt tgtccttttg tcttgttggg
    38401 aacagcggta aacacagctg ctacaactct taatggagga gctactgcag gggctttttc
    38461 aggtgttgcc ttactcttga atgccttgaa gattgcaaat cttgttcttg gtatcattgc
    38521 tattgtttac tataaaggag ataagcgtgt aggtgcagct ccgtctgtac taatgattgt
    38581 ttctggtgaa gttagtctca ttccattctt aggatgggtt ggggggattc ttgctattat
    38641 cggaggatct ctattccttg caacattgaa gaaattcaaa tcagaagaat aaaaggtatt
    38701 ttagcatgaa aagaacaaaa aagtttatcg gtataggagt agctctatta tctctttctc
    38761 ttctagttgc atgtggaaca taaagttcaa agaatacttc aacaagtaat gatgagaaga
    38821 cagtagcaac atccaatagt tcaaaagaaa caatcacttt cgatacaccg gttgtaacag
    38881 acgatgcgat tgaatcaata cgcacttatg cagattatat agatctttat aaaaatattt
    38941 ttgatgatta ttttactaaa actgaggaag gtttcaaagg cacagctatg gaaaataatg
    39001 actcgtttac taaactaaaa gagtcaactc aaaaattatt cgatgcgcag aaaaaaaggt
    39061 taaataatga agatagaata gaaacaacca aaaacaatgt gattgccaaa cattgtcaaa
    39121 cagtcctttc ctttttggtt ttgactagct tttttgtgaa aaattgtgta aaatagaata
    39181 gataaacgag gggaaacctc ggaaaattta aaggagaatc catctaatgg taaaattggt
    39241 ttttgctcgc cacggtgagt ctgaatggaa caaagctaac cttttcactg gttgggctga
    39301 tgttgatttg tctgaaaaag gtacacaaca agcgattgac gctggtaaat tgatcaaaga
    39361 agctggtatc aaatttgacc aagcttacac ttcagtattg aaacgtgcta tcaaaacaac
    39421 taacttggct cttgaagctt ctgaccaatt gtgggttcca gttgaaaaat catggcgctt
    39481 gaacgaacgt cactacggtg gtttgactgg taaaaataaa gctgaagctg ctgaacaatt
    39541 tggtgatgag caagttcaca tctggcgtcg ttcatacgat gtattgcctc caaacatgga
    39601 ccgtgatgat gagcactcag ctcacacaga ccgtcgttac gcttcacttg acgactcagt
    39661 tatcccagat gctgaaaact tgaaagtgac tttggaacgt gctcttccat tctgggaaga
    39721 taaaatcgct ccagctctta aagatggtaa aaacgtattc gtaggagctc acggtaactc
    39781 aatccgtgcc cttgtaaaac acatcaaagg tttgtcagat gacgagatca tggacgtgga
    39841 aatccctaac ttcccaccat tggtattcga attcgacgaa aaattgaacg tcgtttctga
    39901 atactacctt ggaaaataaa aaattgtaag tctagaattg atttctaggc tttttatgtt
    39961 agtatggaag tatgataagg aataaaaaac aagattatgt actggcctac aagcaaccag
    40021 cttcaaccac ttacatgggt tgggaagaag aagctttacc gataggcaat ggttctttag
    40081 gagcaaaagt atttggcctt ataggggctg aacggattca atttaatgaa aaaagtctct
    40141 ggtctggagg tccacttcct gatagttcag attatcaggg tggaaatctt caggatcagt
    40201 atgtttttta gctgagattc ggcaggcttt ggagaagaga gattacaatc tggctaagga
    40261 actggctgag cagcacctaa ttgggccaaa aacgagtcaa tatgggacct atctgtcttt
    40321 tggggatatt cacattgagt tcagccagca aggtacgact ttgtctcagg tgacggacta
    40381 tcagagacag ctgaatatta gtaaggcact tgcgacgact tcttatgtct ataagggaac
    40441 gcgatttgaa cgtgaagctt ttgcgagttt tccagatgat ctcttggttc aatgttttac
    40501 taaggaaggg ttggaaactc tagattttac tatagaacta tccttgacct gtgatttggc
    40561 ttctaatgga aagtatgaac aggaaaagtc tgattacaag gagtgtaagt tggatattac
    40621 tgattctcat atcttgatga agggaagagt taaggataat gatctgcggt ttgctagtta
    40681 tctagcttgg gaaacggatg gagatattag agtttggtca tatagggttc agatatcagg
    40741 agccagttat gccaatctct tcttggccgc taagacggat tttgcccaaa atcctgctag
    40801 caattatcgc aagaaactag atttagagca acaggtgaga gacttggtgg acacagctaa
    40861 agaaaagggc tatacccaat tgaaatcaag gcatatcgag gactaccaag ccttattcca
    40921 gcgtgttcaa ttggatttgg aagctgatgt tgacgcatcc actacagatg atttgttaaa
    40981 aaattataag ccacaagaag ggcaggcttt ggaggagctg ttcttccagt atggacggta
    41041 tttattgatt agttcgtcca gagactgccc agatgctcta ccagctaacc tacagggagt
    41101 ctggaatgcg gtcgacaatc ctccttggaa ttcggactat cacttaaatg tcaatctgca
    41161 gatgaattat tggccagcct atgttaccaa tctcctagag gcggtctttc cggtcatcaa
    41221 ctatgtagat gatttgcgtg tctatggtcg tctagcggct gtaaagtatg caggaatcgt
    41281 ctctcaaaaa ggtgaggaaa atggttggtt ggttcatact caagcgactc cctttggttg
    41341 gacggcacct ggttgggatt actattgggg ttggtcacca gctgccaatg cgtggatgat
    41401 gcaaaccgtt tatgaagcct attcatttta tagggaccaa gactatctca gagagaaaat
    41461 ttatcccatg ttgagggaaa cggttcgttt ttggaatgcc tttttacata aggatcagca
    41521 ggcgcagcgt tgggtgtctt ctccgtctta ttccccagaa catgggccga tttcgattgg
    41581 caatacttat gaccaatctc taatttggca gttatttcat gattttattc aggctgctca
    41641 ggaattggga ctggatgagg acttgttgac tgaggttaag gagaagtctg atttactaaa
    41701 tcctttgcaa atcactcaat ctggtcgaat cagggagtgg tatgaggagg aagagcagta
    41761 ttttcaaaat gagaaagtgg aggcccagca tcggcacgct tcccatctag tgggactcta
    41821 tcctggcaat ctctttagct acaagggaca agagtatatt gaagcggcgc gtgctagcct
    41881 caatgatcgt ggagatggcg gcacaggctg gtccaaggct aataagatca atctctgggc
    41941 gcgtttggga gatggcaatc gagcccataa attattggca gagcagttaa agacatccac
    42001 cttgccaaat ctttggtgta gccatcctcc ttttcagata gatggtaatt ttggtgctac
    42061 tagtggcatg gcagaaatgt tactccagtc tcatgcagct tatctggtac ctctagctgc
    42121 cctacctgat gcttggtcaa caggttctgt ttcaggctta atggcacgtg gacattttga
    42181 agtgagcatg agctgggaag ataaaaaact cttacagttg accattttat caaggagtgg
    42241 aggagatttg cgagtttctt atccagatat tgagaagagt gtgattaaaa tgaatcaaga
    42301 aaaaataaaa gcgaaatgca tggggaaaga ttgtatttcg gtggcaacag cagaaggtga
    42361 tcttgttcaa ttttattttt aagaagatgt tataaggcag taatttgaaa ctgcctttta
    42421 ataaggattt aagaatataa gcagttttca actagttgaa aaagcgttat aatgataata
    42481 ggaagtaata ctcaatgaaa atcaaagagc acaaacaagg aagctagccg caggttgctc
    42541 aaaacagtgt tttgaggttg cagatggaag ctgacgtggt ttgaagagag attttcgagg
    42601 agtataattt gtttgataga gggtgggtct gatggcttat attgagatga aacactgtta
    42661 caagcgttat caggttgggg acacggagat tgtggccaat cgtgatgtga attttgagat
    42721 tgaaaagggg gagctggtta ttatccttgg tgcttcaggt gcaggcaagt caacagtgct
    42781 taaccttctt gggggaatgg ataccaatga tgaaggggaa atctggattg atggtgttaa
    42841 tattgcggat tatagttccc accagcgcac caattaccgt agaaatgatg tggggtttgt
    42901 ttttcagttt tataatctag tttctaatct gacagctaag gaaaatgtgg aactggcttc
    42961 tgaaattgtg acagatgtct tgaatcctga tcaggtcttg acagatgtag gtctggctca
    43021 tcgtctaaat aactttccag cccagctttc tggaggggag caacagcgag tctccattgc
    43081 acgcgcggta gccaaaaatc ctaaaattct tctttgtgat gaacctactg gagccttgga
    43141 ttatcagacg ggcaagcagg ttttgaaaat tctccaagat atgtctcgtc aaaagggagc
    43201 gacggtgatc atcgtgactc ataatggagc tttggcgccc attgctgatc gcgtgattca
    43261 tatgcacgat gccagtgtca aggatgtggt gctcaaccag catcctcagg atattgacag
    43321 tttggagtac tagtatgatc aagcgaaaaa cttattggaa ggacttaatt cagtccttca
    43381 caggctccaa ggggcgtttt ttatccatct tgatcctgat gatgttggga tctctagcct
    43441 tagtaggcct caaagtaacc agtcccaaca tggaggcgac agctaatgct tatttaacaa
    43501 ctgctcaaac cttggatttg gcagtcatgt ctaactatgg cttggatcaa gcagaccaag
    43561 aagaactaaa acagacggag ggcgcagagg tcgagtttgg ctatttgaca gatgtgacta
    43621 tggataatgg gcaggatgcc attcggctgt actccaaacc agagcgaatt tcaacctttc
    43681 agctaagaaa gggacgactt cctcagtcag acaaggaaat cgctttggcc actcatttgc
    43741 aaggccaatg cagcgtggga caggagatta gttttaaaga aaaagaagag ggtcattcct
    43801 ctttaaaaga ccatacttat accattactg gttttgtgga ttcggctgaa atcctctccc
    43861 agcgagatat gggctacgca ggaagtggaa gtgggactct gacagcctat ggggtgattt
    43921 tacctagtca gtttgatcag aaagtctaca atatagctcg tttgaaatat caagatttag
    43981 caggtttaaa tgccttttca tcagcttatg aagaaaaatc caagcaacat caggaagacc
    44041 ttgaacaaac tttatcagat aatggcaagg tacgtctgca acttttgaaa aaagaaggac
    44101 aagagtctct agacaagggg caagagaccc ttgacaaggc tcagactaat ttgcaggaag
    44161 gcaagcgtcg tttagcagct gctcaagctc gtatacaggc tcaagaaagt caactagcct
    44221 tgtttcctca agttcagaga gagcaggcta gtgctcaact tacccaagcc aagcaggaat
    44281 tgggcaagga agaagacaaa ctaaagcaag ctgaacaaaa tctagcccaa gaaaaggaaa
    44341 aattagaaaa acatcagcaa gtcttggacg atttggcgga gccaaggtat caggtctata
    44401 atcgtcagac catgccaggt ggtcagggct atcttatgta tagcaatgct tcatccagta
    44461 ttcgagcagt gggcaatatc tttcctgtgg tactttatgc cgtagcagcc atggtgacct
    44521 ttacgaccat gactcgcttt gtagacgaag agcgaactca tgcagggatt tttaaggcct
    44581 tgggttaccg tagtaaggat attatcgcca agtttctcct ttatggacta gtagctggga
    44641 ctgtcggaac ggctctaggt agtatacttg gtcattattt gctagccagt gtaatttcaa
    44701 gtgtcattac aaaaggcatg gtggtgggag aaacccagat tcagttctat tggacctata
    44761 gcttactagc tcttgtcttg agctggttgg cgagtgtgtt accagcctat ctggtggctt
    44821 ggagggaact tcatgccgaa gcagcccagc ttctacttcc taaacctcct gtcaaaggag
    44881 ctaaaatctt attggagcgt atcggtttta tctggcgtcg tctcagtttt actcataagg
    44941 taacagcccg caacatcttt cgttataagc agagaatgtt gatgacaatc tttggtgtgg
    45001 caggttctgt agctctgctc tttgcaggtt tgggaatcca atcttctgta gcaggagttc
    45061 cgtctaaaca gtttcaacaa atccaacagt atcagatgct tgtctctgaa aatcctagtg
    45121 cgaccgatca ggacaaggta gagctagcag aagtgttgaa agggcaggag atactagcct
    45181 accagaaaat ctattctaaa acgctagaca aggatttcaa aggcaaggct ggtcttcaaa
    45241 acattactct tatgatgata gagaaggaag atttgactcc ctttatccat cttcaacatc
    45301 atcagcagga gctgacatta aaagatggca tcgttattac agctaaactc gcccagctgg
    45361 caggtgtcaa ggttgggcag actttagaaa ttgaaggtaa ggaactaaag gtcgctgcta
    45421 ttactgagaa ctacgttggt cactttattt atatgagtca ggctagctat gagcaacttt
    45481 acggacagct accccaagcc aacacttatc tggtctcatt aagggatacc agtgcaacta
    45541 gtatcgaaag tcaggcgggc ttgcttatga gtcaatctgc ggtgtccagc gttgtccaaa
    45601 atgcttcagc cattcgactc ttcgactctg tcgctagctc actcaatcag accatgacca
    45661 tcttggtcat cgtatcggtt ctattagcta ttgtcatcct ttacaatctg accaatatca
    45721 acgtagctga gagaatccgt gaactctcca ctaccaaggt tcttggtttt cataataatg
    45781 aagtcaccct ctacatttac cgtgagacga ttgtgctatc ccttgtggga atcgtacttg
    45841 gtctggtagc tggtttctat ttacaccaat ttttgattca aatgatttcg cctgcgacta
    45901 ttctctttta tccgcaggta ggctgggaag tctatgtaat cccagtggca gcagtaagca
    45961 tcattttgac cttgcttggt ttcttcgtca attattatct gagaaaggtt gatatgttag
    46021 aagccctgaa atctgtagag taaggtagtt atttttagct gattgaactt ctatttacta
    46081 atattcaaaa atcctccgtt tcaaagagca gggaactctt tgtgacagag gattttttct
    46141 atagggcttt agcagctgca attgcggctt cgaagtttgg ctcagaattg atattatcca
    46201 cgtattcaac gtagcgaatc gtattgtcag tatcgaggac aaagactgcg cgtgctaata
    46261 ggtgccattc gttgatcaag agggcataat cgcgcccgaa agaatggtca aagtagtctg
    46321 aaagcataat ggcattgtca aggccttcag caccgcacca acgtttttga gcaaaaggta
    46381 ggtccattga aacagtcaat acgaccgtgt tgtccagtcc agccaattct tcattaaaac
    46441 gacgtgtttg agttgagcag atgcctgtat cgatagaagg aacgacactc aagacttttt
    46501 tcttgccatc aaaatcagcc agagattttt tagaaagatc tgttgtagta agagaaaaat
    46561 caagcgcctt gtcgccgact tgtagttgtt tacctgtaaa gctcacagga tttccgagaa
    46621 aagttaccat aggatactcc aatctttttt cttccattgt atctgaaaca gtcagaattt
    46681 tccaatgatt tgaccggaaa tgtgggcata gaaaaaacgc cagctcacat gagaatgacg
    46741 tttttcagag gcttattttg ccaatccttc agcaatcttg tcaaggttgt atttcatcat
    46801 gctgtagtag ctgtcgcctt ctttaccttg ttctgcgata gagtcagtaa agatttgtgc
    46861 gtagattggg atgtttgtgt cttgagaaac agttttcatt ggacggtcat ccacacttga
    46921 ttctacaaag agtgatggaa cttttgtttg gcgaagtttt tcaaccaagg tcttgatttg
    46981 ttcaggagtt ccttcttctt cagtattgat ttcccagatg taggcacttg ggacaccata
    47041 ggctttagag aagtatttga atgctccttc gctggttaca atgagtttct tttcagcagg
    47101 gatcttatta aatttatcct tactttcttt atcaagtttg tctaacttat cagtatattc
    47161 tttgagattt ttttcataga attctttatt gttagggtct ttggcgctca attgtttggc
    47221 gatattttta gcaaaaataa taccgttttc aaggttaagc caagcgtgtg ggtcttcttt
    47281 tcctttttca ttttgacctt caaggtagat aacatcaacg ccgtcgctga ctgcgaagta
    47341 gtctttgttt tcagttttct tggcattttc taccaatttt gtaaaccaag cattgccacc
    47401 tgtttcaagg ttgataccgt tatagaaaat caaatcagcc tcagaagttt tcttaacgtc
    47461 ttcaggaagt ggttcgtatt cgtgtgggtc ttgcccaatc ggaacgatac tatgaaggtc
    47521 aattttgtca ccagcaatat ttttagtaat atcagcgatg attgagtttg tagcaacaac
    47581 ttttagtttt tgaccagaag ttgtatcttt ttttccgcta gcacatgcta caagaatgat
    47641 tgcagaaaga aagagaacga gtaatgtacc taattttttc attagatcct ccaatttatt
    47701 agggctttgc cccttatttt aacaaatgtt tatttttcag tttcaaatat cgttgtttgg
    47761 gagcgataaa gaagctaatg agaaagaaac tagcagctgt aagcacgata ctagaacctg
    47821 ccgcaacatt aaaactatag ccaataaaga gtcccaaaac tgaagcagta gctccgaagg
    47881 ttgaggaaag gaaaatcatg cttttcagac tattagcata cagataagca gttgcagctg
    47941 gggtaatcag catggctaca atcaggatag ttccgacact ttgcatggct gtcacagaca
    48001 cgagagtcag gagtaccatg agaaggtagt gatagaaatt gacaggcatt cccatggctt
    48061 tagccaagag ttcatcaaag gaagttatca agagttgctt gaagaaaatc cagattaaca
    48121 agaggatggc tgcccccaca cccatagtaa taaacatatc cgtatcttgg acggccagga
    48181 tattaccaaa aaggatatgg aaaaggtcag ttgaactttt agcgacacca atcaagatga
    48241 taccgagggc taagaaagaa gaaaaggtaa tgccgatggc ggtatcgctt ttgataatcg
    48301 agtttccttt gatgtaggta atgatgatgg cagctagcaa tccaaagaca atggctccga
    48361 taaagaagtc aaggcccaag atgaaggaga gggctacacc tggtaagaca gcatgtgaaa
    48421 tggcatctcc catgagtgac atcccgcgta gaataatgaa acatcccacg gctccagcta
    48481 caatcccgac gacaatagct gttatcaagg cattttgtag gaaatggaat ttttgcaatc
    48541 catcgataaa ttctgcaatc ataggtcacc tccattgaaa aagagttgat taccgtaagc
    48601 ttcttttaga ttggtttcgg taaaagtttc ttttgttgga ccaaaggcaa tcacttctcg
    48661 attgacaagt aagacttgat cgaagtagtg gggaatcttg ctgaggtcgt ggtgaacgat
    48721 gagaaccgtc ttcccagctt ttttcaaatc tctcagcgta ttcatgatga tttcctcact
    48781 gacagagtca atcccagcaa agggttcatc caagaggata tagtcggctt cctgcaccaa
    48841 acatctggca atcaagaccc gctggaattg acctccagac agttgactaa tttgacgttc
    48901 agcgtagtca gctaggccga cgatttcaag ggcctcttgc actttcttcc aatgtttagc
    48961 ctttaaactt cgaaagagag gaatagaggg aaatagtcct aacgagacgc attccttgac
    49021 cttgatggga aagttgtagt cgatattgat tttttgttcg acataggcaa ttcggtgtaa
    49081 ggatttttta acttccttgt catcgagaaa tgcctgacct tgatgtggga taattcccaa
    49141 catacctttt aatagtgttg atttcccagc gccgtttgga ccaatgatgc cggtaattgt
    49201 tggtccatgg agcactagtg aaatatcctt aagtgccaac gtttctttgt aggagacact
    49261 gaggttttcg atacgtatca taaacttgta ttcctcctgt ctcttaatat acattaaaaa
    49321 aaaaattaag tcaagttaat ttttgaaaaa attaaaataa taactgaaaa atagattcta
    49381 aaaataactt tcaggataaa tttctaaatt ataaaacgca tagtatcaag tgtaaaaaac
    49441 ttggaattat gcgttttatc atggaaagat tttttataat agctaaaaaa taatagttaa
    49501 atggttatta attgcattcc ctagtgattt ttgttaagat aaatgcaaat acaaatgaaa
    49561 gcgagaacaa gatgacacgt tatcaagatg atttttatga tgctatcaat ggagaatggc
    49621 aacagacagc tgaaatccca gcagataagt ctcaaactgg aggttttgtt gatttagacc
    49681 aggaaattga agacctgatg ctggcgacaa cagacaagtg gttagcaggt gaagaagtgc
    49741 ctgaggatgc tatcttggaa aactttgtca aataccaccg cctagttcgt gattttgaca
    49801 agagagaagc tgacggtatc acacctgtct taccactcct taaagaattc caagaattgg
    49861 aaacttttgc ggattttaca gctaaactag cagagtttga gcttgcagga aaaccaaact
    49921 tccttccttt tggtgtatcg ccagacttta tggatgctag aatcaatgtt ctatgggcta
    49981 gcgctccaag cacaatcttg ccagatacga cctactatgc agaagaacat cctcagcgcg
    50041 aagagctctt gactctttgg aaagaaagca gcgcaaatct cctcaaggct tatgatttct
    50101 ctgatgaaga aattgaagac ttgctagaaa aaagacttga attggaccgc cgagttgcgg
    50161 cagtggtgct ctctaatgaa gaaagttcag aatatgctaa actctatcat ccatattctt
    50221 acgaagattt taagaaattc gcgcctgccc tacctttgga tgacttcttc aaagcagtta
    50281 ttgggcaatt accagacaag gttattgtag acgaggaacg tttctggcaa gcagcagagc
    50341 aattctacag tgaggaagcc tggtctctcc ttaaagcaac cttgattttg agtgttgtca
    50401 atctttcaac cagctattta acagaggata tccgtgtttt gtctggtgcc tacagccgtg
    50461 ccctttctgg agttccagag gcaaaagata aggtcaaagc agcttatcat ctagcacaag
    50521 aacctttcaa gcaagccctg ggtctttggt acgcccgtga gaagttctct ccagaagcca
    50581 aggcggatgt ggagaaaaaa gtggcaacca tgattgatgt ctataaggag cgtctgctta
    50641 agaatgactg gctcactcca gaaacctgta aacaggctat cgtgaagctc aatgtgatca
    50701 aaccttatat tggctatcca gaagaattgc ctgcacgtta caaggataag gtagtgaatg
    50761 aaactgccag tctttttgag aatgctctag cctttgcgcg tgtggaaatc aagcacagtt
    50821 ggagtaagtg gaaccagcct gtagactata aggaatgggg catgcctgct catatggtca
    50881 atgcctacta caatcctcag aagaacctga ttgtctttcc agcggccatt ttacaggcgc
    50941 ctttctatga cttgcatcag tcatcttctg ctaactacgg tggtattggg gcagtgattg
    51001 cccatgaaat ttcccacgcc tttgatacta acggggcttc ctttgacgaa aatggtagcc
    51061 tcaaggattg gtggacagag agcgactatg ctgccttcaa ggagaaaaca caaaaagtca
    51121 ttgaccaatt tgatggacag gattcttatg gagcaaccat taacggtaaa ttgactgtat
    51181 cagaaaacgt ggctgacttg ggaggaatcg cagcagcgct tgaagcagct aagagagaag
    51241 cagacttctc agcagaagag ttcttctaca acttcggtcg catctggcgc atgaaaggtc
    51301 gaccagaatt tatgaaactt ttggctagcg tcgatgtgca cgcaccagcc aaactccgtg
    51361 tcaatgtgca agtaccaaac ttcgacgatt tctttacaac ctatgatgtc aaagaaggag
    51421 acggaatgtg gcgttcacca gaggagcgcg tgattatttg gtaatacaaa aaatctagtc
    51481 atcagaaaaa aggcatccaa tcacgtgtga aaaccttgat aggatgcctt ttgtaataga
    51541 aagatttgct ggatagttta cttaaatttc gattgtcatc atcttgctag aaaaagggat
    51601 tgaaggcctt ttcgtgagcg atagtagtag ctggaccatg tcctggatag acatcgtagt
    51661 ttggtagggt gaagagttgg gtctggatac tatgaaggag ttgctccatg ctaccagtcg
    51721 gaaggtcggt ccgtccgata gtttcgcgga atagagcatc tcccgtcaag actaggtgag
    51781 catcaggaaa gactagggaa acaccaccga tagagtgccc tggggtcggt agaaccttaa
    51841 aacgaaattc ctctagttgg tattcttcgt gaaagacaaa ggtgtgttct gcaggttttg
    51901 tgaccacatc tgccatatca tcgtggcgag ggagaccgga gagattatcg acaggagtgt
    51961 agagccagct ggcttcgctc tctgcgatat agacaggagg attgccaaac gtctcgcgaa
    52021 ccaagtccag actcatgata tggtcataat gggcgtgggt caagagaata gcacagatcg
    52081 gtttgttgat cttctcgatt gtctgacgaa tggcttccca atgactacca ggatcgacga
    52141 cgatgaggtg cttttcgcct tctagataat aggtattttc ataggcaaca ggattcacgg
    52201 ttttatggat tttcatacta gctccaatct caaagaatgt actaatactc ttcgaaaatc
    52261 tcttcaaacc gcgtcaactt tatctgcaac ctcaaagcag tgctttgaac agcctgcggc
    52321 tagctttcta gtttgctctt tgattttcat tgagtataaa ttaagtatag cacagttagg
    52381 gagaataggt aaggatttaa aatgaactta aaaaccagca tgactagatg aagacaggct
    52441 ggttatcaat ttatcaatat tggaaaggtg tcaattgccc ttcataggtt gcataaactc
    52501 cgtcattagc ttgtttgata gacgtgatgt ttagagtgct accgtagttg gcttatcatt
    52561 tgtcgctata ttcactataa gttatcctac tgggcaggtt ctggtcgtta gcatagtatt
    52621 gaacgagttt tttatagctt tgctggctga ataggaacag gcagcaaact cctaacatta
    52681 ggagagcaaa gatagaaata gcagtttttt tcataggtat tctccttata aactaaagga
    52741 tagaagaaag tatcttgagg atttttatac tcttcaaaaa tctcttcaaa ccgcgtcaac
    52801 aatctcttca aaccgcgtca acgtcgcctt gccgtatata tgtgactgac tttgtcagtc
    52861 ttatctacaa cctcaaagca gtgctttgag caacctgcgg ctagtttcct agtttgctct
    52921 ttgattttca ttgagtatta attccaaaat ccagtcaagg taccagtgta tgtgatacga
    52981 gttccaccgt ttatctttcg tatcttcaat ggaattgggg aaatcagaaa gtctttgggt
    53041 tacaatatgg tttccgttct tctatctctc cttctatcac ctaagtttaa aatctaactt
    53101 cgtagtatat tatgggccaa taattcagaa ttatcaagca attttgaatt atttttttct
    53161 tattctgttc caatctagtt ttcatattct taaaaaagtg ataaaatggt aggaagaatt
    53221 ggagagtaga gatgccgaaa gaagtgaatt taacaggcga agaagttgtc gctttaacca
    53281 aagaatattt aacggaagag gatgttcatt ttgtccataa ggccttggtc tatgctgttg
    53341 aatgccacag tggtcaatat cgcaaatcag gcgagcctta tatcattcac cctatccaag
    53401 tggcaggtat tttagctaag ctaaagctgg atgctgtaac agtagcttgt ggattcttgc
    53461 atgatgtggt ggaagataca gatgcgacct tggacgattt ggaaagagag tttggtcctg
    53521 atgtgcgggt gattgttgac ggagttacca agcttggcaa ggtcgagtac aaatcgatcg
    53581 aggagcaatt agcggaaaat catcgcaaga tgctcatggc catgtctgag gacatccgcg
    53641 ttattttggt caaactgtct gaccgcttgc acaatatgcg gaccctgaaa catcttcgaa
    53701 aagacaagca ggagcgtatt tccaaagaaa ccatggaaat ctatgccccg cttgcccatc
    53761 gtttggggat ttccagtgtc aaatgggaat tagaagactt gtctttccgt tatctcaatc
    53821 caacggagtt ttacaagatt acccatatga tgaaggaaaa gcgcagggag cgtgaggcct
    53881 tggtggatga ggtagtcaca aaattagagg agtatacgac agaacgtcac ttgaaaggga
    53941 agatttatgg tcgtcccaag catatttact caattttccg caaaatgcag gacaagagaa
    54001 aacggtttga ggaaatctat gatctgattg ctattcgttg tattttagat acccaaagtg
    54061 atgtttatgc catgcttggt tacgtgcatg aattttggaa accgatgcca ggtcgcttca
    54121 aagactatat cgccaaccgc aaggccaatg gttatcagtc tatccatacg actgtttatg
    54181 gaccaaaagg gccgattgaa ttccagattc gaaccaagga aatgcacgag gtggctgagt
    54241 acggggttgc ggctcactgg gcttataaga aaggtataaa ggggcaagtt aacagcaagg
    54301 aatcagctat tggaatgaac tggatcaagg agatgatgga gctccaagac caggctgatg
    54361 atgctaagga atttgtggac tctgttaagg aaaactattt ggctgaggag atttacgttt
    54421 ttaccccaga tggagctgtc cgttcccttc ccaaagattc aggaccgatt gattttgcct
    54481 acgaaatcca taccaaggtc ggtgaaaaag caactggtgc caaggtcaat ggccgcatgg
    54541 ttccactgac aaccaagtta aagacagggg atcaggttga aattatcgcc aacccgaact
    54601 cctttggacc tagccgtgac tggctcaata tggtcaagac tagcaaggcg cgcaataaga
    54661 ttcgccagtt ctttaaaaac caagataagg aattgtctgt caacaagggt cgtgagatgc
    54721 tgatggctca gttccaagaa aatggctatg tggcaaataa atttatggac aagcgccaca
    54781 tggatcaagt tctgcaaaag accagttaca agacagaaga ctccctcttt gcggccattg
    54841 gttttgggga aatcggtgcg attaccgtct ttaaccgtct gactgaaaag gaacgccgtg
    54901 aggaagagcg tgccaaggcc aaagctgagg cagaggagct tgtcaaaggt ggcgaggtca
    54961 aggttgaaaa taaagaaacc ctcaaggtca agcatgaggg gggagtggtt attgaaggtg
    55021 cttctggtct cctagtgcgg attgctaagt gttgtaaccc cgtgcctggt gacgatattg
    55081 ttggctacat taccaagggt cgtggtgtgg ctattcaccg tgtggactgt atgaacctgc
    55141 gtgcccaaga aaactacgag caacgtctcc ttgatgtgga atgggaagac cagtacccta
    55201 gctcaaataa ggagtatatg gcccatatcg atatctacgg tctcaaccgt acaggactgt
    55261 tgaacgatgt actgcaagtt ctttcaaata caaccaagaa tatttcaacg gtcaatgccc
    55321 aaccaaccaa ggatatgaag tttgctaata tccatgtgtc cttcggtatt gccaacctct
    55381 ctacactgac cacggttgtc gataaaatta agagtgtgcc agaagtttac tctgtcaaac
    55441 ggaccaacgg ctagttgtcc tagctcttac tagaaaggct attatgaaaa tcattatcca
    55501 acgggttaaa aaagcccaag tgagtataga aggccagatt cagggaaaaa tcaatcaggg
    55561 acttttattg ctggttggtg ttggaccaga ggaccaagag gaagatttgg actatgctgt
    55621 gagaaaactg gtcaatatgc ggattttttc agacgcagaa ggcaagatga acctgtctgt
    55681 caaagatatt gaaggagaaa tcctctctat ttctcagttt accctctttg cggatactaa
    55741 gagaggcaat cgtccagcct ttacaggggc agctaaacct gatatggcat cagacttcta
    55801 tgatgctttc aatcaaaaat tagcgcaaga agtgcccgtt cagacaggca tctttggagc
    55861 agatatgcag gttgagctgg ttaataatgg acctgttacc attatcctag atactaaaaa
    55921 gagataagaa agaccaagcc cagtcggctt ggtctttctc atctatcata aaatactcca
    55981 aaaagaaatc ggttcttgat atgcttgggg gaagtctctt ttcaggcttt ggcagatgcg
    56041 ataggaaggg atgagatgtc ctaggatgag gagagttccc tgaaggaaaa gtggaatatc
    56101 acttaaagac accaaggaga gaatcatcag gctatcccat aggagaattt gtaaagcaaa
    56161 acgccagaat ctcggtctaa tctgggaata gagttaacta aagtggtcac aaagttggtt
    56221 tgaaagatag gtcaatagca caggatgaaa gaaaatgagc caaccgctat aaatcaaaat
    56281 ccagtcccaa gtaagccccc ttttaaatgt caaaaatgcc agcatgattc catcaatgac
    56341 aaggagttga atggttttga tgaagatgat ttttttcatg ctaaaacctc cttttcctta
    56401 gagacactcc cataaagaga tgtgtttgtc gtaaaagtct ggatagtttt ctcttaggta
    56461 gtcagctgtc atataataaa aagtagaatg gcaagcagtg atgattggca taagagatga
    56521 aaaacgctga gaactaatga aggctaagag aacaaaaaat agaaaatcaa tggtgagaac
    56581 ccctaaatag tagaagcgaa tctttttatt gatttgagga taaatctcag cgaattgatg
    56641 tttgagtcgg acgaccaaga gaaatagcag gagtccttga gcaaggaaga aaattaaacc
    56701 agagagcaag agccactcaa aagatgtctc gagtctagtg ataaaaaatg caaatagtag
    56761 caaatcaata actgcaattg ctataaaatg gattctatag agttttttca tgacaagacc
    56821 tccctctttt atctaacttc attctactcc aaaagaatgg gagttacaac taaaatgata
    56881 aaaatagcag aagggagatt ctcttaagtt ggctagtatt ctttatttga gtttccttct
    56941 attatctaac ttcttcatca ttccagacaa ataaagctcc gattgcattg aggatataaa
    57001 agatgtattt accgatattg gcgaagtttc cttgaatacc agcttttgtc agctgaacga
    57061 aattgtaaat caaccaaaag ccccactgag ttgttagttt taatgcattc aaagcattgg
    57121 caatgaggga cagtgcaaag gcaatagttg ttacgtaggc aaggagattc atcttgcccc
    57181 catatccgat atagttggtc acaaaggcaa agaggaaggc gatgatggaa atgatgatgg
    57241 ccgccaattt tacctgtttt tggctcattt ggttgggtct gccttcttgc gaagcttccc
    57301 acttctttat agcaaaggta taaatgagga aggtgacggg ataggtaatg atggccgcct
    57361 tatttccaag gatataatca atagcaccgg acaaaatggt attaacaata ccaaagtaat
    57421 ttccccattt gcttaatttc cccgtgaaac gagtggacaa catggaaatc ccaacgttgg
    57481 ttacggaaat caatccaaag ggtacaagag ctgtccatga tccccagtct acaaatttat
    57541 cgaggtgtga gttgaggtaa ccagatgcaa tcgcaatccc aacgaccaaa gcaaccccga
    57601 agaggtcaaa ctatttagat gtagcaaaaa tttttagtga ttttttcata ggttaaacta
    57661 cctttctttt tttcaaatat tctcccacca aatgaaagta aaataaaatg atagaaataa
    57721 aaccctgaaa ataa
//
LOCUS       DAYYYC010000005        57719 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.005, whole genome shotgun sequence.
ACCESSION   DAYYYC010000005 DAYYYC010000000
VERSION     DAYYYC010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57719
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.005"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(177..809)
                     /gene="pyrE"
                     /locus_tag="ACHBV5_000288"
     CDS             complement(177..809)
                     /gene="pyrE"
                     /locus_tag="ACHBV5_000288"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFM9966159.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKDDQENWQEG"
     gene            complement(843..1544)
                     /gene="pyrF"
                     /locus_tag="ACHBV5_000289"
     CDS             complement(843..1544)
                     /gene="pyrF"
                     /locus_tag="ACHBV5_000289"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFM9966160.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            1859..1957
                     /locus_tag="ACHBV5_000290"
                     /pseudo
     CDS             1859..1957
                     /locus_tag="ACHBV5_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612010.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2279..2992)
                     /locus_tag="ACHBV5_000291"
     CDS             complement(2279..2992)
                     /locus_tag="ACHBV5_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9966161.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(2985..3818)
                     /locus_tag="ACHBV5_000292"
     CDS             complement(2985..3818)
                     /locus_tag="ACHBV5_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966162.1"
                     /translation="MIEVSHLSKSFGDKIALNDISFTVKEGQIFGFLGPSGSGKTTTI
                     NILTGQLLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSKFY
                     NISKLRVDNLLKRVGLYDSCKMVAGKLSTGMRQRMLLARALINKPAVLFLDEPTSGLD
                     PTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKLVEQGAPSELIQR
                     YNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGKLN
                     A"
     gene            complement(4028..5401)
                     /locus_tag="ACHBV5_000293"
     CDS             complement(4028..5401)
                     /locus_tag="ACHBV5_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HFM9966163.1"
                     /translation="MFYVNSYVFAYKKEGIMYLRGRSMREIAIEPQISQEFINDLFNS
                     CKELLEIEEVLGSKLTFELLNEQILISDEIDIDSRYSRTKGYYSLFYNEEYNKIQNKT
                     VLVLGAGALGCYISLSLSMYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLS
                     QKIHKYNSDVQVVPISIKVSSVEELENIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVS
                     HKISYISGGFNGCYLIIDNIYIPTIGSCFACRNINKDINKYTLSDKTKWPTTPEMPAI
                     LGGIMTNLIIKIFLGCYNEILIDNAYVYNMRNHALSQEKYVLENGECPICKKNNKVKD
                     NNIRAKTFIRSVCFCLLSGGVAFLSAIGQFTVIETQLIVLFLGIIFAIYYAYYNKNIQ
                     TSLENIVWLFSSFEILFLLVNFRTFIQLPVDIFISMIIFLMLWIFIMLGIVCLSYYIT
                     LLFSKEA"
     gene            complement(5385..6182)
                     /locus_tag="ACHBV5_000294"
     CDS             complement(5385..6182)
                     /locus_tag="ACHBV5_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
                     /protein_id="HFM9966164.1"
                     /translation="MGLIDSMKSRKKINIFKISWDFNITLSEKLNYKRFNKNFEKILF
                     GIFPLALILQCFIMYIYRADILTNFQNFPITLNILLFWLLVVIISATIHEFSHAIIAN
                     NYQIEIPNCGIMLLLFNLAFFVDLSGVQFLKNKKQFLKIMLAGIASNSILSLTGLLVL
                     LFTSYKLLGLLFFIINLGMIFINSIPFFQYDSGIILRYLNSNNNNLNFQYIVQLLIAF
                     VIIYFPLSQLLQFLTPNIIVRSIGGVVVSILLSILYMRGRTKYVLRK"
     gene            complement(6568..6690)
                     /locus_tag="ACHBV5_000295"
     CDS             complement(6568..6690)
                     /locus_tag="ACHBV5_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966165.1"
                     /translation="MQDNFLFEEIEEISVPVSDFSAGLATGIGFGLAILALAGC"
     gene            complement(6711..6836)
                     /locus_tag="ACHBV5_000296"
     CDS             complement(6711..6836)
                     /locus_tag="ACHBV5_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966166.1"
                     /translation="MSDEVFLFEEIEEIVAPTDGEFWGGVLLGTGVVLLIGVACC"
     gene            complement(6968..8188)
                     /gene="divIB"
                     /locus_tag="ACHBV5_000297"
     CDS             complement(6968..8188)
                     /gene="divIB"
                     /locus_tag="ACHBV5_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HFM9966167.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQKDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGVYSYTVADKLIMEAEEKAKKEAEEAEKRQEEERKRLEEEQKKQEE
                     ESNRNQTTQRSSRR"
     gene            complement(8198..9256)
                     /locus_tag="ACHBV5_000298"
     CDS             complement(8198..9256)
                     /locus_tag="ACHBV5_000298"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HFM9966168.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(9260..10612)
                     /gene="murD"
                     /locus_tag="ACHBV5_000299"
     CDS             complement(9260..10612)
                     /gene="murD"
                     /locus_tag="ACHBV5_000299"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFM9966169.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQTASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(10716..11357)
                     /locus_tag="ACHBV5_000300"
     CDS             complement(10716..11357)
                     /locus_tag="ACHBV5_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966170.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(11359..13380)
                     /locus_tag="ACHBV5_000301"
     CDS             complement(11359..13380)
                     /locus_tag="ACHBV5_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HFM9966171.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLIDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(13451..13750)
                     /locus_tag="ACHBV5_000302"
                     /pseudo
     CDS             complement(13451..13750)
                     /locus_tag="ACHBV5_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            complement(14114..14368)
                     /locus_tag="ACHBV5_000303"
     CDS             complement(14114..14368)
                     /locus_tag="ACHBV5_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HFM9966172.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(14388..16229)
                     /gene="typA"
                     /locus_tag="ACHBV5_000304"
     CDS             complement(14388..16229)
                     /gene="typA"
                     /locus_tag="ACHBV5_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFM9966173.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPVEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            16391..17116
                     /locus_tag="ACHBV5_000305"
     CDS             16391..17116
                     /locus_tag="ACHBV5_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFM9966174.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            complement(17156..17407)
                     /locus_tag="ACHBV5_000306"
     CDS             complement(17156..17407)
                     /locus_tag="ACHBV5_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966175.1"
                     /translation="MKFKEFLEHERKEENPLFVGILSIILGLLFPIVGLILGIIGLVL
                     AISYQKESQLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(17471..17851)
                     /locus_tag="ACHBV5_000307"
     CDS             complement(17471..17851)
                     /locus_tag="ACHBV5_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFM9966176.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(17851..18120)
                     /locus_tag="ACHBV5_000308"
     CDS             complement(17851..18120)
                     /locus_tag="ACHBV5_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFM9966177.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            18184..19092
                     /locus_tag="ACHBV5_000309"
     CDS             18184..19092
                     /locus_tag="ACHBV5_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFM9966178.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(19146..19901)
                     /locus_tag="ACHBV5_000310"
     CDS             complement(19146..19901)
                     /locus_tag="ACHBV5_000310"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFM9966179.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(19922..20851)
                     /gene="rnz"
                     /locus_tag="ACHBV5_000311"
     CDS             complement(19922..20851)
                     /gene="rnz"
                     /locus_tag="ACHBV5_000311"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFM9966180.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(20866..21489)
                     /locus_tag="ACHBV5_000312"
     CDS             complement(20866..21489)
                     /locus_tag="ACHBV5_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HFM9966181.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(21482..22720)
                     /gene="hflX"
                     /locus_tag="ACHBV5_000313"
     CDS             complement(21482..22720)
                     /gene="hflX"
                     /locus_tag="ACHBV5_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFM9966182.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(22713..23597)
                     /gene="miaA"
                     /locus_tag="ACHBV5_000314"
     CDS             complement(22713..23597)
                     /gene="miaA"
                     /locus_tag="ACHBV5_000314"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFM9966183.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            23718..23888
                     /locus_tag="ACHBV5_000315"
     CDS             23718..23888
                     /locus_tag="ACHBV5_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFM9966184.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(23936..24775)
                     /locus_tag="ACHBV5_000316"
     CDS             complement(23936..24775)
                     /locus_tag="ACHBV5_000316"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFM9966185.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRIDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(24872..25831)
                     /locus_tag="ACHBV5_000317"
     CDS             complement(24872..25831)
                     /locus_tag="ACHBV5_000317"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFM9966186.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(25958..26956)
                     /locus_tag="ACHBV5_000318"
     CDS             complement(25958..26956)
                     /locus_tag="ACHBV5_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HFM9966187.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEREPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNVWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            complement(27006..27623)
                     /locus_tag="ACHBV5_000319"
     CDS             complement(27006..27623)
                     /locus_tag="ACHBV5_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFM9966188.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SFMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(27624..29345)
                     /gene="pabB"
                     /locus_tag="ACHBV5_000320"
     CDS             complement(27624..29345)
                     /gene="pabB"
                     /locus_tag="ACHBV5_000320"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HFM9966189.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(29406..35348)
                     /locus_tag="ACHBV5_000321"
     CDS             complement(29406..35348)
                     /locus_tag="ACHBV5_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HFM9966190.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAEAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPREDEKAPVEPEKQPEAPEEEKAVEETPKQEDTQPEVVETKDEAANQP
                     VEEPKVETPAVEKQTEPTEEPKVEQVGEPVEPREDEKAPVSPEKQPEAPEEEKTAEET
                     PKQEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYSTASYNALGPVLETAKGVYASE
                     PVKQPEVNSETKAEKVAANTDAKQSEVNSETASLKTAISGLNTDKVELENQLKIAQGK
                     TETDFSMESWTVLSTAKNKAQEVKDNGTATQEQINEAEKSLKTALADLSVDKTALGSA
                     IDTATKKNKENYTNQTWAELETVLTAAKSVNTNESKQSEVNEAVEKLTATIEKLVELS
                     EKPRLTLSIEKRDIDRKVTVTYTLENPANTQIKSITATLKKGEEVVKDFVLTEENLKT
                     NHLTALFEKLDYYKEYTLSTDMVYNRGNDDETESISEELIQLNLKKLELKDIQTVSLM
                     KFENGQESQVTHLSDKPTDLSKLYLKVTSSTSKDAVLAVSSIEEEIVENKKIFKIHAD
                     TPELVVRKKDGSLSKGFDYYMERVIPHDGDIYYDFKDLISAMTSNPTGTFILGRDISS
                     RNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIFDLEYPLFDTIKSGVVKDIDFKHVNM
                     VFPDSNQGDNVATIARVIKDKTKIENVNVEGYLEGRDHVAGLVNNLEGNSEIENISFT
                     GKIKSKGGNSITAGIAGRNILSRVKRAYVNANIEVLGSTNSSMLVAVNGTTLNASGGW
                     GAWGRLTESVAKGTLEIKRSGQAGGVTATVWPYGAIDKVVSYAKVTKGKELFGSDGDL
                     NNNWFMQKINNIFGVQGISSGDSGNDSKFKRISEEEAKQKVASYNITAPNLMSDSSLL
                     VDRLNESWKNTDQFESIQDYQSQNQLIYQNLTKFTPYYNKEFIVHEGNALTPEQEILK
                     TKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGSQKRYKVTSTGKFSITNLPEYQVEDL
                     NVVYTSEHIVHPLDSSLINNLVEELKKVELYTESTYQVLGIDKDNANKLNRTKRLFLD
                     ESLDAVKTQLPTFVKTMFENEWLHINGESSGAVAALRQKIMDNKTAILLALTYINRYY
                     DVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRLGSSGENRLKGSENAETFKQLFASET
                     KQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDYIQFEERPSLVEEIKDAKYRVYDNLT
                     APYYQGYILPLLTLKNTHLAILSNYSTMTFVSREKRPNWKNEDFDKWVKYVATAHRNH
                     VDTWYKILPDNIKGKMVKENVTAVWEGLSIPGSEWVDQNAVDRKGRDYAPAREFFNLV
                     GGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSEYGISVFTHELTHVNDTWIYLGGYGR
                     RENMGPEAYAQGLFQSPVPGQPGWGALGLNMAFERKNDGDLIYNASPTQFENRKELDS
                     YMKNYNDTLMMVDYLEGDAVISKGKEAITKWFKKVEPKVVSQTAQYDTVRQLTAEEKE
                     KLSVSSVDDLVDQGLMSDRAVGNNTYNPADFETSYIAIDYMTGIYGGGKNSVGSPGAL
                     MFKHNTFRMWGYYGFEEGVLGYASNKFKQASRDEGHAGLSDNFIISKISKGEFLTMEA
                     FKKGYFKKVVEELKTKGIRPVTINQKTYSTFEELQEGFKQAVERDLKKNQLDERETRN
                     FKFQVFRQLLQQTDSFKTSIFR"
     gene            complement(35370..35933)
                     /locus_tag="ACHBV5_000322"
     CDS             complement(35370..35933)
                     /locus_tag="ACHBV5_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFM9966191.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(36049..37740)
                     /locus_tag="ACHBV5_000323"
     CDS             complement(36049..37740)
                     /locus_tag="ACHBV5_000323"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFM9966192.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(37737..38474)
                     /locus_tag="ACHBV5_000324"
     CDS             complement(37737..38474)
                     /locus_tag="ACHBV5_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFM9966193.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            complement(38832..39944)
                     /gene="msrB"
                     /locus_tag="ACHBV5_000325"
     CDS             complement(38832..39944)
                     /gene="msrB"
                     /locus_tag="ACHBV5_000325"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFM9966194.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            complement(39955..40521)
                     /locus_tag="ACHBV5_000326"
     CDS             complement(39955..40521)
                     /locus_tag="ACHBV5_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HFM9966195.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            complement(40541..41251)
                     /gene="ccdA2"
                     /locus_tag="ACHBV5_000327"
     CDS             complement(40541..41251)
                     /gene="ccdA2"
                     /locus_tag="ACHBV5_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HFM9966196.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            complement(41462..42322)
                     /locus_tag="ACHBV5_000328"
     CDS             complement(41462..42322)
                     /locus_tag="ACHBV5_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFM9966197.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            complement(42501..44555)
                     /locus_tag="ACHBV5_000329"
     CDS             complement(42501..44555)
                     /locus_tag="ACHBV5_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFM9966198.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(44567..44821)
                     /locus_tag="ACHBV5_000330"
     CDS             complement(44567..44821)
                     /locus_tag="ACHBV5_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966199.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            complement(44814..45371)
                     /locus_tag="ACHBV5_000331"
     CDS             complement(44814..45371)
                     /locus_tag="ACHBV5_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM9966200.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            complement(45355..46311)
                     /locus_tag="ACHBV5_000332"
                     /pseudo
     CDS             complement(45355..46311)
                     /locus_tag="ACHBV5_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            46403..46762
                     /locus_tag="ACHBV5_000333"
     CDS             46403..46762
                     /locus_tag="ACHBV5_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HFM9966201.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            46972..47217
                     /locus_tag="ACHBV5_000334"
     CDS             46972..47217
                     /locus_tag="ACHBV5_000334"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM9966202.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTLEERHFYTS
                     YHAFDRPSYHPKMLVSTLLFAYSQGIFSGRKIEKWKS"
     gene            47217..47828
                     /locus_tag="ACHBV5_000335"
     CDS             47217..47828
                     /locus_tag="ACHBV5_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM9966203.1"
                     /translation="MTLDCLFIDRTKIEANANKYSFVWKKTTEKFSAKLQEQIQVYFQ
                     EEITPLLIKYAMFDKKQKRGYKESAKNLANWHYNDKEDSYTHPDGWYYRFHHTKYQKT
                     QTDFQQEIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQRKIDVE
                     PVFGQIKASLGYKRCNLRGKRQVRIDMGLVLMANNLLKYSKMK"
     gene            complement(48076..54777)
                     /gene="bgaA"
                     /locus_tag="ACHBV5_000336"
     CDS             complement(48076..54777)
                     /gene="bgaA"
                     /locus_tag="ACHBV5_000336"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HFM9966204.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIENRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLYKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVKVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKDQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     VPKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEVTVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSFPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKIEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGK
                     ERIFTAINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPSTGSAASQAAVAAGLTLLGLSAGLVVTKGKKED"
     gene            complement(54865..55056)
                     /locus_tag="ACHBV5_000337"
     CDS             complement(54865..55056)
                     /locus_tag="ACHBV5_000337"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966205.1"
                     /translation="MKIKEQTRKLATGCSKHSFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHIYGKATLTKFELDFRRV"
     gene            complement(55082..56557)
                     /locus_tag="ACHBV5_000338"
     CDS             complement(55082..56557)
                     /locus_tag="ACHBV5_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HFM9966206.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            complement(56605..56910)
                     /locus_tag="ACHBV5_000339"
     CDS             complement(56605..56910)
                     /locus_tag="ACHBV5_000339"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM9966207.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            complement(56948..57424)
                     /locus_tag="ACHBV5_000340"
     CDS             complement(56948..57424)
                     /locus_tag="ACHBV5_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFM9966208.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
BASE COUNT        16961 a        12591 c        10314 g        17853 t
ORIGIN      
        1 atcgtcctct taagaagtga taaacaagat agttgattga tcaatttgat acatattaca
       61 ttttcattat atcaataaaa gaaagcgttg tcaattattt tatttaaaat attgtcatat
      121 tttaaataaa atggtaaaag aggctcggta gcctcgtctc tctttatctt actgacctaa
      181 ccttcttgcc aattttcttg gtcgtcttta aagcgtttta gaagatcaag gccctctggc
      241 gtgatgtaac cttcttcttg ggctagatgg ataagctcgc tatagtttga aagcgtcaca
      301 agtttaacac cagcatctgc aaagttctta tctgcttttg gcaattggta gctgaaaatc
      361 gctacaactc caagcacatc tgctccttct cgcttggctg ctgctacagc ttcaagaact
      421 gaaccacccg ttgaaataag gtcttcaacc actaccattt tttgaccttg agctacgcga
      481 ccttcgattt gattaccagc tccatggtct tttggtttgc tacggatgta ggcaaaaggc
      541 aagtccatct tatcagcaat aatggctccg tgtggaatcc ctgctgttgc agttcctgca
      601 atcacttcta cttcaggaaa ggcttctttg atagcttcca caaaaccatt ttcaattagg
      661 gtacgagttt ctggataggc tagtgtcaca cgattatcag tgtaaatcgg tgacttgata
      721 ccagatgccc aagtgaaggg ttcctctggt ttgaggtaaa cggcttggat tttcaagagg
      781 tggctagcga tatctttagc aagtgtcatg gtattctcct tttatttttc taatctagtt
      841 ctttaattcc agtcctgtgt ccattcatcc ttgatggcat gataagctgc aacaggatcc
      901 tcagcttggg taatgggacg tcccactacg atatagtcac tgccgatttg ataggcatca
      961 gcaggtgtca tgactcgttt ttgatctcca actgcaacac cagctggacg aatccctggt
     1021 gtcagacaga taaaatctgg attggtagcc tgcttgatga cttgtacttc ctgagccgag
     1081 caaacaacac catccaagcc agcttcagct gtcttcttgg catagtgaat cacagactct
     1141 tgcagactgg tttggatatt ttgaaactcc tgcatctgag cttctgacgt tgatgtgagc
     1201 tgagttacag cgatcaattt ggcttgactt ccaagacctt cacgcgcagc cttcatcatc
     1261 tctacaccac cagccgcatg aacattggtc atatccacac caagctgaga taggatcttc
     1321 attgctgact tgactgtatt aggaatgtca tgaagtttga gatccaaaaa gacactatga
     1381 cccaaacctt ttaagtagga cacaatctca ggccccgctg cgtaataaag ctccatccct
     1441 accttgagat aaaggctttc ttctgctggg aaaagagcta aaaattcctt gaccgcctca
     1501 aaactaggaa aatcaagagc aatgattgga cgatgttctc gcataggttt ctccttttac
     1561 ctttactagt gagagagtct ggccaacaga agccacgaaa aaaggaacct gccaacagca
     1621 aggttccacg aaaaatgggt agtctccacc ctttcaccgt ctaaccttag ctgcctctct
     1681 ggactgcttt aaaggttttt tactattcta ttatttctac tagcacttgt caagtaaaaa
     1741 catggtcacg tatgtgttga ctgctattga acacctcaca agactctttc caaaagaata
     1801 gttaaagact ttcacttagg acagagaaaa agagtttgct tgttaccctt taattgaaca
     1861 aatgggaatt ctgttttatt ttgcggatgc ctattcatct tggcaaaggg gaagtaatga
     1921 gaatgcgaat ggacttcttc gtgagtattt tcttaaaccg atttggcaac aattaccgaa
     1981 aaaatcctta atggtgcttt gctagcttat taatcaccgt ccccaaaaat acttggatta
     2041 caagacaggt tttgaagcac ttatagagga gatttaaaaa tgttgcattt tttattgcaa
     2101 tttatcagtt atcttatcac ccaaaacttc tgcaattagt atgagcacta ttgttatttt
     2161 tcttttttcg tacactcaaa tcaaaatata gcaataagac tattctgtag aattgctgtc
     2221 aaaaagatca gttcattttt ccttcccact tgtgtttata atcattaaaa taactcaatt
     2281 aagaaatttt ctttttccta atagttatcg taattaaagt taatagaaga acaatccaaa
     2341 taagtagtgt tagattagga attagagttt cattccatga aaatccctcc cattttgtga
     2401 aaaacttagt aaacagtccc ataaaactat aatctgttat cttcgcaact gtcttatcca
     2461 aaccagatag catcggtaag aaagcaacta aaatcatagc aggaagactg ataacctgag
     2521 ctactacttg gctcttcgcg gttaaaccta tcaataaata gaataaaatg atggataaag
     2581 aggttagaag aacgattgta atataattaa aagtatgtac aattgtaact cctaaaataa
     2641 gaggagtagt tcccataatc acaaaagtta gcaaaaaagg aagaaacatc gttgataaaa
     2701 tgtattcgga tcctttaaca ccactcaaca gaagagtttg taaattgtac ttttcttttt
     2761 cttcagacaa gataatagtt ataggacttc caacagccaa agccaaagaa aaaggtaaac
     2821 acatcatcaa aagaactaat gcctgttgat cgttgacctt cccctgtgtt tccataagat
     2881 atttataaaa atatgtgaaa gcaaaaggca ctaaaacttg caataaaata ctcttattgg
     2941 aaaggataat ttgacaacgc aaccatacca aagccagaaa ccgtttaagc atttagcttt
     3001 cctcctgtta atgtgataaa aatatcttct aaagtaggct cacatgaatg aattgaaaaa
     3061 atattttcca gatcagcctg agatacctgt tctagtgatg taaaatcaaa agttatctga
     3121 ttcccattat aatctgtaac cttaatcttt ttatctttat tatatctttg aatgagttca
     3181 gaaggagctc cttgctcaac taatttccct ttatttaata aggcaacata atcacataaa
     3241 agagttgctt cattcatatc atgagtcgtt agaaaaatcg ttgtccctgc tgttttcaat
     3301 tctaaaatta actcatgaat tgttcgagaa gttgtgggat ctagacctga ggtcggttca
     3361 tccagaaaga gtacagcggg tttgttgata agagctcgtg ctaaaagcat tcgttgcctc
     3421 attccagtgg ataattttcc tgctaccatc ttgcaactat catataatcc tactcgcttt
     3481 aacaaattat caacacgtaa tttactaata ttataaaatt tactataaaa aagaagattg
     3541 ttatacagag acattttctc ataaaatcca cttgtatcgc taaccaatcc aattctcttt
     3601 aattcaccgc ttgttaaatt ttgagatttt tgtcccaaaa taatagattg tcctttatcg
     3661 gcaaggagct gcccagtcag aatattaatc gttgtggtct ttccagaacc agatggtcct
     3721 aaaaatccaa aaatctgacc ttctttaaca gtgaaactta tatcatttaa agctatttta
     3781 tcaccaaaac tttttgataa atggctaact tcaatcatac tcattgcccc tcctttatat
     3841 tctacatttt tacttaacat ctatttactt agctttatca aataaacgtc ttaaaaaaaa
     3901 caataacatt aagcatataa ccgttagcaa gattgtttca atattattga taatatgata
     3961 cattctcaag cagtataaaa taattatata tatgcaaatg ctcattatac ctattttttt
     4021 aaacatacta agcctccttg ctaaataata aagttatata ataactaaga cacactatac
     4081 ctaacataat aaatatccac agcattaaaa atattatcat actaataaaa atatccactg
     4141 gtaactgaat aaatgttcta aaattaacaa gcaaaaataa aatctcaaac gatgaaaaaa
     4201 gccatactat attttccaat gatgtttgaa tatttttatt gtagtaagca taatatatag
     4261 caaaaataat acccaagaac aatactatta attgtgtttc tataacagtg aactgcccaa
     4321 tagcagataa aaaagctact cctcctgata ataagcaaaa acaaactgaa cgaataaatg
     4381 ttttcgctct aatattgtta tctttcactt tattattttt tttacaaatt ggacattctc
     4441 cgttttccag aacatatttt tcttgactta gagcatgatt tctcatatta taaacgtaag
     4501 cgttatctat taggatttca ttataacatc ccagaaatat tttaattatt aaattagtca
     4561 ttatccctcc caaaatagca ggcatctctg gtgtagtcgg ccactttgtc ttatcagata
     4621 aagtgtactt atttatatct ttgtttatat tccgacaagc aaagcaagaa ccgatggtag
     4681 ggatatatat attatcaata ataagatagc atccattaaa ccctcctgat atgtaggata
     4741 tcttatgcga tacagcaaat tgattgacaa tttttataat atcaatgggc gtatcaattg
     4801 ctttaacgat aaaatctata ctcccatatt ccgcaacaat gttttctaat tcttctactg
     4861 aagaaacttt aatagaaata ggtactacct gaacatctga attatacttg tgtatttttt
     4921 gagaaagaac attaatcttc tccttaccaa catccgactc tgtataaaga atttgcctat
     4981 ttaaatttga tggttctatt atatcgtaat cagcgacaat aagtttcctc actccataca
     5041 tacttagact tagagatata taacatccta aggctccggc tcctaatact aatactgttt
     5101 tattctgtat tttattatac tcttcattat aaaataacga atagtaacct ttagttctag
     5161 aatatctact atcaatatct atctcatccg aaattaaaat ttgttcattt aatagttcaa
     5221 atgttagttt actacctaat acttcttcta tctctaatag ttccttacaa ctattaaata
     5281 gatcgttgat aaattcttgc gaaatttgag gttctatagc tatttcccgc atactccgac
     5341 cacgcaaata cattatacct tcttttttat aagcaaaaac ataactattt acgtagaaca
     5401 tatttcgtcc ttcctctcat atataatata gaaagcagta tagaaacaac tacccctcct
     5461 atactacgaa caataatatt aggtgtcaaa aattgtaata gttgactcaa agggaaataa
     5521 ataataacaa atgctattaa aagttgaact atatattgaa aattcaagtt attattgtta
     5581 gaattcaagt atcttaaaat aataccacta tcatactgaa aaaaaggaat tgaattaata
     5641 aaaatcatac ctaagttaat gataaaaaat aagagtccaa gcaatttata cgatgtgaac
     5701 aataaaacaa gtaaacctgt aagtgataaa atcgaatttg aagcaattcc tgctaacata
     5761 attttcaaaa attgtttttt attttttagg aattgcaccc cacttaaatc tacaaaaaaa
     5821 gccaaattaa acaaaagtag cattattcca caatttggga tctcaatttg ataattatta
     5881 gcaattattg catgactaaa ttcatgtatc gttgcagata taataacaac aagcaaccaa
     5941 aataaaagaa tgtttagcgt tattggaaag ttttggaaat tagtcaaaat atccgcccta
     6001 taaatataca taataaaaca ttgcaaaata agagccaatg ggaaaatacc aaataggatt
     6061 ttttcaaaat tcttattaaa tcttttatag tttaattttt cagataatgt tatattaaag
     6121 tcccaagata ttttaaaaat atttatcttt tttcgtgatt tcatagaatc tataagtccc
     6181 attttactaa gaacaatata aaatcttaaa taatatttct tccctactaa cactaataag
     6241 tccgatatgg taaattcttg acctattagt tgctctaacc atttttttcc tgtttcccaa
     6301 ctaatacatg tttcttactg gatggtatat atagatgata ctgtccctca taaggagtag
     6361 gtaatatctt aatcttatca acaattctca taacaaacct aacctttaat aaataaaaga
     6421 ggggctaagt aaaacatact ctagtccctc agtccgcaat caataaaata atgactaatt
     6481 ctattaatct cttgctgcaa gactaatacg gaaaattcaa atgactgtct aaattgaaaa
     6541 agcttgatat tagtaagtga acaaacttca acaaccagca agagcaagga ttgctaaacc
     6601 aaatccgata cctgttgcaa gtccagctga aaaatcacta actggtactg aaatttcttc
     6661 aatttcctca aataaaaagt tatcttgcat gattatcact ccctatcttt ttaacaacag
     6721 gctactccaa ttaagagaac taccccagtt ccaagtaaaa ctccccccca aaattcacca
     6781 tctgtagggg ctacgatttc ttcaatttct tcaaataaga atacttcatc tgacatatgt
     6841 gttaccttct tcataaaaaa tttttttgta atcgattaca ttgcaaatgt aacataaaga
     6901 aaaacagatg tcaaatatta aacgtaaaaa catggcaact aaagagctat aggagaaaag
     6961 gtaaaaccta gcgacgcgat gagcgctggg tcgtttggtt tcgattgctc tcttcctctt
     7021 gttttttctg ttcttcttct aaacgtttac gttcctcttc ctgccttttc tcagcttctt
     7081 cggcctcttt tttagctttt tcttctgctt ccataatcaa tttatccgct acagtgtagc
     7141 tgtagactcc agcttccatg tcaatcacac tcggttctga caattgtggc ttaatcttac
     7201 tgtaatatgg cagtttctta ctcatttcag atagaggaac caagacttcg tccgaatcat
     7261 tcatggtcaa tcgaattaaa tcggatgtca ccttgcttgg ggctaattcc accttttgga
     7321 tagccgcctt gagttctggg ctaatttgag caagttctga gacaaaaacc ttgatttgtt
     7381 cactatcatt aaagagaact gataaataag tttctggtaa actgttcaga ctcacagaac
     7441 tagtctcaag ctgaccactg gaaagaatag gataatgatt ttcaccagaa atatagtagg
     7501 ccacaatatc atattccttg accttaatag tgaacttagt tggaaattga tagacaagtt
     7561 gagctgattc aacccaatag ttagacttaa tctgcttttc atattttgcc ttgtctagca
     7621 gaaggttaat cgtataatcc gaatcctgaa tgcctgaagc ctgtcgaata tcatcagctg
     7681 tagtttgcac cgttccctca acacgaatat ctttcatggt cgcataagga ctgagcaagt
     7741 aggcagagac aatcaataaa agcagacttg gaaataaaat cgtgaaggct cgcaagatat
     7801 ggataccagg aatctttgct ttggctggtt tttcctttgt agccttttta gcaagctttt
     7861 tatcctgttc ctccttctct ttagactctg gttcttcttt ctcttctttc tctttgtcag
     7921 cctctgagga tgctactttt tcttcagact cttccttagc tgattctgaa tctttctggt
     7981 ctgtttcact ctcctggtcc tgtttatcct ctgacttctc agattcttct cccattcgag
     8041 cttgtctttc cttttccttc tcctcagcta gagccgcctc ttcttcagcc ttctttttta
     8101 gatattcttg gtttcgtttc tgccattctg ataactcttt caattcttcg agggtttctt
     8161 tgtcctcatt tttcttatct tttgacattt actttcctta tgataaatct tttttcaaca
     8221 attgataaaa atctgctaga gatttcaatt ccttagaagc tttcatctta gcttggtaat
     8281 cttccttgtg acttagtaag tgagaaagct tctcttccaa actatccaag gtcaaatcgc
     8341 tttcttgaag gtcttctgca tagcctttct taacaaagta agctgcattt tcaatctggt
     8401 caccacgact agcttcacga ccaagcggca caatgacatg caattttgct atcgccaaga
     8461 gctcaaaaat cgtattggca ccaccacgtg tcacaacaat atcagccaat tccatcaagg
     8521 gttgatagag atcggtcaca tagtcaacac gaaaaagatt ttggctcaac tcattcaggc
     8581 tagaatctcc agttagattg ataatattgt agcgctctgt tagttctttt ttatggtctg
     8641 tcaccaattg gttaaagaca cgagcacctg cagaaccgcc aacaaacaat acagtcggca
     8701 atttatgatt aaagtggctt tgaatatcca ccaattcatc tggttctgga tttttttgat
     8761 ctgaaacctt ggtcactgct cccacatgct caaccttagc caaactcgaa gcttgttcaa
     8821 aggttgaata catcttagtc gcaaatttat aggcgatttt attggccaag cccatagaca
     8881 ggtcagattc gtgaataaag acaggcactc ctgacacacg cgcagcgata acaggcggta
     8941 ctgagacaaa gccccccttt gaaaaaaggg tctgtggacg aagtcgcaac atgataaaga
     9001 gcgattggac gattccccag ccaactttga agacgtccag catattttgc caagagaaat
     9061 agcgacgcaa tttcccagtc gcaatggagt ggaaagtgac atccaaacct gacttaagga
     9121 tttcttggtg ttcgatacca cgcttgtccc cgatatagtg gacttcccaa ccatcttcga
     9181 tgaacttggg cattaacaaa agattgaggg taacgtgtcc aaccgtcccc ccacctgtaa
     9241 agacaatttt tttcatattt tattctttta actccgctac tgtgtcgata aagaggtcgc
     9301 cacgtacttc aaagttagca tacatatccc agctggcatt ggcaggacta agaagaacca
     9361 catctccttg agtcgcaagc tcataggcct tgcgggtcgc atctgcaata tctgtcgcct
     9421 ccacataagc gacaccagcc ttgtctgctg cccgtttgac acgttctgca gattgaccca
     9481 ggatgaccat cttcttgagt ccagtaatat ctggcaccaa ttcgtcaaac tcattgccac
     9541 ggtccaaacc acctgcaatc aagacgacct tgctgttgtc aaatcctgac aaggcttttt
     9601 gagtagccaa gatattagtt gatttactgt cgttatagaa tttaacaccc ttgatgtcat
     9661 ccacaaactg gagacggtgt ttgacaccac cgaaggctga aagagtttcc ttgatggttt
     9721 gattgtccac accacgaagc ttggctacag caatagtcgc aagggcattt tccacattgt
     9781 ggctacctgg aacaccgatt tcattcgctg ccatgactac ttcaccacgg aagtagagtt
     9841 gaccatcttc cagataagct ccatcaacct tttcaagtgt tgaaaatggt acaacagtgg
     9901 cttctgtctt ggaagtcaag tcttttgcca agtcttgatt aaagttcaag acaaggaaat
     9961 cagctgctgt catcttgttc tggatattcc acttggctgc tacatattcc tcaaataatc
    10021 catgataatc gatatgagtt ggcataaggt tagtaataac cgcaatctct ggatgaaatt
    10081 cttgaacacc catgagttgg aaagaagaaa gttccataac aagcgtgtcc ttgtccgacg
    10141 cagtttgggc cacttgacta gctggatagc cgatattccc tgataaaaga ccatgttgcc
    10201 cagcagcagt caaaacttcc ccaatcatag tcgttgtggt tgtcttaccg ttcgatcctg
    10261 tgataccaat aatcggtgct tctgaaatca aataagccaa ttccacctca gtcaagactg
    10321 gaattccctt ggccaaagcc ttttcaatca tgggattgtt gtaggggata cctggatttt
    10381 tcaccataag ggcaaactct tcatccaaga gttccaaagg atggccacct gtaatgacct
    10441 tgatcccttc ttccagcaaa ctttgggcag ctggattgtc ctcgaatggt ttcccgtcat
    10501 ttactgtcac tatggcgcct agcttatcca acaaacgagc tgcagattca ccagacttgg
    10561 ccaaacctaa aacaagaact ttcttatttt taaattgatc tattactttc atgtctcgaa
    10621 ctccatttct actcctacta ttttaccatt tttatggaaa taaaaaagcc acaaagtgtg
    10681 tttgtgactc tttcttctaa ctgaatctta ccatattatc tatgtgataa atcggtaact
    10741 cgaatgacct gatccacttg ctcccaaatc agaggattgt gggtcgcaat aataatggtc
    10801 cgattcggat tttttaaaga ttctaggatg gaaagtaatt cctcagagtt tttggggtct
    10861 aaggaagcgg ttggttcatc tgcaagaatc aaaggcggat cctttaaaat tatcttcgct
    10921 aatgcaacac gttgtgcttc tcctcctgat aactcaaata taggttgctt caaatccaaa
    10981 taagagaggt ttacacggtt tagagcttgt ttcatcaaag agattttctc tttttccttc
    11041 aactttttac caactaaacc cagattgaga ttctctttga cggtttggct ttcaattaag
    11101 ccaaaatctt gaaataagta tcccaagtaa tctctaaaga aaacagaagg cttgatgtcc
    11161 ttaagagaag tgccatcata gatgatttgc cctttgtcat atggctctaa tcgtccaatc
    11221 atattcaaga gtgttgtctt accacagcca cttgtaccga ttaaggcata aattttccca
    11281 ccttcaaaat gaagatttgt atctgaaaat agctgacggc ttccaaattt tttagatata
    11341 ttctttagtt caatcatcct attttccttt cataattgtc atagaaacac gagattcttt
    11401 ctgcgcttga cggtaaagcg tcagaactgc actagctaga aagactaata aagtgagcaa
    11461 gccaatcacc aagtctcgac tgcttaaaat aaagagacta gcaccaaata caaaactggc
    11521 aaattgacta accatatact gagcatgtgt ttcaaaaaat cgtaaacctg aaattcgttt
    11581 aatcaaaata tctcggcgga attgctcgaa atatagaaga ttgacagaat aaaatagtaa
    11641 caaggaacta gctatcccca caatagctcc taagattaaa gttgctgttt cagtttgaac
    11701 ttcattataa cgagttagat aaacacttct tccttcttta agataggata cttgctcata
    11761 aattccagct ttcttcaaga gttctagccc actctcatat cctttgataa agagttgttt
    11821 tccagcattg atagaccaac tagataagga tataaaacta tcacctgtag aagtcggcgt
    11881 gaatacaact aaaatcggat caatcaaata ctgagtggat acgggattct caccgttatt
    11941 ataaacaaac cgcttttctc ccattgaaag ataactaacg tgcgctttca tctcataatc
    12001 caaaggagca cttgcctcct caccagattt tccataataa ctcaatcttt cttcaaaaac
    12061 tttcttaagt tctgcttctc gagagcgcaa atgttctggg agcaagagga taaactcacc
    12121 tttttggaga tgggctaact tctgtttggt ctcagcatct accacgacct tttccttgtc
    12181 caaataactg ggactaacat agagcgtatt agcatctgga ctataggtat ccagtgtctc
    12241 tccctgttca ttttttcctt gtggattggc aaaatggagc agattatcct ttacataaag
    12301 agcttgttct tcttcgattg cttccttggc aaaggcatac cacttgctct gattttctgt
    12361 atcttttcct ctatcaccta agccaaaaga aatttgataa tagtctgctc tatcctgcca
    12421 tgcttgtttt gaaatttcaa gttctttcaa tcgttggtaa gacgtcaaac ctgtcttaac
    12481 agcgtatcct actgtaaaga cagcaaccaa ctgacacaat agggttaaaa tcatcaggcg
    12541 tttaaggggt aatctcccct taataacggg aactaatgct ttgtaattca aactcattag
    12601 ataaagaagc attagtaaaa ttgaaatcgc caataaaaac aacagataga aactaatccc
    12661 aaaaccatag gtggctaaca agataggata aaacaaacct tgactaaaaa gaacgactcc
    12721 cccacctagg aaggaaagga gggctgatag aaggagccat ttgatatcag tagataaaga
    12781 atgccccatg atggataaga gagtctgacc agaaaagagt tttatacctg ctgctctcat
    12841 ttccttaatc cgagtgataa tcactaaagc aaagaaagat aaaccaaata ttgctaaact
    12901 aattaaaata aggggattta gtaatattcg aaaagcaaga aaatagggcg gtatctttcg
    12961 gtcagcactt gctttataac ccaaatctcc taatttatcg gcaagctttt ctttcgtcaa
    13021 ggagcctgac aaaaggagat aactatttag cggatcacta cgttcacgac tttcttggct
    13081 agcttcttgg aattcttttg gtaaagttcc ctgaccataa gttgcataag taaagtgagt
    13141 cgtcccatcc ttactcggct ctacaattct tctagctatt aaactctgtt ctgagtttgc
    13201 aaaattctcc aattcctgtt caaatacctc acgcgtcggt tcctgagtat cttttttgac
    13261 acgaagtaaa gaaacggaat catagcttgc atataaatat tgtggcgcac gtaagacaat
    13321 aatccaagca aggaagaagc tgagaaaaaa agttgataat aatatgaata gtttcttcat
    13381 agtagactcc ttgtaaacaa aattccccct gtaatttctt acaaggggaa cgatttaaat
    13441 caatgaacga ttagtcataa tcacagtaaa atgctacttg ttctccccat ttagtccaaa
    13501 tccatgcata ggaggttttt ccagcaggag cttctccttt atcagaatga ccatcccatc
    13561 tgctcacgat ggatgaataa tgatattttt taccatgata gtaatttgaa aaagcctaac
    13621 cacctcctga accttctcca tatgtccata ctcctccatc tggatattgt acagcagctg
    13681 atgcagctcc caataatgta aaatttgaaa taagagctag agcaagtaat ctatgttttt
    13741 tcgttttcat tttatttttt ctttcaaaaa aatcacacct tgagcaacaa tgcaacaaaa
    13801 taaatcctcc tctctctttt gttgaaatcg ctttcttatg tgataagaat aacattttta
    13861 ttatttgttg tcaaggaaaa aatcgaattt tttagatgtt ttactatatt atctctatga
    13921 ataatattat atagtagttt tatttcaaaa taatatgcaa ccagtactaa ccaaatataa
    13981 aatagatgcc attaacgaat tttattcaag tttttcccat tcatactata caagtaaaag
    14041 agatggtgtt aactaaaaag caattcaaac tattgtaaaa ttcctagcaa aaagagagcc
    14101 gaaactctct tttttatctt cttttacttt ttttgactgg catgagtgtg atgtctctaa
    14161 cactaaagta agctaggatc aacatggcta ttgctaggaa tatttctgtt ggtaattgaa
    14221 aaattttcag aaaagataga accaataaaa tcaagagtgc cactaaaata cataccatag
    14281 cgacgatatt gacagtccct ttaatgcttt ctggtgtcgc aaatacatag agtaggagca
    14341 gtaaaattcc taggactaaa tagaccatct ttctctcttt ctagctctta ttcagctgat
    14401 tttttcttct tgttagcttt ctcacgctct gctttgttaa ggatttgttt acgcaaacgg
    14461 atagactcag gcgttacttc catgtactca tcgtcgttca agaactcaag agactcttca
    14521 agtgtcaaga tacgaggcgt cttgataaca gctgtttggt ccttagtagc tgaacgaacg
    14581 ttggtcattt gttttgcctt cgtgatgtta actgtcaagt cattttcacg agagttttca
    14641 ccgatgatca ttccttcata aacctcagta cctgggttga caaagatcgt accacgttct
    14701 tcgatagaca tgattgagta agttgtagcc ttaccagcat cgatagaaac aagggcacca
    14761 cggtgacgtc caccaatttc ccctggaatc aatggcaagt attggtcgaa ggtatggttc
    14821 atgataccgt aaccacgagt cattgacaag aactcagttg agtatccaat caaaccacgc
    14881 gctggaacaa ggaagaccaa acgagtttga ccattaccag ttgaaatcat atccaacatt
    14941 tcacctttac gttcagaaag gctttggata acagaccctt ggtattcttc tggagtgtcg
    15001 atttgtacac gttcaaatgg ttcacattta acaccgtcga tttcttttac gataacttct
    15061 ggacgagata cttgaagttc atagccctca cgacgcattg tttcgataag gattgacaag
    15121 tgcaattctc cacgtcctga aacagtccat ttatctggtg aatcagttgg gtcaacacga
    15181 agggaaacgt ctgtttgcaa ttctgcctgc aagcgttctt ccaccttacg agaggttacc
    15241 catttacctt ctttaccagc aaatggtgag ttgttgacca agaaagtcat ttgaagagtt
    15301 ggctcatcga tgtgtaggat tggaagagct tctactgcat ctgtcggagt gatggtttca
    15361 ccgacaaaga tgtcttccat acctgaaacg gcaatcaagt cacccgcttt ggcttcttgg
    15421 atttcacgac gttccaaacc aaagaaaccg aagagttttg taacacggaa gtttttagtt
    15481 gtaccgtcaa gtttagaaag ggtaacttgg tccccaacct taactgtacc acggaagaca
    15541 cgaccgatac cgatacgtcc aacgaagtca ttgtagtcca aaagcgacac ttggaactgc
    15601 aaaggctcat ctgagttatc tactggagct gggatatggt cgataatcgt gtcaaagatt
    15661 ggtgccatag tcgcttcttg gtcagctgga tcatctgaca atgaagaagt tccgttgatc
    15721 gctgaagcat aaaccactgg gaaatcaagc tggtcgtcat ctgcaccaag ctcgatgaaa
    15781 agttccaaga cttcatccac tacttctact ggacgagctg atggcttatc gattttgtta
    15841 acaaccacga ttgggacaag gtcttgttcc aaggcttttt tcaatacgaa acgagtttgt
    15901 ggcatggttc cttcataggc atctacgacc aagacaacac cgtcaaccat tttcatgata
    15961 cgctcaactt ctccaccaaa gtccgcgtgt cctggtgtgt ccataatgtt gatacgagtt
    16021 ccgttgtaag caacggcagt atttttagca aggatggtaa tcccacgctc tttttcgata
    16081 tcgtttgagt ccatagcacg ctctgccaat tcagtacgtg catcaagcgt ttctgattgt
    16141 ttcaataatt cgtcaacgag ggttgtttta ccgtggtcaa cgtgggcgat aatcgcaatg
    16201 ttacggatat cttctcttaa ttttgtcatg atttcctcta taatattcaa aatttatttt
    16261 ctaactgaac gattatacca taatttcaaa taaataacat aactcaagca agtgtaaatg
    16321 ttttcactcc gcttttcttt tcacgtcaag ccttttcaaa gcaagcgact tatgataaga
    16381 taggcacagt atgcgtttag ataatttatt agctcaagaa aaaatcagcc gaaaggccat
    16441 gaaacaagca ctcctcagag gggaaattct agtcgatggt tgcccagccc gctccctagc
    16501 tcaaaatatc gatacaggac tacaagaact cctttttcag gatcgaatca ttcaaggcta
    16561 tgaacacacc tatcttatgc ttcataaacc tgctggtgtc gttacagcca acaaagacaa
    16621 ggaacttccg accgtcatgg acctgcttcc atctgacatc cagtctgaca agctctatgc
    16681 cgtcggccga ctggaccgag atacaacagg actccttctc ttgaccgata acggtccctt
    16741 gggcttccaa ctcctccatc cccaatatca tgtcgataag acttatcaag ttgaggttaa
    16801 tggacttcta acacctgacc atatccaagc ctttcaaaag ggaattgtct ttttagatgg
    16861 tactgtctgt aaacccgcaa aactagagat tctatctgca agtccctcca tcagtcaagc
    16921 ctctatcacc atttcagaag gaaaatttca tcaaatcaag aaaatgttcc tctcggttgg
    16981 tgttaaggtg actagcctca agagaatcca atttggggac ttcacattga acccagattt
    17041 agcagaaggt aactaccgcc ctttgaacca aaaagagtta caaatcatta aaaactattt
    17101 agagatgagt cgataaaata aaaaaagctt taaaactaaa gcttttttct tttatttacc
    17161 gaaaaattaa ggcgattgct acaatccagt taactacaga aatcacaatt cctaagatat
    17221 taagaatctt ttctatttta tagtctaatt gtgactcttt ttggtatgaa atagccaaga
    17281 ccaatcctat gatacccaaa atcaggccta caattggaaa taacaaacca agaataatcg
    17341 acaagatacc cacaaaaagt ggattttctt cttttctttc atgttctaag aactccttaa
    17401 attttataca aattaattat actataaaac aatagcttca tcctatcatt caactaattt
    17461 ggaaataagg ttagctagtc ttcactttcc ctttccaaga atccaagcca taagaaagga
    17521 tataaatctc agaaaaacct tgttttttca agtaaagagc tgcatttgta actcgttgcg
    17581 cacgttggtt ttcgtagaga aggacaggtt tatctttacg aagggctgca agactagttt
    17641 tcaactgact tgaaggaata ttgcgtgcac caaggatatg ttttctgtgg aattctgctg
    17701 ggtcgcgcaa atcaatcaat tgacccgtac gaatcaaggc ttcaaactcc tcattgtcca
    17761 caattttagc cgcacggcga atacgaagat agttaaagcc catccacgcc aacattgcta
    17821 gtataagtgc ccacaaaatc caagtaacca ttagttcttt tctccatttt tctcaatata
    17881 atccaattct accttgtgct ctctgcgaag aactgcttct gcctctagat agtctaattt
    17941 atccatcaac cctgcatcgt aaatccgaga tagttccaac ttcatcagtt caatatcata
    18001 taagcgtttt cccatgtaaa caataatacc aaatcgtttg aggaattgct gcacatcata
    18061 gaatgttttc ataagactca ttctagcaaa attttgtgtt tttttcaaga agagactcac
    18121 acaatgctcc ttattttccc atcttcttta gcgattctaa ggcaagtatg gtacaataaa
    18181 aacatgagaa ttcaacaatt acattatatt atcaaaatcg tcgaaactgg ctccatgaat
    18241 gaggcagcca agcaactctt tatcactcag ccaagtctct ccaatgcagt gcgagatttg
    18301 gaaaatgaaa tgggcattga gatctttatc cgcaatccca agggaatcac cttgacccgt
    18361 gatgggatgg agtttctctc ctatgcccgt caggttgtcg agcagaccca gcttctggag
    18421 gaacgctata aaaatcctgt cgcccaccgc gaactattta gcgtttcgtc tcaacactat
    18481 gcctttgtgg tcaatgcctt tgtctctttg ctcaagaaaa gcgatatgga gaaatacgaa
    18541 ctcttccttc gtgaaactcg gacttgggag attatcgacg acgtcaagaa cttccgcagt
    18601 gaggtcgggg tcctcttctt aaacagttac aaccgtgatg ttttaaccaa gatgctggat
    18661 gacaatcacc tgctagccca ccatctcttc acagcgcaac cacatatctt tgtcagcaag
    18721 accaaccctc tggcaaagaa agacaaggtg aaactgtctg atttggagaa tttcccttac
    18781 ctcagctatg accaagggac gcacaactcc ttctactttt cagaagagat tctttctcaa
    18841 gaacaccaca agaaatccat tgtggtcagt gaccgtgcca ccctctttaa tctcttgatt
    18901 ggtttggatg gttataccat tgcgacaggg attttgaaca gcaacctaaa cggagacaat
    18961 atcgtttcta tcccactgga tattgatgac ccgattgagc tggtctatat ccagcatgag
    19021 aaaaccagcc tatctaagat gggcgaacgc tttatagact acctcctaga agaagttcag
    19081 tttgatagtt gagaaatgat aagaaccaat atgtaggcta gcaacaacct gcacattggt
    19141 tctttttact tataattaaa agtttcccct gccaacttat cagctagctt aggaaagagg
    19201 gtataaaact tatgagctag gttcaacaaa atcgggagat tgagttctcg tttgtttttt
    19261 cctataatct tgacaatctt tttagccact gcatctggtt ctagcaggaa gcggtcaacc
    19321 gatttaagat aagttccatc tgggtcggct tggtcgaaaa atcctgtacg gattggtcct
    19381 ggattgactg ttgtcacata gactccatag ggcataagtt cgagtcgcag agcatttgaa
    19441 aaaccaatag ccgcaaactt ggtcgctgag taaagactag acttgccagt agctattaga
    19501 cctgccatgc tgacgatgtt gatgatatgc cctttgctgc tttccttcat acgagccgca
    19561 aggtgacgag acagattcat cagggcaaag gtattgacct caaacatctg gtgaatatct
    19621 ttatcagcaa tctggtcaaa tccctcaaaa atcccgtaac cagcgttgtt aatcaagaca
    19681 tcaatcttgc catagcggag ataaagatca gttaccagag cttctagggc tgaatcgtcg
    19741 gtaatatcaa tttcaatcaa ttctgcatgg gaataatttc cgtagagttg ggctaatttt
    19801 tccttatttc taccaagcaa gatgagttgg tcattgggca ggagtttgac catttcttga
    19861 gctagaccac cgctagctcc ggtaatgaga atagtaggca tacttatcct ttctgtgact
    19921 gctagatttc cacttcttcc aagtctttga ccacatggac attttcaaaa attgtggcag
    19981 cgtccttctt gagtttgctt atatcttttg agaggaaacg ggcactgata tggttgagta
    20041 ggaggcgttt ggcacctgct tctaccgcta cttgtgcagc ttgcatatta gttgagtgac
    20101 catggttacg agcaattttt tcatcaccct tgccataagt ggactcatga actaggacat
    20161 ctgcattgac agccagacgc acactggcat ccgtttttcg agtgtctcct aaaatagtga
    20221 taatcttacc tggacgtggc gctgagatat agtctgctgc cttgatttca gttccgtctt
    20281 ccaaaacaag atcctggccg tttttgattt taccaaaaag cgggccgaac ggaacaccag
    20341 cagccttgag tttttcagca tccagcgtcc cttctagatc cttttgcatg acacgatagc
    20401 caacacagaa aatagtgtgg tccagctcct ctgcatacac agtgaattta tcggtttcaa
    20461 gaattttacc cagagaatct tggtcaaact catggaaatg aatgcggtag ggcagacgag
    20521 aacctgacac acgaaggctg gttaagacaa atgacttgat tccttgaggt ccgtagattt
    20581 ccaaatctgt ctgctcttca ttggcctgaa aggcacggct agaaaggaaa cctggcaaac
    20641 caaaaatgtg gtctccatgc agatgagtaa taaagatttt gctgacctta cgtggtcgaa
    20701 ttgtggtttc cagaatgcga ttttgcgtac cttctccaca gtcaaagagc caaacttcgt
    20761 taatctcgtc caaaagtttc agggcgagac ttgaaacgtt gcgggcttta gagggctgac
    20821 cagcccccgt tcctaaaaat tgaatatcca ttcgatactt tctaattaat caatatataa
    20881 catggctgtg cggttttccg atcggaaata gcgtttgcca gaaaaagcag cagcttcttg
    20941 caataaatcc tcttggctgt agcctttgag acgttttcga ccatcagcca atctttccaa
    21001 atcagtcaaa gctgtgagac tttctaggct gacaacttcc tcgtccttga caggcttcat
    21061 gtaaatctta ccagactctt caaagactaa ttgatgggag aaaatttgcg caatttcaaa
    21121 gagcaagtca tccgagattt tctcctcatt ttcagagaaa atccgaccaa agccgtcact
    21181 ctcataacaa aaaccaaagg atttaccaga cagattaagc cgaataaaag gcttattttc
    21241 tagggtgaaa cttggctcag tattgtaaag attcagttcc tgactgagtt ctgcaaaata
    21301 atccgtcgca gcctgaggac tttttttctg atagagttct gcaaagtagg cattaacaac
    21361 acttggcgga ggtgtaataa gtgttaactg ctcctgctct gttttaccag ctagaagctg
    21421 atccagatag accttgtcca gacttgtata acctccatac tttagagcca aagttttaat
    21481 atcagtcata aaattcttct aacctccatt tatttttctc ggaaatgtag cctgtaatca
    21541 cttcgccgtc ttcctgataa tcacgttctt ccagaattgc aacactctct aaatcatgaa
    21601 tcttgtagga ctttgaaaaa ggcactcgca gggtaaatgc ttcaaaaatt tccttaatct
    21661 tatctagcaa taatgcttgc aagttttcac gactgtcctc agacttggca gaaatgaggg
    21721 tatatggcgt ttgggtaggc gtgaaatcct ccaccaaatc cgctttatta taaagcgtca
    21781 agtgaggaat atcttccatg tccaggtctt tcatgatgga gagaaccgtt ttttcatgct
    21841 cctcgtggta aggattgcta gcatcgataa catgaaccag aaggtccaca tgcttgcttt
    21901 cttccaaggt tgacttgaaa ctggacacca actctgtcgg caaatcttgg ataaagccaa
    21961 cggtatctgt caaagttact tggagattgc ctcccagatg aatactcttg gttgtcgcat
    22021 ccagagtcgc aaagagctca tctgcttcat actgggtctt actggtcaag atgttcatga
    22081 tagttgattt cccagcatta gtataaccaa tcaaaccaat cttaaaagtg ctagactcca
    22141 aacgtttttc tctgacagtc gcccgatttt tctcaaccac cttgagctgg cgctcaatat
    22201 ccgtgatttg attgcgaacg ctacgacggt tcagctccag ctggctttca ccaggaccac
    22261 gggaaccaat tccccctgcc tgacggctga gcataatccc ctgaccaacc aagcgaggca
    22321 aaaggtattt gagttgggct aggtggactt ggagcttccc ttcatggctt cgagcccgca
    22381 tggcaaagat atccaaaatc aactgcatac ggtcaatgac cttaacaccg agaacttcct
    22441 ctagattgac attctgcctt ggggtcagac ggttgttgac gatgacagta gtgatttctt
    22501 ctgcatccac cataagcgca atctcttcca acttaccaga gccgacgaag gtcttggaat
    22561 catatttttc acgtttttgt ctgtagctat ctacaacgac tgcccctgcc gttttcgcta
    22621 aactagccaa ttcttccatg gagaggtcaa aactgtccat accctgcaat tccacaccaa
    22681 tcagcaggac tcgctcctct tttttctccg tttcaatcat ctaaaaactc ctctatctgg
    22741 cttaaaatgc ggtcttgtac accagattct ccaatctgat aaaaggtgac ctgcatgcga
    22801 ttacggaacc aggtcagctg acgcttggca aaacgacggg tcgcctgttt gagactctca
    22861 ctagcttcct ccaaggtctg ctctccacgg aaataaggaa agagttcctt atagccaatt
    22921 cctttagcag cctgtacatt aggggaatgg tcaaacagcc acttggcctc atccaaaagc
    22981 ccagcctcaa acatcaaatc cactcggtgg ttgatacgct cataaagttg actacgttca
    23041 tcatccaagc agataatcag cggttcatac aaggtctctt gattttccaa atcctgacca
    23101 aaatgggcaa tttctaaggc acgcatagca cgacgacgat taaactgggg aatctcaagg
    23161 cctgcttgat ccaccaaatg ggctaattcc tcatctgaat atggctccaa actagctcga
    23221 taagctaaaa tctcctcatg aggagtctcc ccacctaggt ggtaaccttc tagcaagctc
    23281 tggatataaa gtccagtccc accggcgata atggctagct tgccacggtt gtgaataccc
    23341 tcaatagtca tcttagcttc tgaaacaaaa tcaaaagccg agtaagactc ggttatctct
    23401 ctaacatcga ttaaatgatg aggaacagct gcctgctctt ctggactagc cttggccgtc
    23461 ccaatatcaa gtcctcgata gacttgctgg ctatctccac taaccacttc gccattaaaa
    23521 cgctttgcaa cttcaatagc tagagccgtc tttccaacag cagtcggtcc aacaatcaca
    23581 attatttttg ttttcatctt ttttccttga aaaattccca ttttttcgtt actattatta
    23641 taacacaaaa aggtcagtca gaaaaatgtg acctcttgag gaggctggct gattgagaat
    23701 ataaaggagg aagactcatg gctaaaggat tcgctaaagg tcttgtaaca ggtgtcgcag
    23761 gaactgtcgc tgccgttgca ggtgcagtat acgcatttaa aaagaaagta atcgaaccag
    23821 aagagcaaaa agcagctttc atcgaagaaa accgtaaaaa agcagctcgt cgccgcgtat
    23881 cacgttaaga aacaaaagaa gttgggatta ttctcaactt cttttttcta ttcttttaaa
    23941 tagctaggtc aaacttcaac tgtggcttaa cagggtcata atccaccaac tcaaaatctt
    24001 ctgctttgat atcaaagaaa ttagtcccat caggaacatt taaaaccaag cgtggttggc
    24061 agtttgacgg ctcccgacgg agcaattcct gagcttgttc aaattgatta tcatagatat
    24121 ggaggttgtt gatgaagtag aagaacttcc caaccttcca gccaaaatgt ttggcaatca
    24181 tcatctgcaa agccacatac tgcatagcgt tgatgtggtg ggccaccagc atatcattcg
    24241 agcgctgggt caaggtcgca tccagataga tttctccatc tatacggcgg acatcaaaca
    24301 tggtctgaaa ggcgcacggg agcagcccat ctgtttcttc gaaagcttgg taatcccaga
    24361 gcgaaataat attgcggcgg ttccaaggat tggtttccaa ctgtttgaga agcttattga
    24421 taatgtcgtg tttcttaaca acggcaccat agcgctcacc aatggttccc gtgtctccaa
    24481 cttcccagtc attccagtag tgaacattgt acttgtcatt aagcacttct aagctatttg
    24541 actggtcttg gtaaatccag agaacttctt tgatggcgga tttgatggca atgggacgca
    24601 aggttgtgat aggaaattct cctttagata agtcgtactc ggaaaaggca ccagttacat
    24661 acttggaatt agcaacagtc ccatccttgt acttaggacg agcctgctct gagaaaacac
    24721 cttcctttag aatgcgttca atattctctt taaaaatcgt atctgctttt gtcatttact
    24781 ctcacctcat tcattgtcct aactagtata gcataaaaaa taaaagagga acattactaa
    24841 ctctaggtta gcattttcct ctctcattat cttattgcaa tacaagtgat gctgctccga
    24901 taactccagc gtcatttcct agagttgcaa gagctaattt agtagatgtg cgtacttgtg
    24961 ggaaactatt ttcatcgtaa actttttgaa caccttgtag aaggaattct cccgcagctg
    25021 acacaccacc accgatgacg attgttgatg ggtttaggat tgaaccaatg ttagcacaag
    25081 cgattcccaa gtaacgtgag aagttacgat aaacaatcaa agcaaggtcg tctccttctt
    25141 ttgcgagatc aaagacagtc ttagcagtta cttcttctcc gttatcaatc aagcgtttca
    25201 aggctgcatc gccttcgtat tcatcggcat agcgacgagt caagttgaca atccctgttg
    25261 ctgaagcaac tgtctcaagg cagccttttt taccacaagt acatgagatt ggttggtcaa
    25321 agtcaacagt gatatgacca agttcacctg ctgcaccagc aacaccatga agcaatttgc
    25381 cttctgcgac aataccacca ccaacaccag taccgagtgt cataaagaca acgtctggtt
    25441 ggttatctcc agcacccatc cagcgctcac caagagctgc tacgttggca tcattatcga
    25501 tgaaaaatgg aatgcccaaa gctttttcaa tcttttgttt gattggttga agggttttcc
    25561 agttcaagtt gtaggcaccg ataacagtcc ctttgtcacg gtcaaccaca cctggtgatc
    25621 ccattccaat gccttggaag tccgctgctg ccaatccaag caagtccaaa cgatgttgaa
    25681 tagactcaat catatcatca acgatatgac ttccctcatc caaaatgttg gtcttgattg
    25741 accattttcc ttggatttct cctgctgttg ttaagattgc aaatttgata gaagttccac
    25801 caaggtcaat cccaataatc ttttgactca tcatattctc ctttttcatt gtgtagtaat
    25861 tgaaaatgct tacagtacta gtatatcaaa atccattcac ttatgcaaag gtttgcgtaa
    25921 atgaattata aggaattttt tcgcctacca gtatctgtta atcatctaaa tgatcaatgg
    25981 catattgagc tgcatcattt gaaaatttat caaaatcaga agttaattgt ctatacatac
    26041 gtttttttga catgtggaat aacgaattat aactttttgc ctttcctaaa gcagcagaat
    26101 attcactatt gctatcatta ctagaagaaa ctgtacttgc ttgaccttcc ttccaaactc
    26161 cgtcagcgcc aacataataa cgtccaccat caacccattc attgacagcc attttaccat
    26221 ccgattttag atagtaattt ccttgccatg tactgtaagc ataagaacca tctgatgtca
    26281 aataatacca agcttgatag gtggcatcat aaacccattc acctttagcc attttaccat
    26341 ctgatttcaa atagtagttt ccttgccatg cattgcgagc atatgaacca tctgatttca
    26401 agtaatacca tgcttggtaa gaagaatcat aaacccactc accttgtgcc attttaccgt
    26461 ttgatttaag gtaataagct ccttgccatg cattttttgc ataagaacca tctgatttca
    26521 aataatacca agcttgataa gaagagtcat aaatccattc actctgtgcc attttaccat
    26581 cagctttcag gtaatagctt ccctgccata catttttcac tagatttcca tttccatcaa
    26641 agtagtacca agcgccgtcc tgcttaaccc aaccacttgt tgttgctgaa cttgtgttga
    26701 tttgaatagc cgttgactgt tttgctttaa aagcaccctt aggagcattt ttcaattcgc
    26761 aagccacacc atcatgatca cggtctaact tggcagaata accaggttct ctctcgtgaa
    26821 tatccgaata gccattcgcc caagcttcct tacagctcga aaaatggatg ttttcttccg
    26881 ccaaaactgg ttgtgaaaac aaggctaaaa ttggcaacgt caccagactc atttttaaaa
    26941 atagacgttt attcatttct ttctcccata attatgatat cgatttcaat attattttat
    27001 caaacttatt tcagcaattc aaggaaactt ctggtctttt ctacaaactc ctttggtttt
    27061 gccttattca agacatgagg gccatcagga atgatctgaa actgcgaatc tgttaacagt
    27121 ctatggagag ctttcataaa actaagattc ggtttatctt tgctgccaca aattagtaag
    27181 gttggatagg agcaagtccc tgctatatcc gttaaatcaa gtgtcttcaa ttcctcagaa
    27241 actccgacca taagagtctt gtctgctccc tgtttttcaa atactctttt gggaagtagt
    27301 ttaaaaatca gcaactgaag ataaaatagg atattccctg ctaatttaag cgggcatcct
    27361 gacagaatca aagctcgaag atttggtaaa tcgtaactgg aaagttctag tgtcagggca
    27421 gcacctaagg acaatccaat caaaacaaaa ggttctgtct cttgagctag gtgctgataa
    27481 actcgctctt tagcttgttg atagttacta actccagaag gaaataactc gatagcctca
    27541 gaaggataat ctgtcagtag attccgaact tctttccaag actctgctga ctgccctaac
    27601 ccatgcaaaa atatcaattt catctagttc tcctcaaggc ttagttcata caagcctctc
    27661 actgcattac agccgtaaat agcttctgct tgggttaaat ctgccaaggt caagactttc
    27721 tcttctacct gtcctgtttc tagcaaatgc tgacggtaaa ttcctggcaa gattccaagt
    27781 cggataggcg gtgtgtagag ttttccagcg attttcagaa ccaaatttcc tatagaggtt
    27841 tcaagcagtt ctcctgactt attgtggtaa atcttctctt gttctcctag gctcaaatgc
    27901 ggtcggtgag tggttttaaa gtaggtaaag gattgattca aagcagcttc ctgaaggcag
    27961 acttgggcct gacaaaagct tgtactgaga ggggttaata cttgacgatt gacttctatc
    28021 tctccagatt tgctaaggct gattcgcaag cggtaatctt gattagcttc acaatcctga
    28081 cactcttcct caatcttgtg tcccaagtct tctgcatcaa aaggaaaggc aaaataacga
    28141 ctagcttttc tcagtctttc cagatgttga tcttcaaaca gcaggttctt ctggctgatt
    28201 tcccctgtcg taatcagttg gaagcgagct tgtttacgat aaagaactgc tgccttttga
    28261 tgaacctctc ggtattcaga ttcccatgtg ctatcccaag taatccctcc gccaactcca
    28321 taaatggctt gacctttgtg aagttgaatg gtacgaatgg ccacattaaa aatccgtcgt
    28381 ccatttggaa gcaagagacc aatcgttcca cagtagactc cacgcggttg aggctccaag
    28441 ttcttgataa tctccattgt cgcaattttc ggtgcacccg ttatggaacc acaaggaaag
    28501 agtgagcgga agatttcaac aaggtccaca tcctctcgca actgactctt gatggtcgaa
    28561 gtcatctgcc aaacagttga atactgctct acctggcaca gacgctccac gtgctcgctc
    28621 ccaacttcag aaatacggtt catatcattg cgcaagaggt ccacaatcat catattttca
    28681 gagcgatttt tgggatcctg ttccaaccaa ctggcctgtt caagatcttc ttggtcagtt
    28741 accccacgct gagtcgtccc cttcattggt cgtgttgtca actcgcgatc attttgctca
    28801 aaaaagagct ctgggctcat ggaaatcact gccatctcgt catgttccac ataggcattg
    28861 tagcccgcct cctgctctac caccatacga ttgtagatgg caaaaggatt ggcacttaac
    28921 ttttgcttga gttggacggt gtagttgacc tgataggtgt ctccctgcct caagtgatgg
    28981 tgtatctggg caatggcctt ttcatagtct gctgcagacg ttacttcctg ccaatttgag
    29041 ggcaaatcaa tatcctcata agtcagagga ataggggaag tttctacgct atcatgaaca
    29101 gtaaaataaa gcaggtactc tcccagtagg ggatccttgt gaactgctaa tttttcctca
    29161 aaagcaggtg cagcctcgta gctgacatac cccaccacat aataaccttg ctcttggtag
    29221 ctttccactt gtgccagcaa atctgccact tcttctacat ttctcgtttt caactcttta
    29281 ataggctggg taaaggtata tctctcccct aaagtcctaa aatcaatcac tgtttttcta
    29341 tgcatacctt aagtatagca taaaataaga aaaccctcat ccgcaaagca gatgagagat
    29401 ttcgattatc taaagataga agttttaaag ctatctgttt gttgaagaag ttgtctgaaa
    29461 acttggaatt tgaagtttct tgtttccctc tcatctaact gatttttctt caaatctctt
    29521 tcaacagcct gcttaaatcc ttcttgcaat tcttcaaagg tgctatatgt tttttgattg
    29581 atagtaacag gacgaatacc tttagttttt aactcttcta ctactttctt aaaatatccc
    29641 tttttaaatg cttccatagt taaaaattcc cctttggaaa tcttagaaat aataaagtta
    29701 tcactaagtc cagcatgacc ttcatctcta gatgcttgct taaatttatt agaagcatat
    29761 cctagaacac cttcttcaaa accatagtag ccccacatac ggaaagtatt atgtttaaac
    29821 atcaaggcac ctggtgaacc tacactattc tttcctccac cataaatacc agtcatataa
    29881 tctatcgcaa tataacttgt ttcaaaatca gctggattat aggtattatt tcctacagct
    29941 ctgtctgaca ttaatccttg atcaactaaa tcatcaacac tagaaacaga aagtttttct
    30001 ttctcttcag cagtcaactg acgaaccgta tcatactgag ctgtttgact aacaacctta
    30061 ggttcaactt ttttaaacca tttagtaata gcttctttac ctttagagat aactgcatct
    30121 ccttccaagt agtccaccat catgagagta tcgttataat ttttcatata actatctaac
    30181 tctttcctat tttcaaattg agttggggag gcattataaa ttagatcacc atcatttttt
    30241 ctttcaaatg ccatattgag accaagcgcc ccccaacccg gctgacctgg aacaggagac
    30301 tggaataatc cctgagcata agcttcaggt cccatatttt cacgtctacc ataccctcct
    30361 aagtaaatcc aagtatcatt aacgtgagtc aattcatgag taaagaccga tataccatac
    30421 tcacttaata catcaaacac ctcataatta acccgatttc ttcctccagc atgcgcacca
    30481 taaccatggt aagcatacca acctcccata ggaccaccta caagattaaa gaattctcga
    30541 gctggggcgt aatctcttcc ttttctatct acagcattct ggtctaccca ttcacttcct
    30601 gggatgctca atccttccca aacagcagta acattctctt taaccatttt acctttgata
    30661 ttatcaggta aaatcttata ccaagtatca acatggtttc tatgagcagt tgctacatat
    30721 ttcacccact tatcaaaatc ttcatttttc caattagggc gtttttcacg gctgacaaat
    30781 gtcatagtac tatagttcga taaaattgct aaatgagtat tcttcaacgt taagagaggt
    30841 aggatatatc cttgataata cggtgcggtt aaattatcgt aaactcgata tttggcatct
    30901 ttaatctcct ctactaagga tggacgttcc tcaaattgaa tataatcctt agtcgtttct
    30961 ttaaaccatt cccctgttgt ttgataatta gtcaacaaag agcgattgta gtctaaataa
    31021 gtcaccaaat ccttctgctt cgtttcgcta gcaaataact gcttgaacgt ttctgcattt
    31081 tctgaacctt ttaatctatt ttctccagat gatcctagtc ggattaatcg atctaataga
    31141 tcaatctttt caccatggaa agttggttta aagagcatca gttttttaat attatagtct
    31201 gagaatttaa catcataata acgattgata taagtcaaag caagcaatat agccgtctta
    31261 ttatccatga ttttttgtcg taaagcagcg acagctccac tagattctcc attgatgtgc
    31321 aaccactcat tttcaaacat tgtttttaca aaggtaggca attgtgtttt aacagcatct
    31381 aatgactcat ctaagaataa tctcttagtt ctattcaatt tgttagcatt atctttatca
    31441 atacctagaa cttggtaagt agactctgta tacaattcta cttttttcaa ttcttcaaca
    31501 aggttattta tcagtgacga atctagtgga tgtactatat gttctgatgt atacaccaca
    31561 tttaaatctt caacctgata ttccggtaaa ttagttatcg aaaacttacc agtagaggtt
    31621 accttatatc gcttctgact accatcctca aaatgaagca tgatagtatc aatatcactg
    31681 ccatctacaa cgaactctgt tcctttcaac cctacaatcg atttgatttt cttagtcttc
    31741 aatatttcct gttcaggagt gagagcattt ccttcatgaa caataaattc tttattgtaa
    31801 taaggagtaa atttagtcaa gttctggtaa attaattggt tttgggattg ataatcctgt
    31861 atactttcaa attgatcagt atttttccaa ctttcattga gtctgtctac caaaagactt
    31921 gagtcgctca tcaagttggg agctgtaata ttataagagg caaccttttg ctttgcttct
    31981 tcctcggaaa tacgcttaaa cttagaatca ttccctgagt cacctgagct gataccttga
    32041 acaccaaaaa tattattaat tttttgcata aaccaattat tatttaaatc accatctgac
    32101 ccaaataatt cttttccttt ggtaactttt gcatagctga caaccttatc aattgctcca
    32161 taaggccaga ctgttgcagt aactccacca gcttgtccac tgcgtttaat ttctaacgtc
    32221 cctttagcaa cggactcagt aagtcttccc caggctcccc aacctccact agcattcaat
    32281 gttgtaccat ttactgcaac aagcatactc gaattcgttg aaccaaggac ttcaatattt
    32341 gcatttacat aggcacgttt aacacgagat aagatatttc tacctgcaat acctgctgta
    32401 atagaattac cacctttaga cttaatcttt cctgtaaagg atatattttc aatttcggaa
    32461 ttaccttcaa gattattaac taaaccagct acatgatctc gaccctcgag ataaccttca
    32521 acattaacat tctcaatttt tgtcttatct ttgattactc ttgcaattgt tgctacgtta
    32581 tctccttgat tgctatctgg gaataccata ttgacatgct tgaaatcaat atctttcacg
    32641 actcctgatt ttatagtatc aaacaatgga tattctaagt caaagatcga gtgtctaaca
    32701 ttatcatttg taccaagtag ttttccttta aattcacctt tgatataaga ttttccattt
    32761 ccatccggtt ttacattacg cgaggaaata tctctcccta aaataaacgt acctgtagga
    32821 ttagatgtca tagctgaaat caagtcttta aaatcataat aaatatcacc atcatgaggg
    32881 ataactctct ccatgtaata gtcaaatccc ttagaaagac tgccatcttt cttacgaact
    32941 actaattctg gtgtatctgc atgaatttta aagatttttt tattttcaac aatctcttct
    33001 tctatagagc taacggctaa cacagcatcc ttagacgttg atgatgtaac ttttaagtat
    33061 aatttactca aatcggtcgg tttatcagac aagtgtgtaa cctgactttc ttgaccattt
    33121 tcaaatttca tcagagagac tgtctggata tctttcaatt ctagtttctt aagattcagc
    33181 tgaattagtt cttctgaaat actctccgtc tcatcatcat ttcctctgtt atataccata
    33241 tccgtagata gagtgtattc tttgtagtaa tctagctttt caaacaaagc agttaaatga
    33301 ttagttttaa gattttcttc tgttaaaaca aaatccttaa caacttcctc tccttttttc
    33361 agagttgcag ttattgattt tatttgagta tttgctggat tttccaaagt atacgtgacc
    33421 gtaacttttc gatctatgtc tctcttttca atagatagag tcaaacgtgg cttttcagac
    33481 aattcaacca atttttcaat agttgcagtt aatttttcaa cagcttcatt aacttcactt
    33541 tgtttagact cgttagtgtt tacagatttt gctgctgtaa gaactgtttc taactctgcc
    33601 catgtttgat ttgtatagtt ctctttattt ttcttggtag ctgtatcgat agcgcttccc
    33661 aaagctgttt tgtcaacaga taagtcagca agggctgttt tcaaactttt ctctgcttcg
    33721 tttatttgtt cttgggtcgc tgttccgtta tcttttactt cctgagcttt atttttagct
    33781 gtactcaaaa ccgtccaaga ttccatgctg aaatcagttt cagtttttcc ctgtgcaatc
    33841 ttaagttgat tttcgagttc aactttatct gtatttaatc cagaaattgc tgttttaaga
    33901 cttgcagtct cagaatttac ttcactttgt ttagcatctg tattagctgc aactttttca
    33961 gcttttgtct cgctatttac ctcaggctgt tttacaggct ctgaagcata gacacctttt
    34021 gcagtttcta aaacaggtcc aagagcattg taacttgctg tagaataatc agtaggagaa
    34081 actgaactag ctttatcaat ttgattattt aactcacttt tatcaactgg ttctttagta
    34141 ccaataccct ttattttatc ttcttgtttc ggtgtttctt ccgcagtctt ctcttcttca
    34201 ggagcttctg gttgcttttc tggagagact ggtgcctttt cgtcttctct tggctcgact
    34261 ggttcaccta cttgttcaac ttttggttcc tctgttggtt ccgtttgttt ttctacagca
    34321 ggcgtttcaa cttttggttc ttcaacaggt tgattagcag cctcatcttt tgtttctact
    34381 acttctggct gtgtatcttc ttgtttcggt gtttcctcta cagccttctc ttcttcagga
    34441 gcttctggtt gcttttctgg ctcgactggt gccttttcgt cttctcttgg cgcgactggt
    34501 tcacctgctt gttcaacttt tgattcctca gctggtttgt ctgatggttg actttctggc
    34561 ttaactgcta ctttttcctc tgattttgac tcaacttctc cacctacttc ttcaactgga
    34621 gctggttctg ctgaatcttc tttcccctct tctactttag gaagggtgtc gtcagtaggt
    34681 tttacctccg attttggttc ttcctttgga ctttcttctg ttttaggtgc ttcttctttt
    34741 ggagcttcct ctgtctctac tacttggttt tctgtcctag cttgctcctg atttgttgtt
    34801 gattgaggag tctcaacttc gactacagtc acctctccag gttttgctga ggtttcttct
    34861 aaaacagtgt ccaagccaag cgttttgagg atgtcacctg atagataacc aacatagcga
    34921 tagccatcca tttcaacaac accctctcga ctagccagcg ctagggtcgc aactgggtct
    34981 acagcctctg cactaggaag aactaccaat cccatagctc caactagaaa gacgctagca
    35041 attttctttc tcttgtagat taaaagcaag ctcccaacag tcagcaaacc aaaagctgtc
    35101 aaaacagatg cttctgtccc tgtttgaggc aactgatctt tttgatacac caaaccatat
    35161 acaacttcat tcctgtcagg ctttcctgtc tgaattaaat ctttagcttc ttgtgaaata
    35221 atctctttat ttacatagtg ataggtggct gcgtccacta cagaaggagc catcaaaagg
    35281 cttccaagaa atacagagcc tacaactccc ttaatcttac gaattgaaaa acggtctttt
    35341 ttaaacactt ttatctcctt tattcattct caagactttc taatagcgtc ttgcggatag
    35401 tgcgcacgcg cacctccgat taattttgga cgactagcca gtgccgttac atgggcatga
    35461 ccaatctctc tcaaaatagg gcgaatcgga acctgaacat gcttgacatg catgccaatt
    35521 gcagtgtctc cgatatccaa tccagcatga gccttgataa attcaacctc aactggatcc
    35581 tgcataaact taaaggctgc caactgcccc gaacctcctg catgaagagt aggatggaca
    35641 ctgacaattt ccagatcaaa ctgctctgcc acctgacgtt caacaacgag agcccgattg
    35701 acatgctcac aaccttgaac tgctaaatgg atacctctac tacctagaat acccaagata
    35761 gtctccacta tcagctcacc aatctcttga ctggattctt tcccaatctg accacctagc
    35821 acctcactag aagatagacc taaaacaaaa aggaccccct gcttcaaatt ggtcttttct
    35881 aaaacatctt ccactacctg acgtgtttct ctttgaatct gtgtctcgtt catctctgtt
    35941 acctctgttg tcactcttct atcataccgt tttttcttgt ttttagcaag atagacaacc
    36001 tataaagttt gcccaattac gcataaaact cccagaattg actgggagtt agctagtttc
    36061 tattctattt atatatattt caactttcgt ccctttttgg ggtctagaat caatcttcat
    36121 ctggtaattg gctccaaaat gaagtttgag ccgttgatcg acattttgaa gaccaactcc
    36181 cccacgtttg agttgacttt gactactatc accagcatct tggaagccaa cgccatcatc
    36241 ctcaatacgg atgaccaatc ccgaatcctg tttctggaca gaaagtttaa tatggccctg
    36301 accttccttt tccttaatgc catggtaaag agcattttct acaaggggtt gtaggaccag
    36361 cttgggtaag actaaattat caaaggcaac attttcatta atttcgtatt ccagcttatc
    36421 tccatagcgt tgtttctgga taaagagata ctggcggaca tgattgattt cgtcagagag
    36481 acaaatcaag tccttgcctt gattgagcgc caagcggaaa taggttgcca aggacttggt
    36541 cacctgcacc actcgctgac tatcatgaaa ttcagccatc cagatgatgg tgtccaaagt
    36601 gttatagagg aaatgtggat taatctggct cgaaagggct tgaagttggt actgacgggt
    36661 cgtttcttcc tggctacgaa tagctaccat caactgatca atctgatcca acatggcatt
    36721 aaattggcga gttacttctc tcagttcata ggcaccaact tccttggcac gaagattttg
    36781 agcaccagaa gcaatttcca acatggtttc tctcaaatcc ttcaaaggag caatccagcg
    36841 tttaagactg aaccacacta agcagagaca gacaagaaga gatgtgacac tggccccaag
    36901 caaggtccac aagagctgac tccgaacctg gtctaacttt tccaatgatg acacgccaag
    36961 taccgtccaa tcagttcctg caatcttctc ttgactgacg taggatttgt gaccaggagt
    37021 ataaccctga cctgtctcga tgtagggttt catagcctcc attttgctag acgaactata
    37081 aactgtgtgt tgaggatggt agacaaattc atggttttca ttgataatga aggcaaagcc
    37141 ctgctgcccc aactggagtt gattgagata ggcttccaga gtttcataag aaatatccaa
    37201 acgaagcaca ccaagattgg ctccctttgc atcaacaagt tcttgagtga cagaaatgac
    37261 ccactgacta tctgatttac gagctggagt caaaacaggc atagctccct gatgaatagc
    37321 cttttggtac caatcctcag ccatcatatc agaggaagtt ttcatctgca cactgtcatc
    37381 tgtagaaatg acctgaccag atttggtcac cagcacaaca gttttcaagt ccttatctga
    37441 cttcaagatg gtcaaaaaca aatctcggat tccctcgacc ttgtcttgac tgggattctc
    37501 agcataggcc agaacatccg tctgctgggt caaaccagtc gaggtggttt ctagtttttt
    37561 gatataagac tgaataaagt ggctagtctg gctgatggtc gtttggctgt tgccctcaat
    37621 ggtggcctca atggctgaag aacttgattg atagtagaaa gttccaacca gagctaggag
    37681 aatgagaaag accagaaaga tggaaataac cattctaact aaaagagaag aacgcttcat
    37741 cggtcttctc ccttcttaaa ctgacgaggt gtcacacctg caatctgctt aaaacgttgg
    37801 gtaaaatagt tcatatcttc aaaaccaacc ttctctgcga tctcataaat cttcagatct
    37861 gtagttaaaa gcaagagctt ggcttgttta acacgttctc tcaccagata atcctgaaaa
    37921 ggcaagccca actctttctt aatcaaggaa ctcagatagg tcggactaaa acctaagtca
    37981 ctggctaaag actttaaact aaattggcta tcagccagat gagactggat tttctgggcc
    38041 atgtttcctt caaacctatt agtcaataaa tcttgtaact gctcttcttt ctcttccttg
    38101 tctagttttt gtttgatttt ccccaacatt tcctcaatat cctgacgaga aaagggtttg
    38161 agcaggtagt cgtccacacc tagtttgaca gcagacaagg cataatcaaa atcatcgtaa
    38221 cctgttaaaa agaccaaatg aacctgagga taggtttctc gtaccagact ggccaactgg
    38281 atgccattta gatgaggcat gttgatatcg gttaaaatga tatctggcac ctgcttttgg
    38341 atcaattccc aagcctgcct tccattttca gcctgaccga tgatttccat atcgtaggct
    38401 gctacattga ccagtttagt caaaccttgt cttaccagat attcatcttc tacgattaag
    38461 attgtgtagg tcatgatctg ctcctttacc acttactagt atcagtatag caaaattctc
    38521 ctctaactgc ttaggaaaga cctcttatac tcaataaaaa tcaaaaagta aactaggaag
    38581 atagccacag gtttctcaaa gtaccgcttt gaggttgtag ataaaactga cgaagtcagc
    38641 tcaaagtata gctttgaggt tgtagataaa actgacgaag tcagctcaaa gtatagcttt
    38701 gaggctgtag ataaaactga cgaagtcagc tcaaagtata gctttgaggc tgtagataaa
    38761 actgacgaag tcagtaaccc tacatacggt aaggcgacgc tgacgtggtt tgaagagatt
    38821 ttcgaagagt attaatcaac ataatctagt aaataagcgt agcctttttc ttccatttgg
    38881 tctttgggaa taaagcggat agagaggcta ttgatacagt aacgtaagcc gcccttgtcc
    38941 tgtggaccat ccgtaaagac atggccaagg tgagaatctc ctactcggct ccgcacttcc
    39001 atacgcgtca tattgtagga cttatcttcc ttgtaggtga caacatctgg actgatgggt
    39061 tgggtaaaac taggccagcc acaaccagac tcaaacttgt cctttgatga aaagagaggt
    39121 tctccagttg ctatatccac atagataccg gattcaaatt tatcccagta acggtttgag
    39181 aaagctcgtt ctgtttgatt ttcctgggta actgcatact cctcaggtga cagggtcttt
    39241 ttcaattcct catcacttgg ttttggatat ttgctggcat caatgacagg ataggccgcc
    39301 tgattaacat tgatatggca gtagccattt ggatttttct tgagatagtc ttgatggtaa
    39361 tcctcagcca ccacaaaatt cttcaagttt tccttttcaa ctgctagagg ttgatcgtat
    39421 ttcttagcca cctcatcaaa gacttggtta atcacttcca aatccttgtc atctgtgtaa
    39481 taaacaccag tacggtactg ggtccccaca tcatttcctt gtttattttt gctggttgga
    39541 ttgataatgc ggaaatagtg aagcaggatt tccttgagag aaatttgctt ggcatcatag
    39601 gtgacatgga cggtttctgc atgacctgtt tggttaatca attcgtactt ggttgtttct
    39661 cctctaccat ttgcatagcc tgaaacggca tccgtcaccc cgggaacgcg tgagaaatat
    39721 tcctccactc cccagaaaca acctccagct agataaattt cgtgcaagtc tgcgtcttta
    39781 ctaatttctg tttttttcac tgcttttcct ccttggctaa ctgccgcctt ttcaatttgc
    39841 gaggcatctg tctgccctgc atttcgtatc aatagaacat agaaaccggt tatggctaga
    39901 aaaaatactc ctagcaacaa gaagattttt aacttatcat tcataagacg cctcctaggc
    39961 taattccttc aaagtttgca aaattgcatc tttttccatg aatcctggat gtgttttgac
    40021 cagcttgcct tctttgtcta taaaggcttg ggttgggtaa gaacggacac cataagtttc
    40081 caaaagtttg cctgatgggt caactagaac tgggagattt ttataatcca atcccttata
    40141 ccaattctta aagtccgctt cagattgctc tcccttatgt cctggtgaca ctactgtcaa
    40201 gaccacatag tcatcaccag cttctttagc aatttcatcc gtatctggaa gactagccag
    40261 acagatagaa caccaagaag cccagaattt gagatagact ttcttgccct tgtaatcaga
    40321 taaacggtag gtcttgccat ctactcccat caattcaaaa tcagccacct ctttcccttt
    40381 agctgcgctt gttttactag ctgtctgctc cgtcttcatt tcatctttcg tttggtgttc
    40441 actagtcacg gacttgcctg aacaagccgt caaacaaagg agcgaacctg ctccaagaac
    40501 acatgtttgc cattttttca tattgatatt cctttccatt ttattcaaat aattgactta
    40561 aaattgaagc atttccaaac agaaccaaga atcccatcac aataatgaga aaaccaccca
    40621 cttttttgag gattccgaga tagggatgaa gttttcggaa atgtttcaaa acataactag
    40681 aggtcagagc tagaagcaag aatggtagcg ccaagcccag cgtatacacc aacatgagac
    40741 cagctccctg ccaagctcct gaaccacctg aagccgccaa ggccaaaaca gaccccagaa
    40801 ccggccccac gcaaggcgtc caagcaaaac taaaggtcaa gcccaataaa aatgcctgac
    40861 tatagccctt accattttgc ccctgtcctt gcagttgtag cctcttttcc ttataaagcc
    40921 ccttaaagtg tagaatctcc atttggtgca aaccaagaag gataataatt gccccagtaa
    40981 gatattggaa ccaagaagca taaagcaaat cgcctaaaaa accagctcca tagcccaaca
    41041 aaataaatat aaaggaaatt cctgctataa aggccagagt tcgtaataaa ctagtaactg
    41101 agattgaaaa tttgccgcta gaagcctgag caccatcctt atcatctagt aacactcctg
    41161 tatagaccgg taacaaaggt aagatacaag gagaaaagaa ggatagaatc cctgccaaaa
    41221 agacacttag aaaaaagaaa atatgaccca taaagttcct cctatcattt tattgataga
    41281 tttattatac tccttccatt ttcgaaaaaa cagggacaat gataggggaa aataggaatt
    41341 taatcagatg atttagaaat cttggacaaa aactatacaa aaaactgtca aagcacaaaa
    41401 gcgcatagta tcaaggcttt atagaatctt gatactatgc gcttttgtaa tggataaata
    41461 gttagtcttt tttaaagacc ggatctttca aactctgcat actggcattg atcaccgcgc
    41521 ctaggataac aattttagca atcaagataa accaaaacat cataacaaca agaagaacgg
    41581 aacctaaaat tcggacatcc accaaatgat ggacatagta attgagataa ctagagaaca
    41641 gagttagtaa acctaaaatc actaagagaa caaaggcact gcctggtagg gtatagctaa
    41701 ttttcctgtt agatagattg ggaagaaaat aataaagcat gaccaagata gcaaagagga
    41761 gggcgtaaat cagaggacct gccaaccctt gtaaagcctg atagataatg ccatcttttg
    41821 tccaataatg agcaagtaaa gccaaaatca tctgaccaaa taagatcaaa aacaaggcaa
    41881 acgcaaagag gagctgcaag ccaaaactga ctaggagact tagcatctga tgggaaataa
    41941 gtccacgact cttttcgacg ccataagcct tgttaaaagc tttttgcaag aaattcatag
    42001 attttgaaaa actccataac gccgataaaa cagaaaaact caataaacct gttgaaggtt
    42061 gcgtcaagac ttctctggct attttttcca caccttcata gaggcttggg ggcaggacgt
    42121 ctttcataaa gcccaaaaat tctcccacag gaatctgaaa ataggggagg atattgacca
    42181 ccaccaaaag cagggggaaa atcgaaatca accaatagta ggctactgcg acactggtca
    42241 actcactatc tgatgcttga taataatgca aaaaagcttt taataaaggt ttgtctatca
    42301 gctctttcca ccactttttc atgtcatact ccttcattta taatcttata ctcaatgaaa
    42361 atcaaagagc aaactagaaa gctagccgca agctgctcaa aacactgttt tgaggttgta
    42421 gataagactg acgaagtcag tcacatacat acggtaaggc gacgctgacg tggtttgaag
    42481 agattttcga agagtattaa ctaatttctt cttaccaatt ccaccatatc atacggtagg
    42541 gtattggcag cttccttcaa ggaatagttc tctaagttat ttacattttg tcgtaatttc
    42601 ttggcatact tagtcgtaat caatcgtttt tcttcgtatt cgaaaatcaa cttgcgctcc
    42661 agataatagc ctctcagcat ttcatcgata ttgttgggtt tgacacgatt gataacccgt
    42721 tcgacaaagg caccactgct gataatagct gtttctcgaa gacgagactc ctgcataaaa
    42781 ctaatcaaag agcgtctgta gactcccttc aggttttcca aactttcaat aatcatctct
    42841 gtattggcaa gatagagctc tgcaatttgg tcataatcaa gagcacggag acggctttgc
    42901 tccttgttct tccagctacg gaaggtcttt ccgagagtaa aaacttcatg aaggagaaaa
    42961 cgtaaaatcc gcaaagaaac aaggaaataa taggtcagtc ttgaggcaag tttacgattg
    43021 attccttgtt ctatattttt cagataacgt tggtaaactc ggtaagcacg attgctaatg
    43081 ttcccctctt cataggcctg ctccaaacca tcactttcaa tactaagaat caagagtttc
    43141 aaagcagccc aatcttcttg atcatcctgg ttttcttggc ttaaaatgag attttcaata
    43201 cgtccatgat aattgtcaat agccgcatag aggggaagtt tatttctggt gtcttccaac
    43261 tctttttcca actctagcgt tacttcattc aaaatggcga tatgcatgag ataatccttg
    43321 ctttcttcct cttcatcaga aagatgaggc aagaccaaga gacctgttaa aaagctgaca
    43381 agcgtcacac ctgcaacaag gaaaagcaag agaggatact cctgttctag attacttggt
    43441 atcaagagaa tcgtagcaat cgacaccgtt cccttaacac ctgaaaaggt caagagaaac
    43501 atgtccttca tatacttatt tagctttttc ttgaggcgtc gggttctata ggcataatag
    43561 ccatagatca taataaaacg aatgacaaag aggacaaagg taagggcgat gagagatagc
    43621 aataaaagta gaggattata gattggattg gtcaagatag gttctgctat catttccaac
    43681 tccatcccta aaatcacaaa gacagaaccg ttgagcataa aggtcactgt atgccagacc
    43741 gtctcggtca ccgtatccac ttgggcttcg aggagcgtga ttttcttgaa gcgacttgcc
    43801 tttaaaattc cagcaactac gacggcaata atccctgaaa catggacttc ttctgccaga
    43861 aagaaggtca ctagaggcaa actcaattct aataaaagtt cactggcaat atccgttgcg
    43921 cgcacactta gcaagaaggt atggaggaag cggttggtca tggctgttaa aaatccaatt
    43981 aaaaaaccgc ctaggattga aaagatgagc gaactgctag cttgccccag agaaaaagct
    44041 ccagttgtcc aagctgtcaa agctacctga aaagccacca aaccagaagc atcattcaag
    44101 agtccttcgc ccttaagaat attggacacg cgcttaggaa agctaaaacg ctccgaaaga
    44161 gaggcaaagg ccaccaagtc cgtaggacca agggctgcac caacagccaa gcaagctgcc
    44221 aagggaaggc tgaaccaaag aagatgggcc aagccaccca aactcagggt cgagataaaa
    44281 atcactggaa atatgagata aacaatgatt cgccagtgtt ttaaaatagc cgtaacatct
    44341 gcttcttcag cctctcggaa aagcaagggt ccgataacca gtgccaaaaa caactccgta
    44401 ttaaggtgaa agtcagtatt gggtaaaaag agaccaatca caattcccaa aagaatctgc
    44461 accaaaggga gaggcaaaaa gggcaggagc ttattggttg tacttgagac aatcaaaacc
    44521 agtaaaaata ggatgaggta aatcagtaat tccacgcacg tcctccttaa tcttttttac
    44581 aacaggattc aaatatctcc ttctgctctt tgattttttg gtcaatcttg gaacagtctt
    44641 tgtgctcaat ttttctctgg caccgttcca tttcaagagc aactaatttt ttcttgattt
    44701 taagcatttt tttgctcata tgcgcttggt ctagcacgcc caccgctcgt tcgtggtggg
    44761 ttgattcaac aaaattctgg cgcatggcat ccagcttttc gtgtaggtat tgtttatcca
    44821 tgtctgtatc tctctaattt ttcaatcatc actaaaaacg gcgggttgtt gacttggttt
    44881 aaagttcggt aaatggcagc tgtgtactct tgttggttca actggatcac aaaatccaag
    44941 acagcatctc tctcgaggtc gcctccttca tgaccatagt aaatcataat agcaattcgt
    45001 ccacctttga caagtaagcc acatagcttt tctaatgcct caatcgttgt ctgcggtcgg
    45061 gtgatgacag acttatcagc tgacggcaaa tagcccaaat taaaaatccc tgccttagct
    45121 tttgtcacaa actggtccag tgtctcatgg ccttgcaaga ttaactgggc atttgtcaag
    45181 ccagcctgat gcaaacgctc ttgggtcttt tccaaggctt gcttctgaat atcaaaggca
    45241 tagacttgct tggctagctt ggctaaaaaa agcgtgtcat gaccatttcc catagtcgca
    45301 tccactacga catcctcttt tgtcacgacc tcagccaaaa aatcatgtgc catctcaagt
    45361 ggtcttttca ttttcaaact cctgttttac agccttgcat ccttgaacac ttccacgacg
    45421 tcgcatctcc atctcaatgc tgttgagagc ttcccattta ttgaggctcc acataagccc
    45481 aagcagcata tccctaggcg catctcctgt aattcgatgg atgacgatat gtttgggaat
    45541 gatttccagt tggtcacaga tgaccctgac atattcgtcc tgactcatca attgtaaacg
    45601 tccctcatgg taatctcgtt gcatacgagt atttgtcata agatggagca aatgcagttt
    45661 aatcccttga atatcgttat tcgtgacaca acggcggaca ttttcaacca tcatctcatg
    45721 ggtttcacca ggcaaaccat tgatcaaatg ggaaacaatc tcaatttttg gatactttct
    45781 caaacgcttg accgtttcca cctacaattc ataagaatgc gcacggttaa tcaggtcaga
    45841 ggttgcttca taagtagttt gcaagcccaa ttcaaccgtc acatgcatgc actccgataa
    45901 ctcagccaaa tattcgatgg tttcgtctgg taaacagtct gggcgcgttc caatattgat
    45961 acctaccaca cctggctcat tgatagcctg ttcataacgc tctcgaacaa cttccacctt
    46021 ttcatgggtg ttggtaaaat tttgaaaata aaccagatac ttctgaacat ccggccactt
    46081 acggtgcata aagtcaattt ccttataaaa ttgctcacgg ataggcgcat ctggggctac
    46141 aatagcatct ccagaacctg aaaccgtaca aaaagtacag cctccatgag ccacagttcc
    46201 atcacgattg ggacagtcaa atcccgcatc aatagggact ttaaaagtct tttctccaaa
    46261 gagttttcga taataatcat tcaaggtatt ataagatttc atgactttca ttataacaaa
    46321 aatcacccac aatctcaaaa gcctgacttt cctataaatt cctctgtttc tcgtttccat
    46381 tagccttttt ttatgataca atatgggtat gattttaatg aaattagcat ctattttatt
    46441 attgatactg accttagtcg tctgcattat cctaaccaaa ctttttagat taaaaaaact
    46501 aggacgaaac tttgcggatt tggcttttcc agtcttggta tttgagtatt acttgattac
    46561 agctaaaacc tttacccata atttcctccc tagactgggg ctagccctct cgatcctagc
    46621 cattattctc gtctttttct tccttttgaa aaaacgcagc ttttactatc ctaaatttat
    46681 caaattcttc tggcgtgcag gattcttatt aacccttatc atgtatatag aaatgattgt
    46741 tgaattgttc ttaatgaaat agtcgaatcc ctaagcattt tctagggatt tttgctttct
    46801 ctacaaaata gtatagacaa taacactata caattttata caaagaaaag agtctgggac
    46861 aatagtctct tatatccaaa aaggcaacgg atttgccgtt gcttttttgc atggttacga
    46921 tagtcttggt aaaatagaat tgcccaataa accatttaga aaggctatcc catgcatatt
    46981 cactataaca caaatcaaac aactttacca ctagaaatca gttccttctt accacaagat
    47041 catctcgttt ttactattga aaaagtggtg aataccttgg aggaacgtca cttctacacc
    47101 tcctatcatg cctttgatcg cccgtcttat caccctaaaa tgcttgtatc tactcttcta
    47161 tttgcctatt cacaagggat tttctctggt cgaaaaattg aaaaatggaa gagttagtga
    47221 ccttagattg tttgtttatt gacagaacta agattgaagc caatgccaac aagtatagtt
    47281 ttgtgtggaa gaaaacgaca gagaaattct ccgccaaact tcaagaacag atacaggtct
    47341 attttcaaga agaaatcact ccccttctga ttaaatatgc catgtttgat aagaaacaaa
    47401 agagagggta taaagagtca gctaaaaact tagcgaattg gcactataat gacaaggagg
    47461 atagctacac acatcctgat ggctggtatt atcgttttca ccataccaaa tatcagaaaa
    47521 cacagacaga ctttcaacaa gaaatcaagg tttactacgc cgacgaacct gaatcagccc
    47581 ctcaaaaggg actgtatatg aacgaacgct atcaaaactt gaaagctaaa gaatgtcagg
    47641 cgcttttatc tccccaaggt agacagattt tcgctcaacg caagattgat gtggaacctg
    47701 tctttgggca gataaaggct tctttgggtt acaagagatg taatctgaga gggaagcgtc
    47761 aagtgagaat tgacatggga ttggtactta tggccaataa cctcctaaaa tatagtaaaa
    47821 tgaaataaga acaggacaaa tcgataagga caatcaaatc gatttctaac aatgttttag
    47881 aagtaaaagt gtactattct agtttcaatc tactatacaa taagagaatg actcaaaatt
    47941 aaaaagctag agttccacaa ttggaaatat ctagcttttt tgtggttgag aactattttg
    48001 tctcaggctc tttatcttct atttaggaca agagtttttc tttggtcttt aatgataaag
    48061 aaggtatcaa aatttctagt cttctttttt acctttagta actactaatc ctgcactcaa
    48121 acctagaaga gttaaacctg ctgctactgc tgcttggctt gccgcactac ctgtacttgg
    48181 taactgggct ttattagttt gactagcttc acttgaatca attggttttg tatctgcttt
    48241 ttctgacact tgtggttttt tagcttcttg agctactggt ttggttccaa ccaagacgat
    48301 gcggtctgtc ggaacttcta ccacttcacg gagtttttct tccttacttc catcaggatt
    48361 aatcgctgta aagatacgtt cttttccaac ttttccttct tgttctacac gagtttcacc
    48421 tagatacagt gttgaatctt ttttctcaac tgtcttgtat gccaaatctt tttcaacaaa
    48481 ttcgattttt ggaagatctt cttgtacagc agcaactgtc ttctcagaaa ctggtttttc
    48541 cttagtcaag tggatacggt attccttgac ttgttttcca ctttctgaaa cgaggcgaac
    48601 aagtactgga aagctatctt ctccactatc taccacagtt gaagctactt gattgttttc
    48661 ttcaactgag acttttggcc gttgaccttt ataggtaatt tgatagtctt gacgattttc
    48721 agcgaaatca gcaagttctt ttccatctac aagaatcttt gattgagtgc tttcttgagg
    48781 caattcactt ggtgcaagga aggtcatctc aatcatcgca acaccgctct tatctgcttt
    48841 acgctccata cgccatctca tagctttggc tttgatagct ttaaatgtta cgttgatttc
    48901 atcaccagct gcaatgtctt tatccgcacg ataaggaaca gcttcccaat tttctggatt
    48961 gttgaatgga tggtctgcgt cgtaggcttg gtagtttgaa tagtaggttg gcacttcaaa
    49021 ctctggaccg acatagcgtt ctaaaacgag tttagatggt gcatccgtac cactatctgc
    49081 aaagaactga acttttcctt gtgcaacagt ccgttctaca atcttaccat tttcacggaa
    49141 aatcacaccc gctgatactt ctggattaga agatggtgtt ggtgaccagt ttgtccaacg
    49201 acgattttct gaatgatctc cgtcattgag atagtcaacg cggtcatgag agtttttgtc
    49261 aatatcattg gttgctgaag caaaggcctg gttactgttt tcatcatagt tagggttatc
    49321 tgaaagagtc tcaccaagtt tgtctgtcac tcgtacagtg acctcagcaa caaggttact
    49381 accaaggaca cggcctcgaa cagtaaattg acctgctttt gtcagatttt ccgctggaac
    49441 ttcttcccat tcaactgtca ggtcttttgt ttcgtagccg tctttacctg tgaagtaaac
    49501 tggaacctta gtcggcaatt caagtgcttg acctacttgt agcaagcgag cttgtttaac
    49561 cgcagcaact ggtttatgag aaagtaagct cttatcctta gtgaagtgca gacggtattc
    49621 tcctaagatg tcgccatttt cagctttcgc gatgacacga actggctcac cttcacgaac
    49681 gcttggaacg acggtagcga gaccattgtt gctaacactt gctgtgactg ccggaacttt
    49741 tccatctaca gactcaaggt agtagtctgt caaatcaggg ttgaagtttg ctaagtcttt
    49801 gccgtcaact tggattcttg tttgtccttg cttggctgcc gcaacttgtt tcgcaaagat
    49861 ttgtacctct gtgatagacg ttccacgctt gttatctgct ttaaccatgc gaatacgaac
    49921 agcataggtt tcaactttat caaagctaaa gtggttcatt tctccagcct tgagttgagc
    49981 aggggctttt agattagtaa ctggtttcca gttggcagaa tcattaaaga catggtcctc
    50041 attaccaaca aaactagggt ttttaggagc tgttgggaca gtcttaccaa cataatactc
    50101 aatcacataa gacttcggta caccaactcc atggtcttca tggaatccga cacttagatt
    50161 atcaacggag cgtttgctca agatacctga atctccaaac agaacaccga ctgaagcttc
    50221 tggattagta cgattccagt ttgtccaacg attggctggt tggttattgt aggaaatgag
    50281 cttgtcatta acatttgaaa ctgggtcgct tggatttgag tctgaagcaa aggcaagtgg
    50341 caattctgaa ccggtccatt ggtcagaaat gtttgcacct tgctcagttt gagcagatac
    50401 gcgaacatga agtttagttg ttaattgcgt accttctaag cgaccattaa ctgtaaagac
    50461 accttcctta gcgtattgct ctggacgaat cgcatcccat gcaaccttag ctgatgaaac
    50521 gtgaccattt gaatcatatg tccgaacact ttctggtaat tgtggtgctt ctgcgattgg
    50581 agttgtcaca ctgacttctt caactgaaac gataccttct acagagactt ttgcacgcgc
    50641 ttcaaggtca attccttcaa ctttacctag tacttcaaat gtttgatagg agtctagttt
    50701 ttctttcgga atagcttgcc aagtgacttt atgagtttta gggaaacctt tgtcatactc
    50761 aactgttact gttgctggaa gacttggttc ctgatgcaaa tctgtcacta catttacagg
    50821 acggatggat tgcgcaatct tcttctcagt attggcttgg atagtgagtt caacttggtc
    50881 tttagctccc tcatattcag cgttcagagt gactgctcct ggcttatgca actcaagcat
    50941 tcctttacga attgcgactt ccccttcacc acttgtagag aaggttactt tatcagctgg
    51001 taatacagct tgcgttccat cttgatagtg agctcgaacc gacaatttga cagtttggtc
    51061 ttctttgaga ctgtcagctt tttccacttg caagctcaag tgagcaattt ttggcgcttc
    51121 ttcaaggaat tgaattgcat aggtttgaag agggccacca tctttaggct gaataaagat
    51181 gctcgcacgc atgccgtttg ctgcgcttgc ttgaagaact gtcacatcag cattttcagc
    51241 acttgctgtg acttctggca attgggcacc ataagataga gtacgatatt gcattggttg
    51301 tcgactagta agacctgtta ctgcttcacc tccaacagta acagttggca ctacaggtgc
    51361 tgcagcattt ccttcttcta ccacaagggt tgcatgaata gtttctccag ctaactgacc
    51421 agtcatttga atacgtgatc cagctactga aagtttggct ttatctactt ccgtaatctc
    51481 ccagctatct acttcgtact cttgtacact tccatcagtc aaaacataag aaacagattt
    51541 gtctacagaa ttcaagtcag tatttggagc aatacgttta actgttggta attctttcgc
    51601 aattgctaga accttgacat gagcctctac ctcacgtcca tttgctgtac ctttaacagt
    51661 cacaactcct gcttgactaa catcgacttg agaccaggtt acaggacgtt ctgcacggct
    51721 accatcactg tatacaaacg gaacagtggt aggcatttca ggtgcctctc caataatggt
    51781 ctgtactttt ggcacttctg tccccaaaac agtcttctct tgtccttctt tcttaccagt
    51841 aaagacagtg acttggttcg atttcaagag atcagagtgg gcagtaaggg tgaatttccc
    51901 tgcttgttca gttgatttga caatggcaac acctttacca ttaaatgctt tacgaatcca
    51961 agaaccatct gcttgcgcct tatagcgttc acggctggct tgttctccgt tatctacacc
    52021 gaccagttga ccttgaccat gcaattggaa gcgaaccaga ttattagcag ttggaaccac
    52081 attcccctgg ctgtcaacaa tttcatagta gatgtaagtc aagtcttttc catctgctgc
    52141 aatcgcatga tcttccttaa taagacgaac tgccgctggc ttaccagcag tcgtaatctt
    52201 atctcgagca atttccttgc cagattcatc acgagcaatt gcttccaagg tacctggttg
    52261 ataggcaact ttccattcaa gataaagttc attagcattt gcaccttctt ggtaagtccg
    52321 cccatcgctg gtttgttttt tattgaaagt cttaagacca agagattttc cattcaagaa
    52381 caattctaca ctagaagcat tcgaataagc acgaactgga atcttacctt ctgagtcagc
    52441 tactttggat gctaattctt tgttttccca gttccagtga ggaagaaggt gtaccatcgg
    52501 tttcttctta acagaaaccc attggctttg gtagagatag aagtcatgtt ttggaatgcc
    52561 ggctgtatct acgataccaa agtaagagct cttaacggga gtttgatttt ggttgtgcca
    52621 tggtgtaggt tcaccaatat agtccgtacc tgtccagata aactgtccag catagccagc
    52681 gttgtcacgg tcaaaagtcc atgaagcggt tgctgttttc ccccaaccca cacgatcatt
    52741 tccataatct gactgttcat aattacgctc aggtccattg ctatgtttca attcacgttc
    52801 agggcgatag taacttcctc gtgtacgggt tgctgatgat gtttctgaac cgtaaatcaa
    52861 ccattttgga tgcttagctc taagggcttt gtaattatct tcagaatagt taaatccaac
    52921 agcatcgagt tcatcagcaa ttttctcatg ccctccgcta ccattaccga aacggaattt
    52981 atctgctccc atggtaacat agcgagtctt atcaacatcc ttgataacct tgaccaaacg
    53041 tttaacagtt gctaaagagt gggcatcacc attagcttca cctatttcat taccaattga
    53101 ccacatgaag atagcagggt tgtttttgcc tctttcgacc atggtacgta ggtcaaaatc
    53161 agaccatttt tcaccttttc gagcttctgg gtgagtggca tctttttcaa agaaacgtcc
    53221 atagtcataa ggtttcttgc caccatacca agtatcaaag gcctcttcct gaacgagtaa
    53281 acctagttct gctgcgattt gcaaggtttg ctcactagca gggttgtggg ttgtacggat
    53341 ggagttaact cccatctcct tcatttgttt gagacggcga tattctgctt tatagttttc
    53401 ttctgctcca agcgccccat ggtcgtggtg caaggatact ccatggaatt taatacgttc
    53461 accattcaaa gagaaacctt catttggagt ccagtgatag taacggtaac caaacaaatc
    53521 cttcttagca tcaaccaatt gaccgtcacg gtaaacacgc gtaatcaatt cgtacaaggc
    53581 aggtttgtca tttaaaacgg tccagagttt tggtctttca acttctaaaa tcgcatctag
    53641 gcttgttgat tcatgtgctt ttaaggtacg actcgctgta cgaactaagc ctgttacagc
    53701 atgaccacct cgttcaacga tttgatattc ggctacaagt tcatggtctt tgtcgtccgt
    53761 attgacgatt ttgctggtca catgagtttc aaccttgcca tgttgttgtt cttcaagttt
    53821 tggtgttaaa atagttgtcc catttttctc aacatgcacc ttatctgtca cttgtaaagt
    53881 cacatcacga tagataccac ttcctgaata ccaacggcta cttggctgtt tgttgactgc
    53941 atggacagca atcacattct cacgaccatc tttgtaaagg tatttggtga tatcgtatga
    54001 gaactggtta taaccatttg gataatgccc cactaactga ccattgacat aaacttgaga
    54061 atccatgtag acgccatcaa aagtaaggcg aacatttttc ttgaggtctt tttcatctag
    54121 tttgaaagtc ttgcgatacc aagcttcccc accgttgagc tgtccacctt cattttgtgc
    54181 aggagattca tgatcgaaat cgttaaagat actccagtca tacggtaaat ctaatttttt
    54241 ccacgtagat acgtctgcat caggtttaat ggcttcctta gaatttgcat tgagtttaaa
    54301 gtaccaattt tgattaaaat ccactttcct gttttcaatc atttgattca cttcttcatt
    54361 tgttacagct ttagcatctt ccttgagcgg tttttcttga cttgaagctt gtgattctat
    54421 ccttggagct ttttcttccg gtttagcaga cactttttcc tcttttggag ttacggcttc
    54481 atcttctttc ttctcagatg caatagcctc agttgaacta ggttcacttt gttctgtcct
    54541 ttcaactaca tttttagttt ccaaagcttt atcagccttt tcttctacta tcattttttc
    54601 ctctttaggt ttctcagcag tatgagtaat aagtgtttca tccgcataaa ctacagattc
    54661 tccagctata tttcctccta atagaactgc acaagtccca atcattactg agcaagctcc
    54721 cacagcaaac ttacgaatgc tataaactct tttccgattc caatggcctt tccccataaa
    54781 accctcctta tattatattt agtgcagtta gctactgcca aagcccaagt ggtatacatg
    54841 gtatgacaac ctagtttcaa caatttacac tctgcgaaaa tccaattcaa acttcgtcag
    54901 tgtcgccttg ccgtagatat gattactgac ttcgtcagtt tcatctacaa cctcaaaacc
    54961 atgttttgag ctgacttcgt cagtcttatc tacaacctca aaactgtgtt ttgagcaacc
    55021 tgtggctagt ttcctagttt gctctttgat tttcattgag tttatatttt ataggagcgc
    55081 attattttgc ttttgctgcg tactcttcgt tacgtttgat catttgtttt ctgtaccaag
    55141 caaagatacc gatatagaat acaaggaaga ctactgcacc aaggattgct ttgatatcac
    55201 cagttgtagt gttaccaatt gtccaaccaa gaagtttttc gattggtcct tcaagagtag
    55261 agtgagtaat caattgagtt tggctcacac cttctgggaa ggcacctaca cctttagcaa
    55321 gttctgttgc aaatggtgca ataagtgtac ctgaaagaag gaagagtggc aacaagagtg
    55381 ttccgaagat aatcatacgg agcaatttac cacgagttac aaccaagaga gctggagtaa
    55441 cacccatagc gatgatacct gcaagtggca agataccatt tccaactttt gaaagaagca
    55501 ctgcttcaat caacatgatt ggtgcaagta cgttggcaca agcccagatt tcagcacgac
    55561 cagcgatgaa tggccagtca agaccgatat tgaatttacg tccttgaaga cgtttagtag
    55621 caacgtttgt aataccttgt gatagtggtt ctacggctgc gatgaaccat gaaccgataa
    55681 gtgagaagag ttccaaagat acaccggcag tcaaaccaag agacaaccat cctttgataa
    55741 caagacgcca tttatctgca tctgcaacac ctgcaattgg atgtggagtt cccataatac
    55801 cgataacgat accaaggatg aaaccgatga agaatttaga tccccagaaa ccgattttct
    55861 tgttcaattt agcagcatca aagtcatatt tatcaaggcc tgggaagaat ttttcaaaaa
    55921 tcttatccaa aaccatgata actgggttca tcatgtagtt catgtgagtt gatgtcattg
    55981 gtgatgaact tggggcgtta agaaggtcat caaatgtagg tttcatcaag tcagagttga
    56041 taattttcaa cacaccgaca aggacgatag ctgctgtagc aataaagagt gaaacccctt
    56101 gactcacacc attgttatca gcataccatt taatcaagag acctgtgata gacaagtgcc
    56161 agatatcaaa gatatcaacg tcaagtgtat ctgttttctt catagctagc atcactatgt
    56221 tgacaatcaa catgatgagc aagaagtata gtgtccaagc agaaccccaa gtgattgttg
    56281 cgagtggtgc ccaaccaacg tcggtaatac tcaattggat accagtgttt tcaacgaatt
    56341 ttgcaagtga tgctgagaaa gcaccattta gcataccgat gatagcaccg atacctgtaa
    56401 gagcgatggc aagtttgata ccaccttcaa gcgctttgga gaatttcact ccaaaaagta
    56461 aagccaatac tgtcaaaatg attaacatga tgacaggtcc acccatttct aaaatgggat
    56521 tgaaaacctt tccgattagg tcaaagattg catccataac agttcctccc ttttttatgt
    56581 tatatgaatg ttaacaaatt agaattagct taatccgtgt tctttaatag ctgcttcaat
    56641 attgtcaaat actggagcgc tcattgctgg gatacggaat aagattggcc cagcttcgat
    56701 aactgggata cctggttcaa aaccaaggtc tgttgcagcg attggtgtaa agatatcgta
    56761 acctttcata aggtcttcgt ttacatcttt caccatgact gcatcacagt gaacatcata
    56821 accacggttt gaaagttctt cttctagagc acttttaatt tggtgacttg agttaacacc
    56881 tgcaccgcag gcagcaagaa ttttaatcat ttggatttcc tccgatttta ttttttaata
    56941 gacaagatta agcggttgct tcagcaatgt aagcataaag tttttctggt tcggaaattt
    57001 ttgataggtc ttcaagatgt ccatttcctg tgaaaaagtc catcaactga gccagaatat
    57061 ttgtttgact tgaacttgaa ttgttaataa taaagaagag tagggatact tctacttcct
    57121 tatcaggagc tatcatattg tgaaaagtta ctggtttttc taatcgaaca accaccactt
    57181 tctcagctag attatgaaca atatctgtat gaggaatcgc tacatttggc aagtcctttc
    57241 ctagaaattc catatctaaa ccagttggaa atgacttttc acgcgtgatc aaggcttcac
    57301 gataagttgg agtgacaatt tctcgttctt ccaataaagt tgcaacctga tcaaagagtt
    57361 gttcttgatt atccgcttct aagcaaaaca caaggttttt gtcaaagaaa taatctaata
    57421 ccataagttt ttcccttctt tccattaact ttatgccata agtataacac tatatgaaac
    57481 cgttgtcaat tgctttctgt tctttttttg tctctttttt tatatttttg ttttgtttat
    57541 agtttgttat ataaaaataa acacacaaac aaatactcca agtatttttt ctgttctaat
    57601 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aaacacagtt
    57661 ttgaggttgt agataagact gacgaagtca gtgatcatat cgtaaccgcc caataacga
//
LOCUS       DAYYYC010000006        56923 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.006, whole genome shotgun sequence.
ACCESSION   DAYYYC010000006 DAYYYC010000000
VERSION     DAYYYC010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56923
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.006"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(99..632)
                     /gene="queF"
                     /locus_tag="ACHBV5_000341"
     CDS             complement(99..632)
                     /gene="queF"
                     /locus_tag="ACHBV5_000341"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HFM9966209.1"
                     /translation="MKRQSALVVFSGGQDSKTCLFWTMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(939..1253)
                     /gene="trxA"
                     /locus_tag="ACHBV5_000342"
     CDS             complement(939..1253)
                     /gene="trxA"
                     /locus_tag="ACHBV5_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFM9966210.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(1270..1491)
                     /locus_tag="ACHBV5_000343"
     CDS             complement(1270..1491)
                     /locus_tag="ACHBV5_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HFM9966211.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(1590..1970)
                     /locus_tag="ACHBV5_000344"
     CDS             complement(1590..1970)
                     /locus_tag="ACHBV5_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFM9966212.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(2115..3068)
                     /locus_tag="ACHBV5_000345"
     CDS             complement(2115..3068)
                     /locus_tag="ACHBV5_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFM9966213.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(3136..4344)
                     /gene="sstT"
                     /locus_tag="ACHBV5_000346"
                     /pseudo
     CDS             complement(3136..4344)
                     /gene="sstT"
                     /locus_tag="ACHBV5_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            4483..5043
                     /locus_tag="ACHBV5_000347"
     CDS             4483..5043
                     /locus_tag="ACHBV5_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HFM9966214.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            5100..6008
                     /locus_tag="ACHBV5_000348"
     CDS             5100..6008
                     /locus_tag="ACHBV5_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFM9966215.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            6023..6550
                     /locus_tag="ACHBV5_000349"
     CDS             6023..6550
                     /locus_tag="ACHBV5_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFM9966216.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            6553..7659
                     /gene="yqeH"
                     /locus_tag="ACHBV5_000350"
     CDS             6553..7659
                     /gene="yqeH"
                     /locus_tag="ACHBV5_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFM9966217.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            7873..8184
                     /gene="yhbY"
                     /locus_tag="ACHBV5_000351"
     CDS             7873..8184
                     /gene="yhbY"
                     /locus_tag="ACHBV5_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFM9966218.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            8236..8865
                     /locus_tag="ACHBV5_000352"
     CDS             8236..8865
                     /locus_tag="ACHBV5_000352"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFM9966219.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVEYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            8865..9458
                     /gene="yqeK"
                     /locus_tag="ACHBV5_000353"
     CDS             8865..9458
                     /gene="yqeK"
                     /locus_tag="ACHBV5_000353"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFM9966220.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVGKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            9459..9959
                     /locus_tag="ACHBV5_000354"
     CDS             9459..9959
                     /locus_tag="ACHBV5_000354"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFM9966221.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEEHFADVL
                     DYKHIF"
     gene            9972..10325
                     /gene="rsfS"
                     /locus_tag="ACHBV5_000355"
     CDS             9972..10325
                     /gene="rsfS"
                     /locus_tag="ACHBV5_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFM9966222.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            10434..11174
                     /locus_tag="ACHBV5_000356"
     CDS             10434..11174
                     /locus_tag="ACHBV5_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM9966223.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            11184..12281
                     /locus_tag="ACHBV5_000357"
     CDS             11184..12281
                     /locus_tag="ACHBV5_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFM9966224.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVNILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTARSVEELVELVTTKRY
                     TKARVRRLLTYILMQARENVLPEVIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNPSIADQNFGRVPIRIETN"
     gene            12519..12773
                     /locus_tag="ACHBV5_000358"
     CDS             12519..12773
                     /locus_tag="ACHBV5_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFM9966225.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            12777..13031
                     /locus_tag="ACHBV5_000359"
     CDS             12777..13031
                     /locus_tag="ACHBV5_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFM9966226.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            13222..14835
                     /locus_tag="ACHBV5_000360"
     CDS             13222..14835
                     /locus_tag="ACHBV5_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFM9966227.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            14965..15591
                     /gene="gmk"
                     /locus_tag="ACHBV5_000361"
     CDS             14965..15591
                     /gene="gmk"
                     /locus_tag="ACHBV5_000361"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFM9966228.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            15616..15930
                     /gene="rpoZ"
                     /locus_tag="ACHBV5_000362"
     CDS             15616..15930
                     /gene="rpoZ"
                     /locus_tag="ACHBV5_000362"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFM9966229.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            15996..18392
                     /locus_tag="ACHBV5_000363"
     CDS             15996..18392
                     /locus_tag="ACHBV5_000363"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFM9966230.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQVRILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTRNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            18405..19340
                     /gene="fmt"
                     /locus_tag="ACHBV5_000364"
     CDS             18405..19340
                     /gene="fmt"
                     /locus_tag="ACHBV5_000364"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFM9966231.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPNRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSICKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            19333..20646
                     /gene="rsmB"
                     /locus_tag="ACHBV5_000365"
     CDS             19333..20646
                     /gene="rsmB"
                     /locus_tag="ACHBV5_000365"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFM9966232.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVALKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFANGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            20661..21401
                     /locus_tag="ACHBV5_000366"
     CDS             20661..21401
                     /locus_tag="ACHBV5_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFM9966233.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            21398..23377
                     /gene="stkP"
                     /locus_tag="ACHBV5_000367"
     CDS             21398..23377
                     /gene="stkP"
                     /locus_tag="ACHBV5_000367"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HFM9966234.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            23492..24250
                     /locus_tag="ACHBV5_000368"
     CDS             23492..24250
                     /locus_tag="ACHBV5_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFM9966235.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            24252..24701
                     /locus_tag="ACHBV5_000369"
     CDS             24252..24701
                     /locus_tag="ACHBV5_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFM9966236.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            24763..25389
                     /locus_tag="ACHBV5_000370"
                     /pseudo
     CDS             24763..25389
                     /locus_tag="ACHBV5_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            25457..25705
                     /locus_tag="ACHBV5_000371"
     CDS             25457..25705
                     /locus_tag="ACHBV5_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966237.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            25836..27008
                     /locus_tag="ACHBV5_000372"
     CDS             25836..27008
                     /locus_tag="ACHBV5_000372"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFM9966238.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTVLSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            27008..28282
                     /locus_tag="ACHBV5_000373"
     CDS             27008..28282
                     /locus_tag="ACHBV5_000373"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFM9966239.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQDDPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(28318..29283)
                     /locus_tag="ACHBV5_000374"
     CDS             complement(28318..29283)
                     /locus_tag="ACHBV5_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM9966240.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVTTTGYFLPVTLLPGKSI"
     gene            complement(29264..30718)
                     /locus_tag="ACHBV5_000375"
     CDS             complement(29264..30718)
                     /locus_tag="ACHBV5_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFM9966241.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            31094..32977
                     /locus_tag="ACHBV5_000376"
     CDS             31094..32977
                     /locus_tag="ACHBV5_000376"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HFM9966242.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFIIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFETKV
                     AQGDKVKVGDVLGTFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            33126..34013
                     /gene="scrK"
                     /locus_tag="ACHBV5_000377"
     CDS             33126..34013
                     /gene="scrK"
                     /locus_tag="ACHBV5_000377"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFM9966243.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(34056..34673)
                     /locus_tag="ACHBV5_000378"
     CDS             complement(34056..34673)
                     /locus_tag="ACHBV5_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HFM9966244.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(35088..35276)
                     /locus_tag="ACHBV5_000379"
                     /pseudo
     CDS             complement(35088..35276)
                     /locus_tag="ACHBV5_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(35669..35860)
                     /locus_tag="ACHBV5_000380"
     CDS             complement(35669..35860)
                     /locus_tag="ACHBV5_000380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966245.1"
                     /translation="MKSKEQTRKLAVGCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            35982..36875
                     /locus_tag="ACHBV5_000381"
     CDS             35982..36875
                     /locus_tag="ACHBV5_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966246.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            36872..38071
                     /locus_tag="ACHBV5_000382"
     CDS             36872..38071
                     /locus_tag="ACHBV5_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9966247.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLEQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(38424..39191)
                     /locus_tag="ACHBV5_000383"
     CDS             complement(38424..39191)
                     /locus_tag="ACHBV5_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966248.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(39208..39903)
                     /locus_tag="ACHBV5_000384"
     CDS             complement(39208..39903)
                     /locus_tag="ACHBV5_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966249.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(39908..40273)
                     /locus_tag="ACHBV5_000385"
     CDS             complement(39908..40273)
                     /locus_tag="ACHBV5_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFM9966250.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            40413..40886
                     /gene="nrdR"
                     /locus_tag="ACHBV5_000386"
     CDS             40413..40886
                     /gene="nrdR"
                     /locus_tag="ACHBV5_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFM9966251.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            40887..42056
                     /locus_tag="ACHBV5_000387"
     CDS             40887..42056
                     /locus_tag="ACHBV5_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFM9966252.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFNPKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            42057..42953
                     /gene="dnaI"
                     /locus_tag="ACHBV5_000388"
     CDS             42057..42953
                     /gene="dnaI"
                     /locus_tag="ACHBV5_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFM9966253.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            42950..43663
                     /locus_tag="ACHBV5_000389"
     CDS             42950..43663
                     /locus_tag="ACHBV5_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HFM9966254.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAKMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            43677..44987
                     /gene="der"
                     /locus_tag="ACHBV5_000390"
     CDS             43677..44987
                     /gene="der"
                     /locus_tag="ACHBV5_000390"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFM9966255.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            45078..45413
                     /locus_tag="ACHBV5_000391"
     CDS             45078..45413
                     /locus_tag="ACHBV5_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966256.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            45553..45888
                     /locus_tag="ACHBV5_000392"
     CDS             45553..45888
                     /locus_tag="ACHBV5_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966257.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            46073..46864
                     /locus_tag="ACHBV5_000393"
     CDS             46073..46864
                     /locus_tag="ACHBV5_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966258.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILHVVPYMVLKKYEDNV"
     gene            46857..47498
                     /locus_tag="ACHBV5_000394"
     CDS             46857..47498
                     /locus_tag="ACHBV5_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966259.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            47502..48152
                     /locus_tag="ACHBV5_000395"
     CDS             47502..48152
                     /locus_tag="ACHBV5_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFM9966260.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            48163..48450
                     /locus_tag="ACHBV5_000396"
     CDS             48163..48450
                     /locus_tag="ACHBV5_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966261.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     MQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            48596..51109
                     /gene="secA"
                     /locus_tag="ACHBV5_000397"
     CDS             48596..51109
                     /gene="secA"
                     /locus_tag="ACHBV5_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFM9966262.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMATLTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            51190..52221
                     /locus_tag="ACHBV5_000398"
     CDS             51190..52221
                     /locus_tag="ACHBV5_000398"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFM9966263.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            52223..53254
                     /locus_tag="ACHBV5_000399"
     CDS             52223..53254
                     /locus_tag="ACHBV5_000399"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFM9966264.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            53299..53661
                     /gene="acpS"
                     /locus_tag="ACHBV5_000400"
     CDS             53299..53661
                     /gene="acpS"
                     /locus_tag="ACHBV5_000400"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFM9966265.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            53651..54754
                     /gene="alr"
                     /locus_tag="ACHBV5_000401"
     CDS             53651..54754
                     /gene="alr"
                     /locus_tag="ACHBV5_000401"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFM9966266.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLALPYDLIPALTLESALVHIKTVPAGACMGYGATYQTDSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            54773..56788
                     /gene="recG"
                     /locus_tag="ACHBV5_000402"
     CDS             54773..56788
                     /gene="recG"
                     /locus_tag="ACHBV5_000402"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFM9966267.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHYMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIETWQEDPEWRMIALHLEKKEHLD"
BASE COUNT        16827 a        10960 c        12989 g        16147 t
ORIGIN      
        1 agctgacttc gtcagtttta tctacaacct caaacactgc tttgagtaac ctgcggctaa
       61 cttcctagtt tgctctttga ttttcattga gtatgacttt agcggttgtc aattttctct
      121 ggataaaggt cgtgttggaa gaggcgttgt tctgccaagc cctcatactt agttccttgc
      181 ttaccgtagt tatagtaggg gtcgattgaa atgccaccgc gcggagtgaa ttttccccag
      241 acttctaaat agcgagggtc tagcaagttg accaagtctt tcccgatggt gttgatacag
      301 ttttcgtgga aatctccgtg gtttcggtag ctaaatagat atagtttgag ggattttgac
      361 tcgacacaga gcttgtcagg aatgtaggaa atatgaatcg tcgcaaagtc tggctgagca
      421 gtgatttgtc ccagcagaga catatcgagg atatggtgac gaatgccctg ttccttagcg
      481 atttctctag taatttgaat ttcgaggtga tgacgttggc cgtaggcaaa ggtgacagct
      541 tcgactgttt catagtgttg catggtccag aaaaggcagg tttttgaatc ttgaccacca
      601 ctaaagacga ccaaggctga ttgacgtttc atagtactcc ttccaaaatg ggaaatgttc
      661 agagcacgta aaaagctccc attagggagc taaaaaatac caaatcgagg ttttttttag
      721 cgatggcata tcccaaatat cgtaatattc tatttatata gtaaaatgaa ataagaacag
      781 gacaaatcga tcaggacagt caaatcgatt tctaacaatg ttttagaagt agagatgtac
      841 tattctagtt tcaatctact atagtctagc atatcttttg aaaaatggca aagggcaaga
      901 aaaaagagac caaagaaagt acttggtctc tcgtttgatt agctcaattc agcaatgatg
      961 gccttgattt gttctgctgt gtgaacacct gcaacttgtt tgacaacttg gccgtctttt
     1021 ttgaagagaa gagttggaat agacatgatt ccaaaagcac gagctgtgtt tggattttca
     1081 tcaacgtcca ttttaacgat tttcaagaca tcttctgaaa gttcttcaga caatttgtcc
     1141 aagattggac cttgcatacg acatggacca caccaagttg cccagaagtc tactaagacc
     1201 aaaccgtctt ttgtttcttg ttcgaatgtt gcatctgtaa ttgcttttgc cattgtattt
     1261 ctcctttttt tagttatatt ggcttaaatc ttgtttcatg agatagaaga agatatctcc
     1321 ataagtccca tggtagtcca aattatgacc cttgtaagtt aatttttgga cagggtagta
     1381 gtctgcgacg ccgataaggc aagcttgttg cgaacgttca aagtcttcat aagactcgaa
     1441 agtcacagtt ctttcgttct tgctggcatc tatataggta atttcaatca tgtttaaaac
     1501 tcctttgttt aatgctaact ttattttact ccttataaaa gagaatgtca agaaaaatga
     1561 ttgcgcacgc aacttttttt aaaatcatct taaatcaaga aatccaaacc tgcttccaag
     1621 ctttcttcga cagtcttttg tagcgaggcc agtgtctttt gcccatcatt tgtcaggcag
     1681 ataaaactag agcgtctatc ttgatggcaa cacatgcgac tgagtagacc gcaattttta
     1741 gcttccaagc gagccaccat cctagaaact gcgctcgggc tcagatgaag cttatctggc
     1801 aggtcaatct ggcgtagaga tttttcttca gccaagtcca gatagtagag caggtagaac
     1861 tctttcaagg tcagactttg ctcgctctgt tgggcaatgg tctcttccaa gagactttca
     1921 atttctttct gacgccgatt gaagtcaaac catttttcca aataggtcat agtgtctcct
     1981 ttctttttag agtcataatt atagaagaaa gtccattaac gggcagtctt tgcgtcataa
     2041 gatgattgcg catgcaataa ttatactact tttcaagaat gctggcaagc tctgtttttt
     2101 agtggttttc ttttttactg tctatatttt tggtaaaaat caacttttac ttggatgaag
     2161 gttttggctt cacgtaggag ttgaagaaga gtggcgcggg tttcaaactc ttctcttgtc
     2221 ttgggcagac tgcggttccg gaagacttcc agataacgtt caatttcatc tagcaaatca
     2281 gaagcaggat tggtctggct cagttgacct gcaatttttg aaaagagttg cgctaagatc
     2341 aggctttcac tggcggcaag gtgacaagtg ttaatctgtt gggccatgtt tctcaggata
     2401 cgactttgtc gttgtctcat ctcaaagtag tggatatggt agtcggtctg gtgaaagagg
     2461 tggtcagagt gatccaaata gaccagtctg agggcttctt tcaaaagcgt gtctaattct
     2521 gctaccagct gtgctcggtt gcgtccgtct cctctggata aatagtattt gaagcgctgg
     2581 aggatatctt ttaacttttc ttccaccagc gtgtggtagt gctggatttc ctcttctcgt
     2641 gaaggcatat agagattaac aagcaaggca aatcctgtac caatagcaaa gagaaggaat
     2701 tcgttgacta ggaggtctgg agaggttgac tcttgaacca agagatggct aaccaaaacc
     2761 gtgcttggtg tgatgccaat ttcccagccc atcttgtagg ctaaaggaac gtagaaggcc
     2821 agatagaggc cgagactcca gatatgaaat ccgctcaagt gaaaagctag aacgccgata
     2881 gccagagcta gaagcataga aaaaagacga ttgcgagcca gttttaaagt acttctacgc
     2941 gtatcagata ggctcaagag agcgataatt ccagccgaaa ctgctgacga aagattgaga
     3001 aaataagcaa gcaggcaggc aagacaggta gctaagatga gcttggtcgt acgttggcta
     3061 atagacataa gaatttccta ataagttaga ataaaagcgt aaaagacaag acatgagcag
     3121 gcttgccttg atgagttatt ttttacgggt tgctgcgtat tcggcaacgg cggtaaagag
     3181 gacatctgta gaagagttaa gggctgtttc acatgagtct tggatgacac caatcacaaa
     3241 accaacccca acaatttgta tggcaatatc gttagaaata ccgaaaaggc tacaagcaac
     3301 tgggataaga aggagggaac ctccggcaat acctgaagca tcacaggctg agatagctgc
     3361 taccacactg aggacaaagg ctgtggcaaa gtcaacagga attccaagag tgttaactgt
     3421 aacaagggtc aaaacgttaa tggtaatcgc tactccagcc atattgatag tagaaccgag
     3481 tgggatagaa acagaatagg tatctgggtt gagtccaagg tcatggcaga gtttcatgtt
     3541 gacaggaatg ttagtcgcag aactacgagt gaaaaaggct gtcacaccgc tgacacggag
     3601 gcagttccaa actagagggt aaggattgcg tctcataaag aagaaggcaa tcaaagggtt
     3661 gaccacaggg gcaacaaaaa gcatagtcgt tactaataga accaataaaa taccgtagtt
     3721 ggcaaggctt ccgactccct tgtcagaaat ggttttaaaa acaagaccaa ggattccaaa
     3781 tggagccaga ttgatgatcc attcgacaat tttagaagtc acgtcagcga tagtttttag
     3841 caattcttta ctatttttac tggcttctct catagcgatt ccaaaaatga ctgcccaaga
     3901 taagattcta atatagttag cagtaagcag ggcgttgact gggttgtcaa ccagtttgag
     3961 caagaggttg ctgaggacct gcccaatccc atctggtggt gcaatttcag tattggcact
     4021 atttagggta atttcaatag ggacgatgaa acttgctagt acagctacaa gagcagcggc
     4081 gaaagtccct atcataggat atacaagaaa acaacagttt tcatattgct atcttgtccc
     4141 ttttgatgtt ggaaagggca ttggcaacga gggcaaagac taggatagga gcaacagctt
     4201 ttagacctcc aacgaataaa tccccgagta gcccaatccc tgagagatta ggaagggtca
     4261 gtcctaggat tccccacaaa gcataccaat caagatacgc ttgacaaggc ttgccttatt
     4321 ccaagcatga atgattcttt tcataataat ctcctttttg tgtagtgatt atgattatag
     4381 tataaatgat agacaaaatc aagaattttc tgtctatttt ttgaatattt atggagaatg
     4441 agactgatga aaatatggta taatgaaata aaggagtttt atatgcaaaa atttattcag
     4501 gcttatattg aaaagctaga tgtgacaacc attatcgaga atattctaac caaggtcatt
     4561 tctcttttac tgcttttgat tgtattttat attgctaaaa aaatgcttca taccatggtg
     4621 cagagaattg tcaaaccttc tctaaaaatg tctcgtcatg atgtcggacg ccaaaaaacc
     4681 atctcacgtt tactagaaaa tgtgtttaat tatacgctat atttcttttt actctactgc
     4741 attttgtcga ttttaggttt gccagtttct agtttgctgg ctggagctgg tattgctggg
     4801 gtagcgattg gtatgggagc ccaaggcttt ctgtctgatg tcatcaatgg ctttttcatc
     4861 ctctttgaac gtcaactgga tgtgggagat gaggtcgttc tgacaaatgg accgattact
     4921 gtatcgggta aggttgtcag tgtgggaatt cgtacgacac agcttcgtag cgaggagcaa
     4981 gcccttcact ttgtccctaa ccgaaatatc acagttgtta gcaatttctc acgcacagac
     5041 tagacctgtt attttaagta atttgtggta caatagaggg agtttaataa ggagaaaaga
     5101 tggttttaga aaagcagttg ggcaatggtt gtacctggat agacctagac ctaggaaagt
     5161 tgaataaact agaagacctt tctgaaattt acggtttgga caaggaaacc attgaatacg
     5221 cactggatag aaacgagcgc gcccacatgg attaccaccg tgaaagtggg acggttacct
     5281 ttatctataa tgtcctagac gtaaaaaagg acaaggccta ctatgagact tttcccatga
     5341 cctttattgt cgagcatcgt cgcctgatta ccattagtaa taccaagaac gcctatgtca
     5401 ttgaacagat gactcgttat ctggagagcc atgacacgct ttcgatttat aagtttctct
     5461 ttgccagtct ggaaattatc agcaatgcct actatcctgt cattgagcag atggacaaga
     5521 gtagggatga ggtcaatgac ctcttgcgcc agcgaactac caagaaaaac ctctttgccc
     5581 tgtctgattt ggagactggt atggtttatc tgacggcagc tgccaaacaa aatcggattt
     5641 tgttagagca tattcaaggt catgccttgt atcgtagttt tgatgagatt gagagagaac
     5701 agtttgatga tgccatgatt gaggctcatc agctggtatc catgacagac ctaatctctc
     5761 agattttaca gcagctttca gcctcttaca acaatattct aaacaataat ctgaatgaca
     5821 atttgacaac cttgactatc atttcagtct tgctagctgt tttggcagtc gtgacaggct
     5881 ttttcggaat gaatgttccc ttacctttaa cagatgagcc ccatgcttgg ctctatatca
     5941 gtttggctag tgcaggtttg tggattgttt tatccttgtt actaaggaaa attgcgaaaa
     6001 aaagttaaga aaaggagcca gaatggcgat tgaaaattat ataccagatt ttgctgtgga
     6061 agcagtctat gatctgacag tcccaagcct gcaggcgcag ggaatcaagg ctgttttggt
     6121 cgatttggat aataccctca ttgcttggaa caaccctgat ggaacgccag agatgaagca
     6181 atggctacat gaccttcggg acgcgggtat tggcattatc gtagtgtcaa ataacaccaa
     6241 aaaacgcgtt caacgagcag ttgagaaatt tgggattgat tacgtttact gggccttgaa
     6301 gcccttcaca tttggtattg accgtgctat gaaggaattc cactatgaca aaaaggaagt
     6361 ggtcatggtt ggcgaccagc tcatgacaga tatacgagca gcccaccgtg cagggattcg
     6421 gtcaatttta gtcaaaccct tggtccaaca tgactcaatc aaaacgcaga ttaaccgaac
     6481 tcgtgagcgt cgtgttatga gaaaaatcac tgaaaagtac ggaccgatta catataaaaa
     6541 aggaatttaa ctatggaaga aattctctgt attggttgtg gagcaaccat tcagacgaca
     6601 gataaagctg gtcttggttt taccccccag tcggcacttg aaaaaggttt ggagactggc
     6661 gaagtctatt gccaacgctg tttccgtctc cgccactaca atgaaatcac agatgtccag
     6721 ttgacgaacg atgatttcct caagctcttg cacgaggtgg gagacagtga tgccttagtg
     6781 gtcaatgtca ttgatatctt tgattttaat ggatctgtca tcccaggttt accacgtttc
     6841 gtctcgggca atgatgtcct cttggtagga aataaaaaag atatccttcc taagtcagtt
     6901 aagtctggta agattagcca gtggctcatg aaacgtgccc atgaagaagg tcttcgtcca
     6961 gtcgatgtgg tcctaacttc agcacaaaat aaacatgcca ttaaggaagt cattgacaag
     7021 attgaacact accgtaaggg ccgcgatgtc tatgtggtcg gtgtgaccaa cgttggaaaa
     7081 tcaactctaa tcaatgctat tatccaagaa atcacgggtg atcagaatgt catcactact
     7141 tcacgcttcc caggtacaac cttggacaaa atagagattc cgcttgacga cggatcttat
     7201 atttacgata cgccgggaat tatccaccgc caccagatgg ctcactactt gacggccaaa
     7261 aacctcaagt atgtcagtcc taaaaaggaa atcaagccta agacctatca gcttaatcct
     7321 gagcaaaccc tatttttagg tggtttggga cgctttgact ttatagcagg agaaaagcaa
     7381 ggatttactg ctttctttga taatgaactc aaactccatc gtagcaagct tgaaggagct
     7441 agtgctttct acgataagca cctgggaact cttctgacac caccaaatag caaggaaaaa
     7501 gaagatttcc caaggctagt ccagcatgtc tttaccatta aagataagac agacctagtc
     7561 atctcaggcc taggctggat tcgtgtaaca ggcatagcaa aagtcgccgt ctgggcacca
     7621 gaaggcgtcg ccgtcgtcac acgaaaagca attatttaaa acaaaatcgc tgagcgaaca
     7681 aagtgagctc atatagcgat agttattgcc gtggtgtgat tgccaatctg tagattggca
     7741 aggggcacaa ttgagaccaa ggctcaattg tgaggtcagg aaatccattt ttcaaagatg
     7801 aaatctttgg aaaattagtt ccgaccgtcc ctcaccacct aaaataacta tccaaaaaca
     7861 aggaagaaaa ttatgtcatt aacatcaaaa caacgtgcct tcctcaacag ccaggcacac
     7921 accctcaaac ctatcatcca aatcgggaaa aatggactca acgaccaaat caaaaccagc
     7981 gtccgtcaag ctcttgatgc gcgtgaatta atcaaggtta ctctcttaca aaacacagat
     8041 gaaaacatcc acgaagtagc tgaaattttg gaagaagaaa tcggtgtgga tacagtccaa
     8101 aaaataggac gcatcttgat tttgtttaaa caatctagca agaaagaaaa tcgcaagatt
     8161 tctaagaaag tcaaagaaat ctaagaccga aactccaaat aactgttttt atagagaaat
     8221 aaaggggact agcctatgac aatcgaacta ttgactccct ttaccaaggt agagttggag
     8281 ccagaaatca aggagaaaaa acgcaaacaa gttgggattt taggggggaa ttttaaccct
     8341 gttcacaatg cccatctcat tgttgcggat caagtacggc aacagttggg actggatcaa
     8401 gttcttctca tgcctgaata ccaacctcct cacgttgata aaaaggaaac catccctgaa
     8461 caccatcgtc tcaagatgct tgagttggca attgagggaa ttgacggcct agtcattgaa
     8521 accattgagt tggagcgcaa gggtatttcc tacacctacg acaccatgaa gattttgaca
     8581 gagaagaatc cagatacgga ttattacttt atcatcggtg ccgacatggt tgagtatctg
     8641 cctaagtggt accgaattga tgaactggtt gacatggttc agtttgtggg ggttcagcgt
     8701 ccacgctaca aggtagggac ttcctatcca gttatctggg tggacgtacc gctcatggat
     8761 atctcgtcca gcatggtgcg ggacttcctt gcccaaggtc ggaaacccaa ctttctccta
     8821 cctcagccag tgctagacta catcgagaag gaggggctct actgatgtcc tatcaagact
     8881 atatcaactg ctcccgtgag gccttgttgg aaaaaatggc agagcttcta cctgagaaac
     8941 gtctaaccca ttgtctaggt gtggagcgtg ccgctatgga attagctcag cgctttggtg
     9001 tagatgttgg gaaagcaagt ctagcaggtc ttcttcatga ctatgctaaa aagttgtcaa
     9061 atcaggaatt tctagccttg attgaccgtt accagctaga ccctgacctc aaaaactggg
     9121 gcaataatgt ctggcatggt atggtcggaa tttacaaaat tcaggaagat ttggatttgc
     9181 atgattctga aattctgcga gccattgaaa ttcatacagt cggagctggt caaatgacag
     9241 acctagataa ggtcatctac gtcgcagact atatcgagca caatcgagcc tttcctggag
     9301 tagatgtggc gcgtgagatt gcaagtctat cgctcaataa ggcggtggcc tacgaaacag
     9361 ctcgtaccgt ggagtatcta gctcatcagg gattccccat ctatccccaa acccttgaaa
     9421 cctataacgc ctttgtgcac tatttgaaag aggactaaat gaagacggct tttataatca
     9481 ttgatgttca gaatgtttta gtagaaactg ggttccagac aaaaagtcta ttggaaaaaa
     9541 tttcttattt acaaaaccag gctagaagca agaatattga aattatctat gttcaacata
     9601 ttgagaattc tgaagctcaa acatcagaag attggcagtt atctgcgctt ttaaatcgaa
     9661 aacctgctga aaaggtcttt cagaagaagt ataacagtat tttcaaagaa actggcttaa
     9721 aagaatactt ggataaacag gggattgaaa aattagtttt atgtggtatg cagacagaat
     9781 attgtgtgga tacctctgtc aaggttgcct ttgaatatgg ctatcagctt attgttccag
     9841 aaggtgctgt cacaaccttt gatggggatg acattccagc agaaacgatt aatgaatttt
     9901 atgaggacat ttgggaggag cactttgcag atgtcctaga ttacaaacat attttctaaa
     9961 aagaggatta aatgaacgaa aaagaattac tagaactagt cgtgaaagcg gctgatgaga
    10021 aacgtgcgga ggatatcctc gcacttgatg tacaagattt gactagtgtg acggactact
    10081 ttgtcatcac tagctcaatg aatagccgtc agttggacgc tatcgcagct aatatccgtg
    10141 aaaaagtagc tcaagcgggc tttaaaggta gccatgtcga aggcgatgca gctggaggct
    10201 gggtcttact ggacctcggt gctgttgtcg tgcatatctt ttcagaagaa atgcgtgccc
    10261 attataatct agagaagcta tggcatgagg cgaattcagt agatatttca gaagctcttg
    10321 cttagaagat gaactcagtt gtagtcaact gggtttcttt gcttatttta gaaaaattga
    10381 tagaaaggta aagggctagt ggtgtttacc atggagctct tagtatcatg attatggcga
    10441 cttatgaaac ctttgcggcg gtctatgatg cggtcatgga cgatagttta tacgacaaat
    10501 ggacgaattt ttctctgcgt catttgccta agaccaagga gaaaaagaaa ctcttggaac
    10561 tggcttgtgg gacaggaatt caatcagtgc gcttctctca ggctggtttt gatgtgactg
    10621 gacttgactt gagtgcggat atgttgaaga ttgcggagaa gagagcaact tcagccaagc
    10681 aaaagattgc ttttatagaa ggtaacatgc tgaatttgtc caaggcaggg aaatacgatt
    10741 ttgtcacgtg ttattcggac tctatctgct atatgcagga tgaggtggaa gtaggggacg
    10801 tctttaagga cgtgtacaat gcgctgaatg aagagggagt tttcatcttt gacgtgcact
    10861 cgacctacca gacagatgaa gtattccctg gctattccta ccatgaaaat gcggaagatt
    10921 ttgccatgct ttgggataca tatgaggacg aagctcctca ctccatcgtg catgagctga
    10981 ctttctttat caaggaggct gacggttcct ttagtcgcca cgatgaagta catgaggaga
    11041 ggacctatga gatcttgacc tatgatatct tactggaaca ggctggattc aagtccttca
    11101 aactctatgc agactttgag gataaggaac caacagaaac tagcacccgt tggttttttg
    11161 tggcgcagaa gtaggagatt agcatgacca tcacaggtat tatcgcggag ttcaatcctt
    11221 ttcataatgg ccataaatac ctgctggatc aggcagaggg actgaaaatt gttgccatgt
    11281 cagggaattt catgcagcgt ggagagcctg ctattgtgga taagtggaca agggcccaga
    11341 tggcgctgga aaatggcgca gacttggtag tggaattgcc ctttttagtc agtgttcagg
    11401 cagctgattt ctttggtcaa ggagctgtga atatcttgga tcgcttgggc attgatagtc
    11461 tagtttttgg gacagaggaa gttcgagatt atcagaaaat cgctgactta tacacagaga
    11521 aaggtgctga gatggagaaa tttgtggaaa atctgcctga ttccctttcc tatccccaga
    11581 aaacccaagc tatgtggaag gaatttgctg gtcttgattt ttcaggtaat acccccaatc
    11641 atgttcttgc tctggcctat gccaaggcgg ttgcaggacg aaatatcaag ctgcatccga
    11701 ttcagcgtca gggggcaggt taccattctg tgaataaaga tgtggacttt gcctcggcga
    11761 cagccctccg tcaacatcag aaggaccaag atttcttaga acgctttatg ccttctgttg
    11821 ccctatttga gcaggccagt aaggtgatct gggaagacta ttttcccttg ctccgctatc
    11881 aaatcttgtc aaatcccgac ctaaccacca tctatcaggt caatcaagaa atggctgtgc
    11941 gcattaaaga agctattaaa acagcccggt ctgtggaaga attggtcgag ttagtgacta
    12001 ccaaacgtta caccaaggcg cgtgtcagac gcctattgac ctatattttg atgcaggcta
    12061 gagaaaatgt cttgccagaa gtcattcatg tccttggatt tactgaaaaa ggtaggcaac
    12121 atctcaagtc tttgaaaggt caggtcagtc tagtcagccg aattggcaaa gaaccttggg
    12181 atgctatgac ccaaaaagca gaccagattt accaactagg aaatccaagt atagcagacc
    12241 agaattttgg aagagtgccg attagaatag aaacaaacta agtctaccga aaggtaggct
    12301 ttttgagatt ttttacgaat aatactcttc gaaaatcaaa ttcaaatcgc gtcaacgtcg
    12361 ccttgccgta ctcaagtaca gcctgcggct agtttcctag tttgctcttt gattttcatt
    12421 gagtataaat agatagaaaa gaaaatcttg tacaagttcc tgacaatttc tttcttttcg
    12481 tgtataatag tggaaaagag ctaaaacgag gtatggttat ggaagcagtc ctttactcaa
    12541 cattccgaaa tcatttaaag gactacatga agaaggtaaa tgatgaattt gagcctttga
    12601 cggtggtcaa taaaaatcca gatgaggaca ttgtagtcct ttcaaagagt gagtgggata
    12661 gtatccaaga aaccctgaga attgctcaaa ataaggaact ttctgataag gttttgcgag
    12721 gaatggctca agttcgtgct ggaagtactc aggtccatgt tattgaggag taagaaatgc
    12781 tgctcaagtt tacagaagat gcctgggcag attattgcta ctggcaaaat caggataaga
    12841 aaacgttaaa aagaatcaat aaactaatca aggatattca acgtgatccc tttacaggaa
    12901 taggtaaacc agaaccactc aaatatgatt accaaggagc ctggtcacgg cgtattgatg
    12961 cagaaaatcg cttgatttat atgatggatg gagatagcgt ggctttcttg tcctttaaag
    13021 atcattacta agtctattga aaggtaggct ttttctcaag tctctactaa actactattt
    13081 ctaaacaaca agtttatttt tgcaaatgtg ttccaaattc cccaaaacat attctatttt
    13141 aggtttgtga aaatcacttt tttatggtag aatgtaaaag aatgtatgtc attcggaata
    13201 acaataaaat gaggtaaaaa catggaaatc atgtcgcttg cgattgctgt ttttgccgtc
    13261 atcattggtt tagtcattgg atatgtcagc atctcagcta agatgaaatc atctcaggaa
    13321 gctgcagagt tgatgctttt aaatgctgaa caagaagcaa ctaatttacg tggacaagct
    13381 gagcgtgaag cggatttact tgttaatgaa gccaaacgtg aaagcaagtc tcttaaaaaa
    13441 gaagcactat tggaggccaa agaagaagcc agaaaatacc gtgaagaagt ggacgctgaa
    13501 ttcaaatcag aacgtcaaga actcaaacaa atcgaaagtc gtttgacaga gagagctact
    13561 agccttgacc gtaaggacga caatttgacg agtaaagaac aaacacttga acaaaaagaa
    13621 caaagtattt ctgatagagc gaaaaacctt gatgcgcgtg aagagcaatt agaggaagtc
    13681 gaaagacaaa aagaagcaga actagagcgt attggtgctc tgtctcaggc agaagcacga
    13741 gatattatct tggctcagac agaggaaaac ttgaccaggg agattgccag tcgcattcgc
    13801 gaagctgagc aagaggtcaa ggaacgttct gacaaaatgg ccaaggacat cttggttcaa
    13861 gctatgcaac gtatcgctgg tgaatatgta gcggagtcaa caaactcaac ggttcatctg
    13921 ccagacgata ctatgaaggg acgcattatt ggtcgtgaag gtcgtaacat tcgtaccttt
    13981 gaaagtttga caggggtcga tgtgattatc gacgatacac cagaagtggt gaccttgtca
    14041 ggatttgatc cgattcgtcg tgagattgcc cgtatgacta tggaaatgtt gctcaaagat
    14101 ggtcgtatac atccagctcg tatcgaagag ttggttgaga aaaaccgtca agagattgac
    14161 aataagattc gtgaatacgg tgaggctgct gcctatgaaa ttggtgcgcc aaaccttcat
    14221 ccagacttga tgaagattat gggacgtttg cagttccgta cttcatatgg acaaaatgtt
    14281 ttgcgccatt cgattgaggt tgctaagttg gctggtatca tggcgagcga acttggtgaa
    14341 aatgcggctc ttgcccgtcg tgctggattc cttcacgata tcgggaaagc cattgaccat
    14401 gaggttgaag gtagccacgt tgaaatcggt atggaattgg cccgtaagta caaggaaccc
    14461 ccagttgtgg tgaatacgat tgctagtcac cacggagatg ttgaagctga gagcgtgata
    14521 gcagttatcg tcgctgcagc agatgccttg agcgcagccc gtccaggtgc tcgtagtgag
    14581 tctcttgaaa gctacatcaa gcgtctccat gatttggaag aaattgctaa cggctttgaa
    14641 ggagtgcaaa ctagctttgc ccttcaagca ggacgtgaaa ttcgtatcat ggtcaatcca
    14701 ggaaaaatca aggacgacaa agtcacaatc ttggctcaca aagttcgtaa gaaaattgaa
    14761 aacaatctcg attatccagg aaatatcaag gtaaccgtga ttcgcgagct tcgtgcagta
    14821 gattatgcta aataaataag aaagagcagt tgaaaaatta ctgctttttt gttacactag
    14881 atagaaagac tgtaaaggat aatctggctt tttgccatta ttctagagaa atgttatttc
    14941 acagattgac taaaaggaga cacaatggca gaccgaggct tactaatcgt tttttctggt
    15001 ccttcagggg ttggaaaagg aacggttaga agagagattt ttgagagttc tgaaaaccaa
    15061 tttcaatact ctgtatcgat gacgacacgc gcacaacgtc ctggagaagt ggacggtgtc
    15121 gactatttct tccgtactcg tgaagaattt gaagagctga ttcgtcaagg acagatgttg
    15181 gaatacgcag aatatgtcgg taactactat ggaactcctc tgacctatgt caatgaaacc
    15241 ttggacaagg gaatcgatgt tttccttgaa attgaagttc agggtgctct tcaggtcaag
    15301 aaaaaggttc cagatgctgt ctttatcttc ctgacaccac cagatttgga tgaattgcaa
    15361 gatcgcttgg taggtcgtgg aacagatagt gcagaagtga ttgcccaacg aatcgaaaag
    15421 gccaaggaag aaattgccct catgcgtgag tatgattatg ccattgtcaa cgatcaggtg
    15481 cccctagctg ctgaacgtgt caaatgtgta attgaagcag aacacttctg tgtggatcgt
    15541 gtcattggtc actatcagga gatgttacca aaatctccaa ctacccgata aaatttagaa
    15601 aataggtaca agcaaatgat gttaaaaccc tctattgata ccttgctcga caaggttcct
    15661 tcaaaatatt cactcgtaat cttggaagca aaacgtgccc acgaattgga agcaggtgcc
    15721 ccagcaactc aaggtttcaa gtctgaaaaa tcaactcttc gcgctttaga agaaatcgaa
    15781 tcaggaaacg ttacaattca cccagatcca gaaggaaaac gcgaagcagt gcgtcgccgt
    15841 atcgaagaag aaaaacgccg caaagaagaa gaagaaaaga aaatcaaaga gcaaattgct
    15901 aaagaaaaag aagatggtga aaaaatttaa ggttgggggg actcaatctt attttttcta
    15961 ttgcaagaat gtactgacaa ggaggaggtg agaagatggc cctagctaag attatcgtag
    16021 atgtgccctt gatgcagacg gaccagccct atagttacag gattccggag gaatttgagg
    16081 gaatgctgga agttgggatg cgggttcatg tgccttttgg taagggtaat cgcctgattc
    16141 aagggattgt tcttggtttg gagtcccaat cagatggaga agagatggag caagatttaa
    16201 aagatattgc agaggtgctg gatttttctc ctgttctcac gccagaacaa ctctggctgg
    16261 ctgaggagtt acgcaaatct gtcttctcct acaaaatttc tatcctcaag gccatgcttc
    16321 caggatttct gaattctagc tatgacaaga ttctctatcc tctggaaggc ttgagtcagg
    16381 aagaacgagt gcgcctgttt ggttcagaag attcgctagc cttttcttca ctagaccttg
    16441 ccaagcaagc tgaaatgatg cgtttgacta gaaaaggcct gcttggtctg gaatatcagg
    16501 cagtcgatca aaagaaggtc aagacccagt cttggtatga ggttgaccat gctcaattag
    16561 aaggtgttga gatttctaca cgtgccaaga aaaagttgga actgagagat tatctgctgt
    16621 ctcatccaga gagcgcttcc ttggctagct tgttagagtc ctactcgcga gagcaagtca
    16681 acttctttgt ggatcaaggt gctgttacca tagtccaaaa ggaagttcaa cgctcggctg
    16741 cttattttga aggaattgaa gcaagtagac ctttggagtt aaatccagaa caaagacagg
    16801 cgcgtgatgc ggttgtgagt tctattggca gttctcaacc tccctttcta cttcaaggga
    16861 ttacaggaag tgggaagacc gaggtttact tgcagattat ccaaggtgcc ctggataagg
    16921 gcaagacagc tattttgctg gtacctgaga tttccttgac tcctcagatg accgagcgtt
    16981 ttatagcacg ttttggggac aaggtagcca ttcttcactc aggattatcc aatggtgaaa
    17041 agtatgatga atggcgcaag gtggagcgtg gcgatgccca agttgttgtt ggtgccagat
    17101 ctgctatctt tgctcctctg aaaaatctgg gtgtcatgat tattgatgaa gagcatgaag
    17161 cggcttataa gcaggacagc aatccccgtt accatgccag agaggtagct attttacggg
    17221 ctcagtataa tcaagcaact ctggtacttg gatctgcaac gccgagctta gagagccggg
    17281 cacgtgctgg caaaggcgtc tatcaacact tacgtctaac ccaacgtgcc aatcctttgg
    17341 ctacaatccc tgaggttcaa gtgattgact ttcgagacta tatcggacaa aatgagacgt
    17401 caaactttac gcctcctttg ctagaggcta tccaagaccg tctggttaaa aaagagcagg
    17461 tggttctcat gctcaatcgc cgtggttatt ctagctttgt catgtgtcgg gagtgtggga
    17521 cggtggatac ttgtcccaac tgcgatattt ctctgacctt gcatatggat accaagacta
    17581 tgaactgcca ttattgtggt ttctcgaagg atattcctca ggtctgtcct aactgtaaga
    17641 gccacagtat tcgttactat gggacgggaa ctcagaaggc ttatgatgag ctagcagaac
    17701 tctttcccca agttcgcatt ttgaggatgg atgtggatac gactcgaaag aaaggcagtc
    17761 accaagcctt gcttgaccag tttgggcgag gggaagcgga tattttactt ggtactcaga
    17821 tgattgcaaa gggtttggat tttcccaatg ttaccctagt aggagttcta aatgcggata
    17881 cggccttgaa tctgcctgat ttccgttctt ctgagagaac cttccagctc ttgactcagg
    17941 tggcaggtcg agcaggtcgg gctgaaaaag caggtcaagt cttgatacag tcctacaatt
    18001 cgcagcacta tgctattcga tttgccaagg atcaagatta cgaaggcttt tatgcctatg
    18061 aaatgggaat cagacgacaa ctcggctatc caccttacta tttcacgatt ggtattaccc
    18121 tttctcacaa gaaagaagaa gaggttttca aacgtgccta tgaagtcatg aacattttgc
    18181 ggtcaggctt gtcagagacc agtcccattc tggggccaac gccaaaaccg attgcccgta
    18241 cccgcaacct ctatcattac cagattttaa ttaaataccg tttagaagat gagctggggc
    18301 cgaccctcaa ccaggtcttg gccttgactc aagaacggga aaatagtgag ctccgtctca
    18361 gcattgacca tgagccgcag caatttttat aagaaggaga agatatgaca aaactaatct
    18421 ttatggggac ccccgacttt tcagcaacag tcttaaaagg acttttgaca gatgaccgtt
    18481 acgaaattct agccgttgtg acccagccaa accgtgctgt tggtcgtaaa aaagttatcc
    18541 aagaaacccc agtcaagcag gctgccaagg aagcaggact atctatctac caacctgaaa
    18601 aattatctgg aagtccagag atggaagatc ttatgaagct aggagcagat ggaattgtga
    18661 ctgctgcttt tgggcagttt ctcccaagca aactccttga tagcatggac tttgctgtca
    18721 acgttcatgc ctccctcctt cctagacacc gtggtggtgc gcctatccat tatgccttga
    18781 ttcaagggga tgaggaagct ggtgtgacca tcatggaaat ggttaaggaa atggatgcag
    18841 gagatatgat ttctcgtcgc agcattccga tcacagatga ggacaatgtt ggcaccttgt
    18901 ttgaaaaatt ggcgctagtt ggtcgtgatt tgcttttgga cactctgcct gcctatattg
    18961 ctggtgatat caaacctgaa ccgcaggata cgagtcaggt taccttctct ccaaatataa
    19021 agccagagga agaaaaactg gactggaaca aaaccaatcg tcaactcttt aaccaaattc
    19081 gtggaatgaa cccctggcct gttgcccata ctttccttaa gggcgaccgc tttaagattt
    19141 atgaagccct accagtagaa ggtcagggaa atccaggtga gattctctct atctgcaaga
    19201 aagaattgat tgtcgcaacg gctgaagggg ctctatccct caaacaagtg cagccagctg
    19261 gtaagcctaa gatggacatt gcttccttcc tcaacggagt tggacgtaca ttgactgtag
    19321 gagaacgatt tggtgactaa agtagaaacg gctagaagtt tagctctagc agtgctagag
    19381 gatgtttttg tgaatcaagc atattcaaat attgccttaa ataaacacct caaggggagt
    19441 cagctctctg cagcagacaa gggcttagtg accgagctag tctatggaac ggtagccctt
    19501 aaactgactc tggaatggta cctatcccac tttatcgaag acagagacca gttagacagc
    19561 tggctctatg tccttcttct catgagtgcc taccaactcc gctatttgga caagattcca
    19621 gatcatgctg tggtcaatga agcagtggaa ttggccaaac tccgtaaaaa aggcagtgaa
    19681 aaattggtca acgctgtcct tcgccgtatc ttgcgtgaag gctggccaga tattgctagc
    19741 atcaagcgaa aaaacaagcg tgactccatt gcctattctc tcccagtttg gctagttgcc
    19801 aaactcaagg aagaatacgg agaggagaga gcaaaagcca tctttgaaag cctgttagtg
    19861 cgaaacaaag ccagtattcg tgtaacagac ctaagtcgaa aagaggaaat ccaagccttg
    19921 ttggaggcga ataattccct tttagcaacc actggtctgg ttaaggagca ggggcatttt
    19981 gcagggcata atttgtttgc gaatggagcc attaccatcc aagatgagtc cagtcagctg
    20041 gttgctccga cgcttgattt acaaggtgat gagcgagtgc ttgatgcctg tgcggctcca
    20101 ggtgggaaaa cagcccatat agcctcttat cttacgacag gtcaggttac tgctctggac
    20161 ttgtacgacc acaagttgga tttaattcaa gaaaatgccc aacgtctggg agttgcagat
    20221 cgggttcaaa ctcaaaaatt ggatgccaga aaggtgcatg agttttttga ccaggattcc
    20281 tttgataaga ttttggtgga tgctccttgt tcaggaatcg gtcttttgcg ccgaaaacca
    20341 gatatcaaat acaataaaga aacggcagat ttcgcgtcct tgcaggaaat tcagttagaa
    20401 atattaggta gtgtttgtca aatactaggc aaaggtggta taataactta tagcacctgc
    20461 actatcgtct cagaggagaa ttttcaagtc gttaaggcct ttttagagag tcatcccgag
    20521 ttcgagcagg taaaactaga acatgaatgt aaggatatca tgaaagacgg ctgtatcctc
    20581 attacacctg aattgtatgg aagtgatgga ttcttcatca gtcaatttcg caagatatcg
    20641 gattaggaag gaactgacac atggaaattt cattattaac agatgttggt cagaaacgaa
    20701 caaataacca agactatgtc aaccactatg tcaatagagc tggacgtacc atgattattt
    20761 tagctgatgg gatgggaggt catcgcgcag ggaatatcgc tagtgaaatg gcggtcacag
    20821 acctgggtgt agcttgggtt gatacccaga tcgatacagt caatgaagtg cgtgaatggt
    20881 tcgcccatta cctagaaatt gaaaatcaaa agattcacca gcttggtcag gatgaagctt
    20941 acagaggcat gggaactact ttggaagtcc ttgctattat tgataatcag gctatctatg
    21001 ctcatattgg tgattcgcgt atcggcttga ttcgtggaga agaataccat cagttgacga
    21061 gtgatcattc tttggttaat gaattgctca aggctggtca attgacacca gaagaggcag
    21121 aagctcatcc gcaaaaaaat attatcaccc agtctattgg gcaaaaagat gaaattcagc
    21181 ctgattttgg gacagttatc cttgagtcag gtgactatct cttgctcaat agtgacggct
    21241 tgaccaacat gatttcaggc agtgagattc gtgatattgt aaccagtgat attcctttag
    21301 cagataaaac ggagacactt gttcgttttg ctaacaatgc aggaggttta gacaacatta
    21361 cggttgccct tgtttctatg aacgaggagg atgaagaatg atccaaatcg gcaagatttt
    21421 tgccggacgc tatcggattg tcaaacagat tggtcgagga ggcatggcgg atgtctacct
    21481 agccaaagac ttaatcttag atggggaaga agtggcagtg aaggttctga ggaccaacta
    21541 ccagacggac ccgatagctg tagctcgttt tcagcgtgaa gcgagagcta tggcagatct
    21601 agaccatcct catatcgttc ggataacaga tattggtgag gaagacggtc aacagtatct
    21661 tgcaatggag tatgttgctg gactagacct caaacgctat atcaaggaac attatcctct
    21721 ttctaatgaa gaagcagtcc gtatcatggg acaaattctc ttggctatgc gcttggccca
    21781 tactcgagga attgttcaca gggacttgaa acctcaaaat atccttttga caccagatgg
    21841 gacggccaag gtcacagact ttgggattgc tgtagccttt gcagagacaa gtctgaccca
    21901 gactaactcg atgttgggct cagttcatta cttgtcacca gagcaggcgc gtggttcgaa
    21961 ggcgactgtg cagagtgata tctatgccat ggggattatt ttctatgaga tgttgacagg
    22021 ccatatccct tatgacgggg atagcgcggt gaccattgcc ctccagcatt tccagaaacc
    22081 cctgccgtcc gttattgcag aaaatccatc tgtacctcag gctttagaaa atgttattat
    22141 caaggcaact gctaaaaagt tgaccaatcg ctaccgctcg gtttcagaga tgtatgtgga
    22201 cttgtctagt agcttgtcct acaatcgtag aaatgaaagt aagttaatct ttgatgaaac
    22261 gagcaaggca gataccaaga ccttgccgaa ggtttctcag agtaccttga catctattcc
    22321 taaggttcaa gcgcagacag aacacaaatc aatcaaaaac ccaagccagg ctgtgacaga
    22381 ggaaacttac caaccacaag caccgaaaaa acatagattt aagatgcgtt acctgatttt
    22441 gttggccagc cttgtattgg tggcagcttc tcttatttgg atactatcca gaactcctgc
    22501 aaccattgcc attccagatg tggcaggtca gacagttgca gaggccaagg caacgctcaa
    22561 aaaagccaat tttgagattg gtgaggagaa gacagaggct agtgaaaagg tggaagaagg
    22621 gcggattatc cgtacagatc ctggcgctgg aactggtcga aaagaaggaa cgaaaatcaa
    22681 tttggttgtc tcatcaggca aacaatcctt ccaaattagt aattatgtcg gccggaaatc
    22741 ttctgatgtt atcgcggaat taaaagagaa aaaagttcca gataatttga ttaaaattga
    22801 ggaagaagag tcgaatgaga gtgaggctgg aacggtcctg aagcaaagtc taccagaagg
    22861 tacgacctat gacttgagca aggcaactca aattgttttg acagtagcta aaaaagctac
    22921 gacgattcaa ttagggaact atattggacg gaactctaca gaagtaatct cagaactcaa
    22981 gcagaagaag gttcctgaga atttgattaa gatagaggaa gaagagtcca gcgaaagcga
    23041 accaggaacg attatgaaac aaagtccagg tgccggaacg acttatgatg tgagtaaacc
    23101 tactcaaatt gtcttgacag tagctaaaaa agttacaagt gttgccatgc cgagttacat
    23161 tggttccagc ttggagttta ctaagaacaa tttgattcaa attgttggga ttaaggaagc
    23221 taatatagaa gttgtagaag tgacgacagc gcctgcaggt agtgtagaag gcatggttgt
    23281 tgaacaaagt cctagagcag gtgaaaaggt agacctaaat aagactagag tcaagatttc
    23341 aatctacaaa cctaaaacaa cttcagctac tccttaaaag cagatggata atcaaaatga
    23401 gtaatcaatc tttgtcatga tttcatggca aagatttttt ttgagtccag atttgtgata
    23461 gaatagaggg agttgataaa aggaggaaag catggaagaa tcaaaagaat taaatgccgt
    23521 cattgatgtg attatgctag cggggactat tctccttaaa agtggctcag aaatccatcg
    23581 tgtagaagat accatgattc gaatcgcgca ttcgcagggg attgtggatt gcaatgtcct
    23641 tgccatgcct gccgctatct ttttctctat tgaaaatacc aatatttcgc gcatgaagcg
    23701 cgtgacctcc tcttcttata acatcgaaaa agtctgcgat gtgaaccaga tttctcgtca
    23761 gctagttggg gggcagattg acttagaaac agcctttaag caattgacgg ccttgcaagc
    23821 tcaacccctt ccctatacta agttgcaggt aactctggct gcgaccttta gtgctccttt
    23881 cttttcagtt atgtttagcg gaaatatcta cgacgcactt ggtgcaggag tggcgacctt
    23941 atttggtttt gccttttccc tctatgtgga aaaatttatc cgaattccct ttgtgacagc
    24001 ctttgctgga gcctttgtct ttgggataat tgcccagttt tgggctcgct acacaggttt
    24061 tccttcaacg gcagatttga ttatagctgg tgcggtcatg ccgtttgtac caggtattgc
    24121 cttgaccaat gcggtccgtg atattatgac caaccacata aactctggta tgagtaagat
    24181 gtttgaatcc ctgctcatta ccctcgcttt aggggcagga acttctgtcg ccttggtatt
    24241 gatgaactaa tatgacacta acaacctttt tattacaagc agtagcaagt tttcttgcca
    24301 ttatcacttt tttaatcgta ctcaatgtgc aacggtctat gctcttacct ggagggattt
    24361 tgggcatgac tgtctggcta atctatctct tgctcaagga accgaccaat gtcattgtag
    24421 ctaccttcat tgcagccatt attggttctt gtgtcagcca gattttaagt attctttata
    24481 agacacctgc tgtggtcttt atcttggcca ttttggcacc gctggttcca ggttatctct
    24541 cctaccgaac aactgccttt tttgtgacag gggactataa taaagcactg gcaagtgcga
    24601 ccttggttgt catgttggct ttggtaatct ctattggaat ggctagcgga acagtgattc
    24661 tcagactgta tcattatata aaaacacatc gagtatcgta gactttacag aaataaaaga
    24721 attttctgaa aaatgagata aataaattaa caacgctttc tatatgtgcg agaataccgc
    24781 acttatgaag aaattgcgac tgattttggt atccacgaaa gcaacttact ccgtcggagc
    24841 caatgggttg aagtaactct tgttcaaagg tggtgttacg atttcaagaa ctcctctcag
    24901 ttctgaagac acggtaatga ttgatgcgac ggaagtaaaa atcaatcgcc ctaaaaaaaa
    24961 caattagcga atgattctgg taaaaagaaa tttcacgcta tgaaggctca agcgattgtc
    25021 acaagtcaag ggagaattgt ttctttggat atcactgtga actattgtca tgatatgaag
    25081 ttgttcaaaa tgagtcgcag aaatatcgga caagctggta aaatcttggc tgacagtggt
    25141 tatcaagggc tcatgaagat atatcctcaa gcacaaactc cacgtaaatc cagcaaactc
    25201 aagctgctaa cagttgaaga taaagcctat aaccatgcgc tatctaagga gagaagcaag
    25261 gttgagaaca tctttgccaa agtaaaaacg tttaaaatgt tttcaacaac ctatcgaaat
    25321 catcgtaaac gcttcggatt acgaatgaat ttgattgctg gcattatcaa tcatgaacta
    25381 ggattctagt tttgcaggaa gtctactact ttccttattg tctgtaaatc tactgacctt
    25441 gttgtttatc ccagtcatgg tttctagttc gggctcagag tttcaaagtg gatggcaaga
    25501 gcatcaattg attgctgaga aggttagtaa aacacttgat aagacatttg ataaggatgt
    25561 cagagaaatt ccgaccagtc agttttatca aaaatttgta gatgagatgg gaaggactta
    25621 ctcaggaaat ttgatcctcc aggagctgat aactgtgaat ggagcttata aagctactta
    25681 tatcggtgaa ctctctagca actaatcatt ctttaaaatg atgaccaata agaggcttga
    25741 tttggtgaat caagtctttt ttctctcttt tactgccatt tgtgataaaa tagtatagaa
    25801 cgatttttta catgaatgat aaaacagagg taaatatgac aatcggtatt gataagattg
    25861 gttttgcgac cagtcaatat gtcttgaaat tacaagactt agcagaagcg aggggaattg
    25921 accctgaaaa attaagtaaa ggactcttac tcaaggaatt gagtattgcg cccctaactg
    25981 aggacatcgt gaccttggcg gccagtgcta gtgactctat tttaactgag caagaaagac
    26041 aagaagttga catggtcatt gtggcgaccg agtcaggaat tgaccagagt aaggctgcgg
    26101 ccgtctttgt gcatggcttg ctgggcatcc agccctttgc tcgtagtttc gagattaaag
    26161 aagcctgcta tggggcgact gctgccctcc attatgccaa attgcatgtg gaaaattctc
    26221 cggagtccaa ggtcttggtc attgcaagtg atattgccaa atacggtatt gaaactccgg
    26281 gagaacccac tcagggtgcc ggaagtgtgg ctatgttgat tacacaaaat ccacgcatga
    26341 tggcctttaa taatgacaat gtagctcaga cccgtgacat catggatttc tggcgaccaa
    26401 attactcgac aactccttat gtaaatggtg tctattctac ccaacaatac ttggatagtt
    26461 tgaaaacgac ttggcttgaa tatcaaaaac gctaccagct tactttggat gattttgcgg
    26521 ctgtttgttt ccacttgcct tatcctaaat tagcgctaaa aggcttgaaa aaaatcatgg
    26581 ataagagcct gcctcaagag aaaaaagacc tcttacaaaa gcattttgac cagtctattc
    26641 tctacagtca aaaggtgggg aatatctaca caggttcact tttccttgga cttttgtctc
    26701 tcttggaaaa tacagatagc ttgaaagctg gggataaaat cgccctttat agttacggaa
    26761 gtggagctgt ggctgagttc ttcagtggtg aattggttga aggatatgaa gcttatttgg
    26821 ataaagaccg cttgaacaag ctcaaccaac gaactgtctt atccgttgca gactatgaaa
    26881 aggtcttttt tgaggaagta aacttggatg aaacaaactc tgcccagttt gctggctatg
    26941 aaaatcaaga ttttgccttg gttgaaattc tcgaccacca acgccgttat agcaaggttg
    27001 aaaaataatg aagataagtt ggaatgggtt ttctaaaaaa tcataccaag agcgcctcga
    27061 gctgttaaaa gctcaggcgc tccttagtcc tgagagacaa gctagtctgg agaaggatga
    27121 acagatgagt gtgactgtgg cagaccagct gagtgagaat gtagtgggaa ctttttctct
    27181 gccttattcg ctggttccgg aggtacttgt caacggtcag gaatacaccg ttccctatgt
    27241 gacagaagaa ccctctgtgg ttgcggcggc cagctatgcc agcaaaatca tcaagcgtgc
    27301 aggtggtttt actgcacaag tccatcagcg ccagatgatt gggcaggtag ccctttatca
    27361 agttgctaat cctaaactag cgcaagagaa gattgccagc aagaaagcgg agctcttgga
    27421 gcttgccaat caagcctatc cttctatcgt taaacgtggg ggtggggcgc gtgacctgca
    27481 tgtcgagcag ataaaaggcg aaccagactt tctcgttgtt tatattcatg tcgataccca
    27541 ggaagccatg ggtgccaata tgctcaacac catgctggaa gccttgaaac cagtcttaga
    27601 agaactcagt cagggacaga gtctcatggg aatcctgtcc aactacgcga ccgattctct
    27661 ggtgactgca agctgtcgca tggcctttcg ctacttgagc cgccaaaagg atcaaggacg
    27721 agagattgcg gagaaaattg cgttggctag tcagtttgcg caggatgatc cttaccgagc
    27781 tgctactcat aataaaggaa tttttaatgg tattgatgcg attttgattg ccactggtaa
    27841 tgactggcgt gccatcgaag ctggggccca tgcctttgcc agtcgagatg gacgctatca
    27901 aggtcttagt tgctggacgc tggaccttga aagagaagaa ttggtcggtg agatgaccct
    27961 gcccatgcct gtagcgacta agggtggctc tatcggcctc aacccacgtg tagctctcag
    28021 tcatgatcta ctaggaaatc cttctgccag agaattagcc cagattatcg tgtctatcgg
    28081 tcttgcccaa aattttgcag ccctcaaagc cttggtaagt acgggcatcc agcaaggcca
    28141 catgaaacta caggccaaat ccctagctct cctagctggg gctagtgaat ctgaagttgc
    28201 tcccctagtc gagcagctta tcgcagataa aacctttaac ctagagacag cccagcgcta
    28261 tctcgaaaat ttaagatcat aaaaaactca gacgaatcgg tctgagtttt cttgtgttta
    28321 aatacttttt cctggtaata gtgtaactgg taagaagtaa ccagttgtgg tgacttcctt
    28381 gccttcaatc ttttgcaaga gaagatcaat agtgagacaa gcaatctctt ccaaaggttg
    28441 cttgatagta gccaattgag ggtagtaatt ttcgataaag taggtcccat catagccgat
    28501 gaccttgagc tcttttggga cagaaatgcc caattcttga gcgattttaa tgaccagaat
    28561 agctgtcaaa tcatccgaag caaaaatggc atctggtttt tcccgggtca agatattctt
    28621 gatttccatt tcttttctga cgggagaaaa gtcactggaa acattgataa taggagcttt
    28681 tgggagtacg gatgcaaaac cagcgtggcg cagtccggtt ggcgaattgg aattgtcatt
    28741 ccctgtaatc atgatgatag actgggcacc tgtcttgacc aaggtttggg cagcaagaac
    28801 cccaccagca tagttgtcag aggagacgac agggatgtct ggcgataggt ttcggtcaaa
    28861 ggaaataatc ggcgctgtca cacgattgta gtcttcgatt cctaggttgt gactaccaga
    28921 aatgatgccg tccacctgat tggcttccaa catttcgatg tattcacgtt ccttctcaga
    28981 atcatgttca ctgttgcaga tgatggtctt gtaaccattt ttgaagagtt ggtgttccaa
    29041 tttatcaatc aattctgcat agaaaacatt ggaaatattg gggaaaatca agccgattaa
    29101 cttagctgat tttccttgca gactacgagc caggttgttg ggtttatagc ccaattctcg
    29161 catggcttca ttgacttttt ggatggtttt ctcagataga tacccttttt tattgataac
    29221 ccgagaaacg gtagtaggac tgacgcctgc aagtttggcg acatcagtta gttttgcgac
    29281 cataatctaa ttcatagtaa gttccagttg ggtttccaga tttgatcagg ataccatttt
    29341 ggtccgcatg tgggaagaca cgaccagaaa atactttttc tcctttattg atgaaaattt
    29401 caaagacaga gttatcgatg aagattgtag cagtagtagc ctgattctcg atagggcaag
    29461 aacgagttgt cccaaattct tgggcatact gttctccagc ctggctacga tccactgtca
    29521 cttgaccgtt tacaaggtca aagttgattg aaagtccctt accttcttta tcagcaagta
    29581 agacaatctc gctctggcta ttagcttcca agttgagttc aagttcgtaa gtgttcttgg
    29641 tttgggaacg gtttgagaag gcttcttcag aagcacgaag gtccttaata gcagcgactg
    29701 gatactggta gagcttgtcg tctttgatag tgagttcctt gaccaaagag aaggttcctt
    29761 ggtggtcaaa acggtcagat gggtaagaaa catctggcaa accaagccag ctaactgcta
    29821 gagcacgccc atcaggagcg ttgaaggctt gagttgcata ggcttcgaaa ccgtaatcca
    29881 tgttttgaag ttgagacaca tctaccattt tggcattttt agggtcaaag gaagccccaa
    29941 tcttatacat atttggaaag atattatcgt agtctagaac tttcttatcc aatccttgtg
    30001 gacagtagag aaggacaggt tgttcctcta caaagaccag attaggacat tccatcatgt
    30061 aggcagtacg gtcgttagca aagtcaaggt cgccaactgc ttgccagttt gtgtagtcgt
    30121 tattgacagc cttgtagaga cgaacgaaac cttttttctc caagtcctgt ccaccgacga
    30181 cagcatagta ttgaccttta aagttaaaaa tttgtggatc gcggaagtgg tcagtagagt
    30241 ctgctggctg gtcaatcaag atcttgtcaa tctttgtaat cttaccctcc ttgtccatca
    30301 aagcaccgat ctggtatggg tgacggatcc agttttcatc gcgaacattt cctgtataaa
    30361 ataggaataa gttatcgcca aattgcatgg cagaaccaga gtaggcaccg tggctatcta
    30421 atggagtatc tggtaaaact ttgattccag tttctttaaa gtgaaccaaa tcatcacttt
    30481 ctagctgtgc ccaagatttt aaaccgtggg ctgcaccaaa aggaaaattc tggtaaaaga
    30541 ggatccactt gccatcaaag taagaaaagc catttgggtc gttgagaagt cctgtttttg
    30601 gctcaacatg gtaatgagta tgccatggag attgtgccat attttccttt atatgttgaa
    30661 tttcttcttg cgtccaatct tgataaagtc tgtaacgacg ctcagttgtc cattccattc
    30721 attcctccaa aaatcttatc acttttaata gtaactgttt tcgataaaaa atgcaagcct
    30781 tttatgttaa aaaagaggaa aaactgtcaa aggattatca taaaataaat acaggaaatc
    30841 aatcaaattt ttacgaaaat gtgaaagata atgaaataaa agacttttta accaaggttt
    30901 caaacttatt tttcaaggaa ttcctgatga aacagtcaaa aacaatcaat ctaaagcttg
    30961 cccactaagt ggatagaata tttttctgca aaacgcttga catattttta aaacatgata
    31021 aaataatagt cgtaagggcg aataaaatcg ctttcaaaca agaacaaaat gttatataag
    31081 gagatttttg caaatgaaca atcaggaaat tgcaaaaaaa gtcatcgatg ccttgggcgg
    31141 acgtgaaaat gtcaatagtg ttgcccactg tgcgactcgt ctacgtgtca tggtcaaaga
    31201 tgaagagaaa atcaataaag aagtgattga gaacttggaa aaagttcaag gtgctttctt
    31261 taactcaggg caataccaaa ttatctttgg tacaggtaca gttaacaaaa tgtacgatga
    31321 agttgttgta cttggcttac caacatcatc taaggatgac atgaaagcag aagttgctaa
    31381 acaagggaac tggttccaac gtgctatccg tacttttggt gatgttttcg ttccaatcat
    31441 cccagttatc gtagcgacag gtctcttcat gggtgtgcgt ggtcttttca acgctcttga
    31501 aatgccactt ccaggtgact ttgcaactta cacacaaatc ttgacagata cagccttcat
    31561 catcttgcca ggtttggttg tgtggtcaac cttccgtgta tttggtggaa atcctgccgt
    31621 tggtatcgtt cttggtatga tgcttgtctc tggctcactt ccaaacgctt gggcagttgc
    31681 tcaaggtggt gaagtaacag cgatgaactt ctttggtttc atccctgttg ttggtttgca
    31741 aggttccgtt cttccagcct tcatcatcgg ggttgtcgga gctaaatttg aaaaagctgt
    31801 ccgcaaggtt gttccagatg tcattgacct cttggtaaca ccattcgtga cacttttggt
    31861 catgtctatc cttggactct ttatcattgg accagttttc cacgttgttg aaaactacat
    31921 ccttattgct acaaaagcga ttcttagcat gccatttggc cttggtggtt tcttgattgg
    31981 tggggttcac caattgatcg tcgtgtcagg tgtgcaccac atcttcaact tgcttgaagt
    32041 gcaattactt gctgctgacc atgctaaccc attcaacgct atcatcacag ctgctatgac
    32101 agctcaaggt gctgctactg ttgcggttgg tgttaaaaca aaaaatccaa aactgaaaac
    32161 acttgctttc ccggctgctc tttctgcctt cctaggtatt acagagcctg ctatcttcgg
    32221 ggtgaacttg cgcttccgta aaccattctt cctttcattg attgctggtg caatcggtgg
    32281 tggattggct tctatccttg gacttgctgg tactggtaat ggtatcacca tcatccctgg
    32341 tacaatgctt tatgttggta acggacaact tccacaatac cttcttatgg tagctgtatc
    32401 atttgccctt ggttttgctc ttacttacat gtttggttac gaagatgaag tagacgcaac
    32461 tgcagctgca aaacaagctg aagtggctga agaaaaagaa gaagttgcgc cagcagctct
    32521 tcaaaatgaa acacttgtaa ctcctatcgt cggtgatgtt gtcgctcttg ctgatgtcaa
    32581 tgacccagtc ttctcaagtg gagctatggg acaaggtatc gctgtgaaac caagccaagg
    32641 cgtggtctat gcaccagctg atgctgaagt ttcaattgcc tttccaacag ggcacgcttt
    32701 tggtttgaaa acaagaaatg gtgctgaagt tttgattcat gttggtattg atactgtatc
    32761 tatgaacggt gacggttttg aaacaaaagt tgctcaaggt gataaggtga aagttggcga
    32821 tgttcttgga acatttgact caaacaaaat cgctgcagct ggacttgatg atacaacaat
    32881 ggttatcgtt acaaatacag gtgactacgc ttcagtagct ccagtcgcaa caggttcagt
    32941 tgctaagggg gatgctgtga tcgaagtgaa aatctaatca atcctctcta atgtgaaaac
    33001 gaacaaatga catatttgtt cgtttttatt agatagtaag atttacagag gaaaatctaa
    33061 aaaatagaga catttagact ttcgaagtat gctataataa agaaaataaa aacaagaggt
    33121 ttatcatgac aaaattatat ggaagcttgg aagcgggcgg tacaaagttt gtctgtgctg
    33181 tcggtgatga aaactttaac gttgtagaaa aaacacaatt tccaacaaca actccaatcg
    33241 aaacaatcga taaaaccatt gagttcttct caaaattcga taaccttgct ggtcttgcag
    33301 ttggttcatt tgggccgatt gatattgaca aaaactcaaa aacttatggc tttatcacga
    33361 cgactccaaa accaaactgg gcaaatgtgg acttgcttgg tgcccttcgt cgcgccctaa
    33421 atgtgccaat gtacttcaca acagacgtaa acagctctgc ttacggtgaa gtggttgccc
    33481 gtaacaatgc tggtggtcgt atcgaaaact tggtttacta cacaatcggt acaggtatcg
    33541 gtgcaggtgt catccaacgt ggtgagttta tcggtggtgt gggtcaccct gaaatgggtc
    33601 attattatgt tgctagacac ccaatggata ttgaaaaaga gtttaagggt gtttgtcctt
    33661 tccataaggg atgtctagaa ggttatgcag ctggtccaag tttggaagct cgtacaggtg
    33721 tacgtgggga aactattgaa ctcaacaacc ctgtttggga tgttcaagcc tactatatcg
    33781 ctcaagctgc ggttaatgcg acagtgactt tccgcccaga cgtgattgtc tttggtggag
    33841 gggtcatggc tcaacaacat atgctggacc gtgtccgtga gaaatttaca tctcttctta
    33901 atggttacct accagtacca gatgtgcgtg actatatcgt gacgccagca gtcgcaggaa
    33961 atggttctgc cacacttggg aactttgttc ttgcaaaaga agtttcaaaa taaagcacaa
    34021 aatccgcttg ggaaaccaaa cggatttttt acgtgtcaaa gcatttgcca gaaaaagtca
    34081 ataatatagg tcagaccgta ggtataaacc acgagggtaa agggtttggt cagaatgatg
    34141 atggtcatgt agcgcttgaa actcatcttg gtcagggcag ccagcataca gagaaagtca
    34201 gctgggctaa tgggccaaat catcataaaa ataaagaagc ggtcaaaacg attgccctta
    34261 tctagccagc cgatgtactt gtcgtaggtg cgcttgctga cgacagactg gacaaaggca
    34321 gctccgtata ggcgcactag ataaaagata atggcacagc caatcacgat gccgatatag
    34381 ttgtagatag tcccgatgat gtgcccgtag ataaagaccc cagccaccga ggtcaaggcc
    34441 cctggaatga tagggacgac agtctgtaaa atctgtaaaa agataaagag aggtggaccc
    34501 cagatgcctg cctgctggat aaaggcagag agggtttcct tggattgtaa aatcccagcc
    34561 tgataagccc aaatacagaa aatcaaactc ccaaccccac cgacaatcga tgagatattg
    34621 ataactcgct gcagaagggg agaaacagct ttcatttgtt tatcctgtga catgtaaact
    34681 cctcatagat agtatatttc tactatacca tattttggag gagaaagggg gaatgagtct
    34741 tttttgataa ggaatagaaa gtaaatagcc cttcgagact tagaataggt ctgtcaacta
    34801 aaggttatat gcattctagg tttcgaataa tcgcaattcc ataaatttaa aagtattcta
    34861 agtttcgaat agcttatctg ggataatttt gaggcattcg cgctttcgaa tagtcatttt
    34921 ccctaaagtt tatatgtatt ctgaagctag aaagactaaa atataaaagt agtaagagtc
    34981 tctctctgat ggacgtaatt tatggctagt atgaatcctt tgaattgtta gttaatttta
    35041 atattaatca gttctgaaat aattactaaa tatagttaga tggtgagtta attattgcta
    35101 aatttcaagt tcaagttagt catccagaag tcttctctgg gggacttgta gttcaagcat
    35161 tttttaggat agttgttaat ccacttttcg ataaatgcga cttcctttgt agttgttttc
    35221 ttagttccct gaggtaacca tctatgaatg agcctgttgt gattttcatt agatcctata
    35281 gtgatgtgca taatagatat agcagattga aactagaata gtatacatct acttctaaaa
    35341 cattgttaga aatcaatttg actgtcctga tcaatttgtc ctgtttttat ttcattttac
    35401 tatataatcc ttagaaaaca tatcggacaa gcggttgaat tccgttccgt ccattagtag
    35461 ataaaggatt actccttctt gaaatgacag atgaacttgt ttcttataaa aatgttgtct
    35521 gaaactatta gcctttttcc agaagtttta gaggaagaaa actttacgag gaaaaaggag
    35581 ttactcaaat aacaattcag gattaaaaat agacagttga ggagcggaag gtataaatta
    35641 agtttgctac tgtataatgg atttatcact aatactcttc gaaaatctct tcaaaccacg
    35701 tcagcttcgc cttgccgtag atatagttac tgacttcgtc agttctatcc acaacctcaa
    35761 aacagtgttt tgagctgact tcgtcagttt tatctgcaac ctcaaagctg tactttgagc
    35821 agcctacggc tagcttccta gtttgctctt tgcttttcat tgagtataaa agtgctccag
    35881 gccatatttt acacagcaat agtcttctaa aaatggacaa aaacattgta aaggctatca
    35941 aaaaggagta taatgagtgc aagaaatttc ggaggtgaaa gatgctagaa gtaagaagtc
    36001 tagagaaaag ttttggctcc aagcaagttt tgtttggtat tgactttcaa gcgcgaccag
    36061 gtcgtatttt gggactagtc ggaaaaaatg gtgctggaaa aacaacgatt ttccatagta
    36121 ttttgaaatt cctagaatat cagggagaaa tcggtctgga tggtcaggat attcgtcagg
    36181 agacctatgc tcggattggt tatctgcctg aagaacgcag tctcatgcct aaattgacag
    36241 ttcttgaaca agttcgctac ttggcgactc taaaaggcat ggatgccaaa gaagtcaaag
    36301 aaaaactccc tcaatggatg aagaggttgg aagtgaaagg aaagctgaca gataaaatca
    36361 agagtctgtc aaaaggaaat cagcagaaga ttcagctcat tattactctg attcatgaac
    36421 cagacctgat tatcttggat gagcctttta gtggattgga cccagttaat acagaattgc
    36481 tcaaacaagt catttttcag gaaaaagagc gcggagcaac cattatcttt tctgaccatg
    36541 tcatgaccaa tgttgaggaa ctttgtgacg atattctgat gatccgagat ggccgtgtgg
    36601 tcttgcacgg accagttcag gatgtccgca atcaatacgg gaaaacgcgt ctctttgttt
    36661 caagtgaacg aagcaaggaa gaattggaaa atcttcctca tgtcaaacag gtgagcttga
    36721 ccaaacaagg cagttggaaa ttgattttgg aggatgagag cgctggaagg gaactcttcc
    36781 caatcttgac tcaaggtcaa tatatcgcaa catttgacca acaagcgcca actatcgatg
    36841 aaatctttaa actagaatca ggagtggaag tatgagaaat atgtgggttg taatcaagga
    36901 aacctatctt cgacatgtcg agtcatggag tttcttcttt atggtgattt cgccgttcct
    36961 ctttttagga atctctgtag gaattgggca tctccaaggt tcttctatgg ctaaaaataa
    37021 taaagtggca gtagtgacaa cagtgccatc tgtagcagaa ggactgaaga atgtaaatgg
    37081 tgttaacttc gactataaag acgaagcaag tgccaaagaa gcaattaaag aagaaaaatt
    37141 aaaaggttat ttgaccattg atcaagaaga tagtgttcta aaggcagttt atcatggcga
    37201 aacatcgctt gaaaatggaa ttaaatttga ggttacaggt acactcaatg aactgcaaaa
    37261 tcagcttaat cgttcaactg cttccttgtc tcaagagcag gaaaaacgct tagagcagac
    37321 aattcaattc acagaaaaga ttgatgaagc caaggaaaat aaaaagttta ttcaaacaat
    37381 tgcagcaggt gccttaggat tctttcttta tatgattctg attacctatg cgggtgtaac
    37441 agctcaggaa gttgccagtg aaaaaggcac caaaattatg gaagtcgttt tttctagcat
    37501 aagggcaagt cactatttct atgcgcggat gatggctctg tttctagtga ttttaacgca
    37561 tattgggatc tatgttgtag gtggtctggc tgccgttttg ctctttaaag atttgccatt
    37621 cttggctcag tctggtattt tggatcactt gggagatgct atctcactga ataccttgct
    37681 ctttattttg atcagtcttt tcatgtacgt agtcttggca gcattcctag gatctatggt
    37741 ttctcgtcct gaggactcag ggaaagcctt gtcgcctttg atgattttga ttatgggtgg
    37801 tttttttgga gtgacagctc taggtgcagc tggtgacaat ctcctcttga agattggttc
    37861 ttatattccc tttatttcga ccttctttat gccgtttcga acgattaatg gctatgcggg
    37921 gggagcagaa gcatggattt cacttgctat tacagtgatt tttgcggtgg tagcaacagg
    37981 atttatcgga cgcatgtatg ctagtctcgt tcttcaaacg gatgatttag ggatttggaa
    38041 aacctttaaa cgtgccttat cttataaata gaagagcctt gcgaaagcga ggtttttaaa
    38101 gatgaaaagg atggaatcac gaacctaatt atgtacacat tatgtaaaca ggttgcttga
    38161 aaactcaatt gtatagtgaa ctgaatctgg aataggataa tattacttct aaaacattct
    38221 tataaattga tttgaattcc aaaatcccat cgttccgttc ttatttcatt ttgcgatata
    38281 gtgaaaggaa ataagtcagc tcacaaaaaa cgcataatat caaggatttt taacacttga
    38341 tactatgcgt tttctaattt taaagacttt ttgcctggtc tcttttgttc tatgagtatg
    38401 ttacatatct aggtaaaaat tatttaaagc aaattaacct tatttctcaa gatgtagtag
    38461 gttccgagat aaaagatagc tatgaatatg agttctttaa caatggctat acctgctccc
    38521 atatagaaat ggtcattgag tcctaccagt gaattgacat agaaattaga actaagattg
    38581 aagaaaagtt caataaatcc aatgacgatt tggataccaa tgtaggctgc aacagcgagt
    38641 gctgtacggt attcattgaa aagctgtcca atggaaatag ccaggtagat gcagaggatt
    38701 cctgaaatgg tatttagtag gaaggatata cctgtaagaa agatctgagg gagatgtgtt
    38761 tctacaaatg taatcacata agaaagagga atccattctg gagctgttaa agccagaata
    38821 ataacagcac ttagagccaa tacagcggtg ctaatcaatg accagataaa ggcaccgatt
    38881 agtttggctg tgatgatatg gtgttcagaa actggcaagg tcaaagtcag atagccttgt
    38941 cggtcgtaga cactaccttt gaagcgttta ataatcaaga aaatggttga aatcgcaagt
    39001 gtaagcatca agccaccaaa gactgtagct agaaaaagta gcatagtagc ctgactttct
    39061 tggtaaggta gatttttaaa gccttgtgtc tgtattccga tgagggcaga aaggactagc
    39121 acggctgcgt agagggctaa ataccacttg ttaacatttt taaattcgta gtgaactaaa
    39181 ttccaaaaca taaataatct cctttgctta ggccttaaat tcctgacgga agagttggtc
    39241 aatggattca cctgactcgt agcgaatatc atctacattt ccttgacgga cgacttttcc
    39301 gtcttttagg aagacaattt catccaagat tggctcgata tcagaaatca agtgggtaga
    39361 aatcaaaacg gtagaagttg gtgagtagtt gttgataatg gtattgagga tataagcacg
    39421 ggctgctgga tccaccccac caatgggttc atccaaaaca tagagacgag catcacggct
    39481 cataaccaaa atcagttgaa ccttttcttt gtttcctttt gatagtttct tgagacgact
    39541 attttcatca atgcccaggt ctgcaagtag atgatgagcg cgttcaagat tgaaatcttt
    39601 atagaaggtc ttgaagtagg ttagggcttc tttgaccttc atttgctcat tgagataggt
    39661 cgtatcaggc aaataagcta caacggcctt ggttgctggg cttgggtcca tgtcgttgat
    39721 gaggacacgt ccttgatctg gttgtaagag gccattaatt agtttaatca gggttgtttt
    39781 tcctgagccg tttggcccaa gaaggccgac aatttttcca gctggaatgt caagagaaac
    39841 attttcaagg gctggtgttg ctccatatga tttggataca ttttcaaata ctagtaatga
    39901 cataggctta aactccttta atataatcac tgactacgcc tggtagttct tctttttcat
    39961 agccaaaatg gatcatggag gaaacgaagt gttccaattc ttcttctgat aattgtttgc
    40021 gtgactgagc gattagctcc ttatccttag tcacaaatcg tccagttgtt cgcttgctgt
    40081 agacaaatcc ttctcgttca aggtctgata aggctctttg gatggtattg ggattgacac
    40141 cagcctcgct agctagctcc ctcacggttg gaagttgttg attgggttcc agtgtatggg
    40201 aaacaatctg aagcttgatt ttctccataa tctgtaaata gatgggtttt ttgttgtcaa
    40261 atgtccagga catcttagtc tcctttctct tatccttttg tcttaactaa ataatacaac
    40321 aaaacaaaaa acttgtcaag caaaaagaag aattgttttg ggaatcgctt aaaaaatggt
    40381 ataatgaaaa gaaaacgata aggagggaaa ggatgcgttg tccaaaatgt ggggctacca
    40441 agtcaagtgt tatcgatagt cgccaagcag aagaagggaa caccattcgt agaagacgtg
    40501 agtgcgacga atgccaacac cgttttacaa cctacgaacg agtagaagaa agaaccttag
    40561 tggttgttaa aaaagatggt acacgggaac aattctccag agataaaatc tttaatggga
    40621 ttatccgctc agcccagaaa cgtcctgtgt caagtgatga aatcaacatg gtagtcaatc
    40681 gtatcgaaca gaaactccgt ggtcgaaatg aaaatgaaat tcaaagtgag gacattggtt
    40741 cactcgtcat ggaggagttg gctgaattgg acgagattac ctatgtacgt tttgctagtg
    40801 tctatcgtag ttttaaggat gtcagtgagt tagagagctt gctccaacaa atcacccagt
    40861 cctctaaaaa gaaaaaggaa agataaatga agccaattga ccgtttttct tatctaaaga
    40921 ataatcgggt gtcgcaagat acctcatctc tggtacagtg ctacctcccg attatcggtc
    40981 aggaggcact gagcctttat ctttatacaa tcagtttttg ggataatggt agaaaggaat
    41041 atcttttttc aagtatcctc aatcatctca actttgggat ggatagactg ataaaatcat
    41101 tgaaaatctt atctgctttt aatctcttga ccctctatca aaagggggat gtttatcagc
    41161 tagccctcca tgctcctcta tctagtcaag acttcttgga gcatcctgtt tatcgcagac
    41221 tcttagagaa aaagattggc gactctgctg tggaggattt gaaagttgaa agtgctgatg
    41281 gtgaagaaat acctgtctca ctcaatcaag tctttccaga attggcagaa ctaggcagtc
    41341 aagaagacct tggtctcaag aagaaagtgg ccaatgattt tgacttggaa cattttcgcc
    41401 agctgatggc tcgagatgga cttcgttttg cggatgagca gtccgatgtc ttaaacctct
    41461 ttgctattgc cgaggagaag aaatggactt ggtttgaaac ctatcaattg gccaagtcaa
    41521 cagctgtttc tcaggttatt tcaaccaaac gcatgcgtga aaaaattgct caaaaaccag
    41581 tttcctctga ctttaatcct aaggaagcaa ccattatcaa ggaagctaaa agtaagactg
    41641 ccctgcagtt cttagcagaa atcaagcaaa cacgcaaggg gaccattacc caaacagaaa
    41701 gagaactttt gcaacagatg gctggcttgg gcttgctgga cgaagtcatc aatatcattc
    41761 tcttgttgac ctttaataag gtggattcgg caaacatcaa tgagaaatat gccatgaagg
    41821 tggctaatga ctatgcctat caaaagatac attcagcaga agaggccgtt ttacgaattc
    41881 gtgagcgagg gcagaaaaca aaaacacaaa aacagaatca gactgcccca gcaaaaacca
    41941 atattcctaa atggagtaac ccagattata agaatgaaac cagcgaggaa actcgtctgg
    42001 aactagaacg taagaaacaa gaactattag ctcgattaga aaaaggagga gattagatgg
    42061 aaagtgtcgg agacgtactc aaacgtcaac ccagccgttt ttattatcaa gatttggtcc
    42121 agaaaatcat gaaggaccct gatgttgcgg cttttatcca gcaagaatcc ttgactccag
    42181 aggaattaaa tcgcagtatc tccaagttta atcagtacat caccgagcgt gacaagtttc
    42241 tccgtgggga tacggattat attgccaaag gctacaagcc gattttggtt aagaatcatg
    42301 gctatgcaga tgtttcatat gaagaaactc ctgagctaat cgcggctgaa aaagaagcgg
    42361 ctattaagaa tcgtctcaag ctaatcaatc taccagccag tctcaaaaaa gctagtttgg
    42421 ctcaagttga tttggatgat ttgggacgct tgccagtttt tgaaaaacta ttagcctttg
    42481 tggagcaata tccagctatt cgaaaaggtc tttacttata tggagacttt ggtgtgggta
    42541 aaagtttcat ggtggcggcc ttagctcatg atttatcaga aaaacgtggt gtttcatcaa
    42601 ctctcctcca ctatcctagc tttgtcattg atgtcaaaaa tgctatcagt gatggcaatg
    42661 ttaagacctt ggtggatgag attaagctgt ctgaggtcct gattttagat gatattggcg
    42721 ccgagcaatc aaccgcttgg gtgcgtgacg aaatcctgca ggtcattctc caatatcgga
    42781 tgcaggaaaa tttaccgacc tttttcacat ccaacttcaa ctttgaagat ttggagaagc
    42841 attttgcgaa agtgaaacat ggaaatgacg aaacctggga agccagacgg gtcatggaac
    42901 gcatccgtta tttggctgag gagactcgtt tagaaggagt aaaccgtcga tgacagaaac
    42961 cattaaattg atgaaggctc atacttcagt gcgcaggttt aaagagcaag aaattcccca
    43021 agtagactta aatgagattt tgacagcagc caagatggca tcatcttgga agaatttcca
    43081 atcctactct gtgattgtgg tacgaagtca agagaagaaa gatgccttgt atgaattggt
    43141 acctcaagaa gccattcgcc agtctgctgt tttccttctc tttgtcggag atttgaaccg
    43201 agcagaaaag ggagcccgac ttcataccga caccttccaa ccccaaggtg tggaaggtct
    43261 cttgattagt tcggtcgatg cagctcttgc tggacaaaac gccttgttgg cagctgaaag
    43321 cttgggctat ggtggtgtga ttatcggttt ggttcgatac aagtctgaag aagtggcaga
    43381 gctctttaac ctacctgact acacctattc tgtctttggg atggcactgg gtgtgccaaa
    43441 tcaacatcat gatatgaaac cgagactgcc actagagaat gttgtctttg aggaagaata
    43501 ccaagaacag tcaactgagg caatccaagc ttatgaccgt gttcaggctg actatgctgg
    43561 ggcgcgtgcg accacaagct ggagtcagcg cctagcagaa cagtttggtc aagctgaacc
    43621 aagctcaact agaaaaaatc ttgaacagaa gaaattattg tagaaagtga gaaattatgg
    43681 ccctaccaac tattgccatt gtaggacgtc ccaatgttgg gaaatcaacc ctatttaatc
    43741 ggatcgctgg tgagcgaatc tccattgtag aagatgtcga aggagtgaca cgtgaccgta
    43801 tttatgcaac gggtgagtgg ctcaatcgtt cttttagcat gattgataca ggaggaattg
    43861 atgatgtcga tgctcctttc atggaacaaa tcaagcacca ggcagaaatt gccatggaag
    43921 aagcagatgt tatcgtcttt gtcgtgtccg gtaaggaagg aattaccgat gcagacgaat
    43981 acgtagcccg taagctttat aagacccaca aaccagttat cctcgcagtc aacaaggtgg
    44041 acaaccctga gatgagaaat gatatctatg atttctatgc tctcggtttg ggtgaaccat
    44101 tgcctatctc atctgtccat ggaatcggta caggggatgt gctagatgcg atcgtagaaa
    44161 atcttccaaa tgaatatgag gaagaaaatc cagatgtcat taagtttagc ttgattggtc
    44221 gtcctaacgt tggaaaatca agcttgatca atgctatctt gggagaagac cgtgttattg
    44281 ctagtcctgt tgctggaaca actcgtgatg ccattgatac ccactttaca gatacagatg
    44341 gtcaagagtt taccatgatt gatacggctg gtatgcgtaa gtctggtaag gtttatgaaa
    44401 atactgagaa atactctgtt atgcgtgcca tgcgtgctat tgaccgttca gatgtggtct
    44461 tgatggtcat caatgcggaa gaaggcattc gtgagtacga caagcgtatc gcaggatttg
    44521 cccatgaagc tggtaaaggg atgattatcg tggtcaacaa gtgggatacg cttgaaaaag
    44581 ataaccacac tatgaaaaac tgggaagaag atatccgtga gcagttccaa tacctgcctt
    44641 acgcaccgat tatctttgta tcagctttaa ccaagcaacg tctccacaaa cttcctgaga
    44701 tgattaagca aatcagcgaa agtcaaaata cacgtattcc atcagctgtc ttgaacgatg
    44761 tcatcatgga tgccattgcc atcaacccaa caccgacaga caaaggaaaa cgtctcaaga
    44821 ttttctatgc gacccaagtg gcaaccaaac caccaacctt tgtcatcttt gtcaatgaag
    44881 aagaactcat gcacttttct tacctgcgtt tcttggaaaa tcaaatccgc aaggcctttg
    44941 tttttgaggg aacaccgatt catctcatcg caagaaaacg caaataaaaa agtagaatct
    45001 ggaatgacag ttccggattt ttttgatata ataaaataat agaaaacgct atcaaaagaa
    45061 ggagggtgat gtcggtgatg gaacatttgt ttaaattctt acttttagca ccgtactttt
    45121 attttgataa ctggattgag aaggccaaca gaaatagtaa gttttttcca attttttatt
    45181 atttttactg gttttacatc cccttctatt ctctttttag ccttgcttgg acagttgttt
    45241 cagttctgtt tttcaatacc gtcttgagaa atgtgacaga tatcaagtta tggggcattt
    45301 ggtttctttt tattctgcta gctattggta tgaattggtt aacttattcc tgtttcaaag
    45361 aaatgtttcg cttgagacag gaactaggga agtctaaggg tggaaggcat tgatttatat
    45421 cggtttctat ttgtaggagg tggcttatgg tacctctaaa atcatttatt acacgctatt
    45481 ccaaggttta tattggtaat aacatttaat agaacgaaac taaagaaaac aatttaaaag
    45541 aggaggtttg tgatggaata cttgtttaaa atgataatct tattaccctg tttttacttt
    45601 ttcagctgga ttgaaaaggc aaacagagat agtaagattt tcccaatttt ttactatttt
    45661 tactggattt acatcaccct ctatgctctt tttagccttg cttggacagt tttttcagtt
    45721 ctgtttttca atatcgtctt gagaaatttg acagatatca agttatgggg tatttggcta
    45781 ttattactac ttatcgcttt tgctagtgac tggttagact atatctgttt caaaaaaatg
    45841 cttgacttga gacgggaact agggaagtct aaaggcggaa ggcattgatt tatactcttc
    45901 gaaaatctct tcaaaccacg tcaacgtcgc cttggattat atatgtaact gacttcgtca
    45961 gtcttatcta caacctcaaa gcagtgcttt gagcaacttg cggctagttt cctagtttgc
    46021 tctttgattt tcattgagta ttatattact ttctatttgt aggaggtggc ttatgaagat
    46081 tcctctctta actttggcaa ggcataaatt tgtttatgtc ttgcttactt tgctttttct
    46141 tgctttggtt tatcgtgatg ttttgatgac ttatttcttt tttgatattc atgcgcccga
    46201 tctagctaaa ttcgatggac aagcaattaa aaatgactta ttaaaatcag cattagattt
    46261 tcgtattctc cagttcaatc taggttttta tcaatcattt attattccaa tcatcattgt
    46321 tttgctaggt tttcaatata ttgagctgaa aaataaagtt ttacgattga gtattggaag
    46381 agaagtgagc tatcaagggt taaaaagaaa gttgactttg caagttgcaa gtatcccttg
    46441 tttgatatat ttagtgactg tgctgataat tgcaattata acctatttct ttgggacttt
    46501 ttctcctctt gaatggaatt ctctattttc tgatgggagt ggtttacaaa gactcctaga
    46561 tggagagata aaaagctatt tgttctttac ttgtgtccta ctaatcggta ttttcatcaa
    46621 tgcaatctat tttttacaaa tagttgatta tgtggggaat gtgactcgtt cggcaatcac
    46681 ctatttgatg tttctttggc ttggttctat gctgctctat agtgccttgc cttactatat
    46741 ggttcctatg acgagtttga tgcaagctag ctatggggat gtaagtttga tgaaactctt
    46801 tactccttat atccttcatg ttgtccctta tatggtactt aaaaaatatg aagataatgt
    46861 ttaagaattt taacaatatt tggctaaaga gaaagatcgt tttactactt cgtatagttc
    46921 tgatgatgat tttgataaac tatctattgt caacagcggt tcaaaagcag gatgctgtta
    46981 tctttttcaa gagagaattg atttcaattt tttcctataa tgactattct gaagcgaatt
    47041 tagaaatccc caaactcttg ttaaaccttt cgcttttcat ggtaggatgg ctctctgtca
    47101 ttttacttga aagtgatttg gcagaccatt accatcactt gattcgctat caatcaagct
    47161 cctttttcga ttatacaagg aaacgattgg ttgtcatttc taaatttttt actcaagatt
    47221 tgtttgtctg gtttcttggt ttacttccgc taggaattca tttcaaaaca gtcgcacttt
    47281 tctttttact tgctcagtta atgatgttgt acttactact gtcttatctg atagcactga
    47341 ttagtgcggg cgctggtttt tctttttttc tctatttttt ggcatttgtg ggacaagaat
    47401 ggatgatgga tcatattgta acagtgtatt tagtactctt aagcttatta gttatgttga
    47461 ttgttagtcg cttggaagag aaatttaaga aaggataaac gatgagactt gaaattataa
    47521 atggacagaa aatttatggg aaaagaccta ttttaaatca gttgaatttg gtgtttcaat
    47581 caggaaaaat ttatggactt aaaggtgata atggatctgg caagacggtt cttttaaaga
    47641 tacttgctgg ttatattaag cttgacaaag gaaaagttct tcaagatggt aaagtttacg
    47701 gggtaaaaaa tcattatatt caggatgcag gaattttaat tgaaaaagtc gagtttttat
    47761 ctcatttatc cctgagagaa aatttggaac tgttaaggta tttttcatct aaagttacgg
    47821 aaaaaagaat tgcctattgg attcaatact atgatttaca ggaatttgaa gacgttgaat
    47881 accgtcattt atccttggga acaaagcaaa aaatggcctt gattcaagcc tttatttcct
    47941 ctccttctat actctttctc gatgaaccta tgaatgcttt ggatgagaag agtgtgaggt
    48001 taaccaaaca ggtcatttta tcttacctga aaaaagaaaa tggtctggtt atcctgacgt
    48061 cgcacatatc ggaagatatt tcagaccttt gtacagatgt attagttgtc gaaaatggac
    48121 atatacaata tgtaaaggat atacaatcct aggagatggc ttatggcaca tctaaaatca
    48181 tttattacac gctattccaa ggtttatatt ggtttagttc tgctgatctg gctgtctttc
    48241 ttctttatcc cttgggatag agcgattctg ggggtaagga ttgacatctt catcatgcag
    48301 aaaatcttgc tagcttttgg aattctgtcc attctcatgg ccttgctgtc caagaaagtc
    48361 agtctctttg tttttggact gatttgctgt ctttctcttt ggattaactt atttatcaca
    48421 tttgccattt tgccgatttt tggcaattaa acagtcataa aagtcggaga ggttagcttg
    48481 aaaactaacc tctttttcct tttcaaaatg gggattcttc cttgaaaata atcagtaatt
    48541 gtgctaaaat taaaggaaca ttctaaaata ttcggaattt aaagtaagga aaaacatggc
    48601 taatatttta aaaacaatta tcgaaaatga taaaggagaa atccgtcgtc tggaaaagat
    48661 ggctgacaag gttttcaaat acgaagacca aatggctact ttgactgacg accaactaaa
    48721 agcaaaaaca gttgaattta aggaacgtta tcaaaatgga gaatcactgg attcattgct
    48781 ttacgaagca tttgcggttg tccgtgaagg tgccaaacgt gtcctaggtc tcttccctta
    48841 taaggttcag gtcatggggg ggattgttct tcaccatggt gacgtgccag agatgcgtac
    48901 aggggaaggg aaaaccttga ctgcgaccat gccggtatac ctcaatgccc tttcaggtaa
    48961 aggggttcac gtagttacgg ttaatgaata cctgtcagaa cgtgacgcga ctgagatggg
    49021 tgaattgtac tcttggcttg gtttgtcagt agggattaac ttggctacca aatctccaat
    49081 ggagaaaaaa gaagcctatg agtgtgatat tacttactca actaactcag aaatcggatt
    49141 tgactacctt cgtgacaaca tggtcgttcg cgccgaaaac atggtacaac gtccgcttaa
    49201 ctatgccttg gtcgatgagg ttgactctat cttgattgac gaggctcgta cacctttgat
    49261 tgtatcaggt gccaatgcgg ttgaaaccag tcagttgtat cacatggcag accactatgt
    49321 aaaatctttg aacaaagatg actacatcat cgatgtgcag tctaagacta ttggtttgtc
    49381 tgattcaggg attgacaggg ctgaaagcta cttcaaactt gaaaacctct atgacatcga
    49441 aaacgtggct ttgactcact ttatcgataa cgcccttcgt gccaactaca tcatgcttct
    49501 cgatattgac tatgtggtga gcgaagagca agaaatcttg attgtcgacc aatttacagg
    49561 tcgtaccatg gaaggtcgtc gttattctga tggattgcac caagctattg aagccaaaga
    49621 aggtgtgcca atccaggatg aaaccaagac atctgcctca atcacgtacc aaaacctttt
    49681 ccgtatgtac aagaaattgt ctggtatgac gggtacaggt aagactgagg aagaagaatt
    49741 ccgtgaaatc tacaacattc gtgttattcc aatcccaaca aaccgtcctg ttcaacgtat
    49801 tgaccactca gaccttcttt atgcaagtat cgaatctaag tttaaagcgg ttgtcgaaga
    49861 cgttaaggct cgttaccaaa agggtcaacc tgtcttggtt ggtacagtgg cggttgaaac
    49921 tagtgactac atttctaaga aattggttgc agctggtgtt cctcacgaag tcttgaatgc
    49981 caaaaaccac tatagagaag cccaaatcat catgaatgct ggtcaacgtg gtgccgttac
    50041 catcgcaacc aacatggcgg gtcgtggtac cgacatcaag cttggtgaag gtgttcgtga
    50101 acttggagga ctttgtgtta ttggtacaga acgtcatgaa agtcgtcgta tcgataacca
    50161 gcttcgtgga cgttcaggtc gtcaaggaga tccaggtgag tcacaattct acctatctct
    50221 tgaagatgat ttgatgaaac gttttggttc tgaacgcttg aagggaatct ttgaacgttt
    50281 gaacatgtct gaagaggcga ttgagtctcg catgttgacg cgtcaggttg aagcagctca
    50341 gaaacgtgtc gaaggaaata actacgatac ccgtaaacaa gtccttcaat acgatgatgt
    50401 catgcgtgaa caacgtgaga ttatctatgc tcaacgttac gatgtcatca ctgcagatcg
    50461 tgacttggca cctgaaattc aggctatgat caaacgcacg attgaacgtg tcgttgatgg
    50521 tcatgcgcgt gccaaacaag atgaaaaact agaggcaatt ttgaactttg ctaagtacaa
    50581 cttgcttcct gaagattcta ttacgatgga agacttgtca ggcttgtctg ataaggccat
    50641 caaggaagag cttttccaac gtgccttgaa ggtttacgat agtcaggttt caaaactacg
    50701 cgatgaagaa gcagttaaag aattccaaaa agttttgatt ctacgagtgg tggataacaa
    50761 gtggacagat catatcgatg cccttgatca attgcgtaac gcggttggac ttcgtggcta
    50821 tgctcagaac aaccctgttg ttgagtatca ggcagaaggt ttccgtatgt ttaatgatat
    50881 gattggttcg attgagtttg atgtgacacg cttgatgatg aaagcacaaa ttcatgaaca
    50941 agaaagacca caggcagaac gtcatatcag tacaacagcg actcgcaata tcgctgctca
    51001 ccaagcaagt atgccagaag atttggattt gagccagatt ggacgcaatg aactttgccc
    51061 atgtggttct ggtaagaaat ttaaaaactg tcacggtaaa agacaataaa atgagatagt
    51121 ttagaggcgg atatcttgtg aaaagtaaat ttttactggg tatccgtttg ctttataagg
    51181 agatgagtta tggtatttac agcaaaaagc tctaaaataa atatagaaga agttcgtgcc
    51241 ttgtcaaaat tagaaggtca ggctttggag aggaaatcac agcgcgatca agagctagaa
    51301 gccattatac gtggagaaga tcagcgaatt ctcttggtaa tcgggccatg ctcatctgac
    51361 aacgaagaag ctgtccttga atacgctaag cgtttggcag tcctacaaga agaagtggca
    51421 gatcgtatct ttatggttat gcgtgtttat actgccaaac cccgtaccaa cggagatggc
    51481 tataagggct tgattcacca gcctaacgcg acagaagcgc ctagtcttat caatggaatc
    51541 aaagccgttc gccatcttca ctatcgtgtc atcacagaaa cagggatgac aactgctgat
    51601 gaaatgcttt atcctgaaaa ccttccgctt gtagatgatt tgatttctta catggcagtt
    51661 ggtgcccgtt cagttgaaga ccagcaacac cgctttgtgg caagtggggc aggattttct
    51721 actggtttta aaaatccaac ctctggaaat ctcaatgtca tgtttaatgg gatttatgct
    51781 gctcaaaaca aacaaagttt ccttttctta ggaaaagaag tagaaacaac tgggaacccg
    51841 ctttcacacg ctattcttcg tggtgctctt aatgagtatg gaaaaaatat tcccaactac
    51901 tattatgaca atttaattga taccattgcc caatatgaga aaatgggctt ggaaaatcct
    51961 tttatcatca ttgataccaa tcatgacaat tctggtaagc agtatattga acagatccga
    52021 attgtccgcc agaccttgat taaccgtgct tggaatgaaa aaattaagca gttcgttcgt
    52081 ggttttatga ttgagtctta tctggaagat ggtcgacaaa atgagccaga agtatttggc
    52141 aagtctatca cagacccttg cctgggttgg gataacacag aagctcttgt cagagaaatt
    52201 tacaaaacgt taggagaata agatggcatt tattgaaaaa ggtcaagaaa tcgatatgga
    52261 agtcatcaag gctgaaaccc aattgtctgc ggaagccttg agactcaagg aaagccgtga
    52321 cagggaattg gcagatatta tttcagggga agatgaccgt attctcttgg tgattggtcc
    52381 ttgctcttct gataatgaag aggcggtctt ggaatatgct cgccgtttat ccgccttgca
    52441 aaagaaggta gcggacaaga ttttcatggt catgcgcgtg tatactgcta agcctcgtac
    52501 caatggagac ggctataaag gattggttca ccagccagat acttctaagg ctccaagcct
    52561 gattaacggt ttgcaggctg tgcgccagtt gcattaccgc gtgattacag agactggttt
    52621 gacaacggca gatgagatgc tttatccgtc aaatctgatc ttggtggatg acttggtcag
    52681 ctaccatgcc gttggagctc gttctgtgga agaccaagag caccgctttg tggcttctgg
    52741 gattgatgca ccagtaggga tgaaaaatcc aacctcagga aatttgggtg ttatgtttaa
    52801 cgccatctat gctgctcaaa acaagcaaac cttcctttat catgggcagg aagttgagac
    52861 atcaggtaat cctttggccc atgttatcct ccgtggagca gtcaacgagt atggcaatta
    52921 tatgccgaat tactactatg aaaacctact ccaagccatt gaacgctatg aaaccatggg
    52981 acttgaaaat ccttttatcc tcattgacac caaccatgat aactcaggca agcaatatat
    53041 ggagcagatt cgaattgttc gccagacctt gcagaatcgt gattggaatg agaaaattaa
    53101 aaagacggtt cgaggattta tgattgaatc ttacctagca gatggtcgtc aaaaccaacc
    53161 agagatcttt ggttgctcta ttactgaccc ttgcctaggt tgggaaaata cagaggcctt
    53221 ggtagaagag atttatgtta ccttgacaaa ataagtgaaa aggatggagt tggggaatct
    53281 caactccttt tgatgagaat gatagttgga cacggaattg acatcgaaga attggcttcg
    53341 atagaaagcg cagttacacg acatgaagga tttgctaagc gtgtactgac cgctcaggaa
    53401 atggagcgct tcaccagtct caaaggacgc aggcaaatag aatatttagc tggtcgctgg
    53461 tcggctaagg aggccttttc caaggctatg ggaacgggca ttagcaagct cggttttcag
    53521 gatttggaag tattgaacaa tgaacgtggg gcgccttatt ttagtcaggc accattttca
    53581 ggaaagattt ggctgtctat cagccacacc gatcagtttg tgacagccag tgtcattttg
    53641 gaggaaaatc atgaaagcta gtccacatag accaaccaag gctctgattc atctgggagc
    53701 tattcgacaa aatattcagc aaatgggggc tcatatccct caaggaacgc tcaagttggc
    53761 tgtggttaag gccaatgctt atggtcatgg agctgttgcc gttgccaagg caattcaaga
    53821 tgatgttgat ggcttttgcg tttccaatat cgatgaagcc attgaactca gacaagctgg
    53881 actcagcaag ccaatcctca ttttaggagt ttctgaaatc gaagctgttg ctctagctaa
    53941 agaatatgac ttcaccttga cagtggctgg actggagtgg attcaagcac tcttagataa
    54001 ggaagtggac ctaactggat tgacagtcca cctcaagatt gattcaggga tgggacggat
    54061 tggttttaga gaggcaagtg aggttgagca ggctcaagat ttgctccaac aacacggtgt
    54121 tcgtgttgaa ggaatcttta cccactttgc tactgctgat gaggaatcag atgactattt
    54181 taatgcccag ttagaacggt ttaaaactat tttagctagt atgaaggaag ttccagagct
    54241 ggttcatgct agcaattctg caacgactct ttggcatgta gagactattt tcaatgcggt
    54301 tcgtatggga gatgccatgt atggtctcaa tccaagtgga gcggtcttgg ctttgcctta
    54361 tgatttgata ccggccttga ccttggagtc tgctctggtt catatcaaga cagttccagc
    54421 tggtgcttgc atgggctatg gagcaactta tcaaacggat agcgagcaag tcatcgcgac
    54481 cgtgccaatc gggtatgcag atggatggac aagagacatg caaaatttct ctgtcttggt
    54541 agatggccaa gcttgcccaa ttgtcggcag ggtttcgatg gaccaaatca ctattcgatt
    54601 gcctaagcct tacccactcg gaaccaaggt aaccttgatt ggctccaatg gggataagga
    54661 aatcactgca actcaggtag cgacctaccg cgtaaccatt aactatgagg tggtttgcct
    54721 cctcagcgac cgtattccga gagaatatta ttagaaaaga aaggagtgga gcatgaatct
    54781 acatcaaccc ttgcatgtct tgcctggtgt gggaccaaag tcagcagaaa aatacgccaa
    54841 actaggaatt gaaaacttgc aagatctctt gctctacttt cctttccgtt atgaagactt
    54901 caaaaccaag caggtgctgg aactagaaga cggtgagaag gcagttcttt ctggtcaggt
    54961 agtgactcct gctagtgtcc agtattatgg tttcaagcgc aatcgcctgc gttttagtct
    55021 caagcaggga gaggtcgttt ttgcggtgaa tttctttaac cagccctatc tggctgataa
    55081 aatagagttg ggagcaaccc ttgctgtctt tggaaaatgg gaccgcgcta aggctagtct
    55141 gactgggatg aaggttctgg ctcaggtaga agatgacctc cagcctgtct atcgtctggc
    55201 tcagggaatc agtcaggcca gtctggtcaa ggtcatcaag acggcttttg atcagggact
    55261 ggacctcttg atagaagaaa atctgcccca gtctttacta gacaaataca aactcatgtc
    55321 ccgttgtcag gcagtccgag ctatgcattt tccaaaggat ttggcagaat acaagcaggc
    55381 tcttcgccgt atcaagtttg aggaactctt ttatttccaa atgcagttgc agatgctcaa
    55441 gtctgaaaat agagttcagg gaagtggtct ggttctgaat tggtctcagg aaaaagtgac
    55501 agcagttaaa gcaagtcttc cttttgccct gacccaagct caggaaaaga gtttgcagga
    55561 aattttaact gatatgaagt ccgaccacta catgaatcgt ctcctacaag gagatgtggg
    55621 gagcggaaaa acggtagtcg ctggcttggc catgtttgcg gcagtgacag caggttatca
    55681 ggctgcccta atggtaccaa cagaaatcct cgcagagcaa cactttgaga gtttacagaa
    55741 cctttttccc aatttgaaac tggctctctt gacaggttcc ttgaaagctg cagaaaagag
    55801 agaggtcttg gagaccattg ccaagggtga ggctgatttg attataggaa ctcacgctct
    55861 gatacaagat ggggtggagt atgctcgtct tggtttgatt attatcgatg agcagcaccg
    55921 ttttggtgtg gggcaaaggc gtattttacg ggaaaaaggc gacaatccag atgtcctcat
    55981 gatgacggcg actcccattc cacggacgct tgccatcaca gcctttggag atatggatgt
    56041 ttccattatc gaccagatgc cagcaggtcg gaagcctatt gtgacgcgct ggatcaaaca
    56101 tgagcaacta cctcaggtct tgacttggtt agagggggaa attcaaaaag gttcccaagc
    56161 ctatgtcatc tctcctttga ttgaagaatc agaagctcta gatttgaaaa atgccattgc
    56221 cttatcagag gagttgacga ctcattttgc aggcaaggca gaggtggctc ttctacatgg
    56281 taggatgaag agtgacgaaa aagaccagat catgcaggat ttcaaggaga gaaagacgga
    56341 tattctggtt tcgacgacgg ttattgaggt tggggtcaat gttcccaatg cgactgtcat
    56401 gattatcatg gatgccgatc gcttcggtct cagtcaactt caccagctta gaggtcgtgt
    56461 cggtcggggg gacaagcagt cctacgctgt tctcgttgcc aatcccaaga cggattctgg
    56521 gaaagaccgc atgcgcatca tgacagaaac gaccaatgga tttgtccttg cggaggaaga
    56581 tttgaaaatg cgtggttctg gtgagatttt tggaaccaga cagtcaggac ttccagagtt
    56641 ccaagtggct gatattatcg aagattttcc gattttagaa gaagcaagaa aggttgctag
    56701 ctacattagt tctatagaaa cttggcaaga agatccagag tggcgcatga ttgcccttca
    56761 tctggaaaag aaagaacatc tggattaagc tttctctaag gaaaacttaa gctagttttt
    56821 agatttggct cttatactaa agtcatcaaa aagaaacgag gactctcata tgacagtaac
    56881 gattaaagta aattaccaaa ccactttcca aaagaaggaa gca
//
LOCUS       DAYYYC010000007        54920 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.007, whole genome shotgun sequence.
ACCESSION   DAYYYC010000007 DAYYYC010000000
VERSION     DAYYYC010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54920
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.007"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..3892
                     /locus_tag="ACHBV5_000403"
     CDS             <1..3892
                     /locus_tag="ACHBV5_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0098024 - virus tail, fiber [Evidence
                     IEA];
                     GO_process: GO:0019062 - virion attachment to host cell
                     [Evidence IEA];
                     GO_process: GO:0046718 - symbiont entry into host cell
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HFM9966268.1"
                     /translation="GVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELASRI
                     ASVQASGRNLFLNSLFKQDISKTGIWTTSTYTATIDSESKYLGYNALKIIGLNPSGRD
                     GGNPKVTYPVLGQFGKVIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTL
                     STEIKRYVVHIPKGWTNESKQTTNEWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPED
                     IEGQISTVESTFKQRVNSLEAGVNRLTEGLRTKADISALNVTAENIRQSVKSLETDTQ
                     NKLNQKLSQAEFEVRAGSIRQEILNATKDKADKTLVVSEAGKLREEFSKMKVGGRNLW
                     IKSKTVGAVIEKLPENHVTGQKECYRLENNSTLTFNLEPDFSSRLYQKVTFSAWIKYE
                     NVVQGRNFWNVFNCFKHYLFRKNSETGVQSGPDYATLGMYKGSADWKYITFTYDYSEK
                     TNFDQLKTSLRFNLEGATSGTAWVTGIKVEIGSVATDWSPAPEDGENELLVAKTEFKR
                     TADGLSTKMAAVESYVGQDGQRQEALQRYTREESTRQATAVRELVNRDFVGKATYQED
                     VKGINQRIEAVKTSANKDIASQIASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNR
                     LTSSEQGTTTQISNISNRINSNKQGTDNQISNLKTQVATNKDNAERQMGRISDQVSAN
                     KANADSQFANVTNQLARKVETTDFQRVKETSKLYERILGNTENGIADKVARMALTNQL
                     FQVEVGKYSVSGPNLIKNSDFKNATNEWGSTQNLGRLVKHSFYHNGQKDLMRLSNATK
                     NENFLYSHRFNLERNTDYVLNFRGFNNSALASYDVYILGRRAGESDGFTIVKKVVSSK
                     KLSTSRCEDVSVTFNSGEMDNAYIRFDNNGSSSGTADLYITEVDLYKGYKPRTWQPHP
                     EDAVADANKKLEATQTKMTQLAGSWVVENINSAGDIISGINLGANGHNRFVGKLTHIT
                     GETLIDRAVIKSAMVDKLKTGNFEAGSVTTTILDAEAVTAEKLKVDDALIRKLTANDA
                     FIDRLTSKRIFSTKVESVISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGM
                     GNGAGHGVRTAFWANWGNNWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANF
                     YGNTTFSRSPVFSNGIELGSKDVLGDGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSDR
                     RLKENITDTAVKALDKINRLRMVAFDFIENKKHEEIGLIAQEAETIVPRIVSRDPENP
                     DGYLHIDYTALVPYLIKAIQELNQKIEKMEKTIA"
     gene            3889..4006
                     /locus_tag="ACHBV5_000404"
                     /pseudo
     CDS             3889..4006
                     /locus_tag="ACHBV5_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063632.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
     gene            3987..4190
                     /locus_tag="ACHBV5_000405"
     CDS             3987..4190
                     /locus_tag="ACHBV5_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966269.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITNNILSIQLDEQREGNQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            4193..4543
                     /locus_tag="ACHBV5_000406"
     CDS             4193..4543
                     /locus_tag="ACHBV5_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966270.1"
                     /translation="MAETNQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTVKPKE"
     gene            4553..4852
                     /locus_tag="ACHBV5_000407"
     CDS             4553..4852
                     /locus_tag="ACHBV5_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966271.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHAVGDIQKEMVRMNDRMEEIEKGE"
     gene            4856..5188
                     /locus_tag="ACHBV5_000408"
     CDS             4856..5188
                     /locus_tag="ACHBV5_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140911 - pore-forming activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFM9966272.1"
                     /translation="MQQITEIITNGAISILVILAGIAVKAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            5192..6148
                     /locus_tag="ACHBV5_000409"
     CDS             5192..6148
                     /locus_tag="ACHBV5_000409"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFM9966273.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKQDIENGLRAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKNTWYYLDAKEG
                     AMVSNAFVQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(6400..7368)
                     /locus_tag="ACHBV5_000410"
     CDS             complement(6400..7368)
                     /locus_tag="ACHBV5_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFM9966274.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELESVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFVPSQLLGDGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            7504..8361
                     /gene="cdaA"
                     /locus_tag="ACHBV5_000411"
     CDS             7504..8361
                     /gene="cdaA"
                     /locus_tag="ACHBV5_000411"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFM9966275.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            8348..9127
                     /locus_tag="ACHBV5_000412"
     CDS             8348..9127
                     /locus_tag="ACHBV5_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFM9966276.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            9151..10503
                     /gene="glmM"
                     /locus_tag="ACHBV5_000413"
     CDS             9151..10503
                     /gene="glmM"
                     /locus_tag="ACHBV5_000413"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFM9966277.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            10577..10951
                     /locus_tag="ACHBV5_000414"
     CDS             10577..10951
                     /locus_tag="ACHBV5_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFM9966278.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            10953..11801
                     /locus_tag="ACHBV5_000415"
     CDS             10953..11801
                     /locus_tag="ACHBV5_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFM9966279.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASEFPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            12078..12845
                     /gene="dapB"
                     /locus_tag="ACHBV5_000416"
     CDS             12078..12845
                     /gene="dapB"
                     /locus_tag="ACHBV5_000416"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFM9966280.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            12842..14041
                     /locus_tag="ACHBV5_000417"
     CDS             12842..14041
                     /locus_tag="ACHBV5_000417"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFM9966281.1"
                     /translation="MRLMQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDLDLLLQAENLRQAQGKEVNPQVI
                     KETYQSLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            14038..15909
                     /locus_tag="ACHBV5_000418"
     CDS             14038..15909
                     /locus_tag="ACHBV5_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFM9966282.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLTTLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(16052..17236)
                     /gene="mntE"
                     /locus_tag="ACHBV5_000419"
     CDS             complement(16052..17236)
                     /gene="mntE"
                     /locus_tag="ACHBV5_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HFM9966283.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            17540..20236
                     /locus_tag="ACHBV5_000420"
     CDS             17540..20236
                     /locus_tag="ACHBV5_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFM9966284.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            20249..21040
                     /gene="yghU"
                     /locus_tag="ACHBV5_000421"
     CDS             20249..21040
                     /gene="yghU"
                     /locus_tag="ACHBV5_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HFM9966285.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTESVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            21156..21566
                     /locus_tag="ACHBV5_000422"
     CDS             21156..21566
                     /locus_tag="ACHBV5_000422"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFM9966286.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            21578..23173
                     /locus_tag="ACHBV5_000423"
     CDS             21578..23173
                     /locus_tag="ACHBV5_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966287.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            23240..23404
                     /locus_tag="ACHBV5_000424"
     CDS             23240..23404
                     /locus_tag="ACHBV5_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HFM9966288.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            23483..24211
                     /gene="yaaA"
                     /locus_tag="ACHBV5_000425"
     CDS             23483..24211
                     /gene="yaaA"
                     /locus_tag="ACHBV5_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HFM9966289.1"
                     /translation="MKILIPTAKEMNTDLPSIEAISLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTTQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(24488..25036)
                     /locus_tag="ACHBV5_000426"
     CDS             complement(24488..25036)
                     /locus_tag="ACHBV5_000426"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFM9966290.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            25357..25845
                     /locus_tag="ACHBV5_000427"
     CDS             25357..25845
                     /locus_tag="ACHBV5_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HFM9966291.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGISQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            25842..27029
                     /locus_tag="ACHBV5_000428"
     CDS             25842..27029
                     /locus_tag="ACHBV5_000428"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFM9966292.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            27022..27387
                     /locus_tag="ACHBV5_000429"
     CDS             27022..27387
                     /locus_tag="ACHBV5_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFM9966293.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            27403..28749
                     /gene="asnS"
                     /locus_tag="ACHBV5_000430"
     CDS             27403..28749
                     /gene="asnS"
                     /locus_tag="ACHBV5_000430"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFM9966294.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVKNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            28902..29192
                     /gene="rpsF"
                     /locus_tag="ACHBV5_000431"
     CDS             28902..29192
                     /gene="rpsF"
                     /locus_tag="ACHBV5_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFM9966295.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            29204..29674
                     /gene="ssbA"
                     /locus_tag="ACHBV5_000432"
     CDS             29204..29674
                     /gene="ssbA"
                     /locus_tag="ACHBV5_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HFM9966296.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            29706..29945
                     /gene="rpsR"
                     /locus_tag="ACHBV5_000433"
     CDS             29706..29945
                     /gene="rpsR"
                     /locus_tag="ACHBV5_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFM9966297.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            30240..31640
                     /locus_tag="ACHBV5_000434"
     CDS             30240..31640
                     /locus_tag="ACHBV5_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HFM9966298.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSIRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            31642..32001
                     /locus_tag="ACHBV5_000435"
     CDS             31642..32001
                     /locus_tag="ACHBV5_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HFM9966299.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEKKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            32055..32804
                     /locus_tag="ACHBV5_000436"
     CDS             32055..32804
                     /locus_tag="ACHBV5_000436"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFM9966300.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            32794..33093
                     /locus_tag="ACHBV5_000437"
     CDS             32794..33093
                     /locus_tag="ACHBV5_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFM9966301.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            33164..34099
                     /locus_tag="ACHBV5_000438"
     CDS             33164..34099
                     /locus_tag="ACHBV5_000438"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFM9966302.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRIITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            34185..34697
                     /locus_tag="ACHBV5_000439"
     CDS             34185..34697
                     /locus_tag="ACHBV5_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HFM9966303.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERDLHDSDF"
     gene            34681..35330
                     /locus_tag="ACHBV5_000440"
                     /pseudo
     CDS             34681..35330
                     /locus_tag="ACHBV5_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            35431..35625
                     /locus_tag="ACHBV5_000441"
     CDS             35431..35625
                     /locus_tag="ACHBV5_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFM9966304.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(35671..37116)
                     /locus_tag="ACHBV5_000442"
     CDS             complement(35671..37116)
                     /locus_tag="ACHBV5_000442"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFM9966305.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMEKSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGVDCYQIIQGKKESYPGDTAVAENYL"
     gene            37222..38844
                     /locus_tag="ACHBV5_000443"
     CDS             37222..38844
                     /locus_tag="ACHBV5_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFM9966306.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            39047..41005
                     /locus_tag="ACHBV5_000444"
     CDS             39047..41005
                     /locus_tag="ACHBV5_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM9966307.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            41177..42112
                     /locus_tag="ACHBV5_000445"
     CDS             41177..42112
                     /locus_tag="ACHBV5_000445"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966308.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTIYSRSKGSSVALENLLAVPKEKFE"
     gene            42137..42859
                     /locus_tag="ACHBV5_000446"
     CDS             42137..42859
                     /locus_tag="ACHBV5_000446"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966309.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLERFYKPLSGYILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEIL
                     IFDESTANLDADSEYAIISILYSALKEKTVVIIAHRLSTVKDVDCIFFLEGGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            43017..44111
                     /locus_tag="ACHBV5_000447"
     CDS             43017..44111
                     /locus_tag="ACHBV5_000447"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HFM9966310.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDTRDLIADLRQALEG"
     gene            44119..45285
                     /locus_tag="ACHBV5_000448"
     CDS             44119..45285
                     /locus_tag="ACHBV5_000448"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFM9966311.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVVTFAKR"
     gene            45378..48476
                     /locus_tag="ACHBV5_000449"
     CDS             45378..48476
                     /locus_tag="ACHBV5_000449"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFM9966312.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVVVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            48524..49141
                     /locus_tag="ACHBV5_000450"
     CDS             48524..49141
                     /locus_tag="ACHBV5_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HFM9966313.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVQPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            49152..50486
                     /gene="murC"
                     /locus_tag="ACHBV5_000451"
     CDS             49152..50486
                     /gene="murC"
                     /locus_tag="ACHBV5_000451"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFM9966314.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEVEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            50496..50960
                     /locus_tag="ACHBV5_000452"
     CDS             50496..50960
                     /locus_tag="ACHBV5_000452"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9966315.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            50957..51451
                     /locus_tag="ACHBV5_000453"
     CDS             50957..51451
                     /locus_tag="ACHBV5_000453"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9966316.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            51532..53187
                     /gene="mltG"
                     /locus_tag="ACHBV5_000454"
     CDS             51532..53187
                     /gene="mltG"
                     /locus_tag="ACHBV5_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFM9966317.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGSETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            53258..53740
                     /gene="greA"
                     /locus_tag="ACHBV5_000455"
     CDS             53258..53740
                     /gene="greA"
                     /locus_tag="ACHBV5_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFM9966318.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            54022..54420
                     /locus_tag="ACHBV5_000456"
     CDS             54022..54420
                     /locus_tag="ACHBV5_000456"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9966319.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAL
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT        16504 a        10280 c        12511 g        15625 t
ORIGIN      
        1 tggcgtgaag tcagcgcaag cgacgtatga ggagacgacg actcgtagac tgtcagaact
       61 gaccaacttg gccaatggta aagccagcaa gtcagaactc acgcagacag ctgaggagct
      121 agctagtcgg attgcgagtg tgcaggcatc cggtcgaaat ctattcttga actcactatt
      181 caagcaggat atttcaaaaa caggaatttg gacaacgagt acatatacgg ctactatcga
      241 tagcgaaagt aagtatcttg gatataacgc tcttaaaatt ataggtctga atccatctgg
      301 ccgtgatgga gggaatccca aggttactta tccagttctg ggtcaattcg ggaaagtaat
      361 tcccggaagt acgactaatc aagatgtaac cattagtttt tatgctaagg caaataaaaa
      421 tggaataatg ctaagatctc gattagggaa tatcggatat aaaactggaa atgtgacatt
      481 gtcgacagaa attaaacgat atgttgtcca tattccaaaa ggttggacaa acgaatccaa
      541 gcagaccaca aatgaatggt tgttcaattt caaccaggaa ggaaccgttt ggatttggat
      601 gccgaagttt gaaataagcg atgtagatac ttcttattca gaagctcctg aagatataga
      661 aggtcagatt tcaacagttg aatcgacctt taaacaacga gtcaactcgc tcgaagctgg
      721 tgtgaatcgt ctgactgaag gccttagaac caaagccgat atcagcgcac tcaacgtgac
      781 tgctgaaaat atccggcaat ctgtgaagag tcttgagaca gacacgcaga acaagctaaa
      841 tcagaagttg agtcaggctg aatttgaggt gcgagccggc tctatccgtc aggaaatcct
      901 gaacgcaacc aaggataagg cagataagac tttagttgta tctgaagctg ggaaattgcg
      961 tgaagaattt tcaaaaatga aggtgggagg ccggaatcta tggataaaat ccaagacggt
     1021 tggagctgta attgaaaaat tacctgaaaa ccatgtcaca ggtcaaaaag aatgttatag
     1081 gttagagaac aactctactt taacgttcaa ccttgaacca gatttcagct caaggttgta
     1141 tcaaaaagtt acttttagcg cttggatcaa gtacgaaaat gtagtccaag gtcgaaactt
     1201 ttggaatgta tttaattgct tcaaacatta tctttttaga aaaaatagtg agaccggagt
     1261 acagagtggt ccagattatg ctacgcttgg tatgtataaa ggttcggcag attggaaata
     1321 tattacattc acttatgact actctgaaaa aacaaatttt gatcaattga agacatcatt
     1381 gcgattcaat cttgaaggtg ctacaagcgg tacagcttgg gtaacaggaa tcaaggttga
     1441 aatcggtagt gtggcgacgg actggtcacc agcaccagaa gacggagaaa atgagctttt
     1501 agtcgctaaa accgagttca agaggacagc tgatggccta tctactaaga tggcagcagt
     1561 tgagagctat gttggtcaag acggtcagcg acaggaagcc ctacagcgct atactcgtga
     1621 ggaaagcacg agacaagcga cagcagtccg tgagctggtc aatcgtgatt tcgttggtaa
     1681 ggctacttat caagaagatg ttaagggtat caatcagagg attgaagctg ttaaaactag
     1741 tgcgaataaa gacatcgcta gtcaaatcgc tagctatcgt caatctgtag atggtaagtt
     1801 cacggatatt tcaagtcaga taactactta taagcaagat gtgggcggtc aaatcagtgg
     1861 tctatcaaat agacttacaa gcagtgagca aggaaccact actcagattt caaatatttc
     1921 aaatcggata aacagtaata agcaaggcac agataatcag atttcaaatt taaagactca
     1981 ggtcgctaca aacaaggata atgctgaacg acaaatgggt agaatatctg atcaggtttc
     2041 tgcaaacaaa gcgaatgctg atagtcaatt tgcgaatgtg accaatcaac tagcgcgaaa
     2101 agtagagact actgacttcc agcgtgttaa ggaaaccagt aaactttacg agcgaatttt
     2161 gggcaatact gaaaatggaa ttgcggataa ggttgctcgc atggctctga ctaatcaact
     2221 gtttcaggtt gaggttggga aatatagtgt aagcggccct aacctcatta agaatagtga
     2281 ttttaaaaat gctacgaatg aatggggctc aactcaaaat ttaggaagat tggttaagca
     2341 tagcttttat cacaacgggc agaaagacct tatgcgttta agtaatgcaa ctaaaaacga
     2401 aaactttttg tatagtcacc gttttaatct tgaacgaaat actgactatg tactgaattt
     2461 tagaggattt aacaacagtg ctctcgcaag ctatgatgtt tatattttgg gacgaagagc
     2521 aggcgagagc gatggattca caatcgttaa gaaagttgtt agcagcaaga aactatctac
     2581 ctctagatgc gaagatgtct cagtaacttt taattccgga gaaatggata atgcttacat
     2641 tcgttttgat aacaatggct catcatcagg aacagctgat ttgtatatta cagaagttga
     2701 cttgtacaaa ggttataaac ctagaacatg gcaaccacat ccagaagatg cagtcgcaga
     2761 tgcgaataag aagcttgaag caacgcaaac aaaaatgact caactagctg gctcatgggt
     2821 agttgaaaac atcaactcgg ctggagatat catctctgga atcaatcttg gcgccaatgg
     2881 acataaccgc ttcgttggga aattgaccca catcactgga gagaccctga ttgacagagc
     2941 agtcatcaag tctgccatgg ttgataagct gaaaacgggc aattttgaag ctggttcggt
     3001 cacgactacg atattagacg ctgaagcggt aactgctgag aagttgaaag ttgacgatgc
     3061 gcttattaga aaattaactg caaatgatgc ttttattgac cgactgacat ctaaacgtat
     3121 cttctctact aaggttgagt ccgtcatttc tagttcaacc ttcctagaag cctatcaagg
     3181 tcgaattggt ggattcacac ttggtcaatt tgaccagggt ggcggtcgct ggatttcagg
     3241 tgtcaatcag ttctctgttg gtatggggaa tggtgccggg catggagtcc ggacagcctt
     3301 ctgggcgaac tggggaaata attggaacta tgccggacct aaagcatgga acgtcaatac
     3361 tgatgggaaa atgtactgta ggaatgaagt cggtttttat gatcaagtgg atttttcgaa
     3421 ttcatcgaga gcaaacttct atgggaatac tactttttct cgttctcctg tgttttcaaa
     3481 tggtatcgaa cttggaagta aagatgtgct tggtgatggt tggaatccca aaggcggaag
     3541 gaatgcggtt gtttggtgga atcaggtcgg tagcggtagc gtgaagtatt ggatggaaca
     3601 aaaatcagac agacgcttaa aagagaacat cacagataca gctgtgaaag ccttggacaa
     3661 aatcaacaga ttaagaatgg ttgcatttga tttcatcgaa aataagaaac atgaggagat
     3721 tggtctaata gctcaagagg ctgaaaccat cgttccaaga attgtctcac gagatcctga
     3781 gaatccagat ggctatctgc atattgacta taccgcttta gttccttact taatcaaggc
     3841 tattcaagaa ttaaatcaaa aaatagaaaa aatggagaaa acaatagcat gaataacaac
     3901 atgttgacca atatcgcact ttaaagcaat tcaggagctt gctcttgaaa atagaaaacg
     3961 aacacacaga ttggagaact tagaaaatga acacagaaca gcttaaccaa gccttacaaa
     4021 tgacaattag tgaaatgtca acaacttcaa caaattcgat gattacaaat aatatcttga
     4081 gtattcagtt ggatgagcaa agggaaggga atcaaagact tcaagcacga gtggatgagc
     4141 tggaagctct gcttgatgaa caaactaaac cagcagacaa aggagaatag acatggcaga
     4201 aacaaatcaa aacacagata acttactaga ccttacaaaa atcacagaac catttgatct
     4261 tgcgagtgct ttgcgctaca tgaaagaaaa tggagagttc attcgttgca agaatgtaag
     4321 cgatgacttc tatatgtatc gtgatgttca aaaacgtcct gtgatcgtaa atggccgtcg
     4381 ccaactcaag gatgttgaaa ccgtttgggc gttcaaccag tggggtggta caatcgcaac
     4441 aatcaacgtc gccgttctgt tgaatcatga attctatatc atgaaatttg atgcagaggg
     4501 caatcctgac tggacggatc caacggtaaa acctaaagaa taggaggtgt gtatgccaat
     4561 tgaagaagct gaaaaaatcg ctcaaagtca ggtagcttgg gcgattttgt ttatcttgct
     4621 tttctttatt atcattcgat atcttatcaa gacttcggac aagcgagaga agaagattat
     4681 ggatttgcac gagcaatcaa aggccgactc taatagacga gaagagcgtt tgatgactca
     4741 cctagaaaag accactacag aattaaccac aatcactcac gcggtcggag acattcaaaa
     4801 agaaatggtt cgcatgaacg accgcatgga agaaatcgaa aaaggagaat aacaaatgca
     4861 acaaattact gaaatcatta ctaatggagc aatcagcatc cttgttattt tggctggtat
     4921 cgcagtcaag gcagtcaagg actacctggt tcaaaaaggt ggagaaaaga ccatcaaaat
     4981 cgttgaaatc ttggccaaaa atgcagtaaa tgccgttgag caagtagctg ctgaaactgg
     5041 ctacaaggga gatgaaaaac tggcacaggc tcgcgctaaa gtccgtgctg agcttacaaa
     5101 atacaatatt agcatgactg acaaagactt agacaccttc gtagagtcag cagtgaagca
     5161 gatgaatgac gcatggaaag gacgataggg aatggatatc gatagaaaca gactacgtac
     5221 aggcttgcca caggttgggg tgcagcctta tcgacaagta cacgcccatt caacaggcaa
     5281 ccgtaactca accgtacaga atgaagcgga ttatcactgg cggaaagacc cagaattagg
     5341 ttttttctcg cacgttgttg ggaacggtcg catcatgcag gtaggacctg tgaacaacgg
     5401 aagttgggat gttgggggcg gttggaatgc tgagagttac gcagcggttg aactgattga
     5461 aagccattca actaaagaag agttcatgac ggactaccgc ctctatatcg aattgctacg
     5521 caatctagcg gacgaagcag gcttgccgaa gactcttgat acagacgact tggcaggtat
     5581 caagacgcat gaatactgta ccaataacca accaaacaac cactcagacc atgtggatcc
     5641 atatccatat cttgctaaat ggggcattag ccgtgaacag tttaagcaag acatcgaaaa
     5701 cggcttgaga gctgcaacag gctggcagaa aaatggcact ggctactggt acgtacactc
     5761 agacggctct tatccaaaag ataagtttga gaaaatcaac ggtacctggt attatttcga
     5821 tggctcaggc tatatgcttt cagaccgctg gaagaagcac acagacggta attggtacta
     5881 ctttgaccaa tcaggcgaaa tggccacagg ctggaagaaa atcgctgaga agtggtacta
     5941 ttttgatgta gaaggtgcca tgaagacagg ctgggtcaag tacaagaaca cttggtacta
     6001 cttagacgct aaagaaggtg ctatggtatc aaacgccttc gtccagtccg cagacggaac
     6061 aggctggtac tacctcaaac cagacggaac actggcagat aagccagact tcacagtaga
     6121 gccagatggc ttgattacag ttaaataaat agaaaggaaa ctttctaaat tgttctttca
     6181 ccgcaggctc aggcttgcgg tttttttgtt ttaaaaaagg ggcaaaaaag gggcaaaagt
     6241 gtcgtaaatc tctgtaaaat gatgtaaaaa catttattta aaagctcaaa atatagctgt
     6301 tttaaaaggt attgtaagat atagtaaaac gatgtaaagg tatttttaaa tgcggatgaa
     6361 ttataaaacc acgaatccta tgtgactcgt ggttcttttt tataaactgg tagagtgttt
     6421 tggttgtact ttttgttcag ggtcaatgta gttgatagcg ttgttgacag cagttggagc
     6481 ttcccctaga cctgtcgcaa tcagatcaat ttttccgtca tagtagcagc agtcaccgat
     6541 agcatagata cctgcttggc tggattcttg tttgctgttg acgataatct tgtgacggtt
     6601 gaggtcgagc ccccagtttt taaggttacc gacagaagat ttgaaaccat agttgacaaa
     6661 gaggtggtct aggtcaatgg tttcagtttc atcagatttg acttttgtga tttcaagttt
     6721 atcaagcgtt tttccatctc caaggagttg gctagggacg aatggtgtct tgatggttac
     6781 agatgattct tgcaaggctt gaacactgtg ttccaaggca cggaaattat ctctgcggtg
     6841 aacaagggta gttggtgcga ttttttcaaa agccaaagtc caatccacag ccgagtctcc
     6901 cccgccaaga atcgtcactt tcttaccagc gtattgctga atgttagaaa cgtggtagtg
     6961 gatattttca tagccctcaa cactttcaag ttccagcgga cgtggtttga aggcaccgcc
     7021 acccatagcg atgataactg ttttagtcag gtgacttcct ttagaagttg tgatggcaaa
     7081 ttcttcttct tgtttgtcaa tctcaagaac cgtttcattg agatgaatag gggtatcaaa
     7141 tccatttagc tgttcaatca agcggttagt caactcttct ccagtcaggt ttgggaagcc
     7201 tggtacgtct aggatttcct tttcagggta gagaatagca ggttgtccac ctagctgggg
     7261 aagagagtcg atgatttgaa ccttggcttg gcgtaggtgg gcataaaagg ctgcaaaaag
     7321 cccgacagga ccaccaccca caatggtaat atcatagagt tgagacatag tttctccttt
     7381 gttttttcta gtcagtttat tttatcatat ttttgttcaa tgtaaaatgg actaggatag
     7441 ggaaaaaaat gccagaaaat ggtataatag gacgaaagtg ttttgatagg gaggatatca
     7501 gggatgaatt ttcaacaatt atccaatctg caatattgga ccagtttgtt tgcaagtcca
     7561 tggacgatag ctatcaatct gattgatatt ttgattgttg cttatatttt ataccatttt
     7621 acaaaagcta ttgcaggaac caagattatg attttggtac gtggagtttt ggtgtttatt
     7681 ttagctcaaa tccttgcaaa tatgattggt ttgactacga tttcttggtt aatcaatcaa
     7741 attattactt atggggttat tgcggcggtt gttatcttct ctccagagat tcggactggt
     7801 ttggaacgtt tgggaagagc gacagatttt ttttccaatg cccctattag tgctgaggaa
     7861 cagatgattc gtgcctttgt taagtctgtt gaatacatga gtcctcgtaa aatcggggcc
     7921 ttggttgcta ttcagcgtgt acgtaccttg caggagtata tttcgacagg aattcccttg
     7981 gatgctaaga tttctgcaga acttctcatt aacattttta ttcccaacac tcccctacat
     8041 gatggtgcgg tgattatcaa agaagaacgt atcgctgtga cgtctgccta tctgcccttg
     8101 acaaaaaaca cagggatttc caaggaattt gggaccagac accgggcggc tatcggttta
     8161 tcagaagtct cagatgcctt gacttttgtc gtatcagagg aaacgggagg aatttcgata
     8221 acctataatg gaaggtttaa gcacaaccta acacttgatg aatttgaaac agaattacgt
     8281 gaaatcttac ttccaaaaga ggaagtgggt cttagtttta aagaacgatt gctaggagga
     8341 tggaaacatg aaaaaaaata gtttatatat catatcctca ctcttttttg cttgtgtctt
     8401 atttgtctat gctacggcga cgaattttca aaacagtacc agtgctaggc aggtaaaaac
     8461 ggaaacctat actaatacag taacaaatgt ccctattgac atacgctata atagtgataa
     8521 gtattttatt agcggttttg cttcagaagt atcagtggtc ttgactggtg caaatcgcct
     8581 atcgctagct agtgaaatgc aagaaagtac acgtaaattc aaggttactg ctgacctaac
     8641 agatgccggt gttggaacga ttgaagttcc tttgagcatt gaagatttac ccaatgggct
     8701 gaccgctgtg gcgactccgc aaaaaattac agtcaagatt ggtaagaagg ctcagaagga
     8761 taaggtaaag attgtaccag agattgaccc tagtcaaatt gatagtcggg tacaaattga
     8821 aaatgtcatg gtgtcagata aagaagtgtc tattacgagt gaccaagaga cattggatag
     8881 aattgataag attatcgctg tcttgccaac tagcgaacgt ataacaggta attacagtgg
     8941 ttcagtacct ttgcaggcaa tcgaccgcaa tggtgttgtc ttaccggcag ttatcactcc
     9001 gtttgataca ataatgaagg tgactacaaa accagtagca ccaagttcaa gcacatcaaa
     9061 ttcaagtaca agcagttcat cggagacatc ttcgtcaacg aaagcaacta gttcaaaaac
     9121 gaattaaaaa tagaaaagga ttttataaca atgggtaaat attttgggac tgatggagtc
     9181 cgtggagaag ctaacctaga actaacacca gaattagcct ttaaactagg acgttttgga
     9241 ggctatgttc ttagtcaaca tgaaacggaa gcgccgaaag tctttgtagg acgtgacaca
     9301 cgtatttcag gggaaatgct ggaatcggcc ttggtggcag gtctcctttc agtagggatt
     9361 cacgtataca aacttggtgt ccttgcaaca ccagcagtag cttacttggt tgaaactgaa
     9421 ggagcaagtg ccggtgtcat gatttctgct agccacaacc cagcccttga taacggaatc
     9481 aagttctttg gcggtgatgg cttcaaacta gatgatgaaa aagaagcaga aattgaagcc
     9541 ttgctagatg ctgaggaaga cactcttcct cgtccaagtg cagaaggctt aggaatcttg
     9601 gtagattatc cagaaggctt gcgtaagtat gaaggatatc ttgtttcaac tggaactcct
     9661 cttgatggaa tgaaggttgc cttggataca gctaatggag cagcttctac cagtgcccgt
     9721 caaatctttg cagaccttgg tgcccaattg acggttatcg gggaaacacc agacggtctt
     9781 aacatcaacc ttaatgttgg ttcaacacat ccagaagccc ttcaagaagt ggtcaaagaa
     9841 agtgggtcag ctattggttt ggcctttgat ggagacagtg accgcttgat tgctgttgat
     9901 gagaatggtg acatcgtcga tggtgacaag attatgtaca tcatcggaaa atacctttct
     9961 gaaaaaggac aattggctca aaatacaatt gtgacaactg ttatgtctaa ccttggtttc
    10021 cacaaggcct tgaatcgcga aggtattaac aaggcagtta ctgcagttgg tgaccgctac
    10081 gttgttgaag aaatgagaaa atcaggctac aaccttggtg gtgaacagtc tggtcacgtt
    10141 atcttgatgg attacaatac cacaggtgat ggtcaattat cagcagttca attgactaaa
    10201 atcatgaagg aaactggtaa gagcttatca gagttggcgg cagaagtaac gatttatcca
    10261 caaaaattag ttaatatccg agtggaaaac gtcatgaagg aaaaggccat ggaagtgcca
    10321 gctatcaagg ccatcatcga gaagatggaa gaagaaatgg cggggaacgg ccgtatcctt
    10381 gttcgtccaa gtggaacaga gcccctcttg cgtgttatgg cagaagcgcc tacaacagaa
    10441 gaagtagact actatgttga taccatcaca gatgtagttc gtgctgaaat tgggattgac
    10501 taaatcctag aaaactagat gaaaataaaa aattatgata caatagctta taatattgta
    10561 gccgatggag aaagacatga atcttaaacg tgaacaagaa tttgttagtc agtatcattt
    10621 tgatgcgcgt aattttgaat gggaaaatga aaatggagct cctgaaacca aggtggatgt
    10681 gaatttccaa ttgctccaac atgaccaaga aaatcaagtg acttccttga ttgtcatctt
    10741 gagctttatg attgtatttg ataagtttgt cattagtgga acaatctcac aagtaaacca
    10801 tatcgatggc cgtattgtca atgaaccaag tgaattgaac caagaagagg tggaaacctt
    10861 ggctcgtcca tgtttgaaca tgctcaatcg tttgacttac gaagtgactg aaattgcatt
    10921 agacttacca ggaattaatt tggagttcta atatgaaatt agctgttttc acagattcct
    10981 ctgcttatct cagtgcagag accttgcaaa gagaagactt gtttgtcttg gatattcctg
    11041 tcaatattga tggtgaggaa tatgtcgaag gcatcaatct gtctgctgag gaattttacc
    11101 aaaaaatggc tcaggcttct gaatttccta agaccagtca accaagtatt gccaagttag
    11161 atgaaatctt aacttcgctc aaagaacaag gctatacaca tgccttgggg cttttcctat
    11221 cttctggaat ttcaggtttt taccaaaata tccagtatat ggtcgatgac tatgagggct
    11281 taaccattgc tttcccagac actttgatta caagtgctcc cctaggcatc atggttgaaa
    11341 gcgtctttaa ttggcgtgat cagggcgatg attttgccag cattcaggat aagctagcca
    11401 ttcaaatcag ccgtacgtca gcctttatca tggtagatga cttggatcat ttggtaaaag
    11461 gtggacgcct ttcaaatggg gctgccattt tgggcaattt gcttagcatt aagccaatcc
    11521 tttattttaa cgatcaaggt gtgattgaag tttacgaaaa agttcgtact gaaaagaagg
    11581 ccaccaagcg cttaattgaa attatcaagg aaacaacggc ttcaggtcaa taccgggtca
    11641 ttgtcattca tgggaatgct cctgaaaagg ctgaagaatt gcgtcagcac ttgcttgatt
    11701 ttggcttggg ttcggatgtt tcacttgcta catttggtag tgtcattgga acgcacctag
    11761 gagcaggaag tattgctctg ggttatattc cagtgattta gttggcgctt ctaggctagt
    11821 taagatgcct tgtatcttag aaattgaaca cggactacct gcctcttgaa aaaagatgcc
    11881 tgtcttgcct ttcgtggaaa gtcagtgcca ttccctattt ttcagaggca gctaaggtcc
    11941 tttgtatctt gataattgaa cacgcctgga accctgtgtg aaaaagatag ttcttccaag
    12001 aagtagacac ttcttgattg gaattcctat tttcactttg tgttcttacg gactttgtat
    12061 cttagacagg agtagagatg agtattcgag taattattgc cggttttaag ggaaagatgg
    12121 gccaggctgc ttgtcagatg gtattgactg atccagactt ggacttggtg gcagttttgg
    12181 atccttttga gtctgagtca gaatggcagg gtattcctgt tttcaaggat aaggctgatt
    12241 tagctggttt tgaagcggat gtctgggtag attttactac tccagctgtt gcctacgaaa
    12301 atacacgttt tgctcttgaa aatggctttg ctccagtagt tggaacgact ggtttcacga
    12361 gtgaagaaat tgcagagcta aaagaatttt ctcgtgccca agacttgggt ggcctgattg
    12421 cccctaactt tgccttgggt gctgtcttac tcatgcaatt tgcgacgcag gctgccaaat
    12481 atttcccaaa tgtggagatt attgagctcc atcatgacaa gaaaaaggat gctccgagtg
    12541 gaacagccat taaaacagct gagttgatgg cagaggttcg agagtccatt cagcaaggtg
    12601 cagcagatga ggaagagctg attgctggtg ctcgtggtgc tgactttgat ggtatgcgca
    12661 tccactcagt tcgtttgcca ggcttggtag ctcatcagga agtcatcttt ggcaatcagg
    12721 gagaagggtt gaccctccgt catgactcct atgatcgcat ctccttcatg acaggagtca
    12781 atttgggaat taaagaagtt gtcaagcgtc atgagcttgt ctatggatta gaacacttat
    12841 tatgagatta atgcaaatgc cttctgaatt tcagaaggct ttaccagtat tagaaaaaat
    12901 taaagaagca ggctttgagg cttattttgt tgggggctct gttcgagatg cccttctcca
    12961 tagccctatc cacgatgtgg atattgcgac gtcttcttat ccagaagaga ccaagcagat
    13021 ttttccgcga acagccgata tcggaatcga gcatggaacc gtcttggtct tagatgggga
    13081 tgaggagtat gaggtaacaa cctttcggac agaggatgtc tatgtggact atcgcagacc
    13141 cagtgcggtt tcctttgtgc gctcgctaga agaagacctc aaacgccgtg atttcacagt
    13201 caacgccttt gccttggatg agacaggaga aatcgttgac ttgttccatg gtttagaaga
    13261 tttggaaaag caagtcttgc gagcagttgg agtggctagt gagcgtttca acgaagatgc
    13321 tttacggatt atgcgtggtt tccgttttca ggctagtctt ggttttgcac ttgagccaga
    13381 aacatttaaa gctatgaaga ccttgacgcc gcttttggag aaaatttctg tagagcgtac
    13441 cttcgtcgag tttgataaac tcttgctggc tccattttgg agaaggggct tggcttccat
    13501 gattgagagt caagcttatg actatctccc tgatatggca tctagccagg acaagctcaa
    13561 cagactgttt gatttggaga ctgattttac ttttgaatcc tctgaacaag cctgggcggc
    13621 tttactatgg gctttggaga ttgaaaatgc gcagtcattt ttgaaatctt ggaagacctc
    13681 acgccagttt gccaagcaag ttcaggattt gctgattatt ttggctctgc gtgaaaatgg
    13741 agaattgagt aagcgtgatt gttatcgctt tgacttggat ttacttttac aggctgaaaa
    13801 tcttcgtcaa gctcaaggaa aagaagtcaa cccacaagtc attaaagaaa cctaccagag
    13861 cttgactatt catgataaga aagaaatcca aatcaacggc ggtattttga tcaaggaata
    13921 tggctatcag ccaggcccag acttgggaga gattttaaca gagattgagt ttgccattgt
    13981 cgatggagaa ttggagaata atcgtgaagc catccatgct tacctgaggg agaaaaaatg
    14041 agtgatttta tcgttgaaaa actaagtaaa tccgttggtg acaagaccgt ttttagggat
    14101 atttccttta ttatccatga cttagacaga attggtttaa tcggtgtcaa tgggactggc
    14161 aagaccaccc ttttggacgt cctttctggt gtttctggat ttgatgggga tgtcagtcct
    14221 ttttcagcta aaaatgatta ccagattggt tacttgactc aggatcctga ttttgatgat
    14281 agaaagacag ttttggatac ggttctatct agtgaactca aggaaatcca gctcattcgt
    14341 gagtatgaat tgattatgct cgactatagt gaggacaagc aggcgcgttt ggaacgtgtc
    14401 atggcagaga tggactctct ccaagcttgg gaaatcgaga gtcaggtcaa gaccgttctt
    14461 agcaaattgg gcattcaaga cttatctact cctgttgggg aattgtcagg tggtctgaga
    14521 agacgggtac agttggcaca agtcttactt ggcaaccacg accttttgct tttggatgag
    14581 ccgaccaacc atctggatat tgcgattatt gagtggctga ccctcttttt gaaaaattct
    14641 aagaagaccg tcctttttat cactcacgat cgttatttct tagacgcttt gtcaacacgg
    14701 attttcgagt tggagcgagc aggcttgacc gagtaccagg gaaattacca ggactatgtt
    14761 cgcctaaagg cggaacagga tgagcgcgac gcggctcttc ttcacaaaaa agaacaactc
    14821 tacaaacaag aattggcctg gatgcgcaga caaccgcagg cgcgtgcgac caagcagcag
    14881 gcccgtatca atcgattcca tgatctgaaa aaggaagttt caggcagtag tgctgagaca
    14941 gacttgacca tgaactttga aaccagtcgg attgggaaga aagtcatcga gtttcaggct
    15001 gtttcctttg cctatgaaaa caagcctatt ttgcaagatt ttaatctctt ggtgcaggcc
    15061 aaagaccgta tcggaatcgt tggggacaat ggtgttggaa aatcaaccct gctcaacttg
    15121 attgcaggaa gtcttgagcc aactaaagga caagttgtga ttggggaaac tgttcgcatc
    15181 gcctatttct ctcagcaaat tgagggtttg gatgaaagca agagagttat caattacctg
    15241 caggaagtgg cagaagaggt caagaccagt ggcggttcta cgacttcgat tgcagagttg
    15301 ctggagcagt tccttttccc acgttcgacg catggaacct tgattgagaa attgtcaggg
    15361 ggtgagaaaa aacgtcttta tctcctcaaa ctgcttttgg aaaaaccaaa tgttcttctt
    15421 ttagacgagc caaccaatga cctagatatt gcaactttga cagtcttaga gaatttcttg
    15481 caaggttttg caggtcccgt tttaacagtc agtcacgacc gctatttctt ggataaggta
    15541 gcgaccaaga ttctcgcttt tgaggatggc aagattcgtc ctttctttgg tcattacacc
    15601 gactatcttg atgaaaaagc ttttgaaaca gatatggcca atcaagtgca aaaggtcgaa
    15661 aaggaaaaag tggtcaaggt tcgagaagac aagaaacgca tgacctacca agaaaagcag
    15721 gagtgggcaa gtattgaagg tgatattgaa accttggaaa aacgtatcgc tgctattgaa
    15781 gaggaaatgc aggctaacgg ctctgacttt ggtaagctga ctactctcca aaaagaattg
    15841 gatgagaaaa atgaagcact ccttgaaaaa tacgaacgct atgagtatct cagtgaattt
    15901 gatagttaag actattcgaa aatcaaagtg caaactatgt cggcttcaca ttgccgactc
    15961 aagtacagcc tgtgaccggc ttcctaattt gcactttgat ttttattgag tataaaagaa
    16021 tagaaaaatc ccgtctcatg aaaggatttc tctattcttt tttggtttct tgatgaaaga
    16081 tattttgcca ggtttcgtgg cgacgccaga tactggtatg gatgatacca tctaactcat
    16141 agcagatgag tttggttttt tgactgatgg aagtaatttg aatgtccttt atagcagaat
    16201 ttaactcttt tttggtctta taagcctctt tatccatctg ctctccatct tggcgaatat
    16261 agacaaaatc atcagtcaag agttcttcta gttggtttcc ttggtcaatc aattgttcac
    16321 gcataagcaa ttttttatag acattgtcta aaatttcatc ctcagggata ggtgctggtt
    16381 cgatatggac atcggtatca aagacgccaa aacgctcctc cagcatagac tcgacctgat
    16441 ccgcgatttc atggctttca aaaacagaca agtcaggatt catctctagt gtaatatcca
    16501 ggtagatgtt gctaccgtag gtgcgacctc tttgcgattt gaccttgctg attttgggaa
    16561 tttccatgat agccttttgg tagtcctcga gcaggcggtc gtcaaagcca tctgaaagac
    16621 taaaggaaga ctcgatgaag atatcatagg cagtcttcaa gataaagaaa gtgatgatga
    16681 tagcaaccag tttatccaca atcggataat tgaaactact agctaggatg gcaatggcgg
    16741 ttccaagtga ggtaacagcg tcagaaagat tgtccttagc agctgccttc agcgccttgg
    16801 agttggattt cttactgagg cgagtattgt agagatagac cacaaacata atcgctgcag
    16861 aaatgattcc tagagttgca ccaagaggat caatgaccgt ttcttcccga ctgagaatct
    16921 tttgaatggt atctcttaga acatcgaaac cgacatagaa catgatgata gaagtgatca
    16981 agcttgccaa atcttcaatc ttccaatgac caaaacggtg gtcacggtct gcaggctggc
    17041 gcgccatccg aatcccgatt aagagggcca catttccaat gatgtccgat acgttattaa
    17101 aaccatcggc caccaaactg gatgaatgaa ggagatgacc agctgctaat ttagctgcag
    17161 acaagatcaa ataggtcgaa atactgataa tggctccacg ctcagctaac ttgagatttg
    17221 agatagattg cttcattcaa cttcctttct agtcacatag cattctacca ttatactggt
    17281 tttcaaggaa aaattcaaat aaggcagttt ttactctttg aaaactcccc aaaatttggt
    17341 ataatggtac tactcaaggg agtagctggc agaaacctgt gatagtgtcg tcattccgaa
    17401 ttttatgctg aaaagtatgc tttccggccc tatcttaaac agcgagactt gttatgatta
    17461 acaggtctct ttttgtttgt cgtgaaaaga tatgacagaa agagagtctg ttttgcacac
    17521 aatgtcaagg aggagacaca tgtcaaaaga acaaaaacgc caagcgtttt atactcagag
    17581 ccctgaagag gtcttgcagg ctgtggatgc gaccgagcaa ggtttgtcat caagtgaggc
    17641 ggaaaagcgc cttgccgaat ttgggcacaa tgaactcgaa gaaggcgaga aacgatcaat
    17701 cttggtcaaa ttcatcgagc aatttaagga tttgatgatt atcatcctag ttgcggcagc
    17761 aatcttgtca gtcgtgactt ctggtgggga agatatcgca gatgccatta tcatcctagc
    17821 tgtggttatc atcaacgctg cctttggtgt ttaccaagaa ggaaaagctg aagaagctat
    17881 tgaagccctc aaatccatgt ctagtccagt tgcccgcgtt cttcgtgatg gacacatggc
    17941 agagattgac tctaaagaat tggtaccagg cgatatcgtt gcccttgaag caggtgacgt
    18001 ggtaccagcg gacctacgtt tgatagaagc caactctctt aaaattgaag aagcagcctt
    18061 gacaggtgaa tctgtaccag tcgaaaaaga cttgtcagtc gagcttgcga cagatgctgg
    18121 tattggtgac cgtgtcaaca tggccttcca aaactcaaac gtaacctatg gtcgtgggat
    18181 gggtgttgtt gtcaatacag gtatgtacac tgaagttggt catattgctg gtatgcttca
    18241 agatgcggat gagactgata caccactcaa acaaaacttg aacaaccttt ctaaggtctt
    18301 gacctatgct atcttggtca ttgcccttgt tacttttgta gtgggtgtct tcattcaagg
    18361 gaaaaatcca cttggtgagt tgttgacttc tgttgccctt gccgttgcag ccattccaga
    18421 aggacttcct gctatcgtta ccatcgttct ttctcttggt actcaagttt tggccaaacg
    18481 acattccatc gttcgtaagt tgccagcagt tgaaacactt ggttcaactg aaatcatcgc
    18541 ttctgataag actggtacgc tgactatgaa caagatgaca gtcgaaaaag tcttctacga
    18601 tgcggttcta catgactcag ctgatgatat tgaactaggt cttgaaatgc cactacttcg
    18661 ttcagttgtc ttggccaatg atacgaaaat cgatgtggaa ggtaacttga ttggtgaccc
    18721 aaccgaaaca gcctttatcc aatatgcctt ggacaagggc tatgatgtca aaggtttctt
    18781 agagaaatat cctcgtgtag ctgaattgcc atttgactct gaccgtaagc tcatgtcaac
    18841 agttcaccca ttgccagatg gtcgtttcct tgtagcagtc aagggtgcgc cagaccaact
    18901 cttaaaacgt tgtcttcttc gtgataaggc tggggatatt gctccgattg atgagaaggt
    18961 tacaaatctc attcatacaa acaattctga aatggctcat caagccttgc gtgtccttgc
    19021 aggtgcttat aagattatcg atagtattcc agaaaatctc acttctgaag agcttgaaaa
    19081 tgatttaatt tttactggtt tgattgggat gattgaccct gaacgtcctg aagccgctga
    19141 ggctgttcgt gtggctaagg aagcgggaat ccgtccaatt atgattacag gtgaccacca
    19201 agacacagcg gaagccattg ccaaacgttt gggaatcatt gacgcaaacg atacagaagg
    19261 tcacgtttta actggtgctg aactcaatga actgtcagat gaagaatttg aaaaagtcgt
    19321 tggtcaatac tctgtttatg cccgtgtgtc tccagaacac aaggttcgta tcgtcaaggc
    19381 ttggcaaaaa caaggtaaag tcgttgccat gacaggtgac ggtgtcaatg acgcgccagc
    19441 tctgaaaaca gccgatatcg gtatcggtat gggaatcact ggtacagagg tttctaaggg
    19501 ggcttctgat atgattcttg cagatgataa ctttgcgact attatcgtcg cagtggaaga
    19561 aggacgtaag gtcttctcaa acattcaaaa gactattcag tacctacttt ctgctaatac
    19621 tgctgaagta ttaaccatct tcctatcaac cttgtttggt tgggatgtct tacagccggt
    19681 tcatcttttg tggatcaact tggtaacgga taccttccca gctatcgctc ttggtgttga
    19741 acctgcagaa cctggcgtca tgaatcataa accacgtgga cgcaaggcaa gcttcttctc
    19801 aggtggtgtt ttgagttcta tcatttatca aggtgtactc caagcagctc ttgttatgag
    19861 tgtttatggc cttgcgattg cttacccagt tcatgtgggt gacaatcatg ctattcatgc
    19921 agatgcccta acgatggcct ttgcaaccct tggtttgatt cagctcttcc atgcctacaa
    19981 tgtcaagtct gtctaccaat ccatcttgac agttggccca ttcaagtcta agacctttaa
    20041 ctggtccatc ttggtatcct ttatccttct catggcaaca atcgttgtag aaccgcttga
    20101 aggaatcttc cacgtaacca aactagactt gtcacaatgg ggaattgtta tggctggaag
    20161 cttctcaatg attatcatcg tcgaaatcgt taagtttatt caacgcaaac tcggttttga
    20221 caagaatgcg atttaaggga ggtttcggat gtcagcatat caattaccga ccgtatggca
    20281 ggatgaagct agtaatcaag gagcttttac ggggctaaac agaccaacag caggtgcccg
    20341 tttcgaacaa aacttgccaa aaggagaaca agcttttcag ctttattcac tgggaacacc
    20401 aaatggtgtg aaggttacta tcttattgga agaattacta gaagctggtt ttaaggaagc
    20461 ggcttacgac ttgtataaga ttgctatcat ggatggggat caattcggct cagactttgt
    20521 gaagctcaat ccaaattcca agattccagc cttattggac cagtcaggta ctgaaagcgt
    20581 aagagtcttt gagtctgctc atattcttct ttaccttgct gagaaatttg gagccttttt
    20641 accaagtaat cctgtggaaa aggtagaagt tttgaattgg ctattctggc aagcaggtgc
    20701 agcacctttt ctaggtgggg gatttggaca tttcttcaat tatgctcctg aaaaattgga
    20761 atatcctatt aaccgtttta cgatggaagt gaaacgccag ttggatttat tggataagga
    20821 attggctcag aaaccttata ttgcaggcaa tgactatacg attgcagata ttgctatctg
    20881 gtcttggtat ggacagttag ttcaaggaaa tctttaccaa ggttctgcaa aattcttgga
    20941 tgcctcaagt tatcaaaatc tagtaaaatg ggcagaaaaa attgccaatc gtccagctgt
    21001 taagcgtgga ttggaagtaa cttatacaga aattaaatag caaaaaagtc atcttcggat
    21061 ggctttttgc tacagttgag ggaaagggtt tgcagttatc ggcttttgtg ctataattgc
    21121 tataatatag taaaaagcaa gaggagtgtg aggaagtgga aaagaaaatt gtgaaggata
    21181 tcttattttt atctcaagtg tctcagccgg caagtcagga ggacctttat cttgccagag
    21241 atttgcagga tacactctta gcaaatcgtg atacctgtgt tggtctagct gccaatatga
    21301 ttggggtgca gaagcgcgtg attatcttta atcttggctt ggttcccgtg gtcatgttta
    21361 acccagtgct tctgtccttt gaaggatctt atgaggcaga agaaggctgt ttgtccttgg
    21421 taggtgtgag atcaactaag cgttatgaaa ccataaggct tgcctatcgt gacagcaagt
    21481 ggcaggaaca gaccattacc ttgacaggct tcccagctca gatttgccag catgagctgg
    21541 atcacttgga aggacgaatc atttaggagg aaagcaaatg aaacgaatag tctttgaact
    21601 tatttttatc gcaacgacct ggtatatctt tttaccgccc cttaacctga ccagctggga
    21661 atttctcttc ttcctctgtg ggcatttgtt agttgtggca atcttatttg gctttggcaa
    21721 ggggataaac cttgtcaaaa cggttcatgt gcgccacggt aaggcggaag ctgccttaaa
    21781 tcttgagggt ttcaaaatca atcggttagg gaaaattctg ttagcttcga ttggaggaat
    21841 tcttctcttg gcagctttgg tttccttggt aacttccagc atgtttcagg ctaaaaatta
    21901 tgccaatgta gtcacggtta cggaaaaaga ctttactgaa tttcctagga gtgacaccag
    21961 taaggttcct atcctagata gaagtactgc tgaaaaaatt ggagaccgct acttgggttc
    22021 cctaaccgat aaggtgtcgc aatacgtagc ggcagatacc tatacccaat tgacaattga
    22081 tgggaaacct tatcgggtca caccactaga atatgcagac cctatcaaat ggtttaacaa
    22141 tcaagccaag ggaatcggtg agtatatcaa ggtggacatg gtaactggaa atgcggattt
    22201 ggtggacttg aagacaccaa tcaagtattc agactcggag tattttaacc gtgatgtcaa
    22261 acgtcacctg cgcttgaagt acccgaccaa aatctttaaa actccatctt ttgaggtgga
    22321 cgatgagggc aatcctttct atgtagcaac ggtttaccaa aagcaatttg gacttgctgt
    22381 tcctcgtcct gcttcagtca ttatcttgga tgctacaaat ggagaaacca aggaatacag
    22441 cttatcagat gttccagaat gggtggacag gatctatcca gcagaggaaa ccattgagca
    22501 aatcaactac aacggcaagt acaaggacgg tttcttgaat gccatgattt ccaagaaaaa
    22561 cgtgacccag actaccaagg gctataatta cttgtctatc ggtaatgaca tctatctcta
    22621 cacaggtgtg acgtcggcta atgcggatga gagtaatctt ggtttcatcc ttgaaaatat
    22681 gcgaacagga gaaatcacta agtatagctt ggcttctgcg acagaagaat cagcccgtga
    22741 atcagcagaa ggtgctgttc aggagaaatc ctacaaagca accttcccaa tcctcatcaa
    22801 cctcaatgac aagcctctct acatcatggg cttgaaggac aatgctggct tggtcaaaga
    22861 gtacgccctg gtagacgcag tcgagtacca aaatgttatc gttgctacta cagtggaaga
    22921 gatgctcagc aagtatgcca ataaaaacga ccttgaaatt gacaatgcaa cgacagaaag
    22981 catcaatgga gtagtagcag acctcaaatc agctgttatc aagggagaca ctgtctactt
    23041 ctttaaagtt gatggcaaga tatacaaggt caaggcttca gtatccgatg accttcctta
    23101 ccttgaaaat ggtaaaacct tcgaaggtca agtaggaaaa gacaattatc tcaagacctt
    23161 taagctacgg taaaaatagg tttttttcag aaagtatatg ttataataag gtaaattaag
    23221 cctaatggag gacaaagaaa tgggttttta tttgatggtt gcttcaatgc tactcggact
    23281 gctcgctttg aagataggtt tttctcagtt caaggagaaa aaagataaat tcttatctat
    23341 cttaacaagt ttagctggca cagcccttgt tctcgtggct gtctggttag gatggcccaa
    23401 ataaatagaa aaacctcggt caaaccgagg tttttcaaat gaatttcttg gttgtggcta
    23461 aaaaatatgc tacactatca atatgaaaat tttaatccca acagcaaaag aaatgaacac
    23521 agacttgcca agtatcgagg caatttcttt aaaaccagaa agtcaggccg tgcttgatgc
    23581 cttggctctc tattctgcca gtcaattgga gagtttctac aaggtatcag ctgagaaagc
    23641 ggcggaagaa tttcaaaata tccaagcttt gaaaaggcaa actactcaac actatccagc
    23701 cttgaaactt tttgatgggc ttatgtaccg caacattaag agagataagc tgaccgaggc
    23761 ggaacaagat tatcttgaaa atcatgtctt cattacctcg gctttgtacg gtgttgttcc
    23821 agccttgtca cccatggctc ctcaccgttt ggattttttg atgaaattaa aagttgctgg
    23881 taagactttg aagagccatt ggaaggcagt ctatgatgaa gctctgaaga aggaagaagt
    23941 gattttctct ctcttgtcat cagagtttga gactgtattt tctaaggaaa tcagagcaaa
    24001 gatggtgacc ttcaaattca tggaggatag aggcggtcag ctgaagattc actcaactat
    24061 ctccaagaaa gcgcgcgggg cctttctaac agctttaata gaaaatcaag tacaaactgt
    24121 gggggaagca cgtcgcttga actttgctgg atttgtttac cgagaagatt tgtcacaacc
    24181 acagggattg gtttttgtaa aggaagtata gaaatcagat attttgtatt tggcaatatg
    24241 tatcatcagc tattttagtt tataaatgag aaaaaagcga acaagctagt cttctgagcg
    24301 tcagaaaagt agtcttgttc gcttttatta tgttatactc ttcgaaaatc tcttcaagcc
    24361 atgtcagtgt cgccttaccg tatatatgtt actgacttcg tcagttctat ctacaacctc
    24421 aaagcagtgc tttgagtagc ttgcggctag cttcctagtt tgctttttga tttttattga
    24481 gtgttagtta cttgatagct tcgaccaagt cttgagcttg tttttcaagt gagtttagga
    24541 ctgtttcttc aagaaccaat tttccgtctg cccaggcaga gtcattaaca cgtgcagcag
    24601 tgaaatcacc aacgccttgt gtacggataa atggcaagag gtctttgtag atagcgaaaa
    24661 gttgatcgtg ccctgcattg gctacagatg atactgtgac aaacttgtct tgaagggcag
    24721 aaacgccacg tgtatcagac aagtcaaggg cacgagatag ccagtcaagc aagtttttca
    24781 ctgtaccagg gatagagaag ttgtagactg gagagaaaat ccagatagca tccgcaacga
    24841 gaactgcttc acgagcagca gctacagctg gatgtgttgg aacttccaaa tcttggctga
    24901 agagaggaag ggctgaataa tcaaggtagc taacttccgc tttaccagca agtgctttct
    24961 cagcttcgag cgccatttgg tggttgaaag aaccttgacg tagtgatccg acgataaata
    25021 atactttttt agacatgatg tgtctccttt ttcttaaaat ttcgagaact ctctcgttgt
    25081 tataaaatat attacaacaa aacaaaagaa cttgcaagaa atttgctcag agtttatttg
    25141 aaaattgtaa aatttcggaa actctagtca tttgtgactg aaaaagtaag aactgtttca
    25201 ctttcaaaat cggttttgtt tgaagggaga aatagaattg gttgctcaaa gcacagcttt
    25261 gaggttgcag ataaagctga catggtttga agagattttc gaagagtatt cttatattca
    25321 cttgtaataa agcttaatag atggtaaaat agacgagtga aaaaaagaca aaacaaagca
    25381 aaaaataatc tactgtggca gtatggtcta gggatgacga ttttgtttgt ggttatcagt
    25441 gcttcctttc tgtatatggt ttctcttagc atgaaaccct atcaaacagc taaaagtgaa
    25501 ggagaaaaat tagctcagca gtatgcagga ttagagcagg ctgatcaggt tgatttatac
    25561 aatggcttgg aatcttatta cagcgttctt ggtcgtaata aacagcaaga agcgcttgct
    25621 gtcctgattg gtaaagatga ccataagatt tacgtttatc agctaaatca gggtatttca
    25681 caagaaaaag cagaaacggt ttctaaggaa aagggagctg gcgagattga caagataacc
    25741 tttggtcgtt atcaagacaa gccaatctgg gaagttaagt caggatctga tttttatcta
    25801 gtagattttg aaacaggagc attggtcaat aaggagggcc tatgaaacta tccaaccgtg
    25861 ttttagaaat ggaagaaagt gtgactttgg ctgctggagc ccgtgccaaa gcactgaagg
    25921 ctgagggtag agatattttg tctctaacct tgggtgagcc agatttcact actcccaaaa
    25981 atatccaaga tgccgccatt gcatcgattc gagatgggcg tgcttctttt tatacagtaa
    26041 cctcaggtct gccagagctt aaggcggtgg tcaatagcta ctttgagcgc ttttacggct
    26101 attctgtagc gtcaaatcaa gtgacagtcg ctgcgggagc caaatattct ctctatacct
    26161 tctttatggc tgtggtcaat ccaggtgatg aagtcatcat cccaacccca tactgggtta
    26221 gctatggaga tcaggtcaag atggcagaag gcgttcccgt ctttgtttct gctaaggaag
    26281 acaatcactt taaggtgacc gtagagcagt tagaagcagc tcgcactgac aagaccaagg
    26341 ttttggtgct gaattcgcca tctaatccca caggtatgat ttacacccgt gaggaactct
    26401 tggcaattgg aaactgggct gtagaaaatg atattctcat cctagcagat gatatctatg
    26461 gccgcttggt ttataatggt catgagttca caccgatttc tagcctatcg gaagcgattc
    26521 gcaagcaaac agtggtcatc aatggtgtgt ctaaaaccta tgccatgact ggttggcgga
    26581 ttggttatgc cgttggagaa gcagacatta tcgctgccat gtccaagatt gcaggtcaaa
    26641 caacttcgaa tccgtcagca gtagcccaat atgcagcagt tgaggctcta tcaggtgagc
    26701 aagatactgt agaaagcatg cgtcaggcct ttgaggaacg tcttaatacc atctatcccc
    26761 tccttgcaga ggtgccagga tttgaagtgg tcaaaccaca aggggccttc tatctcttcc
    26821 caaatgtcaa aaaggccatg gagatgaaag gctacacgga tgtgacagac tttacaactg
    26881 ctatcttaga agaagccgaa gtggccttgg taacaggagc tggatttgga gcaccagaaa
    26941 atgtccgcct cagctatgcg acagacctag acacgcttaa agaagcagtc gaacgcttga
    27001 aagcatttat gggtagtgag aatgattgat cattttgaga ttaaggtaaa ggatttacaa
    27061 atttcagaag gattttatag gagttttctc gctcctttgg actataaatt ggcttttaag
    27121 actagttctc taattagttt tctatccccg aacagccctc atcctggtgg tgatttttgg
    27181 ctgactcagg gaacacaaga tcctgttcat tttgcttttt tagcagaaaa taaggaagaa
    27241 gttcaggctt gttatgaggc tggcttagag gcaggtgggc gagacaatgg ggttcctggt
    27301 tatcgaagtg agcatccgat ttattatgct gcttttatga ttgacctgga tgggaacaat
    27361 atagaggtgg tttgccataa agaataaaaa agaaaaggaa aaataatgac aaaacgtgta
    27421 acgattattg atgtaaaaga ctatgttggt caggaagtga cgattggcgc ttgggttgcc
    27481 aacaaatcag gaaaagggaa aatcgctttc ttacaattgc gtgatggaac agccttcttt
    27541 caaggtgtgg cttttaaacc aaactttgtc gaaaaatttg gtgaagaagt gggacttgag
    27601 aagtttgatg ttatcaaacg cttgagccaa gaaacgtctg tttatgtgac aggtattgtc
    27661 aaagaggacg aacgttctaa atttggctat gagttggaca tcacagacat cgaagtgatc
    27721 ggtgaatctc aagactaccc aatcacacca aaagaacacg gaacagactt tttgatggat
    27781 aaccgtcact tgtggctacg ctctcgtaag caagtagctg tgttgcaaat ccgtaacgct
    27841 attatctatg caacttatga gttctttgac aagaacggtt ttatgaagtt tgacagccca
    27901 attctttcag gaaatgcggc agaagattct acagaactct ttgaaactga ctacttcgga
    27961 acgccagcct acttgagcca atcaggtcag ctttacctag aagcaggggc tatggctctt
    28021 ggtcgtgtct ttgactttgg tccagttttc cgtgctgaaa aatcaaaaac acgccgtcac
    28081 ttgactgagt tctggatgat ggatgctgag tactcatact tgacacatga tgagtcgctt
    28141 gacttgcaag aagcttatgt gaaagctctt ctacaaggtg ttcttgaccg cgcgcctcaa
    28201 gccttggaaa ccttggaacg tgatacagaa ctcttgaaac gctacattgc agagccattc
    28261 aaacgtatca cttacgatca agccattgac ctcttgcaag agcatgaaaa tgatgaagat
    28321 gctgactacg agcatcttga gcatggtgat gactttgggt caccacacga aacttggatt
    28381 tcaaaccact ttggtgtgcc aacatttgtc aagaactatc cagcagccat caaggccttc
    28441 tacatgaaac cagttcctgg aaatccagag cgcgtgcttt gtgcagactt gcttgctcca
    28501 gaaggctatg gagaaattat cggtgggtct atgcgtgagg aagattacga tgcccttgtc
    28561 gctaagatgg atgaacttgg catggatcgt acagaatatg aattctacct tgaccttcgt
    28621 aaatacggta cagttccaca cggaggattt ggtatcggta tcgaacgtat ggtaaccttc
    28681 gcagcaggaa caaaacatat ccgtgaagct attccattcc cacgtatgtt gcaccgtatc
    28741 aaaccataag aacaggaaaa cgcccatgtg gcgttttttc gaattctagt gtttttactt
    28801 gcgtaaaaaa attttttcta gtataatagt ttattgtgag cgaacctcac ttaccccttg
    28861 caaagtcttg gggtcattag accaaaagga ggaacatatc aatggctaaa tacgaaattc
    28921 tttatatcat tcgtccaaac attgaagaag aagctaaaaa cgctttggta gcacgttttg
    28981 actctatttt gactgacaac ggtgcaactg ttgttgaatc aaaaacttgg gaaaaacgtc
    29041 gtcttgcata cgaaatccaa gatttccgtg aaggacttta ccacatcgtt aacgttgaag
    29101 caaatgacga tgcagctctt aaagagtttg accgtctttc aaaaatcaac gctgacattc
    29161 ttcgtcacat gatcgtcaaa attgacgcgt aagaaggtaa actatgatta acaatgttgt
    29221 acttgtaggg cgtatgacac gtgacgctga gttgcgttat accccatcaa atgtagcagt
    29281 tgcgactttt actcttgcag taaaccgtac atttaagagt caaaatggtg aacgtgaggc
    29341 tgattttata aatgtcgtta tgtggcgcca acaggctgaa aatcttgcta actgggctaa
    29401 aaaaggctca cttatcgggg tgacaggtcg tatccagact cgtagttacg ataaccagca
    29461 aggacaacgt gtctacgtga cagaggtcgt ggctgagaat ttccaaatgt tggaaagccg
    29521 tagtgtgcgt gagggtcaca caggtggagc ttactctgca ccaactgcaa actattcagc
    29581 acctacaaat tcagtaccag acttttcacg taatgaaaat ccatttggag caacaaaccc
    29641 attggatatt tcagatgatg atttaccatt ctaatggaca actaaactta taaaggagaa
    29701 aaaacatggc tcaacaacgt cgtggcggat tcaaacgccg taaaaaagtt gattacatcg
    29761 cagcaaacaa aattgaatat gttgattaca aagatactga gcttcttagc cgtttcgttt
    29821 cagaacgtgg gaaaatcctt cctcgtcgtg taacaggaac ttcagctaaa aaccaacgta
    29881 aagtaacaac agctatcaaa cgcgctcgcg taatggcttt gatgcctttc gtaaacgaag
    29941 attaaagaaa agacccggtt gggtctcttt ttcatgagct tgaaaacaag aaagcgaatt
    30001 aagaccccaa tgggtctttt ttcacaaact ttgaaatgag agagcgagtt aggctcagtg
    30061 gctccctttt tacgagtttg aaaacaagag aacacattaa aagcacgatg gagctttttc
    30121 ataaatatgt cttttttctc atccaagaaa ttaaaataaa aatgataaac tttttgaaaa
    30181 taggggattt gcctacttta tgatataatg gaaagagtta gattgaaaga ggtagtgaga
    30241 tggacgcgaa attaagatac aaggcaaaga agatcaagat tgtctttttt gatattgatg
    30301 atacattgcg gaattcaaag acagggttta ttccaactac aattcccact gtttttaaac
    30361 agttgcgtga aaaaggaatt ttaacaggaa tcgcctctgg acgtggcatt tttggtgttg
    30421 ttccagagat tcgtgatctc aagcctgact tttttgtaac tttgaatggg gcttatatcg
    30481 aagataaaaa aggtcaggtc atttatcagc atcagattga aaagtcagat gttgaggagt
    30541 atatctcttg ggctaagcaa gaaggaattg agtatggctt ggttgggagt catgatgcca
    30601 agttgtcgat tcgcaccgat atgatgagtg aagctatcaa tccaatttat cccgacttag
    30661 atgtagatcc cgatttccat gaaaaagaag atatctatca gatgtggact tttgaagata
    30721 agggagatga cttgcacttg cctgacagtc tctcagacaa acttcgcatg gttcgttggc
    30781 atcaacattc gtctgatatt gtgccgattt caggctccaa agcgacgggg gtggaaaagg
    30841 ttgtggaaca ccttggcttg aaaccagaga aggtcatggt ttttggagat ggtctcaacg
    30901 acttggaact ctttgattat gctggaatca gcgttgccat gggaatttct catgataaaa
    30961 tcaaagaaaa agcagattat attacaaaaa cattagaaga agatggcatt tttgatgcct
    31021 tagaagtatt tggtatggta gaaaaagaat tgcattttcc acaagtagac attgaaacag
    31081 tagaaggtcc tcttgcgact attaagacca atcacggaga cttacgtatc aagcttttcc
    31141 ctgaacatgc tcctaaaaca gtggctaact ttgtatctct ttcaaaagat ggctactatg
    31201 atggtgtcat tttccaccgt attatcaagg actttatgat ccaaggtgga gacccaactg
    31261 gaactggtat gggtggcgag tcaatctacg gcgaatcttt tgaggatgaa ttctcagaag
    31321 agctttacaa tatccgtggt gctctttcca tggcaaatgc tggtccaaat accaacggca
    31381 gccagttctt tatcgtgcaa aaccaacacc taccttattc taagaaagaa attactcgtg
    31441 gtggttggcc agaaccgatt gcagaaatct atgccaatca aggtgggaca cctcacctag
    31501 accgccgtca cacggttttt ggtcagttag ctgatgaagc atcttacgct gtcttggatg
    31561 ccattgctgc tgttgagaca ggagctatgg acaagccagt tgaagatgtt gtaattgaaa
    31621 ctattgaaat cgaggactaa gatgaaaatc ggtgataagc taaaggggcg tattacaggg
    31681 attcagccct acggtgcctt tgttgagtta gagacgggtg atacggggct gattcacatt
    31741 tcagagattc ggacaggatt tattgaaaat attcatgaaa ccttgaaagt cgatgaagag
    31801 gttcaagttc aggtagtgga tttagatgaa tttacgggga aagccagtct ttctatccgc
    31861 actttggagg aaaaaaagta ccagtttcct agacggagac gcttttcaag cgaccgcttt
    31921 aactacggtt ttgctccctt tcgacgaatg ctaccaatct ggactggaga agccctgcac
    31981 catttaaaaa agaagaagta gtttagagtt ttatattttt tgtaatgtta atatgaattt
    32041 gctataatag gaccatggaa gaagaacaat tattaaaatc aggagagcgc attaaccagc
    32101 tcttttcgac agatatcaaa atcattcaaa atagagaggt ttttagctat tcggtggata
    32161 gtgttctctt atcacgattt ccacgttttc ctaagaaggg gttgattgtg gatttctgtg
    32221 ctgggaatgg agcagtgggg ctttttgcta gcactcgtac tcaagcacag atattgtctg
    32281 ttgagattca ggagcgtttg gcggatatgg ctgaacgctc tgtccgtttg aatggattag
    32341 aggagcaaat gcaggtcatc tgcgatgatt tgaaaaatat gcctgctcac attcagggga
    32401 gtaaggtgga tatgattttg tgtaatccac cctatttcaa ggtggatcct tattctaatc
    32461 tgaacgagag tgaacattat ctcttggctc gacacgaaat cacgactaat ttggaagaaa
    32521 tctgtcgtag tgcccagagt attctcaagt ctaatgggcg tttggccatg gttcatcgtc
    32581 ctgatcgact tctggatatt ttggatacgt taaaacgaca taatctagcc cctaagcgcc
    32641 tgcagtttgt ttatccaaaa agagaaaagg aagccaatat gcttttgatt gaggcgatca
    32701 aggatggctc aacaagtggc tttaaggtct tacctccttt gattgtccac aatgatgatg
    32761 gctcttatac gcccgaaatc gaagagattt attatggatc ataaggctta tatgtacgtt
    32821 ctggagtgtc gtgatggatc ctactatata ggctatacga ctgatatgag aagacgcctc
    32881 gctatccaca atagtgggaa gggagccaaa tatacacgag cacgcttgcc agtcaaactt
    32941 atctatgctc aaggttttgc cagtaaggaa gaagccatgt cggctgaagc tcttctcaag
    33001 cgtaagaaga ggccacagaa ggaagaattt ttatctgaaa atcaagatag aaatttactc
    33061 agttattttg aagaatcgtg gggagtcctt tgactcctct tacctttgtc aaaaagcgaa
    33121 aaaaatgcta caataaagaa aataaacaaa atgaggtatt atcatgtcca agattctagt
    33181 atttggtcac caaaatccag actcagatgc catcgggtca tctgtagctt ttgcctacct
    33241 tgcaaaagaa gcttacggtt tggatacgga agctgttgcc cttggaactc caaatgaaga
    33301 aacagccttt gtcttgaact attttggtgt ggaagcacca cgtattatca cttctgccaa
    33361 agcagagggg gcagagcaag ttatcttgac tgaccacaat gaattccaac aatctgtatc
    33421 agatatcgct gaagtagaag tttatggtgt tgtagaccac caccgtgtgg ctaactttga
    33481 aactgcaagc ccactttaca tgcgtttgga gccagttgga tcagcgtctt caatcgttta
    33541 ccgtatgttc aaagaacatg gtgtagctgt gcctaaagag attgcaggtt tgatgctttc
    33601 aggtttgatt tcagataccc ttcttttgaa atcaccaaca acacacccaa cagataaaat
    33661 cattgctcct gaattggctg aattggctgg tgtgaacttg gaagaatatg gtttagcaat
    33721 gttgaaagct ggtaccaact tggctagcaa atctgctgaa gaattgattg acatcgatgc
    33781 taagactttt gaactcaacg gaaataatgt ccgtgttgcc caagtgaaca cagttgacat
    33841 cgctgaagtt ttggaacgcc aagcagaaat tgaagctgca atgcaagctg ccaacgaatc
    33901 aaacggctac tctgactttg tcttgatgat tacagatatc gtcaactcaa actcagaaat
    33961 cttggctctt ggtgccaata tggacaaggt cgaagcggct ttcaacttca aacttgaaaa
    34021 caatcatgcc ttccttgctg gtgccgtttc acgtaagaaa caagtggtac ctcaattgac
    34081 tgaaagcttt aatgcgtaag attttgggtg tcagctcaaa atcggaaagt ctagtttgcc
    34141 ttatatcgaa aggagtttcg gctccttttt tctaggagtg aagtatgtta gaaaatggcg
    34201 atttgatttt tgtgagagat gggtcagaca tgggacaggc catccagact tccacaggta
    34261 actatagcca tgttgccatt tatttggatg ggatgattta tcatgctagt ggacaggctg
    34321 gtgttgtctg tcaagaaccg gcagacttct ttgagtccaa tcatttatac gacctctatg
    34381 tttacccaga aatggatatc cagtcggtga aggaaagagc ttgcaaacat cttggagcac
    34441 cctacaatgc ttctttctat ccagatgcag ctggtttcta ctgctcccag tatatagcag
    34501 aaatcctacc tatttttgaa actattccta tgaaatttgg agatggggag caggagatta
    34561 gtgatttttg gagggagtat tacatagaac taggtctgcc tgttcctctg aaccaagctg
    34621 gtaccaatcc tagtcagttg gcagcatcgc ctctgttaca atgtaaagaa agggatcttc
    34681 atgattcaga tttttaatcc atctcgtttg acgagacagc catttttgga gaattgatcc
    34741 gctatctgga ccagtatgag gatgtgattc tacgggaaat taaggctcaa tttccagatg
    34801 ttgcagttga taaactcatg gaagagtata taaaggcagg cttgattcta cgtgaaaata
    34861 agcgctatta cctcaatttt cctacgcttg aatcacttga tagtcttgaa ctggatcaag
    34921 agatttttgt cagagaagct agtccggtct atcaagcctt gttggagcag agttttgaga
    34981 cggaattgcg caatcaaatc aatgcagcta ttttagttga aaagacggac tttgcgcgca
    35041 ttaaaatgac cctgtccaat tatttttaca aggtcaaaca gcagtatcct ttgacagaaa
    35101 aacagcagga gctctatgac attttaggag atgttaatcc tgagtatgcc ctcaagtata
    35161 tgacggcttt tttgttgaaa tttctcaaaa aagaccagct tatgcagaaa tgccgtgata
    35221 tctttgtgga cagtttggtt gtcttaggct atattgtgca aaatgaagat agaaagtatg
    35281 agttggctat cgattttgat aaggagagat taactttcta cttagcgtga tttcttgttt
    35341 ctgagcacat tgtttgactt tccttagtat tcggtataaa ctatatgtaa ccggtaacac
    35401 atatcggaat aaactaaagg agacaatcat atgtcacttg aaaacaaatt ggaacaagca
    35461 acaggcgctg tcaaagaagg ttttggtaaa gttactggag acagcaagac agaacttgaa
    35521 ggagctgttg aaaaaacagt tgctaaggca aaagacgttg tagaagacgc aaaaggtgct
    35581 gtagaaggtg ccgttgaagg tttgaaaaac gtttttacta aataatagga aaaaatcaag
    35641 ggtttcattt tcccttgatt ttttctattc ttataaataa ttttctgcga cggctgtatc
    35701 tcctgggtag gattctttct tgccctggat gatttggtaa caatcgactc ccttacccgc
    35761 aataataact gcatctaatt cgtgatttgt gatagccatt gccgccttga tggcttcttg
    35821 gcgatccgca atcttttcaa caggatgatt gatgtagcta ctaatttcat ctgcaatggc
    35881 cattgggtct tcatagttag ggtcatcagc agtcagaaag acttgaatct cagggtgttg
    35941 attgaggagg aggccaaagt ccttacgacg actttctccc ttgtttcctg ttgatcccag
    36001 aaccagagca atctttccgg tttgatgagt ttcaaccaca ttgatgagtt ttttcagact
    36061 atccccattg tgggcatagt cgatgaagac cttggctcca tttttctgag tgaggacttc
    36121 catacgacca ggaacgcggg ttgcagcgat gccttttttg atgtcctcaa gacttgctcc
    36181 gagacggaga caagcaagtc cagcagcaac tgcattttct tggttgaagt tgccaatgag
    36241 ttgaatatca taatctccag cgagtttacc cgtagctgaa aagctaaagg ctttggaatt
    36301 ctcgatttgg ttatcaaatt ggctaccata gaaatcatgg tcttgatctt caacctgttc
    36361 tttcaagact gagaagtggt ccatgtcact gttaatgatg actgctcggc tcttttccat
    36421 caagagacgc ttgtggtaga aatagtcttc aaagctaggg tgttcaatcg ggccgatatg
    36481 gtctgggctg atatttagga aaactcccac atcaaaggtt agaccataga cacgtttgac
    36541 cagataggct tgactggaga cttccatgat gaggtgggta cggtcatttt gcacagcctg
    36601 attcatcatg tcaaagaggt caatactctc aggggttgtc aacgctgact taaagaaagt
    36661 ctcgccatca agagttgtgt tcatggtcga caacatagca ggtctatgcc cttgagataa
    36721 gatgttatag gcgaaatagg ctgctgttgt cttaccctta gtaccagtaa aggcaaggag
    36781 tttgagtttt tcctgtggat taccatagaa ctccatggca atcaaactca tggctttctt
    36841 tatatcgttc acaatgatga cagggatacc gacttcgtag tccttttcag ctacatacca
    36901 agctaatcct tgtgttatag cagaaagaag gtattctttt ttaaaggcag cgccttttgc
    36961 gaaaaaaaga gtgtcttctg ttacttttcg gctgtcgtag ctgatgctat caaaaataac
    37021 tttgctgtag ttgtagtggt aatgaccttg gtcaataatt tcgcgaaaaa ggccatcttt
    37081 ctttaaaata tctaatacgg tttcaatctt aatcatactt tctattgtaa accgaaagtc
    37141 gtaaatttac aagtaacaag gaaaagttta taatggaaga taaggagttt ttcctagcta
    37201 tcaaaattga atgaggaatc tatgtcgcac gaaaacaatc accagcaggc ccagatgtta
    37261 cgggggactg cttggctaac ggctagtaac tttatcagtc gcctactcgg ggctgtttac
    37321 attatccctt ggtacatctg gatgggggct tatgcagcta aggcaaatgg tctctttacc
    37381 atgggttaca atatctatgc ttggttcttg ttggtttcaa cagcggggat tccagttgcg
    37441 gtggccaagc aagttgccaa gtataatacc atgcgagaag aagagcatag ctttgccctg
    37501 attcggagtt tcttaggctt tatgacagga ctaggcctgg tttttgcttt agtcttgtat
    37561 gtctttgctc cttggctagc agacttgtct ggcgtgggca aagacttgat cccaatcatg
    37621 caaagcttgg cttggggagt cttgattttc ccgtctatga gtgttatccg aggatttttc
    37681 caagggatga ataacctcaa accctatgcc atgagccaaa ttgctgagca ggtcattcgt
    37741 gttatctgga tgctcctagc aacctttatc attatgaagc tcggttcagg agattatcta
    37801 gcagccgtta cccaatcaac ctttgctgcc tttgtcggta tggtagccag ttttgcagtc
    37861 ttgatttatt tccttgccca agaaggttca ctcaaaagag tctttgaaac aggagataag
    37921 attaacagta agcgtctctt ggttgatacc attaaggaag ccattccttt tatcctgaca
    37981 gggtctgcca tccagctctt ccagattttg gatcagctga cctttatcaa tagtatgagc
    38041 tggtttacca actacagcaa tgaggacttg gttgtcatgt tttcttattt ctcagccaat
    38101 cctaataaaa tcacgatgat tttgatttct gtaggggttt cgattgggag tgttggtttg
    38161 ccacttttga cggaaaacta tgtcaagggg gacttgaaag cagcttctcg tctcgttcag
    38221 gacagtctca ccctactctt tatgttcttg ctaccagcaa cggttggagt ggttatggta
    38281 ggagaacctc tatatacagt cttctatggt aagccagata gtttggctct gggcttattt
    38341 gtctttgcag ttttgcagtc tattatttta ggcttgtaca tggtcttgtc tccaatgctt
    38401 caggccatgt tccgcaaccg caaggccgtt ctctatttta tctatggttc tattgccaag
    38461 ctagtcttgc aactacctac catcgccctc ttccacagtt atggtccttt gatttcaaca
    38521 accattgctc tcatcattcc taacgtcttg atgtatcggg atatttgtaa agtaactggt
    38581 gtcaagcgca aggtgatttt gaagcgaact attttaatca gtttgctgac cctagtcatg
    38641 tttctgttaa taggaaccat ccagtggctg ttaggatttt tcttccaacc aagtggacgt
    38701 ttgtggagct tcttttatgt agctcttgtc ggtgccatgg ggggtggact ttatatggtt
    38761 atgagtctgc gtacctattt attagataag gtaataggaa aagcccaagc agatcgcctg
    38821 cgagcaaaat ttaagctttc gtaaggtagc atttataaat aaaaggaata agttgaacaa
    38881 tcttttagga gaacttgaaa cttattcctt ttttagcgta aaaatagcta aaattatctt
    38941 tcaaaaatag aaaatgaggt ttttttgatt ttttggaaaa aacaattgac taaacaaacc
    39001 aagagttgta taataaaaca aatatttaaa gcaggaggtt ccggaaatga aaaagtctaa
    39061 gagcaaatat ctaaccttgg caggtcttgt cctgggtaca ggagttttat tgagcgcgtg
    39121 tggaaattct agcacggcgt caaaaaccta caactatgtt tattcaagtg atccatctag
    39181 cttgaactat ctagcagaaa accgcgcagc aacatccgat attgttgcaa atttggtaga
    39241 cgggttatta gaaaatgacc aatatgggaa tattattcca tcattagcag aggattggac
    39301 tgtttctcag gacggtttga cctataccta caaacttcgt aaggatgcca agtggtttac
    39361 ttctgaggga gaagaatatg cgcctgtaac tgcccaggat tttgtgacag gtttgcaata
    39421 tgcagctgat aaaaaatcag aagccttgta tctagtgcag gactctgttg ctggtttgga
    39481 tgactatatc actggtaaaa caagcgactt ttcaactgtc ggtgtcaagg cacttgatga
    39541 ccaaacggtt caatatactt tggttaaacc agaactttac tggaattcaa aaacacttgc
    39601 aacgatactt tttcctgtta atgcagattt cctgaaatca aaaggggatg attttgggaa
    39661 ggcggatcca tctagtattt tgtacaatgg acctttcttg atgaaagcac ttgtctcaaa
    39721 atctgctatt gaatataaga aaaaccctaa ttactgggat gctaagaatg tctttgtaga
    39781 cgatgtgaaa ttgacctact atgatggtag cgaccaagaa tcactggaac gtaattttac
    39841 agctggtgct tatactacgg ctcgtctttt tcctaacagc tccagctatg aagggattaa
    39901 agaaaaatac aaaaacaata tcatctatag tatgcaaaat tcaacttcat atttctttaa
    39961 ttttaaccta gataggaagt cttacaatta tacttctaaa acaagtgaca ttgaaaagaa
    40021 atcgactcag gaagcagttc tcaataaaaa cttccgtcag gctatcaatt ttgcttttga
    40081 cagaacatct tatggggctc agtctgaagg gaaagaaggt gcaacaaaga ttttgcgtaa
    40141 cctagtggtt cctccaaact ttgtcagtat caagggaaaa gactttggtg aagttgtagc
    40201 ctctaagatg gtcaactatg gtaaggaatg gcaaggtatc aactttgcgg atggtcaaga
    40261 cccttactac aatcctgaga aagccaaggc taagtttgcg gaagctaaga aagaactcga
    40321 agcaaagggt gttcaattcc caatccactt ggataagact gtggaagtaa cagataaagt
    40381 aggcatacaa ggagttagtt ctatcaaaca atcaattgaa tctgttttag gttctgataa
    40441 tgtagtgatt gacattcagc aattaacatc agatgagttt gacagttcag gctactttgc
    40501 tcaaacagct gctcagaaag actatgattt atatcatggc ggttggggac ctgattatca
    40561 agacccgtca acctatctcg atatttttaa tactaatagt ggaggagttc tacaaaatct
    40621 tggactagag cctggagaag ccaatgacaa ggctaaggca gttggactgg atgtctatac
    40681 tcaaatgttg gaagaagcta ataaagagca agatccagcc aaacgttatg agaaatatgc
    40741 tgatattcaa gcttggttga ttgatagttc tttagttctt ccaagtgttt cgcgtggggg
    40801 aacaccatca ttgagaagaa ccgtaccatt tgctgctgcc tatggtttaa ccggtacaaa
    40861 aggggttgaa tcatataaat acctcaaagt acaagataag attgtcacaa cagacgaata
    40921 tgcaaaagcc agagaaaaat ggttgaaaga aaaagaagaa tccaataaaa aagcccaaga
    40981 agaattggca aaacatgtca aataaaatct aattgtagat aagtttgtgt aagaagtctt
    41041 tgtgcttaaa aacgcataat atcaggtata taaaatccta gatgttatgc gttttgttat
    41101 aggaagattt attagatttt atcctcaaat tgagttattc tcgactttat ccgttgaaat
    41161 attataagga gtatttatga aattaaaatt attaagagta gatactaagg tgattatggg
    41221 gagtttctta cttgttctgt ctagtctact tgctttgttg cttcccctta tcttaaaggg
    41281 tttaatagat gggagttcta ttgaaaatat aggttccaaa gtatttcaat cgtttttgat
    41341 ttttattggt caagccttgt tttcttctat tggttactat ctgtttagtc aatcgggtga
    41401 aaaaaagata gcaaaaatca ggaaaaaagt gatagagggg ttgatttatg cagagaaatc
    41461 cttctttgat aagagccaaa gtggggagtt gacttctgcc attgtcaatg acacgagtgt
    41521 cattcgtgag tttttaatta cgactttccc aaatattatt ctgagtttag ttatggtact
    41581 tggttccatt gtagtcttat ttagtcttga ttggaatctt tctctacttt tattcatcac
    41641 tcttccttgt atgatgttta ttatcttgcc cctttccaat atcagtgaaa agtatagtcg
    41701 tcgtttacag gaggaaatcg gatttttaac agggcaattg actgaaaaga ttcaagaaca
    41761 tgaattaatt aagactaacc aagcagagaa aagtgtacag gatgttttgg ataattgtat
    41821 tgaaagggta caaaacaatt cactgaaatc agatagggtt acttcttttg agaccccgtt
    41881 tgctctctta tttatctttg cgactatagt tgtgatgcta acctatgggg gttatcgggt
    41941 cagcgcagga tatatatctg tgggaacctt ggtttcgttt ttgatttacc tctttcaatt
    42001 acttaatcct attagtaata tagctaattt tgtaactatt tattctagga gcaagggatc
    42061 ttcagttgca ctggagaact tgcttgcagt tcctaaagaa aaatttgagt gaggaaaatc
    42121 ggtatcagga caagggttga attttaacca tgtctatttt ggttatgatg aaaatcgacc
    42181 tgtcttaaag gatattactt gttcaatttt caaggggcaa aaaattgctt ttgttggacc
    42241 atctggatca ggaaaatcaa cgattgtgcg tttgttagag cggttttata aaccgctttc
    42301 aggatatatt ctaatggagc aatcaagtat atatgatttt aacttaaaag aatggagaag
    42361 taaaatcgct tgggtttcac aaaataatgc agtcttatct ggcagtattc gtgacaatct
    42421 ttgtctcggt ttgaatcgct tagtaactga tgatgaattg atgaaagtgc tagacttagt
    42481 atcactaggt gatgagattc gctccatgaa agagggacta gatactgaag ttggtgaacg
    42541 cggacgattc ttgtcagggg ggcaaagcca aagacttcaa atagctagaa cctacttaaa
    42601 agatgctgaa attcttatat ttgatgaatc cactgctaat cttgatgcgg attctgagta
    42661 tgcgattatc agtatcctct attctgcatt aaaggagaag acggttgtga ttatagcgca
    42721 tcgtttgtca acggtaaaag atgtggattg tattttcttc ttagaggggg ggaaaatcac
    42781 tggctcagga actcataagg aactactgga aaatcatgag cgttatgctc gttttgtgca
    42841 ggagcaaatg atagagtgaa ggtgtctttt gagattcacc attttatagt ctattaaagg
    42901 gagcaggaaa aactcccttt ttatatagtt tgaaactata actagctctt gaaaagaaga
    42961 aaatgagttg atgaaaataa gtggtacaat agttactata gatttggagg tattgtatga
    43021 gcaaggaatt acacattaac acaattttgg ctcaggcggg tattaagtca gatgaagcga
    43081 caggtgcatt ggtgacaccg cttcattttt caacgaccta tcagcatcca gagtttggtc
    43141 gatctactgg gtttgactat acgcgcacta aaaatccaac tcgtagtaag gctgaggaag
    43201 tcttggcggc tattgagtca gcagactatg ccctagcgac tagctcaggg atgtcagcta
    43261 ttgtactggc ctttagcggc tttccagtag gaagtaaggt cttggcagtg cgtgatcttt
    43321 acggtggttc ttttcgctgg tttaaccaag tggagcagga aggtcgtttc cattttacct
    43381 atgccaatac agaagaagag ttgattgctg agttagaaaa ggatgtggat gttctctata
    43441 tcgaaacccc aaccaatccc ttgatgttgg aatttgatat cgaaaaacta gcaaaattgg
    43501 ctcatgctaa gggtgccaaa gtggtggtgg acaatacctt ctatagccct atctaccaac
    43561 gtccgattga agatggagca gatatcgttc tccattcagc aaccaagtat ctagcaggcc
    43621 acaatgatgt cttggctgga gtggttgtga ccaatagttt agaactatac gagaagcttt
    43681 tttacaatct caatacaaca ggggcagtct tgtctccatt tgacagctac cagttgcttc
    43741 gtggtctcaa gaccttgtct cttcgtatgg agcgctcaac agctaacgcc caagaagtgg
    43801 ttgccttttt gaaggattct ccagcagtta aggaagttct ctacactggt cgtggaggca
    43861 tgatttcctt taaagtagcc gatgaaacac gcattcctca tattttgaac agtctcaagg
    43921 tcttctcttt tgcggaaagt ttgggcggag tggaaagtct tattacttat ccaacgactc
    43981 aaactcatgc tgatattcca gcagaagtac gccattctta tggtttgaca gatgacctct
    44041 tgcgtttgtc tattgggatt gaggatacta gagatttgat tgcagatttg cgccaagcct
    44101 tagaaggata agacaaagat gggaaaatat gattttacaa gcctgcccaa ccgtttaggg
    44161 caccatacct ataaatggaa agaaacagaa acggatagtg aagttctacc agcttggata
    44221 gcggatatgg actttgtggt cttgcctgaa atccgccaag ccgtgcaaac ttacgcagac
    44281 caactggttt atggttatac ctatgccagt gaagacttaa ttaaggaagt tcaaaagtgg
    44341 gaagctacac aatacggtta caactttgac aaagaggctc ttgtctttat cgagggtgtg
    44401 gtaccagcca tctcaacagc tattcaaacc tttacaaaag aaggcgaggc ggttttaatt
    44461 aacacgcctg tctacccacc ctttgctcgc agtgtcaagt tgaataatcg tagattgatt
    44521 actaattcct tagtggaaaa ggatggtctg tttgagattg actttgacca acttgaaaag
    44581 gatttggtgg aagaggaggt taaactctat attctttgca atcctcacaa tcctggtgga
    44641 cgtgtttggg aaaaagaagt gttggagaag attggccaac tctgccaaaa acacggtgtt
    44701 ttgttagttt cggatgagat tcaccaagat ttgaccctct ttggtcacaa acaccagtct
    44761 ttcaatacca tcaatcctgc cttcaaaaat tttgctatcg tcttgagcag tgccactaaa
    44821 acatttaata ttgctggaac aaaaaattcc tatgcagtca ttgaaaatcc taagttgaga
    44881 ctggctttcc agaaacgcct gttggccaat aatcagcatg aaatttcagg cttgggttat
    44941 ttggcgacag aagctgccta tcgatacggt aaagattggc tagaggaact caagcaagtc
    45001 tttgaagacc acatcaatta tgtggtagat ctatttggaa aagagactaa aatcaaggtc
    45061 atgaaaccgc aaggtaccta cttgatttgg cttgactttt cagcctatga cctgactgat
    45121 gaaacattgc aagagttgtt gagaaatgaa gccaaggtta tcctcaaccg tggtttggat
    45181 tttggagagg aaggaagtct ccatgcccgc atcaatatag ctatgcccaa atctctgttg
    45241 caggaagtct gtcagcggat tgtggttact tttgccaaac gttaaaaatc cagtcttcta
    45301 ggagaaaagt cttcctagaa ggctattttc ataggcgaaa atatggtata ataaaaagat
    45361 aaggtaaagg tgaaaatatg gctaaattga ttccggggaa agttcgtatc gaaggtgttg
    45421 ccctttatga aactggtaag gttgatatca tcaaggaaaa gaacaatcgg ctctacgctc
    45481 gcgttgcaga agaagaactg cgctatagtt tagaggatga tttggttttt tgtgcctgtg
    45541 attcttttca aaagaggggc tactgtgtgc atttggcagc gctagagcat tttctgaaaa
    45601 atgatgagcg tggtcaggaa atcttgtgga gtctggaaga aggtcatgaa gaaaaagagg
    45661 ccgttgaaac caaggtgacc ttgggtggca agtttttgaa tcgaatttta tctccaaaat
    45721 cagaatgcgc ctatgagtta tcagctgtgg gtcaggtgga agcaggaacc aatcatatct
    45781 tgtggactct gagaatcggc caaatcaata gccaaaaata ctatgtcatt cgggatattc
    45841 cacttttttt aaggattgtc gagcagagaa agtcgtatat gattggcaag atttatgagg
    45901 agtctctttc ttgggaagcc tttgatgatg ccagccaaga acttttgact ttcttgcacg
    45961 gactaacgga ggaagggctg gttccagacc tctttttcca aaaccaaggt cggcacctct
    46021 ttttccctct gacctttttt gagcagggtg tgaatttact gatggccttg ccccattttc
    46081 aatttgacca tcaagtggat agctaccaaa ccctgctttt tcaggatatg catgctgatg
    46141 ccaatctatt tgcctttaca gtaacagaat actcggacta ttttgaaatg gaaatcagtg
    46201 agagtcctag ggtcaatgtc ttttatcaag gagcagtact tttccataaa ggtcaggttt
    46261 attttttaac agaccagcag atgcgtcttc tcaaggaaat taaagcgtta cctgtgggtc
    46321 aacaaggaaa gaaatacctg caatttgata gcagtgatcg agacaaattg gcctcctgtc
    46381 tgactctttt tatccagatg ggcaccgttt cagctccaga acgtctacaa atcaaaactt
    46441 ttgcgccctc tttttacttt gacagggaag aagataatcg gattcgttta gaaattcagt
    46501 ttgattatgg aaatagacag gtatctagcc gacaagagct agaagaatta cccttttcaa
    46561 gtgacgcgga cttagaagaa agaattttcc aagtctgttt ggctgcgggc tttgaagccg
    46621 attttcaatc ttggcgtcag gccttaaaag cggagtctgt ctatcatttt tttcatgata
    46681 tcattccagt ctttgaaaaa ctcgggcatg ttgacctatc agataaacta gaagagcttt
    46741 atagcctagc gagtcctcag gtgcagattg cctccaaggg aggtctcttg gaaatccagt
    46801 ttgattttca aaatattgcc caggaggaaa tcgaccaagc catgcaggcc ttggttgcca
    46861 atcaggattt ttatattgat tcgtctaatc aagtttactt tttcgatgaa gaaaccaaga
    46921 aaattcgcca aaatctccag gaactggggc aatttgaatt aaaagatgga accttgcagg
    46981 ctcggaaatc cttggcctac agtttagctc atctctttga agggcgagac cgtgtttctt
    47041 tttcacaaga attccagaat ctggcccagg atttgacgca tccagaggac tttcctttgc
    47101 aagcaactca ggtcaaggct gacttgcgag attatcagga aaagggaatt ggctggttgc
    47161 agatgctcca tcattatggt tttggtggga ttttggctga tgatatggga cttgggaaaa
    47221 cccttcagac cattgctttt ttgactagtc aagtgacaaa agaaagtcga gtcttgattc
    47281 tcgctccgtc aggtttgatt tacaactggg cagatgagtt tcagaaattt gccccacagt
    47341 tggatgtggt tgttgttcat ggtttgaaag caagtcgtga ggagattctt gccgagagcc
    47401 atcaaatcta tgtgactagc tatgccacct tccgtcagga cagtgagttt tatcagggga
    47461 tggcctttga cttccttttc ttagatgagg ctcaggtcat gaaaaatgcc cagaccaaga
    47521 ttgcccagac cttgagacaa tttgtggtgc cgtcggtctt tgccttgtca ggaactccga
    47581 ttgaaaacca tctgggtgag ttgtggtcta ttttccaaat cgtcatgccc ggacttttgc
    47641 caagcaagaa agaatttatg aaattgccag cagagcgagt ggctcagttt atcaagcctt
    47701 tcgtgatgcg acgcaagaaa gaagaagttc tgactgaatt gccagacttg attgaggtgg
    47761 tttataaaaa tgaactggaa gaccagcaaa aggctattta ccttgcccag ttacaacaga
    47821 tgcgagacca tctggctcaa gtgtcagaac aggaatttca gcgaagtcgt gtggaaattt
    47881 tatctggttt gatgcgcttg cgtcaaatat gtgacactcc tgccctgttt atggaagatt
    47941 atcagggagc cagcggcaaa ctagatagtc tccgagacct actggtacag gtggcagacg
    48001 gcggacaccg tgtcttgatt ttctctcagt tcaagggaat gttggaaaaa attgaacaag
    48061 aactgccaga cttgggcctg acttccttta aaattacggg ttcaacccca gccaaggaaa
    48121 gacaagacat gaccaaggcc tttaatcaag gagaaagaga tgcctttctg atttccctca
    48181 aggctggtgg ggtcggtctg aacctgacag gtgcagatac agtgatcttg gttgaccttt
    48241 ggtggaatcc tgcggtggaa gcgcaagcca ttggccgtgc ccatcggatg ggtcaggaag
    48301 aaacggttga ggtctatcgc ttggtgacca agggaaccat tgaagaaaaa attcaggaac
    48361 tccaagaaca aaagaaacat ctggtgtcac aagtattgga cggcacagag tcacgtggta
    48421 gtctgaccct agcagaaatt agagaaattt tgggaatttc tgaagccagc acttgaaaaa
    48481 tcaagacaat acgctataat gaagtgttga aaggaaatag aaaatgaaac aagaacgatt
    48541 tccattggtg tcagatgacg aggtcatgtt gactgaaatg ccagtcatga atctctatga
    48601 tgagtctgat ctgatcagta atatcaaggg tgagtatcga gataaaaatt atttagaatg
    48661 ggctcctatt gctgaagaaa aaccagtaca accgattgaa aagcaagtag ggaaacctaa
    48721 aaaagctcct ttaggggtta aaaaagaagg aaagagctat gcggaggtgg cgcgtgaaga
    48781 agcgcgtgca gacttgaaaa agaaacgctc tgctaactat ctaactcagg atttcagcct
    48841 tgcgagacgt cattctcagc ccagtctagt tagacagggc aatcaaccga caactccttt
    48901 ccaaaaggaa aatcctggtg aatttgtcaa atatagccaa aaattgaccc agtctcatta
    48961 tatcttggcg gaagaagttc attctatccc taccaagaat gaagaagtgt cagcacctgc
    49021 tccaaagaaa aacaattatg attttctaaa gaagagccaa atctacaata aaaaaagtaa
    49081 acaaacagaa caagaacgtc gggttgccca agagttgaat ctgaccagaa tgacagaata
    49141 ggggagaaaa catgtcaaag acatatcatt ttatcggaat taagggatca gggatgagtg
    49201 ccttggcctt gatgttgcac cagatggggc acaaggttca gggatcagat gttgaaaagt
    49261 actactttac ccaacgcggt cttgagcagg caggaattac cattcttcct tttgatgaaa
    49321 agaatctaga cggtgatatg gaaattatcg ctggaaatgc ctttcgtcca gataacaacg
    49381 tcgaaattgc ctatgcggac caaaatggta tcagctacaa acgttaccat gagtttctag
    49441 gtagctttat gcgtgacttt gttagcatgg gagtagcagg agcacatgga aaaacttcaa
    49501 cgacaggtat gttgtctcat gtcttgtctc acattacaga taccagcttc ttgattggag
    49561 atgggacagg tcgtggttcg gccaatgcca aatattttgt ctttgaatct gacgaatatg
    49621 agcgtcactt catgccttac cacccagaat actctattat caccaacatt gactttgacc
    49681 atccagatta tttcacaagt ctcgaggatg tttttaatgc ctttaacgac tatgccaaac
    49741 aaatcaccaa gggtcttttt gtctatggtg aagatgctga attgcgtaag attacgtctg
    49801 atgcaccaat ttattattat ggttttgaag ttgaaggcaa tgactttgta gctagtgatc
    49861 ttcttcgttc aataactggt tcaaccttca ccgttcattt ccgtggacaa aacttggggc
    49921 aattccacat tccaaccttt ggtcgtcaca atatcatgaa tgcgacagcc gttattggtc
    49981 ttctttacac agcaggattt gatttgaact tggtgcgtga gcacttgaaa acatttgctg
    50041 gtgttaaacg tcgtttcact gagaaaattg tcaatgatac agtgattatc gatgactttg
    50101 cccaccatcc aacagaaatt attgcgacct tggatgcggc tcgtcagaaa tacccaagca
    50161 aggaaattgt agcagtcttt caaccgcata cctttacaag aaccattgcc ttgttggacg
    50221 actttgccca tgctttaaac caagcagatg ctgtttatct agcgcaaatt tatggctcgg
    50281 ctcgtgaagt agatcatggt gacgttaagg tagaagatct agccaacaaa atcaacaaaa
    50341 aacaccaagt gattactgtt gaaaatgttt ctccgctcct agaccatgac aatgctgttt
    50401 acgtctttat gggagcagga gacatccaaa cctatgaata ctcatttgag cgtctcttgt
    50461 ctaacttgac aagcaatgtt caataggatg ttcccatgga aattccaatt aagatcattc
    50521 aggcaagcaa gtctgatttg cctgagatag gggcacttca gacctcgtct tttccagctg
    50581 aaaagcagca actttcccat attttagaag aaagtatccg taagtgtgcg gatacctttc
    50641 ttctagctag ggatgaaaat caacttttag gctatatttt atcaagtccc cagtcagaca
    50701 atccgcaata tctaaaagta cattctttag tcatcgagtc tgaccatcag agacagggct
    50761 tgggaacact tcttcttgca gccttgaaag aggtggcagt tgagctggat tacaaaggga
    50821 ttcgtttgga gagtcctgat gagctgcttt cctattttga aatgaacggt tttgttgatg
    50881 aagaagcaac tttgctctat gcaactagcc agggctatag tatgatttgg tttaatccct
    50941 tttatctgga ggaacaatga aaatcagaca agcaagatta gaagatttgg atcggattgt
    51001 tgaacttgaa tttgaaaatt tttcggtcga agaagccatt cctccttctg tctttgaagc
    51061 acatttgaga gaaattcaga cctcttttct ggttgctgaa aaagaaggaa gaatcatggg
    51121 ttatatcgaa ggaccagttg gcctgcaccg ccatctgcaa gaccagtctt ttacagaaga
    51181 aataaaagac tatagtcatg agcctggtgg ttatatctct gtgacctgtc tgtctattgc
    51241 caaggaggca cagggactcg gactgggtca gaaattgctg acagccttga aagaagttgc
    51301 tcttgaagat gagagagatg gcattaatct aacctgtcat gactatctca tcgcctatta
    51361 tgaaaaacat ggatttgtca acgaaggcca gtcccagtca acctttgcag gggaaacatg
    51421 gtatgatatg gtctgggaaa tgaaaaaata agttaggaaa agtatcatag attgcttttt
    51481 ttggactttt aagatataat attatggatt atcaacaagg aggaaaaact tttgagtgaa
    51541 aagtcaagag aagaagagaa attaagcttt aaagagcaga ttctgagaga tttagaaaaa
    51601 gtaaaaggct atgatgaagt tctgaaagaa gatgaggcag tagttcgcac tcctgcaaat
    51661 gaaccttcag ctgaagaact catggctgat tccttgtcaa cggtagagga gattatgaga
    51721 aaagctccta ccgtgcctac tcacccaagt caaggtgtac cagcttctcc agcagatgag
    51781 attcaaagag aaactcctgg tgttccaagt catccaagtc aagatgtacc ttcttctcca
    51841 gcggaagaaa gtggatcaag accaggtcca ggtcctgtta gacctaagaa acttgaaaga
    51901 gaatacaatg aaaccccaac aagggtagct gtttcctata cgacggcaga gaaaaaagca
    51961 gaacaagcag gttcagaaac acctacgcct gctacagaaa cagtggatat catcagcgat
    52021 acatcacgtc gtagccgtag agaaggagca aaacccgtta agcctaagaa agagaagaag
    52081 tcacatgtga aagcttttgt gatttcattc cttgtattcc ttgccttgct ctcagcaggt
    52141 ggttactttg gttaccagta cgtgctagat tctttgttac ctatcgatgc taattctaag
    52201 aaatatgtga cggttggaat tccagaaggt tcaaacgttc aagaaatcgg tacgacgctt
    52261 gaaaaagctg gtttggtaaa gcatggtctg atttttagtt tttatgccaa gtataaaaat
    52321 tataccgact tgaaagcagg ttactacaat ttgcaaaaga gtatgagtac agaagactta
    52381 ctcaaagagt tgcaaaaagg tggaacagat gaaccgcaag aacctgtact tgcgactttg
    52441 acaattccag aaggttatac cttggatcag attgctcaag ctgtgggtca attgcaaggt
    52501 gacttcaaag agtctttgac agcggaggct ttcttggcta aagttcaaga tgagacgttt
    52561 atcagtcaag cagtagcgaa atatcctact ttactggaaa gtttgcctgt aaaagacagc
    52621 ggtgcgcgtt atcgtttgga aggatacctt ttcccagcta catactctat caaggaaagc
    52681 acaactattg agagcttgat tgatgagatg ttagctgcta tggataagaa cctatctcct
    52741 tactatagta ctatcaaatc taaaaatttg actgtcaatg agttgttgac cattgcttcc
    52801 ttggtcgaaa aagaaggtgc caagacagaa gatcgtaagc tcattgcagg tgtattctac
    52861 aatcgtttga atcgtgatat gccacttcaa agtaatattg caatcttgta tgcccaagga
    52921 aaactggggc aaaatatcag tctagctgag gatgttgcga ttgataccaa cattgattca
    52981 ccttataatg tttataaaaa tgtaggtctc atgcctggtc cagtcgatag tccaagtctg
    53041 gatgcgattg agtcaagcat caatcaaact aagagcgata acctctactt tgtagcagat
    53101 gtcacagaag gcaaggtcta ctatgctaac aatcaagaag accacgaccg caatgtcgct
    53161 gaacatgtca acagcaaatt aaactaaaca aactaaaatt atgtgatact tcacataatt
    53221 ttctttagaa aatattatca gaagaaagtt gagaaaaatg gcagaaaaaa catatcctat
    53281 gacccttgag gaaaaggaaa aacttgaaaa agaattagaa gaattgaaat tggttcgtcg
    53341 accagaagtg gtagaacgca ttaagattgc ccgttcatac ggtgaccttt cagaaaacag
    53401 tgagtacgaa gcagctaagg atgaacaagc ctttgtcgaa ggacaaatct ctagcttaga
    53461 aacaaaaatc cgctatgctg aaatcgtcaa tagcgacgca gttgcccagg acgaagtagc
    53521 gattggtaaa acagtcacca tccaagaaat tggtgaggac gaagaagaag tttatattat
    53581 cgtaggttca gctggtgcgg atgcctttgc aggtaaggtt tcaaatgaaa gcccaattgg
    53641 gcaggccttg attggcaaga aaacaggtga tacagcaacc attgaaacgc ctgttggtag
    53701 ctatgatgta aaaatcttga aggttgaaaa aacagcctaa aaacagaaaa aggagtgggg
    53761 aggcgatgtg cttcactcac tcctttttcc attttgctac tcttcgaaaa tctcttcaaa
    53821 ccacgtcagc gtcgccttgc cgtatgtatg gttactgact tcgtcagttt cctagtttgc
    53881 tctttgattt tcattgagta ttagatgtat aatgcattga agttaaaata gtacactttg
    53941 atttctaaga cattgttaga aattagatta aattccttaa tcgatttgcg catgttttat
    54001 ttcatttcat tataccttag attggaaaat aaggaatcac ataaatcgca agaaataggg
    54061 aatctgattc gtgtttataa ccgttcaaaa agagaagagg ctgaaagtga gccacttaat
    54121 ctttatgtcg aagatgaaaa gggcaatctc cttgcgggtt tgatagcaga gacttttgga
    54181 aattggctag aaatcgagta tttgtttgta aaagaggaac tgcgagggca aggaatcggt
    54241 tcaaaactat tgcaacaggc agaaagtgaa gctaagaatc gaaattgttg ttttgccttt
    54301 gtcaatactt accagttcca ggcactggac ttttatcaga aacatggcta caaggaagtt
    54361 ttttctttgc aagactatct ctacattagg caaagatatt attaccaaaa gaatctgtaa
    54421 ggcgagtatg gaggtggact gatgtatatg agtaactatc gataaatacc agttataacc
    54481 tagaaattgt gtctttctag acgatattga ggacaatata atcgtagccc caaaattagg
    54541 aatcaaggct tatcaggtta agaaaagaag tgatgttgtt gatattttaa aacaatttat
    54601 ttaaactaaa aactctctat ctttttaaat tgacattaat ccgagattcc cctctcggat
    54661 tttgtgttgc tttcattaaa tttacaggta agccttgcta gcttcagtaa atatacacaa
    54721 gtttttcaga atagagtgaa atccaaaaga aaatggaaat aatgaaagct cttgtaggca
    54781 taagaaaaca cctctgtgtt atacttgttg ttcaaccaca aacacaagaa aggcacagag
    54841 atgcaaaacc attatactac aaaaggtaaa catttgacaa tcgatagccg tcgcttaatc
    54901 gaacgatgga aaaaagaagg
//
LOCUS       DAYYYC010000008        54440 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.008, whole genome shotgun sequence.
ACCESSION   DAYYYC010000008 DAYYYC010000000
VERSION     DAYYYC010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54440
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.008"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            60..527
                     /locus_tag="ACHBV5_000457"
     CDS             60..527
                     /locus_tag="ACHBV5_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966320.1"
                     /translation="MIDKVVRNLLLTFFFCKMTKIINFLTNILVKKKKICYNEFKLRN
                     RKQKGVIMWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRLLQEMIGK
                     EPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFDGE"
     gene            537..743
                     /locus_tag="ACHBV5_000458"
     CDS             537..743
                     /locus_tag="ACHBV5_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM9966321.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            743..940
                     /locus_tag="ACHBV5_000459"
     CDS             743..940
                     /locus_tag="ACHBV5_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966322.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQGDQFVWLYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            943..1677
                     /locus_tag="ACHBV5_000460"
     CDS             943..1677
                     /locus_tag="ACHBV5_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HFM9966323.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            1689..2330
                     /locus_tag="ACHBV5_000461"
     CDS             1689..2330
                     /locus_tag="ACHBV5_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFM9966324.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2348..2578
                     /locus_tag="ACHBV5_000462"
     CDS             2348..2578
                     /locus_tag="ACHBV5_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966325.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            2930..4693
                     /gene="aspS"
                     /locus_tag="ACHBV5_000463"
     CDS             2930..4693
                     /gene="aspS"
                     /locus_tag="ACHBV5_000463"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFM9966326.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            4671..5612
                     /locus_tag="ACHBV5_000464"
     CDS             4671..5612
                     /locus_tag="ACHBV5_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFM9966327.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(5654..5896)
                     /locus_tag="ACHBV5_000465"
     CDS             complement(5654..5896)
                     /locus_tag="ACHBV5_000465"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966328.1"
                     /translation="MKIKVQTRKLAAGCSKHCFEVVDRTDEVSSKHGFEVVDETDEVS
                     SKHGFEVADRTDEVSSKHGFEVADRTDEVSNIYTAR"
     gene            complement(6038..7024)
                     /locus_tag="ACHBV5_000466"
     CDS             complement(6038..7024)
                     /locus_tag="ACHBV5_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM9966329.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(7034..7834)
                     /locus_tag="ACHBV5_000467"
     CDS             complement(7034..7834)
                     /locus_tag="ACHBV5_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HFM9966330.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PGQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(8095..8937)
                     /locus_tag="ACHBV5_000468"
     CDS             complement(8095..8937)
                     /locus_tag="ACHBV5_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFM9966331.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(8939..10231)
                     /locus_tag="ACHBV5_000469"
     CDS             complement(8939..10231)
                     /locus_tag="ACHBV5_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFM9966332.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(10342..11613)
                     /locus_tag="ACHBV5_000470"
     CDS             complement(10342..11613)
                     /locus_tag="ACHBV5_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFM9966333.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            12148..13680
                     /gene="malQ"
                     /locus_tag="ACHBV5_000471"
                     /pseudo
     CDS             12148..13680
                     /gene="malQ"
                     /locus_tag="ACHBV5_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            13706..15964
                     /gene="glgP"
                     /locus_tag="ACHBV5_000472"
     CDS             13706..15964
                     /gene="glgP"
                     /locus_tag="ACHBV5_000472"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HFM9966334.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(17009..17581)
                     /locus_tag="ACHBV5_000473"
     CDS             complement(17009..17581)
                     /locus_tag="ACHBV5_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966335.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTTIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            17659..17865
                     /locus_tag="ACHBV5_000474"
     CDS             17659..17865
                     /locus_tag="ACHBV5_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966336.1"
                     /translation="MLKKYFSKYKWTDLFWILFVILTCLYIGNHDLFTLNHQEFSFRG
                     SFWGLVLALYHLLFIDKFVISNRK"
     gene            complement(18204..19052)
                     /locus_tag="ACHBV5_000475"
     CDS             complement(18204..19052)
                     /locus_tag="ACHBV5_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HFM9966337.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            19204..19482
                     /locus_tag="ACHBV5_000476"
     CDS             19204..19482
                     /locus_tag="ACHBV5_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HFM9966338.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            19484..21547
                     /locus_tag="ACHBV5_000477"
     CDS             19484..21547
                     /locus_tag="ACHBV5_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFM9966339.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIKLMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(21625..22881)
                     /gene="tyrS"
                     /locus_tag="ACHBV5_000478"
     CDS             complement(21625..22881)
                     /gene="tyrS"
                     /locus_tag="ACHBV5_000478"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFM9966340.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            23023..25488
                     /gene="pbp1b"
                     /locus_tag="ACHBV5_000479"
     CDS             23023..25488
                     /gene="pbp1b"
                     /locus_tag="ACHBV5_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HFM9966341.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            25553..26464
                     /locus_tag="ACHBV5_000480"
     CDS             25553..26464
                     /locus_tag="ACHBV5_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFM9966342.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            26694..27392
                     /gene="dapD"
                     /locus_tag="ACHBV5_000481"
     CDS             26694..27392
                     /gene="dapD"
                     /locus_tag="ACHBV5_000481"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFM9966343.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            27460..28590
                     /locus_tag="ACHBV5_000482"
     CDS             27460..28590
                     /locus_tag="ACHBV5_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HFM9966344.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            28602..29141
                     /locus_tag="ACHBV5_000483"
     CDS             28602..29141
                     /locus_tag="ACHBV5_000483"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFM9966345.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVVYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            29125..29802
                     /locus_tag="ACHBV5_000484"
     CDS             29125..29802
                     /locus_tag="ACHBV5_000484"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFM9966346.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(29874..30773)
                     /gene="galU"
                     /locus_tag="ACHBV5_000485"
     CDS             complement(29874..30773)
                     /gene="galU"
                     /locus_tag="ACHBV5_000485"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFM9966347.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(30795..31811)
                     /locus_tag="ACHBV5_000486"
     CDS             complement(30795..31811)
                     /locus_tag="ACHBV5_000486"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFM9966348.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            32302..32436
                     /locus_tag="ACHBV5_000487"
     CDS             32302..32436
                     /locus_tag="ACHBV5_000487"
                     /inference="COORDINATES: protein motif:HMM:NF037495.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966349.1"
                     /translation="MFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW
                     "
     gene            complement(32551..32982)
                     /locus_tag="ACHBV5_000488"
                     /pseudo
     CDS             complement(32551..32982)
                     /locus_tag="ACHBV5_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(33044..33694)
                     /gene="phoU"
                     /locus_tag="ACHBV5_000489"
     CDS             complement(33044..33694)
                     /gene="phoU"
                     /locus_tag="ACHBV5_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFM9966350.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(33709..34461)
                     /gene="pstB"
                     /locus_tag="ACHBV5_000490"
     CDS             complement(33709..34461)
                     /gene="pstB"
                     /locus_tag="ACHBV5_000490"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFM9966351.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(34463..35278)
                     /gene="pstA"
                     /locus_tag="ACHBV5_000491"
     CDS             complement(34463..35278)
                     /gene="pstA"
                     /locus_tag="ACHBV5_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFM9966352.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(35271..36134)
                     /gene="pstC"
                     /locus_tag="ACHBV5_000492"
     CDS             complement(35271..36134)
                     /gene="pstC"
                     /locus_tag="ACHBV5_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFM9966353.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(36252..37127)
                     /locus_tag="ACHBV5_000493"
     CDS             complement(36252..37127)
                     /locus_tag="ACHBV5_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFM9966354.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGKYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(37294..38625)
                     /gene="pnpS"
                     /locus_tag="ACHBV5_000494"
     CDS             complement(37294..38625)
                     /gene="pnpS"
                     /locus_tag="ACHBV5_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HFM9966355.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMVLTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(38626..39333)
                     /locus_tag="ACHBV5_000495"
     CDS             complement(38626..39333)
                     /locus_tag="ACHBV5_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFM9966356.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(39417..39903)
                     /locus_tag="ACHBV5_000496"
                     /pseudo
     CDS             complement(39417..39903)
                     /locus_tag="ACHBV5_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            39889..40447
                     /locus_tag="ACHBV5_000497"
                     /pseudo
     CDS             39889..40447
                     /locus_tag="ACHBV5_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(40762..42453)
                     /gene="argS"
                     /locus_tag="ACHBV5_000498"
     CDS             complement(40762..42453)
                     /gene="argS"
                     /locus_tag="ACHBV5_000498"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFM9966357.1"
                     /translation="MNTKELIASELSSIIDSLDQEAVLKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            42589..43035
                     /gene="argR"
                     /locus_tag="ACHBV5_000499"
     CDS             42589..43035
                     /gene="argR"
                     /locus_tag="ACHBV5_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFM9966358.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            43086..45620
                     /gene="mutS"
                     /locus_tag="ACHBV5_000500"
     CDS             43086..45620
                     /gene="mutS"
                     /locus_tag="ACHBV5_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFM9966359.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDCEGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            45767..47461
                     /gene="patA"
                     /locus_tag="ACHBV5_000501"
     CDS             45767..47461
                     /gene="patA"
                     /locus_tag="ACHBV5_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HFM9966360.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(47606..48061)
                     /locus_tag="ACHBV5_000502"
                     /pseudo
     CDS             complement(47606..48061)
                     /locus_tag="ACHBV5_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942960.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            48253..50019
                     /gene="patB"
                     /locus_tag="ACHBV5_000503"
     CDS             48253..50019
                     /gene="patB"
                     /locus_tag="ACHBV5_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HFM9966361.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAHQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPIMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            50158..50847
                     /locus_tag="ACHBV5_000504"
     CDS             50158..50847
                     /locus_tag="ACHBV5_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFM9966362.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            50851..51030
                     /locus_tag="ACHBV5_000505"
     CDS             50851..51030
                     /locus_tag="ACHBV5_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966363.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            51017..52366
                     /locus_tag="ACHBV5_000506"
     CDS             51017..52366
                     /locus_tag="ACHBV5_000506"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFM9966364.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            52490..53950
                     /gene="gltX"
                     /locus_tag="ACHBV5_000507"
     CDS             52490..53950
                     /gene="gltX"
                     /locus_tag="ACHBV5_000507"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFM9966365.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            53964..54398
                     /locus_tag="ACHBV5_000508"
     CDS             53964..54398
                     /locus_tag="ACHBV5_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFM9966366.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT        15957 a        10330 c        11841 g        16312 t
ORIGIN      
        1 aaccatacct acggcaaggt gaagctgacg tggtttgaag agattttcga agagtattaa
       61 tgatagataa agtggtcagg aacttactcc tgaccttttt cttttgcaaa atgacaaaaa
      121 tcataaactt tttgacaaat atacttgtca aaaagaaaaa gatatgttac aatgaattca
      181 agttaagaaa taggaagcag aaaggagtta taatgtgggt actaggattt atactattta
      241 tgattttctt ttattctaat aattctaaaa aaatcaagaa actagagaat aaaatcaaaa
      301 aacttgagcg aaaagagaaa ggaaacgcag aaatgtcgag attattacaa gaaatgattg
      361 gaaaggaacc aattataacg ggagtgtata ttgggccaga taactgggaa gttgtggatg
      421 ttgatgagga atgggtcaaa ctacgtagtg ttgataatac gggaaaagaa aaattcaagt
      481 tgcaacgtat tgaagatatc caaaccgttg aatttgacgg agagtaggtg tgtaacgtgc
      541 aactaaaaaa tcgtctaaaa gagcttcgag ctcgcgatgg tctcaatcaa accgacctag
      601 ccaaactggc aggggtttcc agacagacca ttagcctact agaacgggat gagtacaccc
      661 catccattat cattgccctg aaaatatctc aaattttcaa cgaaacagtc gaatcggtat
      721 ttcgtttgga ggaggacgag tgatgaacaa gtataaagtg atttattatg tagtggtcat
      781 agctttatta gtcagcgtat ttctactgat tgggatggac ctaagctggt ttaatcccta
      841 tcaaggcgac caatttgttt ggctctactt tgctctcatc ccagtaattg aatggattga
      901 aaagaaatcc aaaaatctag caagtgaaaa aggagaatga atatgaaaaa gaaacgtaga
      961 ttgttatttt tgatgtctat tgtcttgggg gggttcttgg gcatgtttgt agggatgttt
     1021 aaggcacgtg tcgaatccca cgaaattatt ttagatgtaa aagccttgat gccatggata
     1081 tcagctattt gtttactgat aggtttcatt agtatgtttt tgactttcaa tttcttaaag
     1141 aaaagcagaa aatttcattc cttgtatcaa gaggaaatgg atgacgatct gaatgaaacc
     1201 tattatgtgc aaatgtatcg gaatcttgag tttggaacca ttgcttttaa tattacaggt
     1261 gtagcgattc cattggctat ttttatttca ttaagtgagg tgattatatt gcatacaaac
     1321 cctcaaacat ttttcctttc tttcttactc tttgtggtat tcttagtcgc tcaaaaatct
     1381 ctttttaaaa ccattgcgat tgttcgtcag tttgatttgg aatttttcgc tacaccaaag
     1441 gatgtcttga actatataaa ttcttatgat gaaggggagc gtcaggctaa tttggaacag
     1501 agttttcgaa ttttattcca attacaccaa tatgtcttac cagccttata tatttttctt
     1561 attatcattt ctttcttgac aggagagatt cagttactag ctttcttgct tgtaggagcc
     1621 atccatgttt atatcaatgt gatgcagtta cctatggtaa aacgttattt caaataaagg
     1681 agttatctat gaaattactt aaaaaccttg gctggattct tctagccctt ctatcctttt
     1741 tatttatcta tggctttatt caggggctcg cgactgcgtc gcttgcttta ggcgcttcac
     1801 cctatgctgt tactctactc tatgtggcct tggctggagt atatgtgtac ggcatttaca
     1861 aatggtatca gaaggctcct gttcatattg agaagagcgg ctttaaccga tttatttggc
     1921 ttcctgcctt ggtttggttc ttatctctgg tcgttcaatt cttcttgcca gatgatcctt
     1981 cagtaaatca gcaaatagcg acagacttga ccttgtctca accacttttc tcattctttg
     2041 ctgtggttat ttttgctcct ttgacggaag agattgtttt tagagggatg ttagcacgct
     2101 atctctttcc taagcaggac aatagtaaac gaaccctgat ttttcttctg gtatctagtc
     2161 ttctatttgc cttgattcat tttccaggtg atgtgcaaca attttttgtc tattttagcc
     2221 ttggttttag tttgggcttg gcttacatta gcagaaaagg tctggtctac agtatttctc
     2281 ttcacgcttt gaataattta gtcggctttt tgatgattct catgctataa tagagtcagg
     2341 aggtcacatg aaacgagtaa ttttattagc agtgattcag gcagtcgttc tatttttcat
     2401 cattggagcg ctagcttatg ccttcaaagg cgatttcttc tataactatc tagcagttgt
     2461 ctttgctcct attgcaggtg tactgcgttt tgggacggct tacataacgg aaattgtctt
     2521 gcctcgaaag gcagccgaaa tcgctgaaaa gcgtaaagca ggcaaaaatt caaaataaaa
     2581 gagtccggtg aagttcatcg gatttttgta ttatactcaa tgaaaatcaa agagtaaact
     2641 aggaagctag ccgcaggttg ctcaaaacac tgttttgagg ttgtagatga aactgacgaa
     2701 gtcagctcaa aacatggttt tgaggttgta gatgaaactg acgaagtcag taaccatacc
     2761 tacggtaagg cgacgctgac gtggtttgaa gagattttcg aagagtatta gcgctaattt
     2821 ttagggcttt cacttgactt ttaaagactg gcaaactttt ctgatgattt tcatgaagag
     2881 cctgcgcttt tatggtaaaa tagtaacaga ataaaagagg agagaaataa tgaaacgtag
     2941 tatgtatgct ggtcgtgttc gtgaggaaca catcggacaa gaaataacct tgaaaggatg
     3001 ggttggccgt cgtcgtgacc ttggtggttt gatctttatc gatcttcgtg accgtgaagg
     3061 aatcatgcag ttggttatca accctgaaaa agtatctgca gaggttatgg caacagctga
     3121 aagccttcgt agcgaatttg ttattgaggt gactggtcag gtcgctgcgc gtgagcaagc
     3181 caatgataag ttgccaactg gtgcggttga gttaaacgtg acagctctta ttgtgcttaa
     3241 cacagctaag acaacaccat ttgagattaa ggatggcatt gaggcaaatg acgatacacg
     3301 tttgcgttac cgttaccttg accttcgtcg tccagaaatg ttggaaaatc ttaaacttcg
     3361 tgccaaggtg acccactcta tccgcaacta tttggatgag ttggagttta tcgacgtgga
     3421 gacaccattc ctttctaagt caacgcctga aggggcgcgt gattatttag tgccgtctcg
     3481 tgttaataag gggcattttt acgctcttcc tcaaagtcca caaatcacga aacagctctt
     3541 gatgaatgct ggttttgacc gttactacca aatcgttaaa tgtttccgtg acgaggactt
     3601 gcgtggagac cgccagcctg aatttactca ggtcgacttg gaaacgtcct tccttactga
     3661 gaaagaaatc caagatatta cagaaggctt gatcgcgcgc gtgatgaagg aaacaaaagg
     3721 catcgaagta acgctaccgt tccctcgtat gaaatacgat gatgctatgg ctctttacgg
     3781 ttctgacaag ccagatactc gttttgacat gttgcttcag gacttgacag aagtggtcaa
     3841 aggtgtagac tttaaagtct tttcagaagc acctgctgta aaagcgattg tggtcaaagg
     3901 agctgcggac aactattcac gtaaagacat cgacaagatg acggaagtag ccaaacagta
     3961 tggtgccaaa ggtcttgctt gggtcaaggt ggttgatgga gaattaaacg gaccagttgc
     4021 caagttcttg actggtatcc aagaagaatt gacaacagcg cttgctcttg aagataagga
     4081 cttggttctc tttgtggcgg atacgcttga agtggctaat gcaacactgg gtgcccttcg
     4141 tggacgtatt gctaaagagc ttggcttgat tgataatgat aagttcaact tcctttgggt
     4201 ggttgactgg ccgatgtttg aatggtctga agaagaaggc cgctacatga gcgcccacca
     4261 tccattcaca cttccacagg aagagactgc tcacgaatta gaaggtgatt tggctaaggt
     4321 tcgtgccatt gcttacgata tcgtcttgaa cggttatgag cttggtggtg gtagccttcg
     4381 tatcaaccaa aaagaccttc aagaacgcat gttcaaggct cttggtttct caactgaaga
     4441 agccaatgac cagtttggtt tccttcttga agccatggac tatggtttcc caccacacgg
     4501 tggtttggct atcgggcttg accgttttgt catgttgctt gctggagaag aaaatatccg
     4561 tgaagtcatt gcctttccta agaacaacaa ggcaactgac ccaatgacac aagctccatc
     4621 aacagtcgct ctcaaacaac tagaggaact cagcttacaa gtagaagaag atgaaacaaa
     4681 caaaacgaat taagcggtgg cgctattatc tgcgccgctt tgcttatcag ataaaaattt
     4741 tacgtgtctt acaaagtatc tctcgagaaa agtatgatga gaagatttcg gcctctctgg
     4801 tctatggttt tttatcagca gtagcagtta atttcttttt ccaaccaggg catgtgtatt
     4861 cgagtggtgc aacaggtctg gcacagatta tctctgcctt gagtaatcac tggtttggtt
     4921 ttcatattcc gatttcgcta agcttctacg ccattaactt ccctttgatg gtcttagctt
     4981 ggtatcagat tggccataag ttcaccgtct ttacctttat cacggtatct atgagttcct
     5041 tctttatcca gtttgtccct gtggcaacct tgacggagga tcccattatc aattcccttt
     5101 ttgggggtgt tgttatgggt ttggggattg gttttgctct tcgaaacaat atctccagtg
     5161 gtgggacgga tatcgtcagc ctgactattc gcaagaaaac gggtaagaat gtcggtagta
     5221 tttctttctt ggtaaatgga actatcatgc tgatagcagg tttgaccttt ggttggaaat
     5281 acgctcttta ttctatgatt accatctttg tctctagccg tgtgacagac gcagtcttta
     5341 ctaagcaaaa gcgtatgcag gccatgattg tgacaaatca tccagagaag gtaattgaaa
     5401 aaatccataa aaaattgcac cgcggagcaa ccatgatcca cgatgcagaa ggaacctata
     5461 atcacgagag aaaggcagtt ttaatcactg tcattacacg tgcagagttt aatgaattta
     5521 aacagattat gacacaagtg gatccaagct cctttgtctc tgtctcggaa aacgttcata
     5581 ttctaggaag atttgttgag atagataatt agtgattaat actcttcgaa aatctcttca
     5641 aaccacgtca gcttcacctt gccgtatata tgttactgac ttcgtcagtt ctatctgcaa
     5701 cctcaaaacc atgttttgag ctgacttcgt cagttctatc tgcaacctca aaaccatgtt
     5761 ttgagctgac ttcgtcagtt tcatctacaa cctcaaaacc atgttttgag ctgacttcgt
     5821 cagttctatc cacaacctca aaacagtgtt ttgagcaacc tgcggctagc ttcctagttt
     5881 gcactttgat tttcattgag tataaaaaga tcttgggaaa agactcaatt tcagtagaaa
     5941 aggaagtaaa tcttcccaca ataaaacgca tagtatcaag ttttttcaat acctgatagt
     6001 atgcgttttt gcttttaacg actctttgcc cagtctctta tttttcgata attttgtggg
     6061 cgatcaattg acggtaacaa atttgtttat tgtttttatt atcattaata atctggagaa
     6121 tagtttcaag ggaaacacga ccaagctcta aactattgat atcgacatag gctgccaagt
     6181 tgagcttggg attaaccgag tcaaagctga gaacagggac atccagctgg tgtttggcaa
     6241 tatagttaca aacaccttca gctaggaggc tatcggttgt gatgatagca tcaatttgtg
     6301 gatcgtgctt gaataatcgc ttgctaaatt tatagccctt ttcttccaga aactcgtcgg
     6361 caaagtagat gcgattgttg tcagtggtaa gtttgtaatg tttaagcgcc tgttcatagc
     6421 ccgttaaacg gtctttggtc acgaagagct ttttacttcc tccgataaag gcaatgcgtt
     6481 tgcagccttt tttgatgaaa tattcagtcg catcaaaacc agcttgaaca ttgtcgttgt
     6541 cgacaagtgg gatgaaagga gatagagatt tacctaagat aaggaagggg aactgttctt
     6601 ctgcgacgag ttttacgaga gggtcttctt cttgggcata gagaaagatt agcccatcta
     6661 cacgcttgcc gtagaccatt tgtgaaatag cgttgagacg ctccttctca tctttccctg
     6721 ttgctatttg aatggcatag tggttttcag atgcgacttg agagatgcca cgtagaaccg
     6781 atggaaagaa aggattctgg tagaaggcgt ctgagtcatc aggaagaact aatccgataa
     6841 cctgagtata gctgcttacc aagctacgag cgttaaggtt tgggtggtag ttgagttcct
     6901 tcatagcttt gcgaacgcgt ttttttgttt cgtcgctaat ggttgattta ttttgaataa
     6961 cacgggttac ggttgaaggc gaaacaccag cagccttggc cacgtcttta atcgtaacgg
     7021 gcataaaaat ctcctattta tggtaatttg gatcacggaa atgtgtttta taaaagatag
     7081 tgaccagata cagaacaaaa agaatatttt gtacagtaat cagggttgtc atattttggc
     7141 caaataatcc caaaataagt gtaatcagag tcggcaatcc taaacagttc aagataaagt
     7201 gatagcactc tttaaaggtt ctaaatgaaa agaggcgtga tttcttagtg atataaagga
     7261 gaagactagc tcctagagag acgataaaga aattcaaacc aaagaggaag ctcgcaccga
     7321 gaactaggaa gaggctgata tagacacgat tttgttggta ccagtcttta gaaattgctt
     7381 gggtcaagct gtctttgctt ttgaaactct cagtctgaat ggctcggtaa gagatgcggg
     7441 tcagttcctt gctttccttg ctgatgacta gttcatttgt atcgaaatgc agttgcaagt
     7501 ccttaggtaa ttccttgatt tgacctggac caatcacaac agaaggggct tgactagctg
     7561 ttccagtata agttaatgtg ccatcgacaa ttgtagcatg ttcagagaga tcctggacaa
     7621 cctcatttgt cagaggttca tagacattat cgataaaagt ttctagcgga taggtctcct
     7681 gggagctgtt ttggatagca atgggtacca tagacaagct gataaggaag atactggtaa
     7741 agagaagttg aaaccagttg agctcgaaac gtttggacag gggcttacga aacccccaaa
     7801 tacttgaaaa ataggaaaat ggatatggaa gcataggtat ctttctaaaa ggtgttttct
     7861 atatgagtat tattatatag agaaatgcgc tttatttcaa gtctaggggg taaattgctt
     7921 gctacaagga tattatttac agtgacaatc gctaatagtc aatgaaaatc aaagtgcaaa
     7981 ccaggaagct agctgcaggt tgctcaaagc acaactttga ggttggagat aaagctgacg
     8041 tggcttgaag agattttcga agagtataaa atgaaaaagg gtggcgggga taaattatcc
     8101 cttgtcgcca ccacttgtaa gtcctgaaac aaagttcttt tgtaggaaga agaagagaat
     8161 acagattgga agggcgatga ggatagcacc tgctgagaag taggcaatct tcaagttttt
     8221 cgcattgtta acgaaggttt ggagacctac ggcaacagta aagtattctt tctcacgaag
     8281 caagaaacta gagaggatgt agtccccgaa aggtcccatg aaggcccaga gagcttgtac
     8341 ggcaaccatt gggcgaacaa gtggtagaac aatttgccag aagcggcgga agtgtcctgc
     8401 accgtctagt tttgcagatt cgtctaaaga cattggcact gtatcgaagt agcctttcat
     8461 gagccaagca ttcatcggga taccaccacc aacgtagagg aagatgagga accagttgtg
     8521 gttaagggcg ttcaacataa gcgccataac gaagaaggct gtcaaagcgg ccatagttgg
     8581 caccatttgg atgatcaaga agaagaccaa actttgttta cgagccaaga agttgtaacg
     8641 gctgtaagca taaccagcaa gtacgatgat acttgtttga acagccatgg taattaaggc
     8701 gataatcaaa gtgttgaggt accaagtacc gtacaaggtt tcagtgaaga ggcctttaaa
     8761 gttatcaaaa ttgaggtcga tattagtatc tagtttaaag gctgagacgt tacctgcttt
     8821 aaaggctgac atgatggtaa tcaacagtgg atagataatt acaattgata gaccaatcag
     8881 gtaaaggtaa gtaaggcttt gagtcagtct acgtttgagt ttaattgagt tattcatctt
     8941 agacgtcctc catatcaaat gcgtgtagtt tcttgaatgc gatcatagag attgagatga
     9001 caatgataga gataatcaag gtaacagctg ccgccattga gtattgagga gatgtacctg
     9061 ttgtcaaacg gtagatccat gagatcaaga tatcggttga accagctcca cctccgacac
     9121 taccaggtcc tccaccattg aagaggtaca tgatagagaa gttgttaaag ttgaaggtgt
     9181 attggctaat caaagtaggt gccgcaacag ccaaaatcat tgggaaagtg atgttgcgga
     9241 atttttgcca agcgttggca ccgtcaatat aagctgcttc gtaaaggtcg ttaggaatag
     9301 attgcaagat acccaaagtc aaaacgtaga tgtatgggaa tccgagccaa ccttgcatca
     9361 taatcaaggc aatcttagtc caagttgggt ctgttttcca aggaataaga gctccatcaa
     9421 ggaaaggaag gaatttagcc aagattggca atacttgagt gttgatagca ccgacactat
     9481 cgttaaacat gtttgagaat gtcaagatag tgatgaaggc tgggacagcc caaggaagaa
     9541 ggaaaataac accaaagata cgttttcctt tgataaatgg ttggttggca atgatagctg
     9601 tgaagatacc aattacgatt tgtaaagtag aagctgccaa agcccaaatg atagtccaag
     9661 aaagaacaga accaaaggca gaacggaagg tactcaagct ccaaatgttt gtaaagttgg
     9721 tcaaaccaac ccagtccaac aacttgtttg gtggcaagtg ttggaagtcg tagttggtaa
     9781 aggcgatcat caaggttacg ataactggga agataatcgc gaaggtcatg gcaacataag
     9841 atggaatgat caagaggtaa gggaagccat tttcataaat ccctttgatc atgtctttga
     9901 gtgtgcgtgg aactggaatt ccattgttaa tgcgttttgc aatcgtatgt gcatctttga
     9961 tatttgagaa ataaaagagt acataaacga ttacaaagat tagatggaag gcaccacgaa
    10021 tcagcataaa gagggaatta tcacgacctg gtttgtcacc aagagtgatg aggttgctca
    10081 attcaggggt tgcaagtgct aggaagtaaa ggacaaatac gatggttaca ccaaggaaga
    10141 taaaaccttt ggctttttgt ttattgtaaa tctgtcctaa cccaggaatg atagacagca
    10201 gggctgcttt actaggttgt tgcttttcca tattaactcc tttcatagga tactactttt
    10261 ttataagaaa gctaaattat ttgtgtctct attgataaat tcaaaggggg atttgatttc
    10321 cacccccctt gaacaaattt tttattcacc aaatttttgt ttgattgttt ctttgatcaa
    10381 tgttacagca tcgttagcag ctgttttagc atctttttga ccacttacag catcaaagag
    10441 catatttttc gctggatccc aaactgcaga catttgagag atgtttggca gtggttgagt
    10501 gttcttgaac tgtttgataa cagctgttgt caactcatcg tttttacctt cagcgtatga
    10561 acgagcctca gtattagctg ggatttcgtt agtcttatca tataatactt tttgttgttc
    10621 agttgcaaca aggaagtcta caaatttttg agaagcttca aggttcttaa cggcttgagg
    10681 aatgacccaa gctttaccac caccgaatgc agcatattct tttccatttg gaagagttgg
    10741 gatagttgca actccgtagt ttactttagc atctttaaag gcttgagctt tccaaggtcc
    10801 gtcgatgata gcagctgttt taccttcttg gaattgagtt tggattaagt ttccagcacc
    10861 ttctgtatct tgcatacctt taggccattt ttcgtaccaa gatttagcgt agttgatacc
    10921 tgcgatagaa ccgtcgtttg caagaccgat gtctttagcg tctttaccgt tttggccaaa
    10981 gacgtaagca ccgttaccgg caagaagtcc atatgtatag tagaagtttg tccagtcagc
    11041 taggaaggca gtagttttac catcttcacc agcgaatgcg tatttgctat ctttagcaag
    11101 gttttccaag tcagcaaatg tttttggagc atctttcacc aagtctttgt tgtagtacat
    11161 aacaagtgac tcgataacgg caggagcacc gtaaacttta ccattagcag ctgttacaag
    11221 agatttagtt gtgtcgtctg ttttagcacc atcgctcaat ttcacttctg aaagttgtcc
    11281 gtcagaacca aggctaccta cacggtcgta tggagccatc ataacatcag ggacattacc
    11341 agattggttg tcaagagaaa gtttatcaag acctcctaga gcatcaccag ttttaagagt
    11401 gacttttact ccagcttctt tttcataagc tttagcaacc tcttcaatat agctcttata
    11461 tccctcgtct acatatacag tgagttcttt gacttcagat gaaccagaat cagcaggctt
    11521 atcagcagtt ttgcttccgc aagctaccaa aagcaagcta gcaagtgtag cagttccaag
    11581 caccgcagtg ctcttcataa atttagatga catagtgtat tcctcccaaa gaatagcaag
    11641 ttttattgat aaggaaacgc aaacgttttc ctttatgagc ttagtatagc acaaatagaa
    11701 aacggttgca agtatttttt gtaaaaattt taaaaaattt ttaagcttga tttgatagca
    11761 taattttgca ttttaataga agaaaagtat gaaatagata agaatacagt atttttaata
    11821 aaaatatatg gaatctgtct aaagagggaa atcaggaggg gctacctccc tgtttctaat
    11881 ccctatctat tttctataga cgtttgtgct ttgttgcata taaattcaag ctccctaagg
    11941 aggttttgta ctttgtagac tgtctcgtga gagtcaaact ttaggattag atagttttaa
    12001 gttatctttg ctaaaatgag ttagtctcct taaaaataat caaaaaagtt ttttaaaaac
    12061 gcttgcaatt atgcttgaaa aggagtatac ttataagtaa cgcaaacgtt tgcgtctgca
    12121 aaatacgcaa cgttccatta ttttaacaca cgaggtgcta ttatgaaaaa acgtcaaagt
    12181 ggtgtgttga tgcacatctc ttctcttcca ggagcttacg gaatcggatc atttggtcaa
    12241 agtgcttacg acttcgttga tttcttggtc cgtacaaaac aacgttactg gcaaatcctt
    12301 ccattaggag caactagtta cggggattct ccttaccaat ctttctcagc cttcgcagga
    12361 aacactcatt ttatcgattt agatatcttg gtggagcaag gtttgttgga agcaagtgac
    12421 cttgaaggag ttgactttgg tagcgatgcg tctgaagttg actatgctaa aatctactat
    12481 gcacgtcgtc ctcttttaga aaaagcggtg aaacgtttct ttgaagtcgg agatgttaaa
    12541 gattttgaga aatttgctca agacaaccaa tcatggcttg agctctttgc tgagtatatg
    12601 gctatcaaag agtattttga caatcttgct tggactgaat ggccagatgc agatgctcgt
    12661 gctcgtaaag cttcagcact tgaaagctat cgtgagcaat tggcagacaa gttggtttac
    12721 caccgtgtga ctcaatactt cttcttccaa caatggttga aattgaaagc ttacgctaac
    12781 gacaaccaca tcgaaatcgt tggggacatg ccaatctacg tagcggaaga ttcaagtgat
    12841 atgtgggcaa atccacatct cttcaaaaca gatgtcaatg gtaaggctac ttgtatcgca
    12901 ggatgcccac cagatgagtt ttctgtaact ggtcagcttt ggggtaatcc aatctatgac
    12961 tgggaagcaa tggacaaaga cggctacaaa tggtggattg aacgcttgcg tgaaagcttc
    13021 aaaatctacg atatcgttcg tatcgaccac ttccgtggct tcgaatctta ctgggaaatc
    13081 cctgctggtt ccgatacagc agcacctggt gagtgggtga aaggtccagg ctacaagctt
    13141 tttgcagccg ttaaggaaga acttggtgag ctaaacatca tcgcagaaga ccttggcttc
    13201 atgacagatg aagtgatcga attgcgtgaa cgtactggct tcccaggaat gaagattctt
    13261 caatttgcct tcaacccaga agacgaaagc attgatagcc cacacttggc acctgctaac
    13321 tcagttatgt acacaggaac acacgataac aatacggttc ttggttggta ccgtaatgag
    13381 attgatgatg cgactcgtga gtacatggct cgttacacga accgtaaaga atacgaaaca
    13441 gtggtacacg ctatgcttcg tacagtattt tcatcagtta gctttatggc aattgcaact
    13501 atgcaagatt tactagaatt ggatgaggca gctcgtatga acttcccatc tacccttggt
    13561 ggaaactggt cttggcgtat gactgaagat caattgacac cagctgtcga ggaaggtttg
    13621 cttgacttga caacaattta tcgccgaatt aatgaaaatt tggtagattt aaagaaataa
    13681 gacaataatc aggagacaac taaacatgtt atcactacaa gaatttgtac aaaatcgtta
    13741 caataaaacc attgcagaat gtagcaatga agagctttac cttgctcttc ttaactacag
    13801 caagcttgca agcagccaaa aaccagtcaa cactggtaag aaaaaagttt actacatctc
    13861 agctgagttc ttgattggta aactcttgtc aaacaacttg attaaccttg gtctttacga
    13921 cgatgttaaa aaagaacttg cagctgcagg taaagacttg atcgaagttg aagaagttga
    13981 attggaacca tctcttggta atggtggttt gggacgtttg gctgcctgct ttatcgactc
    14041 aattgctact cttggtttga atggtgacgg tgttggtctt aactaccact ttggtctttt
    14101 ccaacaagtt cttaaaaaca accaacaaga aacaattcca aatgcatggt tgacagagca
    14161 aaactggttg gttcgctcaa gccgtagcta ccaagtacca tttgcagact ttactttgac
    14221 atcaactctt tacgatattg atgttactgg ttatgaaaca gcgactaaaa accgcttgcg
    14281 tttgtttgac ttggattcag ttgattcttc tattattaaa gatggtatca actttgacaa
    14341 gacagatatc gctcgcaact taactctctt cctttaccca gatgatagtg accgtcaagg
    14401 tgaattgctc cgtatcttcc aacaatactt catggtttca aacggtgcgc aattgatcat
    14461 cgacgaagca atcgaaaaag gaagcaactt gcatgacctt gctgactacg cagttgtcca
    14521 aatcaacgat actcacccat caatggtgat tcctgaattg attcgtcttt tgactgcacg
    14581 tggtatcgag cttgacgaag caatctcaat tgttcgtagc atgactgcct acactaacca
    14641 cacaatcctt gctgaggcgc ttgaaaaatg gcctcttgaa ttcttgcaag aagtggttcc
    14701 tcacttggta ccaatcatcg aagaattgga ccgtcgtgtg aaggcagagt acaaagatcc
    14761 agctgttcaa atcatcgatg agagcggacg tgttcacatg gctcacatgg atatccacta
    14821 cggatacagt gttaacgggg ttgcagcact tcatactgaa atcttgaaaa attctgagtt
    14881 gaaagccttc tacgaccttt acccagaaaa gttcaacaac aaaacaaacg gtatcacttt
    14941 ccgtcgttgg cttatgcatg ctaacccaag attgtctcac tacttggatg agattcttgg
    15001 agatggttgg caccatgaag cagatgagct tgaaaaactt ttgtcttatg aagacaaagc
    15061 agctgtcaaa gaaaaattgg aaagcatcaa ggctcacaac aaacgtaaat tggctcgtca
    15121 cttgaaagaa caccaaggtg tggaaatcaa tccaaattct atctttgata tccaaatcaa
    15181 acgtcttcac gagtacaaac gccaacaaat gaacgctttg tacgtgatcc acaaatacct
    15241 tgacatcaaa gctggtaaca tccctgctcg tccaatcaca atcttctttg gtggtaaagc
    15301 agctccagcc tacacaatcg ctcaagacat tatccattta atcctttgca tgtcagaagt
    15361 tattgctaac gatccagcag tagctccaca cttgcaagta gttatggttg aaaactacaa
    15421 cgttactgca gcaagtttcc ttatcccagc atgtgatatc tcagaacaaa tctcacttgc
    15481 ttctaaagaa gcttcaggta ctggtaacat gaaattcatg ttgaacggag ctttgacact
    15541 tggtactatg gacggtgcta acgtggaaat cgctgagttg gttggagaag aaaacatcta
    15601 catcttcggt gaagattcag aaactgttat cgacctttac gcaaaagcag cttacaaatc
    15661 aagcgaattc tacgctcgtg aagctatcaa accattggtt gacttcatcg ttagtgatgc
    15721 agttcttgca gctggaaaca aagagcgctt ggaacgtctt tacaatgaat tgatcaacaa
    15781 agactggttc atgactcttc ttgacttgga agactacatc aaagtcaaag agcaaatgct
    15841 tgctgactac gaagaccgtg acgcatggtt ggataaagtc atcgttaaca tttctaaagc
    15901 aggattcttc tcatctgacc gtacaatcgc tcagtataac gaagacatct ggcacttgaa
    15961 ctaatactct tcgaaaatct cttcaaacca cgtcagcttt atctgcaacc tcaaagcggt
    16021 gctttgagca acctgcggct agcttcctag tttactcttt ggttttcatt gagtataaga
    16081 tacaaattta tactaataca ttttgtaaaa aagcgagttt cgattgaaat tcgctttttt
    16141 aaatgctgta gatttgggtc aatcttgtct aaaaataggg aaatcctaga tacagtgaag
    16201 actttaaatg ctggttttta ctgtcctcag ccttatattt tttcgtagtt gattacctca
    16261 cacctcttgt attcgcttac ataaagtatt ataatataat tgtaggaaag aaggtgtttt
    16321 tatgatatac acacttaaat tggtgttgtt tattaccttt cttgtaataa gcttgttacc
    16381 tgataagatt tttggaaaaa ataaaaaaat ttggaaaata gtttttgcaa tattgacggc
    16441 agtggcagca ttgtcattta tgtactaagt tattttaaga atgtagggaa ataaacccta
    16501 cattcttttt agttttttct gttttctaaa ttctatttat ccaagcgctt caacatttct
    16561 tgcttcttcg cttcaagttc tgcacgcttt tcttcgattt cggcatgttt tttctcgagt
    16621 tcagaacaac ttgcaccatt gctaaattct tttcgccatc aggagatagg gtgagtcgac
    16681 atgtctatta ctcacccaaa gcagtcctac aaagcaggaa ttttctgtta cttttttgga
    16741 aatagtaacg tttatacagc tttgacactt cgtatcaaag cgccaaacac actccgaggg
    16801 atttacagaa agcagaaaag gaatgatctg gtataagatc attccttttc tctctttttc
    16861 tttaagtaat tatatacaat gtacgacgaa gtcgtcattg caatgctgat ccaccaccta
    16921 aagggaactt taaacaacat tgataagata aagaatataa acaacgaaaa tacgttatac
    16981 ccaattaatt ttattgtata tctcatgatt aaaagttaat ccttccgttg ttaggaatgg
    17041 catcattttt atcccataat tgtgctaaat aagtccccgg tgataataaa ttcatagcgg
    17101 attctaaagc aacatcattt acaaaccaac tacctagata tctagaaatt gctgaacgaa
    17161 tagcactttt tgctgcatgt tttcctttta ctttaattag atttgcaagg cctgcagtag
    17221 ttcctcctaa tgctaaagct attgtagtat ctaatagagc acccatttga ttaactgtaa
    17281 taccttgcca agctgctcta aatggagagt atgtaggtgg gattgtataa tcgccttgta
    17341 attgtcggtt aattacttct ttgatccatt gttgtgagac gtctggatga aaagattgga
    17401 tttcgtttgc aagtgtattg atttgttctt ctgttagaga agtgacaggt tgaagttcca
    17461 tatttgtttc aatttgcgat acttgttcag aagcgtatac agctgaaaca cttggaatcg
    17521 ctgatacaat taacacaatt gacgtcaaaa aaaccgaaat aaatttcatt aatttgttca
    17581 tgagcttttc tcctttttat ttgtatctgc ttacatttta ttatatactg ttattatagt
    17641 caagaaaaat atgctattat gttaaaaaaa tatttttcaa aatataaatg gacggattta
    17701 ttttggattt tatttgttat tttgacctgc ctctatattg gtaaccatga tttgtttact
    17761 ctcaatcatc aagaattctc ttttcgtggt agcttttggg gtttggtact ggccttatat
    17821 cacttattgt tcattgataa gtttgtaatt tcgaatcgaa aataaagatt agaactatga
    17881 ttgactggct acttttaata ttgattttgg aggaagattt tgtctctatt atttattatt
    17941 ttaaatttat ctattttgta caatatctat tctttgagac gggagaaatc gaaatacttg
    18001 atttatacgg cctatatcat atttggggta aatgtagtat atggtattca atggttatta
    18061 agagaactga tttcaactat ttccccttaa tgtgtatgga aactataaca aaacgcataa
    18121 gattaaggtt tgtgtacctg ttcttatgcg tttttgtaat attgaagatt ttcggtaagt
    18181 tttatacctt tgggaagtct agtttagaat gctttcccaa ccagaatctc tgcttcgatg
    18241 gtaatctctg tcagttggct ccagtcaatc ttgctctggt caacatgaaa gaggagagga
    18301 gtcatactga gtagggcttg gagttgttct gctgtgatag tcttagtcag agaggcagtt
    18361 tgactagata ggatggtaaa gtgttcctgg aaatgctcct tgatatcttg gttagaatac
    18421 tccttgtttg tcagctggtc ctgtactctt tgacggattt ctttgaggtg attttcagtt
    18481 gggataacct ttatcaagat accgtctttg gataaaacgc gacgaaattc tccatagttg
    18541 gcaggtgaga agatatcaag cagaatatcc atgttagcgt cttttatagg aagtcgtgcc
    18601 aagtcgccaa cgaaccaatt gactgcccag ttgggttcac ttttagcagc gatttggact
    18661 gaatctttgg agatgtcaaa ggcatagaaa gttttttcag agtgactttc ttgtagtttg
    18721 cgagaataga atccttcacc acaaccgata tccaaaattg ttgtggtagt ttttgagctt
    18781 gcaagcaagt cagatacagc atctaagata gcttggtaaa agccggcttc taggatttgt
    18841 tgacggtttt gaaaattttc cttgtcatag ttagcagatt gcttgatttg aggtgctaga
    18901 ttgacatagc caaatttcgc caagtcaaaa gaatgacggt tgcagcactt gaaattagtc
    18961 tctaacagag tcagattttc ttgacagata ggacaggcaa aggcagtcgc agaagcaaaa
    19021 cgctgaagtt tgggcttgag atttgtattc atagtttaag tgtatcaaaa gaggcaaatg
    19081 aaagcaactt taggaataag tagatgggag attcagtaga aataaaacta attctccaat
    19141 ttatagaatg aaattgcttt tatatctaaa ttgctatata ataatgataa ggaggaaata
    19201 agtatgttaa aagaagtatt aaccgttgca aaagttgcga aaaaatcttc attatttttg
    19261 ggtggtgtcg catttggtac ccttggtttg aaaatcttag caagtaagga agctaaaaaa
    19321 ggttattcta aagctttggc taaggcttac aagttgaaag acgagctaga tgcatctgtt
    19381 tctgttgtga agcaacatgg agacgatgtc ttgcaagatg ccaaatattt gtacgagcaa
    19441 gagaaaaaag aagagcaatt agatagcctt ataggtgaat aatatgtctt ttaaagtgct
    19501 acatagagga taccaacata tccgactatc atcttctttt tcacttacct tggatattca
    19561 agactatctt cgttccttgg cgagagatga aaaggggatt gagtctatcc agttttacat
    19621 ggatcaacag cactttactc tacgcataaa agaaggcttt tctgtattag ataatgcaga
    19681 agccttttta aaaagaattg ataaagggaa agtttctgag ttgatgactc ttcccattcg
    19741 tagagaagag agtgcttatt ctattgtttc aggtgcagcg gttaagcgtg tactttttcg
    19801 tagttttgtg ccgtatccta ttcgctatat atggacttgt tatcaggctt tgggttatat
    19861 tagagaagcc tatcaaacac tagcgcgtaa ggaactaacg atggaagtct tggactgttc
    19921 ggctatttta ttgtctttgt ttatgaacca atccaagaca gctagcaata tcatgtttat
    19981 gcttgatttg gggaatcatt tagatcagtg gtccttgaaa aaaactgcaa cagatttaga
    20041 acagagtctt cttgcaaaag agagcgatgt attcctagta cagggcgata cggttgttag
    20101 tatcaagagt tccgatgttc aaataggaga tgtcttgatc ttatctcaag gaaatgaaat
    20161 tctgtttgat ggacaagtag tttcaggttt aggtatggtc aacgaaagtt ccttgacagg
    20221 agagagtttt ccagttgaaa aaagagagtc tgatttggtt tgtgcaaata cagtattaga
    20281 aactggagag ttacgcattc gtgtaacaga taatcagatg aacagccgta ttttacagct
    20341 gattaagttg atgaagaaat ctgaagaaaa caagaaaacg aaacaacgct atttcatcaa
    20401 gatggcggat aaagtcgtta aatataattt cttgggggct gggctgactt acctattgac
    20461 aggttctttt tctaaggcta tttctttcct attggtcgat ttctcctgcg ctttgaaaat
    20521 ctctactcct gtagcttatt tgacagttat caaggaaggg ttgaaccgtg aaatggtgat
    20581 taaggatgga gatgttctgg agaaatatct ggaagttgat actttcttgt ttgataagac
    20641 aggaacaatc acaactagtt atcctatagt tgaaaaggtg ttaccttttg gagactatag
    20701 tgaggaagat attctcagaa tcagtgcctg tcttgaggaa cacatttatc atcctattgc
    20761 taatgccatc gtcaagcaag ctgagataga gggaattgaa catgaggaaa tgcatgggaa
    20821 actccaatat atcgcaagca aggggatcaa atctcatata gatggccaac cagttcttat
    20881 tgggaattat gtcttgatgc aggatgagca gattcatatc agttcagaac aaaatgcttt
    20941 aattgaagag tacaagagtc actacaatct cttattcttg gcttatcaaa atgaattgat
    21001 tggaatgttc tgcattcata ctcctttgag aaaagaagca aaaacagcct tggataaact
    21061 taaggcacag gggaaaaaat tgattctggc aacaggagac accttgatta ggacagagga
    21121 attagtcaaa gatttgccct ttgatcaggt ctatacagac ttgaaacctg atgggaaatt
    21181 tgagttagta gagaaactgc agaaagcagg tcacactatt ttgatggttg gagatggatt
    21241 gaatgactca gcggctttaa ctctatcaga tatcggtgtg gtgatgaatg agagtgcaga
    21301 tatttctaag cagatgagtg atatcttatt gttagataat cgtttggatt tcttccaaga
    21361 gttggattcg ttatcatcat ctttgcaaac actcatcaag aaaaatattc aagataccgt
    21421 tgtcgtaaat agtagtttga ttggctttgg cttatttaat tggctcagtc cttcaaatct
    21481 ctctatctta cataatctaa caaccttgcg cattgtcctg cgtagcctgt ctattaaaaa
    21541 tagatagatg agagttatta acagcaaaaa ggagttacct ttctcgaggt taactccttt
    21601 gtttatagat aaatgttgaa tggtttagta agtcaataca aagtattttt tcttcccacg
    21661 acggataaca gtcagttcat tttctaactt atcagcgtca ctcaagacat agtcaaggtc
    21721 ttggatgcgg tcgccgttta cgtagatggc tccgttttgg acgtcttcac gggcttggcg
    21781 ttttgagtta actataccag atgagacgag cagttccacg atattgttgt tttcgtctgc
    21841 ctgtacttgg tagtttggca caccacgaag tccttgtttg agctctttga cagaaaggtt
    21901 tttgatgttt cctgcaaaga gttgctcagt gatgttaagt gcttctttgt aggcttcttc
    21961 tccgtgaaca agtgtaacaa cttcacgagc caagactttt tgagccaagc gttcgtgtgg
    22021 cgctgcttca aattgtttac gaatatcttc aatctcatca agtgacaaga aagtaaagat
    22081 tttcaagaag cgaacagcgt cagcgtccat cacgttcatc cagaattggt acatttcgta
    22141 tggagaagtc ttttcgggat tgagccagac ggcatttcct tctgatttac caaatttttt
    22201 accagttgca tctgtgatta gtggaacagt gataacgtga ccagtcttgt ccgccttacg
    22261 acgaagcaat tcggtaccag ctgtcatatt tccccactgg tcagaaccac cgatttgaag
    22321 agtgacatta tggtcttggt taaggacgaa gaagtcgtac ccttgcatga tttggtaagc
    22381 gaactcagtg taagaaattc ctgtttcgat ccgtttttta acagattcct tactcatcat
    22441 gtagttgacc gtgaagtatt ttccaatgtc acggaggaag tcaatgaagc tgatgctgcc
    22501 aaaccagtcg tagttgttga ccatgacagc cttgttttcg ccattttcaa agtcaagaaa
    22561 acgagaaagt tgtccttgga tagacttgac ccagccatct actgtgtctt ttgtttggag
    22621 actacgttca gcatctttga aggacggatc tccgatgaga cctgtagcac cgccaacgag
    22681 cgcataaggt ttgtgacctg ctagttgcaa gcgacgactt gtcaagattg cgacaaggtg
    22741 gcctaggtga aggctgtcag cagttggatc gtagccagta taataagaaa cttgaccttc
    22801 ttctagggct ttacgcaaag cttcttcatc agtcgtttga aatatcaaac cacgctcttt
    22861 tagctcatca aaaatgtgca tgtgtctttt ctccttttta aaattattgt ttctacctat
    22921 tgtatcacaa acttgggcaa tagcctagca gaatagggaa gaaagtggct attttattga
    22981 aaatttccct tttgtggtat aatagataga gtgaggaaat ccatgcaaaa tcaattaaat
    23041 gaattaaaac gaaaaatgct ggaatttttc cagcaaaaac aaaaaaataa aaaatcagct
    23101 agacctggca agaaaggttc aagtaccaaa aaatctaaaa ccttagataa gtcagccatt
    23161 ttcccagcta ttttactgag tataaaagcc ttatttaact tactctttgt actcggtttt
    23221 ctaggaggaa tgttgggagt tgggattgct ttggggtacg gagtggcctt atttgacaag
    23281 gttcgggtgc ctcagacaga agaattggtg aatcaggtca aggacatctc ttctatttca
    23341 gagattacct attcggacgg gacggtgatt gcttccatag agagtgattt gttgcgcact
    23401 tctatctcat ctgagcaaat ttcggaaaat ctgaagaagg ctatcattgc gacagaagat
    23461 gaacacttta aagaacataa gggtgtagta cccaaggcgg tgattcgtgc gaccttgggg
    23521 aaatttgtag gtttgggttc ctctagtggg ggttcaacct tgacccagca actaattaaa
    23581 cagcaggttg ttggggatgc gccgaccttg gctcgtaagg cggcagagat tgtggatgct
    23641 cttgccttgg aacgcgccat gaataaagat gagattttaa cgacctatct caatgtggct
    23701 ccctttggcc gaaataataa gggacagaat attgcagggg ctcggcaagc agctgaggga
    23761 attttcggtg tagatgccag tcagttgact gttcctcaag cagcattttt agcaggactc
    23821 ccacagagtc ccattactta ctctccttat gaaaatactg gggagttgaa gagtgatgaa
    23881 gacctagaaa ttggcttaag acgggctaag gcagttcttt acagtatgta tcgtacaggt
    23941 gcattaagca aagacgagta ttctcagtac aaggattatg accttaaaca ggacttttta
    24001 ccatcgggca cggttacagg aatttcacga gactatttat actttacaac tttggcagaa
    24061 gctcaagaac gtatgtatga ctatctagct cagagagaca atgtctccgc taaggagttg
    24121 aaaaatgagg caactcagaa gttttatcga gatttggcag ccaaggaaat tgaaaatggt
    24181 ggttataaga ttactactac catagatcag aaaattcatt ctgccatgca aagtgcggtt
    24241 gctgattatg gctatctttt agacgatgga acaggtcgtg tagaagtagg gaatgtcttg
    24301 atggacaacc aaacaggtgc tattctaggc tttgtaggtg gtcgtaatta tcaagaaaat
    24361 caaaataatc atgcctttga taccaaacgt tcgccagctt ctactaccaa gcccttgctg
    24421 gcctacggta ttgctattga ccagggcttg atgggaagtg aaacgattct atctaactat
    24481 ccaacaaact ttgctaatgg caatccgatt atgtatgcta atagcaaggg aacaggaatg
    24541 atgaccttgg gagaagctct gaactattca tggaatatcc ctgcttactg gacctatcgt
    24601 atgctccgtg aaaagggtgt tgatgtcaag ggttatatgg aaaagatggg ttacgagatt
    24661 cctgagtacg gtattgagag cttgccaatg ggtggtggta ttgaagtcac agttgcccag
    24721 cataccaatg gctatcagac cttagctaat aatggagttt atcatcagaa gcatgtgatt
    24781 tcaaagattg aagcagcaga tggtagagtg gtgtatgagt atcaggataa accggttcaa
    24841 gtctattcaa aagctactgc gacgattatg cagggattgc tacgagaagt tctatcctct
    24901 cgtgtgacaa caaccttcaa gtctaacctg acttctttaa atcctactct ggctaatgca
    24961 gattggattg ggaagactgg tacaaccaac caagacgaaa atatgtggct catgctttcg
    25021 acacctagat taaccctagg tggctggatt gggcatgatg ataatcattc attgtcacgt
    25081 agagcaggtt attctaataa ctctaattac atggctcatc tggtaaatgc gattcagcaa
    25141 gcttccccaa gcatttgggg gaacgagcgc tttgctttag atcctagtgt agtgaaatcg
    25201 gaagtcttga aatcaacagg tcaaaaacca gggaaggttt ctgttgaagg aaaagaagta
    25261 gaggtcacag gttcgactgt taccagctat tgggctaata agtcaggagc gccagcgaca
    25321 agttatcgct ttgctattgg cggaagtgat gcggattatc agaatgcttg gtctagtatt
    25381 gtggggagtc taccaactcc atccagctcc agcagttcaa gtagtagttc tagcgatagc
    25441 agtaactcaa gtactacacg accttcttct tcaagggcga gacgataatt ctctaaatga
    25501 agtggccaat caatggattg ccactttttt cctttcgtgt tacaataagg gtatgaatca
    25561 gtatcagaaa aagattgtta acggaaaaat ttattcgctc ctatccggct taatatgggg
    25621 aatctgtgga attttaggag agtacttctt tactcattat caggtgtctt cgggctggat
    25681 tacctctatg cgtttgacac tggcagggag tcttgtactc atttggtctg caatacaatt
    25741 aaaatcgcaa gtgctagata tttggcgaga caagaaaaat tacctgccct ttttagccta
    25801 tgctattttg gggatttttt cagttcagta ttttttctat ctctgtgtag aatactcaaa
    25861 tgctacgaca gcaactattt tacagtttat tagccctgtt tttatcctct tttacaatcg
    25921 cttggtttat caaaaacgag cgtcaaaaag cgctgttttc tatgttttgg ttgccatgct
    25981 gggtgtttgc ttgatggcga caaagggaga tctctctcag ttatccatga cgccgctagc
    26041 tcttataaca ggtttgctga gtgccatggg tgttatgttt aatgttatct tgccccaacc
    26101 ttttgctaag cgttatggtt ttgttcctac ggttgggtgg gggatgattt tggcaggttt
    26161 gtttagcaat gtcctctcgc cggtttatca gctttccttt actcttgata tttggagtat
    26221 cttgatttgc ctcattatcg ctttctttgg aacggctttt gcttttttca tttccatgaa
    26281 ggctgtgtcc ttggtttctc ctttggtggt tgccgttatc agtgccagtg aacctctctc
    26341 ttctgctctc ttgagtgttt tgttcttagg attagtagtg gattggtccc tccttctagc
    26401 tatagccttg attattttac ccatgatatt tttgtctata gaagaagcga aagaaagtag
    26461 ataaaaagtc ttttcttaat tctaaaagtg tgctatacta gaatagtcaa taaaacacgg
    26521 ggagatagtt gtgaagagtg tttttaggtt gtatcggtag gggcttgctt ttaccgacag
    26581 cacgttttat ctcacatccc taaaaaatca tacctaaaaa cagacaaaaa ggtttcaaat
    26641 ttgaggcctt ttttggtaga ataggtatca ttataacgaa ccaggaggca cctatgactg
    26701 ctacaaaaat gaacgctcaa gaaattatcc aatttatcgc caatgctgaa aagaaaacca
    26761 gtgtcaaagt aacctttgag gggcaactcg caactgctgt gcctagctct gttgtcaaac
    26821 taggaaatgt cctattcgga gactggaagg acgtggctcc gcttcttgaa ggtttggtag
    26881 aaaatcaaga ttatgttgtc gagcaagatg ctcgtaattc tgcagttcct ttgctagata
    26941 agcgtgctat caacgctcgt atcgagccag gtgctattat ccgtgaccag gtggaaattg
    27001 gtgacaatgc tgttatcatg atgggagctg ttatcaatat cggtgctgaa atcggtgctg
    27061 gaaccatgat tgacatgggt gccatccttg gtggccgtgc tatcgttgga aaaaatagcc
    27121 acgttggtgc aggtgcagtt ttggcaggtg tgattgagcc agctagtgct gaaccagtcc
    27181 gtgtcggaga caatgttctt atcggtgcta atgcagtggt tatcgaagga gtccaaatcg
    27241 gtagtggttc agttgtcgct gcaggagcta tcgttaccca agatgtccca gaaaacgtgg
    27301 tagtagcagg tgttccagct cgtatcatca aagaaattga tgcccaaacc caacaaaaaa
    27361 cagcgctaga ggatgcgctt cgtaccttgt aattgtaaaa gtaaaaaaga ggcggaaccc
    27421 tttttccagc ctctttctgc tataacggag gacagataga tgttagattt gattcagact
    27481 agacgagctt tacaccagat tccagagatt ggcttggagg agttcaagac tcaggcttat
    27541 ttgctggatg tgattgagaa attgactacg ggcaaggatt ttgttcaaat tcgtacttgg
    27601 cggacaggga ttttggtcta cctgcaggga agtcagccgg agcgaaccat tggttggcgg
    27661 acagatattg atggtctgcc tatcgtcgaa caaacaggtc taccttttgc ttctcaacac
    27721 caaggtcgca tgcatgcctg tggccatgat tttcatatga ccattgcctt aggctgtctt
    27781 gagcgcgccc ttgaggagca acccaagaat aatctgctct ttctatttca gcctgctgaa
    27841 gaaaatgaag ctggtggcat gctcatgtat gaggacggtg cttttggaga ttggttgcca
    27901 aaccaattct atggtctcca tgttcgtcca gatttgaaag tcggccagat tgcgactaat
    27961 actcatacac tctttgcagg aacttgcgag gtgaagatcc gtttcaaagg caaaggtggc
    28021 cacgcagctt ttcctcatga agccaatgac gccttggtgg cggctagtta ctttgtgacc
    28081 caagtgcagt cagttgttag ccgcaatgtc aacccaatcg agggagcagt ggtgaccttc
    28141 ggcgtttttc aagctggaac caccaacaat gtcatcacag acacagcttt tttacatgga
    28201 actattcgtg ccttgacaca ggacatgagt ctcttggtgc aaaagagggt aaaaacagtt
    28261 gcagaagggg ttgcagctgc ctttgatatg gaagtcgaag tggaactcaa acaaggtgga
    28321 tacctacctg ttgagaacaa tccagccttg gcgcgtgaac tgatggactt ctttgacgaa
    28381 aaagacggaa tcgagttgat tgatatcgaa cctgctatga caggcgagga ctttggttat
    28441 ctcctttcaa aggttgatgg cgtgatgttt tggctaggta tcgatagtcc ctacgctctt
    28501 catcaccctc aaatgagtcc taaggaagaa gtcttagcta ttggggtggc tgcggtgtct
    28561 agtttcctga aaaagaaggc agcagaatag agggcttgtc tatgaaatcg gaattacgca
    28621 agcaagtctt gcatgaaatg aaggctatat ctcaagagca aaaacaggct atagaccaag
    28681 ctttaaccga gcggctttta caccatccct tctaccaaga agccaaggtc atcgcaacct
    28741 acctctcttt ttctcatgag tttcaaacgc gggaactgat tgagcaggcg ctgaaggacg
    28801 gcaagaaggt tttaataccc aaaacttatc ccaaggggcg catggagttt gtggtctatg
    28861 atccgcaaca gttggtaaaa acttcctttg ccttactgga gccacaggga gatgtggaag
    28921 tggtggatgc atctcagatt gatttgattc atgttcctgg tctggctttt acgacgaaag
    28981 gatatcggat aggatacggt ggaggctatt atgaccgcta tctggaacat ttttctggtc
    29041 gtactttgag tacgatatat ccttgtcaaa ttcaggactt tatacctgaa aaccatgata
    29101 ttcctgttca ggaggtatta attgatgaag gaaatctttg atagacgtta ccctgtgacg
    29161 agtttcttcc tcttagtgac ggccttggta tttttactaa tgttggtcac tgcaggcgga
    29221 aactttgaca gggcagatac attatttcga tttggagcca tgtatgggcc agctattcgc
    29281 ctctttcccg agcaggtttg gcgtctcttg tctgccattt ttgttcatat tgggtgggaa
    29341 catttcattg ttaatatgct ttcactttat tatcttggaa ggcaggtaga ggagattttc
    29401 ggttctaagc agtttttctt tctctatctt ttatcaggaa tgatgggcaa tctctttgtt
    29461 tttgtattta gtcctaaatc cttagcagca ggcgcttcta cctctcttta tgggctattt
    29521 gccgcgatta ttgttcttcg ctatgcaact cgcaatcctt atattcaaca gctagggcaa
    29581 tcctatctga cactttttgt ggttaacatt attggaagtg ttctgattcc aggaatcagc
    29641 ctagcaggcc atatcggtgg tgcagttggt ggcgcatttc tagcagttat ctttccagtt
    29701 agaggagaaa aacggatgta taataccagc cagagattag gagcggtagt cttgttcgta
    29761 ggactcgcca ttttgctttt ctacaaggga atgggaatgt gacgaagttg aaagaaaatt
    29821 tgtgtaatga aaaaagataa ggcatttttt gaaccttatc tttttatttt attttattcc
    29881 ttctcagtca attcttttcc aagttggatg aggtaattct tcaaatcatc tttgacttgt
    29941 gggtgtttga gggcgtagtc gatggatgtt ttcatgaagc caaacttgtc tccgacatcg
    30001 taacgagccc cattgaactc acgagcaaat acacgttgtg ttttattgag ggtgtcgatt
    30061 gcatctgtca gctgaatttc atttcctgca cctggagctt ggttttcgag gatttggaaa
    30121 atttcaggcg tgaggaggta gcgtccgata atagcaaggt cgctaggagc gtcctctgga
    30181 gctggttttt caacaaaggt ttcaacactg taaagaccat cttttccttc gccttgcgga
    30241 gcaataaccc cgtaagcaga tacttcgtca tgagggactg gcatgacagc gatagtagac
    30301 gcgtgggtac gctcgtagtc atccatgagt tgtttggtaa gtggaacagc cttttcgtct
    30361 gtgatatcca tcaagtcatc accaagcata acgacaaaag gttcatttcc gacgaaagcc
    30421 ttagcttgca aaacagcatc tccgagaccg cgtggatgag tttggcggat aaaatgcaga
    30481 cgcatgtcag ttgttttatc aactagcttc aaaagatctg ttttcccttt ttctttgagg
    30541 ttatattcca attcgaagtt tgaatcaaag tggtcctcaa tagaacgttt tgatttacca
    30601 gtgacaacta gaatatcttc aatacctgat ttgagagctt cttccacgat aaactggata
    30661 gttggtttgt ctacgattgg caacatttct ttggcaaggg ccttggttgc tggtaaaaat
    30721 cgagttccta gtccagcagc agggatgact gcctttctaa cttttgatgt cataaaaatc
    30781 ctttctatag agggttaaga ccactcattt tctgctttaa attcattgtt catgatgtca
    30841 taaatggcat ctttgatatt ggttccgtga taaataactt ggtaaatagc ctgtgtaatg
    30901 ggcatataga ctccaagttc ttgggctagt tcataggctg ctcgagtcgt tgaaattcct
    30961 tcgattacca tgcccatatt agcttctata tcagctaggg attctcctcg tccgagagca
    31021 tctccagctc tccagttacg agagtggatg gaagttcccg ttacgatcaa atctcccaca
    31081 ccagataagc cgctataggt caatggactg gccccgagtg ctacccctag gcgggtgatt
    31141 tctgctaaac ctcgagcgat gatggctgcc ttagcattat caccaaatcc aagaccatgt
    31201 aaagctccag caccgacagc aataatattt ttaagagcac cagcagtttc aaccccgata
    31261 acatccgtat tggtataaag tcggaagtag tgattactaa atagcttctg aacgtattga
    31321 gctgtttgta aatctttaga agcagcagtt attaaagtta ggtcacgcac aatggtctct
    31381 tctgcatgac taggccctga aacaacgacg atatcactac ggagatgttc aggaatttct
    31441 tcttcaagaa tggttgataa tcgtttatgg ctatcaggtt ctaatccctt tgatgcgtgc
    31501 atgatgataa ccttatggtc caaggtttgt gcaacttgct gggcaacaag tcgtgtcact
    31561 tttgttggga caacaaacaa aatcgcatcc acatctttca atgtttctgc taagtcggtg
    31621 taggcaatga tattttcgtc tagaacgaca tctttaaagt agtgcttatt agtatggtgt
    31681 gtattaattt cattgatttg ctcgggaaga tttccccaaa tacgtacctc gtgtccattg
    31741 tcatttaaga cttgtgaaag ggcggttccc caagaaccag gccccaagac ggcgacggtt
    31801 tgtttttcca tgatttcctc cttgatagag ttctttctct tattctatca tattctaggg
    31861 gattttgcac ttgcattact ggggtatggt ggaaaaatac acaaaaaccg agacgaaggg
    31921 ataaactctt agtctttagt taaagtgaga agaaatctga tagatagttt gattcagtat
    31981 atgcttataa tagaggtaaa caactcagga agttcttgta ggttgcgaga gtttggctaa
    32041 aaaaatcagt cgttcagaat tttgtggtga tgagtctgaa ttaagtatcc gtcaattaat
    32101 tagaattgaa aatggagaat ccagaccaac actaacaaag ttaaaatata tcgctgaacg
    32161 tttgggggtt gaagattaca agttgatgcc aagttatata gagttggata aggaatacct
    32221 agaattgaag tatttcttga tgaggactcc tacatacgaa gatgaaacta tcgcccaaaa
    32281 gaaagagagt gttttgataa gatttttgaa gagtattatg ataggctacc tgaggaagaa
    32341 agatttatca tcccaaatta ttcatatctg gcactaacga actacacagt tcaaaaatta
    32401 ccagaaaagc tagttgaaat actgtccttc tggtgatttt gcttaatttc tgatgttcga
    32461 gacataattg aggagatttg tcttgatttt ttcctaaaaa agggcagact cctcccttgg
    32521 tttgatgctc gatttttaaa ataaggtgac ttattctgtt aggcatgttt tcccctgccc
    32581 tctagctcta tatggaacag ggagtatcag atttatctgg cagattgtat caaataaggc
    32641 ttgaaactgt tttgaatagg catatagact tgagaatttg agaatatgtc gtctagcagt
    32701 agagacatat tttccggcaa tatgaaggaa gagacgtcga aaacgcttga tagtcaaggc
    32761 ctttacttca tcaccagcta gctgctttaa aaagaggtag agattataag ccagacagcc
    32821 catcatcata cgtacttcat tcttaatcat ggtcgaacta tctgtcttat ccccaaagaa
    32881 tcctgctttc ctttctttga taaagttttc agcattccct cgttcacgat agaattgaaa
    32941 cagctcctca ctatctacac tgcttaaatt gttcaaatga acttttttac aaccataaaa
    33001 aagagcactt aatcgtactc ttctctttta aggattagtt gaattaattc aaatccacca
    33061 gttctcctgt ttctaggtag actaggcgtt cacaaatgtt agcaatgtaa tcagcgaagc
    33121 gttccagatg ccctatgata taaaggtatt gagttccatt gggaattgag gtttcttggt
    33181 ctttcataag tccaatgatt tcctttgata aggcataata atattggtca atctgttcat
    33241 ctttttgagc aatactaata gcttttgagg cttggtgcaa aggaaaggca accaataaat
    33301 cggctagcat gctgagggat aatttaccca tttggtgtaa ctgttcttcg tcaggggcta
    33361 gttgattttc ttttagttgc aaaacagctt tagcaatgcc tgccatatgg tctcccatac
    33421 gttcaaggtc tgaacaagaa gacatgatgc taatcacaaa tcgaaggtca gacacttgtg
    33481 gctgctgcaa ggccaacaaa cgggcacagg tcaattcgat agcgctttga ccttggttga
    33541 tagcatgatc cttattgata attagctctg ccatctcctt gtctttggag gctaaggcca
    33601 gtaaggcttt tgaagctgtt tcaaggacaa gttgccctag tcctaaaaag gattgttcta
    33661 attcatgcaa ttctaagtca aattgatttc tcataggttt ttccttcctt atccgaaccg
    33721 tcctgaaata tagtcttctg tgcgctgatc ttttggattg gtaaacacgt caacggtatc
    33781 tccaaattcg caaatttctc ctgttaagaa aaaagcagtt ttatctgaaa tacgtgaagc
    33841 ttgttgcatg ttatgggtaa caatgataat cgtataatcc ttttttagtt gctgaatgag
    33901 gtcttcaatt tttaaagtgg agatagggtc taaggctgaa gtcggctcat ccattaacag
    33961 aatatcaggt tctactgcta aagctcgcgc aatgcaaagg cgttgctgct gaccgccaga
    34021 taaggacatg gcactctttt taagatcatc tttgacttct tcccaaatgg ctgccccttt
    34081 taaagatttc tccactaagg catctaattg ttttttgtct cgaataccat gtgtccttgg
    34141 gccataagcc acgttatcat agatagacat ggcaaaggga ttaggctgtt gaaaaaccat
    34201 ccctacacgc ttacgtagct gattaaggtt gaatttgcta ctataaatat cttgctcatc
    34261 taagaggact tggccttcaa tatggcaaga aggaaccaaa tcgttcatcc ggttaagggt
    34321 ttttagaaaa gttgatttgc cacaaccaga tgggcctatc aaggcagtaa tctgtctttc
    34381 tggtaattga atcgaaatat tttttaaggc ttgaaaatcc ccgtaaaata agtctaggtg
    34441 tctgactgaa aatgttccca tactaggaag ctcctttcac aagttttcga gataataagc
    34501 ttgatagagt atttatcatt aaaacagtaa taatcaaaat cacaccggta gcataggctt
    34561 cattgacatg tagcccctca cttgacagca tatacatatg cagggctaga gaacgacctg
    34621 aagacatgag actacttggc gtattggtag aggtacctaa tgtatacatg agggcagctg
    34681 tttcaccaac gatacggcca atagctagta tcactccagc taaaatacct ggcatggcaa
    34741 ctggtagaac aattctaaaa acagtccgta acttacctgc cccaagtcca taacttgctt
    34801 gacgcatgct atcactaaca gataaaaggg cttcttctgt tgagcgaata atgactggca
    34861 acaccatgat aactgaggtt aagattcctg ataacagaga gtattgaaaa cctaagaaga
    34921 ctacaaagaa gagcatgcca aacagaccaa aaacaatgga aggaatccca gacaaggtat
    34981 ctgaggccaa tcgcatgatt ttaacacaaa gggaatcttt ttttgtatat tccacaagat
    35041 aaaaaccagc aaaaatccct atgggcaagg ctaaaagaag agcaccaaag accagaataa
    35101 cggtggaaat aatcgctggc ataagggaaa tgttctcaga agtataagtc caagaaaaga
    35161 gggatagact tagatgaggt aagcctttga tgaggataaa accaatgatt aaaaagagag
    35221 agccaaaggt taaagctgaa aaacaataaa cgagaagttt tagcaggtat ttactcataa
    35281 gatgattttc ctttcaagta ggcaaagtag gcattaatca agagaataag gaaaaagaga
    35341 actgctgagg ttgcaataag ggcttcccta tgctgacctg atgcgtaagc catctccaga
    35401 acaatattgg ttgttaaggt tctggttcct gaaaagagtc cacttggaat aattggctgg
    35461 ttgcctgcca ccaaaataac tgccatggtt tcacctactg cgcgaccgat tcctaaaata
    35521 actgctgata aaataccaga tctcgcagct ggcaagatga cactaaaaat actccgttca
    35581 tgactagctc ctagagccaa gctaccagaa taatacgttt tgggaactgt tcggatagca
    35641 gattctgaca aactgataat ggttggcaaa atcattattc ctaatagtaa cgaagcggtt
    35701 aggacactca tgccatttcc taaaaagctt ctaatccaag gcaccaataa ttgtaggccg
    35761 aaaaaaccat aaacaataga tggaatggct gccatcaagt tgatagctga ttttaagaag
    35821 ccatagacgg gctttggaca ataataaacc ataaacaccg atgtcaagat gcctgttggc
    35881 accccaatca caatcgctcc taaggtaatt aataaggaac caacgatcat tggtaaaata
    35941 ccatagcttg ccggaatgtt cgttggcgac caatcactgc ctaataaaaa acgggcaaag
    36001 ccgtagttag ctatgaaagg taagccatta ctaaaaataa agaaacagat tagcaaaata
    36061 gctacaacag ctactgttgc actcatgaaa aaaattgccc taaaaactgc ttctttgaag
    36121 gcttgttttg tcacatcttg tcctttctag tgaagaaagt aagggagata cgacacctcc
    36181 ctacttgcct tctttatctt attgtacgat gaaacgtctg catctcttta gagatttatg
    36241 gagcaaacat tttatttaat cttgtcccag gtggttaatt tgccactaaa aacgtctgca
    36301 agttcagcca tactgacttg gcttgcctta ttgtcattat tgaccacaac agcaataccg
    36361 tctaaagcaa tagcatcatg ggtgagactc ttaccttctt caggagttaa ttccctagaa
    36421 accataccaa tatcagcggt tttctcctta acagcggtaa tacctgctga agacccatta
    36481 gaggtaatat caatcgtaac ttctggattt tcttttttat aagcttctgc taatttttcc
    36541 attaaagaag atactgaagt ggaacctaca acagacaact tgcctgataa gtgttggctt
    36601 gtatattctg tggtttcggt tttagcttca ataaatttat tatctgtgac cacttgttga
    36661 ccttgtttgg agtggataaa gctgataaaa tcttgaccta gcttggaaag attagaagac
    36721 caaacaatgt tgaagggacg ttgaagaggg tatttaccat ctaaaactgt gtctcgacta
    36781 gccttgacac catcaatctc taaagctttg acagatttcg ttaaagatcc caaggagatg
    36841 tagccgatag cattagcatt cccttgaact gctgagagaa caccttctgt actattttga
    36901 atcacagctg ttttggcagt gttgtcaatt tttttatcac cgtctttttt gagaatccct
    36961 gtgatttctg tgaaggcacc ccgtgttcca gagccatttt ctcgtgaaat cacctcaatc
    37021 gttcctgaag ctgactgttt ggaagcagct gactgattgc cacaggcaac aagcccaaat
    37081 cctgataagc caatggctgc aagagtaagc atttttttga atttcataat aatcaccttt
    37141 atctctatgt atttttcttg tgtaggctta ctacatttat agtctaacaa gtctttgtaa
    37201 aggtttatcc ctgattcatg taaagattgt gtaaagaatc aaaaaaagcc acttttgaaa
    37261 aatggctgct cctaaaaata gctttaaaaa ttattagtcc tgtgcgaaag attggttagg
    37321 aagaaaaatc gtgaagcaac tgcctctgcc aagctgactc gtcaccgtga cttggccacc
    37381 taataattga ctgagttctt tgacaatggc aaggccaaga ccagtgccac cagtttgtct
    37441 gcttcgacct ttattaactc ggtaaaaacg ttcaaaaata cgatcctgct ctaattgact
    37501 aataccaatc cctgtatctg atacagaaat cttaatgcct tcgttcacct tttgggtctt
    37561 gacctcaatt tttccccctt gttcagtgta acggatggca ttggataaaa gattgagtaa
    37621 gatttgggaa agtaattgac tatctgatac gagggtgaca tcatctggca cctgcacctt
    37681 tagctgtaaa tccttcttct tgagctgagg ttgcaagctt tgagtcaaat cctgtacaaa
    37741 ttctgccaaa gaaagggtcg tccattgtat aggcatttgt tgagccttag ataaggtaag
    37801 aagatgctca acaatatgct caagacgcaa gctttctttg taaataatgt ctagaaagtc
    37861 atccttgagc gcttcttctt cagctgacat ccccttaatg gtttcagcaa agcccttaat
    37921 cgaagtaact ggtgtcctca attcatggga ggcatttgag acaaaggcta aatttaactt
    37981 ttcataagtt ctaatcgttg ttaaatcata tagcaagacg agcacagctt ccacagattg
    38041 ggtggggcta aaaacgggaa ctgctgtcac ttctaaaatc aagtcaccct catgaaaccc
    38101 acttacttct tgttttaacc ttgttttttg atcaaaggct tggtgaacta aatttcgaat
    38161 atccatccgt ttgaggtcat caagtgaact tatgtcgccg tccacatcgg gaaaataatg
    38221 aggcagagag cgactggata ataacatctg accttgagcg gaaactaaaa acgtccccat
    38281 ggttaggtgc gacagaagaa cctccattgt ttcggctagg tccttgtatt gctgatcctg
    38341 ttgggagact ttggttttta gggcagacac atactgagcc aaagacttta agtcttcttg
    38401 ccctttttct aaaaagtatt cactactggt caagagaggt tggtgcaagg tctcaaaagc
    38461 aacttcccat ttccaaaggc aaaagagcca gtagccacct tgtcccaaag aaagggctag
    38521 aagaaagaga ccgatgcctt tactgatcca agttaatacc atccctgcaa tcagaatgag
    38581 gctaacactt agattgacta gccaaaattg aaggtagcgt ttcatctata actccttgaa
    38641 cttataacca taaccccgaa tggttcgaat aaattgaggg gctttaggat tgtcttcaat
    38701 tttttccctc aacttaccaa tatgaacgtc caccaaacgt gtttcctgcc caaagtcata
    38761 cccccagata cgttccaaaa gacgctctct agtcagtgtc atgttgggat gtttcataag
    38821 atagagcaag agttcaaatt cttttggggt caaactcagt aacttattcg ccttgtagac
    38881 ttcatgacgc tcagggtata ctttcaaggt cccaaatagc caagaatcgt cagcgatatt
    38941 atctgaatca tctccttctt gttctccttt agttcgcctg aggacagcct tgacacgcgc
    39001 cagcaattct ctagggctaa aaggtttggt caggtagtca tcagccccta attccaaggc
    39061 caaaacctta tcaaattcat cacttttcgc agaaaccatc ataattggag ttttgacgcc
    39121 tttggctctc agccgcttac aaacttccat gccatctaat tgtggtaaca tgatatcaag
    39181 caagataaaa tcaaagggtt ctgtttctgc caaagctaag gccttccgtc catttgttac
    39241 caattgagta gaaaagcctt ccttacttaa atggtagtca agcaatttca gaatgtgttc
    39301 ttcatcatcc actaataaga cttgttttgt catctattat ctcctattgg taacattata
    39361 acacaattat cagaaatcct aacattgcta aatcagatta aatttgctta tcaagactag
    39421 tatctggtca aacgctcaat catctccttg tgctctggat aggtcgccag tagatctacc
    39481 ctttcaaata attcaaaatc ctcaaattca aaaccaggag caacaagaca agaaaccaga
    39541 gcatcatcct tatcaactgt tgatccccaa atagtgccct taggaacaca gtagtgaagt
    39601 tgttgccctt tggatatgtc caggcctaaa gtgactgctt cgtagtgacc atctgctgta
    39661 atcatgtgaa cagtaagtgg ggattctgca tgaaaatacc agatttcatc tgctgtcaat
    39721 cggtgaaaat gtgaaggatt cgtttcttct taataagaaa taaatactgg tataaagcgc
    39781 ccttccctta ccagcaaggt ttatagtgtc tgaagctttt tttgtttgtc taaaatagcc
    39841 accttcaaca tggggagcta actctagagt tcttatcaag tcttctttat ccgtcggagc
    39901 caatgggttg aagtaactct tgttcaaagt ggtgttacga tttcaagaac tcctctcagt
    39961 tctgaggaca cggtaatgat tgatgcgacg gaagtacaaa tcaatcgccc taaaaaaaga
    40021 attagcgaat cattctggta aaaagaaatt tcacgctatg aaggctcaag cgattgtcac
    40081 aagtcaaggg agaattgttt ctttggatat cgctgtgaac tatagtcatg atatgaagtt
    40141 gttcaaaatg agtcgcagaa atatcggaca agctggtaaa atcttggctg acagtggtta
    40201 tcaagggctc atgaagatat atcctcaagc acaaattcca cgtaaatcca gcaaactcaa
    40261 gccgctaaca gttgaagata aagcctgtaa ccatgcgcta tctaaggaga gaagcaaggt
    40321 tgagaacatc tttgccaaag taaaaacgtt taaaatgttt tcaacaacct atcgaaatca
    40381 tcgtaaacgc ttcggattac gaatgaattt gattgctggt attatcaatc atgaactagg
    40441 attctagttt tgcaggaagt ctattatttg gttaggtgaa ttagtgaagc gtttaggcaa
    40501 gtgtctctgg ttacgacgtc atggcctcta aatcgattat atttaggggt catgactagt
    40561 gaagcagtta gctagttcgc atataagcgg ctagcgtcta acaattagga actttagttc
    40621 caataacttt aagattacga cgttttagga cataaatcga tcatatttat gtcctaaaac
    40681 tagtgaagcg cctagccaaa gtccgaatag gatttggcgt tagttactta gattgctttg
    40741 caatcaagta actttggcga tttacatctt ctctggtgct tctactccaa gcaagcgaag
    40801 ggcttctttg agaacgactg cggttgcgta gctgagggct agacggctgt cgcgttctgg
    40861 gctttcatcc aagatacgtg tatgtgcata gtatttgtta aaggattgag ccaggctaat
    40921 tgcaaattta gcaatgatag aaggttcaaa gttatctgcc gcacggttga taatacgtgg
    40981 gaagtcttga atgagtttaa tgatttccca gctttcagta tcattcaagc tatagttgcc
    41041 agctgtttct ggtttgaaat cggctttgcg taagatagat tggatacgag cgtaggcata
    41101 ttgaacgtaa ggtccagttt caccctcgaa ggataccata gcttctaggt cgaagtcgta
    41161 tccatttgta cggtcagttt tgaggtcata gaatttaatg gctccaaccc caacagcatg
    41221 tgctacttgg tctttgtttt ctagttcagg atttttagcc tcgatttgga ccttggcacg
    41281 gctaacagcc tctgcaacag taggctctag caagatgaca ttccctttac gagtagagag
    41341 cttcttccct tcttttgtaa ccagaccaaa aggaacgtgg gtaatgtcgt cactccaatc
    41401 gtagcccatc tcttgcaaga cagctttgag ttgtttaaag tgggcagatt gctcttgacc
    41461 aacgacgtag atagatttag caaattggta ttcattttta cggtagaggg ctgcagccaa
    41521 gtcacgtgtg atatagagag ttgcaccatc agacttcttg atgagggctg gatgttcaat
    41581 tccatatttc tcaagattca caacttgggc accttctgat tcaagaagta gtcctttttc
    41641 agaaagaatg tctacaactg catccatctt atcattgtag aaggcttctc cgttatagct
    41701 gtcaaattca accttcaatt cattgtaaag gcggttaaat tccactaaac tttcatcgcg
    41761 gaaccattgc caaagagcga gagcttcctc atctccattt tcaagtttac ggaaccattc
    41821 gcgcgcttct tcatccaagc tagggtcatt ttcagcttca gcgttgatgc ggacatagag
    41881 tttaaggagt tcatcgattg gatgagcttt tacagcttct tcgtcgcccc attttttata
    41941 ggcaacaatc aacatcccaa attgtttacc ccagtctccc aaatggttga ccttgaccgt
    42001 ttgataaccg attttttgga aaatatgtga caagctatct ccgataacag ttgaacgcag
    42061 gtggccaata gaaaatggtt tagcgatatt cggactagac atgtcgataa caacattttc
    42121 ttgtttacca atattttggt cagcatagtg ttctttttca gtggtaacag cttgcaatac
    42181 ttgagcagaa atggcagatt tatcaaggaa aaagttaacg taaggtcctg ttgcgacaac
    42241 tttttcaaag gcttggctgt tcattttttc agccagttca gccgcaatca tttgtggtgc
    42301 tttacgttcg acttttgcaa gagaaaaagc agggaaagca atgtctccca tttctgagtt
    42361 tttaggggtt tccagtaact ttaaaacagc ctcttggtcc aggctatcaa tgatgctaga
    42421 taattcgcta gcaatcaatt cttttgtatt cattaagagc tcctttttgg acttttctac
    42481 tattttatca caattttaaa gaaagaagaa aaaatttttg aaatctcctg tttttttggt
    42541 ataatatggt tataaatata gttataaata tgcacgcaag aggattttat gagaaaaaga
    42601 gatcgtcatc agttaataaa aaaaatgatt actgaggaga aattaagtac acaaaaagaa
    42661 attcaagatc ggttggaggc gcacaatgtt tgtgtgacgc agacaacctt gtctcgtgat
    42721 ttgcgcgaaa tcggcttgac caaggtcaag aaaaatgata tggtgtatta tgtactagta
    42781 aatgagacag aaaagattga tttggtggaa tttttgtctc atcatttaga aggtgttgca
    42841 agagcagagt ttaccttggt gcttcatacc aaattgggag aagcctctgt tttggcaaat
    42901 attgtagatg taaacaagga tgaatggatt ttaggaacag ttgctggtgc caatacctta
    42961 ttggttattt gtcgagatca gcacgttgcc aaactcatgg aagatcgttt gctagatttg
    43021 atgaaagata agtaaggtct tgggagttgc tctcaagact tatttttgaa aaggagagac
    43081 agaaaatggc gatagaaaag ctatcacccg gcatgcaaca gtatgtggat attaaaaagc
    43141 aatatccaga tgcttttttg ctctttcgga tgggtgattt ttatgaatta ttttatgagg
    43201 atgcggtcaa tgctgcgcag attctggaaa tttccttaac gagtcgcaac aagaatgccg
    43261 acaatccgat ccctatggcg ggtgttccct atcattctgc ccaacagtat atcgatgtct
    43321 tgattgagca gggttataag gtggctatcg cagagcagat ggaagatcct aaacaagcag
    43381 ttggggttgt taaacgagag gttgttcagg tcattacgcc agggacagtg gtcgatagca
    43441 gtaagccgga cagtcagaat aattttttgg tttccataga ctgcgaaggc aatcaatttg
    43501 gcctagctta tatggatttg gtgacgggtg acttttatgt gacaggtctt ttggatttca
    43561 cgctggtttg tggggaaatc cgtaacctca aggctcgaga agtggtgttg ggttatgact
    43621 tgtctgagga agaagaacaa atcctcagcc gccagatgaa tctggtactc tcttatgaaa
    43681 aagaaagctt tgaagacctt catttattgg atttgcgatt ggcaacggtg gagcaaacgg
    43741 catctagtaa gctgctccag tatgttcatc ggactcagat gagggaattg aaccacctca
    43801 aacctgttat ccgctacgaa attaaggatt tcttgcagat ggattatgcg accaaggcta
    43861 gtctggattt ggttgagaat gctcgctcag gtaagaaaca aggcagtctt ttctggcttt
    43921 tggatgaaac caaaacggct atggggatgc gtctcttgcg ttcttggatt catcgcccct
    43981 tgattgataa ggaacgaatc gtccaacgtc aagaagtagt gcaggtcttt ctcgaccatt
    44041 tctttgagcg tagtgacttg acagacagtc tcaagggtgt ttatgacatt gagcgcttgg
    44101 ctagtcgtgt ttcttttggc aaaaccaatc caaaggatct cttgcagttg gcgactacct
    44161 tgtctagtgt gccacggatt cgtgcgattt tagaagggat ggagcaacct actctagcct
    44221 atctcatcgc acaactggat gcaatccctg agttggagag tttgattagc gcagcgattg
    44281 ctcctgaagc tcctcatgtg attacagatg ggggaattat ccggactgga tttgatgaga
    44341 ctttagacaa gtatcgttgc gttctcagag aagggactag ctggattgct gagattgagg
    44401 ctaaggagcg agaaaactct ggtatcagca cgctcaagat tgactacaat aaaaaggatg
    44461 gctactattt tcatgtgacc aattcgcaac taggaaatgt gccagcccac tttttccgca
    44521 aggcgacgct gaaaaactca gaacgctttg gaaccgaaga attagcccgt atcgagggag
    44581 atatgcttga ggcgcgtgag aagtcagcca acctcgaata cgaaatattt atgcgcattc
    44641 gtgaagaggt cggcaagtac atccagcgtt tacaagctct agcccaagga attgcgacgg
    44701 ttgatgtctt acagagtctg gcggttgtgg ctgaaaccca gcatttgatt cgacctgagt
    44761 ttggtgacga ttcacaaatt gatatccgga aagggcgcca tgctgtcgtt gaaaaggtta
    44821 tgggggctca gacctatatt ccaaatacga ttcagatggc agaagatacc agtattcaac
    44881 tggttacagg gccaaacatg agtgggaagt ctacctatat gcgtcagtta gccatgacgg
    44941 cggttatggc ccagctgggt tcctatgttc ctgctgaaag cgcccattta ccgatttttg
    45001 atgcgatttt tacccgtatc ggagcagcag atgacttggt ttcgggtcag tcaaccttta
    45061 tggtggagat gatggaggcc aataatgcca tttcgcatgc gaccaagaac tctctcattc
    45121 tctttgatga attgggacgt ggaactgcaa cttatgacgg gatggctctt gctcagtcca
    45181 tcatcgaata tatccatgag cacatcggag ctaagaccct ctttgcgacc cactaccatg
    45241 agttgactag tctggagtct agtttacaac acttggtcaa tgtccacgtg gcaactttgg
    45301 agcaggatgg gcaggtcacc ttccttcaca agattgaacc gggaccagct gataaatcct
    45361 acggtatcca tgttgccaag attgctggct tgccagcaga ccttttagca agggcggata
    45421 agattttgac tcagctagag aatcaaggaa cagagagtcc tcctcccatg agacaaacta
    45481 gtgctgtcac tgaacagatt tcactctttg atagggcaga agagcatcct atcctagcag
    45541 aattagctaa actggatgtg tataatatga cacctatgca ggttatgaat gtcttagtag
    45601 agttaaaaca gaaactataa aaccaagact cactagttaa tctagctgta tcaaggagac
    45661 ttctttgaca attctccact tttttgctag aataacatca cacaaacaga atgaaaagga
    45721 gctgacgcat tgtcgctccc ttttgtctat tttttaagga gaaagtatgc tgattcagaa
    45781 aataaaaacc tacaagtggc aggccttggc ttcgctcctg atgacaggct tgatggttgc
    45841 tagttcactt ctgcaaccgc gttatctgca ggaagtatta gacgccctcc ttactgggaa
    45901 atatgaagct atttatagta tcggggcttg gttgattggt gtggccgtag tcggtctagt
    45961 tgctggtgga ctcaatgttg tcctcgcagc ctatattgcc caaggagttt catccgacct
    46021 tcgggaggat gccttccgta aaattcaaac cttttcttat gctgatattg aacaatttaa
    46081 tgcgggaaat ctagtcgttc gaatgacaaa tgatatcaac cagattcaga acgttgtcat
    46141 gatgaccttc caaattcttt tcagacttcc cctcttgttc atcggttcgt ttatcctagc
    46201 ggttcaaacc ttaccttctc tgtggtgggt gattgttctc atggtagtct tgatttttgg
    46261 tttgactgct gtcatgatgg gaatgatggg gcctcgtttt gccaagtttc aaacccttct
    46321 tgagcgcatc aatgccattg ccaaggaaaa tttacgtggc gttcgtgtgg tcaagtcctt
    46381 tgtccaagaa aaagagcaat ttgctaagtt tacagaggtc tcagacgagc tttttggtca
    46441 aaacctttac attggttatg ccttttcagt agtggaaccc tttatgatgt tggttggtta
    46501 cggggcggtc ttcctctcta tttggctggt cgcgggaatg gttcagtcgg atccgtctgt
    46561 tgttggttcc atcgcttctt ttgttaatta cctaagccag attatcttta ccattgttat
    46621 ggttggattt ttgggaaatt ctgtcagccg tgccatgatt tccatgcgtc gtattcgaga
    46681 aattcttgac gcagagccag ctatgacctt caaggatatc ccagatgaag agttggttgg
    46741 aagccttagc tttgaaaatg tgacctttac ctatccaatg gacaaggaac cgatgctgaa
    46801 agatgtgagc tttactattg aacctggtca aatggttggt gtagttggag cgactggtgc
    46861 aggaaagtca accttggctc aattgattcc acgtctcttt gatccacaga acggggccat
    46921 taaaatcggt ggcaaggata ttcgagaagt gagtgaagga accctgcgta aaacagtttc
    46981 catcgttctc caacgtgcca ttctttttag tggaacgatt gcagataact tgagacaggg
    47041 gaagggaaat gctactctat ttgaaatgga gcgcgcagcc aatattgccc aggctagtga
    47101 attcattcat cgtatggaga aaacctttga aagtccagtt gaagaacggg gaaccaattt
    47161 ctctggtgga caaaaacaaa ggatgtcgat tgcgcgtggg attgtcagca atccacgtat
    47221 tctgattttt gatgattcga cctcagcctt ggatgccaaa tcagagcgct tggtgcaaga
    47281 agctttgaat aaggacttga aggggacgac aaccattatt attgctcaaa aaattagctc
    47341 ggttgtccat gcagacaaga tcttggttct aaatcaagga cgattgattg gtcaaggtac
    47401 gcatgcagac ttggttgcca acaatgccgt ttaccgtgaa atctatgaaa cacagaaatg
    47461 aaagacaaac tataagaaaa gtcaatagtt ttatctaaac tatttcttat ttcaatttga
    47521 tgatttggcg atgattttag agcacggcaa aaggcccttg aaaaagtcca ttttttcaaa
    47581 ggtaatcctg tgttaatttc agaaattaca tcactttttg ttcgtcaaat ggcagctctt
    47641 tttttaggat ataaaacagg gttcggataa gtttttttgc aaggtggatg atggctacat
    47701 tgtaatgttt tccttgttct aatttagtct taagataggc cttaaaagca ggcgaaaagc
    47761 gagggcatgc tttggcagct tgtatgagta cctaccgcag atgaggggaa ctccgtttga
    47821 ccattcttcc tgctaaatca atctgatctg actgataaat agaagaatcc agtccagcga
    47881 aagcttgtaa ttgagcagga ttatcaaagg catgaatatt tcgaatctca gctaaaatga
    47941 ccgcccctaa acgatcccca atcccagtaa ccgtcgtgat gaccgagttg aactcagcca
    48001 tcaagtcatt gacacatgtt tccgccttgt caatgagccc cttgtaatgt ttgatgtttt
    48061 cattacacga gataaaacgt ctatgcgtta tcaaactcat taccaattaa aacaaaaagc
    48121 tgtggttaga tcctttcgga aattgtcaag cgattggagg aaatgaacta atccacagcg
    48181 gcttattcca agtataccac ttgggctttg gcagtagcta actgcgctaa atataatata
    48241 aggaggagta aaatgaagac agttcaattt ttttggcatt attttaaggt ctacaagttc
    48301 tcatttgtag ttgtcatcct gatgattgtt ctggcgactt ttgcccaagc cctctttcca
    48361 gtcttttctg gacaagcggt gacgcagcta gccaatttag ttcaagctca tcaaaatggc
    48421 aatccagaac ttgtatggca aagcctatca ggaatcatgg tcaatcttgg cctgctggtt
    48481 ttggttctat ttatctctag tgtaatatac atgtgtctca tgacgcgcgt gattgcagaa
    48541 tcgaccaacg agatgcgcaa aggtctcttt ggtaagcttg ctcagttgac ggtttctttc
    48601 tttgaccgtc gacaagatgg cgatatcctg tctcatttta ccagtgattt ggataatatc
    48661 ctccaagcct ttaacgaaag cttgattcag gtcatgagca atattgtttt atacattggt
    48721 ctgattcttg tcatgttttc gagaaatgtg acgctggctc tcatcaccat tgccagcacc
    48781 ccattggctt tccttatgct gattttcatc gtgaaaatgg cacgcaaata caccaacctc
    48841 cagcagaaag aggtagggaa gctcaacgcc tatatggatg agagcatttc aggccaaaaa
    48901 gccgtgattg tgcaaggaat tcaagaggat atgatggcag gatttcttga acaaaatgag
    48961 cgcgtgcgca aggcaacctt taaaggaaga atgttctcag gaattctttt ccctatcatg
    49021 aatgggatga gcctgattaa tacagccatc gtcatctttg ctggttcggc tgtacttttg
    49081 aatgataagt ctattgaaac aagtacagcc ctaggtttga ttgttatgtt tgcacaattt
    49141 tcacagcagt actaccagcc tattatccaa gttgcagcga gttggggaag ccttcagttg
    49201 gcctttactg gagctgaacg aattcaggaa atgtttgatg cagaggagga aatccgacct
    49261 gaaaaggctc caaccttcac taagttgcaa gaaagtgttg aaatcagtca tatcgatttt
    49321 tcatacttgc ctgataaacc tattttgaaa gatgtcagca tttctgcccc taaaggccag
    49381 atgacagcag ttgttgggcc gacaggttca ggaaaaacga ctattatgaa cctcatcaat
    49441 cgcttttatg atgttgatgc tggtggtatt tattttgatg gtaaagacat tcgtggctat
    49501 gacttagata gtcttagaag caaggtggga attgtattgc aagattcggt cttgtttagc
    49561 ggaacgattc gagacaatat ccgatttggt gtgccagatg ctagtcagga aatggttgag
    49621 gtagcagcaa aagcaaccca cattcacgac tatatcgaaa gtttgcctga taagtacgat
    49681 actcttattg atgatgacca gagcatcttt tcaacagggc agaagcaatt gatttcaatc
    49741 gctcgaaccc tgatgacaga tccagaagtt ctcattctcg atgaagcaac ttcaaacgta
    49801 gatacggtga cagaaagcaa gattcagcat gccatggagg tggttgtagc aggtagaact
    49861 agtttcgtca ttgcccaccg cttgaaaacc attctcaatg cagatcagat tattgtcctt
    49921 aaagatggag aagtcattga acgtggtaac caccatgaac ttttgaagct aggtggcttt
    49981 tattcagaac tctatcacaa tcaatttgtt ttcgaataag aaagaagttg tcctatgtgg
    50041 gcagcttttt cttgtccata aaaaatgttt atcacagcct taaaaaaaac atattagacg
    50101 aaagtcattt tgagtgatat gataggacta tcgttagcat tcgaaaggag aggcatcatg
    50161 gctagaacgg ttgtaggagt tgctgcaaat ctatgtcccg tagacgcaga aggcaaaatc
    50221 attcattcat ctgtatcttg tagattcgca gagatcattc gtcaagtcgg tggtctccct
    50281 ttagtcattc ctgttggtga tgagtcagtt gtacgtgatt atgtggaaat gattgacaaa
    50341 ctcattttga caggaggcca aaatgttcat cctcagtttt atggagagaa gaagaccgtc
    50401 gagagcgatg attacaatct ggtccgtgac gaatttgaat tggcactctt gaaggaagcg
    50461 cttcgtcaga ataaaccaat tatggcaatc tgtcgcggtg tccaacttgt caatgttgcc
    50521 tttggtggaa ccctcaatca agaaatcgaa ggtcactggc aaggactacc tttcgggaca
    50581 tctcactcta ttgagacagt agaaggaagc gtggtggcta agctatttgg gaaagaaagt
    50641 caggtcaact cagtccatcg tcaaagcatt aaagatttgg cacctaattt ccgtgtaact
    50701 gctattgatt caagagacca aactattgaa gcgattgagt ctatcgacga gcaccgcatt
    50761 atcggtttac agtggcatcc agagtttctg gttaatgaag aagatggcaa tttagaatta
    50821 tttgagtatt tattgaatga actgtaacga ttggaacatc tggtcgttct ttcttttatt
    50881 ttttcaaaat ttttagaatg tggcatttta cgcaaacgtt tgaattctga taaaaattgg
    50941 agaaattcga caaaaaaact tgaaaaaaac gaaggtaagc gttatgatag aaaagaagaa
    51001 atattggagg aagaacatgt cacatattaa atttgattat tcaaaagttt tagacaaatt
    51061 tgttgcacca catgaagtgg aatacatgca atcacaagta acagcagcag atgaattgat
    51121 ccgtaaagga actggtgctg gtagcgactt cttgggatgg ttggaccttc ctgaaaaata
    51181 cgaccgcgaa gaatttgacc gcatcttgaa agctgctgag caaatcaagt cagacagcga
    51241 tgttttggtt gtgatcggta ttggtggatc ttaccttggt gcaaaagcag caatcgactt
    51301 cttgaatcac cattttgcta acttgcaaac aaaagaagaa cgcaaagctc cacaaatcct
    51361 ttacgcagga aactcaatct catctactta ccttgctgac ttggtagagt atgttgcaga
    51421 caaagacttc tcagtaaacg taatttctaa atcaggtaca acaactgaac cagcgattgc
    51481 tttccgtgtc tttaaagaac tcttggttaa gaaatacggt caagaagaag ctaacaaacg
    51541 tatctatgca acaactgacc gccaaaaggg tgctgttaag gttgaagcag acgctaacgg
    51601 ttggggaaca tttgttgttc cagatgatat cggtggacgc ttctcagtat tgacagccgt
    51661 tggtttgctt ccaatcgcag catcaggagc tgacataaaa gctcttatgg aaggtgcgaa
    51721 tgcagctcgc aaagactaca cttcagacaa aatctctgaa aacgaagctt accaatacgc
    51781 agtcgttcgt aacatccttt atcgtaaagg ctatgcaact gagatcttgg taaactatga
    51841 gccatcactt caatacttct cagaatggtg gaaacaattg gctggtgaat cagaaggaaa
    51901 agaccaaaaa ggtatctacc caacttcagc caacttctca actgacttgc actcacttgg
    51961 tcaatttatc caagaaggaa ctcgtatcat gtttgaaaca gttgtccgtg ttgacaaacc
    52021 tcgtaaaaac gtgcttattc ctactttgga agaagacctt gacggacttg gttaccttca
    52081 aggaaaagac gttgactttg taaacaaaaa agcaactgac ggtgttcttc ttgcccacac
    52141 agatggtgat gtaccaaaca tgtatgtgac tcttccagag caagacgctt tcactcttgg
    52201 ttacactatc tacttcttcg aattggcaat tgccctttca ggttacttga atgctatcaa
    52261 cccatttgac caaccaggtg ttgaagctta taaacgtaac atgtttgccc ttcttggaaa
    52321 accaggattt gaagaattga gcaaagaact taacgcacgt ctataataga agaaaagagt
    52381 ggtttgccca ctctttttac tctctttatc catagaaatt ggactcagcc aagacttgtg
    52441 atataatata gaaagcaaaa aggcagacgc ctagataata ggagaaacta tgtcaaaaga
    52501 tatccgcgta cgttacgcac caagtccaac aggactacta cacatcggaa atgcccgtac
    52561 agcattgttt aactacttgt atgcgcgcca tcatggtgga acatttctca tccgtatcga
    52621 agatactgac cgtaaacgcc atgtcgagga tggtgaacgt tcacaacttg aaaaccttcg
    52681 ctggttaggc atggattggg atgaaagtcc agaatcacat gagaattatc gccagtctga
    52741 gcgtttggac ttgtatcaaa aatacatcga ccaactatta gctgaaggaa aagcctacaa
    52801 atcttacgtt acagaagaag agttggcagc tgaacgtgaa cgtcaagaag tagctggcga
    52861 aacaccacgc tacatcaatg aataccttgg tatgagtgaa gaagaaaaag cagcttacat
    52921 cgcagaacgt gaagcagcag ggatcatccc aactgttcgt ttggctgtca atgagtcagg
    52981 tatctacaag tggcatgata tggtcaaagg cgatatcgaa tttgaaggtg gcaatatcgg
    53041 tggtgactgg gttatccaaa agaaagacgg ttacccaact tacaactttg ccgttgttat
    53101 cgatgaccac gatatgcaaa tctctcatgt tatccgtgga gatgaccata ttgctaatac
    53161 accaaaacag cttatggtct atgaagctct tggttgggaa gctccagagt tcggtcacat
    53221 gaccttgatt atcaactctg agactggtaa gaagttatct aaacgtgata ctaatacact
    53281 tcaatttatc gaagattacc gaaagaaagg ttaccttcca gaagcagtct ttaactttat
    53341 tgctcttctt ggttggaacc caggtggtga agatgagatt ttctctcgtg aagaactcat
    53401 taaacttttt gatgaaaacc gcctcagcaa gtcaccagca gcctttgatc agaaaaaact
    53461 agactggatg agcaatgatt atatcaagaa tgcagacctt gaaaccatct ttgaaatggc
    53521 aaaaccattc ttagaggaag caggccgttt gactgacaag gctgaaaaat tagttgagct
    53581 ctataaacca caaatgaaat cagtagatga gattatccca ttgacagatc ttttcttctc
    53641 agatttccca gaattgacag aagcagagcg cgaagtcatg acgggtgaaa cagttccaac
    53701 agttcttgaa gcattcaaag caaaacttga agcgatgaca gatgataaat ttgtgacaga
    53761 aaatatcttc ccacaaatta aagcagttca aaaagaaaca ggtattaaag ggaaaaatct
    53821 tttcatgcct attcgtatcg cagtttcagg cgaaatgcat gggccagaat taccagatac
    53881 aattttcttg cttggacgtg aaaaatcaat tcagcatatc gaaaacatgc taaaagaaat
    53941 ctctaaataa agaggataca ataatggaca tctgggaaaa gatgtacgaa gaagcacaga
    54001 aactatacaa tccacatgaa gtatcagact ttgtttatgc caatcatgtt gtagctgcag
    54061 tagaagcaga agatggacaa atatttacag gattctgtat ggagggaacc tgtggtgttt
    54121 tccatctctg cgcagaacgg gcgaccctct tcaatatgta ccaattttca ggacaaacta
    54181 aggttaagaa agtattagcc tttcgagaca aaccacctta tggtggaagt tcagccatgc
    54241 cttgcggtgc ttgtagagaa ttccttttag agcttaatgc tgaaaataaa gatgcagaat
    54301 tcatgatgga ctataatata agaaaaacag ttaaagtcgc agaactaatc ccttattggt
    54361 ggggagaaga acgtgcttct aagtttaatg agcgatagaa gagtcagtat aattctggct
    54421 ttttttacta taagttgaaa
//
LOCUS       DAYYYC010000009        52882 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.009, whole genome shotgun sequence.
ACCESSION   DAYYYC010000009 DAYYYC010000000
VERSION     DAYYYC010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52882
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.009"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            265..501
                     /gene="comW"
                     /locus_tag="ACHBV5_000509"
     CDS             265..501
                     /gene="comW"
                     /locus_tag="ACHBV5_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma(X)-activator ComW"
                     /protein_id="HFM9966367.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            732..2018
                     /locus_tag="ACHBV5_000510"
     CDS             732..2018
                     /locus_tag="ACHBV5_000510"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFM9966368.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            2219..2686
                     /gene="tadA"
                     /locus_tag="ACHBV5_000511"
     CDS             2219..2686
                     /gene="tadA"
                     /locus_tag="ACHBV5_000511"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFM9966369.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            2719..2812
                     /gene="ffs"
                     /locus_tag="ACHBV5_000512"
     ncRNA           2719..2812
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACHBV5_000512"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            2872..3315
                     /locus_tag="ACHBV5_000513"
     CDS             2872..3315
                     /locus_tag="ACHBV5_000513"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFM9966370.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            3317..3832
                     /locus_tag="ACHBV5_000514"
     CDS             3317..3832
                     /locus_tag="ACHBV5_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFM9966371.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     TPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            3846..5207
                     /gene="radA"
                     /locus_tag="ACHBV5_000515"
     CDS             3846..5207
                     /gene="radA"
                     /locus_tag="ACHBV5_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFM9966372.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYISGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            5280..5777
                     /locus_tag="ACHBV5_000516"
     CDS             5280..5777
                     /locus_tag="ACHBV5_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HFM9966373.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            5798..6079
                     /locus_tag="ACHBV5_000517"
                     /pseudo
     CDS             5798..6079
                     /locus_tag="ACHBV5_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            6139..7490
                     /locus_tag="ACHBV5_000518"
     CDS             join(6139..6580,6580..7490)
                     /locus_tag="ACHBV5_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFM9966374.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNSMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG
                     "
     gene            7493..8056
                     /locus_tag="ACHBV5_000519"
                     /pseudo
     CDS             7493..8056
                     /locus_tag="ACHBV5_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family glutamic-type intramembrane
                     protease"
     gene            8201..9169
                     /locus_tag="ACHBV5_000520"
     CDS             8201..9169
                     /locus_tag="ACHBV5_000520"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFM9966375.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            9287..10214
                     /locus_tag="ACHBV5_000521"
                     /pseudo
     CDS             9287..10214
                     /locus_tag="ACHBV5_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175244.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            10823..13456
                     /gene="polA"
                     /locus_tag="ACHBV5_000522"
     CDS             10823..13456
                     /gene="polA"
                     /locus_tag="ACHBV5_000522"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFM9966376.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVGTEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            13541..13978
                     /locus_tag="ACHBV5_000523"
     CDS             13541..13978
                     /locus_tag="ACHBV5_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFM9966377.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(14214..15224)
                     /locus_tag="ACHBV5_000524"
     CDS             complement(14214..15224)
                     /locus_tag="ACHBV5_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HFM9966378.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSIVLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            15373..16542
                     /locus_tag="ACHBV5_000525"
     CDS             15373..16542
                     /locus_tag="ACHBV5_000525"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFM9966379.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEVFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            16539..17309
                     /gene="recO"
                     /locus_tag="ACHBV5_000526"
     CDS             16539..17309
                     /gene="recO"
                     /locus_tag="ACHBV5_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFM9966380.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKCMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            17306..18298
                     /gene="plsX"
                     /locus_tag="ACHBV5_000527"
     CDS             17306..18298
                     /gene="plsX"
                     /locus_tag="ACHBV5_000527"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFM9966381.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            18304..18537
                     /locus_tag="ACHBV5_000528"
     CDS             18304..18537
                     /locus_tag="ACHBV5_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFM9966382.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            18583..18873
                     /locus_tag="ACHBV5_000529"
                     /pseudo
     CDS             18583..18873
                     /locus_tag="ACHBV5_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            19076..19306
                     /gene="blpU"
                     /locus_tag="ACHBV5_000530"
     CDS             19076..19306
                     /gene="blpU"
                     /locus_tag="ACHBV5_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HFM9966383.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            19309..19434
                     /locus_tag="ACHBV5_000531"
     CDS             19309..19434
                     /locus_tag="ACHBV5_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HFM9966384.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            20021..22174
                     /gene="comA"
                     /locus_tag="ACHBV5_000532"
     CDS             20021..22174
                     /gene="comA"
                     /locus_tag="ACHBV5_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HFM9966385.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            22187..23536
                     /gene="comB"
                     /locus_tag="ACHBV5_000533"
     CDS             22187..23536
                     /gene="comB"
                     /locus_tag="ACHBV5_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HFM9966386.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKVTASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKYVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            23706..24413
                     /gene="purC"
                     /locus_tag="ACHBV5_000534"
     CDS             23706..24413
                     /gene="purC"
                     /locus_tag="ACHBV5_000534"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFM9966387.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNVAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            24415..24558
                     /locus_tag="ACHBV5_000535"
     CDS             24415..24558
                     /locus_tag="ACHBV5_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFM9966388.1"
                     /translation="MFATENLRLSTKRTQAEKVPQTFSLCRELGELTDVYEIVWEKLQ
                     GLK"
     gene            24615..28340
                     /locus_tag="ACHBV5_000536"
     CDS             24615..28340
                     /locus_tag="ACHBV5_000536"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HFM9966389.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            28433..29875
                     /gene="purF"
                     /locus_tag="ACHBV5_000537"
     CDS             28433..29875
                     /gene="purF"
                     /locus_tag="ACHBV5_000537"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFM9966390.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGVEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            30094..31116
                     /gene="purM"
                     /locus_tag="ACHBV5_000538"
     CDS             30094..31116
                     /gene="purM"
                     /locus_tag="ACHBV5_000538"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFM9966391.1"
                     /translation="MANKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIAGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            31113..31658
                     /gene="purN"
                     /locus_tag="ACHBV5_000539"
     CDS             31113..31658
                     /gene="purN"
                     /locus_tag="ACHBV5_000539"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFM9966392.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            31742..32251
                     /locus_tag="ACHBV5_000540"
     CDS             31742..32251
                     /locus_tag="ACHBV5_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFM9966393.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            32276..33823
                     /gene="purH"
                     /locus_tag="ACHBV5_000541"
     CDS             32276..33823
                     /gene="purH"
                     /locus_tag="ACHBV5_000541"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFM9966394.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAANENQIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            33945..35207
                     /gene="purD"
                     /locus_tag="ACHBV5_000542"
     CDS             33945..35207
                     /gene="purD"
                     /locus_tag="ACHBV5_000542"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFM9966395.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTATYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            35464..35580
                     /locus_tag="ACHBV5_000543"
     CDS             35464..35580
                     /locus_tag="ACHBV5_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HFM9966396.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            35610..36098
                     /gene="purE"
                     /locus_tag="ACHBV5_000544"
     CDS             35610..36098
                     /gene="purE"
                     /locus_tag="ACHBV5_000544"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFM9966397.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            36085..37176
                     /gene="purK"
                     /locus_tag="ACHBV5_000545"
     CDS             36085..37176
                     /gene="purK"
                     /locus_tag="ACHBV5_000545"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFM9966398.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            37186..37413
                     /locus_tag="ACHBV5_000546"
     CDS             37186..37413
                     /locus_tag="ACHBV5_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HFM9966399.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            37476..38774
                     /gene="purB"
                     /locus_tag="ACHBV5_000547"
     CDS             37476..38774
                     /gene="purB"
                     /locus_tag="ACHBV5_000547"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFM9966400.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(38829..42767)
                     /gene="strH"
                     /locus_tag="ACHBV5_000548"
     CDS             complement(38829..42767)
                     /gene="strH"
                     /locus_tag="ACHBV5_000548"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HFM9966401.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLETLDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(43082..43798)
                     /locus_tag="ACHBV5_000549"
     CDS             complement(43082..43798)
                     /locus_tag="ACHBV5_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFM9966402.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            44146..45933
                     /locus_tag="ACHBV5_000550"
     CDS             44146..45933
                     /locus_tag="ACHBV5_000550"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HFM9966403.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            45930..46406
                     /locus_tag="ACHBV5_000551"
     CDS             45930..46406
                     /locus_tag="ACHBV5_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM9966404.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            46434..47339
                     /locus_tag="ACHBV5_000552"
     CDS             46434..47339
                     /locus_tag="ACHBV5_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFM9966405.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVADKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            47326..48141
                     /locus_tag="ACHBV5_000553"
     CDS             47326..48141
                     /locus_tag="ACHBV5_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFM9966406.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            48148..48552
                     /locus_tag="ACHBV5_000554"
     CDS             48148..48552
                     /locus_tag="ACHBV5_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFM9966407.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            48805..49971
                     /locus_tag="ACHBV5_000555"
     CDS             48805..49971
                     /locus_tag="ACHBV5_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFM9966408.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKV
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTAYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            50087..51124
                     /locus_tag="ACHBV5_000556"
     CDS             50087..51124
                     /locus_tag="ACHBV5_000556"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFM9966409.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     IYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            51332..52186
                     /locus_tag="ACHBV5_000557"
     CDS             51332..52186
                     /locus_tag="ACHBV5_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFM9966410.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWNIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            52336..52593
                     /locus_tag="ACHBV5_000558"
     CDS             52336..52593
                     /locus_tag="ACHBV5_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFM9966411.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVKSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(52701..>52882)
                     /locus_tag="ACHBV5_000559"
     CDS             complement(52701..>52882)
                     /locus_tag="ACHBV5_000559"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966412.1"
                     /translation="TDEVSNHIYGKVKLTWFEEIFEEYKSPHNKTHTIKVFMYCPPKV
                     RQKESNFWGAVHFNT"
BASE COUNT        14930 a         9827 c        12569 g        15556 t
ORIGIN      
        1 tgaatttttt tatactagaa aatcagaacc ataataccta tataaaaata ttatagtttt
       61 aataggattt acccaaaagt tttaaggcgg tctttttaga actttaattg tttgaaattt
      121 aggtagcaaa tttgtttcta ttttgtcaac ttttcctatt tttatcttgt tgaggctggt
      181 attttaacaa ttcaggaatt gatagtgaat gtgtaaaatt ttttgttaga ataagtttat
      241 aaaaaagaaa aggagtattt gattatgtta caaaaaattt atgagcagat ggctaatttc
      301 tatgatagta ttgaagaaga gtatggtcct acatttggtg ataattttga ctgggaacat
      361 gttcatttta aatttttaat ttattattta gtgagatatg gcattggttg tcgtagggat
      421 tttatcgttt accattatcg tgttgcttat cgtttgtatc ttgaaaaatt ggtaatgaat
      481 cgggggttta tttcttgttg aggtaatttt agtaaatttc cgaactaatt tactctttta
      541 tggaaagata atagtaaata gctagtaatt tttctaaatc attttttaat agttggaaat
      601 agcaaatctt tctattgttt cttcttgata aaaaggcgat tttttattat aataaattgt
      661 aagatataat tgcaggtgag agtcctgcca tgtatgtgag aaaggaagag cctgagggct
      721 cagacaaaat tatgacttca gttgttgttg taggtaccca atggggtgat gaaggtaaag
      781 ggaagattac agacttcctt tcagcgaatg cagaagtaat tgcacgttac caaggtggtg
      841 ataatgctgg tcacacgatt gtgattgacg gtaagaaatt taagttgcac ttgattccat
      901 ctgggatttt cttccctgaa aaaatatctg tcattgggaa tggtatggtt gtaaatccta
      961 aatctcttgt aaaagagttg agctatcttc atgaggaagg tgtaacaact gataacttgc
     1021 gtatttctga tcgtgcgcat gttattttgc cttatcatat cgagttggat cgcttgcaag
     1081 aagaagctaa gggcgacaat aagattggta cgacaattaa gggaattggt ccagcttata
     1141 tggacaaggc tgctcgtgtt ggaattcgta ttgcagatct tttagataaa gatattttcc
     1201 gtgagcgttt agaacgtaac cttgctgaaa agaatcgtct ttttgaaaaa ttgtatgaca
     1261 gtaaagcgat tgttttcgat gatatttttg aagaatatta cgaatatggt caacaaatca
     1321 agaaatacgt gatagataca tctgttatct tgaatgatgc gcttgataat ggcaaacgtg
     1381 tgctttttga aggtgcacaa ggtgttatgc tagatatcga ccaaggtact tatccatttg
     1441 ttacgtcatc aaaccctgta gctggtggtg tgacaattgg ttctggtgtc ggtccaagca
     1501 agattgacaa ggttgtaggt gtatgtaaag cttatacgag tcgtgtagga gatggtcctt
     1561 tcccaactga gttgtttgat gaagtgggag aacgtatccg tgaagtgggt catgaatatg
     1621 gtacaacaac tggtcgtcca cgtcgtgtag gttggtttga ctcagttgtg atgcgtcata
     1681 gccgtcgtgt ttctggtatt actaaccttt ctttgaactc tattgatgtt ttgagcggtt
     1741 tggatactgt gaaaatctgt gtggcctatg atcttgacgg tcaacgtatt gactactatc
     1801 cagctagtct tgagcaattg aaacgttgca agcctatcta tgaagagttg ccaggttggt
     1861 cagaagatat taccggagtt cgcaatttgg aagatcttcc tgagaatgcg cgtaactatg
     1921 ttcgtcgtgt gagtgaattg gttggcgttc gtatttctac tttctcagta ggtcctggtc
     1981 gtgaacaaac aaatatttta gaaagtgttt ggtcctaaga gatttttaag atttgtttaa
     2041 gataggtcgg gtatactata gacggttaca agaagacctc ctaacttgtt gtaacaaata
     2101 tcctaaactt ttctttttca taataatctc cctatagagt caccgcattc ggtggcttct
     2161 tttgtgttgg gattcatgat ataataataa aatcgataag taggaaaaga gaaaagagat
     2221 gtattatacg cttgaagaaa aagaagtctt tatgagggag gctttgagag aggctgagat
     2281 tgctcttgaa cacgatgaaa ttccaattgg ttgtgtgatt gtcaaagatg gggaaatcat
     2341 tggtcgtggg cataatgcgc gtgaggaatt acagcgagcg gttatgcatg cggaaattat
     2401 ggctatagag gatgcgaact tgagtgagga gagctggcgc ttgctggatt gcacactttt
     2461 tgtgaccatt gaaccttgtg tcatgtgtag tggagcgatt gggcttgccc gcattccaaa
     2521 tgtggtctat ggggctaaaa accagaaatt tggcgctgct gggagtttgt acaatatctt
     2581 gacagatgag cgtctcaatc atcgtgtgga ggttgaaata ggaattttgg aagatgaatg
     2641 cgcagctatc atgcaggatt tttttagaaa tagacggaaa aaataatttt gcttttaaaa
     2701 tgaataggaa tgtgatataa taaatagtgg agcaacagtt ctgcgtgaag cgggtcaggg
     2761 gaggaatcca gcagccctaa gcgatttgaa ttgtgtgctc ttttttcgtg ctttttccga
     2821 ataaataaga tagaataatc tagaataaat gataatagaa aagagaaaat tatgaaaatt
     2881 cgtggttttg aattggtttc gagttttaca gatgaaaatt tattgcccaa gcgtgagaca
     2941 gcgcatgcgg ctggttacga cttaaaggtt gctgtgcgta cagttgttgc gccaggagag
     3001 attgtcttgg ttccgacagg ggttaaggct tatatgcagc cgactgaggt tctctacctc
     3061 tatgatcgtt cttcaaatcc tcgtaagaag ggcttggttt taattaactc agttggggtc
     3121 attgatgggg attattatgg aaatcctgga aatgaagggc atatttttgc gcagatgaag
     3181 aatatcacag accaagaggt tgttcttgaa gttggggaac gtattgtcca ggctgttttt
     3241 gctactttct taattgcaga tggagatgca gctgatggcg ttcgaactgg tggatttgga
     3301 tcgacagggc actagaatga agattatctt tgtacgtcat ggggagccag attaccgtga
     3361 gttagaggag cgttcttata taggatttgg gatagatttg gcacccttgt ctgagatggg
     3421 acggcagcaa gtccagaaat tgagcaaaac tcctttactc tcgtcagctg aaataatcgt
     3481 atcttctgca gtcacaagag ctttagaaac ggcttcgtat gtggtctgtg ctacgggtct
     3541 tcctttaaga gtagagcctt tattacatga atggcaggtc tataaaacag gaatagaaaa
     3601 ctttgaaaca gctagaagac tgtttttaga aaacaagggg gagttgcttc ctaatagtcc
     3661 tattcaatat gagacagcta cggaaatgaa gtctcggttt ctagaatgta tgtctaagta
     3721 tcgagaacat cagactgtgg tagttgttgc tcatcgaatg ctcatgcgcc agtttgtgcc
     3781 aaatgagaag attgattttt gccaagtgat tgagtgtgag ttagagatat agaaagaggt
     3841 ttgtcatcgc aaagaaaaaa gcgacatttg tatgtcaaaa ttgtgggtat aattccccta
     3901 aatatctggg acgttgcccc aactgtgggt cttggtcttc ttttgtggaa gaggttgagg
     3961 ttgccgaggt caagaatgcg cgtgtgtcct tgacaggtga gaaaaccaag cccatgaaac
     4021 tagctgaggt gacttccatc aatgtcaatc gaaccaagac ggagatggag gaattcaacc
     4081 gtgtgcttgg aggcggagtg gtaccaggaa gtctcgtcct catcggtggg gatcctggga
     4141 ttgggaaatc aactcttctc ctacaagtct caacccagtt gtcccaagtg gggacagttc
     4201 tctatatcag tggggaggag tctgcccagc agattaaact acgtgcagag cgcttaggtg
     4261 atattgatag tgagttttat ctctatgcag agaccaatat gcagagtgtt cgtgcagaag
     4321 tggagcgtat ccagccagac tttcttatta ttgattccat ccagaccatc atgtctcctg
     4381 agatttcagg ggtgcagggg tctgtttctc aggtacgtga agtgaccgct gaactcatgc
     4441 agttggccaa gaccaataac attgccatct ttatcgtagg tcatgtgacc aaagaaggaa
     4501 ccttggctgg gcctcgtatg ttggagcata tggtggatac ggtgctttac tttgaagggg
     4561 agcgtcacca cacctttcgt attttgagag cggtcaaaaa tcgttttggt tccactaatg
     4621 agattgggat ttttgagatg cagtcgggcg gcttggttga ggtactcaat ccgagtcaag
     4681 ttttcctaga agagcgtttg gatggggcaa ctggttcctc catcgttgta accatggaag
     4741 ggacgcgtcc gattttggcg gaggttcagg ctttggtaac accgaccatg tttggaaatg
     4801 ccaagcgtac tacgacagga cttgatttta accgtgctag cttgattatg gctgttttgg
     4861 aaaaacgggc agggcttctc ttgcaaaatc aggatgccta tctcaaatct gctggtggtg
     4921 ttaaattgga tgaacctgcc attgacttgg ctgttgcagt tgctattgct tcgagctaca
     4981 aagacaagcc aactaatcct caggaatgtt ttgtcggaga actgggcttg acaggagaga
     5041 ttcggcgcgt gaatcgtatt gagcaacgca tcaacgaagc tgctaaactg ggctttacta
     5101 agatttatgt acctaagaat tccttgacag gaatcactct gcctaaggaa attcaggtca
     5161 ttggcgtgac aacgattcag gaagttttga aaaaggtctt tgcataatcc gtgacaaatt
     5221 ctcttaaaaa tgataagata ggagaaatat ttgactatca aattttcaag gagggaatcg
     5281 tgtcgtattt tgaacagttt atgcaagcta atcaggctta tgttgcccta catgggcagt
     5341 taaatctgcc acttaaaccc aaaacaagag tagctattgt gacctgtatg gactcacgtt
     5401 tgcacgttgc gcaagctcta ggtttggcac ttggggatgc tcatatcttg cggaatgcag
     5461 gtggtcgagt gactgaagac atgattcgtt cgctagttat ttcccagcaa caaatgggga
     5521 caagagagat tgtggtattg caccatacag actgtggtgc tcagaccttt gaaaatgaac
     5581 cttttcagga gtatttaaaa gaggaattag gtgtagatgt gtcagaccag gacttcttgc
     5641 ccttccaaga tatagaagag agtgtacgcg aggatatgca actgcttatc gagtctcccc
     5701 taataccaga cgatgtcatt atctctggtg ctatttacaa tgttgataca ggaagtatga
     5761 cagtcgtaga attataaata cttcatttag aaagaaagtg tatgaagaaa agcagtattt
     5821 tatttttatt ttattgctat gtattggttt acagtatgaa accatctact atacggacgg
     5881 ttcgaggtca ggtgcggaat atggactaat gggagtttct atctttctag ctctctttta
     5941 catgattccg gctctttatt ttctcttccg tattgggaaa aaatgggaat tgccaaagaa
     6001 ggttttgatt ctgtctttat tgggagggat gttcctttca ggctggttgt ctagttttgc
     6061 taatacttat atccatgatt ttatgaactg caccccaaaa gttagacaga aaaaatctaa
     6121 cttttggggt gttttattat gaaattgagt tatgaagata aagttcagat ctatgaacta
     6181 agaaagcaag gacaaagctt caaacagctt tcaaaaagat ttggtgtgga tgtttctggt
     6241 ctaaagtaca tggtgaaatt aattgaccgt tatggcatag aaatcgttaa aaaagggaag
     6301 aatcgtcact attcttctaa attgaaacaa gaaatgatgg ataaagcctt actggaaggt
     6361 tgttcacaaa gaagtattag tcttgattat gccctcccaa accaaggaat gctttcattt
     6421 tggccggcac aatacaagaa aaacgggtat actattgttg agaaaacaag agggagacca
     6481 gctaaaatgg gacgtaaacg gaagaagact tgggaagaaa tgacagaact agaacgactc
     6541 caggaggaga atgaacgctt acggactgag gtggcctacc taaaaaagtt aaaagagtta
     6601 gaggaaaggg acgaagccct agagcgagaa aggcagagac agttagagaa atggtttcag
     6661 gaggatttcg actagatttt cttcttgaaa cagcacgttt agctcgctcg acttactatt
     6721 atcagttgaa acaactggat ggggttgata aagataaaga gattaaaacc gaaattcagg
     6781 gcattgataa tgaacataaa ggcaactatg gctatcgtcg aatccattta gaactaagga
     6841 atcgtggttt tgtggtcaat cataagaaag ttcaacggtt gatgagaatt cttggtttaa
     6901 cggctcgaat tcgccgtaaa cggaagtatt cttcctacca aggagagatt ggcaagaaag
     6961 cagagaatct cattcaacgc cagttcgaag catcgaggcc aatggaaaag tgctatacag
     7021 atgtgacaga gtttgccatt ccaaatagca cacagaaact ctatttatca ccagttttag
     7081 atggttttaa cagtgaaatc attgcttatc atctttctac ttcgccaaac ttagaacaag
     7141 tgaagagtat gttagaacag gcctttacag agaaatacta tgagaatacg attctccata
     7201 gtgaccaagg ctggcaatac caacacgatt cttatcatcg gttcctagag agtaagggaa
     7261 ttcaagcatc catgtcacgc aagggcaaca gcccagacaa cagcatgatg gaatctttct
     7321 ttggcatttt aaaatccgaa atgttttatg gctatgagaa gaactttaga tctttagaaa
     7381 accttgaaca agctattgtg gactacattg attactacaa caacaaacga attaaggtaa
     7441 aactaaaagg acttagttct gtgcagtaca gaactaaatc ctttggataa attatttgtc
     7501 taactttttg gggtcagtac atttactggg ggttcttttc ccagatagta catttttaaa
     7561 tgcctttgaa agtgctattg tggctccttt ggtagaagaa tccttgaaat tattgccact
     7621 tgtttttgtt ttggctttga ttcctgtgcg aaaattaaaa tctttgtttt tacttggaat
     7681 tgcttccggt ttgggattcc aaatgattga ggatattggt tatattcata cggatttgcc
     7741 agagggcttt gactttacta tttcgcgaat tttagagcgt atcatctcag gaattgcctc
     7801 tcactggact ttttcaggtc tagctgtagt aggtgtttac ttgctttaca gagcctataa
     7861 aggacagaag gttggcaaga aacagggcct tatttttcta ggtttagcct tgggaactca
     7921 cttcttgttt aactctcctt ttgtggagtt ggaaacagag ttgcctttag cgattccagt
     7981 ggttacggct attgctctct atggttttta tcatgcttat tgctttgttg agaaacacaa
     8041 tgagttgatg acctagaata tttttcaaaa gaatgatgca agggtacaaa tatggtgccc
     8101 ttcttttatt tttgattgaa aaatagtgca aaaagcgcta caatggtaga tggaaaatct
     8161 tgtgaaaagc acaagttata catatatacc ggaggaaatc atgtcttttt ctgatttaaa
     8221 gctatttgcc ctttcttcta ataaagaatt ggcagaacgt gtggcgcagg agattgggat
     8281 agagttgggg aaatcaagtg ttcgccaatt ttcagatgga gagattcagg tcaacattga
     8341 agaatcaatc cgtgggaaac acgtctttat cctacaatca actagttcgc ctgtaaatga
     8401 caatctgctt gaaattttga ttatggtaga tgctttgaag cgtgcgagtg cagaatctgt
     8461 caatgttgtc atgccttact atgggtatgc acgtcaggat agaaaggcga gagcgcgtga
     8521 gccaatcact tcaaaacttg tcgcaaatat gcttgaagta gctggagtgg atcgtttatt
     8581 gaccatcgac ttgcatgctg cgcaaattca aggattcttt gatattcctg tggatcattt
     8641 gatgggtgct cctctgattg cagattattt tgagcgtcgt ggtatggttg gttctgacta
     8701 tgtggttgtc agcccggacc atggaggggt gactcgtgct cgtaagttgg cagaattttt
     8761 gaaaacttct atcgctatta ttgataaacg tcgtagcgtt gataagatga atactagtga
     8821 agttatgaac atcatcggta aggttgaagg caagacttgt atcttgattg atgatatgat
     8881 tgataccgct ggaacgattt gtcatgcggc agatgctctt gcggaagctg gtgctgttga
     8941 agtctatgca agctgtacgc acccagttct ttctggtcct gctacggaca atatccaaaa
     9001 atcagctatt aagaaattgg ttgttttgga taccatctat ctgccagaag agcgtttgat
     9061 tgataagatt gagcagattt caatcgctca tctcctaggg gatgctatcg tacgtattca
     9121 tgaaaaacga ccactttctc cacttttcga tattgagaaa aaaatttaat gaccaagcct
     9181 gagatgattc tcaggttttt tcgtcttttt tccgaataaa tagatagtag cggtgaatct
     9241 agtaaagcta gatttaaaac tgtgatataa taaaaagaga agaaatatga ctgtacgtca
     9301 tccgggcatt agcccaacca atgacttggt agctaagaaa atctttagca atccagaaat
     9361 tacttgtcaa tttattcgcg atatgctgga tttgccagcc caaaatgtga ccattttgga
     9421 gggtagcaat attcacgtat tactctccat gccttactcg gtgcaggatt tttataccag
     9481 tatagacgtc ttggcggagt tggataacgg tactcaagta attattgaga ttcaagtcca
     9541 tcatcagaat tttttcatca atcacttgtg ggcttacctg tgcagtcagg ttaatcaaaa
     9601 tcttgaaaaa attcgtcagc gagaaggtga tactcactag atctacaaac acatcgctcc
     9661 tgtttacgtc attgctatcg tggatagcaa ttatttctca gatggcctgg cttttcatag
     9721 cgttagtatg cgcgaagaca caacaggtga ggtattggcg attaccaaca atggacagga
     9781 aaaccatctg gttaagatgg cattcttgga attaaaaaat acagagaaac cagcaaagac
     9841 aaggttcgca agccatggtt ggagtttttc ggcaacaagc cctttaccca gcaaccgcaa
     9901 cgagccatta cccaagcaaa tcaactgctg gactacaaga gctggtccga ggaggacagg
     9961 aaaatgttta gtcaactaca tatgcgagaa gaacaagtct tgttagcaca ggactatgcg
    10021 aaggtattga acaaggacta gagcgtggta ttgaacgtgg tcgtgcagag ggttgtgaac
    10081 aaggacgaga agaaggcctt gaagagggat taaaagtagg tttagtaaat ctagtacgtc
    10141 aaggtcttct aacacctgag gttgcgagtg agcaattagg catgaccgtg gctgagtttg
    10201 agtccttgct atgagttcat actttatata gtagaaagtt gatgggatgg caagtttatt
    10261 atcaaaatac ttgtcatttt tgcttgacat ttctatcttt ttataagata tagtaaaatg
    10321 aaataataac aggacaaatc gttcaggaca gtcaaatcga tttctaacaa tgttttagaa
    10381 atcgaggtgt actattctag tttcaatcta ctatagtatt agcgaagtaa gttatgtctc
    10441 gctattcgta cagtttggat agtcgcaaga ttgtctttga aatttcctgt tttaaagaga
    10501 aaaaagcctc tttgacgcta ttttttcatc tttttgaaag ttctataatg aagttagcca
    10561 cccagccctc cttttcctcc ttctatagtg agttgaaata agatgtgaaa caactctatc
    10621 aggaaagtca aattaattta tagaaatatt ttagcagtca aggtgtacta ttatagattc
    10681 aatatactat attatatcac atttttaaat ctaggtttac taaattctct ggctctatct
    10741 atttattcgg aaaaagtttg aaaaatactt gctctagctc ttcccaatgg tattttttga
    10801 ttctttcctt tataatgggt gtatggataa gaaaaaatta ttattgattg atgggtcttc
    10861 tgtagctttt cgggcgtttt ttgcgctgta tcagcagttg gaccgtttta agaatgcggc
    10921 tggtttgcat accaatgcga tttatggttt tcagttgatg ttgagtcatt tgttggagcg
    10981 ggttgagccg agtcatattt tggtggcttt tgatgcggga aagacgacct tccggacaga
    11041 gatgtatgcg gactataagg gtggtcgggc caagactcct gatgagtttc gtgagcaatt
    11101 tcctttcatt cgtgagttgc tggatcatat ggggattcgt cactatgagc tggctcagta
    11161 tgaggcggat gacatcattg ggacgctgga taagctagca gagcaggatg gttttgatat
    11221 taccattgtc agtggggaca aggatttgat tcagctgacg gatgagcata cggtggttga
    11281 aatttccaag aaaggtgtgg ctgagtttga ggcctttacg ccagattacc tcatggaaga
    11341 aatgggcctc acaccagctc agtttatcga tctcaaggcg ctcatgggtg ataagtcgga
    11401 taatatccct ggggtgacca aagtcggtga aaagacgggt attaagctct tgctggagca
    11461 tggttcgctt gaggggattt atgaaaatat tgatggaatg aagacttcta agatgaagga
    11521 aaatctcatc aatgacaagg aacaggcctt tttgtctaaa acactagcga ccattgatac
    11581 caaggcaccg attgcgattg gtttagagga cttggtctat agtggtccag atgttgaaaa
    11641 tcttgggaaa ttttacgatg agatgggctt caaacagctc aagcaggctt taaatgtgtc
    11701 gtcagctgat gtggctgagg gtttggattt tactattgtt gaccaaatca gtcaagatat
    11761 gctgagtgaa gagtctatct tccactttga gctttttggt gagaattacc atacggataa
    11821 tttggttgga tttgcctggt cttgtgggga taagctctat gccacagaca agcttgagct
    11881 gttgcaagac ccgattttca aggatttctt agaaaaaaca tctctgagag tttatgactt
    11941 taagaaggtt aaagttcttt tgcaacgttt tggtgtggat ttgcaggcgc ctgcttttga
    12001 catccgtttg gctaaatacc tcctttcgac tgtggaggac aatgaaattg cgaccatcgc
    12061 tagtctttat ggtcagactt acttggttga tgatgaaact ttctacggta agggtgttaa
    12121 aaaggccatt cctgaacgtg agaaattctt ggaacactta gcttgtaaac ttgctgtttt
    12181 ggtaggaaca gagcctattt tacttgaaaa actcagcgaa aatgggcaat tagagcttct
    12241 ttatgatatg gagcaacctc tggcttttgt tcttgccaag atggaaattg ctgggattgt
    12301 ggtcaagaaa gagaccttgc ttgagatgca ggctgaaaat gagcttgtca ttgaaaaact
    12361 gactcaagag atttacgagc tggctggtga ggagtttaat gtcaactcgc ctaagcagtt
    12421 gggcgtgctt ctctttgaga aattgggact tcctctagaa tacactaaga aaaccaagac
    12481 aggttattcg acagcagtgg atgtgttgga gcgtctcgct cctattgctc cgattgttaa
    12541 gaaaatcctg gattaccgtc aaattgctaa gattcaatct acttatgtaa ttggcttgca
    12601 ggactggatt ttggctgatg gaaagattca tactcgctat atgcaggatt tgacccagac
    12661 cgggcgtttg tctagtgtgg atccaaactt gcaaaatatt cctgctcgat tggaacaagg
    12721 gcgcttgatt cggaaggctt ttgtgccaga gtgggaggat agtgtgctac tcagctctga
    12781 ctattcacag attgaattgc gcgttttggc gcatatttct aaggatgagc acttgattaa
    12841 ggccttccaa gagggggcag atatccatac ttcgacagcc atgcgggtct ttggcattga
    12901 gcgtcctgat aatgtgactg caaatgaccg tcgcaatgcc aaggcagtta actttggagt
    12961 ggtttatggg atttcagact ttggcttgtc taataatttg ggaattagtc gtaaggaagc
    13021 caaagcctac attgatacct actttgaacg ttttccaggt attaaaaact acatggatga
    13081 agtggtgcgg gaggcgcgtg ataagggcta tgtagagacc ctctttaagc gtcgccgtga
    13141 gttgccagat atcaattcgc gcaacttcaa tattcgtggt tttgcggagc gaactgctat
    13201 caactcacct atccagggtt cggcagcaga tattctcaag attgccatga ttcagctgga
    13261 taaagccttg gttgcaggtg gttatcagac taagatgctg ttacaagtgc acgatgaaat
    13321 cgtccttgaa gtgcctaaat ctgaattggt agagatgaaa aaattggtga aacaaaccat
    13381 ggaagaagcc attcaactca gtgttcctct tatcgcagat gagaatgaag gggcaacctg
    13441 gtacgaggct aaataaaaag ggggctagtc ctcctttttt gtagtagaat tctgcaaacc
    13501 ttttcaaaat gtgctatact gatgaaaaag gaggatttct atgagtcaag aatttatcaa
    13561 tccaagtgat ggcgtgattc gtcagtatct cgcaacgagt aaaacccttg ctgtggtggg
    13621 tttgtctgac cgtgaagaaa caactagcaa tcgagtaaca aaggaaatgc aggctcgggg
    13681 ctataaaatc atcccagtca atcccaaggc ggcaggtggc gaaatcttgg gtgaaaaggc
    13741 ttatgctagc ctcgctgaaa ttccttttcc tgtagatatt gtcaatgttt atcgtcgcag
    13801 tgaatttctg cccgatgtgg cgcgtgattt tctcaaagct gatgccaaga ttttttgggc
    13861 acagctagga cttgaaagtt tagaagcgaa agagattttg cgtgatggtg gatgtgatga
    13921 tatcgtgatg aatcgctgta tcaagagaga acatactcgc ttgattgagg aagcataaga
    13981 aaaaggtagc tgatgggcta ccttttgtgt tatactcaat gaaaatcaaa gagcaaacta
    14041 gcaaactagg aaactagccg cgggctgctc aaaacactgt tttgaggttg tagatagaac
    14101 tgacgaagtc agctcaaaac accgttttga ggttgcagat agaactgacg aagtcagtaa
    14161 catatatacg gcaaggcgac gttgacgtgg tttgaagaga ttttcgaaga gtattagaaa
    14221 atgccgataa gggtctgcat accaagagtg gtgaggatga tggcaatcca gcagatggct
    14281 ccgagaacaa tggattttcc actggatttg accatagcga ccagattggt tttgagaccg
    14341 atagcactca tggccatgac aatgaggaat ttagagagtt gtttgagagg ggtaaagaaa
    14401 ctactagaca caccgagaga ggtcagaagg gtggttagga gcgatgcaag gataaagtaa
    14461 aggataaaaa gtgggaagac ttttttcagt tgtaggcttt gcttgttttc ttgttggcga
    14521 ctttgccagt aggatagaaa gagcgtgata gggataatgg ccaaagtacg tgtgagttta
    14581 acaatggttg cagactcgag ggtattgctt tggtaaagac tgtcccaagc gctggcggca
    14641 gccgttacag aggaagtgtc gttgaccgca gtccctgcaa agagggcgaa gccttcattg
    14701 gatagatgaa gccaggtgcc gagggttgga aagatgagcg cagccaagac attgaagaaa
    14761 aagataacgg aaatggcttg ggctacttcc ttttccttag catcaataac gggcgctgtc
    14821 gctgcaatgg cagaaccccc acagatagaa gaacctactc caaccaaggt agccagtttt
    14881 gtatccagtg caaagaaacg ctggaagagg taggcaataa tcagagctat tgagatagtg
    14941 gacaggatga cagggagtga agattggcca actgcgaaga cctgcgagat attgagacca
    15001 aaaccaagca agacaacggc atattggagc aacttcttgg aactaaaggt caaaccagca
    15061 tccagttgtt tataggacga gagaaaggga tgtaggagca tgcctatgaa aatggcaaaa
    15121 acgggcgcgc caatcacagg gaagaatcct cctaagtacc aagataggat ggaaatgaga
    15181 aggcaggcca agatacctgc tccatttttt gatagaaatg acataaaaac ctccaaataa
    15241 aatctattac cattatagac ctataaacag gaaaagtaaa atagaaagtg gaaagctatt
    15301 ctctaatgta tttttgcggt cggggggctt ttgtagtata atagagatac gttttgaaag
    15361 taggaggtat ctatggactt aactaagcgc tttaataaac agttagataa aattcaagtt
    15421 tcgttgattc gtcagtttga ccaggctatt tcggagattc ctggggtctt gcgtttgacc
    15481 ttgggggaac ctgattttac aacgccagac catgtcaagg aggcggccaa gcgagcgatt
    15541 gatcagaacc aatcctacta tacagggatg agtggtctgc tgactctacg tcaggcagcc
    15601 agtgactttg ttaaggaaaa gtaccaactg gactatgctc ctgaaaatga aatcttggtt
    15661 acaattgggg cgacagaggc tttatctgcg actttgacgg ctattttgga agagggagac
    15721 aaggtacttt tgccagctcc tgcttatcca ggctatgaac cgattgttaa cttagttggg
    15781 gcagaaattg ttgagattga tacgactgaa aatggttttg tcttgactcc tgagatgttg
    15841 gagaaggcca ttttggagca gggtgataag ctcaaagcgg ttattctcaa ctatccagcc
    15901 aatccgacag gaattaccta cagtcgagag cagttagagg ccttggcagc tgttttacgc
    15961 aagtacgaag tttttgttgt ctgtgatgag gtttactcag aattgaccta cacaggcgaa
    16021 gcccatgtgt ctctaggaac gatgttgaga gaccaggcta ttattatcaa tggtttgtct
    16081 aaatcgcatg ccatgacagg ttggcgtttg gggctgattt tcgctccggc gaccttcaca
    16141 gcccagttaa tcaagagtca ccagtacttg gtcactgccg caaataccat ggcgcaacat
    16201 gctgcggtag aagccttgac ggctggtaaa aatgatgcgg agcccatgaa gaaggaatat
    16261 atccagcgtc gggactatat catcgaaaaa atgactgctc ttggttttga gattatcaaa
    16321 ccagacggtg ccttctatat ttttgctaaa attccagcgg gctacaatca agactccttt
    16381 gcttttctga aggattttgc tcagaagaag gccgttgcct ttatccctgg tgcagccttt
    16441 ggacgttacg gggaaggcta cgtccgccta tcttatgcag ccagcatgga gactatcaaa
    16501 gaagccatga aacgacttga ggagtacatg agagaagcat gattcagtct atcacgagtc
    16561 aaggcttggt gctttacaat cgcaattttc gtgaggatga caagctcgtc aaaattttta
    16621 cagagcaggt tggcaaatgc atgttttttg tcaaacacgc tggtcagtct aagctggcgc
    16681 ctgttattca gcccttggtg ctggcacgat ttctcttgcg aatcaatgat gacggactca
    16741 gttacatcga agactatcat gaggtcatga cttttcccaa gattaatagt gacctctttg
    16801 tcatggccta tgcgacctat gtggcagctc ttgcagatgc tagtttgcag gacaatcagc
    16861 aggatgctcc cttgtttgct tttttgcaaa agactttgga gttgatggaa gcaggcttgg
    16921 attatcaggt tttgaccaat atttttgaaa ttcaaatttt gactcgattt ggaatcagcc
    16981 tcaattttaa tgagtgtgtc ttctgccatc gggttggtca ggcttttgac ttttctttca
    17041 aatatggagc ctgcctctgt ccagagcatt atcatgagga taagagacgt tgtcatctca
    17101 atcccaatat cccctatctg ctcaatcaat ttcaagctat tgattttgag actttggaga
    17161 ccatttcgct caagcctgga atcaagcaag agctacgcca atttatggat caattatatg
    17221 aagagtacgt tgggattcac ctaaaatcaa agaaatttat tgattcccta gcagactggg
    17281 gacaattact aaaagaggaa aagaaatgaa aaaaatcgca gtagatgcca tggggggcga
    17341 ttacgcacct caggccattg ttgagggtgt caatcaagcc ctatctgact tttcagatat
    17401 cgaggttcaa ctttacggag atgaagctaa aatcaagcaa tatctgacag cgacagagcg
    17461 cgtcagcatt atccatacgg atgagaagat tgattcggat gatgaaccta cgagagctat
    17521 taggaataag aaaaatgcca gtatggtatt ggcagccaag gctgtcaaag atggtgaagc
    17581 agacgctgtc ctttcggctg ggaatacagg tgccttgttg gcagcaggat tcttcatcgt
    17641 gggtcgtatc aagaatatcg accgtcctgg actcatgtct accttgccta ccgttgatgg
    17701 aaaaggtttt gacatgctag accttggtgc caatgcagaa aatacagccc agcacctcca
    17761 tcaatatgcg gttctaggtt ccttctatgc taaaaatgtc cgtggcattg cgcaaccacg
    17821 cgttggtttg ctcaacaacg gaacagagag tagcaagggc gacccgcttc gtaaggaaac
    17881 ttatgaatta ctggcggctg atgaaagttt gaactttatc ggaaacgtgg aagcgcgtga
    17941 tttgatgaat ggcgttgcag atgttgttgt ggcagatggt ttcacgggaa acgctgtgct
    18001 caaatccatc gaagggacag ctatgggaat catgggcttg ctcaagacag ctattacagg
    18061 tggtggtctt cgagcgaaac taggtgccct ccttctcaag gacagcctca gaggtttgaa
    18121 aaaacagctc aattattcag atgttggtgg agcggtcttg tttggtgtta aggcacctgt
    18181 tgtcaagact catggctcaa gcgatgccaa ggctgtttat agtacgattc gccagattcg
    18241 taccatgcta gaaacagacg tagttgccca gactgcgcgt gaattttcag gagaataaaa
    18301 gagatgacag aaaaagaaat ttttgaccgt attgtgacca ttatccaaga gcgacaggga
    18361 gaggactttg tcgtgacaga atccttgagt ctgaaagacg atttggatgc ggattctgtt
    18421 gacttgatgg agtttatctt gaccctggaa gatgaattta gtatcgaaat cagcgatgaa
    18481 gaaattgacc aactccaaaa cgtaggagat gtggttaaaa tcattcaagg aaaatagcaa
    18541 tcggagttcc aagtcaacgg aagtagatgg tttttagaaa tgagaaatat cggacaagct
    18601 ggtaaaatct tggctgacag tggttatcaa gggctcatga agatatatcc tcaagcacaa
    18661 actccacgta aatccagcaa actcaagccg ctaacagttg aagataaagc ctgtaatcat
    18721 gcgctatcta aggagagaag caaggttgag aatatctttg ccaaagtaaa aacgtttaaa
    18781 atgttttcaa caacctatcg aaatcatcgt aaacgcttcg gattacgaat gaatttgatt
    18841 gctggtatta tcaatcatga actaggattc tagttttgca ggaagtctaa tagtaaaaaa
    18901 gtgattagaa aacatctttt ttaaaaatag agatgatttt gaaacaaaaa agctaattca
    18961 agacgtttcg atgccaattc aagatttgga tgaaaaaaat taatagatac tgttatacta
    19021 aacttgtcaa gtttgtaaca agacaaatat taaaaataaa aaagaggtat tcgttatgaa
    19081 tacaaaaacg atgtcacaat ttgaaattat ggatactgag atgcttgctt gcgttgaagg
    19141 tggcggatgc aattggggag attttgccaa agcaggtgtt ggaggaggag cagtacgagg
    19201 tcttcagcta ggaattaaaa caagaacatg gcaaggtgca gcaactggtg ctgcgggagg
    19261 agctatactt ggaggtgtgg cctatgcagc gacatgttgg tggtaattat ggattttaaa
    19321 agttttatta ttggtttagt agttggtata tttggtcctt atatggatga tttaattaga
    19381 aaaaaatttt taaagtcttc ggagaagaaa acagaaaaat ctgttaaaaa ataatcaaaa
    19441 ctataaatga tgaatctgaa tcaaaattat tttgcgcatg taaagaggag tcttatagta
    19501 acgagtcaaa aaaggagtaa ctatgaatcg taatttagaa cggtgttatc tattctgact
    19561 aggaatagat cataccagag gtagcttaga aatagcaggg acattagaaa ttgaagtaat
    19621 aaataggatg tcgtaagtgt tactatcaat gatttatttg tttcaagctt gcctagggtg
    19681 acagtaaaaa atcaatttcc tttcaatagc atatttttag tgggcaggac tcttgttctg
    19741 cctatttttt tatccaaaaa gtgcagttgg gagggagata ggctcatttg ggaaggaagt
    19801 ccagtttttg tttagtgatt ggggtaagat agttgttatc agatgagttt atactcttcg
    19861 aaaatcaaat tcaaaccacg tcaacgtcgc cttgccgtat atatgtgact gacttcgtca
    19921 gtcctatcta caacctcaaa acagtgtttt gagcagcctg cggctagttt cctagtttgc
    19981 tctttgattt tcattgagta ttagggaaaa ggagatgaat atgaaatttg ggaaacgtca
    20041 ctatcgtccg caagtggatc agatggactg cggtgtagct tcattagcca tggtttttgg
    20101 ctactatggt agttattatt ttttggctca cttgcgagaa ttggctaaga cgaccatgga
    20161 tgggacgacg gctttgggct tggtcaaggt ggcagaggag attggttttg agacgcgagc
    20221 cattaaggcg gatatgacgc tttttgactt gccggatttg acttttcctt ttgttgccca
    20281 tgtgcttaag gaagggaaat tgctccacta ctatgtggtg actgggcagg ataaggatag
    20341 cattcatatt gccgatccag atcccggggt gaagttgact aaactgccac gtgagcgttt
    20401 tgaggaagaa tggacaggag tgactctttt tatggcacct agtccagact ataagcctta
    20461 taaggaacaa aaaaatggtc tgctctcttt tatccctata ttagtgaagc agcgtggctt
    20521 gattgccaat atcgttttgg caacactctt ggtaaccggg attaacattg tgggttctta
    20581 ttatctgcag tctatcattg atacctatgt gccagatcag atgcgttcga cactagggat
    20641 tatttctatt gggctagtca tcgtctacat cctccagcaa atcttgtctt acgctcagga
    20701 gtatctcttg cttgttttgg ggcaacgctt gtcgattgac gtgattttgt cctatatcaa
    20761 gcatgttttt cacctcccta tgtccttctt tgcgacacgc aggacagggg agatcgtgtc
    20821 tcgttttaca gatgctaaca gtatcatcga tgcgctggct tcgaccatcc tttcgatttt
    20881 cctagatgtg tcaacggttg tcattatttc ccttgttcta ttttcacaaa ataccaatct
    20941 ctttttcatg actttattgg cgcttcctat ctacacagtg attatctttg cctttatgaa
    21001 gccgtttgaa aagatgaatc gggataccat ggaagccaat gcggttctgt cttcttctat
    21061 cattgaggac atcaacggta ttgagactat caagtccttg accagtgaaa gtcagcgtta
    21121 ccaaaaaatt gacaaggaat ttgtggatta tctgaagaaa tcctttacct atagtcgagc
    21181 agagagtcag caaaaggctc tgaaaaaggt tgcccatctc ttgcttaatg tcggcattct
    21241 ctggatgggg gctgttctgg tcatggatgg caagatgagt ttggggcagt tgattaccta
    21301 taataccttg ctggtttact ttaccaatcc tttggaaaat atcatcaatc tgcaaaccaa
    21361 gcttcagaca gcgcaggttg ccaataaccg tctaaatgaa gtgtatctag tagcttctga
    21421 gtttgaggag aagaaaacag ttgaggattt gagcttgatg aagggagata tgaccttcaa
    21481 gcaggttcat tacaagtatg gctatggtcg agacgtcttg tcggatatca atttaaccgt
    21541 tccccaaggg tctaaggtgg cttttgtggg gatttcaggg tcaggtaaga cgactttggc
    21601 caagatgatg gttaattttt acgacccaag tcaaggggag attagtctgg gtggtgtcaa
    21661 tctcaatcag attgataaaa aagccctgcg ccagtacatc aactatctgc ctcaacagcc
    21721 ctatgtcttt aacggaacga ttttggagaa tcttcttttg ggagccaagg aggggacgac
    21781 acaggaagat atcttacggg cggtcgaatt ggcagagatt cgagaggata tcgagcgcat
    21841 gccactgaat tatcagacag aattgacttc ggatggggca gggatttcag gtggtcaacg
    21901 tcagagaatc gctttggcgc gtgctctctt gacagatgcg ccggtcttga ttttggatga
    21961 ggcgactagc agtttggata ttttgacaga gaagcggatt gtcgataatc tcatggcttt
    22021 ggacaagacc ttgattttca ttgctcaccg cttgactatt gctgagcgga cagagaaggt
    22081 agttgtcttg gatcagggca agattgtcga agaaggaaag catgctgatt tgcttgcaca
    22141 gggtggcttt tacgcccatt tggtcaatag ctagaaagag gagaggatga aaccagaatt
    22201 tttagaaagt gcggagtttt ataatcgtcg ttaccataat ttttccagta gtgtgattgt
    22261 acccatggcc cttctgcttg tgtttttact tggctttgca actgttgcag agaaggagat
    22321 gagtttgtcc actagagcta ctgtcgaacc tagtcgtatc cttgcaaata tccagtcaac
    22381 tagcaacaat cgtattcttg tcaatcattt ggaagaaaat aagctggtta agaaggggga
    22441 tcttttggtt caataccaag aaggggcaga gggtgtccaa gcggagtcct atgccagtca
    22501 gttggacatg ctaaaggatc aaaaaaagca attggagtat ctgcaaaaga gcctgcaaga
    22561 aggggagaac cactttccag aggaggataa gtttggctac caagccacct ttcgcgacta
    22621 catcagtcaa gcaggcagtc ttagggctag tacatcgcaa caaaatgaga ccatcgcgtc
    22681 ccagaatgca gcagctagcc aaacccaagc cgaaatcggc aacctcatca gtcaaacaga
    22741 ggctaaaatt cgcgattacc agacagctaa gtcagctatt gaaacaggtg cttccttggc
    22801 cggtcagaat ctagcctact ctctttacca gtcctacaag tctcagggcg aggaaaatcc
    22861 ccaaactaag gttcaggcag ttgcacaggt tgaagcacag atttctcagt tagaatctag
    22921 tcttgctact taccgtgtcc agtatgcagg ttcaggtacc cagcaagcct atgcgtcagg
    22981 gttaagcagt caattggaat cccttaaatc ccaacacttg gcaaaggttg gtcaggaatt
    23041 gacccttcta gcccagaaaa ttttggaggc agagtcaggt aagaaggtac agggaaatct
    23101 tttagacaag gggaaagtta cggcgagtga ggatggggtg cttcatctta atcctgagac
    23161 cagtgattct agcatggttg cagaaggtgc cctactagcc caactttatc catctttgga
    23221 aagagaaggg aaagccaaac tcacagctta tctaagttca aaatatgtag caagaatcaa
    23281 ggtcggtgat tctgttcgct atactacgac tcatgatgcc gggaatcaac ttttcctaga
    23341 ttctactatt acaagtattg atgcgacagc tactaagact gagaaaggga atttctttaa
    23401 aatcgaggcg gagactaatc taacttcgga gcaggctgaa aaacttaggt acggggtgga
    23461 aggccgcttg cagatgatta cgggcaagaa aagttaccta cgttattatt tggatcaatt
    23521 tttgaacaaa gagtaatgtt cgtgttttta gagttaaata atttttaaac tgtgagaaag
    23581 attcttcttg cagttttttc tttacaattt ttgaaaaaca tctactattt attcggttaa
    23641 attcttgtgt tttttggttt tttgtggtaa aatgtgctca agtaatacga aaggcgaact
    23701 ttaaaatgtc aaaacaattg atctattcgg gaaaagctaa agatatctat acaactgagg
    23761 atgaaaatct tattatttca acttacaagg accaggcgac tgctttcaac ggtgtcaaga
    23821 aggagcagat tgcaggtaag ggagtcttga ataatcagat ctcatctttt atttttgaga
    23881 aattaaatgt ggctggtgtg gcgactcact ttgtggagaa actttcagac acggaacaac
    23941 tcaataaaaa ggttaagatt attcctttgg aagtcgtgct ccgcaactat actgctggtt
    24001 ccttttcaaa acgttttggt gtggatgagg gaatcgcctt ggagactccg attgtcgaat
    24061 tttactacaa aaatgatgat ttggatgatc catttatcaa tgatgagcat gtgaaattcc
    24121 tacagattgc gggtgaccag cagattgcct acttgaagga agaaacgcgt cgtatcaatg
    24181 aactattgaa agtctggttt gctgagattg ggcttaaatt gattgacttt aagctagagt
    24241 tcggttttga caaggatggc aagattatct tggcagacga attttcacca gataactgcc
    24301 gcttgtggga cgctgatggc aaccacatgg ataaggatgt tttccgtaga ggattgggag
    24361 aactaaccga cgtttatgag attgtttggg aaaagttgca ggaattgaaa taatctgttt
    24421 gcaacggaaa accttcgtct ctcaactaaa aggactcagg ctgaaaaggt cccccagacc
    24481 ttttcactct gtagagaact aggtgaacta acagatgttt acgaaattgt ctgggaaaag
    24541 ttgcagggtt taaaataaca acctcaaggc tgtttgggaa tattgcaaga gctgaaataa
    24601 aggaataaga attgatggat aaacgtattt ttgttgaaaa aaaggctgat tttcaggtca
    24661 agtcagagag tttggttaga gagctccagc acaacttggg actgtcaagc ttgaaaagta
    24721 ttcgtattgt gcaagtatat gatgtatttg acttggctga ggacttgttt gcacctgcag
    24781 agaagcacat tttctctgag cagggaaccg accatgtttt agatgaagta tctgtgcagg
    24841 cggatcttgc taactatgct ttctttgcca ttgaaagtct gccagggcag tttgaccagc
    24901 gtgcagcttc gtcacaggaa gccttgcttt tgttgggaag ttcgagtgac gtgacagtca
    24961 acacagccca actttacttg gtgaataaag atattgatgc gactgagttg gaagctgtca
    25021 aaaactacct gctcaatcca gttgattctc gtttcaagga tatcacgaca gggattgcca
    25081 agcaggagtt ttcagagtca gacaagacca ttccaaaatt gactttcttt gaaagctata
    25141 cagcagaaga ctttgctcgc tacaaggccg agcaagggat ggccatggaa gtggatgatt
    25201 tgctctttat ccaagactac tttaagtcaa tcgggcgcgt gccaactgag actgaactca
    25261 aggttttgga cacttactgg tctgaccact gccgtcatac gacttttgag acagagttga
    25321 aacacatcga cttttcagct tctaaatttc aaaagcaatt gcagtcaacc tatgacaagt
    25381 atattgccat gcgcgaggag ttaggtcggt ctgaaaaacc acaaaccttg atggatatgg
    25441 cgactatttt cggtcgttat gagcgtgcta acggacgatt ggatgatatg gaagtctctg
    25501 acgaaatcaa tgcctgctca gttgaaattg aagtggatgt tgatggtgtc aaggaacctt
    25561 ggctcctcat gtttaaaaat gaaacccaca accatccaac agaaattgag ccatttggtg
    25621 gagcggctac ctgtatcggt ggagctattc gtgatccgtt gtcaggccgt tcctatgttt
    25681 accaagccat gcgtatttca ggtgctggtg atattacagc accgatttcg gaaactcgtg
    25741 ctgggaaatt gccacaacaa gtcatttcta aaacagcagc tcatggttat tcttcatatg
    25801 gtaaccagat tgggcttgcc acaacctacg ttcgtgaata cttccaccca ggctttgtag
    25861 ctaaacgtat ggaacttggt gccgttgttg gtgcggctcc caagggcaat gttgtccgtg
    25921 aaaaacctga agcaggtgat gtgatcatcc ttctcggagg caaaacaggt cgtgatggtg
    25981 tcggtggtgc gacgggctct tctaaggttc aaacagttga gtctgtagag actgctggtg
    26041 ctgaggttca aaaaggaaat gccatcgaag aacgcaagat tcagcgcctc ttccgtaatg
    26101 gcaatgtcac tcgtctgatc aagaagtcca atgactttgg ggcaggcggc gtctgtgtgg
    26161 ctatcggtga attggcagac ggtcttgaaa tcgacctcaa caaggtgcct cttaaatacc
    26221 agggcttgaa tggtacagaa attgccatct ctgaatcaca agaacggatg gcggtcgtgg
    26281 ttcgtcctga agatgtggat accttcgttg ccgaatgtaa caaagaaaat attgatgctg
    26341 ttgtggtggc gacagtaact gaaaaaccaa atcttgtcat gcactggaat ggtgagacaa
    26401 tcgttgactt ggagcgtcgt ttccttgaca ccaatggtgt gcgcgtggtt gtcgatgcca
    26461 aagttgtgga caaggatgtc aaactcccag aagagcgtca aacatctgct gaaacactgg
    26521 aatcagatac ccttacggtt ctatctgacc tcaaccatgc aagtcaaaaa ggattacaga
    26581 ctatctttga ctgctctgtt ggacgctcaa cggttaatca cccacttggt ggtcgttacc
    26641 aactcacacc aactgaggca tctgtgcaga aattgccagt tcaacacggt gtgactcata
    26701 ctgcgtcggt cattgctcaa ggtttcaacc catatgtagc tgaatggtct ccataccacg
    26761 gtgctgctta tgcggttatc gaagcaactg ctcgtttggt ggctgctggt gccaactggt
    26821 ctaaggctcg tttctcttac caagaatatt tcgagcggat ggacaagcaa gcagagcgtt
    26881 tcggtcagcc agtagctgct cttctaggtt ctattgaagc acaaattcag cttggcttgc
    26941 catctatcgg tggtaaggac tccatgtctg gtacctttga agaattgacc gttccgccaa
    27001 ccttggttgc ctttggggtg acgacggcag atagccgtaa ggtgctctct ccagaattta
    27061 aagctgttgg ggaaaatatc tactacatcc caggtcaagc cctctctgca gagattgatt
    27121 ttgacttgat taagaaaaat tttgctcagt ttgaagcaag ccaagctgac cataaagtga
    27181 cgtctgcatc agctgtcaaa tacggtggtg tagttgaaag tttggctctt gctacctttg
    27241 gaaactatat tggtgcagag gtgaccttgc ctgaacttaa aacagctttg acagctcaat
    27301 taggcggctt tgtcttcaca tctcctgaag aaattgctgg agtagagaag attggacaaa
    27361 cgaaagcaga ctttacactg actgtcaacg gtgtgaagct agatggacac aagcttgaca
    27421 gtgcatttca agggacattg gaagaagttt acccaacaga atttacccaa gcgaaagaac
    27481 tagaagaagt accagctgtg gcatcagatg ttgtgattaa agccaaagaa aaggttgaaa
    27541 aacctgtggt ttacatccca gtctttccag gaaccaactc agaatatgat tcagctaagg
    27601 ccttcgaaaa agaaggtgca gaggtcaatt tggtgccatt cgtgaccttg aatgaagaag
    27661 ctattgtcaa gtcagttgaa actatggttg acaatatcga caagactaat attctcttct
    27721 ttgccggtgg attctcggct gcggatgaac cagatggttc agctaagttt atcgtcaata
    27781 tcctgcttaa tgaaaaagtg cgtgtggcta ttgatagctt tatcgcccgt ggtggcttga
    27841 ttatcggtat ttgtaatgga ttccaagcct tagtcaaatc gggtctccta ccatacggaa
    27901 actttgaaga tgctaacagt actagtccaa ccctcttcta caatgatgcc aaccaacacg
    27961 tggccaagat ggtggaaact cgtattgcca ataccaactc accatggttg gctggtgtgc
    28021 aagtgggcga tatccacgct attcctgttt cgcacggtga agggaagttt gtcgtgacgg
    28081 ctgaggaatt tgcagagctc cgtgacaatg gacaaatttt cagccaatac gttgacttta
    28141 acggtaaacc aagtatggat tctaagtaca atccgaatgg ttctgtccat gccatcgaag
    28201 gaattaccag caagaatggt caaatcatcg gtaagatggg ccactcagaa cgttatgagg
    28261 atggtctttt ccaaaatatc ccaggcaata aagaccaaca cctgttcgca tcagcggtta
    28321 aacatttcac tggaaaataa gacttacaga ttttctaata gatagtatca gtaatgtaaa
    28381 agtcatgtaa atctagctct tgatgattac aaatgaaaat taggtataaa aaatgacata
    28441 cgaagtaaaa tctcttaatg aagaatgtgg tgttttcggt atttggggac atccagatgc
    28501 tgctaagttg acctattttg gactccacag tcttcaacac cgtggtcagg agggggcagg
    28561 aatcctctcc aatgatcaag gacaactgaa gcgccatcgt gacatggggc ttttatcaga
    28621 agttttcaga aatccagcca atttggataa attgacagga gctggtgcga ttgggcatgt
    28681 gcgttatgcg actgctggcg aagcttctgt tgataacatc caacccttcc tcttccgttt
    28741 tcacgatatg cagtttggtt tggctcataa tggaaatctg accaatgcag cctctctcaa
    28801 gaaagaactg gaacaaagag gagcaatttt cagcgcgact tcggactctg aaatcttggc
    28861 tcacctcatt cgtcgcagtc ataatcctag cctgatgggc aaaatcaagg aagcgctcag
    28921 ccttgtcaaa ggtggttttg cctatatctt gctgtttgag gacaagttga ttgcggctct
    28981 tgaccctaat ggctttcgtc cgctttctat cgggaaaatg gccaacggag cggtggttgt
    29041 ttcctctgaa acctgtgctt ttgaggtcat tggtgtcgag tggatttgtg atttgaagcc
    29101 aggtgagatt gtgatcattg atgacgaggg cattcagtat gacagctata cagatgatac
    29161 ccagttggcg atttgttcta tggagtatat ctactttgcc cgccctgatt ctaatatcca
    29221 cggtgtcaat gtccatacgg cacgtaagag aatgggagcg caattggcgc gagaatttaa
    29281 gcatgaggca gatattgtag ttggtgtgcc caattcttcc ctaagcgcgg ctatgggatt
    29341 tgcggaagaa tcaggcttac caaatgaaat gggtctgatc aaaaaccaat acacccagcg
    29401 aacttttatc caaccgactc aagaattgcg ggagcaagga gtgcggatga aactgtctgc
    29461 tgtttcgggt gttgtcaaag gcaaacgtgt ggtcatggtg gatgattcca ttgtacgtgg
    29521 aacaacctct cgtcgtatcg ttcagctctt gaaagaagcg ggtgcgactg aggttcacgt
    29581 tgccattgga agtcctgcac tagcgtatcc atgtttctac gggattgata tccagacccg
    29641 tcaggagctg attgcagcca atcatacggt cgaagaaact cgccaaatca ttggtgcgga
    29701 cagtctgact tatctttcaa ttgatggctt gattgagtcg attggtatcg aaacagatgc
    29761 gccgaacggt ggtctctgtg tcgcttactt tgacggtgac tacccaacgc ctctctatga
    29821 ctacgaagaa gactatcgta gaagtttgga agaaaagacc agtttttaca agtaggcgac
    29881 agattctcca ttaaagaaaa ggaaaaaaca aatgacaaat aaaaatgcat atgcctcacg
    29941 tctcactact gactaaaggc ttaagcattt agtcagtaga cgctttgtcc tataggatca
    30001 aagctagagc cctgactagt atttttagat aaaaagatgg tttatctaaa aatacgtcgc
    30061 agtctttctc aaaaaaagaa aaggaaaaat aaaatggcaa ataaaaatgc gtacgctcaa
    30121 tctggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa gcacgtggct
    30181 cgtacggagc gtgcaggtgt catgggagct cttggtggct ttggtggtat gtttgacctt
    30241 tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt cggaaccaag
    30301 ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg tgtggccatg
    30361 tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga ctacgtagcg
    30421 acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtagc agaaggttgt
    30481 gtgcaggctg gtgctgccct catcgctggg gaaacggctg aaatgccggg catgtacggc
    30541 gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc tcaaatcatt
    30601 gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgcttcaag tgggattcac
    30661 tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga ggaagtccta
    30721 ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg tatctatgtc
    30781 aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca catcacaggt
    30841 ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc tgaaattgat
    30901 gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg tcagattaaa
    30961 cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc ggtcagccct
    31021 gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat tggtcgcatc
    31081 gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt tttgcctctg
    31141 gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt gtcttttcag
    31201 accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg tcctatgctt
    31261 ttgaactcaa ggagtttgag agcaagacag actacgaagc agcccttgtc gaactcttgg
    31321 aagaacacca gattgacttg gtttgcctag caggctacat gaaaatcgtt ggaccaacct
    31381 tattgtcggc ttatgaaggt cggattgtca acattcatcc agcctacttg ccagaatttc
    31441 caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct ggtgtgacca
    31501 ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt cgtgtgccac
    31561 gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca gagtacaggt
    31621 tgtatccgga agtagtgaag gctctattta cagattgact ttttgatgat tcatatgata
    31681 tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg aggtatttgt
    31741 aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga tgttattaac
    31801 ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt tcttagctcc
    31861 aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa aaattgtttt
    31921 tgctgaaatg ttatttaatc tgatttcctt tattccatta ggtgtttgtt tccctttgat
    31981 aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta gtttattgtt
    32041 tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt tgactttaaa
    32101 tacgctaggt gtctgtgtag gcttactgat ttatcaaatt tttataagag tgttcaaatc
    32161 acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg cttatcttgt
    32221 tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga atataatgac
    32281 taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg cccaagaact
    32341 aaaaaaactt ggttgggaga ttatctcgac aggtggaact aaggttgccc ttgataatgc
    32401 tggggtggag accattgcga tcgatgatgt gacgggcttc ccagagatga tggatggccg
    32461 tgttaagact cttcatccaa atatccacgg gggtcttctc gctcgtcgtg atttggatag
    32521 ccacttggaa gcagccaatg agaaccaaat tgagcttatt gaccttgtag tggtcaacct
    32581 ttacccattt aaggaaacta tccttaaacc agatgtgact tatgctgatg cagttgaaaa
    32641 tatcgatatt ggtgggccgt ctatgcttcg ttcagcagcg aaaaatcatg ccagtgttac
    32701 agttgtggta gatcctgctg actacgctgt ggttttggac gaattggcag caaacggcga
    32761 aacctcttat gaaactcgcc aacgtttagc agccaaagta tttcgtcaca cagcggctta
    32821 tgacgccttg attgcagaat acttcacagc tcaagtgggt gaaagcaagc ctgaaaaact
    32881 cactttgact tatgacctca agcaaccaat gcgttacggt gagaatcctc aacaagacgc
    32941 ggacttttac cagaaagctt tgcctacaga ttactctatt gcttcagcca aacagctcaa
    33001 cgggaaagaa ttgtcattta ataatatccg tgatgcagat gctgctatcc gtatcatccg
    33061 tgacttcaaa gatagtccaa ccgttgtggc tctcaagcat atgaatccat gtggtatcgg
    33121 ccaggcggat gacatcgaga cggcttggga ttatgcttat gagtctgacc cagtgtctat
    33181 ctttggtggt atcgttgttc ttaaccgtga ggtggatgct gcgacagctg agaagatgca
    33241 cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc tagctatttt
    33301 gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc aagaggctag
    33361 cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa atcaagacgt
    33421 ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa ccgagacaga
    33481 agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa atggtattat
    33541 cgtgaccaac gatcacatga cacttggtgt tggtccaggt caaaccaacc gtgtggcttc
    33601 tgttcgcctt gccattgacc aagccaaaga tcgtctggac ggggcggtcc ttgcttcaga
    33661 tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa ttaaggccat
    33721 catccagccc ggtggctctg tccgtgacca agaatccatc gaagcagcgg ataaatatgg
    33781 cttgactatg gtctttacag gtgtgagaca ttttagacat taagaagata aaagggaaga
    33841 aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta aaacgaactt
    33901 ttttgatata atgttggtaa ataattcgca aaagaggttg aggaatgaaa ctgcttgttg
    33961 tcggttctgg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca aaagacgtgg
    34021 aaaaagtctt tgtagctcct gggaatgatg ggatgactct ggatggtttg gaattggtaa
    34081 atatctctat ttccgaacat tctaaattga ttgacttcgc aaagaccaat gatgttgctt
    34141 ggacctttat cggtccagat gatgcccttg ctgctggtat cgtggatgat tttaaccaag
    34201 ctggacttaa ggcctttggt ccgactaggg ctgcagcgga gctggagtgg tccaaggatt
    34261 tcgccaagga aatcatggtc aaatacggcg ttccgacagc aacatatggc acattttcag
    34321 atttcgagga agccaaggcc tatatcgaaa agcatggtgc gcctatcgta gtcaaggcgg
    34381 atggcttggc acttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa gcggtcgaag
    34441 ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc gtggttattg
    34501 aggaattcct tgaaggagag gaattttcac tctttgcctt tgtcaatggt gataagttct
    34561 acatcatgcc aacggctcag gaccacaaac gtgcctatga tggcgacaaa gggcctaaca
    34621 cgggtggtat gggtgcctat gcgccagtcc cacacttacc acagagtgta gttgatacag
    34681 cggttgacac cattgtcaag ccagttctag aaggggtgat taaagaaggt cgcccttatc
    34741 tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaagtc attgagttca
    34801 acgctcggtt cggagatcca gaaactcaga ttatcttgcc tcgcttgacc tctgactttg
    34861 ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcatgtgg acggacaagg
    34921 gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagactat gaaaggggcg
    34981 ttgagttgcc agcaaagaca gaaggcgatg tcatcaccta ctatgcaggg gctaagtttg
    35041 cggaaaatag cagagcactg ctctcaaacg gcggacgagt ttatatgctc gttaccacag
    35101 cagataccgt caaagaagcc caagccagca tctaccaaga actatcccaa caaaaaatag
    35161 aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga tataagaata
    35221 acgcgccgta gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca gaacagtgaa
    35281 tgttctggtc agggggaaac ttggagacct taggctcaaa gtttaggaat gaaaccgaag
    35341 gtttgcttcc gcctccatca cctaagacca ttatcaaaaa gaaaaataaa aattcacaaa
    35401 atacgttaat gatcgtatgg tttgcgagcg ttagcgagct aatatagaac aatcaccgcc
    35461 gttgtgaaag aacgattgga tgataatcca atcgttcagg gaaattggaa gaccttgggt
    35521 ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa gctaaggtga
    35581 ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc atcatgggct
    35641 caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc ttcggtgtag
    35701 cctacgaaaa gaaagttgtt tccgcacacc gtacaccaga cctcatgttc aaacatgcag
    35761 aagaagcccg tagtcgtggc atcaagatca tcatcgcagg tgctggtggc gcagcgcatt
    35821 tgccaggcat ggtagctgcc aaaacaaccc ttccagtcat tggtgtgcca gtcaagtctc
    35881 gtgctcttag tggagtggat tcactctatt ctatcgttca gatgccgggt ggggtgcctg
    35941 ttgcgaccat ggctatcggt gaagctggag cgactaacgc agctctcttt gccctccgtc
    36001 tcctctctgt agaagataag tccattgcgg atgcacttgc caactttgct gaagaacaag
    36061 gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat tatcggtggc
    36121 ggtcaactgg gtcagatgat ggccatttct gctatctaca tgggccacaa ggttatcgcg
    36181 ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt ggcaccttat
    36241 aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac ttacgagttt
    36301 gaaaatgtcg acgctgacgg tttggatgcc gttatcaagg atggacaact ccctcaagga
    36361 acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt gtcaaacaag
    36421 gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt ggcagatatc
    36481 gacttgtcga aaaactatgt cctcaagact gcgactggtg gctacgatgg tcatggacaa
    36541 aaggttattc gttcagaagc agacttggaa gcagcctatg cgctagcaga ctcagcagac
    36601 tgcgtcttgg aagaatttgt caactttgac cttgagattt ctgtcatcgt gtcaggaaat
    36661 ggcaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa tatcctgtct
    36721 aagaccatcg taccagcccg catttctgaa agtctagcag acaaggctaa agctatggca
    36781 gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat gtttgcgact
    36841 gatgatgacg ttattgtcaa tgaaatcgcc ccacgaccac ataactctgg gcactattct
    36901 attgaagcct gtgatttctc tcagtttgac acccatattc tcggtgttct cggagcacca
    36961 ttaccagtca tcaaactcca tgcgccagcc gttatgctta atgtcctcgg tcagcatgtc
    37021 gaggctgctg agcaatatgt gacagaaaat tcaagcgccc acctccacat gtatggtaaa
    37081 atagaagcga agcacaaccg caagatggga catgtgacct tgtttagtga tgtaccggat
    37141 agtgtggatg agcttgggga agggattgat ttttaggaca agtctatgat acaaattatc
    37201 gttaatacat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt gtatgccagt
    37261 gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata ccccgaaaat
    37321 tatttagcta tctatgatgt accgctggat acggatttga atacactaga tcattacccg
    37381 tctgtgttta ttgaaaaaga ggagtttgag tagaaatctt ggtttaccta gatagcttat
    37441 tcccaacagc ttaagaagaa aggaaaaatt aacacatgat caaccgttac tctcgccctg
    37501 agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag gtggaaatcc
    37561 tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg gctttgattc
    37621 gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag acgcgccacg
    37681 atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc aagtgggttc
    37741 actatgggtt aacttctacc gacgtggtgg atactgctta tggttacctc tacaagcagg
    37801 ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct gacaaggcca
    37861 aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct gagccgacaa
    37921 cctttggtct taaattggca acttggtaca gcgaaatgaa acgcaatatc gagcgtttcg
    37981 agcatgcagc tgctggtgta gaagctggta agatttctgg tgcggttggg aactttgcca
    38041 atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt gcccaagaaa
    38101 tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt cttgccagca
    38161 ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa tctgagcaac
    38221 gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg cctcacaaac
    38281 gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt ggtcacatga
    38341 ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac tcatcagctg
    38401 agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac cgttttggaa
    38461 atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg aactcgactt
    38521 ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc atgacccgtg
    38581 agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac caagtagact
    38641 ttaaaccact tcttgaggca gattcagaag taacatcacg tctcactcaa gaagaaatcg
    38701 atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt gaacgtcttg
    38761 gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt attttttatc
    38821 gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt ggacatgagt
    38881 cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt tttctctgtt
    38941 accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc agttgatgga
    39001 gctggttggc ttgggatttc tagttttggt ttttcttcag caatagcggc ttgtccgttt
    39061 tcatcgccta catgtgttac catagttccg acttcgacta tttgagtaac ggcttcctgt
    39121 gctacgacac tatttacaag tgttttcact tccttaccat cggcagaagt gctcacagag
    39181 tagaagttgc tacgatgtcc attgacgccc ttagtaatga cttgtgtttt tcctttgagt
    39241 aagagtggat tttcacgagt cactgtggta aatggaattt cttctttttg gatatccagt
    39301 ctaggtttta cctcagtagt tggtgcaaga ccactttcat cacccttgtg agttacagga
    39361 gcgccaactt caaccacttg gtttataact tctttggtta cctggctatc aaggactgtt
    39421 tctgttgttt ttccattttc agtgagtaca gagatgtaat gagttcgttc acctttgact
    39481 cctgctgtga taatattttc ctgaccagct gggaggttag gattttcttt cttgataact
    39541 tcaaatggaa tttcttcagt tcttgtgatg agttctggtc tggtttcaac attggcagcc
    39601 acttcatttt catctaggct tcctgaatga gttgcagctg gtttgaggcc ttgaagagcg
    39661 gcttttaggt tggctacaag tgtgtcaagc tcagcttgtt tattacggtt gaggttgtaa
    39721 tttagagctg ttttagctgc gtcaagggtc tcaagacttt ctttactata tccttctaag
    39781 tttgtaggaa ttttagctaa ttcttcgcgg agagcattat aattagcacg gaagtagtct
    39841 ttgttgtggt ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt gtattcagcg
    39901 cttggtctat ctgcccagat tgaaagcata cttccgactg ttggaagatc tacttcagga
    39961 tatttggtag aagctagttg attgaatggt gtttttccag tattctcaat agctttcttg
    40021 aggaaaccac caccatcttc tggtttttga ccaagaatgt agtaccagtc accgttggta
    40081 ttcaagaatt tatagccttt gcttgctagg tattgaggtg atgcgaggtt atatccccac
    40141 cagcctttag accagtaaga aatcaagaca tctttgtcaa actgaacatc gtccttgtct
    40201 tcatagtaga agccatcgtt gaaggccatt ggttgaagcc ctctttcttt ggccatagct
    40261 gcgagggtgt tggcatattc ggcaaatttg ccatagagtt gataccactt gaggtagtac
    40321 cagccttggg cactagtcgc atcgttggcg tattcgtcag taccaaagtt gaaaatcttt
    40381 gttttacctg caaagaagtc catgtattta ccgatgaggg cttttacaaa gttcatcgct
    40441 tcttcgtttt tcaagtccat agttgttttt gaaactttat caaagtgggc ttgaggattt
    40501 ttaataccta atttttccat ggcaaccagc atagcatcca tgtgacctgg actgttaata
    40561 gctgggatga gaccgatgtc cttagattta gcgtattcaa ttagctctgt tacttctgcc
    40621 tgtgttagtg cagtaccgtt tggatcgtcg tagtaagctt tagttccttc gataatagct
    40681 tttttaacgt catcactagc ataggttttt ccgttggcag taatggtcat atcatcgagt
    40741 agaaagcgaa gtccgtcatt tcctagaagg agatggacat cagaatatcc gagctcactg
    40801 gccttgtcta cgatgcgttt gagctggttc agagtaaagt atttgcgtcc agcatcgatt
    40861 gagattacct tgtttttggc aagtttttca acctcacgtt tagcttcttc ttctttttga
    40921 gcttcaggcg tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat ggcttgatca
    40981 atcgtatctt gttgggcacg gctaaggttg ctatcgagag agcgaatagc tttttcagct
    41041 tcttttacgg ccgtgacgct ttctgcagta taacggttca ggtcttttgg tacctcgtta
    41101 agtgcttgct ctgcagattc ataatcagct gcgaagtatt cagcgttggc atttgcaaaa
    41161 tgacgcatga gtttgaagag gcgtgatggt gaataacgtg cagatggagt gtcagcccaa
    41221 gcagctacca taccaccgat gattgggata tcagctcctt ctgtttttgg tacagaagtg
    41281 attggtgtgt ttttaatacc attgagcccc tgatcgagat tgtaccagcc ttggccatca
    41341 gcgtttcgtc caagaacgta gtaccaagca tcattggtat taaggatttg gtgacctttt
    41401 tcagctagta gtttagaaga agcgacatcg tagcctcccc aaccaccagt ccacatagaa
    41461 acgatgatgt ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta gataccgtcg
    41521 ttaaaggcca ttggtttgag accgtgcgat tttacaatac gagcgaggtc attggcgtag
    41581 gcaataaatt tttcatagcc ttttacaggg tagccttcgt ttggatagta tttatcagct
    41641 tgaagcacac tccaaccttt agcatctgtc gcatcattgg catattcatc aagtccgatg
    41701 ttgaagattt cagtcttttt cgcgaaataa gcagcatact tgtcgataag ggcttttgta
    41761 aaagcgacag cttgttcgtt gtcaagatcg acagtacggg ctgatttctt cccaaaatag
    41821 ctaaagttag ggttttggat tcccaattct ttcatggcat tgagaatcgc atccatgtgt
    41881 ccaggactat ttactgtcgg aatgagaccg atacctttat ctttggcata gttaatcaga
    41941 tctgtcattt gactttctgt taagtgattg ccgtttggat cgttgtaata atcatttgta
    42001 cctttttcaa tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt agctgtgatg
    42061 ctcatatcgt ccaacatgaa acggagtcca tcatttccga ctaataggtg taaatcagtg
    42121 tagccataat gtttcgcttt atcgatgatt tccttgagct gttctggtga gaaatattta
    42181 cgtccagcat caatagaaac aattttcttt ttcgctagtt tttcatttac agttgcagca
    42241 cgttcctttc ctgcctctgt ttccggtttg tcagcctctg ctttcgcttc atctttttta
    42301 gctggtttat ccttgtcagt cttgtctgta tttgactctt tagaatcaac ctctttcgct
    42361 tcttcctttt tagggctagc ttcttctgcc tttttattag cagtttcttt ttcagcagaa
    42421 gttggagtta ccacttctgc tttatcacta ggagttgaac taacttcctc ttgtggtttt
    42481 tcttctgttt ttggaagact agctacctta tcagtagctg gagtttctgt ttctacagtt
    42541 tttggagctt ctggttgaag ctctgcttta ggtgtttcct cagtccgatt ttcggatgat
    42601 tgaggggaat cagaaaccgt atggatggtc ggttggtttt ctgtagtagt aggagtaact
    42661 ccatcggctg caacagtctg tgcttggaag gcaaatccaa ttagaacaga agctgctcct
    42721 acagcgtatt tacgaataga aaaacgctgt tgtttttcat gtttcattgc aaaacctcct
    42781 gattgcattg ttatattgat agcgattata taaatcaacg cctttatttt atttcttata
    42841 ttaacgagag tcaagaggag atgacaaaaa actataataa gtataaaaaa atataaaatt
    42901 taaacttaag atttcagatt ggtcggaaaa aatgaatata tatatctagt ataatttttg
    42961 gttctatttc tataaaatat tccacaaatt atagaatctt ccaaaaatag gtaagcgcta
    43021 cctttttggt gtggtataat aagcatagaa aaagcccaag cgattagctc aggctttctt
    43081 cttagtgatc acggtcacat gagataaatt taatcttgta gtaatcagat cgtttgtaag
    43141 tttcactgta ttctaaaact tggccagttg attcgagttt ggtgatttta gtttgtagga
    43201 cagtagggaa ttgttcatcg actccgagga ctgaagccgc atgttctgga gttggaaaga
    43261 ctatttcgtt gatttcttca aagtgttcat cattcatgtg aatgtggtag tctaacttga
    43321 aacgattata gatagaacta tagtattcaa ggtttggata atttgcgttg atatattgtt
    43381 ctgggatgta ggatgtatgg tagatataaa cgacaccgtt tgattcgcgg atacgttcaa
    43441 tcttgtagta gaattgatcg ccgcgtagac ccaatttttc caagtaaaca agcttgtttc
    43501 cgcgttcaat tgaaagaaca gttaccttat catctttagc attgaagagt tcaatatctg
    43561 aaaactctac aagcttgtgt ttgcgcgcac gtgaaacgaa ggttcctttt ccttgttggc
    43621 ggacaatata gccatctttg gcaaggtcgt ttaaggcgcg aacaactgtg atagagctga
    43681 catcgtacat tgaaatgagt tctgcttcag tgtaaaattt atctccactg ctaaactgcc
    43741 cagagatgat tttatttttt aattcgtctt ttatgtattg atatttggga attgccatat
    43801 ttttacctct attttccttc tccatagaaa attttaccat aaaagcgaaa aaaatagtag
    43861 tcttttgaat aaaaaattag aataatagtt tgaaaaatta agcgatatag ggattgctca
    43921 tattttataa atgtattcta tacaaaatta ttttaggtcc tatattccga atttaaagag
    43981 cgtttgaaat gggtctaaaa atgtttgaaa ctaattgaat gtgtgtataa tagtaaaaat
    44041 gcagtaaata tcccgacaat ttctattgac aattcaaaca gattggttta taattaatat
    44101 aacaacaaat gaaagcgcaa actttcgcgg tcggaaggta gttttatgac acgatttgag
    44161 atacgagatg atttctatct cgatggaaaa tcatttaaga ttttatctgg tgccattcat
    44221 tattttaggg ttcctccaga ggattggtat cattcgctct ataacttgaa ggctcttggt
    44281 tttaatacgg tagagactta tgttgcttgg aatttacacg agcctcgtga aggtgagttt
    44341 cattttgacg gtgatctgga tttagagaaa tttctccaaa tagcgcagga tttgggtctc
    44401 tacgcaattg tgcgtccgtc tccatttatc tgtgcggaat gggaattcgg tggcttacca
    44461 gcttggctct tgaccaagaa catgcgaatt cgctcatccg acccagcata tatcgaggca
    44521 gttggtcgct actatgatca gttattgcca agactggttc ctcgtttgtt ggacaatggt
    44581 ggcaatattc tcatgatgca ggttgaaaat gagtatggtt cttacggaga agataaggct
    44641 tacctgagag cgattcgaca gctaatggaa gagtgtggcg taacctgtcc cctctttaca
    44701 tcagatggtc catggcgagc tactctgaaa gctggaacct taattgaaga ggacctcttt
    44761 gtaacaggaa actttggttc taaggcacct tacaactttt cgcagatgca ggaattcttt
    44821 gatgaacatg gtaagaaatg gccactcatg tgtatggagt tctgggatgg ttggtttaat
    44881 cgttggaaag aaccgattat cacacgggat cctaaggaat tggcagatgc agttcgagaa
    44941 gttttggaac aaggctccat caatctttac atgttccacg gtggtacaaa ctttggtttc
    45001 atgaatggtt gctcggctcg aggaactttg gacctgccac aagttacgtc ttatgattac
    45061 gatgcccttc tggatgaaga aggaaatcca actgctaaat atcttgcagt caagaagatg
    45121 atggcaacac atttttcaga gtatccgcag ttggaaccac tctacaaaga gagtatggag
    45181 ttggatgcta ttccactagt tgaaaaagtt tctttgtttg aaaccttaga tagcttgtca
    45241 agtcctgtag aaagtctcta tcctcaaaag atggaggagc tgggacaaag ttatggctac
    45301 ctactttatc gaacagaaac aaactgggat gcagaagaag aaagacttcg tatcattgat
    45361 ggtcgagata gggcccagct gtatgtcgat ggtcagtggg ttaaaactca atatcagaca
    45421 gagattgggg aagatatttt ttatcaaggt aaaaagaaag ggctatctag gttagatatc
    45481 ttgatagaaa atatggggcg tgtcaactat gggcataagt tcttagcgga tacgcaacgt
    45541 aagggaattc ggacaggggt ctgtaaggat ctgcatttct tactaaactg gaaacactat
    45601 ccactcccac tagacaatcc tgagaaaatt gatttttcaa aaggatggac tcaaggacaa
    45661 ccagcctttt acgcttatga ctttacagtc gaagagccaa aagatactta cctagacttg
    45721 tctgagtttg gtaagggggt tgcctttgtc aatgggcaga atctaggacg tttttggaac
    45781 gttggcccaa ctctctcact ttatatccct catagctatc tcaaggaagg tgccaaccgc
    45841 atcattatct ttgaaacaga aggtcaatat aaagaagaga ttcatttaac tcgtaaacct
    45901 acactaaaac atataaaggg ggaaaactta tgacaattgt aggatgccgt attgatggac
    45961 gtttgatcca cggacaagta gccaatcttt gggctggaaa actaaatgtt tcacgcatta
    46021 tggttgtaga cgacgaagtt gtcaacaacg atattgaaaa gagtggtttg aaacttgcga
    46081 caccaccagg tgtgaaattg agtattttgc cagttgagaa agctgcagcc aatattcttg
    46141 ctggcaaata cgatagccaa cgtctcttta tcgtggctcg taaaccagac cgcttccttg
    46201 gtttggtaga agcaggtgta ccacttgaaa cccttaatgt tgggaatatg tctcaaacac
    46261 cagaaactcg ttctattaca cgttctatca acgtagtaga caaggatgtg gaagacttcc
    46321 acaaactggc agaaaaaggt gttaaactta ctgctcagat ggttccaaat gatccaattt
    46381 cagacttttt gagcttatta aaataggaaa aaatttttta ggaggtcatt gttatgatac
    46441 aatggtggca aattttactt ctcactttgt actcagctta tcaaatctgt gatgagttga
    46501 cgatcgtttc atctgcaggt tcccctgtat ttgctggttt cattactggt ttaatcatgg
    46561 gagatgtgac tactggttta cttatcggtg gtaacttgca actgttcgtt cttggggttg
    46621 gtaccttcgg tggtgcttct cgtatcgacg caacttctgg tgcggttctt gcgacagcct
    46681 tctctgtttc acaaggaatt gatgcaccgc ttgcaattac tacaatcgct gtaccagtag
    46741 cagctctctt gacttacttc gacgttcttg gtcgtatgac tactaccttc ttcgctcacc
    46801 gtgtggatgc tgcaatcgaa cgctttgact ataaaggtat tgaacgcaac tacttgcttg
    46861 gtgcgattcc gtgggctcta tctcgtgccc ttccagtctt ctttgccctt gcttttggtg
    46921 gtgcctttgt acaatcagta gtagacttcg ttgaagccta caaatgggtt gcagatggct
    46981 tgacactcgc aggacgtatg cttccaggtc ttggatttgc aatcttgctt cgttaccttc
    47041 cagttaaacg taaccttcac taccttgcta tgggatttgg tttgacagct atgttgactg
    47101 ttctttactc atatgtaaca ggtcttggtg gcgctgttgc tggtatcgta ggtactcttc
    47161 ctgctgaagt tgctgacaaa attggtttcg tgaacaactt caaaggtttg tctatgattg
    47221 gtatttctat cgtaggtatt ttccttgcag tgcttcactt caaaaatagc caaaaagtag
    47281 ctgtagcagc accttctaca ccatcagaaa gtggggaaat cgaagatgac gaattctaat
    47341 tacaaactta caaaagaaga ttttaatcaa atcaacaaac gtagcttgtt tactttccaa
    47401 ttaggttgga actacgaacg tatgcaagct tctggttacc tttacatgat cttgcctcag
    47461 ttgcgtaaaa tgtatggtga tggaactcct gaattgaaag aaatgatgaa agttcatact
    47521 caattcttca atacttcacc attcttccat accattatcg ctggttttga ccttgccatg
    47581 gaagaaaaag atggtgtagg ttcaaaagac gctgttaacg gtatcaagac aggtttgatg
    47641 ggaccattcg ctcctcttgg ggatacaatc tttggttcac ttgtacctgc tatcatgggg
    47701 tcagtcgcag caactatggc tatcgctggc caaccttggg ggatcttcct ttggattgca
    47761 gttgcagtag cgtatgacat cttccgttgg aaacagttgg aatttgctta caaagaaggg
    47821 gttaacctta tcaacaacat gcaaagtacc ttgacagctt tgattgacgc tgcatctgta
    47881 cttggtgtct tcatgatggg tgctcttgta gcaacagtga ttaactttga aatttcttac
    47941 aagttgccaa tcggtgaaaa gatgattgat ttccaagaca tcttgaacca aatcttccca
    48001 cgtttgcttc cagcaatctt tactgccttt atcttctggt tgcttggtaa aaaaggtatg
    48061 aactctacta aagctatcgg tattattatc gtacttgctt tggctctttc tgcccttggt
    48121 cactttgcac ttggaatgta attccttatg actaaatcat taattttggt gagccatggt
    48181 cgcttctgtg aggagcttag aggtagcaca gaaatgatta tgggcccaca agacaacatt
    48241 tacacagtag ctcttcttcc agaagatggc ccagaagaat ttactgctaa atttgaagct
    48301 gttattgaag gattggatga tttcctagtc tttgcggatc ttctcggtgg gacaccttgt
    48361 aatgtggtga gtcgcttgat catggaaggt cgtgatattg acctttacgc agggatgaat
    48421 cttccaatgg tgattgaatt tatcaatgcg agccttacag gcgcagatgc ggactacaag
    48481 agccgtgctg cagaaagcat tgtgaaagtt aatgacctgt tagcgggctt cgatgatgac
    48541 gaagatgaat aatactcttc gaaaatctct tcaaactacg tcaacgtcgc cttgccgtag
    48601 gtatatgtta ctgacttcgt cagtcttatc cggcaacctc aaagcggtgc tttgagcagc
    48661 ctgcggctag tttcctacag attttagttg gaactcgatt caattcatgt gacaacgtga
    48721 aaatcgttag agcattttat atagaatata catgggaatg gagcttactc ccattcccat
    48781 atttaataga aaaagaggaa ctcaatgcta cattatacaa aagaagactt gctcgaattg
    48841 ggtgcagaaa tcactacgcg tgaaatctac caacagcctg atgtatggag agaagctttt
    48901 gaattttatc aagcaaaacg tgaagaaatt gcagcctttc tacaagaaat cgctgataaa
    48961 catgactata ttaaggttat cttgacaggt gctgggactt ctgcttatgt gggagatacc
    49021 ttgctacctt actttaagga agtctatgac gaacgcaaat ggaatttcaa tgctattgcg
    49081 acaacagata tcgttgccaa accagcaacc tatttgaaaa aagatgtggc aactgtcctt
    49141 gtgtcttttg ctcgtagtgg gaactcgcct gaaagtgtgg cgactgttga tttggccaaa
    49201 tccttggtgg atgagcttta tcaagtgacg attacttgtg caacagatgg taaattggct
    49261 cttcaagctc acggtgatga ccgtaatctc ttgctcttgc aaccagctgt ctctaatgat
    49321 gctggatttg ccatgacttc tagctttacg tctatgatgt tgacagctct cttggtcttt
    49381 gatcctacag aatttgctgt taagtctgaa cgttttgaag ttgtatctag tcttgcccgt
    49441 aaagttttag acaaggtaga agatgtcaaa gagctcgttg atttagactt taaccgtgtc
    49501 atctatctag gcgctggtcc tttctttgga cttgctcatg aagctcagct caagattttg
    49561 gaattaactg ctggtcaagt tgcgaccatg tatgaaagcc cagttggctt ccgtcacggt
    49621 ccaaaatctc ttatcaacga caatacagtt gttttggtct ttggtacaac gacagcctac
    49681 actcgtaagt acgacttgga cttggttcgt gaagttgctg gtgaccagat tgctcgtcgt
    49741 gttgtgcttt tgagtgatca agcttttggt cttgaaaatg tcaaagaagt ggtccttggt
    49801 tgtggcggtg tcttgaatga tatttaccgt gtcttccctt acatcgttta tgcccaactc
    49861 tttgctctat tgacttcact caaggtagaa aataaaccag atacaccgtc tcctacaggt
    49921 acagtaaacc gtgtagtaca aggtgtcata attcacgaat atcaaaagta agacagtgtt
    49981 tatgaattct tgacaagagg atttgtaaat tatcagataa accatagatt gtcagtacgc
    50041 tttctatggt ttgtttgctt gagagaaata gtaaaaggag aacagaatga aagcatacac
    50101 agagcgtgta tttggaaatg ttgagggcga ggatgtcttg gcctatcgat ttgagacaga
    50161 cggtggctac caacttgagg ttatgactta tggcgcgacc atcttgcgct atgtcgcacc
    50221 tgacaaggct ggaaattttg ccaatgttat cttgggattt gatgactttg atagttatgt
    50281 aggcaatagt cccaagcatg gagcaagtgt aggtcctgta gcgggtcgta ttgcaggtgc
    50341 gacctttgag ctcaatggta agacctatga ccttgaggtt aataatgcta gcaactgtaa
    50401 tcacagtggt tcaactggtt gggattccag cttgtttgaa gttgaagaag taagcgatca
    50461 tggcttgact ctctacacag agcgtacaga tgggacagga gggttccctg gaaatctcaa
    50521 gatttggatc agttatcact tggaagaaac tggtgcctat gaaatcatct acaaggtaac
    50581 gaccgatcag gatacgctgg tcaatccaac caaccacagc tatttcaact tgtctggtga
    50641 tttcacgcag acgattgacc gtcatgtctt ccaactaaac acagagggca tttactcaat
    50701 cgctcctgac ggtgttcctg ccaaaactcc agaagccaac cgtgatgtgg tcaaacacat
    50761 ctacaatggt accttgttga aggatatctt tgcagaagaa gatgagcaaa tccagctggc
    50821 atcaggtttg gatcacccat ttgcccttcc tgcaggccat gacaatgctg gattccttta
    50881 tgaccaaaat tcaggtcgct tcctgctttt caagacagaa gctccttgct ttgtggtcta
    50941 cacagcaaac tttgtggatg aaagtgtcat cataggaggt cagccaatgc tacagcacaa
    51001 tgggattgct cttgaagcgc aagctttacc agatgccatt cacagtgacc ttaaaggcca
    51061 agtcattctt aaagctggtc aaaccttcac cagtaagaca cgttatgaac ttgttgtgaa
    51121 ataaaaaaag ctggtcaaaa agtctttaaa attaaaataa cgcatattgt caggtgatga
    51181 aaagtttgat aatatgcgtt ttattatgaa atgatttact ttatcttatc ctgaaatggt
    51241 gttatttttg agttatctgg cttgactttc ttgatggaaa ttatataata gttgtaataa
    51301 caataattac aacgagaaaa gaggaccatt tatgacctat gaatacaaga gtcacattta
    51361 tttggcagag acagttttaa atgtaaagga tttggccagt caaacagcct tttatcagca
    51421 agttattggt ttagaaatct tatctcaaac tgagacagag tccattctag gccttggtgg
    51481 aaaagtcttg gtacagctga ttcaagcaca agagagcgga gaagtgaggg aacattatgg
    51541 tctttaccat ttggccattc tcttgcccac acgcaaggct ttggctgatg tcttgaaaca
    51601 cctgacagat ttgcaaattc ctcttgtcgg cggtgcagac catggttaca gtgaagctat
    51661 ttacttggaa gatttggagg gaaatggcat tgaactctat cgagataagc cagtttccac
    51721 atggaatatt cgagaagatg gacgcattat cggagtgacg gaggctcttg cggcgcagga
    51781 catttatgag ttgggggaaa gagtagagcc ctttatcctg gcagaaggta caagaatggg
    51841 gcatattcat ctttccgtca aggatagtcg aaagtccagc cagttttatc aaaaggtgtt
    51901 agggctagag aataaattca gtgtgcctgg cgctagttgg attgcggctg gagattacca
    51961 tcatcattta gcagttaacg aatggggagg aaaaggtctg gcttcgcgta agcaaggctt
    52021 accaggttta gcctactatg tcatcgaagt cgcacataaa aaagaactgt taacgattgc
    52081 ccaacgagca caagaagttg acgcaccaat caaatggatg acatcgagcc aattggaaat
    52141 cacagactca gatggcatcg tgacccgtat tcgtttagca aggtaaaatt aggaattttt
    52201 aataagttat aagtattgct agtttgcttt ttgaacggtc tttggtaaca gaactgcgtg
    52261 agctggatgg gtgagaattt tgacaaagaa gctgattaga gatataatga agaaaaatcg
    52321 agcaaggaaa aagaaatgac aaattcaaag tatattactt gtttgaaacg ttcagagggc
    52381 cagttgtgtg gaattcaaaa gatgattgaa ggagatcgtg actgtgctga tattgtgacg
    52441 caactgacag cagtgaaatc tagtgtagag cgcgtgattg agatgataat taccgaaaat
    52501 cttactgaat gtatcaatca gccactagat gattctgaag ctcaaaagga acgcctagaa
    52561 aaggctatcc gatacttgat taaacggaaa taaatgaatg ttttgagacg atatgtgcaa
    52621 aggtctatta actattagaa tagtttaatg tgagtcaaaa gaagttgtaa aaaatcttta
    52681 aaattaaaaa acgcatagta tcaggtattg aaatgtactg ccccccaaaa gttagattct
    52741 ttctgtctaa cttttggggg gcagtacata aaaaccttga tagtatgcgt tttattgtgg
    52801 ggagacttat actcttcgaa aatctcttca aaccacgtca gtttcacctt gccgtagata
    52861 tggttactga cttcgtcagt tc
//
LOCUS       DAYYYC010000010        48135 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.010, whole genome shotgun sequence.
ACCESSION   DAYYYC010000010 DAYYYC010000000
VERSION     DAYYYC010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48135
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.010"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            26..106
                     /locus_tag="ACHBV5_000560"
     tRNA            26..106
                     /locus_tag="ACHBV5_000560"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60..62,aa:Tyr,seq:gta)
     gene            111..181
                     /locus_tag="ACHBV5_000561"
     tRNA            111..181
                     /locus_tag="ACHBV5_000561"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:143..145,aa:Trp,seq:cca)
     gene            196..268
                     /locus_tag="ACHBV5_000562"
     tRNA            196..268
                     /locus_tag="ACHBV5_000562"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:229..231,aa:His,seq:gtg)
     gene            279..350
                     /locus_tag="ACHBV5_000563"
     tRNA            279..350
                     /locus_tag="ACHBV5_000563"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:311..313,aa:Gln,seq:ttg)
     gene            360..443
                     /locus_tag="ACHBV5_000564"
     tRNA            360..443
                     /locus_tag="ACHBV5_000564"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:394..396,aa:Leu,seq:caa)
     gene            550..1827
                     /locus_tag="ACHBV5_000565"
     CDS             550..1827
                     /locus_tag="ACHBV5_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HFM9966413.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1903..3387
                     /gene="thrC"
                     /locus_tag="ACHBV5_000566"
     CDS             1903..3387
                     /gene="thrC"
                     /locus_tag="ACHBV5_000566"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HFM9966414.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIALLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILELFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQAAVEAYLGL"
     gene            3448..4728
                     /locus_tag="ACHBV5_000567"
     CDS             3448..4728
                     /locus_tag="ACHBV5_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFM9966415.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4732..5352
                     /locus_tag="ACHBV5_000568"
     CDS             4732..5352
                     /locus_tag="ACHBV5_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFM9966416.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5518..6660
                     /locus_tag="ACHBV5_000569"
     CDS             5518..6660
                     /locus_tag="ACHBV5_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFM9966417.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQETTPGEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            6980..7404
                     /locus_tag="ACHBV5_000570"
                     /pseudo
     CDS             6980..7404
                     /locus_tag="ACHBV5_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            7415..7773
                     /locus_tag="ACHBV5_000571"
                     /pseudo
     CDS             7415..7773
                     /locus_tag="ACHBV5_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            7880..8497
                     /gene="pcp"
                     /locus_tag="ACHBV5_000572"
                     /pseudo
     CDS             7880..8497
                     /gene="pcp"
                     /locus_tag="ACHBV5_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(8525..9382)
                     /locus_tag="ACHBV5_000573"
     CDS             complement(8525..9382)
                     /locus_tag="ACHBV5_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFM9966418.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVFFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9512..10654
                     /gene="tgt"
                     /locus_tag="ACHBV5_000574"
     CDS             9512..10654
                     /gene="tgt"
                     /locus_tag="ACHBV5_000574"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFM9966419.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            10752..12569
                     /locus_tag="ACHBV5_000575"
     CDS             10752..12569
                     /locus_tag="ACHBV5_000575"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFM9966420.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTV
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12722..13873
                     /gene="nagA"
                     /locus_tag="ACHBV5_000576"
     CDS             12722..13873
                     /gene="nagA"
                     /locus_tag="ACHBV5_000576"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFM9966421.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14036..15094
                     /locus_tag="ACHBV5_000577"
     CDS             14036..15094
                     /locus_tag="ACHBV5_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HFM9966422.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15245..15610
                     /locus_tag="ACHBV5_000578"
     CDS             15245..15610
                     /locus_tag="ACHBV5_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFM9966423.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            15686..16627
                     /gene="comGA"
                     /locus_tag="ACHBV5_000579"
     CDS             15686..16627
                     /gene="comGA"
                     /locus_tag="ACHBV5_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFM9966424.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16575..17591
                     /gene="comGB"
                     /locus_tag="ACHBV5_000580"
     CDS             16575..17591
                     /gene="comGB"
                     /locus_tag="ACHBV5_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFM9966425.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            17593..17919
                     /gene="comGC"
                     /locus_tag="ACHBV5_000581"
     CDS             17593..17919
                     /gene="comGC"
                     /locus_tag="ACHBV5_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HFM9966426.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNGGA
                     NRKVND"
     gene            17912..18316
                     /gene="comGD"
                     /locus_tag="ACHBV5_000582"
     CDS             17912..18316
                     /gene="comGD"
                     /locus_tag="ACHBV5_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFM9966427.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQMISNGSQKLPVPKGIQAPSGQSIIFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18279..18581
                     /gene="comGE"
                     /locus_tag="ACHBV5_000583"
     CDS             18279..18581
                     /gene="comGE"
                     /locus_tag="ACHBV5_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HFM9966428.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQININGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            18544..19005
                     /gene="comGF"
                     /locus_tag="ACHBV5_000584"
     CDS             18544..19005
                     /gene="comGF"
                     /locus_tag="ACHBV5_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFM9966429.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVRFRFQFQKGLEREFIYRVEKEKS"
     gene            18983..19396
                     /gene="comGG"
                     /locus_tag="ACHBV5_000585"
     CDS             18983..19396
                     /gene="comGG"
                     /locus_tag="ACHBV5_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFM9966430.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            19533..20120
                     /locus_tag="ACHBV5_000586"
     CDS             19533..20120
                     /locus_tag="ACHBV5_000586"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM9966431.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKEILDFG
                     GGTGLLALPLAKQAKSVTLVDISEKMLEQAHLKAEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVHSQILYSAEDLFQGNHSEFFLIVAQKSLA"
     gene            20181..21134
                     /locus_tag="ACHBV5_000587"
     CDS             20181..21134
                     /locus_tag="ACHBV5_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM9966432.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVELFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21185..22375
                     /locus_tag="ACHBV5_000588"
     CDS             21185..22375
                     /locus_tag="ACHBV5_000588"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0016774 - phosphotransferase activity,
                     carboxyl group as acceptor [Evidence IEA];
                     GO_process: GO:0006082 - organic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFM9966433.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGTDAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22376..22507
                     /locus_tag="ACHBV5_000589"
     CDS             22376..22507
                     /locus_tag="ACHBV5_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966434.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            22524..22895
                     /gene="rnpA"
                     /locus_tag="ACHBV5_000590"
     CDS             22524..22895
                     /gene="rnpA"
                     /locus_tag="ACHBV5_000590"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFM9966435.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            22870..23694
                     /locus_tag="ACHBV5_000591"
     CDS             22870..23694
                     /locus_tag="ACHBV5_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFM9966436.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            23713..24699
                     /gene="jag"
                     /locus_tag="ACHBV5_000592"
     CDS             23713..24699
                     /gene="jag"
                     /locus_tag="ACHBV5_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFM9966437.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            24750..25373
                     /locus_tag="ACHBV5_000593"
     CDS             24750..25373
                     /locus_tag="ACHBV5_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HFM9966438.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLEKQAKILDIPTVKGIYYLAYSDGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            25504..26961
                     /locus_tag="ACHBV5_000594"
     CDS             25504..26961
                     /locus_tag="ACHBV5_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFM9966439.1"
                     /translation="MEVISSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            26984..27265
                     /locus_tag="ACHBV5_000595"
     CDS             26984..27265
                     /locus_tag="ACHBV5_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM9966440.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27342..27827
                     /locus_tag="ACHBV5_000596"
     CDS             27342..27827
                     /locus_tag="ACHBV5_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFM9966441.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            27844..28509
                     /locus_tag="ACHBV5_000597"
     CDS             27844..28509
                     /locus_tag="ACHBV5_000597"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFM9966442.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            28513..29376
                     /locus_tag="ACHBV5_000598"
     CDS             28513..29376
                     /locus_tag="ACHBV5_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFM9966443.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29378..30082
                     /locus_tag="ACHBV5_000599"
     CDS             29378..30082
                     /locus_tag="ACHBV5_000599"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFM9966444.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIIVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30261..31934
                     /locus_tag="ACHBV5_000600"
     CDS             30261..31934
                     /locus_tag="ACHBV5_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFM9966445.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32046..33137
                     /gene="ulaG"
                     /locus_tag="ACHBV5_000601"
     CDS             32046..33137
                     /gene="ulaG"
                     /locus_tag="ACHBV5_000601"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFM9966446.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33251..35227
                     /gene="tkt"
                     /locus_tag="ACHBV5_000602"
     CDS             33251..35227
                     /gene="tkt"
                     /locus_tag="ACHBV5_000602"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFM9966447.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35344..35643
                     /gene="yajC"
                     /locus_tag="ACHBV5_000603"
     CDS             35344..35643
                     /gene="yajC"
                     /locus_tag="ACHBV5_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFM9966448.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            35690..36118
                     /locus_tag="ACHBV5_000604"
     CDS             35690..36118
                     /locus_tag="ACHBV5_000604"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFM9966449.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEILYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36120..36530
                     /locus_tag="ACHBV5_000605"
     CDS             36120..36530
                     /locus_tag="ACHBV5_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HFM9966450.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            36831..39482
                     /gene="adhE"
                     /locus_tag="ACHBV5_000606"
                     /gene_synonym="adhC"
     CDS             36831..39482
                     /gene="adhE"
                     /locus_tag="ACHBV5_000606"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFM9966451.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(40390..40698)
                     /locus_tag="ACHBV5_000607"
     CDS             complement(40390..40698)
                     /locus_tag="ACHBV5_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFM9966452.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEVHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(40695..41003)
                     /locus_tag="ACHBV5_000608"
     CDS             complement(40695..41003)
                     /locus_tag="ACHBV5_000608"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM9966453.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(41008..42303)
                     /locus_tag="ACHBV5_000609"
     CDS             complement(41008..42303)
                     /locus_tag="ACHBV5_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFM9966454.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(42321..43730)
                     /locus_tag="ACHBV5_000610"
     CDS             complement(42321..43730)
                     /locus_tag="ACHBV5_000610"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFM9966455.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            43888..44616
                     /locus_tag="ACHBV5_000611"
     CDS             43888..44616
                     /locus_tag="ACHBV5_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFM9966456.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            45075..45269
                     /locus_tag="ACHBV5_000612"
     CDS             45075..45269
                     /locus_tag="ACHBV5_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFM9966457.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(45391..45557)
                     /locus_tag="ACHBV5_000613"
                     /pseudo
     CDS             complement(45391..45557)
                     /locus_tag="ACHBV5_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(45635..46945)
                     /locus_tag="ACHBV5_000614"
     CDS             complement(45635..46945)
                     /locus_tag="ACHBV5_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HFM9966458.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALKLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            47182..48054
                     /gene="nadC"
                     /locus_tag="ACHBV5_000615"
     CDS             47182..48054
                     /gene="nadC"
                     /locus_tag="ACHBV5_000615"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HFM9966459.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT        14713 a         8551 c        10520 g        14351 t
ORIGIN      
        1 ccgtctcgcg ccatttatat attttggaag ggtagcgaag aggctaaacg cggcggactg
       61 taaatccgct ccttcgggtt cgggggttcg aatccctccc cttccatttt acgggcatag
      121 tttaaaggta gaactaaggt ctccaaaacc ttcagtgtgg gttcaattcc tactgcccgt
      181 gttaatagaa ttatggcggg tgtggtgaag tggttaacac accagattgt ggctctggca
      241 tgcgtgggtt cgatccccat cactcgccta ttttatattg gggtatagcc aagcggtaag
      301 gcaagggact ttgactccct catgcgttgg ttcgaatcca gctaccccag ttactatttg
      361 ccggcgtggc ggaattggca gacgcgctgg actcaaaatc cagtgtccgc aaggacgtgc
      421 cggttcgacc ccggccgccg gtatagtata gtgttaggaa cgttgttatt cttcgttcct
      481 tttttatatt atttttggta taattatagt tattcaaatt ttgtttagat tgagaaagtg
      541 tagggtagta tgtcttgttc tatcgattta ttaaaacatc ggtatttgaa aaatattaaa
      601 gaaaatcctg aattgtttgt cggaattgag ttggagtatc ctgttgcaag tttagaaggg
      661 gatgctacag atgttgaagt tataaaggat ctatttcatt atttagtttc tactttggat
      721 ctcaccgtag caaaggtaga tgattttggc aatctgatcc agttagtaga tccgataagt
      781 caggatgcta ttttatttga agtttcctat acaacgattg agtttgcatt tggtaaggct
      841 gaaacgattc aagaggtcga aaatcgtttc aataattata tgaatgtaat tcagagaaag
      901 ttagctgaat caaatcatgc tattgttggc tgtggtatcc atcccaactg ggataaaaat
      961 gagaattgtc cagtggctta tccacgctat cagatgttga tggattattt gaatttgagt
     1021 agaaatatta ttaaatcaga tttacatcat ttccctgaat atggtacttt tatctgtggg
     1081 agccaggttc agctggatat ttcaaaaacc aactacttac gggtgattaa tgcttttact
     1141 caaattgaag cggctaaggc ttatttattt gcaaactctg aattttcggg tgcggattgg
     1201 gatacgaaaa tttcaaggga tattttctgg gaagaatcta tgcatggtat ctatccagag
     1261 aatgttgggg tcaatgctag actccttaat gatgaagctg atttttttga ctatctaaat
     1321 cattctgcga tttttactgc ggaacgtgat gggcagacct attattttta tcctattcag
     1381 gctggggact atttggctac gcctgaaatc caagcatttg ctctgaatgg ggatgaggtt
     1441 attatttccc cccaagagaa ggattttgaa actcatcgta gttaccagta ccaagactta
     1501 acgactcgag gaacagttga gtttcgtagt gtgtgtacac agccacttga taggactttt
     1561 gcttctgcag cttttcactt gggattattg gttaatttag acaagttaga agcttactta
     1621 gaaacagcac ctttctttaa agtatttggt tatgattaca agtctttaag gagacaattt
     1681 tctaagaaaa atcttacaga tgaggaagaa actacgatta ttgaattttc caaagactta
     1741 ctcctactag ctgaggaggg actagtggtg agaaataagg aagaaatgac ctatttacag
     1801 cctttgagag aagaattgag cctataattt ctcttataaa gggagaattt tctgaaaaat
     1861 catgatataa tggacgagac tatagataaa ggatagagag taatgacatt agtttatcaa
     1921 tcaacgcgtg atgccaacaa tacagtaact gccagccaag caattttgca aggtttggcg
     1981 acggacggcg gtttgtttac accggttact tatccaaagg tagatttgga ctttgacaaa
     2041 ttgaaagatg cttcttacca ggaagttgct aagctagttt tgtcagcatt tttagatgac
     2101 tttacagctg aggagttgga ctactgtatc aacaatgcct acgatagcaa atttgatact
     2161 ccagctattg cactattagt gaaattagat gggcaataca atttggaact tttccatggt
     2221 tcaacgattg cctttaagga tatggccttg tctattttgc catactttat gacgactgct
     2281 gctaagaaac atggtttgga gaacaagatt gttatattga cagcgacatc tggtgacacg
     2341 gggaaagctg ctatggcggg gtttgcggat gtgcctggta ctgagattat cgtcttttat
     2401 ccaaaggatg gtgtcagcaa gattcaagag ttacaaatga ccactcagac tggcgacaat
     2461 actcatgtta ttgctattga tggtaacttt gacgatgcgc aaacaaatgt gaagcacatg
     2521 tttaacgatg tggctcttcg tgaaaaattg actaccaaca agttgcaatt ttcatcagct
     2581 aactctatga acattggtcg tctggtgcca caaattgttt attatgttta tgcttacgct
     2641 caattggtta agactggtga aattgtagct ggtgaaaagg ttaacttcac agtaccaaca
     2701 ggaaactttg gaaatatctt ggctgccttt tatgccaaac aaattggttt gccagttggt
     2761 aaattgatct gtgcttcaaa tgacaacaat gttttgacag acttctttaa aacacgtgtc
     2821 tatgacaaaa aacgtgagtt taaggtaaca accagcccat ctatggatat cttggtatct
     2881 tcaaacttgg agcgcttgat tttccatctt ttgggaaata atgctgaaaa gacagctgaa
     2941 ctcatgaatg ctttgaacat gcaaggacaa tataagttga cagactttga tgcagagatt
     3001 ctggagctct ttgcagctga atatgcgact gaggaagaaa cagcggcaga aatcaagcgt
     3061 gtttatgagt tagattctta tattgaggat ccacatacgg cggttgcctc agcagtttat
     3121 agaaaatacc aagcggttac tgatgatgcg actaagacag tgattgcttc aacagctagt
     3181 ccctacaagt tcccagtagt tgcagtagaa gctgtaactg gaaaagcagg tttaacagac
     3241 tttgaagcct tggctcaatt acatgaaatc tcaggcgttg cagtgccacc agcagttgat
     3301 gggcttgaga cagctcctgt tcgtcacaag acaactgtag cggctgctga tatgcaagca
     3361 gcggttgagg cttatttagg actttaagat agagggagta aactcggttg ggaaaccaac
     3421 tgagtttctt ttcatcagga ggagagattg tttaagaaaa ataaagacat tcttaatatt
     3481 gcattgccag ctatgggtga aaactttttg cagatgctaa tgggaatggt ggacagttat
     3541 ttggttgctc atttaggatt gatagctatt tcaggggttt cagtagctgg taatattatc
     3601 accatttatc aggcgatttt catcgctctg ggagctgcta tttccagtgt tatttcaaaa
     3661 agcatagggc agaaagacca gtcgaagttg gcctatcatg tgactgaggc gttgaagatt
     3721 accttactat taagtttcct tttaggattt ttgtccatct tcgctgggaa agagatgata
     3781 ggacttttgg ggacggagag ggatgtagct gagagtggtg gactgtatct atctttggta
     3841 ggcggatcga ttgttctctt aggtttaatg actagtctgg gagccttgat tcgtgcaacg
     3901 cataatccac gtctgcctct ctatgttagt tttttatcca atgccttgaa tattcttttt
     3961 tcaagtctag ctatttttgt tctggatatg gggatagctg gtgttgcttg ggggacaatt
     4021 ctgtctcgtt tggttggtct tgtgattttg tggtcacaat taaaactgcc ttatgggaag
     4081 ccaacttttg gtttagataa ggaactgttg accttggctt taccagcagc tggagagcga
     4141 cttatgatga gggctggaga tgtagtgatc attgccttgg tcgtttcttt tgggacggag
     4201 gcagttgctg ggaatgcaat cggagaagtc ttgacccagt ttaactatat gcctgccttt
     4261 ggcgtcgcta cggcaacggt catgctgttg gcccgagcag ttggagagga tgattggaaa
     4321 agagttgcta gtttgagtaa acaaaccttt tggctttctc tgttcctcat gttgcccctg
     4381 tcctttagta tatatgtctt gggtgtacca ttaactcatc tctatacgac tgattctcta
     4441 gcggtggagg ctagtgttct agtgacactg ttttcactac ttgggacccc tatgacgaca
     4501 ggaacagtca tctatacggc agtctggcag ggattaggaa atgcacgcct ccctttttat
     4561 gcgacaagta taggcatgtg gtgtatccgc attgggacag gatatctgat ggggattgtg
     4621 cttggttggg gcttgcctgg tatttgggca gggtctctct tggataatgg ttttcgctgg
     4681 ttatttctac gctatcgtta ccagcgctat atgagcttga aaggatagga aatgcaaaaa
     4741 acagctttta tttgggattt agacgggact ttattggact cttacgaagc gattttatca
     4801 gggattgagg agacttttgc tcagttttct attccttatg ataaggagaa ggtgagagag
     4861 tttatcttca agtattcggt gcaaaatttg cttgtgcggg tggcagaaga tagaaatctg
     4921 gatgttgagg tgctaaatca ggtgcgtgcc cagagtctgg ctgagaaaaa tgctcaggta
     4981 gttttgatgc caggtgcgcg tgaggtgcta gcttgggcag acgaatcagg aattcagcag
     5041 tttatatata ctcataaggg gaacaacgct tttaccattc tcaaggactt gggggtggaa
     5101 tcctatttta cagagatttt aaccagtcag agtggctttg tgcggaagcc aagtccagaa
     5161 gcggctacct atctgctaga taagtatcag ttgaattctg ataatactta ttatataggg
     5221 gatcggactc tggatgtgga atttgcccag aatagtggga ttcaaagtat caacttttta
     5281 gagtctactt atgaagggaa tcacaggatt caagcgttag cagatatttc ccgtattttt
     5341 gagactaagt gataaaaaga ttgtgtcagt tttgtgacag agacctaaca aactatttca
     5401 agtaacctag tttgttacaa ggaatagaca gttctgttaa ataggcccga gagggctttt
     5461 tttctacatt ttttgtgtta tgatagacag gtactaattt gaaaggaatt tgaaagaatg
     5521 aagaaaagaa tgttattagc gtcaacagta gccttgtcat ttgccccagt attggcaact
     5581 caagcagaag aagttctttg gactgcacgt agtgttgagc aaatccaaaa cgatttgact
     5641 aaaacggaca acaaaacaag ttataccgta cagtatggtg ataccttgag cactattgca
     5701 gaagccttgg gtgtagatgt cacagtgctt gcgaatctga acaaaatcac taatatggac
     5761 ttgattttcc cagaaactgt tttgacaacg actgtcaatg aagcagaaga agtaacagaa
     5821 gttgaaatcc aaacacctca agcagactct agtgaagaag tgacaactgc gacagcagat
     5881 ttgaccacta atcaagtgac cgttgatgat caaactgttc aggttgcaga cctttctcaa
     5941 ccaattgcag aagctccaaa agaagtagca tcaagttcag aagttacaaa gacagtgatt
     6001 gcttctgaag aagtggcacc atctacgggc acttctgtcc cagaggagca aacggccgaa
     6061 acaagcagtg cagttgcaga agaagctcct caggaaacga ctccaggtga gaagcaggaa
     6121 acacaagcaa gccctcaagc agcatcagca gtggaagcaa ctacaacaag ttcagaagca
     6181 aaagaagtag catcatcaaa tggagctaca gcagcagttt ctacttatca accagaagag
     6241 acgaaaataa tttcaacaac ttacgaggct ccagctgcgc ccgattatgc tggacttgca
     6301 gtagcaaaat ctgaaaatgc aggtcttcaa ccacaaacag ctgcctttaa agaagaaatt
     6361 gctaacttgt ttggcattac atcctttagt ggttatcgtc caggagacag tggagatcac
     6421 ggaaaaggtt tggctatcga ttttatggta ccagaaagtt cagaattagg ggataagatt
     6481 gcggaatatg ctattcaaaa catggccagc cgtggcatta gttacatcat ctggaaacaa
     6541 cgtttctatg ctccattcga tagcaaatat gggccagcta acacttggaa tccaatgcca
     6601 gaccgtggta gtgtgacaga aaatcactat gaccacgttc acgtttcaat gaatggataa
     6661 acccgacttg gtaacatcat tttgacgaat gagatctagc tttcgtgata ggaagcgatt
     6721 ctcgttcgtt ttttctttgt catactcttc gaaaatctct tcaaaccacg tcagttttat
     6781 ctgaaacctc aaagctgtgc tttgagcaac ctgcgactag ctttctagtt tactctttga
     6841 ttttcattga gtatcaattt gaatggaaaa tggaaagtta ttatcttgta ataatccaag
     6901 caacattctt gcaatctatt ttactttata tcacaattga ttggtcaact attgataagt
     6961 caatggatag gaggaagaaa tgatagagat tcaagattta ctgtatcaac tccgcttgtc
     7021 tgagcaagcg agtacgcaat tgtttgaaaa aggcttggga ttagtttgac acggtatcag
     7081 attttactgt ttttgctgga gcattctcct tgtaaccaaa tggcggttca ggagcgtttg
     7141 aaaattgatc aggctgcttt gacacggcat ttcaagattt tggaaacgga aggtttggtg
     7201 gagcgtcatc gtaatcctga aaatcagcgg gaagtgttgg tagaggctgc gaagtatgcc
     7261 aaggagcagt tagtggtgaa tccccctctg caacatatca aggttaagga agagatggaa
     7321 agtatcttaa cagagtttga gagaacagaa ctcagccgtt tattaaataa attggttttg
     7381 ggtattgaaa atatagaaat ttaaggagaa atagatgtca attattttaa caacgatcgt
     7441 tgctttggag catttttaca ttttttattt ggaaagtatt gccacgcaat cagatgcgac
     7501 tagtcgtgta tttaatatgg aaaaggaaga attggctcat ccgtcagtaa gttcattgtt
     7561 caaaaatcaa ggaatttata aggctctgct aggagtcttt ctcttgtatg tcatttattt
     7621 ctcacagaat ttagaaattg tgactatttt tgtcttattt gtgattggtg ctgcgactta
     7681 cggctcttta acagcggata aaaaattatt ttgaagcaag gtggatcagc tattttggcc
     7741 ttgattagta ttttactctt taaatacact tgaaggttga ttctaatctc gctaatcctt
     7801 tttaatccag aataagggaa atatgttata cttgttttta agaaaaaagt ctcattgaat
     7861 tggttttgag gagttagaaa tgaaagtatt agtgacaggt tttgagccct tttgaggcca
     7921 ttaaaggttt accagctgaa atccatggtg ctgaggtccg ttagctagag gtgccgacag
     7981 tttttcacaa atctgctcaa gtattggaag aagagatgaa tcgttatcaa cctgactttg
     8041 tcctttgtat tgggcaagct ggtggaagaa ctagtttgac acctgaacga gtggccatta
     8101 atcaagacga tgcacgcatt tctgataacg aagataatca accgattgac cgtcccattc
     8161 gcccagatgg tgcttcggcc tactttagta gtttgccgat taaagcgatg gttcaagcta
     8221 taaaaaagag ggcttaccgg cctctgtttc caatacggca gggacttttg tctgcagcca
     8281 tttgatgtat caggctctct atttggtaga aaagaaattt ccatatgtta aggcaggttt
     8341 tatgcatatt ccttatatga tggaacaggt ggtgaacaga cagactattc cagctatgag
     8401 tttagtggat attcggagag ggatagaagc agcaatcggc gctatgatag aacatggaga
     8461 tcaggaactc aagttggtag gcggagaaac tcattgatag aaaaaagctt gagtggaaaa
     8521 accttcaagc ttttggacgt tttcgagcca atactgctcg gtaaaacata attttagtgc
     8581 attggatata aggtaggagt gaaaaactag caatgccaaa ggtaatccaa ttgaggaagt
     8641 accaaggaag aagctgtaaa tctaggacaa agcgctggaa cttgtagccc ttcataaagg
     8701 aacggctagt ttttaggatt cgtcttggtg ggacctgtcc taggtctaga ctataacaga
     8761 gaagaaattc cacctgtgaa taggcataat actgtggaat atagaggata tttcctacaa
     8821 tgatcaagat gagacttgca agaaagtaga gtccaaagac catgaggaaa cgctcggttt
     8881 caactgatga gagatctaga tttggaaact caggatgtag ggtgacgaat tttttggcta
     8941 aaaagctact ataaaagagg aggtaaatcc caagtaaatt agggatactc cataaaaaga
     9001 gatagaaacg tttgagaagt agggtcaaaa aggtttgaga aaagcgctcc tcatcaaaga
     9061 gagctaggct gttttttaca gatggctccg ttttagaatc tttcatgagt gtcagtgttg
     9121 catagacgga actggtcaaa agaatagtcc cgataaagaa gactagtaga ggaaagaggt
     9181 aggcttgaag tatttggcca agtatgctga aaaatggctg ttctaaaaca gtcccgtgga
     9241 tccgagataa gggattaaga aaactagata agatgaccag catactggga aggatataga
     9301 ggagaaagag acggggggtg tcagcctgaa aatgttttga ctcctgacga attgttttta
     9361 aatcaatttt tggatagttc attctcttat tataccatag ttcttataca tagttcgtga
     9421 cagttcctac tttttttgat aaaatcatac agtgtgtcct tgggcacact gtatgaactg
     9481 ggactgtctt tcccagcttc ggaggtaaaa aatgtcagat tcaccaatca aatatcgttt
     9541 gattaagaaa gaaaaacaca caggagctcg tctgggagaa atcatcactc cccacggtac
     9601 ctttccgaca cctatgttta tgccagttgg gacacaagcc actgtcaaaa ctcagtcacc
     9661 tgaagaattg aaggagatgg gttcgggaat tatcctatca aacacctatc atctctggct
     9721 tcgccctgga gatgaactca ttgcacgcgc tggtggtctc cacaagttca tgaattggga
     9781 ccagcctatc ttgacagata gtggtggttt tcaggtttat tctttagcag atagccgtaa
     9841 tatcacagaa gaaggagtaa cctttaaaaa tcatctaaat ggttctaaga tgttcctatc
     9901 cccagaaaaa gccatctcta ttcagaataa tctgggttca gacatcatga tgtcctttga
     9961 tgaatgtcct cagttttatc aaccttatga ctacgttaag aaatcgatcg agcgtaccag
    10021 ccgttgggct gagcgtggtt tgaaggctca ccgtcgtcca catgaccaag gtttgtttgg
    10081 aattgtgcaa ggtgcaggat ttgaagacct tcgccgccaa tcagctcatg atcttgtcag
    10141 catggatttc tcaggctact ctatcggtgg tttggcagtg ggagaaaccc atgaagagat
    10201 gaatgcggtc ttggacttta caactcaact gctacctgaa aataaacctc gttatctgat
    10261 gggtgtggga gcgccagata gcttgatcga tggggtcatt cgtggggtgg atatgtttga
    10321 ctgtgtctta ccgactcgaa ttgctcgtaa cgggacttgt atgaccagtc aaggacgttt
    10381 ggttgtgaaa aatgcccagt ttgctgagga ctttacgcca ctggatcctg agtgtgactg
    10441 ctacacatgt aataactata cacgcgctta ccttcgtcac ctgctcaagg ctgatgaaac
    10501 ctttggtatc cgcttgacta gctaccacaa tctttacttc ttgcttaacc tgatgaagca
    10561 agtgcgacaa gccatcatgg atgacaatct cttggaattc cgtgagtatt ttgtggaaaa
    10621 atatggctat aataagtcag gacgtaattt ctaaaatgga attgatataa aaaaatccta
    10681 agttttctct taggattttt cttctttttt tgatagaata aagtgtacaa tgaaaggaag
    10741 aataaactcg tatgcgcatt aaatggtttt ccttgattag gattataggt ttacttttgg
    10801 tactcttgta tcacttcttt cagacgatct ttcctggagg attcttcggg gtagatgtct
    10861 ttttcacatt ttcaggtttc ctgattacag ctctactcat tgaagaattt tctaagaaca
    10921 atgagattga tttgatagga ttttttagaa gacgctttta tcggattgtg ccacctgtgg
    10981 ttttgatggt cttggtgacc atgcctttta ctttcttggt tcgccaagac tatgttgctg
    11041 gaattggtgg ccagattgcg ggcgtcttag gctttatgac caacttctat gaactcctaa
    11101 caggtgggag ttatgaatct cagttcattc ctcatttgtt tgttcataat tggagtttgg
    11161 cagttgaggt tcactactat attctttggg gattggcagt ttggttctta tccaaacaag
    11221 ctaaatcaaa tggtcagttg aaggggatgg tctttctctt atctgctgct gccttcttga
    11281 tcagtttctt ctccatgttt attggtagtt ttctagtgac ctcttattcc tctgtttatt
    11341 tctccagttt aactcatgtc tatccattct ttttgggaag tatgttagca actattgtag
    11401 gcgttcgtca gacgacttcc ctcgtcaagc agttggataa aatctgggat ttacgaaaga
    11461 ctttggtagt ttttggagga ggctttggtt tcctagttct tttgactttc tttgtcaaat
    11521 tcacttatct ttttgcctat cttatcggct tcttgcttgc cagtcttgca gctcttgcca
    11581 tgattctggc ggcgcgtgtc ttacatgaaa agacacatca tatacaggag ccgaagatta
    11641 tcagcttttt agcggatact agctatgcgg tttatctttt ccattggcct ttctatatca
    11701 ttttctcaca gttgacatca aatcttcttg ctgtattact gactctgatt tgttcttatg
    11761 gctttgccag tctgtcattc tatgtattgg aaccttggat tgcaggcaag aacacaccta
    11821 ttttacaaac tcttcgtccc ctgccttata ttcacgcaat tcttgcagca ggtacaggaa
    11881 tcttgacctt cattgtctgc atggtgacct tgttggcacc acaagtggga gcgtttgaga
    11941 cagacttgac tgtcaatggc ttgaagcaag ctgcaacaaa tattggccag accaaggtga
    12001 tggcagaacg ggcagatgca aacagtttgg gaattgctga tggcactatg ttaattggtg
    12061 actcagtggc tttaagggca aatacagcac tacagacagt tcttcctgga gcacagatta
    12121 acgcgcaggt cagcgtaaca accaagaccg caaatgaaat catgctaaat aatagccaga
    12181 ataaattttt acctaagacg gtggtcattg cgactggggt aaataatcct gagaattaca
    12241 aggatgactg ggacagtatc gtgaaaaatc ttcctaaggg acaccatatg attttggtga
    12301 ctccttatga gggagataag acaaaagaga cctatgccat cgttgagaag gctgctgcct
    12361 atatgagaga attggcagag aagacacctt acattacgat agcagattgg aatcaagttg
    12421 cgaaagagca tccagaaatt tgggcaggaa cagaccaggt tcatttcggg agtgagagta
    12481 gcactatcga agcaggagca aaattgtatg cagatacgat tgccacagct ttgcagacag
    12541 ctcaagacaa gccggttaaa tcaaaataac ttgtattaaa aaagagaaga gttggagaaa
    12601 tccagctctt ttaaaatatc tccaaaaaat aggtctatac catttacaaa taaaaaagaa
    12661 aggtttataa tgtaattgac ataataaatt gtagaatcaa tcttttaagg aggttaacat
    12721 tatgcctaac tatattaaag cggatcagtt tttctaccca cacggagttc gtcgaggtgg
    12781 ttacttggaa cttgtggacg gcaagtttgg gaaacatgta gagcagattc ctgaaggggc
    12841 tgaggtgatt gactatacag gttatagcat tgccccaggt cttgtggata ctcatattca
    12901 tggatatgca ggtgtagatg tgatggacaa caacattgaa ggtacattgc atactatgag
    12961 tgaaggactt cttagtaccg gtgttaccag tttcttaccc acaactttaa cagccactta
    13021 tgagcaattg cttgcagtca ctgaaaatct tggaaaccat tataaagaag caacaggtgc
    13081 taagattcgt gggatttatt atgaaggtcc atatttcaca gaaactttta agggggcaca
    13141 aaatccaact tatatgagag acccgggtgt tgaggagttt cattcttggc aaaaagcggc
    13201 aaatggcttg cttaataaaa ttgcccttgc accagaacgt gatggggtgg aagactttgt
    13261 tcgtacagtt acgggcgaag gtgtgacggt tgctcttgga cattcaaacg cgacttttga
    13321 tgaagccaaa aaagcagtcg atgctggagc gagtgtttgg gtgcatgcct acaatggaat
    13381 gcgtgggttg actcaccgtg aattgggtat ggttggagcc atgtaccaat tgccacatac
    13441 ctatgcagag ttgatctgtg atggtcacca cgtagatcca aaggcttgcg aaattcttat
    13501 caaacaaaaa ggaacagaaa acatcgctct tatcacagac tgtatgacag ctgggggatt
    13561 ggaagacgga gattatatgt tgggagaatt cccagttgtc gttgcaaatg gaactgcacg
    13621 cctcaaatcg acaggtaact tggcaggttc tatcctcaaa ctcaaagatg gtttgaagaa
    13681 tgtggtcgaa tggggaattg cgaatccgca tgaagcagtc atgatggcca gcttcaaccc
    13741 agctaaatcc gttcacatcg atgacgtctg tggccaaatc cgtgaaggct acgacgctga
    13801 cttcatcgta ttagataaag atttggaatt ggtagcaacc tacctagatg gcgtgaaacg
    13861 ttatcaagca taagagagaa agcagaagtt agagactaac ttctgctttt ttatgcaggg
    13921 tactttactg gtaaataaaa agttaaaaaa atcacaaaaa aagcttgaag aaacaaagaa
    13981 aaaggcttac aattgaacta taaatattac aaataaaaaa acggaggagt gctttatgaa
    14041 agcttatact tatgttaaac caggacttgc ttcttttgtt gatgtagaca aaccagttat
    14101 tcgcaagcca acagacgcta ttgtgcgtat tgtaaaaacc actatttgtg gaacagacct
    14161 ccatattatc aaaggggatg ttcctacttg ccaaagtggt accattcttg gccacgaagg
    14221 gattgggatt gttgaagaag ttggggaagg agtttccaac ttcaaaaaag gtgacaaggt
    14281 cttgatttct tgcgtctgtg cctgtggtaa atgctactac tgtaaaaaag gaatttatgc
    14341 ccactgtgaa gacgaagggg gctggatttt cggtcacttg attgatggta tgcaggctga
    14401 atatctacgt gtccctcatg cagataatac tctttaccat actccagaag acttgtcaga
    14461 tgaagctttg gttatgctgt cagacattct gcctactgga tatgaaattg gtgtcttaaa
    14521 agggaaagta gaacctggtt gcagcgtagc cattattggt tcaggtccag ttggattggc
    14581 tgctctttta acagcccaat tctattcacc agctaaattg attatggtag acctagacga
    14641 taaccgtttg gaaactgccc tatcattcgg tgcgactcat aaggtaaact cttcagaccc
    14701 tgaaaaagcg ataaaagaaa tttatgattt gacagatggt cgcggtgtag atgtcgctat
    14761 tgaagctgta gggattcctg aaacatttga tttctgtcaa aagattatcg gtgtagacgg
    14821 aacggttgcc aactgtggtg tgcatggtaa accagttgaa ttcgatttag ataaactttg
    14881 gattcgtaac atcaatgtaa caactggttt ggtatctaca aatacgactc cacaattgtt
    14941 gaaagcactt gaaagtcata agattgaacc ggaaaaattg gtaactcact atttcaaact
    15001 cagtgaaatt gaaaaagcct acgaagtctt cagtaaggca gcagaccacc atgccattaa
    15061 ggtcattatc gaaaacgata tctcagaagc ctaagtagta aaaatatttt tgtacataag
    15121 caaatagaaa ttcagtcatc catcagatgg ctggattttt tatcaaaaaa ttaagaaatg
    15181 agcatatttc tttccttgtc tggcggaatt ggttataata tacggtacaa aggaatgaat
    15241 gaatatgtat cgtgttatag aaatgtacgg agattttgaa ccgtggtggt tcttagaagg
    15301 ttgggaagaa gatattgtag caagtagaaa atttgaccag tattatgatg ctctcaaata
    15361 ctacaaaact tgctggttta gattagaaca agaatcccct ctttataaaa gtagaagcga
    15421 cttgatgacc attttttggg acccggaaga ccaacgctgg tgtgatgaat gtgatgagta
    15481 tttacaacaa taccattctt tggctctttt gcaggatgag caggttatcc cagacgaaaa
    15541 actacgctca ggctatgaaa aacaaaccag tcaggaaagg aatcgttctt gccgtatgaa
    15601 attaaaatag agaaaagtaa cttttttgga gttgcttttt ttatttttct aacgctttgc
    15661 gaatagtata ggtgaggagg taagtatggt tcaagaaatt gcacaagaaa tcattcgttc
    15721 ggctcggaaa aaaggggcgc aagacattta ttttgtccct aagttagatg cctatgagct
    15781 tcatatgagg gtaggagacg agcgctgtaa aattggtagc tatgattttg aaaagtttgc
    15841 agccgttatc agtcacttta agtttgtggc gggtatgaat gtgggagaaa aaagacgtag
    15901 tcaactgggt tcctgtgatt atgcctatga ccagaagatg gcgtctctac gtttatctac
    15961 tgtaggcgat tatcgggggc atgagagttt ggttatccgt ttgttgcacg atgaggagca
    16021 ggacttgcat ttttggtttc aggatattga agaattaggc aagcagtaca ggcaacgggg
    16081 actctatctt tttgctggtc cggttgggag tggtaagacg accttgatgc atgaattgtc
    16141 caagtcactc tttaaaggac agcaagttat gtccatcgaa gatcctgtcg aaatcaagca
    16201 ggacgacatg cttcagttgc agttgaacga agcaatcggc ctaacctatg aaaatctaat
    16261 caaactttcc ttgcgtcatc gaccagatct cttgattatc ggagaaattc gtgacagcga
    16321 gacggcgcgt gcagtggtca gagctagttt gacaggtgcg acagtctttt caaccattca
    16381 cgccaaaagt atccgaggtg tttatgagcg tctgctggag ttgggtgtga gtgaagaaga
    16441 attggcagtt gttctgcaag gagtctgcta ccagagatta atcgggggag gaggaatcgt
    16501 tgactttgca agcagagatt atcaagaaca ccaagcagcc aagtggaatg agcaaattga
    16561 ccagcttctt aaagatggac atatcacaag tcttcaggct gagacggaaa aaattagcta
    16621 cagctaagca aaaaaatatc atcaccctat ttaacaatct cttttctagc ggttttcatc
    16681 tggtggagac catctccttt ttagatagga gtgctttgtt ggacaagcag tgtgtgaccc
    16741 agatgcgtgt gggcttgtct caggggaaat cattctcaga aatgatggaa agtttgggat
    16801 gttcaagtac cattgtcact cagttatctc tagctgaagt tcatggcaat cttcacctga
    16861 gtttgggaaa gatagaagaa tatctagaca atctggccaa ggtcaagaaa aagttaattg
    16921 aagtagcgac ctatcctttg attttgctgg gttttcttct cttaattatg ctggggctac
    16981 ggaattacct gctcccacaa ctggatagta gcaatattgc cacccgaatt atcggtaatc
    17041 tgccacaaat ttttctaggc atggtagggc ttgtttccgt gcttgccctt ttagcactaa
    17101 ctttttataa aagaagttct aagatgagtg tcttttctat cttagcacgc cttcccttta
    17161 ttggaatctt tgtgcagacc tacttgacag cctattatgc acgtgaatgg gggaatatga
    17221 tttcacaggg aatggagctg acgcagattt ttcaaatgat gcaggaacaa ggttcccagc
    17281 tctttaaaga aatcggtcaa gatctggctc aaaccctgaa aaatggccgt gaattttctc
    17341 agacgatagg aacctatcct ttctttagga aggaattgag tctcatcata gagtatgggg
    17401 aagttaagtc caagctgggt agtgagttgg aaatctatgc tgaaaaaact tgggaagcct
    17461 tttttacccg agtcaaccgc accatgaatt tggtgcagcc actggttttt atctttgtgg
    17521 cactgattat cgttttactt tatgcggcaa tgctcatgcc catgtatcaa aatatggagg
    17581 taaattttta aaatgaaaaa aatgatgaca ttcttgaaaa aagctaaggt taaagctttt
    17641 acattggtgg agatgttggt ggtcttgctg attatcagcg tgcttttctt gctctttgta
    17701 cctaatctga ccaagcaaaa agaagcagtc aatgacaaag gaaaagcagc tgttgttaag
    17761 gtggtggaaa gccaggcaga actttatagc ttggaaaaga atgaagatgc tagcctaagc
    17821 aagttaaaag acgatgggcg aatcacggaa gaacaggtta aagcttataa agaatacaat
    17881 gataaaaatg gaggagcaaa tcgtaaagtc aatgattaag gcctttacca tgctggaaag
    17941 tctcttggtt ttgggtcttg tgagtatcct tgccttgggc ttgtccggct ctgttcagtc
    18001 cacttttgcg gcagtagagg aacagatttt ctttatggaa tttgaagaac tctatcggga
    18061 aacccaaaaa cgcagtgtag ccagtcagca aaagactagt ctgaacttag atgggcagat
    18121 gattagcaat ggcagtcaaa agttgccagt ccctaaagga attcaggccc catcaggcca
    18181 aagtattata tttgaccgtg ctgggggcaa ttcgtccctg gctaaggttg aatttcagac
    18241 cagtaaagga gcgattcgct atcaattata tctaggaaat ggaaaaatta aacgcattaa
    18301 ggaaacaaaa aattagggca gtgattttac tggaagcagt agtcgctcta gctatctttg
    18361 ccagcattgc gaccctcctt ttgggacaaa ttcaaaaaaa taggcaagag gaagcaaaaa
    18421 tcttgcaaaa ggaagaagtc ttgagggtag ctaagatggc cttgcagacg gggcaaaatc
    18481 agataaacat caacggagtt gagattcagg tattttctag tgaaaaagga ttggaggtct
    18541 accatggttc agaacagttg ttggcaatca aagagccata aggtcaaggc ttttaccttg
    18601 ttagaatccc tgcttgccct gcttgtcatc agtgggggct tactcctttt tcaagctatg
    18661 agtcagctcc tcatttcaga agttcgctac cagcaacaaa gcgagcaaaa ggagtggctc
    18721 ttgtttgtgg accaacttga ggcagaatta gaccgttcgc agttcgaaaa agtagaaggc
    18781 aatcgcctat acatgaagca agatggcaag gacatcgcca tcggtaagtc aaagtcagac
    18841 gattttcgta aaaccgatgc tagtggacga ggttatcagc ctatggttta tgggctcaaa
    18901 tccgcacaga ttacagagga caatcaactg gtgcgctttc gtttccagtt tcaaaaaggc
    18961 ttagaaaggg agttcatcta tcgtgtggaa aaagaaaaaa gttaaggcag gtgttctcct
    19021 ctacgcagtc accatagcag ccatctttag tcttttgttg caattttatt tgaaccgaca
    19081 aatcgcccac tatcaagact atgctttaaa taaagaaaaa ttggttgctt ttgccatggc
    19141 taaacgaacc aaggataaag ccgagcaaga aagtggggaa caggtcttta atctaggtca
    19201 ggtaagctat caaaacaaga aaacaagctt ggtgacgact gttcgtacgt ctaagagcca
    19261 atatgagttt ctgtttcctt cagtcaaaat caaagaagag aaaagagata aaaaggaaga
    19321 ggtagcgacc gattcaagcg aaaaagtgga gaagaaaaaa tcagaagaga agcctgaaaa
    19381 gaaagagaat tcctagtcaa ttcaactata atgcgttgaa tccagaatag ttcactgtag
    19441 tttctagaaa attgctggaa atggatgtta agctccaatt tatttgttta tatcttattt
    19501 cagtttacta tactttgtgc taaactaaag atatgaaaca tgattttaac cacaaagcag
    19561 aaactttcga ttcccctaaa aatatcttcc tcgcaaactt ggtatgtcaa gcagtcgaga
    19621 aacagattga tattttatca gacaaagaaa ttttagattt cggtggtggc acgggtctat
    19681 tagccttgcc cctagccaag caggctaagt cagttactct tgtagacatt tctgagaaaa
    19741 tgttggagca agctcatttg aaagcggagc agcaagcaat caagaatatc cagtttttgg
    19801 agcaagattt accgaaaaat cccttggaga aagagtttga ttgccttgct gttagtcggg
    19861 ttcttcatca tatgcctgat ttggatgcgg ctctctcact gtttcatcaa catttgaagg
    19921 aagatgggaa actcatcatt gctgatttta ccaagacaga agctaatcat catggatttg
    19981 atttagctga actggaaaac aagctaattg agcatggttt ttcatctgtg catagtcaga
    20041 ttctctatag cgctgaagac ttgtttcaag gaaatcactc agaattcttt ttaatagtag
    20101 cccaaaaatc actcgcctag tcagggagtg atttttctat aaggatggaa aaaagaaggg
    20161 aaatttgata agataggaat atggattttg aaaaaattga acaagcttat acctatttac
    20221 tagagaatgt ccaagtcatc caaagtgatt tggcgaccaa cttttatgac gccttggtgg
    20281 agcaaaacag catctatctg gatggtgaaa ctgagctaaa ccaggtcaaa gacaacaatc
    20341 aggcccttaa gcgtttagca ctacgcaaag aagaatggct caagacctac cagtttctct
    20401 tgatgaaggc tgggcaaaca gaacccttgc aggccaatca ccagtttaca ccggatgcta
    20461 ttgctttgct tttggtgttt attgtggaag agttgtttaa agaggaggaa attactatcc
    20521 tcgaaatggg ttctgggatg ggaattctag gcgctacttt cttgacctcg cttgataaaa
    20581 aggtggatta cttgggaatg gaagtggatg atttactgat tgatctggca gctagcatgg
    20641 cagatgtaat tggtttgcag gctggctttg tccaaggaga tgccgttcgt ccacaaatgc
    20701 tcaaagaaag cgatgtggtc atcagtgact tgcctgtcgg ctattatcct gatgatgccg
    20761 ttgcgtcgcg tcatcaagtt gcttctagcc aagaacatac ttacgcccat cacttgctca
    20821 tggaacaagg atttaagtac cttaagtcag atggatatgc tatttttcta gctccgagtg
    20881 atttgttgac cagtcctcaa agtgatttgt tgaaagtctg gttgaaagag gaggcaagtc
    20941 tggttgctat gattagtctg cctgaaaatc tctttgctaa tgctaaacaa tctaagacta
    21001 tttttatcct acagaagaaa agtgaaatag cagtggagct ttttgtttat ccacttgcta
    21061 gcttgcaaga tgcaagtgtt ttaatgaaat ttaaagaaaa ttttcaaaaa tggactcaag
    21121 gtactgaaat ataaaataga ttttgttata atagttgaaa acgcttaaaa aggggtatca
    21181 tgttatgaca aaaacaattg caatcaatgc aggaagttca agcttaaaat ggcaattata
    21241 cttaatgcca gaggaaaaag tattggcgaa aggcttgatt gaacgtatcg gtttgaaaga
    21301 ttcaatttca actgtaaaat ttgacggccg ttctgaacaa caaattttgg atatcgaaaa
    21361 tcatacacaa gccgttaaaa ttttattgga tgacttgatt cgtttcgata ttatcaaggc
    21421 ttatgacgag attacaggtg ttggccaccg tgttgtagca ggtggagaat atttcaaaga
    21481 atcaacagtt gttgagggag atgttttaga aaaagttgaa gagttgagtt tgttggctcc
    21541 tctacacaac ccggccaatg cagcaggtgt tcgtgccttc aaggaattgt tgccagacat
    21601 taccagtgta gttgtttttg atacttcctt ccacacaagt atgccagaga aagcttatcg
    21661 ctaccctcta ccaacaaaat attacacaga aaacaaggtt cgtaaatacg gtgctcatgg
    21721 tacaagtcac cagtttgtag caggagaagc tgcaaaactc ttgggacgtc cattagaaga
    21781 cttgaagtta attacctgtc atattggtaa cggaggctca attacagctg tgaaagccgg
    21841 caaatctgta gacacttcta tggggttcac tcctcttggt ggtattatga tgggaacgcg
    21901 tacaggggat attgatccag ctatcattcc ttatttaatg caatatacag aggattttaa
    21961 cacaccagaa gatatcagtc gtgttcttaa ccgtgaatca ggtcttttgg gagtttctgc
    22021 taattctagc gatatgcgcg atatagaagc agctgtagca gaagggaatc acgaggctag
    22081 cttggcttat gaaatgtatg ttgaccgtat ccaaaaacat atcggtcagt accttgcagt
    22141 gctaaatgga acagatgcca ttgttttcac agcaggtgtc ggtgaaaatg cagagaattt
    22201 ccgtcgtgat gtaatctcag ggatttcgtg gtttggttgt gatgttgatg atgaaaagaa
    22261 tgtctttggc gttacaggag acatctcaac agaggcagct aaaatccgtg tcttggttat
    22321 tccaacagat gaagaattag tcattgcccg tgacgttgaa cgcttgaaaa aataagtgaa
    22381 actaaaaaaa tattcaatac aaggagttgg gaaagttatt tttccagctt ctttttctga
    22441 tgaaattgtc caaaaccttg ctatgattgg cttttttgaa aaatatggta taatagtagt
    22501 aatttaatag atggagttga gttttgaaga aaaactttcg tgtaaaaaga gagaaagatt
    22561 ttaaggcgat tttcaaggag gggacaagtt ttgctaatcg caaatttgtg gtctaccaat
    22621 tagaaaacca gaaaaaccat tttcgagtag gtctatcagt tagcaaaaaa ctggggaatg
    22681 ccgtcactag aaatcaaatt aagcgacgga ttcggcatat tatccagaat gcaaaaggga
    22741 gtctggtaga agatgtcgac tttgttgtca ttgctcgaaa aggagtcgaa accttgggat
    22801 acgcagagat ggagaaaaat ctactccatg tattaaaatt atcaaagatt taccgggaag
    22861 gaaatgggag tgaaaaagaa actaaagttg actagtttgc taggactgtc tctgttaatc
    22921 atgacagcct gtgcgactaa tggggtaact agcgatatta cagccgaatc ggctgatttt
    22981 tggagtaaat tggtttactt ctttgcggaa atcattcgct ttttatcgtt tgatattagt
    23041 atcggagtgg ggattattct ctttacggtc ttgattcgta cagtcctctt gccagtcttt
    23101 caggtgcaaa tggtggcttc taggaaaatg caggaagctc agccacgcat taaggcgctt
    23161 cgagaacaat atccaggtcg agatatggaa agcagaacca aactagagca ggaaatgcgt
    23221 aaagtattta aagaaatggg tgtcagacag tcagactctc tttggccgat tttgattcag
    23281 atgccggtta ttttggccct gttccaagcc ctatcaagag ttgacttttt aaagacaggt
    23341 catttcttat ggattaacct tggtagtgtg gatacaaccc ttgttcttcc gattttagca
    23401 gcagtattca cctttttaag tacttggttg tccaacaaag ctttgtctga gcgaaatggc
    23461 gctacgactg cgatgatgta tgggattcca gtcttgattt ttatctttgc agtttatgcg
    23521 ccaggtggag tcgccctata ctggacagtg tctaatgctt atcaagtctt gcaaacctat
    23581 ttcttgaata atccattcaa gattatcgca gagcgcgagg ccgtagtaca ggcacaaaaa
    23641 gatttggaaa atagaaaaag aaaagccaag aaaaaggctc agaaaacgaa ataaataagg
    23701 aggaatctgg taatggtagt atttacaggt tcaactgttg aagaagcaat ccagaaagga
    23761 ttgaaagaat tagatattcc aagaatgaag gctcatatca aagtcatttc tagggagaaa
    23821 aaaggctttc ttggtctatt tggtaaaaaa ccagcccaag tggatattga agcgattagt
    23881 gaaacgactg ttgtcaaagc aaatcaacag gtagtaaaag gcgttccgaa aaaaatcaat
    23941 gatttgaacg agcctgtgaa gacggttagt gaagaaaccg ttgaccttgg tcatgtagtt
    24001 gatgctatta aaaaaataga ggaagaaggt caaggtattt ctgatgaagt caaggctgaa
    24061 atcttaaaac atgaaagaca tgccagcact atcttagaag aaactggtca cattgagatt
    24121 ttaaatgaac ttcaaatcga ggaagcgatg agggaagaag caggcgctga tgaccttgaa
    24181 actgagcaag accaagctga aagtcaagaa ctagaagact tgggcttgaa agttgaaacg
    24241 aactttgata ttgaacaagt agctacggaa gtaatggctt atgttcaaac gattattgat
    24301 gacatggatg ttgaggctac actttcaaat gattataacc gtcgtagcat caatttgcaa
    24361 attgatacta acgaaccagg tcgtattatc ggctaccatg gtaaagtctt gaaggccttg
    24421 caactgttgg ctcaaaatta tctttacaac tgctattcaa gaaccttcta tatcactatt
    24481 aatgtcaatg attatgttga acaccgtgca gaagtcttgc agacctatgc gcaaaaattg
    24541 gcgattcgtg ttttagaaga aggacgcagt catcaaacag atccaatgtc gaatagtgaa
    24601 cgcaagatta tccaccgtat tatttcacgt atggatggcg tgaccagtta ctctgaaggt
    24661 gatgagccaa atcgctatgt cgttgtagat acagaataag taaaatcagg gttgacctga
    24721 ttttttgcta gctagaggag gttaaactga tgttgaataa gataagagac tatctagact
    24781 tttctggttt gcagtaccgt agtcctgata aagcgggagc agagcgagag aagatgctgg
    24841 cattccgtca caaaggacaa gaggcccgaa aggcttttac agaactggcc aaagcctttc
    24901 aagcaagcca tccagaatgg caactccaac agactagtca gtggatgaat caggcccagc
    24961 gtttgagacc acatttttgg gtttatctac agagagacgg acaagtgaca gaacctatga
    25021 tggccttacg tttgtatggg acatctactg actttggaat ttctttggaa gtcagtttca
    25081 tcgaacgtaa gaaggatgag caaactttag agaaacaggc caagatttta gacattccaa
    25141 ccgttaaagg aatttattat ctagcctact ctgatggcca aagtcaacgg tgggaggcga
    25201 acgaagaaaa gcgtcgtact ttacgcgaga aggtgagaag tcaagaagtt cgaaaagttt
    25261 tagtgaaggt agatgttcct atgacagaaa attcgtctga agaagaaatc gtagaaggct
    25321 tattgaagtc ttattctaaa attcttccct attatctagc tacgagaaaa taagataatt
    25381 tgtaaaacat cataaatcat acagtccaag agtgaacagt ccgctgtgta attcttggtc
    25441 tttttgtttg cgctttcgca ttatataata aacttacaaa aacaattcaa aaggagaaca
    25501 attatggaag tcatttcaag tgttctaaat tggttttcta gcaatatttt gcagaatccc
    25561 gcatttttcg taggtttatt ggtgttgata ggatatgcac ttttgaaaaa acctgcccat
    25621 gacgtttttt cagggtttgt taaagcaaca gtagggtata tgttgcttaa cgtgggtgct
    25681 ggtggtttgg ttacaacctt tcgtccaatc ttagcagctc ttaactacaa attccaaatt
    25741 ggtgcagcgg ttatcgaccc ttactttgga cttgctgcag caaacaacaa aattgcagca
    25801 gagtttccag attttgttgg aactgcaact acagctctat tgattggttt tggaataaat
    25861 atcttgctcg tagctcttcg aaagattacg aaggtaagaa ccctctttat tactggtcac
    25921 atcatggtac aacaagctgc aacagtatct cttatggttc tattcttagt accacaattg
    25981 cgcaatgctt acggtacagc agcgattggt atcatctgtg gactttactg ggcagttagt
    26041 tcaaatatga ctgttgaggc aactcaacgc ttgactggtg gtggcggatt tgcgattggt
    26101 caccaacagc aatttgcaat ctggtttgta gataaagtag caggacgctt tggtaagaaa
    26161 gaagaaagtt tagacaatct taaattacct aagttcctct caatcttcca cgatacagtt
    26221 gttgcatctg ctaccttgat gctcgtattc ttcggagcca ttcttttaat cttgggtcca
    26281 gacattatgt ctaataaaga agtcatcact tcaggaactc tattcaatcc tgctaaacaa
    26341 gatttcttta tgtacattat ccaaacagcc tttaccttct cagtttactt gttcgttttg
    26401 atgcaaggtg tccgaatgtt cgtatctgag ttgacaaacg ccttccaagg tatttcaaac
    26461 aaattgttgc caggttcatt cccagcggtt gacgttgcag cttcttatgg atttggttct
    26521 ccaaatgctg tcctgtcagg atttatcttt ggtttgattg gtcaattgat tacaattgtt
    26581 ttgctcatcg tctttaaaaa tccgattctt attattacag gatttgtacc agtgttcttt
    26641 gacaatgcag ccattgcggt ctacgctgat aaacgcggcg gatggaaagc ggctgttatc
    26701 ctttccttta tatcaggtgt ccttcaagtt gctctaggag ctctttgtgt ggcccttctc
    26761 gatttggcat cttatggtgg ctaccatgga aatatcgact ttgaattccc atggcttgga
    26821 tttggatata tcttcaaata ccttggtatt gttggttatg tacttgtgtg tctcttcttg
    26881 cttgttattc ctcaacttca atttgccaaa gcaaaagata aagagaaata ttacaacggt
    26941 gaagttcaag aagaagctta gtatctagaa aaggagaaat aaaatggtta aagtattagc
    27001 agcgtgcgga aatggaatgg gttcatcaat ggttatcaag atgaaggttg aaaatgctct
    27061 ccgtaagctt aatcaaacag attttacagt caattcatgc agtgtcggtg aagctaaagg
    27121 tttagcagta ggatatgaca tcgtaatcgc ttctcttcat ttgattcaag aattggaagg
    27181 gcgaactaat gggaagttaa ttgggcttga taacttgatg gatgataaag aaatcaccga
    27241 aaaactcagt caagcactac agtaaaaggt tggagggggc tggacagaaa ctgagagtta
    27301 tcgtttctgt ccttctccct ctttaaataa aggaggcaga tatgaattta aaacaagctt
    27361 taattgacaa cgactcgatc cgactaggtt tagaggctaa cgattggaaa gaagcagtca
    27421 aggtagcagt agatcccttg attgaaagtg gggcaatttt gccagagtat tacgatgcta
    27481 tcattgaatc gactgaagag tatgggcctt actatatctt gatgccaggt atggctatgc
    27541 cccacgctag acctgaagct ggtgtgcaaa gtgatgcctt ttcattaatt accttacaaa
    27601 atcctgttgt attttcagat gggaaagagg tatctgtttt gttggcacta gcagcaacaa
    27661 gttcaaaaat tcacacaagt gtagccattc cacaaattat tgccctgttt gaattagaag
    27721 attctattgc acgtttacag gcttgccaga ctaaagaaga tgtcttggct atgattgaag
    27781 aatctaagga tagcccttat ctcgaaggat tggatttgga aagttagaaa gaggaataaa
    27841 gaaatgacaa aaagaatacc taatttacaa gttgcattag accattcaga cttgcaagga
    27901 gcgattaaag cagctgtttc tgttggtcag gaagtagata ttatcgaagc tggaactgtt
    27961 tgcttgcttc aagttggaag tgaactggct gaagtcttgc gtagcctttt cccagataag
    28021 attattgtgg cagacacaaa atgtgctgat gctggtggaa cagttgctaa aaataatgcg
    28081 gttcgtggag cagactggat gacttgtatc tgttgtgcaa ccatccctac tatggaagca
    28141 gctctaaagg ctatcaagac tgaacgagga gaacgaggcg aaatccagat cgagctttat
    28201 ggcgattgga cttttgaaca agctcagctt tggctagatg caggtatctc acaagctatt
    28261 tatcaccaat ctcgtgatgc tcttcttgct ggtgaaactt ggggtgaaaa agaccttaat
    28321 aaggttaaaa aactcattga catgggcttc cgtgtatctg taacaggtgg tctagatgta
    28381 gatactctca aactctttga aggtgttgat gtctttacct ttatcgcagg tcgtggaatt
    28441 acagaggctg tggatccagc aggagcagcg cgtgccttca aggatgaaat caaacgaatt
    28501 tgggggtaaa tcatggtacg tccaattgga atttatgaaa aggcaacccc aacacacttt
    28561 acttggctag aacgtttaaa ttttgccaag gagttaggct ttgattttat cgagatgtct
    28621 attgacgaac gtgacgagcg tttagcaaga cttgactgga gtaaggaaga acgcttggaa
    28681 gttgtcaaag aaatctatga aactggtgtt cgtattcctt ctatctgttt ttcaggccat
    28741 cgtcgctacc cattgggatc aaaagattca gttctagagg aaaaatctct agaactcatg
    28801 aaaaaatgta tcgaattagc tcaagacttg ggagttcgta cgattcaatt agctggttac
    28861 gatgtttact atgaggaaaa gtcaccccag acacgccaac gttttatcaa aaatttgaga
    28921 aaagcctgtg actgggctga agaagctcag gtggtacttg ctattgaaat tatggatgat
    28981 cctttcatca gtagcatcga aaaatatttg gctatagaaa aagagattga ctctcccttc
    29041 ctctttgtat atccagatat tggtaatgtg tctgcatggc ataatgatat ctatagtgag
    29101 ttttatcttg gtcatcatgc catcgcagct ctccatctca aggatactta tgcagtgaca
    29161 gaaagttcaa agggccagtt ccgagatgta cctttcgggc aaggttgtgt caaatgggaa
    29221 gaagctttcg atattttaaa ggaaaccaat tataatggac ctttcctaat cgaaatgtgg
    29281 tctgaaaatt gtgaaacagt agaagaaaca cgcgcagcca ttcaagaggc gcaagctttt
    29341 ctctatccac tcattaagaa agcaggtttg atgtaagatg aatcaagtaa tcaatgctat
    29401 gcgtaaacga gtctgtgatg ccaatcaatc attgccaaaa catggacttg tcaaatttac
    29461 ctgggggaat gtatctgaag ttaatcgcga actcggtgtc attgttatca aaccatcagg
    29521 cgtggattat gacgaattga cacctgaaaa catggtagtg actgatctag atggtaagat
    29581 cctagaaggg gatttaagac catcttccga cctcccaact catgtgcaat tatataaggc
    29641 ttggtcagaa attggtagtg tggttcacac ccattcgaca gaagctgttg gttgggctca
    29701 ggcaggtcgt gatattcctt tctacggaac aacccatgca gattatttct acggttcaat
    29761 cccttgcgcc cgtagtttga ccaaggacga agtagaagtg gcctatgaaa aagatactgg
    29821 cctggttatc gtagaagagt ttgaacatcg cggacttaac ccggttgaag taccaggaat
    29881 tattgtacgc aatcacggtc cattcacctg gggcaaaaat ccagagaatg ctgtttatca
    29941 ctctgtcgta ctagaggaag tatcaaagat gaatcgcttt acagaacaaa tcaatccaag
    30001 agttggacct gctccccagt acatactaga aaaacactac caacgtaaac atggaccaaa
    30061 tgcttattat ggtcaaaagt aagaacgatg aaggaggaga aaaagataaa tttagctcct
    30121 ctttttacat ttgattttta ttgagagtaa agttggaatt gaagtaattt taaaagattt
    30181 tttagaaata gcgcttgata tatatatggt aaaataaaaa gaattgctgt gatatcaata
    30241 gatttggggg attttttaat atggtactgg ataaggcaag ttgtgatttg cttcaatatt
    30301 tgatggatca agaaacgtcc aaaacgatta tggcgatttc gaaagatttg aaagagtcaa
    30361 gaaggaaaat ttattatcac attgacaaaa tcaatgctgc tctgggtgac gaggcgcttc
    30421 acatcattag tattccacga attggtattc acttaacgga agagcagaga gatgcttgtt
    30481 gtaaactatt atcggaagta gattcgtacg attatatcat gagtgcgcat gaacgtatga
    30541 tgataatgtt actatggata ggtatttcta aagaacgtat tacgattgaa aaattgatag
    30601 agttaacaga ggtatctagg aatactgttc tcaatgattt gaatagtatt cgttatcaac
    30661 taactttgga acaatatcag gtgatcttgc aagtgagcaa gtcacaggga taccaccttc
    30721 atgcccaccc tcttaataaa attcagtatc ttcaatcgct tctatatcat atttttatgg
    30781 aagaaaatgc cacttttgta tctattttag aagataagat gaaagagagg ttagatgatg
    30841 agtgtttgct ttctgttgaa atgaaccaat tttttaagga acaggttcct ttagttgaac
    30901 aagatttagg gaagaaaata aaccatcatg aaataacttt tatgttgcag gttctacctt
    30961 atttgctgtt aagctgtcat aatgttgaac agtatcaaga aagacatcag gatatagaga
    31021 aagaattttc tttgataaga aaaagaatag agtatcaggt gtctaagaaa ttaggagaac
    31081 ggttgtttca aaagtttgaa atttctttgt caggacttga agtttctctt gtagctgttc
    31141 tcctcctctc ctatcgtaaa gatttggata ttcatgcaga aagtgatgat tttcggcaat
    31201 taaaacttgc tttagaagaa tttatctggt attttgaatc acaaatccga atggagattg
    31261 agaacaagga tgatttgtta cgaaatttga tgatccactg taaagccttg ttatttagaa
    31321 agacttacgg tattttttct aaaaatcctc taacaaaaca aattcgatcc aagtatggag
    31381 aattattttt agtcactaga aaatctgcgg aaattttaga aggagcatgg tttattcggc
    31441 taacagacga tgatattgcc tatttgacga ttcatattgg aggattttta aaatatacac
    31501 catcgtctca aaaaaatatg aaaaaagttt atctcgtttg tgatgaaggt gttgcggttt
    31561 cgagactttt gctgaaacaa tgcaaacttt attttccaaa tgagcaaatt gacactgtat
    31621 ttacaacaga acaatttaag agtgtggaag atattgcaca agttgatgta gtgattacta
    31681 ctaatgatga tttggatagc agatttccga ttttaagggt taatcctatc cttgaagcag
    31741 aagatatttt gaaaatgcta gactatctta aacacaatat atttcgtaat aagagcaaaa
    31801 gtttcagtga aaatctttct agtcttattt cgtcttatat tgtagacagc aagttggcta
    31861 gtaagttcca agaagaggtt caaacactta taaatcaaga aatagtagtt caagcttttt
    31921 tggaagatat ttgaaggaca gtccaatgat gaacacaaac ctgtgttttt cttggtcttt
    31981 tttagtgttt tgaagggtgg tatactaatc tcaaagataa caattatatc caaaggaggc
    32041 aacatatgcc aaacgtcaaa gaaattacaa gagagtcatg gattttagcc actttcccag
    32101 agtggggaac atggttgaac gaagaaatcg aagaagaagt cgtacctgaa ggcaactttg
    32161 ccatgtggtg gctaggcaac tgtggtactt ggattaagac accagctggt gctaacgttg
    32221 tcatggacct ttggtcaaac cgtggaaaat caaccaaaaa agtgaaagat atggttcgtg
    32281 ggcaccaaat ggcaaatatg gcaggtgttc gtaagttgca accaaacttg cgtgttcagc
    32341 caatggttat cgatccattt gctatcaacg aactagacta ttacttagtt tcacacttcc
    32401 acagtgatca tatcgaccca tacacagctg cagcaattct caacaatcct aagttagagc
    32461 atgttaagtt tatcggtcct taccactgtg gacgaatctg ggaaggatgg ggtgttccaa
    32521 aagaacgtat catcgttgtt aaaccaggtg acactatcga attaaaagat atgaagattc
    32581 atgcagtaga atcatttgac cgtacttgct tggtaactct cccagtgaac ggtgctgatg
    32641 agacaggcgg tgaacttgct ggcttggctg ttacagatga agaaatggct caaaaggctg
    32701 ttaactatat ctttgaaaca ccaggtggaa ccatctatca tggtgcagat tctcacttct
    32761 caaactattt tgcaaaacat ggtaaagact ttaaaattga tgttgctttg aataactatg
    32821 gtgaaaatcc ggtaggtatc caagacaaaa tgacatctat cgaccttctt cgtatggcag
    32881 aaaatctgcg taccaaagtc attatcccag ttcactatga tatctggtct aacttcatgg
    32941 cttctactaa tgagattcta gaactttgga aaatgcgaaa agatcgcttg caatacgatt
    33001 tccatccatt tatctgggaa gttggcggta agtacactta tcctcaagat caacacttag
    33061 tagaatacca tcatccacgt ggttttgatg attgttttga acaagactct aacattcaat
    33121 ttaaagcttt gctataatat aaaaatattc tttggaggtt atccgtatgt tgcatgatac
    33181 ggataatttt catataatag taaaatagaa tgtgtgattc aataatcacc tcaaatagaa
    33241 aggaaattct atgtcaaatc tatctgttaa tgcaattcgt tttctaggta ttgacgccat
    33301 taataaagcc aactcaggtc atccaggtgt ggttatggga gcggctccga tggcttacag
    33361 cctctttaca aaacaacttc atatcaatcc agctcaacca aactggatta accgcgaccg
    33421 ctttattctt tcagcaggtc atggttcaat gctcctttat gctcttcttc acctttctgg
    33481 ttttgaagat gtcagcatgg atgagattaa gagtttccgt caatggggtt caaaaacacc
    33541 aggtcaccca gaatttggtc atacggcagg gattgatgct acgacaggtc ctctagggca
    33601 aggtatttca actgctactg gttttgccca agcagaacgt ttcttggcag ccaaatataa
    33661 ccgtgaaggc tacaatatct ttgaccacta tacttacgtt atctgtggag acggagactt
    33721 gatggaaggt gtctcaagcg aggcagcttc atacgcaggt ttgcaaaaac ttgataagtt
    33781 ggttgttctt tatgattcaa atgatatcaa cttggatggt gagacaaagg attcctttac
    33841 agaaagtgtt cgtgaccgtt acaatgccta cggttggcat actgccttgg ttgaaaatgg
    33901 aacagacttg gaagccatcc atgctgctat cgaaacagca aaagcttcag gcaagccatc
    33961 tttgattgaa gtgaagacgg ttattggata cggttctcca aacaaacaag gaactaatgc
    34021 tgtacacggc gcccctcttg gagcagatga aactgcatca actcgtcaag ccctcggttg
    34081 ggactacgaa ccatttgaaa ttccagaaca agtatatgct gatttcaaag aacatgttgc
    34141 agaccgtggc gcatcagctt atcaagcttg gactaaatta gttgcagatt ataaagaagc
    34201 tcatccagaa ctggctgcag aagtagaagc catcatcgac ggacgtgatc cagtcgaagt
    34261 gactccagca gacttcccag ctttagaaaa tggtttttct caagcaactc gtaattcaag
    34321 tcaagatgcc ttgaatgttg tggcagctaa attaccaacc tttctaggtg gatcagctga
    34381 ccttgctcac tcaaacatga cttatatcaa gacggatgga cttcaagacg atgccaatcg
    34441 cttgaatcgt aacattcagt ttggtgttcg tgaatttgca atgggaacaa tcttgaacgg
    34501 gatggccctt catggtggac ttcgtgtata cggtggaact ttcttcgtct tctctgacta
    34561 tgtgaaggca gctgtccgct tgtcagcctt acaaggactt cctgtgactt atgtctttac
    34621 ccatgattca atcgcagttg gggaagatgg tccgactcac gaaccagttg agcatttagc
    34681 aggtcttcgt gctatgccaa atctaaatgt tttccgtcca gcagatgcgc gtgaaacgca
    34741 agcagcttgg taccttgcag tgacaagtga gaaaacacca actgcccttg tcttgacacg
    34801 tcaaaacttg actgttgaag atggaacaga cttcgacaag gttgctaaag gtgcttatgt
    34861 tgtatatgaa aatgcagccg actttgatac catcttgatt gcgacaggtt cagaggttaa
    34921 tcttgctgtc tcagctgcta aagaattggc tagtcaaggc gaaaaaatcc gcgtagtcag
    34981 catgccatct acagatgtct ttgataaaca agatgcagct tacaaggaag aaattcttcc
    35041 aaatgcagtc cgccgtcgtg ttgcagtcga aatgggtgca agtcaaaact ggtacaaata
    35101 tgttggtctc gatggtgccg ttctaggtat tgataccttc ggagcctctg ccccagcacc
    35161 aaaagtattg gcagaatatg gctttactgt agaaaatctt gtaaaaattg ttcgaaactt
    35221 gaaataatcc taaaaatcag ggcgtaagct ctggtttttc ttaccagaaa agtaaggtac
    35281 aatcttgtaa aagtagctga aatttgatat agtagtccta tgtaaaagac aaaggagaaa
    35341 acaatgaatc caaatattac ttttttaatc atgcttgtag gtatgatggc cttgatgttc
    35401 tttatgcaac gttctcaaaa gaaacaagct caaaagcgta tggaaagctt aaataaacta
    35461 caaaaaggct atgaagtgat tacaatcggt ggactttatg gaacagtcga tgaagtagat
    35521 acggagaagg gaacaatagt tcttgacgta gatggagttt acttgacttt tgaactagct
    35581 gctatcaaga cagtattacc gctgaaagaa acagcttcac tagaaggcgc aattgaaaaa
    35641 taagacggga tcacgaactc ccgtttttct ataaaagaaa ggaaatggga tgaaaaaatt
    35701 agtctttgtc tgtctgggaa atatttgccg tagccctatg gccgagtttg ttatgaaatc
    35761 aatgacagat aactacgaaa tccaaagtcg agcaacttcc tcttgggaac atggcaatcc
    35821 gattcataag gggactcagg gaatttttca acagtatgag attctttatg acaagaacaa
    35881 gacatcgctt cagattagta aggaagattt tgaagccttt gattatatta tcggaatgga
    35941 cgcttcaaat atttctgact tacgtcagat gtgtccagta gactgtcaag ataagattta
    36001 ctcattttca tctgaaagtg ttccagaccc ttggtataca ggagattttg aagaaaccta
    36061 tcgacgtgtt caagagggct gtcaagcttg gttagaacgt ttagaaaagg agagttaagg
    36121 tggaaaatct tacgaatttt tacgaaaagt atcgtgtcta tctgactcgt ccacgtttag
    36181 agcttttggc agtagttacc attgttttct gtgctgtact cgtctttttt ctaaatattc
    36241 caggaaaagg tgtcttaaaa ctcgataatg gaacgattgt ttatgatggc agtcttgtcc
    36301 gtggtaaaat gaatggtcaa ggtaccatta ccttccaaaa tggagaccaa tatacaggtg
    36361 gcttcaacaa tggagccttc aacggaaaag gtacctttca atctaaagaa ggctggacct
    36421 acgaaggtga ttttgtaaat ggtcaggctg aaggaaaagg gaaactaaca acagaacaag
    36481 aagtcgttta tgaaggaact tttaaacaag gcgtttttca acaaaaataa agcctcctta
    36541 tccaaaggag gtattattag aaccacaagg taagcgctta cctgtaaatc cctttctttc
    36601 caaatccctc ttccaagcaa gtttgtgaaa taaaaaatat ttgaaataaa tttcacaaac
    36661 ttcaaagata aaacctgata agaaaagaaa atgagaaaag tttcacaaga gtttaaaaat
    36721 tctttgtgaa atgtttatga aactgtttac aaagttgaaa taatgcgtta taataaactt
    36781 gtgaaaaaat taacaaagga tatcgttcct tgaaagctat ggaggaaaat atggctgata
    36841 aaaaaactgt gacaccagag gaaaagaaac tcgttgctga aaaacacgta gatgagttgg
    36901 ttcaaaaagc tctagttgcc cttgaagaaa tgcgtaaatt ggatcaagag caagttgact
    36961 acatcgttgc taaagcatca gtagcagctt tggatgccca cggagaattg gctttacatg
    37021 cctttgaaga aacaggacgt ggtgtatttg aagataaagc aactaagaac ttgtttgcct
    37081 gtgaacacgt agtaaacaac atgcgtcaca ctaagacagt tggcgttatc gaagaagacg
    37141 atgtaacagg attgactctt attgctgaac cagttggtgt tgtttgtggt attactccaa
    37201 caacaaaccc aacatcaaca gcaatcttca aatcattgat ttcattgaag acacgtaacc
    37261 caatcgtctt tgccttccat ccatcagcac aagaatcatc tgctcatgca gctcgtatcg
    37321 tccgcgatgc agctatcgca gctggtgctc ctgaaaactg tgtgcaatgg attactcaac
    37381 catctatgga agcaacaagt gcccttatga accacgaagg tgttgcgaca atccttgcaa
    37441 caggtggtaa tgccatggtt aaggcggctt attcatgtgg taaaccagct cttggggtag
    37501 gtgccggaaa cgttccagct tatgttgaaa aatcagcaaa cattcgtcaa gcagcacacg
    37561 atatcgtcat gtctaaatca tttgataacg gtatggtctg tgcatctgaa caagcagtta
    37621 tcattgataa agaaatttac gatgaatttg tagcagagtt caaatcttac cacacttact
    37681 ttgtaaacaa aaaagaaaaa gctcttcttg aagagttctg cttcggcgtc aaagcaaaca
    37741 gcaaaaactg tgctggtgca aaattgaacg ctgacatcgt tggtaaacca gcaacttgga
    37801 ttgcagaaca agcaggattt acagttccag aaggaacaaa cattcttgct gcagaatgta
    37861 aagaagttgg cgaaaatgag ccattgactc gtgaaaaatt gtcaccagtt attgcagttt
    37921 tgaaatctga aagccgtgaa gatggtatta ctaaggctcg tcaaatggtt gaatttaacg
    37981 gtcttggaca ctcagcagct atccacacag ctgacgaaga attgactaaa gaatttggta
    38041 aagctgttaa agctattcgt gttatctgta actcaccttc tacttttggt ggtattgggg
    38101 acgtttacaa tgccttcttg ccatcattga cacttggatg tggttcttac ggacgcaact
    38161 cagttgggga taacgttagt gccattaacc tcttgaatat caaaaaagtc ggaagacgga
    38221 gaaataacat gcaatggatg aaacttcctt caaaaacata ctttgaacgt gattcaattc
    38281 aataccttca aaaatgtcgt gacgttgaac gtgtcatgat cgttactgac catgccatgg
    38341 tagagcttgg tttccttgat cgtatcatcg aacaactgga ccttcgtcgc aataaggttg
    38401 tttaccaaat ctttgcggat gtagaaccgg atccagatat cacaactgta aaccgtggta
    38461 ctgagattat gcgtgccttc aaaccagata ccatcatcgc actcggtggt gggtctccaa
    38521 tggatgctgc caaagtaatg tggctcttct acgagcaacc agaagtggac ttccgtgacc
    38581 ttgtccaaaa attcatggat atccgtaaac gtgccttcaa gttcccattg cttggtaaga
    38641 agactaaatt catcgcgatt ccaactacat ctggtacagg atctgaagta acaccatttg
    38701 ccgttatctc tgataaagca aacaaccgta aatacccaat cgctgactac tcattgacac
    38761 caactgtggc aatcgtagat cctgctttgg tattgacagt tccaggattt gttgctgctg
    38821 atactggtat ggacgtattg actcacgcga cagaagcata cgtatcacaa atggctagtg
    38881 actacactga tggtttagca cttcaagcca ttaaattggt ctttgaaaat ctcgaaagct
    38941 cagttaagaa tgcagacttc cactcacgtg agaaaatgca taacgcttca acaatcgctg
    39001 gtatggcctt tgccaatgcc ttcctaggta tttctcactc aatggcccat aagattggtg
    39061 cgcaattcca cacaatccac ggtcgtacaa atgccatctt gcttccatac gttatccgtt
    39121 acaacggtac acgtccagct aagacagcaa catggcctaa gtacaactac taccgtgcag
    39181 atgaaaaata ccaagatatc gcacgcatgc ttggacttcc agcttctact ccagaagaag
    39241 gggttgaatc ttacgcaaaa gctgtctacg aactcggtga acgtattggg atccaaatga
    39301 attttagaga ccaaggaatt gacgaaaaag aatggaaaga acattctcgt gaattagcct
    39361 tcctggctta tgaagaccaa tgttcaccag ctaacccacg tcttccaatg gtagaccata
    39421 tgcaagaaat catcgaagat gcatactatg gctacaaaga aagaccagga cgccgtaaat
    39481 aattgtttat cagtctagaa gcaagacaaa aactcaattt gagggaaaga tccagtaatt
    39541 tttctatgat aaaaggcatc ctatcaaggt ttttgaacac ctgataggat gcctttttat
    39601 gatattgagg cctttttgcc ctttttgaaa aactagaata gaaacaaaat atataataga
    39661 ttgaaactag aatagtacac atctgcttct aaaacattgt tagaattcga tttgactgtc
    39721 ctgatcgatt tgtcctgttc ttatttcatt ttgatatata aaaaatatag tatagtagac
    39781 tgaatctaaa atagtacgaa acaattgcta aaacatttat agaaattaat tttactttcc
    39841 tgatagagtt gttcacatct tatttcaatt cactatagtt taatttaaga gtagtattta
    39901 ctaaggccca attaaaatca aagagcaaac gagaaaacga tgacaaggtg tgttgctttt
    39961 tgatttctaa agagtataat gatagatctc tataaaataa gtgcgaagga aatgagcttt
    40021 tataatcctt tcgttttaaa atactatctc agatattctt atatcgacaa gaagtttttg
    40081 agtcattccc tcatcataca tattaaataa atagtggctc attcaatttt tcactagaat
    40141 aataagctag tatagtaaac tgaaataaga tataaacaaa taaattggag cttaacatcc
    40201 atttccagca attttttaga aactacagtg gactattcta gattcaacat attataaaaa
    40261 ctagagtaaa agaaaaggat tggatcttgt gtaatgcagg atccaatcct ttcaatcatt
    40321 ttgtccaact tttggaggtt cctacaatgt agccgtcatt aataaagaca gatgggaacg
    40381 acagtgttcc tatttatttt gatagagatc gatgaattct ttagatagca actgaataat
    40441 ctccgttgaa gccatttggt cttctgcatg cataaatagc aaggagaatc ctattttttc
    40501 tccagtagct tctttttgta tgagattaga gtgaatcttg tgcacttcta ctaaggagtc
    40561 ttccgcttct tcaactttaa ttttcgcttc ttttaaattt cctgccttag ctagttggat
    40621 ggcttcaata aaggatgatt tggctgctcc actattggca atgagctgaa aacagatata
    40681 ttccatttct tctgtcatct tatttctcct atccatgcaa gtgcttgttc cagaactttt
    40741 gctccattca tcattccgta atcccgcata tcaatggtat ctacagggat atttcctgca
    40801 atttctttca cagcaagtaa ctcataacga atttgtggcc caattagaat gacatctgct
    40861 tcatggatat tctttttcgc ctctgtcatt gattttgctt ggatagaaat ttcaatccca
    40921 cgttcagtcg cactttgttg cattttttta acaagcatac ttgtcgacat tcccgcatta
    40981 catactaata aaatttgttt cataatctta accttccatt tcttgttcaa caactttgtc
    41041 attaactttg ataaatggaa tgtatagaag aactccaagt gcaaagatga tgaattgaac
    41101 tagaactgct ctcacgtccc ctgctgttgc taaccatgca tttaagaata ctggtgtagt
    41161 ccaaggaact tgtataaatg caggactcat gaatcctgta actgttgcta agtagctgat
    41221 taaaatacca aggactggaa ctgtgataaa tggaatagct aatgaaatgt tataaacgat
    41281 tgggtaaccg aataatactg gttcattgat attgaagata ccaggtccaa aagataattt
    41341 agccacgttt ttagagacag cattgcgact cactaagaat gttgctatta ataaacataa
    41401 tgtagatcca ctaccaccca ttaaagcgaa tgtttgtatt tgtgataggt tgatgatgtg
    41461 tggaatggct tgtccattat ttgctgcagt gatgttttca gtaatgttaa ttaatagtaa
    41521 tggttctagg atggcactgt aaataactgc ttggtgaata ccaaatagcc ataacatatt
    41581 tcctaaagag taaataataa tgaccccgat taagcttgta ccaatatgac gaattggttc
    41641 ttgaataaag attgtaatga ttgagattaa gttcattcca gttatattga ataataatgc
    41701 tgaaacaacc ccaaataagg agatgacggt catgactgga agtaatacgc taaatgatct
    41761 actaacagct ggtggaatat tttcaccaag gttcatttgt aaagctttaa cgtttgataa
    41821 ttcaatgaat aattctgttg caataatcgc tacgataacc ccggcgaaca ttgcgcctgt
    41881 acctgtgttg ttgaatgaaa gaacacctga aatgtttacc gcatcttttg ctccgtcagg
    41941 aactacagaa actgtatttg gcatcatcac aattaaagaa actaatgata gcattgatgc
    42001 tgctaacggg ttttcgaaat ctctgttttt agctaagaaa taaccaacca ttacagcaat
    42061 aatcatacct gaaatactta aagtaccgtt tgcaattgtt attccccaat attggaatct
    42121 tgttaatgta tccccttgga aaatccactt aaataccgtg ttgttcaaaa gaacgattaa
    42181 acctgccaaa atatataatg gcattactgt tacgaatgca tctcttaggg tttttaaatg
    42241 aatttggttc cctagtttac cagcaaaggt ggcaaattgg tctataaatt ttgagttttt
    42301 catatgaata tctcctctct ttactcctca atttctactt caaaaccgtt attgtcactt
    42361 actttgcgat accatcttcc tgagctcttg atggttctct tttgcgtttc taaatcaacg
    42421 gagataaatc cgtaacgatt cttatatgca ttattccaag accagcaatc aaatgcggtc
    42481 caagcgtggt atccaaaaca gtgacttccc tcttcaatgg ctttatgtag ccatcttaaa
    42541 tgttcttcat aaaattcaat acgatacacg tcatcgataa ctccattttc atcgataaac
    42601 cgtgcttcgt tttcaacacc cattccgttt tcactgataa accatgggat attaccatat
    42661 tcttccttca caatcatagc aatatcataa atggctttcg gaaaaatttc ccaaccacga
    42721 tatggattca tgcgacgctc cagccattca tactctttga agtattggtc tggcatccag
    42781 ggcgtctgat attcttcagg atttgcttgt gcttgaacac gttttggatg gtagtagttt
    42841 actccaagaa aatcaaccgt atttgatttc atcagttgaa gctctttttc ggtatgactc
    42901 cataacacgc catctctctc tagctgtttt accaatcttt ctgggaaagt tcctttaaca
    42961 gctggattca agaagacttt gttaaagaag tcatctgtaa atcgacttgc ttctaagtct
    43021 tctggagaat tacttcttgg ataagcaggt gtcaagttta aaataatccc aatctttcca
    43081 tcaagttcta atgagcgata tagttgaatc acttttgcac tagcaaggtt tagattatag
    43141 atgacttgta cggcctcttt tccctttcct tttagatttg gataatggaa agcatataag
    43201 tatcctgctt ctggaatgac cattggctca ttgaaagttg tccagtaatg aaccttatct
    43261 ccaaagcatg tgaaagcagt cttggcaaac ttcacgaata actccactac atgtttgctt
    43321 tcccaaccac cgtatttttg aagaagttcc actggtaaat caaaatgatg taaattcatc
    43381 acaagatcca tctggttctt tttagcttct tcaatgatgg cattgtagaa agcaatacct
    43441 tttggatcag gctcacctgt ctctaaattc ttgatgagtc gactccattg gatggaagtg
    43501 cggaaagaat taactccaat ttccttcatc aagtggaaat cttcggtgta agtatgaaaa
    43561 aagttactgg ctacaagagg tccgacatta tcgaaaaaat cttctggatg cgttttgaac
    43621 cagtagtcca tcacattttc atgtactttt ccatattgac cttctgtctg aggtccgcta
    43681 gaagcagctc cccaccaaaa tagattagga aatactaact tttttttcat gctcaacctc
    43741 ctttctatta ttctatacat aaagtatagc ataattttaa aatttgtcta gacattttta
    43801 aaaattgttg atacatatct tgtgtttgcc tcatttcttg aactttgtta tactactatt
    43861 agaatattat agagagaacc agattaaatg agtacaaaat atttatttat ttacaatgag
    43921 attcgtgaaa agattctttg taataaatat accatgaacg aacaattgcc tgatgaaatg
    43981 acattagcta aacagtttgc ctgtagtcga atgacgatca aaaaagcttt agacttgtta
    44041 gtttctgagg gcttaatttt tagaaaacgt gggcagggaa cctttgttct ctctcgtggc
    44101 agctcaaaaa gaaaattaat cgttccagaa agagatatcc ggggactgac aaaaatatct
    44161 gaagatgctc attctacaat tgactcgagg attattcact tcaaattaga atttgcaaat
    44221 gaatttttag cagaaaaact acaggtcgct ttgcagagtc cagtttataa tatttaccgt
    44281 ctgcgtatta ttgacggtaa accttatgtt ctggaacaaa cttatatgag tactgatgtt
    44341 attccaggta ttactgaaga tattttacaa aaatcgattt acaattacat tgaaggaaag
    44401 ttaggattgc atattgccag tgctacaaaa atcttgcgag cttcttctag ttcagaaaat
    44461 gagcaacatt acttgcagct ccttccaacg gaaccggtat ttgaagtaga acaagtggct
    44521 tatttggata acggaactcc gtttgagtac tcgattagtc gtcatcgcta tgatttattt
    44581 gaatttaatt cttttgcatt acgacattcc tcctaggaga aaatgtgaaa atgaagccaa
    44641 tcttttacag actctagttt aagaaaaatt taaaacaggg caagaaggtc ccatctatgc
    44701 ttaaatggtt tctcttttct aaataagatg gctttaaaag agtgatcgtt ttatccatca
    44761 tgttgaaaaa tatcttcgta tagcttatag agtaggtact gaaattgttc acctgatcta
    44821 cttcttatag ttatttagtt ttaaatagtg tttcaaatat tcttacactg acgagaagtt
    44881 tttgagtctt ttcttgtaac acatatagta tactgatgtt agaatagtag actgtgactt
    44941 ctaacaaatt gctagaaatg aatttcaatc tcccaattta tttgttcata tcttctttta
    45001 atatattaaa taaattctga atcataatca tttaaaaaaa ttttattttt tatttttcat
    45061 tacgaataat atagatgaag gggaaagagt atgaaaacag aacggtttct tttgctatta
    45121 gttcaaaagg agaaaaaatg aaagtagaaa atatttcgta tagggtggat catcgtatat
    45181 tgtttgataa tatttctttt gatacttcga gttcaggcgt gacattaatt actggtaaaa
    45241 atggtacagg aaagtcaact ttactatagt agattgaaac tagaatagta cacatctact
    45301 tctaaaatat tgttagaaat cgatttgact atcctgatct atttgtcctg ttcttatttc
    45361 atttcactac atctcaaatt gagtatgacg aagtgcgctc ccatgtcctg ggaacgcact
    45421 ttcttcatat ttttcatatt cttgaatcca tcgataaaga ctattgggat gaatttttaa
    45481 agttgaacta attattttta caggatgagg tttacagcag agagtttgaa ggctttatca
    45541 aaggtttttc ttggcataat gacttttcct cgtttccact taattttgtg tctactttat
    45601 tataccaagt ccacccttaa gttagataat gaatctaact taaggaagct agaaggatga
    45661 gaatccaggt ggtcaagagt cccaaactta agctgatagg gacacccaga ataatttgct
    45721 ttttgaaggc aagaccgcgt tcctctatat tgggaagtga gagttgaatg agagaaccag
    45781 ctgatgaaaa gggtgagata ttagtagata gagcgccaat aacggtggct gttgtgagta
    45841 agtgaatatc aatctgagga ttttgagcac tgatgatagc aatgatggga aagagggctg
    45901 gagctacaac ggatagggtg gaactaaaga gtgacatcac tccggctatc acacaaaaga
    45961 acagaggtaa ccagaaatga ggaatggttg ttgtcatgag gtgccctatc agtgtgacta
    46021 aacctgactt gaccgctaga gacattagta agctcatgcc gcagagcatg ataattgtag
    46081 cccagggaac cttagctaaa atggcttctt gcttccctaa tttgagcttt aaggcgaggc
    46141 agaccatgag tattgagaca aagccaatat caaatgtttt ttgataagta gctatccagg
    46201 cgatgtttgg gaaaatgaga tgcaacaagg gaaaaagcca aaccaaaacc atgctgctga
    46261 tcatgagcaa ggtggtttgt ctttgaacct tgctgaggag tggtggttgg tcaatagtca
    46321 aggatgagtt tgttcttccc ttactatagt gactgtaaca ggataataaa agcaagacga
    46381 tgagtgggta gataatgctg acgataaaga tatgattgcc aagtgaaaaa gcttgctctt
    46441 cccatcccat ttgcttaaac aggccttgaa agacaatgcc tgagctactg gttatcaaat
    46501 tagcccctcc tgaagctccc caattgacgg cttgagctcc aatcaaaggg tgtttgtccg
    46561 ctttttgaca gagggtaatc gctagaggac agcaaacggc catagtagtg aaaaatccag
    46621 cacctaaagc agacaaaagg gttgccatca ggtataaaat catgtagagg gcgttagggt
    46681 gggtgcgtgt gcggtagaga atgtgttgag ccaaaacatc aagagtaccg ttagttgttg
    46741 caacgttata aaagagagag acgctaaaaa tggtaaaaaa gagtgaggtt ggccaaaaat
    46801 gaagaagttc tttggggctt aatcccatga gagtggttgc gatgaggtaa gaaaaagcaa
    46861 tagccagcag gccaatattg attttggtgc ggtaaccaat tccaatggct agagcaatgg
    46921 cgctaatcat tattaaatga atcattgaat tgtcctttca gttagaatat ggaaataggt
    46981 tggcaatttt ggcgctcaaa agaccacctg tttcctattg gtacttgact attatacaca
    47041 aaaaaaatac aattgtcttg acaattgtat tgacacttgt tagaattaaa aatgaggtat
    47101 tcaggcttgt gatttcctat ggaagttaat agtaattgcc tctagtgctt acaagtgata
    47161 ttaaaaatag aggacttagt gatgtcaatc atttcaactg atttaacccc ttttcaaata
    47221 gatgatacat tgaaagcagc cttgcgagaa gatgttcatt ccgaagatta cagtaccaat
    47281 gccatttttg atcatcatgg ccaagctaag gtgtcgcttt ttgccaagga agctggtgtt
    47341 ttagcggggc taaccgtttt tcaaagggtt tttaccctat ttgatgccga ggtgaccttc
    47401 cagaatcctc atcaatttaa ggatggggat cgtttgacta gtggcgattt ggttttagaa
    47461 atcataggct cggtgagaag tctcttaaca tgtgaacgcg ttgccttgaa ttttttacaa
    47521 catttatcag ggattgcttc gatgacagct gcttatgtag aagccttagg cgatgattgc
    47581 attaaggtat ttgatactcg aaaaactact cctaatttac gtctttttga gaaatatgcc
    47641 gtgagagttg gcggtggcta taatcatcgc tttaatttat cagatgctat catgctaaaa
    47701 gacaatcaca ttgcggcagt aggtagtgtt caaaaggcaa ttgctcaagc gcgtgcctat
    47761 gccccttttg tgaaaatggt cgaggtggaa gtggaaagcc ttgctgctgc cgaagaagct
    47821 gcggcggcgg gtgctgatat tatcatgttg gataatatgt cattggaaca gattgaacag
    47881 gccattaccc taattgcagg acgttctcgg attgaatgtt ctggaaatat tgatatgacc
    47941 actattagcc gttttcgtgg tttagcgatt gattacgtct ccagtggtag tttaacccat
    48001 agtgctaaga gtcttgattt ttccatgaag gggttaacct accttgatgt ctaagttgta
    48061 aaataaacta actttttaaa ggatgtcttt cctctagaac gagttttatg tcagatagtt
    48121 taaacgcctc ttcaa
//
LOCUS       DAYYYC010000011        46866 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.011, whole genome shotgun sequence.
ACCESSION   DAYYYC010000011 DAYYYC010000000
VERSION     DAYYYC010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46866
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.011"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(4..300)
                     /locus_tag="ACHBV5_000616"
     CDS             complement(4..300)
                     /locus_tag="ACHBV5_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966460.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(284..2443)
                     /gene="pfbA"
                     /locus_tag="ACHBV5_000617"
     CDS             complement(284..2443)
                     /gene="pfbA"
                     /locus_tag="ACHBV5_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HFM9966461.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYSGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVVN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKINNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3573..4799)
                     /locus_tag="ACHBV5_000618"
     CDS             complement(3573..4799)
                     /locus_tag="ACHBV5_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HFM9966462.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFKNEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4842..5534)
                     /locus_tag="ACHBV5_000619"
     CDS             complement(4842..5534)
                     /locus_tag="ACHBV5_000619"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFM9966463.1"
                     /translation="MLKWEDLPVEMKSSEVESYYHLVSKRKGSLIFKRCLDWFLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5707..7458)
                     /locus_tag="ACHBV5_000620"
     CDS             complement(5707..7458)
                     /locus_tag="ACHBV5_000620"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966464.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDDQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMADTL"
     gene            complement(7448..9193)
                     /locus_tag="ACHBV5_000621"
     CDS             complement(7448..9193)
                     /locus_tag="ACHBV5_000621"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966465.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9321..9851)
                     /locus_tag="ACHBV5_000622"
     CDS             complement(9321..9851)
                     /locus_tag="ACHBV5_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFM9966466.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            complement(9848..10304)
                     /locus_tag="ACHBV5_000623"
                     /pseudo
     CDS             complement(9848..10304)
                     /locus_tag="ACHBV5_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10438..11265
                     /locus_tag="ACHBV5_000624"
     CDS             10438..11265
                     /locus_tag="ACHBV5_000624"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFM9966467.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11277..11372
                     /locus_tag="ACHBV5_000625"
                     /pseudo
     CDS             11277..11372
                     /locus_tag="ACHBV5_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
     gene            11420..11659
                     /locus_tag="ACHBV5_000626"
     CDS             11420..11659
                     /locus_tag="ACHBV5_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HFM9966468.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12042..12137
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12537..13118
                     /locus_tag="ACHBV5_000627"
     CDS             12537..13118
                     /locus_tag="ACHBV5_000627"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFM9966469.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13118..14380
                     /locus_tag="ACHBV5_000628"
     CDS             13118..14380
                     /locus_tag="ACHBV5_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFM9966470.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14430..14891)
                     /locus_tag="ACHBV5_000629"
     CDS             complement(14430..14891)
                     /locus_tag="ACHBV5_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HFM9966471.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(14888..15652)
                     /locus_tag="ACHBV5_000630"
     CDS             complement(14888..15652)
                     /locus_tag="ACHBV5_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnI domain-containing protein"
                     /protein_id="HFM9966472.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYYPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(15833..16237)
                     /locus_tag="ACHBV5_000631"
     CDS             complement(15833..16237)
                     /locus_tag="ACHBV5_000631"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HFM9966473.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVIGQRSEERRVRI"
     gene            complement(16307..17788)
                     /locus_tag="ACHBV5_000632"
     CDS             complement(16307..17788)
                     /locus_tag="ACHBV5_000632"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFM9966474.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWETYVHYPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIVAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVDQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKAFRFAGFEQVKAGIVKWPMSVLRLTSDSKEDLINLADKILQEWRQYSDPAVQ
                     ILAETDRTPHHTITPIARKRDGQFELDLVLRDNQTSAEYPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(17807..18985)
                     /locus_tag="ACHBV5_000633"
     CDS             complement(17807..18985)
                     /locus_tag="ACHBV5_000633"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFM9966475.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKETVGKHYEEVVGYAPSFYIAEVAGGTHVLD
                     "
     gene            19150..20157
                     /gene="galR"
                     /locus_tag="ACHBV5_000634"
     CDS             19150..20157
                     /gene="galR"
                     /locus_tag="ACHBV5_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HFM9966476.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(20203..21240)
                     /locus_tag="ACHBV5_000635"
     CDS             complement(20203..21240)
                     /locus_tag="ACHBV5_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HFM9966477.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21241..21594)
                     /gene="nmlR"
                     /locus_tag="ACHBV5_000636"
     CDS             complement(21241..21594)
                     /gene="nmlR"
                     /locus_tag="ACHBV5_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HFM9966478.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(21838..22728)
                     /gene="czcD"
                     /locus_tag="ACHBV5_000637"
     CDS             complement(21838..22728)
                     /gene="czcD"
                     /locus_tag="ACHBV5_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HFM9966479.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            22861..23397
                     /gene="sczA"
                     /locus_tag="ACHBV5_000638"
     CDS             22861..23397
                     /gene="sczA"
                     /locus_tag="ACHBV5_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator SczA"
                     /protein_id="HFM9966480.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFQKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FIGQEVVQFYLDLLIPKN"
     gene            complement(23563..24369)
                     /gene="pnuC"
                     /locus_tag="ACHBV5_000639"
     CDS             complement(23563..24369)
                     /gene="pnuC"
                     /locus_tag="ACHBV5_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFM9966481.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(24714..26234)
                     /locus_tag="ACHBV5_000640"
     CDS             complement(24714..26234)
                     /locus_tag="ACHBV5_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFM9966482.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDSIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(26227..26955)
                     /locus_tag="ACHBV5_000641"
     CDS             complement(26227..26955)
                     /locus_tag="ACHBV5_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFM9966483.1"
                     /translation="MIEYKNVALCYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(26969..27733)
                     /locus_tag="ACHBV5_000642"
     CDS             complement(26969..27733)
                     /locus_tag="ACHBV5_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HFM9966484.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGATYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLKNGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(27737..28180)
                     /locus_tag="ACHBV5_000643"
     CDS             complement(27737..28180)
                     /locus_tag="ACHBV5_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFM9966485.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(28862..29158)
                     /locus_tag="ACHBV5_000644"
     CDS             complement(28862..29158)
                     /locus_tag="ACHBV5_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFM9966486.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(29180..30244)
                     /gene="pepA"
                     /locus_tag="ACHBV5_000645"
     CDS             complement(29180..30244)
                     /gene="pepA"
                     /locus_tag="ACHBV5_000645"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFM9966487.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALLGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            30645..31346
                     /gene="galE"
                     /locus_tag="ACHBV5_000646"
     CDS             30645..31346
                     /gene="galE"
                     /locus_tag="ACHBV5_000646"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFM9966488.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMDQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            31362..31472
                     /locus_tag="ACHBV5_000647"
     CDS             31362..31472
                     /locus_tag="ACHBV5_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HFM9966489.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            31769..32728
                     /locus_tag="ACHBV5_000648"
     CDS             31769..32728
                     /locus_tag="ACHBV5_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9966490.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFISSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            32718..33674
                     /locus_tag="ACHBV5_000649"
     CDS             32718..33674
                     /locus_tag="ACHBV5_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFM9966491.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            33671..34423
                     /locus_tag="ACHBV5_000650"
     CDS             33671..34423
                     /locus_tag="ACHBV5_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966492.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            34519..35484
                     /locus_tag="ACHBV5_000651"
     CDS             34519..35484
                     /locus_tag="ACHBV5_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM9966493.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETSTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(35709..35951)
                     /gene="yidD"
                     /locus_tag="ACHBV5_000652"
     CDS             complement(35709..35951)
                     /gene="yidD"
                     /locus_tag="ACHBV5_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFM9966494.1"
                     /translation="MKRILIALVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(35951..36673)
                     /locus_tag="ACHBV5_000653"
     CDS             complement(35951..36673)
                     /locus_tag="ACHBV5_000653"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFM9966495.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(36660..37229)
                     /gene="scpB"
                     /locus_tag="ACHBV5_000654"
     CDS             complement(36660..37229)
                     /gene="scpB"
                     /locus_tag="ACHBV5_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFM9966496.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQALDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(37248..37976)
                     /locus_tag="ACHBV5_000655"
     CDS             complement(37248..37976)
                     /locus_tag="ACHBV5_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFM9966497.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(37976..38710)
                     /gene="xerD"
                     /locus_tag="ACHBV5_000656"
     CDS             complement(37976..38710)
                     /gene="xerD"
                     /locus_tag="ACHBV5_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFM9966498.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVTIP
                     TALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(38707..39168)
                     /gene="cbpB"
                     /locus_tag="ACHBV5_000657"
     CDS             complement(38707..39168)
                     /gene="cbpB"
                     /locus_tag="ACHBV5_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFM9966499.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(39165..39686)
                     /locus_tag="ACHBV5_000658"
     CDS             complement(39165..39686)
                     /locus_tag="ACHBV5_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFM9966500.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(39662..40633)
                     /locus_tag="ACHBV5_000659"
     CDS             complement(39662..40633)
                     /locus_tag="ACHBV5_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HFM9966501.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(40630..41424)
                     /gene="racE"
                     /locus_tag="ACHBV5_000660"
     CDS             complement(40630..41424)
                     /gene="racE"
                     /locus_tag="ACHBV5_000660"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFM9966502.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(41631..41879)
                     /locus_tag="ACHBV5_000661"
     CDS             complement(41631..41879)
                     /locus_tag="ACHBV5_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFM9966503.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42135..43760)
                     /gene="treC"
                     /locus_tag="ACHBV5_000662"
     CDS             complement(42135..43760)
                     /gene="treC"
                     /locus_tag="ACHBV5_000662"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFM9966504.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(43938..45905)
                     /gene="treP"
                     /locus_tag="ACHBV5_000663"
     CDS             complement(43938..45905)
                     /gene="treP"
                     /locus_tag="ACHBV5_000663"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFM9966505.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFVYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            46090..46800
                     /gene="treR"
                     /locus_tag="ACHBV5_000664"
     CDS             46090..46800
                     /gene="treR"
                     /locus_tag="ACHBV5_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFM9966506.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
BASE COUNT        13699 a        10654 c         8788 g        13725 t
ORIGIN      
        1 ttattatttc attttactat actctgttaa ttcatatgag tttaaaccga tttcatcttt
       61 aacctcgagt aaagcagttt caaatatttg tttaagagtt tttgattctt tacaattaac
      121 cgacaaactt tctgataaaa tatgtacaac ttctgagact gaataaccta tctcctcttt
      181 agaattatat aaatctgtag ctccaccaat aatccaaaaa tactgatttt gtgaacctac
      241 aatatcctca ttttctacgg aacttccttg tatcgaacaa attttattta tctttaccat
      301 aatacttcaa cccttttagt gtcaaaagta aaccaattcc tgtcactgtt aagaatagtt
      361 ccataatctt gttcgaacca gtctttggta atttttgttt tacatctact atttctttag
      421 atttattaat atgattttca gtttctctgc catctccaac tattttatag tttacttctt
      481 ctgtcttatt atcttgttta ttgttgatct tgtcattcat ttgtctatta tctttacttg
      541 agttaaactc tccgttcttc tggttactat caattacatt atttgaatta gattgttttt
      601 cctctttgtt tttttctttt tcgtttttat cacttaaatt atttgttaca attttgtaaa
      661 gcccattctc cgttacaata ttgaaattac catcgctatc acgtataaca ggttctttcc
      721 catttgcatt agatttgatg aatgatatat acttaccgga taaattataa aattggttat
      781 ttaaaacggt tattttaccc tttgaatcct caataacaat tccttcttta ccaccgaata
      841 tactattctc tgagactact aaattatcac taactcgtaa taattcaata tttggttgtt
      901 ctgtttcctt agaattatta ttaactacat tttttgttac agtaatatct gatacttttc
      961 ctaaatattc tgcactatct tttgcaactc gtatcgcttt tgttttagga tcggcaatat
     1021 taaatatatt ttcggcgata accacctgtt tatttaaatc taataggtct ttagtgtttt
     1081 tatagctata agcatttact aaagctgctc cgctttctcg ataatgtaca ctctctcctt
     1141 taactttctt atcaaagcga tttcctttga ttaatacatc agtgaatcct gtaaaacgta
     1201 cacctgaata catcatgtta tcaaaatgat tatttaaaat tttaatatta gaggggttct
     1261 gtgtcgacaa tgtttgatag tgtgtgccaa ttgctgttac taattcccca gatttatcac
     1321 ttttgccaaa ataggaattt tgaatagtca cattttcaga ttttttccca tcatcattca
     1381 aggcataagg aaaacctttt ctagttaatg gttcaatctg aatgctctcc ttacttatga
     1441 tttgcccatc cttcatcgtt ttgggtaagg cttgcccaag aaaacgagaa ttatcaacta
     1501 atacattttt cgaacctgca atttgaatag catgcccttg ataactatcc ttgaatgtta
     1561 cattttttat agttacgtta tttgaattcc caatagcaaa tgcacctgaa gaatttataa
     1621 gtggtagatt ttttgcttta gttccttctt cattcaaagc accgttcata tcaatcgtac
     1681 caccagaata actaatatct tctgttgggc cccattctac ttgcgcacca tcatccgtaa
     1741 ataaacctgt cataaaaaca atggaagggt gattcttaat atttatacca tttagaattg
     1801 tagctttctc attcaattct aagtgtgtat gactttttaa aaaaacaatt tcttttacta
     1861 aataagttcc ttcaggaaaa tatacatttc ctccacctag cccttgagct gcagcatcta
     1921 ttgcatcttg aattgcttgt cgatcatcat gaatcccatc acctaccgca ccataatctt
     1981 ttacacttaa agcagtatct tcaaattctt ttttgataat tctgtcactt ataacatctt
     2041 ccttataact cttattttca ttagtagatg ttactgtaga ttcaactgtt ctgttgtcta
     2101 attgtgaatt ggaacgaata gtaccattag agctgatact attaacactt aacgaattat
     2161 ctaaaccatt agtggttgaa ttagaggcaa tcatttcagc agaacgattc tgattaacag
     2221 ttggtgaatt atctaaatca ttagtaattg cattagaaga ctcttttgta gccatcggtg
     2281 aagaactagt aacaacttca tccgataaaa taccttggct tcccaaaatt gaaattgcca
     2341 atagtaccga gcaagtccct acctttaatt tacgaatact gaatacctca ttaggaacaa
     2401 aatatttcat cagaacctcc aattttttta ctatttttaa caattgatta ttacttttct
     2461 taaaatagat agaatgacac cgctgtcatt atctttatca tatattttcc aaattgaatt
     2521 gtcaaggaat aacacaagaa aatattaaaa tttatactct tcggaaatct cttcaaacta
     2581 ggtcagtgcc gccttgccct aagtctaggt tactgacttg gtcagttcta tagtagacgg
     2641 aaactataat agtacacctc tacttctaaa acattgttag aaatcgattt gactgtcccg
     2701 atcgatttgt cctattctta tttcatttta ctatatctac aacctcaaag cagggttttg
     2761 agctatctat ggccaacttc ctagtttgct ctttagcctt ccattcaaaa gtgatgctat
     2821 ctttcttagc ttgaatataa aatatcccat ttactatatt taaatttgtt gatatgttgt
     2881 aaattataaa tgaaagaaca aataccttgt catacaagca ttcgccaggg atatttacat
     2941 gaatatcgct catatggcgg attgaaacta aaacactaca atatatttct taaatagacc
     3001 ttctataaaa gctagattta acctcgataa aaatagatgc agtgcttcta aaatactgga
     3061 atagggcata taggtaatcg tagacaagtg ttttatagat tgtctcgcgg gagatctaat
     3121 gatgtatagc aagcatcact aaacatatag aatatttgta ttattataag atcaatatgc
     3181 tataaattct atcatgcaaa agaatgacta gaacatgaaa gacaggcaca aaactttgaa
     3241 caatattctg aaaacaaaaa aagacgcgag tttccacaat ctcactcatg gaaactcacg
     3301 tctttcaaaa aatagggtga attgaaaact agaacaagac actagatttt ctaaatgatg
     3361 tctagtaagg attctaaatg ctacaccaaa ttgctcacat cttatttcaa accacgggac
     3421 tctcacaaga aaggaaaatc ctataaaaat tctctctctg aggagaaaga ggcctcaact
     3481 acaggtgtaa actattatca attgaaaaca acagttttta cactcaatta gactttttag
     3541 ggacaggatc actttcgctt gactgtagtt tgtcattttt ttgataaagt tagcactttt
     3601 tcagaaactg ttttgaaagt ctcaatgata tagtctactt cttcatcgct taatttagta
     3661 tgaagaggga gggtaatttc attcttaaag aaggcatagg ccttaggata gttcgtcata
     3721 tcaaatccaa gattcttata ggctgtcaag agaggaagcg gtttgtagtg aacattactt
     3781 gcaattcctg ctttagccaa ttcttggatg atgaggttgc gttcttctag gcttgctcct
     3841 tctacacggg tgatgtagag gtggcgtgaa gattcgacag tttcagtctt gtgtgccaaa
     3901 ggatggatgc gagaacctgc aaaaccacta tcatagcggt ccacaatgtc cttacggcgt
     3961 tgcaacaaac ttggatagcg gtccaattgt accaaaccaa gtgaagccat gatatcggtc
     4021 atgttgcact tataggctgg tgtaacgata tcgtattccc atgaccccag ttgcatcttg
     4081 gcaagagcat ccttagtttg cccgtgaagg gaaaggattt ggaattcctt gtacatctct
     4141 tcgtcatcaa tcactggatt ggctttccaa gtcgcacttc caccttctgc cgttgtaaag
     4201 ttcttaacgg catggaatga gaaggaagta aagtcagcga tagaaccaga aggttgtcct
     4261 ttataagtag atcccaaagc gtgggcacta tcagagacaa tgacaatacg gttaaaggcc
     4321 ttttgccact tgcttgaagc agtaaagaag tcacgttttt tctccacgac ttggaacaaa
     4381 cggtcataat cgcaaacaat ccctgcgagc tctactggga taatcacctt agttttctca
     4441 gtgatagctt gctcaagcag gtcatagtcc atctcaaacg tatctgcttg gatatccacc
     4501 atgacagggg ttgctcccac gtgcgtaatg acactacatg aagctgtata ggtcatggct
     4561 ggaacgatga cttcatcacc aggtcccact tccaaaacgc gtaaaatcaa ctccagagcg
     4621 gctgtcgcag agttgagaca aacagtctta ggtgtctgtg tgtaaagaga caagcggcgc
     4681 tccagttctt ttgttttagg acctgttgtg atccaaccag aacgcagggt atccgctact
     4741 tcagcaattt ctgcttctgt gatatcaggc ggtgaaaatg gaatattgta atttggcatt
     4801 gatttgctcc ttttatctgt actcattttc ttatgactac tttattttag tacctcaaac
     4861 acggtttgaa acatgatttt gatgtcccca aagaaactaa actctcggag ataggcgagg
     4921 ttatagcgca tcttttcagg aagaacatgc tccacatagg cctgatcaac tgacagacct
     4981 ttctccgtca tttgactgat gatggtgtcc tcatccttgt agttgatgct ggctggagag
     5041 gtaattcctg cttgcaagag caaggttgcc atcatttcag ggctatactg ctctgtataa
     5101 cgtggcactt caggtcgtgt accgacaaag gacatctcac ctttaaggac attgaccaac
     5161 tgaggcagtt cgtccaaacg gacacgtcgg atgaaatttc caaccttggt aatacggcta
     5221 tcgttagcag aagtcaccag acttcctttt ttatccgcat ccgtcaccat ggtacggaac
     5281 ttccaaatct tgaaccgacg gttgtactgg gtcacacgct cttgcttgta aatcactggc
     5341 cccttgctat ccaacttgat ccaaatgctc aagatgagaa agatgggaga ggttagaacc
     5401 agtaagacca aggccaaaaa ccagtccaag caacgcttga aaatcagcga acccttcctt
     5461 ttagagacaa gatggtagta agactcaacc tcgcttgatt tcatttccac aggcaagtct
     5521 tcccatttca gcatactgtt ctcctttgtt tttattatac tatttgtcaa catttttcat
     5581 tataccacaa aatggaaaag gcggtgaaag aaatctgtaa tttgaaggat ttccttctag
     5641 tactcaatga aaatcaaagt acagctttga gattgcagat aaagctgaca tggtttaaag
     5701 agattttcaa agagtatcgg ccatggcccc tgcctgcaaa ctatacatct tgtgataggt
     5761 tcctcccaga gtcaagagtt cctcatgggt tccactctcg ataatgcgtc ccttatccaa
     5821 gacatagatg cagttggcgt cttgaatagt agaaaggcgg tgagcgatag caatagttgt
     5881 tcggccctgt ctcatcttcg ccagagaagc ttgaaccaag ctttctgttt cagagtcaat
     5941 attggctgtc gcttcatcca aaatcaggat tttaggctgg ctggcgactg ttctagcaaa
     6001 ggcaagaagc tggcgctgcc cagtagagaa gctcgaacca cgctcggaaa caggggagtc
     6061 gtacccctga ggaagttctt gaataaagga atctgcatcc acaaaggctg ccgcagcctg
     6121 aacctgatca tcactgattt cttggtacat ggcgatattg gacttaatag ttccatgata
     6181 gaggaagggt tcctgcaaga ccaaaccgat gttttttctc agctcttctt gactgaaatc
     6241 cctgatatcc acatcatcca agagaactct ccctgactgg aattcataaa agcgcatgag
     6301 gacattgata atagacgatt tccctgaacc tgtatgacct acaaaggcaa tggtttcacc
     6361 cttattaaca gagaaagaaa tgtcatccag aatcggatgt ttaccgtcat atgagaaaca
     6421 cacatgttca aaacggatat tgccttcttg gactttggct tgcccatttt cttgaagagg
     6481 ttcataggtc ctctcgtcta tcagggcaaa gacacgacct gcagaaacca tagccgtttg
     6541 cagagttgaa aagttttgcg tcacctcaat caaggggtca aaaaggcggt tgatgtactg
     6601 gataaaggca tacatggtcc cgaccgttat cccgatagaa aaaccacggt agccaaagta
     6661 ggccatcaag actgcatagc ctagaagttt cagcaaactc atggcaggtc tcaaaaagag
     6721 ggcatccaag gctacagaac ggttggcgta gaccaagtgt tcttggttga tttcatcaaa
     6781 ttctgcctgc aggcgcttct cttgattaaa agcctgaata atcctgattc cctcgatatt
     6841 ctctgccagc ttactattga tatctgacaa gagacttctg gttttctcaa tgattttcac
     6901 tgattttttc cgatagagat tgaccaaaag gaaaatcaag gggagaaaga gcaagactaa
     6961 tgctgtcaaa cgaaaatcca ataccaacat ggtataaagg gttgtcagaa agatgaaaac
     7021 tgctgagata aagctggata aaatccccga aaacatatca ctgatagtct cggtgtcatt
     7081 tgtcaaacga gagacgatag agcctgctgg cgtcttgtca aagtaagaca tgcccagttt
     7141 ctccatattg gcaaaggcat cccgacgaat atccctaaca atactgtaag acacgcgcgc
     7201 aaagagaaga ttgcctacat actgaactac agtttgtagg atgtagagac catagtagac
     7261 cagcaaaacg gtaacggcta gttggttaag attgctgaga tactggtcga taaagtggga
     7321 agccacgagg ggtatgacac ttttaatgac cgtcgtcgct aggagaaaac tgagtgccaa
     7381 aaaggtcagg agtctataag gcttgagata agacatcaag cgcttcaata cagcccattg
     7441 ttcttgttta ttctgcatct tcttctcctt tcatttctaa ctgctgagac tggtaggttt
     7501 gggcatacca gccatccatc gctagcaagt cttcgtgcgt gcctcgttcg ataatttgac
     7561 cattttgtag aactaaaata aaatctgcat ggacaacagc actgaggcga tgggcagtga
     7621 taatggttgt cttgtccttt cgcgtctcct tgaggttgtc gataatcgca tactctgtct
     7681 tggcatctac ggcggataag gaatcatcca aaatcaagat atcagggtct aaaatcatag
     7741 cccgactcat agccaaccgt tgcttttgac caccagaaag actgactcct ttttcaccaa
     7801 tcagcgtatc aaatccttga ggcatgtcta caatatcttg gtaaactcgg gctagcttag
     7861 tagcttcctc gaccgctgaa aggggcaagt taggattgcc aaagcggata ttgtctagga
     7921 ttgaagttgc aaagagaaac tggtcctgag gaacatagcc catgagactg cgaaggtctg
     7981 tcagacgata gtcccgaata tcgtgaccgt ttagataaat ggcaccctta tccacatcgt
     8041 attcacgcaa gaggagcttg attaaggacg ttttcccaga gcctgtctgc ccaaccaagc
     8101 ccagtgtttg cccttttgcc aaactaaagt gaatatccgt cagtgtttcc tcattttcaa
     8161 aagcaaagct gtcaatggca tactccaaac gcccattttc aataccatcc agaggaaact
     8221 cagggtcttg tacaggagat tcctgagaca aaagattttc aatccgctgg taagaaacct
     8281 tccctcgctg agtagtatta aagaggaagc cgatggccat aagaggccag accagcatat
     8341 ccaaatagct gataaaggtg actagattcc caactgtaat ctgcccttcc tgaaccatca
     8401 aggagccaac caaaagcgtt aaaacatagg acgaaccaac aaacacgaga accatagggt
     8461 caaagagact atcatatttc atggtttgca ggttcttttg gaaggttaat tcattgactg
     8521 cctgaaaaga cttcaactcg tctgcctgat aaccgaaaga cttggtcact ttgatacctg
     8581 atacggactc ctgtaccttg ttattgagtt cagaaaaagc agcttgggat tcgccaaagg
     8641 ccttatgagt ctttctccct aggcgactag tcgcataggc catgaaaggt agggggagaa
     8701 tggcaacaag agtcatctgc catgagatgc taaagagcat ggtcaacaaa gtcaccagag
     8761 ccgtgataga ggcatccacc gcagacatga caccgccacc tgctaaacga gtcaaggcat
     8821 tgatatcatt ggttgcgtgt gccatcagat cacccgtccg ataggtttga taaaaggctg
     8881 atgacatttt tgtgaaatgc ttaaacaagc gagaccgcat gatctgtccc aagcaataag
     8941 aggtcccaag gatatacata cgccacacat agcgcaaata gtacatacca aaggctgcaa
     9001 gtagcaagta aaataggcta agaaggaggt cctgctgggt taattgcccc gatgtgatgg
     9061 catcaatgac ccgccccata accataggag gaatgagatt gagaacggaa accaagacca
     9121 gggccacaat cccgactaga taacggcgtt tttctaactt gaaaaaccac caaagttttt
     9181 gaataatgga cataaaatcc ctttctgatt gcaaatggaa acctgaggcc aatactcaat
     9241 gaaaatcaaa gagcaaacta ggaaactagc cgcaggctgc tcaaagcact gctttgaggt
     9301 tgtagataga actgacgaag tcagtaacct acatacggca aggcgacgtt gacgcggttt
     9361 gaagagattt tcgaagagta caagacccca ggtttttctt tttcataagt tacgactgta
     9421 acagcaccct tgtcatattc agcaataaag atattggcta cattgtcatg cccttgttta
     9481 ctgaggttat caagcaacca ctcttcgcta cgaccaatcg attccaagac atctacttga
     9541 atcacaccgt cagtcacaac tggatactta ggattttcat ctcccatttg cacaacgata
     9601 agttgcccat tttgctcttg cacagctcgt ttgacttgct tcatctggaa aatcccttgg
     9661 ctacgaagtt tgagggctac atccgatgca gacaaaccaa ctgaacgaca ggcttctggg
     9721 tcaatattcc catttttgat aaggagagtt ggcttaccat caatcaaacg tttcacaaag
     9781 tgaacattgt tgttgagcca tttgagagtc aagaccagtt tgattaaaat ttcgatataa
     9841 ttaagtgtca tttgttcaca tccaccagtt caattgcgtc tgtcttatac aattcgactt
     9901 tctctaacag gtacttgtct ggctcacttc cgtttagggc acgataatag cgatctccca
     9961 ccttgataag tgcgccatct gtgtttgtgg aagtattaac atagacttct gacttgtcta
    10021 ctcccaaatc tttggaaaca acctcgatga aatgaagtga agtttgaaat ttattgttag
    10081 aaacttgatt gttttgataa gtcgtgatgc tgaccaaaag cagagctaaa taaggccaga
    10141 gctgaaatca tgaccaactc acgaaattcg gttccctttt tatcatggta tgccttgaaa
    10201 gcaaaaaaaa ctgtcacagc taatagaaca atcccaaagc caaccatgat accattttgc
    10261 tgaccgattt ggctgagtac atagtcataa gagtagaatt tcatatattt tcactccctt
    10321 tcataaaatc attcttaatt ataaacgaaa gagagtaatt tttcaaacca tacgttgggg
    10381 aaatagatct ttttttggta taataaaatc tataatctga atgaaaaagg taactttatg
    10441 aaacttatct catggaatat tgattcccta aacgctgccc taactagtga ctcagctcgt
    10501 gccaaattgt cccaagaagt cctacaaacc ttggtcgctg aaaatgctga tatcattgct
    10561 atccaagaaa ccaagctttc tgccaaagga cctacaaaga aacacgtgga aattttagaa
    10621 gaactcttcc caggctacga aaacacatgg cgctcttccc aagagcctgc ccgtaaaggc
    10681 tatgctggaa ccatgttcct ttataagaaa gaacttacgc ctacgatcag ttttccagaa
    10741 atcggtgccc cttctaccat ggacttggaa ggccgtatca tcactctaga atttgatgca
    10801 tttttcgtaa cccaagttta cactccaaac gctggtgacg gtctcaaacg cttggaagaa
    10861 cgccaagtct gggatgttaa atatgctgag tatttggctg aattagacaa agaaaaacca
    10921 gtccttgcga ccggtgacta caacgtagcc cacaatgaaa tcgaccttgc aaatcctgct
    10981 agcaaccgcc gttcacctgg atttactgac gaggaacgtg ctggatttac caaccttttg
    11041 gcaactggat ttacagacac cttccgccat gttcatggcg atgttcctga acgctacact
    11101 tggtgggcac aacgcagcaa aacttctaaa atcaacaata caggctggag aatcgactac
    11161 tggctcacaa gtaaccgtat cgctgacaag gtcactaaat ctgatatgat tgactcaggt
    11221 gctcgccaag accatacacc gattgtcttg gaaattgact tgtaaggatt ttctatatgg
    11281 actacaatgc ggtcattccc gagtttcttg tatcgaatat cgaacagtcc cggtccttct
    11341 actgtggttt actgggtttt aggattgaat actaacgtcc agaagaaaac tttctctttc
    11401 tcttgaagag tgtcaactaa tgttagagga gggaacaaag gatcaactag ctgaactgac
    11461 ctaccccttt ggtcgtggag tcaatctctc ctttggcata aaggatgttc caaaactcta
    11521 tcaaaaagtg atggaggcaa actatcctat ttatcgtctc ttgaccaaaa gaaagtttcg
    11581 tgtcagtgat ccctatatct atcctcataa atttgcagtt ttggatccag atggctattt
    11641 tttaagattt agcgagtaga ataataaaaa ttgggaaaag tctttaaagt tagaaaaagg
    11701 catattgtca ggtgtctaaa aacttgatag tatgcctttt atgatggaaa aatcttctaa
    11761 tactcttcga aaatctcttc aagccacgtc aacgtcgcct taccgtaggt atatgatact
    11821 gactctgtca attctatcca caacctcaaa acagtgtttt gaggttgtgg atagcttcct
    11881 agtttgctct ttgattttca tttagtataa atgttagctt acaatgaagt ttttgttcac
    11941 cctctcttct ttttgttcgc tttttaaacc aaaacactaa caaaatagtt gatttctaaa
    12001 gttatttagt gtaaaataaa aacattggct caagcctatt taaaattgaa tatcgtttta
    12061 cttgtttatg tcgtgaattg gcacgacgtt tctacaaggt gccggaacac ctaacaataa
    12121 gtaagtcagc agtgagatat ggccgttttt gccatgtcta tttaggggac ttacttagag
    12181 attaagtagg tcttttttga atatttttaa tatttccctt aattagtgcg gacgggaggt
    12241 gaaattatcc tgtgaataat ttcaggaatc cagggaattt catccctaat ttttgagccc
    12301 ctagctcttt catttctagg cttaggctaa aatagttccc cgaactattt tactctcaaa
    12361 aatcccgtca tagacaataa caagattatt gtctatgata ccactacaac gggaaatatt
    12421 tgataagact cgcttcgctc gtaatagttt tatcaaatat atagtattag caaaagggat
    12481 cactatagaa atatttaaac aacaagtaaa ttaactttta gactttagga ggtcttatga
    12541 aattattaga agagcgcatc ctcaaggatg ggcatatctt gggtgataac atcctcaagg
    12601 tagattcctt tttaacccac caagttgact ttagcttgat gcgagagatt ggtaaggttt
    12661 ttgcggaaaa atttgctgct actggcatta ccaaggtcgt aaccattgaa gcgtcgggta
    12721 ttgccccagc cgtttttaca gctgaagcct taaacgttcc catgattttc gccaaaaaag
    12781 ctaagaacat caccatgaac gaaggcatct taactgctca agtctactcc tttaccaagc
    12841 aggtgaccag cactgtttct atcgctggaa aattcctctc accagaggac aaggttttga
    12901 ttatcgacga tttccttgct aatggccaag ctgctaaagg cttgattcaa atcatcgaac
    12961 aggccggtgc cacagtccaa gctatcggta tcgtgattga gaaatccttc caagatggcc
    13021 gtgatttgct tgaaaaagca ggctaccctg tcctatcact tgctcgcttg gatcgttttg
    13081 aaaatggtca ggtcgtattt aaggaggcag atctctaatg caaactcaag aaaaacactc
    13141 gcaagcagcc gttctgggct tgcagcactt actagccatg tactcaggat ctatcctggt
    13201 tcccatcatg attgcgacag cccttggcta ttcagctgag cagttgacct acctgatttc
    13261 tacagatatc ttcatgtgtg gggtggcaac cttcctccaa ctccaactca acaaatactt
    13321 tgggattgga ctcccagtcg ttcttggagt tgcattccag tcggtcgctc ccttgattat
    13381 gattgggcaa agccatggta gtggcgctat gtttggtgcc cttatcgcat ctgggattta
    13441 cgtggttctt gtttcaggca tcttctcaaa agtagccaat ctcttcccat ctatcgtaac
    13501 aggatctgtt attaccacga ttggtttaac cttgatccct gtcgctattg gaaatatggg
    13561 aaataacgtt ccagagccaa ctggtcaaag tctcttgctt gcagctatta ctgttctgat
    13621 tatcctcttg atcaacatct ttaccaaagg atttatcaag tctatctcta ttttgattgg
    13681 tctggttgtt ggaactgcca ttgctgctac tatgggcttg gtggacttct ctcctgttgc
    13741 ggtagctcca cttgtccatg tcccaactcc actctacttt gggatgccaa cctttgaaat
    13801 ctcatctatt gtcatgatgt gtatcatcgc aacggtgtct atggttgagt caactggtgt
    13861 ttatctagcc ttgtctgata tcacaaaaga tccaatcgac agcacgcgcc ttcgcaacgg
    13921 ttaccgcgca gaaggtttgg ccgtacttct cggaggaatc tttaacacct tcccttacac
    13981 cggattttca caaaacgttg gtttggttaa attgtcaggc atcaaaaaac gcctgccaat
    14041 ctactacgca gctggtttcc tggttctcct tggactgctt cctaagtttg gcgcccttgc
    14101 ccaaatcatt ccaagctccg tcctcggtgg tgccatgctg gtaatgtttg gttttgtatc
    14161 aattcaaggg atgcaaatcc tcgcccgtgt tgactttgct aacaatgaac acaacttcct
    14221 tatcgcagct gtttcaatcg ctgcaggtgt cggtctcaac aacagtaatc tctttgtcag
    14281 catgccgaca gccttccaaa tgttcttctc aaacggaatc gtcgtagcca gcctactcgc
    14341 tattgtcctc aatgccgtat taaatcataa aaagaaataa gaaaaagagg tgcgagcctc
    14401 ttttttgttg acaaaataaa aacatctacc tattcatata tgctagtgtc atagtcctga
    14461 aaatcatctg catcaagaac aatttcacaa ctcttatact tttctcttac aagtcgttcg
    14521 gcttcatctg gattttcagc ctctatactt actaaacgtg ataaagtttc tgtaatttct
    14581 actgtatact ttttcagttt tagattgctt tccaataatt cacctattaa caataatcta
    14641 tgataggagc tatgtagcca ctctggcaat ttatctccta cttcccaccc atatttttcc
    14701 ttcatcaaag ctagttgttt ttcgtcacca aatttcatat tttcagataa ccatctcaca
    14761 caatcgggat ctgataaggt acagacgatt aaacttaggt tatcgtaacg gctttcagtt
    14821 tcataatcag gccagatgac ttttaagaaa tcatacacct cttctgatgc aacaagttgt
    14881 ttcgttttca taatttccga tactttcctc tacctttaaa ttctattatt tctttgtctc
    14941 ttaatatttg aagctgttgc ctaatctttt ctttgatatg attgttctta acaaagatat
    15001 tttttaggtc actttcaaaa cgatacatat cttcaagggt aaattctgaa ccctctatct
    15061 tatctataca atttagaatt tctattgtcc aacctcttga tgacagagag ctcttcctta
    15121 aaaataaacc ttgcttaaat tcttttgtaa ctttttctgg atctctaact tgtccatctt
    15181 gcacaagaaa tatccttcct ttagaaggta cttgtgataa atcaatgtta caaccaatcc
    15241 aacctgctcg tctagcagtt ggtgcaagtg gttttctttg aataatcgat ttcggtgtaa
    15301 caaattgctt cggaaggaca agaaagttat ttacctcaaa attttttgtg taagttaaaa
    15361 aaaagaaatt aggattatta tctgcctgca cacgcttcat catcgttgca taagcaccat
    15421 cattgattgt tgatgaaaaa tttccttttt tgctctttag ttcaaactcc tcactacaat
    15481 gattacagta aaaatctgct acaggccgat tattttcaaa atgatttaag ggattgttcc
    15541 cacaattagg gtaataagac tgacgataaa cccaatcctc cgttaagata cgtgcctttt
    15601 ggctattact tttataggtt tctactaatt ctaaattaaa gtgtaattcc atttaaaaat
    15661 tcctcactaa tatgagaact cactcgatat aagcaattaa aatctactat aactagtata
    15721 ccacatatat gtacctatta catttgtatt tcatcactct cttttatatt tccttctaac
    15781 atatctcata aattaaaaat gagtgagata aatttatccc actcaccttt ctttatatcc
    15841 ttacccgtct ttcctcagac ctttggccta tgacaaacat ggtaaaggtt gctttgcaga
    15901 catttctgcc ctcttgattg gtgatatcca catccatcac acaggttgta cggccttgat
    15961 ggacacattc tcctttaatg gtcaatacat cgtcgagttt tcctgcctta aggtagttga
    16021 tagaggattg gagtgtcacc ccatcaagtc ccagcgagat aaccaccaaa ccactgattt
    16081 ggtcacatag cgtgaataga tagccaccat gggcattgcc atagtagttg agcgacgagt
    16141 tcactacttt ggtcgtcacc acaacgtgac catctctcat tttttcaatt tcgtaatttt
    16201 caaaggcaga tatagcgtca aaatgaaagt ctttcatcgt ttcctcctga tatttcaaac
    16261 gacactatga tactactttt tataggactg tgcaaggaga aagctcctag tctagtaaaa
    16321 ttccgacatg ttccacaaag cgcataaagg ctgtctgccc ttgttctgtc tgcttgtaga
    16381 ctcctgcatc ctcaagtaca cgcgcaaaga tagcacccac agagtccttg acgattgcaa
    16441 gggctttttc tttatccgtt aggtctggat gttgggattt gagttggtct gcccactcct
    16501 gatgataatc ggcaactgta acagcttctc ctacaagata gctcgcgact tgctccactt
    16561 cttctttcag acgtggtggc aagattgcca agcccatgac ctcaatcaag ccgatatttt
    16621 ccttcttgat atgttggaca tccttgtggg gatgatagat accatcagga tactctgctg
    16681 aagtctgatt gtctcgcaag accaagtcca actcaaactg tccatcgcgt ttgcgggcaa
    16741 tgggtgtgat agtgtgatgc ggtgtcctgt ctgtctctgc caaaatctgc actgcaggat
    16801 ctgaatactg gcgccattcc tgcaaaatct tatcagccaa attgatcaaa tcctctttgg
    16861 aatccgaagt caaacgtagg acagacatgg gccacttgac aattccagcc ttgacctgct
    16921 caaaaccagc aaatcggaag gccttttgca agggagccaa ttccatagga aatacgtgac
    16981 ggcctccctg ataatgatca tgagttagaa tagagccccc cacaatcggc aggtcggcat
    17041 tagatccagc aaaatatcct ggaaactggt ctacgatagc caacagacgt tcaaaactct
    17101 gacgactaat ggccatggga cgatgctggc catctaaaaa gatacaatgc tcattaaagt
    17161 aagcataggg cgaatactgg aaaccccatt cctgaccaac catttcaaaa cggataatac
    17221 ggtgattgct acgagctggg tggttaactc gaccatggta gccctcattc tctagacaaa
    17281 gctgacactg aggataatta ctagcttgca ccaacttggc tgccacaatc tctttcggat
    17341 ccttttcagg cttagagaga ttgatggtaa tttcaagttc tccataatca gatggaacac
    17401 gataagcgat atttttagca atggccttga gtttgatgta gtcatttttc tgactgagtt
    17461 gataaaaatc ctctatcgct tgctcaggat agtggacata ggtttcccag aagtcacgat
    17521 tgacctgact cggacaagga gtcaccaagt ccatcagttc agtaccaagg atttcacgcg
    17581 cagtctgact atcctcaatc gtctctaatc gaacggcttc ctcaactagc tggtccttga
    17641 ggtcaatcaa tttatccaga ttggtctcaa cttccaaaac accttctccc actcgtgcca
    17701 aaacacgatt ggtcaggtag attcgatcca tttcctcaaa tgaactttca gaaatgacat
    17761 gtgttacaaa tttatctact aaggtcacca tagagcctcc ttttgactag tcaaggacgt
    17821 gagtgccacc tgcaacttca gcgatataga agcttggagc gtatccaact acttcctcgt
    17881 agtgtttgcc tacagtttcc ttaaaggcct caacagtatc tttttgaacc aaggcaatgg
    17941 cacagccacc aaaaccagcc cctgtcatac gagcaccgag aactccttct tgtgcccaag
    18001 ctgtgtgaac aagagtatcc aattccaaac cagttacttc ataatcatgc tccagagaaa
    18061 cgtgtgacgc attcatcaaa cgaccaaatg tttccaaatc acctgcttga agggctgctt
    18121 gagctttaag ggtacgttgg ttttcaagca cagcatggcg agcacgtttc aaacgatttt
    18181 catctttaat caaatagcta tattggtcaa cggcccactc gtccaattca cccagggtct
    18241 gaatatccaa ggcaacttgc aattcttcca ctgctttttc acactcagca cgacgttcat
    18301 tgtatttaga gtccgccaat tcacggcgtt tgttggtgtt catgataaca acgacattgt
    18361 ccttcaaatc aagtggcacc aaatcatact ctaaggtgtt ggtatcaagg taaatagcac
    18421 gttgatcggc ccccatacca atagcaaact ggtccatgat accagagttg actccgataa
    18481 agttgttttc tgtttgtttt ccgattttaa ccaaatcgag acgctctaat tttaaatcaa
    18541 agagatgctc tgccacgact cctgtcaaga gctccaagga tgctgaagaa gacaagccag
    18601 caccatttgg gatattccca taaacataaa aatcaaaacc tttgtcaatc acgtgcccag
    18661 cttcttgcaa gaaatgaagg acaccttttg gataattggt ccagttgtgc tctttttcaa
    18721 acttgaggtc agcgagaggc acttcgataa tgcccttgtc ctcaaagtta gctgagtaga
    18781 aacgcaagac ttggtcgtca cgcttacgag ctgcaccgta agttcccaag gaaatagcag
    18841 caggaaaaac gtgcccaccg ttgtagtctg tgtgttcacc aatcaaatta atacggcctg
    18901 gtgaaaagaa ggtttggtct gcttcttgac caaaaacagc aagaaagtct ttgcgaagga
    18961 cttcagtagt aagatgttgt gccatatgaa ttctcctttg actgtccgtt aagccatctt
    19021 aacgtgtaat cgttttcttt ctattgtatc caaggaattt cccaaggtca atccttttta
    19081 ctaaaatttt actaaaatat cagtaaaaag aagaaaaata tgatatacta acctaatcaa
    19141 ggaggattta tggctacctt aaaagacatt gcacagctag cctctgtctc aatcgcgacc
    19201 gtatcccgtg tcctcaaccg cgaccagagc ctatctgtta cagaagaaac cagacaccgt
    19261 attttaaccg ttgctgaaga gctaggctac accaaacacc tcaagacagg cgagtcccac
    19321 aagcccaagc aaaagattgc cattatccaa tgggtcagcg aacaagggga gctagacgac
    19381 ctctactact accagattcg cctaggaata gaaaaaagag cccaagagtt ggactatgat
    19441 atcttgcgct attttaatga ccatcctttt accctaagcg aggaagtgat tgggattctc
    19501 tgcatcggaa aatttagccg agctcagatt tctgcctttg aagaatacca aaagcccctg
    19561 gtctttctag acagtgatac actttccctg gggcatactt gtattattac ggatttttac
    19621 actgctatga aacaggttgt cgattatttc ctcagtcaag ggatggaccg catcgggatt
    19681 ctaacagggc ttgaggaaac aacagaccaa gaagaaatca ttcaggacaa gcgtctagaa
    19741 aacttcaaaa actacagtca agcgagggga atctatcatg atgaactggt ctttcaagga
    19801 agatttactg cccagtctgg ctatgactta atgaaggagg ccattcagag cttgggagac
    19861 caacttccgc cagcattttt cgcagccagc gatagtttag ctatcggtgc cctccgtgcc
    19921 ctccaagaag ctggaatcag cctgccagat cgcgtcagcc tcatttcatt caacgacacc
    19981 agtctgacca aacaggtcta tcctcccctc tctagtatta cagtttatac tgaagaaatg
    20041 gggcgagcag gtatggatat tcttaacaag gaagtcctcc acggtcgcaa aattcctagc
    20101 ctgaccatgc tgggaaccag actgacatta agagaaagta ccctaaatca agaataggat
    20161 aacataaaaa acgaatagag ttctaaaact cctattcgtt ttttattcga ttacaatcat
    20221 agacttaatt gtcttacgtt catccatatc tttataggct tggtcgatat cttccagttt
    20281 ataacttgaa gtaaagacgc gacctggatt gatatcacca tcaaggacgg cttttagtaa
    20341 aaattgctta tcgtatgttg tagcagaagc tgccccacct gctacagaga tattttgcat
    20401 aaatgtcgaa ccaagagcac gattattata gtgtgggact cctacaaagc ccatacgccc
    20461 tccattatga agaacaccta gcgcctgttc tatagcagcc tccgtaccaa cacattcaag
    20521 tgctgcgtct gctcctccgc cgaggatttc acgcaccttg gtaattcctt cttgaccacg
    20581 ttctgcaaca acagctgtcg cacctgactc catagccatc ttttgacggt cttcatgacg
    20641 gctcataagg ataatttgtg atgctccacg catcttagcc gcgatgacag cacattgacc
    20701 aacagcccca tcaccgataa caacaacctt gtcccctttt tgaacatttg caacacgcgc
    20761 tgcatgatag cctgtcggca tgacatctgc aagagtcaaa agggacttga gcatcccttc
    20821 tgtataatca gaaggttgac cagggatttt aaccagcgcc cagtttgcat agtggaagcg
    20881 aatatattct gcctgaaaat caccccccaa attattacca atatgattgt cgcaagaacc
    20941 gtcaaatcca gcaagacagg catcacactc accacatcca tgtgtaaaag ggacaatcac
    21001 aaaatcacct ggtttcaccg tcgtaatggc ttccccagct tcttcaacaa tcccaatcgc
    21061 ttcgtgtcca ctatttttat gtccagcttt cgtttctgga ttacggtacc tccataaatc
    21121 tgaaccacaa acgcacgcac gaaccacacg aataatcaca tcatccgctt ctattatttg
    21181 cggacgttca atgctagcaa gtccaacctg acctgccttt gtatatactg ctgatttcat
    21241 ttaaaatttt ccttccttat aaagtttaat tttgagattt aaacgattta aagctgtctg
    21301 tagctgagac aagcgctcct ctaatttttg cttttcctct tctaaaatac caagcctctc
    21361 ctctctcgtt tcatctccct tttggtagag cgacatatag tcaactaaac tatctacaga
    21421 gacacccgcc gaacgaaaac acttaataaa ttccagcgct tcgatatcct gatcttgaaa
    21481 atcacgaatc ccagtagcag tacgagtaat cggtggcaca agaccaaccc gttcataata
    21541 ccgaatcgta tccgctgaaa ttcccaacaa atcactggca gatttaatat tcacacgcta
    21601 acctcctctc atttcattca ctgaattcac gctattctaa ctcacttatc ttattatata
    21661 actttgagtt gactccaagt caagcatttt gtatctaatc gaaaaatttt tatcattaac
    21721 aatcatatat ctggagttta tacaatgctc ttctcttacc aatttttgaa atatttaaat
    21781 aataaagaaa ttactctatt ccaaataaga tagtacccaa gtatttttca cttttttcta
    21841 atgttgatgc tcataactcc gttccaagtc acacaccttt cgcttatggg tttggtgagt
    21901 ttctaggtca gcatcaattt caatggtaat attttgaaaa ccacaatctt ttaggaaaat
    21961 tcgaatagac tctttacaag tttccatatg ttccatttct tttagacaaa catgtacaat
    22021 ggcatttttt tccaaagcat ccatagtcca gagattaagc tgattaaggc tggccacatt
    22081 gtccaatcgc tccaggccac tctttacttg cttgatatca agaccttctg gcacagcatc
    22141 caagaaaatc ttgagtgtag accaaaaacg tggaagggct tttgaaagaa taaagaaaga
    22201 aatgacaagg gacaaaagag gatctaggat ataccagtcc gtaaatcgaa gaacaatcgc
    22261 catcaggata acagctaccc accctagcgt atcttccaga aaatgcaaac tcagaataga
    22321 ctcattcttt gtctttccct taccaaccac cagactcgct aacagattga tagtaatcgc
    22381 aataattcct aaccagagaa tcccctcatc attgactggt tgcggatgca aaatcttcgt
    22441 gacattttcc aaaatgacta gaacagagcc cgttacgaga atcacagctg ttaccaaggc
    22501 tcctagcagg ctaaaccgct tatagcccaa ggtgtactga ttgtcttctt cacgattgga
    22561 gattgtttct agaaaagctg atattccaat tgcaatcgca tctcccaagt catgcacaga
    22621 gtcagcaaga acagcgctag aaccaaatac tccacctgca ataaactcaa caatggcata
    22681 agtcaaattt aagaaaaaag ccacccaaac agcatatttt gccttcatat ttctcattcc
    22741 tttgttataa tagatttatg aacaccttgt tcattatcat tatccactaa aactcaaaga
    22801 aaggatagaa gcaaaacgtc agctttattc agttctgaac aatttgcctt aagtgtccat
    22861 atgactaaca ttgaccgccg tatcagcaaa accaaaaaag ccatctatca agcttttata
    22921 caacttttga atgctaaggg ctacgaggcc actactgttc aggatatcat tgatctcgca
    22981 gatgtgggaa gatccacctt ttactgtcac tatgaaagta aggagcttct tctggaccag
    23041 ctctgccgct acctcttcca tcatcttttt gaaagagagc aagccatttc aaccgaggac
    23101 tacctcgccc acctctttct ccattttcag aaaaaccaag accatatcac cagtctgcta
    23161 ttttccaaaa atgactactt cctccgtcaa ctccataaag agctagaaca ccatgtctat
    23221 tccgtgctag ctgataattt aaaagaagcc caccctaata tgcctacttc ttacctccaa
    23281 cacttggtcg tgtccaactt tatcgagaca ttgacctggt ggctcaaaaa aggtcaagat
    23341 ttcataggcc aggaagttgt ccaattttat ctagaccttc tcattcctaa aaattgaata
    23401 tagagtaaag ctcagttgtc ttatttctag gttactgagt tttttatctt ttcaacaaca
    23461 aaagaggacc cgccgatcct ctttttcata ctataaatcc ttgattatca actatatctg
    23521 ttttaatcga aatctcaaaa cagcactttc aaacatcttt tcctagttaa gtaaatcagt
    23581 attctgctta gctgccttgc tccattgata ccaaccaact agactgttaa tgagataaat
    23641 tagatatttc ccttgaattt gcaggctttc tccccaccag agatagattg aaaaaacatt
    23701 ggtagccgcc cagaatatcc actgttcacg gtaaacagct gtcatgagga tttgccctac
    23761 cccattggtt gcatctgtga ttgaatcacg atagggacga ttggcaccaa tagactgata
    23821 aatgaagcca aaggccaacc accaaagcac actaatggaa agatactttg tccagccctt
    23881 gccgtccagt ttacgcgcga caaactcctg cttttccttc ttaaactgtg cctgataaat
    23941 ccaaactaga agtccaattg gctgcatgac tgtgaagtaa agtgtcgtca gcacctcacc
    24001 ataaaagcct ttctgtaggg ccaaaataag gtaaataaca gagttaatca agccaaaaag
    24061 ataattactt gctcgacctt ccgatacaaa gattacacag ataatccctg tcaagctaca
    24121 aatcatccca atccagtcaa caatacgatg ttcgtaaacc aactccagcc agagaggaaa
    24181 acttcctaaa accagcaaat aaatccactg ggcaaaacta cgatgggcaa agaggtcatc
    24241 ccagatagcc ttcatagttc ctgaaaatcc taaatcagcc atagccgcaa ccatacgacg
    24301 gtaaccacct gacatttcac ctagggttgt tttgatattt tcaattttct tttgcaaata
    24361 agtatgcatc atttctcctt ttgtttttaa agagccgtgt ctggatagac tttcggacgc
    24421 aacgctctat tagataatga actgcctata cacaagattt ctaaccttag tcgacatgag
    24481 ctaaaacctc ttatttgtta agtagttcac aaaatattat acacctattt tatgaatagt
    24541 caactgtctt tacagtaaaa ttttagaaaa tcatgaaaat tttctctttc tttccatttt
    24601 aagtgacatt cagtcattct cacatcaaaa aagcccagac gaaattgtct gagcattctt
    24661 ttatctagtc gtttaaggaa gttgagttca gtatgtttaa agtctctgtc ccatcatttc
    24721 ttcaacaaac cttgttcttg gagaaactcc ttggctactt gctttgctga cttgccttca
    24781 acaccgactt ggtagttgag ctggctcatc tggctttctg taatcttacc agccaatgta
    24841 ttaagaactc tttccaactc tgggtgtttc ttgagaagag cttctttcat gagtggagcc
    24901 ccttgataag gtgggaagag ttgcttgtca tcttccaaga cctgtaaatc ataacgctcc
    24961 aattccgcat cagtcgaata ggcatccgtg atttgaatat cccctgactg aattgcctga
    25021 taacgaagag ctggctgcat agtcgccaca ttgagattga gaccatacat tgattgcaag
    25081 cccttatttc catcttcacg gtcgttaaac tcaagcgtaa agcctgcctt cagctgccct
    25141 tccacttttt tcaaatccga aatggtcttc aagccatatt cttgcgcaat ctttttcgga
    25201 acagctacag cataggtatt ttgataagac ataggtttga gataggctag atgatcctgc
    25261 ttggcaatgc tatcacgcgc cacttgataa acctgctctg gctcatgact caccttgggt
    25321 gatggttgaa gcaaactttc agtcaccgta ccggtaaatt caggataaat gtcaatatca
    25381 ccttttttca gagcttcata aaggaaactt gtcgtcccaa aattcggttt aacagtcgca
    25441 gtcatgctgg tattttcttc aatcagcaat ttatacatat tagccaaaat ttctggttct
    25501 gggcctattt tcccagcaat aatcaagttt tccttctctt tttgagccaa aagggctgga
    25561 ctataagaca gacccagtaa taaagccacc aaggcaaaac cagagaaaat cgtccgcaat
    25621 ttcgcttttt ccattacttt tagtaggaag ttaaaggcaa tagctagcac tgcagaagaa
    25681 agggccccaa tcaaaatcaa actggcatta ttacggtcaa ttcccaacag gataaaggaa
    25741 cccagtcccc ctgccccaat caaggtcgcc aaggtagccg taccgataat caagaccgct
    25801 gccgtccgaa ttccagacat gataacaggc atggcaagtg gaatttcaaa cttcttgaga
    25861 cgctcccatc tggtcatccc aaaggcaatc ccagcctctt gaagactcgg atcaattccc
    25921 ttcagcccag taatagtatt ttgtaaaatc ggaaaaatcg cataaatcac tagagctgtc
    25981 aatgccggta aagtcccaat tcccatcaag ggaataaaga gtcccaacaa ggccagagac
    26041 gggatggtct ggaaaatccc tgcaatctgt aagacccaat ccgccaactt ctcatgatag
    26101 cgaagaaaaa cagccaaggg aatcgcaagc aaaatagcta gtaacaaggt caaaagtgac
    26161 aactgcaaat gttgagatag agctgtcaac caatcactaa aacgatcctg aaaagttgca
    26221 attaaattag tcatgaacac tacctccaaa caagtctgct acaaagtctg ttgcaggcgc
    26281 ttttaaaatt gtctcgggat tcgctacctg gcgaatttct ccatcctgca agacagcaat
    26341 acggtccgcc aacttcaagg cttcatccgt atcatgggtt acaaaaatcg ttgtcatccc
    26401 aaactcttta tgcaattctt ttgtcagaac ctgcaactgt tttctcgaaa tagcatccaa
    26461 ggccgaaaag ggttcatcca tgaggaaaat cttgggctga ccaatcatag ctcggacaat
    26521 accgacccgt tgctgttctc caccagataa ttcactaggt aagcgatgcc catactcggc
    26581 tactggtaaa ccaaccttag ccaaaagctc ttctgttttc ttcgtaattt cttccttgct
    26641 ccaccccttc atttcaggaa tgagagcaat attttccgca actgttagat ttggaaaaag
    26701 agcaatagcc tgtaaaacat aaccagtaga aagacgaagt tcacgctcat catagtcttt
    26761 gatgcgcttc ccatccatat aaatatttcc atcagttggt tccaaaagac ggttaatcat
    26821 cttgagcatg gtcgtcttac ctgacccaga aggccctact aaaaccataa attccccatc
    26881 ctcaatctgt aagttgacat ctctcaagac atccttttct gtgtagcata gtgctacatt
    26941 tttgtattca atcattcttt gtcctcattt aaaacttccc tcgattggtc aagtcttcta
    27001 ccttaggcat gacttcctta ttatcccaat gctccacaat tttcccgttc tttaaacgga
    27061 agatatcgta ctgggcataa gcaacgccat caatctgagt ctgaccatag ctaaccacat
    27121 agtttccttg tcctaagagt tggaaaacaa agtcaaaagt gacactatat tcagccacat
    27181 agtttttata agcagcactt ccttgtccaa tatcatgatt atgctgaatc aaatcgtctg
    27241 ccacataatc actccactgc tctagctccc cattttggaa aatttctgtc aagaaacggc
    27301 gaaccagctt tttattttct gctttcttgt ccaaatcctt gatttcaaaa tctccaaaaa
    27361 tttgatctag ttggtcattt tcaggtgttc gatagtagtc aatgacatcc caatgctcaa
    27421 caatacgacc attctcatcc gcacgaaaag tatccgtcgt cacccattga gcttctccac
    27481 cattcagata ttgatgaaca tgaacaaaga ccagattgcc atcctcaatg gtgcggacaa
    27541 tcttaatctg acgctctgga tgacgctcaa agaaatctgc aaagaaggct gcaaatcctt
    27601 ctttcccgtc aggaacacct gtcgaatgtt ggatataggt agcccctaca gactgggctt
    27661 gagcctcagc aactcgtccg tcttgaatgg catggatgta taggttgtga gcatttttca
    27721 cttgttgtga catattctaa acctcatttc ccttctcttt cagattcgcc aaaattcttt
    27781 cttgaaaacc ttcaaattgg tgaatttctt cctctgaaaa tcctttgtaa aagatagtat
    27841 ccaatttctg actgacacga tgccccactt ctttctggga cttgcctaac tccgttaaaa
    27901 ctaaatactt cttacgcttg tcttttccac acggactaac aattacaagc ttttgttcct
    27961 ctagcttttt tatcatagtc gtcagcgtat tattcgcaag tccagtcgca agcgcgatat
    28021 ctgtcgcagt tgcgcagcca gtttcactat tccataaaac cgctaaaatc ttgccctgtt
    28081 cacccctata aagagcctca ggatcttgac tcagtaactt ttgaaaaatc cgcccattca
    28141 acaaacgaat atgatgggct agcaaatgac catctttcat aacacctcca atttatttcg
    28201 atatcgaaat gaataaaaca attgtaacac tcatcgttct aactgtcaac tatttcgatt
    28261 tagaaataat ttttgataat tatccacacc accatactcc ggctcaacta acttttaacg
    28321 agagtttcta aactccttcg tcctccagtc tacaaaagcc ttccatccgt actatcctat
    28381 attttatgag gggacacatt tttcctatca gaccatttat tttaaagata gaagtaaatc
    28441 ataattgctt ccatctgttc ttttatagta tattgaagtt ggactagggc actgtatctt
    28501 ctaaaacatt gatagaaagc gatttgaatt tcccaatcaa tttgttcgtc tttatagcat
    28561 ttcgaaactg gaataggaca ccatgactgc taaaagattt ctataaattc atttgatttc
    28621 ctcaatcaat ttgttcatat cttatttcat tccgctataa tttcacctta ccctatcttt
    28681 ttcgtagcac ccttcaaaca gcctatcccc taccgtttga cgattcctca cttcactcca
    28741 cttccattac agaagtttct tcactactat ggtctcggct gacttctcat gattccttgt
    28801 tactactatt tgaacgctca cgagataggt cttataaaaa atgctttgat ccacaatgga
    28861 atcaaagcat tttaaaaagt tcctcataca taagtgcaga agtcgcagtt cctctgtact
    28921 tggcttcttc tcttttgata aagcgagcca agttgagcaa ctcaggtgct ggatgtttgg
    28981 gatttaggag caattcacga ttgaccaggc ctgagagacg aactgcctgc aattgctcat
    29041 ttgtagtagg cagtttttta gtagtctcta ggagagcagc aactaaatct tcactcaaat
    29101 catgtcgagc atgattgtaa agatctttta taaggctttc taggtttggt tctgccatcc
    29161 ctaccacctc ccttatggtt taataatgtt taatcaaatc aaccgttgaa cgatccaatt
    29221 tcttcaccaa ggcttgtaag aaagcttgcg cttctaggaa gtcatccatt gcatagaggg
    29281 tttggtgaga atggatataa cgagcgcaga caccgatagt tgttgatggg acaccaccat
    29341 ttttcagatg agctgcacct gcatctgttc cgcctttacc acagtagtat tggtacttga
    29401 taccagcttc ttcagccgtt gtcaaaagga aatccttcat ccctgggaga agcaagtgac
    29461 ctggatcata gaaacgaatc aaggttccat ctccaatctt gccttgacca ccgtagacat
    29521 cacctgctgg tgagcaatca actgcgagga agacttctgg gtcaaacttg gttgtagagg
    29581 tatgagcgcc acgcagacca acttcttctt ggacgttaga acccagatag agttcattgc
    29641 cgagtttttg acctaataaa gcttcagcta gctcgcttac catgaggaca ccgtagcggt
    29701 tatcccaagc ttttgagatg atattttttt cattggctgt caaaattgca gaactatctg
    29761 gtacgatggt atcaccagga cggatgccaa aactttctgc ctcagccttg tccgcaaaac
    29821 caccatcaaa aacgatatcg gcaatggctg gcatggttgg tccccccttt ccacgagtca
    29881 aatgcggagg aacagaacct gaaatcacag gaatttcatg accatcacga gtcaagagtt
    29941 tgaaacgttg gctgctaacc accatggggt tccagccacc gatttctacg acacggaagg
    30001 taccatctgg cttgatttcg ctgaccataa aaccaacttc gtccatatga gaagcgacca
    30061 agacgcgcgg tgcatccaca gcttctgaat gtttgatacc aaaaatacca cccaagccat
    30121 ctgtcaccac ttcatccaca tgcggtgtca acttttcacg aagataagca cggacaggcg
    30181 cttcatgacc tgagactgca gcaagttctg ttacttcttt aatttttgaa aataatgttg
    30241 tcatttcagt tccttctttc tttcatccat tttaccactt tttataggag aaggatagtg
    30301 ggaaggtgga tttctaagtt agtatcttag tcctgctcta tcttagaaaa ggatagtatt
    30361 ctcttgcatg tagtgcaaaa tctagtaaac attccaaaat taactcgaat atttatttcc
    30421 aaacaaaaaa acaatacacc atcaaagttg tttggatttt tcatgaaatt tacagaaaat
    30481 agttgacttc cctttcttct ttctttaaat atatagttgg ttgagtttgg aatagtacgc
    30541 tgtagctgct aaaacatttc tagaaattaa tttgactttc ctaatagagt tgttcatatc
    30601 ttatttcaat ttactatagt acaaaactag aaaaggaaaa aatcatgacc aaaacaattc
    30661 ttgttacagg tgggactagc tacattggct cccataccgt taaagctctt ttaaatgctg
    30721 gctatcaggt gcatgtcctc gataatctct ccacaggaaa tcgagcggct gtggatagtc
    30781 gtgctagctt taaagaactg gatgtttatg atgctagcgc cttaaaggct tacttagaag
    30841 aaaatcagat tgatgctgtc ctccattgtg caggtgaaat tgttgtgagc gaaagtattg
    30901 aaaatccaag taaatacttc actgccaacg ttgctggtat ggaccaagtt ctcaaagtct
    30961 tatctgaagt tggcattcaa aaaatcatgt tctcttcgac tgcttctctc tatggaaata
    31021 actgtattga caagccggtg actgaagata ccctgctcga ccctgtcaac ccttatgcag
    31081 agacaaaact gatgggcgaa cgaatgattt actggatggc caatcgctac gactggaaat
    31141 atgttatttt ccgttacttt aatgttgctg gggctgaaat ggatgcttca aacggtctgc
    31201 gtgtgaaaaa tccaactcac atcattccaa atatcaacaa gaccgcattg ggacaacatg
    31261 atagcttaaa aatatttgga gatgactacg atacacgtga cggttcatgt attcgagatt
    31321 acatttatgt cttggacctt gcataggctc atgttaaagg aatgaactac ctatttcaag
    31381 aagacagttc ttctcaaatc tttaacttag gaactaaaaa aggctatact atcaaagaaa
    31441 tctttaaaac tgctgaagaa ttactaaatt aaaaaatccc acacgagatt gttgctcgac
    31501 gtgctagtga cccagccagt gtcctagcag atgcttcaaa agctaaacaa tatcttgatt
    31561 ggacggctag ctactccctc gaagatatta ttttatcaga ttaaggtaaa aacattttag
    31621 aataggataa caaaggagaa agtcttgttg ctctctcctt gttgtattta ttaaattgtc
    31681 agaaatttta ttgacagatt agaaaaataa tgttacattt atatccgcag gtatctttcg
    31741 ataccaaatc tacatgaaag gacggggtat gaaactttct cattatttaa ttggcttact
    31801 tctactccta gtctttctct ctattagcat tgggaccagt gatttttcat ggggaaagct
    31861 atttgatttc gaccagcaga cctggctcct ctttcaagag tcccgtctcc caagaactat
    31921 cagtattctc ctgactgcct ctagtatgag tatggcaggc cttctcatgc agactattac
    31981 ccaaaatcag tttgctgcac cgagtacagt tggaacgact gaagccgcca aactgggaat
    32041 ggtgctgagc ctttttgtct ttccatcggc tagtctgacc caaaagatgc tcttcgcttt
    32101 tatttcatcc atcgtattca ccctcttctt cctagccttt atgaccattt ttactgtaaa
    32161 ggaaaggtgg atgttgcctc tgattgggat catctatagc gggattatcg gctcagtcac
    32221 agaagttatc gcctatcgtt tcaatctggt tcagagtatg actgcctgga cccagggctc
    32281 cttctccatg attcagaccc atcagtatga gtggctcttc ttaggcctca tcatcctgat
    32341 aaccgtttgg aaattatccc aaaccttcac catcatgaat ctagggaaag aaaccagcga
    32401 gagtttgggg atttcctact ccctacttga aaaactggcc ctctttctgg tggcgctaac
    32461 gacaagcgtc accatgatta ccgtgggtgg cttaccattt ctcggagtta tcgttcccaa
    32521 tcttgttcgc aagcgctatg gagataatct aagtcaaacc aaactcatgg tcgcactggt
    32581 tggtgccaat ctagttctgg cttgcgatat cctatcccga gttctgatta ggccctatga
    32641 gttgtctgtc agtctcttgc taggaatcat cggtagtctc gtctttatcc tacttctctg
    32701 gagaggggga cgaaaagatg cagactaaaa gcaaacatac caagctcttc tggattctca
    32761 ttattcttgc catcggagct tgtcttctct acttttggcc catcactcac ttgtcagcct
    32821 ttgcttggaa gttgcgttcc caaaagatca tcgtttatct cttggtagcc atcgcgactg
    32881 ggatttcgac cattagtttt caaaccctga cggaaaatcg cttcctgacg cctagtattt
    32941 tgggaattga atccttctac gtcctactac aaaccctact actggttttt gaaagcaagt
    33001 ttcttcaact tggcaaatcc cctatcttag aattcctagt cttacttctt gtccagtccc
    33061 tcttctttct cgccttacaa ggttacttga agacactgat gaagcaagac ctggtcttca
    33121 tcctgctgat ctgtctagcg ctcagaagtc tctttcgaaa tatcagcacc ttccttcaag
    33181 tcctaatgga tccaaacgaa tacgataaac tgcaaaatag tctttttgcc tcctttcaac
    33241 atcttaacac ttccatccta gccatcggtt ctctgatcat cctcgctttg acaatctttt
    33301 tctttcgaaa agcagtcgtt ctagatgtct tgcacctgca aagagaaacg gctcagatat
    33361 tgggactcga tgttgaaaaa gaacagaaag agctcctctg gggaatcgtg cttttgacct
    33421 caacggccac tgccttggta ggacctatgg ccttcttcgg ctttatgctg gccaacctca
    33481 cctacctgat tgtcaaagac tatcagcaca agttactctt tatagtggcc attctggttg
    33541 gatttattag cttaaccttg gggcaagcct tgattgaacg agtctttgca ctggaaattc
    33601 gtatcagtat gatcattgag agtgtgggtg gcttcttatt ctttatctta ctatatagga
    33661 gggctcgtca gtgaaactgg aaaacattga caaatccatt caaaaacagg atattttgca
    33721 aggcatttcg cttgaagtca gtcctcaaaa actgacagcc tttattggtc caaatggtgc
    33781 tggaaaatcg actctcctct ccatcatgag cagactaacc aagaaagatc agggagttct
    33841 cagtatcaaa ggacgtgaaa tcgagagctg gaattcgcaa gaactggccc aagaactaac
    33901 catcctaaaa cagaaaatca attaccaagc caaattgact gttgaagaac tggtcagttt
    33961 tggacgtttt ccctacagcc gaggtcgact tagatcagaa gactgggaaa aaatccgaga
    34021 aactctgaac tatttggaac tgaccaactt aaaagaccgc tacatcaata gcctgtcagg
    34081 ggggcaactc cagcgcgtct ttatcgctat ggtactggcc caggatacgg actttatctt
    34141 gctggacgaa ccactcaaca atctcgatat caagcaaagc gtcagcatga tgcagattct
    34201 tcgacgactg gtggaggaac tcggcaagac cattatcatc gtcctccacg atatcaacat
    34261 ggccagtcag tatgcagatg aaattgtcgc cttcaaggac ggccaggtct ttagcaaggg
    34321 aagaaccgat caaatcatgc aggctgacct gctcagtcaa ctttatgaga ttcccatcac
    34381 gctagctgat atcaataaca aaaagatctg tatctatagc tagtaacata aaagctcaag
    34441 ttagagaacc ttcagtctct tagtcaataa gattaagaga ctccctaaat cgttatcaca
    34501 ttttaaaaag gagaaattat gaaaacatcc cttaaacttt atttcactgc cctagtggcc
    34561 agcttcttgc tcctacttgg tgcatgtagt acaaactcaa gcactagtca gacagagacc
    34621 agtagctctg ctccaacaga ggtaaccatt aaaagttcac tggacgaggt caaactttcc
    34681 aaagttcctg aaaagattgt gacctttgac ctcggcgctg cggatactat tcgcgcttta
    34741 ggatttgaaa aaaatatcgt cggaatgcct acaaaaactg ttccgactta tctaaaagac
    34801 ctagtgggaa ctgtcaaaaa tgttggttct atgaaagaac ctgatttaga agctatcgcc
    34861 gcccttgagc ctgatttgat tatcgcttca ccacgtacac aaaaatttgt agacaaattc
    34921 aaagaaatcg ccccaaccgt tctcttccaa gcaagcaagg atgactactg gacttctacc
    34981 aaggctaata tcgaatcctt agcaagtgcc ttcggcgaaa ctagtacaca aaaagccaag
    35041 gaagaattgg ccaagctaga caagagcatc caagaagtcg ctactaaaaa tgaaagctct
    35101 gacaaaaaag cccttgcgat cctccttaat gaaggaaaaa tggcagcctt tggtgccaaa
    35161 tctcgtttct ctttcttgta ccaaaccttg aaattcaaac caactgatac aaaatttgaa
    35221 gactcacgcc acggacaaga agtcagcttt gaaagtgtca aagaaatcaa ccctgacatc
    35281 ctctttgtca tcaaccgtac ccttgccatc ggtggggaca actctagcaa cgacggtgtc
    35341 ctagaaaatg cccttatcgc tgaaacacct gctgctaaaa atggtaagat tatccaacta
    35401 acaccagacc tctggtatct aagcggaggc ggacttgaat caacaaaact catgattgaa
    35461 gacatacaaa aagctttgaa ataagccact tcaaactcaa tttaatactc aatgaaaatc
    35521 aaagagcaaa ctaggaaact agccgcaggt tgctcaaaac actgttttga ggttgcagat
    35581 gaaagctgat gcggtttgaa gagattttcg aagagtataa aattttgaca ttctaaaacg
    35641 catcctatca agttcactca aacctgatag gatgcgtttt tatcattttg aaatctattt
    35701 accccacctc attccccttc ttgatttcgt ttaagggaaa agtggtctgg aacggggtcc
    35761 ttacctgttt tcgaccaggg atgacaacgt aaaatccgag ccaagcccat caataccccc
    35821 ttaaaaccat gtttttcaat agcctgaatc atgtagttgg aacaagtcag ctcaaagcga
    35881 caagagggtg gaaagactgg tgagataaaa cgttggtaaa agcgcacaag cgctattaaa
    35941 attcgtttca ttatttctta gttacagcca tggtgtgtag ttggctgatt tcttttttat
    36001 taagacgacg ggattctcct ggacggagtc ctgtcaagtc taggtgtccg aaacgagtcc
    36061 gagacaactt atctacttgg agaccaacag cttcaaacat ctttttaacc tgatggttac
    36121 gcccttcatg gatggtcaac tgcaccacag agcgattttt gactgggtcc actttgagaa
    36181 tttcataaac agctggcttg gttttcttac catcaatctc aagaccacgg gtcaaggggc
    36241 gaagattgtc cttattggcc acacctttaa cacgcgcgac ataaaccttg tcaatctcat
    36301 tacgagggtg aatcatctcg tctgtaaagt ccccatcatt ggtcaaaatc aagactcctg
    36361 atgtatccca gtccaaacga cccacagggt aaatgcgctc tttgacattg ggcaagaggt
    36421 cgacaaccgt cttgcgaccc ttgtcatctg ttacactgga aatgacaccg cgtggtttgt
    36481 taagcagata atagaccttt tcttcgttgt agataggttg accttcaact tcgaccttgt
    36541 cgcctgactt gatagtggtt gctagttcac gcaccacttg gccgttaact gtcaccaaac
    36601 cttgcttgat cagctcttct gcttttctcc tactggccac acctgcgtgg gcaatatact
    36661 tattgattct catcttcttc tatcctttca ccaaataatt ggctttcttg ggcttgaatc
    36721 tcaagctcat caatcactgg taattcttct aaatggttta tccccatgta atctaggaaa
    36781 taatccgtag tcacatagag gttggggcgc cccaatactt cctttttccc gtcttccttt
    36841 atcaggtcca aagcttgcaa ctttgccaag gctccactcg agttaacccc acggatggca
    36901 tcaatttcta tccgcgtaat cggctgtttg taggcaataa tggacaaggt ctcaagggca
    36961 gcccgagaca agctctggtt gataggcgcc ttagagtatt ccttcaaaat ctctgcaaat
    37021 tgaggcttgg tcaccaatct ataagcacca cttgtctcaa tcaaagccaa actggaatct
    37081 gggtcctttt catacttctg ggctaatttt cctaaacttt gctggatgcc tgtcggtggc
    37141 agagagagga gttcagctaa ctggcggacc cgaatcccat cttcacccgc tacaaataag
    37201 agcgcttcta tttttgctaa agtactcatc tttcctctct atcaagtcta gctttgaggc
    37261 acttgacttt cttccttctt ttccatgaga tagatatctc caaaactctc ctcttgcacg
    37321 aggatcagct cctgggtttt gattaactct agggttgcca aaaagagggt gatgacctct
    37381 tggacattct gggcttcctt gaacaaatcc tgcaagcgca attgatctcg tccaatcaag
    37441 gattctttca caataatcat catgtcctca atcttatact catcccgcaa gatagtcgtg
    37501 tgattttgtg caaactcctc ttttttcttg gctaggatat ttgaaaaagc caaaaagagg
    37561 tcaatggtcg tcttgtcatg cacaagctcc gcatcttcgt aaatcaactc tgtcggcgct
    37621 ttggaataat actgggcccg ttcttggtgc ttggcttcca agtgctcacc caagagcttg
    37681 aacttgcgat attcttcgat ttgagagagg aggtcctgct ccaggtcatc ccccaagtct
    37741 gtcacttctg ctaccttcgg aaggagttta cgactcttaa tcagcatgag ctgactagcc
    37801 atgaccatgt actcacccgt cacttccaga cgcatggcct gcagggttga gacataggct
    37861 agatactgtt cgatgacttc cgtaatgggc acatcgtaga tatccatctg gtacttagaa
    37921 accagatgca agagtaagtc caggggtcct tcaaaatctt ttaatttaat atccattatc
    37981 tatatttttc taaggtcagg actgttttta atcctaattt ttttgcaatt tcgtacaaat
    38041 cgaccttgtt ttctatttgt cttagaataa actgttcacg taagacttga gctgataagg
    38101 atggaaaacc tttctccttg acaaaagatt ctaactgacg aaaggcccac tgacgagaat
    38161 agggtttccc tcctctttca aaaagatagg tctgccccat caagggttcc aattctgaaa
    38221 gcaaggccgt gggaatggtg acaatcctcc gttgggaagc cttgctgatt cgcaacacct
    38281 gaaaatccag attgatgtcc gcaaccttga tggctaaaat ctcactgggc aagagcccca
    38341 tttctaggat taagagcgct agcaagcggc cctctggatg gtcgctttcc tgccaaaaag
    38401 agtctaggta tagaatctct ggcttttccg tcttcttttc agcttgtttg gctaattcca
    38461 agcggtaaaa gctgtccacc tctccttttt gatagagaaa gtatagaaat tggttacagg
    38521 ccgaaatctt tcgcttctgg gcgctgattt ttagattggc tagctgggct tggtaaatct
    38581 tgagactggt ctcagaaatc cgctcaccta ccatgtctaa aaattgctcc aaatcatact
    38641 tataggactg cttggaattg acagacaagc cctgcttttc ctctaaaaag gctgaaatcc
    38701 tgtctctcat tggcatcgaa tctcatattc cttactaaag tcatgcaaga gggcattaac
    38761 ggccttgagg atggacttgc gcgtaataat cccttggaaa ataccctctg catccacaac
    38821 cggtaagaag gactcatcta ctagcttgtg caagacctcc gtaatggtga aatcaggcga
    38881 aacaaccgct acgtccgttt ttgtcatatg aacgatatcc gtatccgcca tgatttcttg
    38941 gctcaagtca tgctccatct gataagccat aatatctctg agtccaatcg tcccaacaaa
    39001 ctgtttttca tctgtcacaa cgggaacacg ggtataggtc atctgactga gcaagagggt
    39061 cgcatgatcc gcattgtgag tatcaatcaa cacagctaga tttttagcag gggtcaaaaa
    39121 agtttcctcc tgccccaaca agaaagtctc aaactccttg gcaatcatcg gctaaactcc
    39181 ttggacaaac ctggatacac ctcgtgatct cgtgtcaaaa agtccacttt gaagtaacta
    39241 tcatcaatct ccacacgagc atagagacat tctctgatgg tacctcgtgg ttgactgata
    39301 gagcctggat ttagaaagag gatcttgcct tccaaccaag cacttggcac atgcaagtga
    39361 ccatagaggc agatagcggc ctcttcctcc tgagcccagt agtccaactt ttgaaagttg
    39421 aaattgatgt caaacaagtg accatgagtt tggataatct tggtcgaacc aagctcagtc
    39481 accagacgtt ctgggtagcc ggcgtagaag tccatgttcc ctttaacaac gcggatgccc
    39541 tcccaaagtg gagaatccgg acgtagttca gaatcgccgt tatgaaaaac ggcatcgact
    39601 ttgcccacat agcgatcacg gacttcttcc acaatcaagc tatcgccatg ggaatcgctc
    39661 attacaatga tggtttgctt tgccatgatg gaaatacctc caaaagtttc ttaacggcta
    39721 aggcacggtg agattgacta tttttttctt ccagggttaa ttcagctgat gactcacctg
    39781 tctctcctac aaggaagagg ggatcatagc caaagccatt ttcaccctta ggttcaaagt
    39841 taatataacc tgaccagtct gcttcaacaa ctaaactttc cttatttggg ctggctacga
    39901 ctagggttgt gtggaactga gccgagcggt ccttgagttc aaagaccatg gccaattcgt
    39961 gcaagagttt ggcattattt tcacggtcag ttgctcccac acctgcgaaa cgagctgacc
    40021 agacgcctgg taagccacca aggacatcga ctttgagacc agaatcatct gccaaaacca
    40081 tcttgcccgt taattgagaa atggtttctg ccttaaggcg ggcattttcc tcaaaggtca
    40141 tacctgtttc tgctacttca ggcaggtcag ggtagtcatt aagattttcc acatcgtagc
    40201 ctaacttatc aaagatagct cggaattcct tggttttacc ttcgttacga gtcgcaatca
    40261 acaaggtttc tctgactttg cttgtctcaa agaaatcatg aacattgacc ccttctttag
    40321 gcaattctac atacaagagt tgcccatttt caaccaagag cagggcccca tgacgttgaa
    40381 taacttccaa gtttcgtccc atttcttgat taagcatatc taccacaaag gagaacaaac
    40441 ggtaggtaga accatagcgt aaaacagtaa ctgaaagcgg gaaaccatac tcttcatctc
    40501 caaatatttt ggagaattca aacagaggaa aatctgtctg atagtcgctc aaactgttaa
    40561 cgccaccaaa aatactataa gacccaacat accagtcctg gtcatcctta tattcataaa
    40621 ttttatttgt cataattcta catgctccac atgaatctct ttttccagcc attcttcacc
    40681 aatttgtgca aaactttggc tactggctgt tgtgtaaaaa cggtgatgga gtggtccagc
    40741 atcgcgacca cgattgattt caaaataatt gagtaagact gagatatccc gtacgcactc
    40801 tgccccacta tcgatgagct gaacctttgg ccccatcaca ttttggataa tagggcgaag
    40861 gagtggataa tgagtacagc ccaaaatcag gctatccacc tttccaacca agggacgcag
    40921 ggtttcatag accaccttct tggtaacact ggttgacagg gcacctgact caaccaaggg
    40981 agcaaacttg ggacaggcca agctctccac ctgtaagtcg ggatccagat catggatttt
    41041 ctgacggtat atgtctgatt gtaccgtcat gggcgttcca atcactccga ttttcccacc
    41101 ttgactggac ttgatggctg ccgaagctcc tggcaaaatt acacccaaga caggaatatc
    41161 tagttgagcc ttgatttctt cccagacgac cgcagtcgca gtgttacaag caatgacaat
    41221 cattttgaca tccttggtca agagaaagtt gaccagctgc caagtatatt cacgaatttg
    41281 ctcagcagga cgggggccat agggcgcccg cgccgaatct ccaatataga cgatttcttc
    41341 atggggaagc tggcgcatga gctcgcgcac aacggtcaag cccccgacac ccgaatccaa
    41401 aaaaccaatt ggtcgattat ccatacagtc ttctttctag tcttttttct gattgatcgt
    41461 tcattatgat tccttgtact gaacgaactg accgacagct tgatagaatg tcaactacct
    41521 ctctcttaat cataatcaaa tatcaataga atgcaaggaa aaagtctcat ccctaaacca
    41581 taaccaacat agtgagaagt ctggaacttt catcccagac ttttccttat ttattttttc
    41641 tttttattgt tagcaagggc tgccttttgt tggcggatga tttggtggta aacttgttgt
    41701 accttagctt cgcttggttt ttgaccattt gcactcaaaa gagtacgaac tgcttcagca
    41761 ttcaaacgtg ggttgtcagc aaattctttt tcgatttgct tacgaaccaa gtacattcct
    41821 ccaagagctc ctcctagaaa agctagcaca atcaatacaa ttgctaaaag taaatccatc
    41881 atttttctcc tgtttctttt tgaatccctt tcattatacc acaaactagc caccctgacc
    41941 agtttgttct acactttcag ggatggaata gacagcaaaa agaaccctgc ttttctgaaa
    42001 aagaggtctc cttgctaagt ttatactcaa tgaaaatcaa agagcaaact aggaagctag
    42061 ccacaggttg ctcaaagcac cgctttgagg ttgcagataa aactgacacg gtttgaagag
    42121 attttcgaag agtattaatt tacataaata gccagtgttt gatagggttt gagtagaatt
    42181 ttctcagaca cttctgcatc ttcatagttt gatatcaaaa tctgtccatt ttggtagact
    42241 gctggcaagt cgatttccac ttctttagca taaaagttat tgagcactag taacttttga
    42301 tcctcaaact ggcgttcaaa agcgtagact tgtttgctat cttcaaaggc tggtttgtaa
    42361 cttccttctg aaatgattgg catttcctta cgcagtcgaa tcaagtcttg atagaaggtg
    42421 aaaatcggac cctggatttc attttctaca ttgatgtatt tataggattt accagctttc
    42481 aaccatggag tgcctgttga aaatcctgca ttttccgaag catcccactg catgggaatg
    42541 cgtgaattat cacgcgactt agcttgaata atctggaagg cttcttgctg actctttcct
    42601 tcttctaaga gcgtctgata ggcattaagc gattcgacat ccacataatc agccatagaa
    42661 tcatagtctg ggtcaatcat cccgatttct tcacccatat agatataagg tgtcccacgt
    42721 gacaggtgaa tgctagccgc tagcatggtg gctccttcct tgcggaagtt ttgaatatcg
    42781 acaaaacggt tcaaggcacg tggttgatcg tgattgttcc aaaagagggc actccaaccg
    42841 tctttatcac tcatttcctt accccaacta tggtaaagac tcttcaactc ttcaaaatca
    42901 aagggagcca aggtccactt ttgtccatcc ttatagtcca ccttgaggtg atgaaaatta
    42961 aaggtcatgg ataattcctg acgatcaggc gacgaataga ggacacagtt ttccatggtg
    43021 gtagaagaca tttccccaac tgtcataaag ctatcgtcag atccaaaagt ggcttggttc
    43081 atcatacgca aatagttatg aacgatgggt ttgtctgtat aagctggctt cccttcattt
    43141 tcaggacagt ccactgaaac ctcgtcctta ccgatcaaat tgatcacatc aaatcggaaa
    43201 cctttgatac ccttgtcgcg ccagaaatta acaaccttga aaagctcctt acggacattg
    43261 gaattgcgcc agttaaggtc agcctgggtc tcatcaaata ggtgaagata gtatttccca
    43321 gtatccccga aaggcgtcca tgcagaacca ccaaacttag actgccaatc tgttggttgg
    43381 tcttggatga agaaaaagtc ttgataatac ttatcaccag ctagggcttt ctgaaaccat
    43441 tcatgctctg tcgaacaatg attaagtacc atgtccagca taaagtcaat cttgtgctct
    43501 ttaccgacac acaccatttc ctcaaaatca gccatatcac caaaaagagg atccactgcc
    43561 atataatctg aaatatcgta accattatcc cgttgagggc ttggatagaa tggattgagc
    43621 cagaccatat ccacacctag tttggctaaa tagggaattt tttcgataat cccacggaaa
    43681 tccccaatac cgttttcagt ggtgtctttg taagattttg gatagatttg atagactact
    43741 tttcctttat caagtgtcat ctgtttctcc ttttctgata aaagggagga agcagtcttc
    43801 cgtccctatt tgtgctattt caattatact caatgaaaat caaagaacaa actaggaagc
    43861 tagccacagg ttgctcaaaa cactattttg aggttgcaga tagagctgac gtggtttgaa
    43921 gagattttcg aagagtatta gattcgtgta gcgaccatga gagatgctcc agcttggatc
    43981 gttgtcggat aagttccggg aatagtcgct gtataagcat cttggttggt gatgataaca
    44041 ggagtttctg tcaccagacc tgcagcctta atgacatcca tatcaaaacg aatcagttgc
    44101 tgaccaactg taacgtgatc tccttggact acaagacttt caaaaccttt gccatcaaga
    44161 cctactgtat ccataccgat gtggatgagc aattcaactc cctcgtcaga gacaatgccg
    44221 atggcatgct tggtagggaa aagaaccgtc actgtcccat taactggaga ggtcaactca
    44281 ccttggcttg gttcaatgac tagaccttgc cccatgacac ctgatgcaaa aataggatcc
    44341 gtcgcttgac tcaattcttt cacttggcca gttagtgggc tgataatttc taccgaagta
    44401 agttctactg gttcatggtt cacaaattct gcttcttctt gagcaacgaa ttctgcctgc
    44461 aagttcgtat cgccctctgt ttttgtaaag agaccagcct tgcggaagaa gaaagtcaag
    44521 agcattggaa caacaatcgc aactagcata gttcctgcaa atggcagcat gtattgaggt
    44581 tgaatagaga gaatacctgg caaaccaccg ataccaatag aagccgcagt tacattaaaa
    44641 gtaacggata acatgcctgc aagggctgaa ccagtcatcc cagcaacaaa tggataaata
    44701 tattttacgt taaccccaaa aagagctggt tctgtaacac cgagataggc tgaaatggtt
    44761 gcaggaagtg aaacctgagc ctcacgctca tcatggcgat gcatgaaata atagacaaac
    44821 acggctgagc cttgagcaat attagaaaga gcaatcattg gccatagggc agtgccacca
    44881 gcatccgcaa tcaattgtgt atcaatggca ttggtcatat ggtgcagacc tgtgatgaca
    44941 aatggagcgt agagggcacc aaaaattgca ccgaagagcc atttaactgg accagttaaa
    45001 cctgccaaga caactgatga aagtccttgt ccaattgtcc aaccgattgg tcccaaaaca
    45061 gtatgagcca aaatcaaggc tggaatcaat gacaagaaag gtacaaaaat catagaaatg
    45121 acttctggga tatgcttgcg ccagaagatt tcaagataag acagactcaa acctgcaagc
    45181 aaggctggga taacttgggc ttggtaaccg atacgattaa cagtaaaata gccaaaattc
    45241 caaacccagt ttgccgcgat atcagctgct ggcgttgaag caaccgcata ggcattgagc
    45301 aactgaggcg ataccaaaca gattccgaga acaattccca aaatttggct ggttcccatc
    45361 ttacgagaaa cagaccaagt aatccctact ggtaagaact ggaagatagc ttcaccaggc
    45421 aaccagagga agtgattgac acctgcccaa aactgagagg attctgtgat ggtcttgcca
    45481 tccaacatcg accaatggac accttccaag acattacgga aaccgaggat caatcctccg
    45541 actatcaagg ctggaataat cggagtaaaa atctccgcca gagtggtcat aacacgttgg
    45601 accacgtttt gattactctt agctgcagac ttggctgctt ctttggaaac accctcaata
    45661 cctgaaacgg ctgtaaaatc attataaaag atgggcacgt catttccaat gattacctga
    45721 aattgacctg catttgtaaa agttccttta acagctggaa ttgactcgat agctttaaca
    45781 ttagccttct tatcatctcc taaaacaaag cgcatccgtg tcgcacagtg ggtgacggca
    45841 gtcacatttt ctttgcctcc aattgcctga agcagatctt tggcttcttg ttcaaatttt
    45901 cccatttgat tctccttata cttgtcaaag caagtttgat ttgataagta tattgtaaac
    45961 gataccaaac ttgtctgcaa cttgtttggt ataaaaaggg tgtttttttg taaattttct
    46021 agcacttgta tggtaaaata gatacaggtg ttcattaaac tagactaaaa acctatttaa
    46081 gcaggcaaaa tgaagaaata ccaacaatta tttaagcaaa tccaagaaac cattcaaaac
    46141 gagacttacg ctgtcggaga tttccttcct agcgagcacg accttatgga gcaatatcaa
    46201 gtgagtcgtg ataccgtccg aaaggccctg tctctcctcc aagaggaagg attgatcaaa
    46261 aagataagag ggcaaggttc tcaagtcgtc aaagaagaaa ccgtcaattt ccctgtatcc
    46321 aacctaacca gctaccaaga actagttaaa gaacttggac tgcgctctaa aaccaacgtg
    46381 gtcagtctgg acaagattat tattgataaa aaatcctcac tgataaccgg tttcccagag
    46441 tttcggatgg tttggaaggt ggtccgccag cgtgtggtgg atgatctggt atccgttctg
    46501 gatacagact atctggatat ggaactaatt ccaaatctca ctcgccaaat tgctgagcag
    46561 tctatctatt cttatataga aaatggcctc aaactcctta ttgattatgc tcagaaggaa
    46621 atcaccattg accactcaag cgaccgagac aagattctca tggacattgg caaagaccct
    46681 tatgtcgttt cgattaaatc aaaagtctat ctccaagacg gacgccaatt tcagtttacc
    46741 gaaagtcgcc ataagttaga aaaatttaga tttgtagatt ttgcaaaacg caagaaataa
    46801 aagactgaga caccagatct cagccttttt cggctctata atatttgtag tgggtaaccc
    46861 ccctat
//
LOCUS       DAYYYC010000012        45062 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.012, whole genome shotgun sequence.
ACCESSION   DAYYYC010000012 DAYYYC010000000
VERSION     DAYYYC010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45062
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.012"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(76..3753)
                     /gene="rpoC"
                     /locus_tag="ACHBV5_000665"
     CDS             complement(76..3753)
                     /gene="rpoC"
                     /locus_tag="ACHBV5_000665"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFM9966507.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(3786..7397)
                     /gene="rpoB"
                     /locus_tag="ACHBV5_000666"
     CDS             complement(3786..7397)
                     /gene="rpoB"
                     /locus_tag="ACHBV5_000666"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFM9966508.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            7813..7883
                     /locus_tag="ACHBV5_000667"
     tRNA            7813..7883
                     /locus_tag="ACHBV5_000667"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7845..7847,aa:Cys,seq:gca)
     gene            complement(8081..9412)
                     /locus_tag="ACHBV5_000668"
     CDS             complement(8081..9412)
                     /locus_tag="ACHBV5_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFM9966509.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(9641..10465)
                     /gene="endA"
                     /locus_tag="ACHBV5_000669"
     CDS             complement(9641..10465)
                     /gene="endA"
                     /locus_tag="ACHBV5_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HFM9966510.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(10504..10692)
                     /locus_tag="ACHBV5_000670"
     CDS             complement(10504..10692)
                     /locus_tag="ACHBV5_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFM9966511.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(10685..11968)
                     /gene="murA"
                     /locus_tag="ACHBV5_000671"
     CDS             complement(10685..11968)
                     /gene="murA"
                     /locus_tag="ACHBV5_000671"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFM9966512.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(11992..12222)
                     /locus_tag="ACHBV5_000672"
     CDS             complement(11992..12222)
                     /locus_tag="ACHBV5_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFM9966513.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(12280..13317)
                     /locus_tag="ACHBV5_000673"
     CDS             complement(12280..13317)
                     /locus_tag="ACHBV5_000673"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFM9966514.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(13301..13789)
                     /gene="coaD"
                     /locus_tag="ACHBV5_000674"
     CDS             complement(13301..13789)
                     /gene="coaD"
                     /locus_tag="ACHBV5_000674"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFM9966515.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(13779..14318)
                     /gene="rsmD"
                     /locus_tag="ACHBV5_000675"
     CDS             complement(13779..14318)
                     /gene="rsmD"
                     /locus_tag="ACHBV5_000675"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFM9966516.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(14383..15375)
                     /gene="asnA"
                     /locus_tag="ACHBV5_000676"
     CDS             complement(14383..15375)
                     /gene="asnA"
                     /locus_tag="ACHBV5_000676"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HFM9966517.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTSKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(15487..16170)
                     /locus_tag="ACHBV5_000677"
     CDS             complement(15487..16170)
                     /locus_tag="ACHBV5_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFM9966518.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(16226..16966)
                     /locus_tag="ACHBV5_000678"
     CDS             complement(16226..16966)
                     /locus_tag="ACHBV5_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFM9966519.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            17000..17278
                     /locus_tag="ACHBV5_000679"
     CDS             17000..17278
                     /locus_tag="ACHBV5_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFM9966520.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            17356..18282
                     /gene="yidC"
                     /locus_tag="ACHBV5_000680"
     CDS             17356..18282
                     /gene="yidC"
                     /locus_tag="ACHBV5_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFM9966521.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVHEELAKNPSKASAFST
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(18357..19151)
                     /gene="pflA"
                     /locus_tag="ACHBV5_000681"
     CDS             complement(18357..19151)
                     /gene="pflA"
                     /locus_tag="ACHBV5_000681"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFM9966522.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(19277..20527)
                     /locus_tag="ACHBV5_000682"
     CDS             complement(19277..20527)
                     /locus_tag="ACHBV5_000682"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFM9966523.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(20594..21421)
                     /gene="purR"
                     /locus_tag="ACHBV5_000683"
     CDS             complement(20594..21421)
                     /gene="purR"
                     /locus_tag="ACHBV5_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFM9966524.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(21688..22629)
                     /locus_tag="ACHBV5_000684"
     CDS             complement(21688..22629)
                     /locus_tag="ACHBV5_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HFM9966525.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(22619..23875)
                     /gene="rmuC"
                     /locus_tag="ACHBV5_000685"
     CDS             complement(22619..23875)
                     /gene="rmuC"
                     /locus_tag="ACHBV5_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HFM9966526.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(23877..24539)
                     /locus_tag="ACHBV5_000686"
     CDS             complement(23877..24539)
                     /locus_tag="ACHBV5_000686"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFM9966527.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(24502..25158)
                     /gene="rpe"
                     /locus_tag="ACHBV5_000687"
     CDS             complement(24502..25158)
                     /gene="rpe"
                     /locus_tag="ACHBV5_000687"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFM9966528.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVANPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(25169..26047)
                     /gene="rsgA"
                     /locus_tag="ACHBV5_000688"
     CDS             complement(25169..26047)
                     /gene="rsgA"
                     /locus_tag="ACHBV5_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFM9966529.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFFNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETHKKVSKKIPK"
     gene            complement(26049..26921)
                     /gene="rsmA"
                     /locus_tag="ACHBV5_000689"
     CDS             complement(26049..26921)
                     /gene="rsmA"
                     /locus_tag="ACHBV5_000689"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFM9966530.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFACLADALKGQGL"
     gene            complement(27052..27360)
                     /locus_tag="ACHBV5_000690"
     CDS             complement(27052..27360)
                     /locus_tag="ACHBV5_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966531.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(27353..27994)
                     /locus_tag="ACHBV5_000691"
     CDS             complement(27353..27994)
                     /locus_tag="ACHBV5_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966532.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRMIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(27996..30026)
                     /locus_tag="ACHBV5_000692"
     CDS             complement(27996..30026)
                     /locus_tag="ACHBV5_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HFM9966533.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREKVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSI
                     LGLGILWYQGALFMATVQLVIIALLLYGLILAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQYSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(30295..31194)
                     /locus_tag="ACHBV5_000693"
     CDS             complement(30295..31194)
                     /locus_tag="ACHBV5_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM9966534.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(31266..31826)
                     /gene="rnmV"
                     /locus_tag="ACHBV5_000694"
     CDS             complement(31266..31826)
                     /gene="rnmV"
                     /locus_tag="ACHBV5_000694"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFM9966535.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMMVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSCKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(31826..32599)
                     /locus_tag="ACHBV5_000695"
     CDS             complement(31826..32599)
                     /locus_tag="ACHBV5_000695"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFM9966536.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(32904..33797)
                     /locus_tag="ACHBV5_000696"
     CDS             complement(32904..33797)
                     /locus_tag="ACHBV5_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall surface anchor protein"
                     /protein_id="HFM9966537.1"
                     /translation="MVAQDPKAQDSTKLTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(34081..34215)
                     /gene="rpmH"
                     /locus_tag="ACHBV5_000697"
     CDS             complement(34081..34215)
                     /gene="rpmH"
                     /locus_tag="ACHBV5_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFM9966538.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(34360..35574)
                     /locus_tag="ACHBV5_000698"
     CDS             complement(34360..35574)
                     /locus_tag="ACHBV5_000698"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFM9966539.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(35730..36024)
                     /locus_tag="ACHBV5_000699"
                     /pseudo
     CDS             complement(35730..36024)
                     /locus_tag="ACHBV5_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36186..36638
                     /locus_tag="ACHBV5_000700"
     CDS             36186..36638
                     /locus_tag="ACHBV5_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFM9966540.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(36673..38061)
                     /locus_tag="ACHBV5_000701"
     CDS             complement(36673..38061)
                     /locus_tag="ACHBV5_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFM9966541.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            38127..39089
                     /locus_tag="ACHBV5_000702"
     CDS             38127..39089
                     /locus_tag="ACHBV5_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFM9966542.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKNYMEG"
     gene            complement(39118..39276)
                     /locus_tag="ACHBV5_000703"
     CDS             complement(39118..39276)
                     /locus_tag="ACHBV5_000703"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966543.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVVDETDEVS
                     NHTYGKAT"
     gene            complement(39340..40350)
                     /gene="ccpA"
                     /locus_tag="ACHBV5_000704"
     CDS             complement(39340..40350)
                     /gene="ccpA"
                     /locus_tag="ACHBV5_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFM9966544.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(40775..41374)
                     /locus_tag="ACHBV5_000705"
     CDS             complement(40775..41374)
                     /locus_tag="ACHBV5_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFM9966545.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(41376..42473)
                     /locus_tag="ACHBV5_000706"
     CDS             complement(41376..42473)
                     /locus_tag="ACHBV5_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFM9966546.1"
                     /translation="MLERLKSIHYMFWVSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGIMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VEQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     EAMTSMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(42473..43210)
                     /locus_tag="ACHBV5_000707"
     CDS             complement(42473..43210)
                     /locus_tag="ACHBV5_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9966547.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GEPANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(43212..44096)
                     /locus_tag="ACHBV5_000708"
     CDS             complement(43212..44096)
                     /locus_tag="ACHBV5_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966548.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFILTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(44083..44277)
                     /locus_tag="ACHBV5_000709"
     CDS             complement(44083..44277)
                     /locus_tag="ACHBV5_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966549.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIHGALGFGFM
                     IFVVFPMGMEWLKGESHDGG"
     gene            complement(44274..44480)
                     /locus_tag="ACHBV5_000710"
     CDS             complement(44274..44480)
                     /locus_tag="ACHBV5_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966550.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        12879 a        10500 c         8552 g        13131 t
ORIGIN      
        1 accacatttc gtggaaaaat ggagaaagtt ttcagaagag agaatgagag aaccctcggg
       61 ttctctcatt ctctcttatt ctactgtttc ttccacagtt tcaacggcag tatccacaac
      121 tacttctgtt gtttcttcat ttccttcttc ctctactgga ggattaaggt attcttcttc
      181 gttgacagca tgtggttcaa ggttacggta acgggccata ccagtaccag ctgggatgat
      241 cttaccgatg ataacatttt ctttaagtcc aaggagatgg tctttcttac cacggatagc
      301 tgcgtcagta aggacacgag ttgtttcctg gaaggaagcc gctgacaaga aactgtttgt
      361 ttcaagtgag gctttggtaa ttcccataag gactgggcga cctgtcgctg gaactccacc
      421 tgcgataagg acatctttgt tggcatctgt aaagtcattg atatccatga gggtacccat
      481 gagaagatct gtatcacctg gatccatgac acggacttta cggatcattt gacgaaccat
      541 tacctcgatg tgtttgtcac cgatttctac cccttggcta cggtaaactt tttgtacttc
      601 accgagaagg tacgtttcaa ctgacaagac atcacgaact gcaaggagac gttttggttg
      661 gatagaacct tctgtcagag cagcaccacg cgctacttgg cccccaactt cgacacgcat
      721 acgagctgta aatggaacga catattcacc ttcgccagtt tcacccttaa caaagacttt
      781 cttggtacga gttgatgcat cttcttcgat agcagtaact tgtcctttaa cctctgtaat
      841 aaccgcttcc cctttaggat tgcgggcttc aaagatttct tggacacgag gaagaccctg
      901 agtgatatcg gtatttgagg caaccccacc tgtgtggaag gtacgcattg taagctgtgt
      961 accaggttcc ccgatagatt gggcagcgat tgtaccaact gcttcaccaa cttcaaccgc
     1021 atcaccagtc gccaagttga taccgtaaca gtgacggcag acaccgtgac gagtgttaca
     1081 tgtaaataca gaacggatag tcacttcttc cacaccagca ttgacaattt cacgcgcctt
     1141 gtcttctgta atcaattcat ttggaccaat aatcactgca ccagtttctg gatgtttaac
     1201 agttttctta gtgtaacgac cgttgagacg ctcttcgaga gactcgatca tctcttttcc
     1261 ttctgcgata gaacggatca agagaccacg gtcagttcca cagtcgtcct cacggatgat
     1321 aacgtcttgg gcaacgtcga ccaaacgacg agtcaagtaa cctgagtcgg ctgtcttaag
     1381 ggccgtatcg gtcatacctt tacgagcacc gtgagttgag aagaacattt ccaataccga
     1441 caaaccttcg cggaagtttg aaaggattgg caattccatg atacgtccat tcggagcagc
     1501 catcagacca cgcataccgg caagctgtga gaagtttgag atgttaccac gggctccaga
     1561 gtccatcatc ataacgattg ggttcttagg atcttgatta gcaatcaagc gtttctcaag
     1621 tttttcacgg gcagcacgcc attcagctgt aacagcattg taacgctcgt cgtctgtgat
     1681 cataccacga cggaattgtt tggtgatttg ttcgacacgt ttgtgtgatt cttcaatgat
     1741 ttcagccttg tcatcaacga ctgggatatc ggcaataccc actgtcaatc ctgcaagagt
     1801 tgagtggtgg taaccgaggt tcttcatgcg gtcaagtagg gcagaagttt ctgtcgtacg
     1861 gaaacgtttg aagatttcag cgatgatatt tccgaggttt ttcttcttga atggagggtt
     1921 gagctcaaga ttgctgatag cttccttgat agctccacca agtggcaaga agtatttagc
     1981 tggaacacct tctgtcaagt tggcattgtt tggttcttgc aagtatggta gcccctctgg
     2041 catgatatcg ttgaagagaa ttttaccaac tgttgtaagc aagaccttat gtctttgctc
     2101 ttctgtccaa ggcttgttga ggctgtctgt tgcgatacca acacgtgagt ggaggtgaac
     2161 ataaccattg cggtaagcca taaccgcttc gtcacggtct ttgaagacca ttccttcacc
     2221 ttcgcgacca gcttcttcca tggtcaagta gtagttaccc aaaaccatgt cctgagatgg
     2281 agtaactacc ggtttcccat ctttcgggtt caagatgtgc tcagcagcta gcatgaggat
     2341 acgagcttct gcttgtgctt cttctgaaag tggtacgtgg atggccattt ggtccccgtc
     2401 aaagtcagca ttgtaggctt cacagacaag tgggtgcaag cgaagagcct taccatcaat
     2461 taagactggc tcgaaggctt ggatacccaa acggtgaagg gtcggtgcgc ggttcaaaag
     2521 cactgggtgt tctttaatca cttcttcaag gatatcccag atacgctcat ctccgcgttc
     2581 caccaagcgt ttagctgctt tgacgttttg cacgatatca cgggcaacga tttcacgcat
     2641 gacaaatggt ttaaagagtt caatcgccat ttcacgtggc acaccacatt ggtacatctt
     2701 aagagttgga ccaacggcga taacggaacg tcctgagaag tcaacacgtt taccgagcaa
     2761 gttttgacgg aagcgtcctt gtttaccttt aagcatgtgg ctcaatgatt tcaatggacg
     2821 gctacctggt cctgtgattg gacgaccacg acgaccattg tcaatcaaag catcaactgc
     2881 ttcttgaagc atacgcttct cattttgaac gatgatacct ggtgcattta actcaagcaa
     2941 acgagccaaa cggttgttac ggttgataac acggcggtaa aggtcattca agtcagatga
     3001 ggcaaaacgg ccaccatcca actgcaacat tggacgaaga tctggtggga taaccggaag
     3061 gatgttaaga atcatccatt caggtttgtt tccagacttg taaaaggcat ccaaaacatc
     3121 caaacgacgg atggctttga cacgtttttg tccagtagct gttttcaatt cttctttgag
     3181 ttcagcaatt tctttttcaa gatctacttg cttcaaaagg tcttggatgg cttccgcacc
     3241 catcttggca acaaatgaac cataaccata ttcacgcaag cgctctcggt attcgcgctc
     3301 tgtcatgata gacttgtgct caagtggtgt atccttagga tcaatcacca cataagccgc
     3361 aaagtagata acttcctcga gggcacgagg gctcatatca agggtcaagc ccatacggct
     3421 tggaatcccc ttgaagtacc agatgtgaga tacaggagct ttcaattcga tatgtcccat
     3481 acgctcacga cgaactttcg tacgcgttac ttcaacccca cagcggtcac aaacaattcc
     3541 tctgtaacga atgcgtttgt acttaccaca agcacattcc cagtcttttg taggaccaaa
     3601 gatcacttca tcaaagagtc cttcacgttc tggtttcaag gtacgataat tgattgtttc
     3661 aggttttttg acttctccat aagaccatga acggacttta cttggagaag ctagggtgat
     3721 ttgcatactt ttaaaacgat ttacatcaac cactatttct tccctttcta ttctaagtga
     3781 actgcttatt cttgttcagc agcttcttct gttgcttccg cttttgttgc tttctcagct
     3841 tcttcagctt caaaggctgc tttagcctct tgggctgctt tttcgcgggc tttttcaagg
     3901 tcatctacgt ggatgacatc ttcgtccatt ccttcatcca agtcgcgaag ttccacttct
     3961 tggtcatctt cgtctaggac acgcatgtca agaccaagag attgcaattc tttgacaaga
     4021 actcggaagg attctggaac acctggtttt ggaattggtt tgccttttgt aatagcttca
     4081 taggctttca aacgtccgtt gatatcgtcc gacttgtaag tcaagatttc ttgaaggaca
     4141 tttgacgcac cgtaggcttc aagagcccaa acctccatct caccgaaacg ttgtccacca
     4201 aactgagctt tacctccgag tggttgttgg gtaacagttg agtaaggtcc gactgaacgc
     4261 gcgtgcaatt tatcgtcaac catgtggtgg agtttgatca tgtacatgac tccaacagaa
     4321 acacggttat caaatggttc acctgtacgt ccatcgtaaa ggattgtctt ggcatcgcta
     4381 tccatacctg cttctttaac agttgaccaa agatcttcag aacttgctcc atcaaagact
     4441 ggtgtcgcaa tgtgaatacc aagagtacga gctgccatac caaggtgaag ctccataacc
     4501 tgaccgatat tcatacgtga tggcacccca agtgggttca acatgatgtc gactggagtt
     4561 ccgtctggaa ggtaaggcat gtcttctaca ggaacgatac gagagacaac ccctttgttt
     4621 ccatgacgtc cggccatttt atctccgacc ttaatcttac gtttttgagc gatgtaaaca
     4681 cgaaccaaca tgttaacacc tgattgcaac tcatctccat ttacacgtgt aaagatctta
     4741 acatcacgaa cgacaccatc ggcaccgtgt ggtacacgaa gagaagtatc acgcacttca
     4801 cgagacttgt ctccaaagat agcgtgcaag agacgttctt cagctgaaag atctttctca
     4861 cccttaggtg ttactttacc tacaagaata tcaccttctt taacctcagc accaatacgg
     4921 ataatcccca tttcgtcaag gtctttgagg gcatcttcac caacgtttgg aatttcgcga
     4981 gtgatttctt caggcccaag ctttgtatcg cgcgtttctg attcgtattc ttcaaggtga
     5041 acagatgtgt agacatcgtc cttcaccaag cgttcgctca tgataacggc atcctcgaag
     5101 ttgtaacctt cccaagtcat gtaggcaacg attgggtttt gtccaagcgc catttctcca
     5161 ttttccatag aaggtccgtc agcgatgaaa tcgccttttt caacgacatc accaactttt
     5221 acgagagtgc gttggttgta agcagtacct gagtttgaac gacggaattt ttggatgtgg
     5281 taaacatcca atgaaccatc ttcacgacga acttctacct tgtcagcatc tgcgtaagta
     5341 actttaccat catactgagc aatcacagcc gcaccagaat cgtgggctgc ttggtattcc
     5401 ataccagtac caacgtaagg tgcctgagga ttaatcaatg gcacagcctg acgttgcata
     5461 ttggctccca tgagggcacg gttggagtca tcgttttcca agaaaggaat acatgctgtc
     5521 gcaacggcaa ctacctgttt tggtgaaacg tccatgtagt caacaatatt agctggatac
     5581 tcttggttga ccccttggtg acgtcccatg acaatcttct cagcaaaggt tccatcttca
     5641 ttcagacgag agttagcctg agctacagta tattcatctt cttcatcagc tgtcaaccaa
     5701 acaatttcgt tcgtgacaac acctgtttca cggtcaacct tacggtatgg tgtttgaaca
     5761 aaaccatatt tgttcaagtg tccgtaagat gacaagttat tgatcaaacc gatgttaggt
     5821 ccttcaggtg tttcgattgg acacatacga ccatagtgag tgtagtgcac gtcacgcact
     5881 tcatatccgg cacggtcacg agtcaaacca ccaggtccta aggctgacaa acggcgtttg
     5941 tgagacaact cagaaagcgg gttgtgttgg tccatgaact gtgacaactg tgatgaacca
     6001 aagaattctt taactgcagc tgttacagga cggatattga taatttgttg tggtgtcaag
     6061 acttcattgt cctgaacaga catacgttca cggacattac gttccatacg agaaagtccc
     6121 aaacgtactt ggttggcaag caattcacca accgcacgga tacgacgatt tccaaggtgg
     6181 tcgatatcat ctacacggcc aagtccttca gccaagttga ggaagtagct catctcagca
     6241 aggatatctg caggagtcac cgtacgaacc ttgtcatctg ggttagcatt accaatgatc
     6301 gttacgacgc gatctggatc agttggagca acaaccttga atttttgaag aacaacaggc
     6361 tcagtcacaa cggctgcatc gtttgggatg tagacaatct tgttcaagtc gccatccaaa
     6421 tggctttcaa tgctttcaat cacgctacga gtcataatcg taccagcttc taccaagatt
     6481 tctccagttt cagggtctac caatggctct gcaatggttt ggttgagcaa acgtgtttta
     6541 acattgagtt ttttattgat tttgtaacga ccaactgctg ccaagtcata gcgacgtggg
     6601 tcaaagaagc gagccacaag caagctacgt gagctttcag ctgtcttagg ctcacctgga
     6661 cgaaggcgtt cgtaaatttc tttcaaggct tcgtctgtac gagagtccat tggattcttg
     6721 tggatatctt tttcaacagt gttgcgaacc aattcgctgt caccaaagat atcaaagatt
     6781 tcatcatcac ctgagaaacc aagagcacga accaaggttg taaatggaat cttacgagta
     6841 cggtcgatac gagtgtaggt gatatctttt gagtcgcttt caagttccaa ccaagctcca
     6901 cggttaggga taacagttga accatagccc accttaccat ttttgtctac tttgtcgtta
     6961 aagtaaacac ctggtgagcg gaccaactga gaaacgataa tacgttcacc accattgatg
     7021 atgaaagtac ccatttctgt catgattggg aaatcaccaa agaaaacttc ttgggtcttg
     7081 atttcgcctg tttctttatt gatcaaacgg aaggttacaa aaattggtgc tgagtagcta
     7141 gcatcgtgga tacgagcttc ttctagcgtg tattttggtt ccttgatttc atatccaaca
     7201 aattccaact ccattgtgtc tgtgaagttt gaaattggca atacatcttc aaacacttcc
     7261 ttaagaccgt ggtctaggaa agctttgaat gagtcagttt gaatttcaat caaatttggt
     7321 aagtcaagaa cttctttgat tcttgaaaaa ctacgacggg tacgatgttt cccgtattga
     7381 acgtcatgtc ctgccaagat gattctcctt tgtaaataag ttccaagcct tgtcaatcag
     7441 gcttttctaa tcgtcatatg gttgtaaacc ccttatcacc gtgtcctctt gacgaatttt
     7501 cagaatcttt aagcctctgt tacaaatgct cataatcttg aaaaaaagca caaaaagagc
     7561 agctaaatct gactttttca gaagatttaa ctgctgtgag ccttgtctgg acaatatttc
     7621 agacaaaacc tacgacaaat gattacccat attataccct atttagctag atttttcaag
     7681 gggtttcagt aggtttttgg taaatttttt cccatagaaa acttggcatc acattcgaat
     7741 cacgctatgg tacaaaaaac tgaaaaaact attgactgaa aatcattttc aaggtataat
     7801 aataaacgtt aaggcggtat agccaagtgg taaggcacgg ctctgcaaaa gcttgatcgt
     7861 cggttcaaat ccgtctaccg ccttctataa cttgatttat caggtttcaa atgaacagaa
     7921 agcccaattt gaagggcttt tcttattttc cctcgaataa atacgtataa ctttaaaaac
     7981 ttttggagcg agtttgtggc agagttcttt ccatggcata attccctttt gaaatcaatt
     8041 gaaaaaagct tcgtcacgcc tggtgacaaa agcctctagt ttattctgtt tcttcttcta
     8101 tttcgacttc tgtgatttgg acttttacct tggtaacacg tccattcttc actttatcat
     8161 tggttaagat aaactgtttg ttttggctga ccaattcata gctgagtttc tcagtcgttg
     8221 gaatagttcc cactcctgtc aaataataac cagcgatggt atcaacgtca tcactttcca
     8281 gttcaacatc aaagtaatta ttgaaatcat tgagggtcat agttccttga acaatgtagg
     8341 tatcctcgcc aatctgatga acatctattg ctgctttgtc cgtttcatca tcaatttcac
     8401 caacaatttc ctctaagagg tcttccaaag tcaccaaacc agccatacca ccgtattcat
     8461 ccagcaagat tgccatttgt ctttgggtat ttcgcagttc ttttagcaag tcatccacaa
     8521 aaatagtttc aggtacaaaa agtggatctt gtaaaattct cttccaaaca atattgtcaa
     8581 aaccgtccac aaagcctgcc ttaaggagac tcttggtgtg aatgattcca attacattgt
     8641 ccttatcccc atcataaacc gggatacgag aataattttg ttttaaaata ctttggataa
     8701 tggcttgact atcatcctga atatccacca taaaggcatc cgttcgaggc accataacct
     8761 ctcgtgccat cagttcatcg agcgaaaaga caccttgtag catctcaatc tcatcagcat
     8821 ccaatgtttc ttcactattt gtcagcatat aggcaatttc atcacgggtc atcttttcat
     8881 ccgcatcatc gaatgacata ggagtcaaat ggctcaagaa attggtcgaa gcagctaaaa
     8941 gccaaacaaa aggactgact agttttccga tcccaatgat aatcggcgct gtacgaattg
     9001 ccaaggcatc ctttagatta agagcgattc tcttaggata taattcccca aaaacgatgg
     9061 aaatataggt caaaaatgcc aaggatagaa aagttgccac ggcttgtgct gtttcgccat
     9121 tcccaagcca agaggcaatc acacgtccta gagtattagt taaactcgcc cctgataaga
     9181 ttgtaatcag ggtgattcct acctgaatgg ttgataaaaa gtggttagga ttttctagta
     9241 ccttcagcag gcggatgtag cgtctgtctc cttcttccgc cttttgttca actcgggcac
     9301 gattaagaga aaccatggcc atttctgtgg ctgagaaaaa ggcatttaat accgtcaaga
     9361 taaacaataa aacaaattgt agcaacaaat tctgactact tgggtcttcc atagttcttc
     9421 tcctaaaata gtatcttatc ctttattata tcacaaaatt taatccaata catattattt
     9481 tttcttaccg taacttctca aagtaacttc catctctctc ccaaaactgg aagttagttt
     9541 tagaagttgc tattttttct tagtacctgt tctagccctg cttaaactag taaaaagaac
     9601 tcctacatcc ataagtgaca taggagttta ggcttatctt ttactgagtt acagttactt
     9661 ctccagttcg gtaatccagt tgaagtccct tttgaacatt gggaactaga acattgaatt
     9721 ccaattctcc atccgaagac ttggcttcaa tctgtgaagc tgagggaact aaatcctcgt
     9781 ttgaagcgta gtaaagggtt acacggtaac ggacacgctt gttttggtcc aaggctttac
     9841 gcaccttgct ttcatagtag ttttgaccag tcgaatactc ggcttgtgcc tgatttgccc
     9901 aggctgtctg aacagcaatg tttttaggat tgcttgttga ggcatcaaaa ccatccaaac
     9961 caccgattaa ggcatagcct aacaaatgac ctctatcgac tgcatgggta taagagccct
    10021 ttagattctt gacctgatgc caacctggag gagtccaaga agttgaacca ttcccagttt
    10081 ctttacgatt cttgtactga cgagtggcct tagacaagag ggcattagct acggttggaa
    10141 cagtttcctt gcccactgtc tttgttttat tgtcagcgta gggcttactt gaaaccttgg
    10201 catctagatt tgttttatta ccattgacga taaaagcacc tgagccattc cactccagac
    10261 tcccctttat ttgactcttg actgcgtctg ttaagacact ctctgccaat gcttgactag
    10321 gagcttcaga cgcttgtttt ttctgactaa gattggtttt gggactatta ggtgccgacg
    10381 gcatctgctt gatataatag ctccctgtag acaaaagcaa taacactagc agtccgatta
    10441 gtgtctgtct tgtttttttg ttcatatttc tccttatctt tagaaaaagg ctggttctcc
    10501 agcctaattt cctgtaaatt tatgaatcaa ttcctgccat tttgctggag acaggatagc
    10561 ccatggatct tgacccttgc ccaagattcc ataacctacc attaaaccga ttcctagagc
    10621 cagagtacct aaaatcagta ctatgatgac taaaagtaaa cgcttgacta cgtagcttga
    10681 tttcttattc atcttcatca cttgcctcaa tccgctgaat cttagcacct agctgcgcca
    10741 acttctcatg gaaaccgtag taacctctat ccaagtgaac caatttaccg accacagttt
    10801 ctccctgtgc taccaaacct gtcaaaatca aggctgcact ggcacgaagg tcagttgaaa
    10861 gaacttctgc tccctgcaaa ggctgtccac caacaatacg agctgtatca cggataatct
    10921 cagaatgcaa gcccatgcgg cgcatctctt ctaggtgttg gaaacgattt tcgaaaactg
    10981 tctccaccat ggttgattcg ccttttgcaa ctgtcatcaa ggctgtaaat tgagcctgca
    11041 tatctgttgg aaatcctggg tggggcaagg ttttcacatg aacagctttt agattttcta
    11101 gttgagaacg aacacgaatt ccttcgtctt cttcaattac ttcaacaccc atttcaagta
    11161 acttggcaat caagggacgg ttgtgctccc agacagcgtc tcgaatcaag acatcaccac
    11221 cagtcatggc agcagctacc ataaaggttc ctgcttcgat acggtcttgg actacattgt
    11281 gagtcgtacc atgaagtttc tcaacaccag taatggttat agtctctgta ccagcacctt
    11341 tgaccttggc tcccatttca ttaaggagaa tggctaagtc aacaatctca ggctcacgcg
    11401 cagcattctc aatcactgtc accccatcag ccagagtcgc tgccatcatc aagttctgcg
    11461 ttgcaccaac acttggaaag tccatataga tatgagcgcc atgcaagcgt tctgccttgg
    11521 cttcgatgta accagctgtc tgactaatct taacccccat agcttccaga cctttcaaat
    11581 gaagatcaat aggacggcta ccaatcgtac aaccacctgg catggatacc ttggcatgac
    11641 ccacacgggc aaggattggc cctaatacaa cgatggaggc gcgcatcttg ctgacatact
    11701 tgtaaggggc ttcctcagtg atgtcgccag tagcatccac cttgacaaga tgagcttcct
    11761 catcaaagtc aaccttggca ttcaaaccac caactacctg attcataata aagacatccg
    11821 acaaaatcgg aacattctgc aagacggtct ttccttcact tgctagaata gtcgctgcca
    11881 acaagggtaa gactgcattt tttgctccct cgatcgtcac gcttcctacc agacgattat
    11941 cgccaccttg aaccacaatt ttatccatac tcgtttcctt tactcttgat ttcataataa
    12001 tcctctaagc gcttcttgcc acaaatgata caggctaata aagaaagaac tcaggatgta
    12061 gcctatgaca atgctaaaaa aggctactaa taaacgaact tttcttgtat tatcatctgt
    12121 cacttttaaa accttctccc atctaacaag atcctttaaa aggtaaaaac tcacataaat
    12181 aaagaacata tgactactta gagtgaataa taattgaacc atttgactat tataccatct
    12241 tctctgtttg tgcgctagtt tggaaacttc actcaaaaat tagggattgt ttttcaagta
    12301 atcaatcgca tcttgtaggg ttttaacggg cacgattttc atatccgtct tgattgtttt
    12361 agccgcttct agggctgttt ggtagttgtt tttcgcgtcc ggatgcgcct tttgttcttc
    12421 ttcgctaaca gggttatcag gagcaaagaa aatagcagca cctgccctag ccgaagctac
    12481 aaccttctta tcaatgcctc caatgtctcc cacattacca tcgcggtcaa tggtacctgt
    12541 accggcaaca atacgaccat tacgaagatc tgggtgagct atttgagtat agatagctag
    12601 actaaacatg agaccagcac ttgggccgcc aataccagct gttgaaaagc taattgggac
    12661 attgctgatt acctctgtac gatcaatcaa gccgattcca attccatttt tgccattttc
    12721 caaggtgata atctttcctt ctgcagactt ggtttgccca tcctcttcat aggtgacctt
    12781 gacggaatcc cctaattttt gagaactgac gtaatcaatc aagtctttgg aactatcaaa
    12841 ggtctgatca ttgactgctg tgactgtatc agagatattg agaatccctt taaaggttga
    12901 attatccgtc acattcaaaa cataaactcc aaagtacttg agttcgatat ccttaccagc
    12961 tgtttttagt ccttgatact tggccatatt ttgcgatgtt tgcatgtaga attgattgat
    13021 tcgcataaat tcaacatcgg aagaaccacc tgtagtctcc tgagcactac gaatatctgt
    13081 aaaaggtgtc aaccaagcat aaatcatatg agctaaagtg gcatgttgaa caccaaccgt
    13141 aacgaattga taggcaccag cttccttatc ttctgtgtca tttactttaa ggacttggcg
    13201 aatatcttcc gaaccacctg gaacctctat ataataaggc aagggcacta caaatgccaa
    13261 gaaagtcaca atcaaggccg caatgacgta taagggccat ctaatctttt ttttcatttc
    13321 ttatttcctc caaaatactc tcgggaacat ggcaggcaat atcctgacca aacttcaaaa
    13381 gctctcgaac acctgatgaa ctgatataga gatgttcagg ccggctatgt aaataaatag
    13441 tctctatatc agaagacagc tgatgattgt agtaatcaaa actagcttca tattgcaaat
    13501 ccgccgcatt cctcaacccc cgtactagga aagtagcccc cagtcttttt gcaacatcga
    13561 ccaccaattc atcatgagaa gccacgactt caacattttc caaatgtccc aaagcctttt
    13621 ctagcccccg tttacgattt tcaagaggga gaaatccttg tttgtgggga ttaaaaaaaa
    13681 tacccacata aagcttatca aaaagtctgc tcgcccgttc aatgatatcc agatgcccat
    13741 ttgtcatcgg atcaaatgag cctgtgaata agccaatctt atctgacata gactgtcacc
    13801 ttactaattc cataaatctt ttccttccag atacccagac aggcaatctc ttctggaagt
    13861 tcaacggcct tatccgtctc gcacacaacc ataacatctt cagaaaaaag ctctctctta
    13921 gccatttttt caatatctgc tacgatttgt tccttggcat agggagggtc taagaaaacg
    13981 aggtcaaatt ccccagatac ctgttccaat gccctctctg catccatctt gaggagttga
    14041 aattttccaa cttccttggt catctggata ttttcagcca cgatggtctg agccttacgg
    14101 tctcgctcca ccaaaacagc actggacatg ccacgcgata ctgcttcgat agataaacca
    14161 ccactacctg cataaaggtc caagactcgt cccccttcaa agtagggacc aatcatgtta
    14221 aaaatggctc ccctaacctt atccgaagta ggtcttgttg tcttgccttc tagtgtcttg
    14281 aggggacgtc ccccatagat tcctgatacg attttcatac tgtttattat accaaattat
    14341 agacaaaaag agaaagaaaa ccgaaccttg cggttcgatt ctctacaaaa tattttcgta
    14401 agtatcgcgt acttcttgag gccaaacact tgtttgcact tctccgatgt gtctcttgcg
    14461 aagtaggaac atggccatac gagattgtcc aattcctcca ccgattgtca atgggaatag
    14521 gccattcaac aaagacttgt gccattccaa ttccaagcgg tcttcatcac ctgtaatttc
    14581 cacctgacgt ctaagagttt cttcatctac acgaattccc atagaagaca actcaaaggc
    14641 tccacctaaa gactcattcc agacaagaat atcaccattt agacccttgt agccattctc
    14701 agactcgctt gtccagtcat catagtctgg tgcacgtcca tcgtgcggtt taccatctgg
    14761 caactcgcca ccgataccaa tcaaaaagac ggctccaaat tctttacaaa tcgcattttc
    14821 acgttctttc gatgtcaagt ctggatagcg ttctaccaat tcttctgtat ggataaaggt
    14881 gatttgtttt ggcaagatag actcgatgtc atagcgagct tcaacagcta gctcagtcag
    14941 gcgaatagcc ttataaatct tctcaactgt ttcttttaga taaacgatgt tacgcttacc
    15001 atttgggata accttctccc agtcccactg gtcaacataa acagagtggg ttgcatccaa
    15061 ggaatcctca tctggacgaa gggctttcat gtggacaaag agaccctctc cttcaccaaa
    15121 gccaaaacga gccaaggtgt ggcgtttcca tttagcaagt gagtgcacca cttcataagt
    15181 agcatcaggg atttggagaa ccttgaccga tactggattt tccacaccag acaggttgtc
    15241 ctgcattccg tcaccgacct tactcaagat aggaccttga acttcgacaa cttctagctt
    15301 atctttcaaa tactgggtaa aagtgttttt gacaaaggaa atttcttctt gttgatggat
    15361 aaaacttttc ttcatagaca actcctcaaa aatttaataa acgtattata cacctatttc
    15421 caagaaaaga aaagagaaaa tttaaaaaaa atcagtgtca ctcaaaacac tgatttcata
    15481 gaccttttag tcattgcgac caaagatacg tagaatactt aggaaaagat tgataaaatc
    15541 aagatagatg ctgagagcca ttgacaccac ccagcctgtc gctacacgac cttgtgattg
    15601 ttcataggcg aggcgaatct tttggttatc ccaagcaatc aaccctgaaa aaaccaaaac
    15661 catggctaca ctaatcatat aatcaaagaa gccactagcc aagaaaatat tgactaccat
    15721 agcaatcagt aaaccaatga gagctgccat cattgctcga ccaatcccac tcaagtcttt
    15781 cttggtaaag ataccaactg ccgccatgac aaagaagaga agggcgctcg atacaaaggc
    15841 agataaaact gtacccggag tatagaaagc caccacaaaa ctaagggtaa agccgtttaa
    15901 aacggagtaa agtaaaaata ctggaagagc agctggacta tttcttgaag ccatgctact
    15961 ggcaacgaaa accaaagcca actccgcaaa agtagcaatg gtcaaccaga gacgcccctg
    16021 catcaacaag taaaccaact gagactgaaa gaccgtcaac ataaggcctg ataccaaagc
    16081 agatagtccg attcccagac caacaaaggc ataaacctta gcgtaaaatt gattgagacc
    16141 tgcacggtca tgtataatag tgtgattcat ccttttctcc ttttctgtga acatctttcc
    16201 ttgattataa caaaaaaagt taaaattagc ttaaatggaa gattaaaata ccggctgcaa
    16261 ctgcaacatt caaactctcg gcctgcccct tcatgctaat atggaccaac tggtctgcac
    16321 tttcagccat aaggggacta attccttgac cctcatttcc cataactagt acaaaatttt
    16381 ctatagaagg cagttctctg taatcaacag aatctttaga tagggttgtt gctagcactg
    16441 ggatagctac ctttttagtt tcgtcaagaa gcgctggact agtcatccgg taaatgggca
    16501 gatggaaatg actaccttgc atggaacgta gggttttgag actgtagatg tctgccgact
    16561 tatctgaaac aatcactcct gtaaaacctg ctgcatccgc agttcgaatg atagttccta
    16621 cattaccggg atcttgcaca tcttccaaaa acaagaactt gccctgactc aaatcagctt
    16681 gtcctacttc ttctttttga accaccgcca caattccctg tggagtctga gaatccgcca
    16741 aatctagcaa aatatcctct gaaatccaga cagtttgcgg aaaagcagct aactgatctc
    16801 gataattttc tagggcaaag attttctcaa tcgtcactcc agcttggaca gcttcttcaa
    16861 acaagtgcca gccttcaatc aaataggcag acttgcggta ttttttttgg tgtaatttct
    16921 tggcattttt taccacagaa ttggcttttg aggttataat agtcatagaa atattataac
    16981 acaatcaaag gggtttggta tgcaaaaggt tagaatgatt gcccaaggta gggtacaggg
    17041 agtcggcttt cgttggggtg tttacagctt ggcacttgaa attggtggca tcacaggtcg
    17101 agtatggaat aacgacgatg gcacagtgga aatcttagcc caagcagact catctgctat
    17161 catggcaaaa tttatccaag aaatccgaaa aggaccgaca cctttttcaa aagtaagcta
    17221 cttagatgtc aaactaagca actttcctcc ctactctgac tttaaaatcg caaattaggt
    17281 ctccagaact attgtatatt ttgtaaaaaa acagtagaat agaaaggtat aatttttaaa
    17341 gaaggaataa aaacagtgaa atctattaaa cgttttgcac tctcagctat gggagcggct
    17401 atgttgcttg tcttgactgg ttgtgtcaat gtcgataaaa ccacaggtca gccaacagga
    17461 tttatttgga ataccatcgg agcccctatg gctgaagcta tcaagtactt cgctactgat
    17521 aaaggtctag gctttggtgt cgctatcatc atcgtaacca ttatcgtgcg cttgattatc
    17581 ttgccacttg gtatctacca atcatggaag gcaacgcttc actctgaaaa gatgaacgcc
    17641 ctcaagcacg tccttgagcc acaccaaacg cgtctcaaag aagcgactac tcaagaagaa
    17701 aaactcgaag cccaacaagc tctctttgct gctcaaaaag agcacggtat cagcatgttt
    17761 ggcggtgtag gatgtttccc tatcctcctt caaatgcctt tcttctctgc tatctacttt
    17821 gctgcccaac atactgaagg ggttgctcaa gcaagctacc taggcattcc tctaggttct
    17881 ccaagtatga ttttggttgc ctgtgctggt gtcctttact atcttcaatc gctcctttca
    17941 cttcacggag tagaagatga aatgcaaaga gaacaaatca agaaaatgat ttacatgagc
    18001 ccactcatga tcgtcgtctt ctccctcttc tcaccagcta gtgtcacact ttactgggtt
    18061 gtcggtggtt tcatgatgat tctccagcaa tttatcgtca actatatcgt tcgtccaaaa
    18121 cttcgcaaaa aagtccatga agaactggca aagaacccat caaaagcaag tgctttctca
    18181 acaccaagtg gacgaaaaga cgttacccct gaacaaccaa ctgctattac aagcaagaaa
    18241 aaacacaaaa atcgcaacgc tggaaaacaa cgttcgagat aagaagaaaa aggcttagct
    18301 gatttgctaa gtctttttgc aagtcaaaag cccgatgttt ccatcaggct tcttttctat
    18361 ccatgtacac gtttcatata atcttgataa ctttcggtat ccatgagttt tttagcgttc
    18421 ttgacgcgat ctgctgttgg tggtttgact ccttcgaggg aatatggaat tccaagttca
    18481 cgccacttga actcacccat ggtgtgataa ggtagaattt caaacttatc aacatttttg
    18541 agggtcttga cgaacttacc aagttcaatc aagtcatcat ctctgtctgt caatcctgga
    18601 actagcacgt ggcgaatcca gacaggtttt ccaatatctg atagatactg ggcacaagcc
    18661 aagatatttt tattggtttg gctagtgaca atcttgtgct gttcttcgtt gatttccttg
    18721 atatccaaaa gaaccaagtc agtgacagcc atgagtttgt caaacttctc aaggtaacgc
    18781 ggtttattac ggaaaggaag agcacaggtg tccaaggtac agtggattcc ttgttcctta
    18841 gccttggtga agagagcaat caggaaatca atctgcaaga gagcttctcc tccactgact
    18901 gtaatcccac ccttatttcc ccagaaacca cggtagcgca aggcctctgt caagacatca
    18961 tctaccgtcc gttcacgtga cttattggac tccatagccc aagtgtctgg gttgtggcaa
    19021 tactggcaac gcatgtgaca gccctgcaaa aagacaataa agcgaatacc aggcccatct
    19081 actgacccaa agctttctgt cgaatgcacc atccctgtca cttgtccata atcaattgtt
    19141 tcttcagaca tatcgttacc ttccttgaaa acgttttata gttttattat atcacgactt
    19201 gaaggaaaaa caagattttt gcctattttt tagaaagcaa tctgtttttc aatttcattt
    19261 tcaatctatt atcagattat tcttcaaaat cgaagccata taaggttgca aaatagtcct
    19321 cagggcgctc tgcacggcgg atttgacggg ctttaccttc ttcggtatag aggatttccg
    19381 cagaacgtaa tttggcatta tactggtagc ccattgaaaa tccgtgggca cctgtatcat
    19441 gaattaccag caaatcaccg atttctgtat gaggcagttc gcgattgact gcaaatttat
    19501 cattgttttc acagagtgaa ccaaccacat ctaccgcttc agctggtcca tctggatggg
    19561 tcacgttgct aatatgatgg taagctccgt acatagctgg acgcatgagg ttgactgctg
    19621 aggcatctac acctagatag gtacggtagg tttccttctt atgagtgact cttgtgacta
    19681 gagcaccgtg aggtgccagc ataaaacgac ccaattcggt gaaaatcttg acctgaccaa
    19741 gacctgctga cgtaagaact tcttcataca ccttacgaac tccctcacca atcaaggcga
    19801 tatcgttcgg ctcctggtct ggacgataat taacaccaat accgccagaa agattgataa
    19861 agtctaacga aatgcccaac ttttccttga tttcaacagc cagttcaaag agctgacgag
    19921 ccaactctgg ataatagaga tgggtcacgg tattggacgc taggaaggag tgaagcccaa
    19981 aagtcttggc tcctttttcc ttcaagatag caaaggcttc aaagagctgg tccttggtca
    20041 tgccaaactt agcctcccca ggattgtcca taatgtctgt ccccagttca aaaacgcctc
    20101 caggattata acgacaagag atgatttctg gaatgcctgc tactctctcc agatgttcaa
    20161 tatcttcaaa ggcatccaag ttaatggtcg cacccaattc acgtgcatag gcgtattcct
    20221 tgtctggcgt gttgttggaa gagaacataa tctcagaacc cagaaagtcc agtttatggc
    20281 tcatcaaaag ctctacataa ctagagcagt ccacaccaca accttcttct tggagaattt
    20341 tcaaaatagc tggagttgga gtagccttaa ctgcaaaata ttccttaaag cccttgttcc
    20401 acgaaaaagc ttggttgaca gctcttgcct tctcacgaat ccccttctca tcatacaagt
    20461 gaaagggagt cgggaactcg gcaacaatcg cttctaactc ttctctattg ataaatggtg
    20521 ttttcataag cttccttcta ttctgtttgc aaagaaaggc tgggacaatc gttccaacct
    20581 ttagttctat ctcttattta tcttcgtcaa agatattgcc aacctcaaca tcgatggctt
    20641 ggttcttgac atcaatattg gttaccttca agagtgactt gtagtcaaac tgcttttcac
    20701 gttcttcttg ggcattgtcc gcaaagaccg ctacacctgc cagttctgag tcgaactcgc
    20761 gcaagagact aatcataccg ttgaccgttc cgccaccttt caagaagtca tccacaatca
    20821 agacacggct gcctgcctta agactacgtt ttgaaaggaa cattttctcg atacggtcac
    20881 cacttgaacc tgaaacatag ttgacgctaa cagttgaacc ttcggtaatt ttcaggtcac
    20941 ggcgcacaat gacaaaagag acattgagga cattggcaac tgcatttgca agtggcacac
    21001 ccttagttgc tacggtcata accgcgtcaa ttttttggtc cataaagctt ttggcaataa
    21061 tacgaccaat atttttcaag atggctggtg tgctaagcaa atcagacaga tagatataac
    21121 cacctggcaa gatacggtca ctttctgaca acttggtacg caagtcttca accatttcct
    21181 tagcatcctg actcgaaata gacggtgtga agatgacacc tccgccagcc ccagtcactg
    21241 tctggatatg accgatttca atttcctcaa aggcgcgttt gataatgacg atatcttctg
    21301 agatggatga tttagcagac tcatactttt cagcaaaagt attgagacta gttagtttat
    21361 aaggattatt aatcaaatag ttggaaatga caaccatccg atcacttctt cttaatttca
    21421 tttctatttc ctattccatt tttattcaaa aaatcaaaaa gcaaactaga aagctggtcg
    21481 ctggtggttc aaaacactgc tttgagattg tcgatagaac tgacaaaccc tgtaatatac
    21541 ctgcatatat acatacgaca aggcgatact accctagttt gaagagattt tcgaagagta
    21601 ttcatttttg tcttttactt attataccat attcacataa aaaaacgaac attcttatcc
    21661 taaaaaatgc tcatttttct taaattatta atctaaatct ggtttataga aggaacgatt
    21721 atccatagcg aagattttat tggacatctc tcctttatcc accaaagcca gagctgttga
    21781 catcatcatc atgcttgcat ccagattgtc aatcatatgg ataatctctg cctccataat
    21841 acgtggacgg actggacttc catattcaag caagccgtgg tgactgagga tgacatgacg
    21901 aagcaaaacg acttcttcct tggtatcgtc gatgccgagt tccataactg tcttggtaat
    21961 ttcgctatca atgagagcga tatgtccaag aagattgcct cgcactgtgt actctgtctg
    22021 gtctggcccc gtcaactcga tgaccttagc taagtcatgc aacataatcc ccgcatagag
    22081 caggctctta ttgagctgag gataaacttc gctaatagcg tctgccaaac gcaccatggt
    22141 cgccgtatga taggccaagc ccgtttcaaa ggcatggtgg ttggtcttgg cagctggata
    22201 ggagtagaat tccttatcat acttggtgta gagatttcgg acaatccgtt gccagacagg
    22261 attttcaatt ttgaaaatca tttgcgacat gtagtcacga atttccttga catcaactgg
    22321 tgacttgacc ttgaaatcag ctgggtcatt gggttcacca gcttgaggca ggcggagagt
    22381 aatttgattg acttgagggg tattgttata aacttctcgg cgtcctttca tgtggacaac
    22441 cttacctgcg gtaaaggcct caatgttatg aggttgggca tcccagagct tcccatcaat
    22501 ctcgccacta tcatcttgga aggtaaaggc taggtagttt ttcccagctc gagtttgcct
    22561 caggtcagct gatttgatta ggtaaaagcc ttcaaataac tcatcttttt tcatgtgact
    22621 aatcttcata ttcttcctca ttttcttgaa aatggagtag atcaagcgca ggctcacctt
    22681 ctgacaactc aatgtgacgg agcgtccgct cgatagctat ggtacgacgg tttaataatt
    22741 catcaatatt gccagaggca tgttggagat gtttttgtgc cttgaccaga ataccaccaa
    22801 acttgccaaa ctcggtcttg acactggcaa gagtcttgct gatatggtcg gcactctttt
    22861 ggatattaag ggtcttgaaa ccaactgata gggagttaag aagggctgat agggtacttg
    22921 gtcctgcaac aataatctgt tcttcccgtc tcaaatcatc aaagaagacc ggattgcgga
    22981 cgatttctga gtagagacct tctgtcggaa caaacaagat tccaaaattg gttgtccgag
    23041 gcggtgctat gtacttgctc ttgatatcct tggcaaagcg cttgacgctt gctaggagtg
    23101 acttacgaca gcgttcaatc tcatccttgt cacctgtctc ataggcttct tccaagcggt
    23161 aataatctgc cagtggaaac ttagagtcaa ttggaagata gacgtattct tggtcgcctt
    23221 gtccgggtaa cttgatggca tactccactc gttcactaga gttttcaacc gttgcgtatt
    23281 ctcgttcgta ctgggcaggt gtcatgatgt cttcaataat ttgccccagt tgcaattctc
    23341 ccagaatccc tcgcgtcttg gttccagaga gaaccttgtt aagagctccg acatcacggg
    23401 caactgtctg catttctcca agaccacgat tgacagactc cagttgttta gaaactgtct
    23461 caaaggaagc ctgtaagcgt gtctgcaagg tcttttctag tttttcctcg accgtctggc
    23521 gcatttgttc caaacgttgc tcatttgatt cctgcaaggc ttggagacgt tggtctgtct
    23581 tgtctctagt ttggaggaga ttatctgtca tttcttgacg gacttgggtc aggccttggt
    23641 gcaattcaat ccgcacttct tgcaaacggt cgctgacagc cacttccaaa tctttttggt
    23701 ctaactggct ggcttgtctg gcttggtcaa agcggtaatc caactggtct gacaaatgat
    23761 ctgcctgatc ctccaagctc ttacttaagt gtttctcctg cctatcctgc ctttgccaaa
    23821 tcagaaagag accagctagg ttggcaatta ataatagaat aagtaaactt tccatcctac
    23881 ctcctatcct tgctatgcag tacgaccaca taaccatctg ggcaagttac cgacacttcc
    23941 ctatctatat attcgttaga agcgtacact tttttaaaga aaaaattttc ctctgtcaac
    24001 tcatacttgg ctccaagaat agtcagctgg ctatcccgaa ctggcataaa ggctagatag
    24061 tcgtagtctg aacgaggttc tagctgactg gtcccttctg gacaataagt aatcaagttt
    24121 tgcccatcct caatttctat ttgatgcata tagggtgcca acttaggatt gctaggcaga
    24181 aagacattgg ccaacatatg gtcaatacgg ccacccaagg caccgaaaat agtaacctga
    24241 gcctgaggat tttgttcaaa gatggttaag agagccaatt ccaaatcggt atcatctttt
    24301 tctggtcgtg cttggacaaa atgctgggca cgtttttgaa tcacctgtcg ctcttcttcg
    24361 gtcacagaat caaaatcccc aactgctaga gcaagaggca agtcttcttc caagacccag
    24421 agcgagcctc gatccacccc aacaaaagca tcaaaatctg tccgataatg accgcggtct
    24481 ccgcctgcaa aaacggcaac cctagtccag ttgttttctg agagtttgta ctcgctcatt
    24541 gacatctccc ttaaagacat aggaacctgc tacaaaaacg gtcgcaccag cttctttagc
    24601 ttgggcaata gtttggtcat caatcccacc atccacttcg atttcaaagt tcaaaccttt
    24661 ttcctcacga agagcaacca actcacgaac cttatccatg gtttctggca gaaaggcttg
    24721 cccaccaaaa cctggattaa ccgtcatgac taaaacttgg tcaactagat gaaggacgtg
    24781 cttgatggct tcaactgatg tgccaggatt gataacgact gaaggcttaa ctccgagtga
    24841 acgaattttt tggagggcgc catgaatatg aggcgttgct tctacatgga tactgatgat
    24901 gtctgcacct gcgcgcgcaa agtcttccag atggtgttca ggattcgcca ccatcaagtg
    24961 acagtcaaag accatcttac tatgtggacg aagtgcttca accacaccgg caccaaaact
    25021 gatttgtggc acaaaatgac tgtccatgat atcgatatgg gcatattctg ccccagttgc
    25081 ttctagacgt ttgatttcac gttcaaagtt ggcataatct gctgccagaa ttgacggagc
    25141 aatcttgtat tgagacatag gtttctcctt attttggaat ttttttgctg acttttttat
    25201 gggtttctct acgattttca atttcactaa ggaattgcag gtaattgtca aaacggaagg
    25261 ttgcaataac accctcttca acagctggtt tgacggcaca agacggctca tgggtatggg
    25321 tacaagtacg aaacttacaa tctcggctga cagtagcaat ctctgggaaa gcctgattga
    25381 ggtcttcagc ccttgatact tcatagtcca gagatgaaaa gcctggtgtg tctgcgattt
    25441 tacccccatt gaggttgaaa aaactaacag ctcgagtagt atggcgccca cgacccagac
    25501 tgtctgagat ttctcctgtt tcaagattga ggtctggtgc gattttgttg agaagagttg
    25561 acttcccaac acctgtctgc cccataaaga ccgtaacctt gcctgttaac aaagacagga
    25621 gttcctcttt actggtcaca aagtcatagc cgatgtcacc ataggtctgc tggtaaaaat
    25681 ccagttctcc cctatcttcc aacaaatcca ttttggaaat atagacaatg ggatggatgc
    25741 ccttgtgctc caaaagaacc aagaaacgat ccagcaaatt gctgttaaaa tcaggttcct
    25801 tgacggacat gattactaca gcttgatcga tattgacaat aggcggacga accagactgt
    25861 ttttccgttc gtgaattttt aggatatagc cttctgaatt ttcctcggca gagaaatcta
    25921 cccagtcccc aacataaggg gtatggcctt ttttacggaa attcccacgc gcgcgtgttt
    25981 gataaacctg gccatcactc tccacatagt agaaacctgc caaggcttta atgatttgtc
    26041 cctgcatctt agagtccttg ccctttaagt gcgtctgcta gacaggcaaa ttctgccaag
    26101 ctgagagctt ccccacgcac acttggtgac aagcctgcct ggtccaaagc cttggtcagc
    26161 ttgtccttga cctcttcagt cttaccaaag taacctgtca agttattcca caaggtctta
    26221 cggcgatggg taaaactagc cttggaaacc ttaaagaaga agttctcatc ttccactgct
    26281 acagctggct ctggacggcg caccattttc aagatggctg aatccacatt tggcgctggc
    26341 acaaagaccg tacgaggcac gataaaggca accttggctg tcatgtaata ctgcacggcg
    26401 atagacaagc taccgtaagc cttggtgtta ggctgggctg aaatgcggtc cgctacttct
    26461 ttctgcatca tgaccacaaa ctcactaaaa ggaatcccac tctcaatcaa gtgcatgaga
    26521 ataggcgtcg tgatgtagta aggcaaatta gccactacct tgattggcag gttaggattt
    26581 ttaaaatttt ggatatgttg cgccaaatca accttgagaa tatcttcgtt aactacagtc
    26641 acattatcaa aatcacgcag ggtatctgcc aaaattggca ccaaacggtg gtcaatctca
    26701 aaagccatga cttgggctgc acgctcagcc agaaactccg tcaaggcacc aatacctggc
    26761 ccgatttcga tgacattgac ctggtcatca atttcagccg tatccacaat tttttgaagg
    26821 atattggtat ccgtcaggaa attttgcccg aaggactttt taaaggtaaa accgtgacgc
    26881 tccagcactg ccttggtcac gctataatct gcaattctca tctattctct tttctattat
    26941 ctgttactac tattgtaaca cattcccctt gtattttggg aatgaaaatc ataccaaaaa
    27001 actatctttc ctcatgaaga aagatagtct tggaaatctt taaaagtggc cttaacagtt
    27061 ctctcgaaac atgcgttcaa aaaaatcagc ttcttgataa cttcgatttt cgggtagggt
    27121 caaatccaca tcctcctcca catcatccac tgtcagttca accgtctgag gtaaattttt
    27181 caaacgataa tgcttttgcc tttgcccttc aatactagca aaatcaagca aatagccatg
    27241 tactcggatt tgaaccaaaa ggagatgatt ggtcatattt tccatgatga ggatatcttc
    27301 taaaccacct ctggcactag gataatcaga tactctgcga atacggattt tttcacacat
    27361 gagcaagttt cctcatatca atgatttcat cagccttatt ccagactagg ggattatggg
    27421 tcgcaatgat gatcattcga ttttcatctt tcaaatccac caagagattc ataacctcct
    27481 ctgaattttc aggatcaaga gctgctgttg gttcatctgc caaaatcaag ggtggatttt
    27541 tcaaaatagt cttagcaagg gcaactcgtt gggcctctcc cccagataaa gtataaattt
    27601 tttgttctaa atccaaatac cctagattaa ctttttctaa agcccccact tgcctttcca
    27661 aacgttctac ttttgagatt ttctgaccaa caaaacccaa atccaaattt tctttgattg
    27721 attggttttc taagaggcca aaattttgaa agagatagcc catctgatct cgaaaatact
    27781 cacgagtggg aatggttttt aaatctttcc cctgatagag aacccttcct ccatctatct
    27841 tttctagctt tcccaagata ttcagcagcg tcgtctttcc gcttccactc tttccgatta
    27901 aggcataaac cttgcccttc tccagcttga gattcaaacc agagaaaatc gcgcggtcat
    27961 taaatttctt ttccaatcct tgaatatcaa tcatcttatt ttcctttcaa tactgccatg
    28021 ctaccagctt cttctttttt gtcctgcctt actaaaatca agagggcgtt aagcgtaaac
    28081 aaagctacaa ctagagcgct aatcaaacca tctcttgtca aaatactaga taggactagg
    28141 ccaagcaaga gaactcctcc ttgcgccagt aaatacttgc catgaagctc atagattgtc
    28201 ataccagcaa gacgtttaat cataagctcc cgtctgaact gctcaaaata gagaagattc
    28261 atggaatcaa ataacaagat agccgtagac agggtcaaaa tcgtcccaat aaggagagag
    28321 taaaactcca cccgtttgtc atttagtacc ttggcaaaaa atagctggct ttttaccaag
    28381 taagaaacct tgtgatacag accttgctct tttagagctg tgatgctgtc tccatatcga
    28441 tctagtttca aggcactatt agccgtagtt ccccacaaca tccctgcaac aggtcttgtt
    28501 ccagtcgctt gcggcgttag aactacaata atcggatctt ttaggtactg gcgtgttgtc
    28561 ttgtacccat cattatagag gaaacgttcc tgtcctgttt ctgtaaaagc tagccttacc
    28621 tgtgggaagt agtgtttctg actcgtcact tctacacttt cagatgaaaa gttttgcagg
    28681 taatctgtaa acaatccttg gtagtaggca gactgctctc gcaagctctc aggcaagatc
    28741 agcccaaact ctccctcaga caagttttgc atcttgtcca taaactctga agaaacggta
    28801 atcttttctt ctatcagata gcgtggtgag acatagataa cattccctga cggtgtgtag
    28861 tcactgagac gattaccatc taggtccact tctgctccat ctgagaaatt gtcaacattg
    28921 ctcataatat aaaaagagtc tgtattggct aaccgttctt cagtaaatgt ctgccactca
    28981 cgattatcct tacgcgttcc ttcttcatcg gcaaatgcac tagaccaacc aaaggataga
    29041 cggtaacggt ctgagtactg gctccattta ttgctagctc tctccatttc ctgcatttca
    29101 cggtagtggg gtaggagagc tgtcgcactc gatccgacca ccaatacagc taagagttgc
    29161 cccaccatca tcaatgtcat catacgtttg agagggagtt tccctttcaa tagatccacc
    29221 agactatttt cctgtaaacc aagtagatag acgacactta gtaaggtaga aatccctgcc
    29281 aagatcaatc cataaagtag aagagcaatg atgaccagtt gcaccgttgc cataaacaag
    29341 gcaccttgat accagagaat ccccaatccc aaaatactgg ataccagcac tgagcagata
    29401 agctgtctca catcttctaa cactggtctg agagcaactc caaacaagct ctcaccagct
    29461 attaagcgaa tccctgcctg acgaagggat ttgatccgat aaatcagggt cagactcata
    29521 aaggtcagca gaaaaatagc taaactcagt agcaccatag gggtggccgt caatagtaag
    29581 actatcgaaa atggatcttc tccattcgaa acaaagcctt gatagccaag ttctttcaag
    29641 gtggtctgta agctcactcc atccaaactt cctgacacaa tcaagtaaga ccctaataaa
    29701 tcactcgttt ctgcactctc cttggaggaa atggtcagac cttctggaag ctctccctca
    29761 ccataagtgg cataggtaaa gagtgtttct ccagcttcat ttggctcaac gattcgacgg
    29821 gcgatgagac tattatgctc taccgccaag tgactcaaag cctctgtcac cttttcgcga
    29881 ctagctactg gttgatttat catcattcct gtcacatcaa cagaaggata gttaccaaat
    29941 aaaatctctt ctcgatggtc aacggaagtt atcaccatat aaagcgatac caataccatt
    30001 gaaatcaaaa taaataaacg tttcatcatt tcctccaaaa agttacttgg tcacttagtg
    30061 agaaggtgac cacagtcact gcgatgttaa gaagcttatt aagttctttc tgctagcaac
    30121 atcttcaaat atattatatc cgttttttca agaactatca aggacatcaa tgtccttaaa
    30181 atctaactat ttcatattat ttttagctta tatctaaaaa aacagttcta aagacgaact
    30241 ttagaactgt tttgatacga ggacaaggac atttttgtca ctgattcact atgtttataa
    30301 atattttttg acatcctctt gccattcctc tgtcaatttc tttactagaa atccatctcc
    30361 aattagcttc gcaaatgttt tagaagactg ataaaatgat tcagctaaac taaaatctct
    30421 ttctactctt aatgcttgct tccacaaaaa cataaataca agaggtttct tttgataatc
    30481 ttgagtttta tccataattt cttgtaaaca cgatagataa tcattaaaac aatcagttac
    30541 tcctaccttt tcaagacaac acattcctga aataagagta tctctaatta taaagtaatt
    30601 ctctatttga gttaccttct tctgttccaa aagaaagagc attagctttt cgatttgatt
    30661 tataaatttg gcaagatctt ttctaatgag catttgataa aaaaacaaac gaatcaacaa
    30721 catatcattt gttgaataaa cttctttttc tatgatctga gacatatgtt cctcaagtat
    30781 taactctgca tattcaggcc ttctagttct agaagtatcc aaacacgcct gcaatacttc
    30841 acatgctaat tgttcttctt taggaagatt atcaaagtat gttttataaa tctcttccaa
    30901 acacgcttcc ttcttatcgt actcctcttc tttaccatag attggttcac gtaaaatctg
    30961 gtatttcaat tctaaataag cagaaggaag agctgaaaaa tccggcataa ggctataaac
    31021 tggaactcct agccggcgag caatatagtc taacttgggc aaactcggtt gcgaagctcc
    31081 actttcaatt cgcgacagtt gacgaactgt cagttcttgc tcatctccac aaaaatctgg
    31141 acgactaatt cctttttcta tccgaatctc tttaattttt tgaccaatta acatcagacg
    31201 cctcctcttc tacctgcttc gaaaaatact gtgaaactta aaaaattgta acggtcacat
    31261 ctttcctact cataagattt catagcttct tccacttctg ccaaagtaac cccaaacaac
    31321 tctaggcgtt tgaggagttg cttgccgtta gaatagccga ttcggagagt ctctccgaga
    31381 tattctctac gcttacagct gtctgcccct gctagaaaac caaggcgaat caagtcgcta
    31441 cgactaatgt caaactgact ctcatgttca aattgttctg tcacctgagc tagagccgtt
    31501 ttcaggtctt catagctggc atgctcaatt cccagagaac gccccttggt cttggacttg
    31561 ggaacagctt catctcgctt gagaaaggca tgctgaactg ttggaatgac catcatgatc
    31621 atgcgccgaa tccgttcccc attaaaatct gggtctgtaa agacaatgac tccatgacgt
    31681 tggtgcaggc gctgaatccg ctctatatcc tgagcattga tggcagaacc tcgagtctca
    31741 taggtctcca catcgaaata acgtttgaga ttgaccgtat catcacgccc ttcaaccacg
    31801 ataacttgag aaattttctc tttcattact tgctgtccag tccaaaaatt cgttctgcat
    31861 ttgcagtcgt tgctaccgcc agctcttctg tcgtcatacc acgcaagtca gcgataaagt
    31921 cgaccacata gcgagtatag gctgttttat tttcacgacc acgcttgggt acaggtgcta
    31981 agtaaggcgc atctgtttcc accaacatct tgtccaaagg taactcttta gctgcttctt
    32041 ggaggtcagt tgccttctta aaagtcacca ctcctgagaa ggaaatggtc ataccaagat
    32101 ccacaaactt ctctgcccac tcaagcgtcc ctgaaaatga atgcatgata ccaccacgag
    32161 gaccaacgcc ctcactcttg ataatctcat aggtatcttc cagcgcatca cgggtatgga
    32221 caacaaaagg caaatccaag tccttagata gctgaatctg acggcgaaaa acctgctcct
    32281 gcacctcttt gggcgctgtc atccaatggt aatctaagcc aatttcacct aaagccacaa
    32341 ccttggaatg ttttaactta tccaacaagt aagcctcaac ttcctctgta taagtaccag
    32401 cttctgtagg atgccaacca atagtcgcat agagctgctc atactcatct accaactcca
    32461 aggcatgctc aatcgtcggt ttatcaaaac caacaatatt catctgtgtc acacccatct
    32521 cagcagccaa ggcaatttct tctgcctcac gacctgcaaa ttcttctaca ttcaagtgtg
    32581 tatgtgtatc aaaaatcatc tcttctaacc tcgttttcta tcttctatta taccaaaaaa
    32641 gaggaggggc acctaatttt tcggtttccc ctcctctctt caatagagag ctattctgct
    32701 atcttttcta tccgatattg cccatctcct attccacagt tagagacaga agagattggc
    32761 tacattgata gaatattcct attcagctaa agtatgtgat tatcttgggt tctcactttt
    32821 ctcacccatc actaggattg atgacttctc aaaatccccc ttataatcta actttaagta
    32881 gagaatagaa ttttctagct gttctatttt ctacgtctag tctttcttcc tagcaaagca
    32941 aaaccacttg ttgccaccac tagaccaaga ctagcaagtg ctgcacttga tgctgaacct
    33001 gtgttaggta attgtttgcc agcaggtgac tggtaggtaa catcttgcat tgttcctgca
    33061 gttgcttgcg gtgcacttgt tgtcttagga gcagcattag gagccactgg tctcttagga
    33121 actgtaacca tggcaatggc ttgcactcca atcgtttctg cttccttcac atcttccata
    33181 gttttcgcat tttcaatctc tttgagagct gcttgttttt ctgcttccac tcttgctaaa
    33241 agttctgctt tttctttatc agaaagcggt gcgcctttga tttcatcctg cttgtccttg
    33301 gctgcttttt caatggcatt tttagctgat tctttttcag tagctaattg cttagaagct
    33361 tgtgattgag ctgagttttg tgaacctgtg tgagctgatc cacccgcctg gctaccaccg
    33421 ccttcattcg cattagcatc tgagcttcca gtattgcctc ccttatctcc acctggtgta
    33481 ttttctagct tatactctgg tgtagcttct tgagttacag attcaccttt cgcagattgt
    33541 tgaactgtat cttttcctag aatcgtcact actgaaccat ctgggaatgt gattgttgct
    33601 gtaccatctc cagctacatt gattgtcgct ccgtctaatg ctgaaccatt tgcttgtaaa
    33661 atagcaacct taactttttc ttcatctgtt aaatgagtta tatcttttac atctactctt
    33721 tgagcaggtg ctttaacagt tgatttttca gcagtcagtt tagtgctatc ttgtgctttt
    33781 ggatcttgtg ctaccaattg atttcctgga attgtaatag ctgaaccatc tttaaagacg
    33841 attgttgctg taccatctcc acctacttca actttatagt aaaataaaat aataacagga
    33901 caaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaaacag aggtgtacta
    33961 ttctagtttc aatctactgt aacatcgctt ccgaatccgt ttgcatctac tgaacttttt
    34021 tacaaaaata aaaatcagta gactcgagtt cctactgatt tttgatagaa ttcgtttgga
    34081 ttatgcagcc aaaactttgc gtcctttacg acgacgagct gccaatacgc gacgaccatt
    34141 tttagttgac atacggttac ggaatccgtg tttgcgcgca cgacgaagtt tacttggttg
    34201 ataagtacgt ttcacgatga atacctcctc atagattttg tattcgttta gccggctata
    34261 aagtgatcag ttactaaaca tactttacta ttctatctga ttctttcact tttgtcaata
    34321 gctctaggca aatgtttcca gctttttcga atgcaagccc tatctacgat actgtttcaa
    34381 gaaacgagtc atcttttctt ggatttgggc taactcatca acacgaggaa ggtaaacgat
    34441 acggaagtgg tctggttcct gccagttaaa gcctcgacca tgaaccaaga gaaccttttc
    34501 ctgcttcaag aaatcaagga caaactgctc atcatcatcg atacggtaca tattgcggtc
    34561 gatttttggg aagatataga gccccgcctt gggtttaacg gcagacaaac ctggaatatc
    34621 ttgaatggca ttatagatga aatttctttg ctcgtagatt cgtccaccag gaagaagcaa
    34681 ttcatcgact gattggtgac cccccaagga agtttgtacg acttgttggg ccaaaacgtt
    34741 agagcaaagg cgcatattgg acagcatatt gagcccttcg atatagccct taacatgagt
    34801 cttagggcca gacaagacca tccaacccac acggaaacct gctatgcggt gggattttga
    34861 cagaccattc atgctgacac agaagacatc tggtgccaag ctcgccacag gcgtatgcac
    34921 atgtccgtcc attaccatgc ggtcatagat ttcatccgca aagataatca aatcgttttg
    34981 acgggcaatc tcaataatct ccagcaagag ttccttagga taaagggctc cagttgggtt
    35041 attgggattg ataaggacaa ttgccttggt attggaagtg atttttgact tgatatcgtc
    35101 aatatctggg taccattcca cagcttcatc acagatatag tgaacggcat ttcctccagc
    35161 taggctgaca gccgccgtcc atagaggata gtctggcatt ggcactaaga cctcatcccc
    35221 attgtccaaa agcccctgca tggacatgac aatcaactca ctgacaccat ttccaaggta
    35281 aatatcatca atatctacgt ttgggaattt cttcagctgg caatactgca tgatggcctt
    35341 acgggctgag aaaatccctt tggagtcaga atagccttca ctatcacgcg cattcataat
    35401 caagtcatga atgacctcgt ctggcgctgt aaagccaaat tctgctggat ttcctgtatt
    35461 cagacgtaaa atcttttctc cattcgctcg catccgcatg gcttcttcca atacaggacc
    35521 acggatatca taagcaacat gctctaactt actagacttg ttatattctt tcatcttgtt
    35581 tcctcaattc atcaggatag taacattata ccactagaaa gagaatgcga caagtttact
    35641 gaaatgtgtt actagtttcg tatagaagaa aaaccttgct aaaggcgagg ttaagaacgt
    35701 agagatagca ggtattttgc aaagacacat cacataccaa aagataaacc tagaaaaaag
    35761 caagcctaga aaggagtcat aaagaagatt aaacatgagg aaaagccccc atatcatcaa
    35821 gtaatcccaa cgcccacttc gttttgcaac tagaaataag attagatggt agagtacatg
    35881 aaaaactaaa aatccaataa aacttggata aagaagcggt accagactct ctaattgaca
    35941 gatcatgatc acttctacca agactgaaac taggataatt ccataataaa ggaaatttga
    36001 tttttgaaaa gagtttttca tcattctccc ttccttcact tctttcctgc tatcctttct
    36061 tttattttat catatattta tatagagttt aagccctaat attcttttga aaaatacttt
    36121 ttttgcttta cttctatagt gaaaaggttt acaattatag taagaaaatt tcaggaggtt
    36181 tcattatggc acaacgttac caaaatatca tggtcgcaat cgatggttct aaggaagcgg
    36241 acttggcttt tgtcaaggga gttcattctg ctctacgaaa cgacgctaaa ctcaccatcg
    36301 cacatgtcat tgacacacgc gctctccaaa gcgtatccac ctttgatgct gaagtttacg
    36361 aagaactcca agtcgacgct gaaagtctga tgaaagagta cgaaaaacgt gctaaagatg
    36421 ctggggtagc agatgttcat atcgtcattg aaatgggaaa tccaaagacc ctgctagcac
    36481 gtactattcc agatgccgag gaagtggacc tcatcctcgt tggcgcaact ggtctcaacg
    36541 cctttgaacg cctcttggtc ggctcttcat ctgaatacat actccgccat gctaaggtcg
    36601 atttgctggt tgtgagagaa caagaaaaaa ccttataatc acaaagaaaa ggagccccta
    36661 gctccttttt gtttacgatt tatttctctc tttatggcgt tcgtaagcct tgagctggcg
    36721 ctgcagttcc tttttaatag caggttctgg agcatatttt tcttcccaat tatctggttt
    36781 taagatttta tgggtcactg gatcaaaatg agccttgcca tctggaaaaa ttttccccat
    36841 attggcctga tggacaatat caaaaatacg ttctgggtcc acccccatca agacaaaact
    36901 gccgtaggtg aagtaaagcg tgtcaatcaa ggcatccact tgccctatca aatcttgctg
    36961 agcaggtgtc ttcttggcta ctttacctgc tgccttatca agggcctgat gaagttgcga
    37021 tacagcttga ccaaaatctt cttcagaagg actggctgat cgaacaaact ccaccaattc
    37081 ttctatttta aaaccagccc tatgggttgc accctctaaa tcccaagctc gaggttcttc
    37141 ttgggttcgt tcatccatca tgtggtggaa ggtcttgacc ttattgaaat gatagtcacg
    37201 gctgacaaaa actttttctg aagacaaaac accaaaatgt tccaaggcct tgtggatccc
    37261 atcttgttga ttgctagtgg taatgtgctt ggcagcttcc ttgacactgc tactaccatt
    37321 tcccatagcg accgacatac cgacgccagc cagcatttca aggtcattat ctgagtcacc
    37381 aaaagccatg acttggttga ggtcaaagcc atattctttc ccaactcggc gaatgccttc
    37441 taatttagaa tttccctgat tgatgacatc cgatgcaaaa ggattgctac gtgtcaattt
    37501 caagtcttca aaatcagctg ccgccttctc agattcttct ggtgtcatca gcatcaaaac
    37561 ttggtaaata ggttgattca tcaggtgaag caggtcctct tccttttggg gaacaacctt
    37621 gctgaccatg cgattaaaag actgactcac cgtccgagtt aaaacagagg gaacgaagcg
    37681 actaattcgt tgggaaaaag aacccagacc aaaggacatg attttagaac ccaacatggc
    37741 atccttggtc cctaaggcaa tctccgtgcc ctctttttta gcatagctaa ttagatggcg
    37801 caaatgtaac ttggaaatag ggctcgtgaa caagactctg tctttactaa agatatactg
    37861 gccattatag gttaccgcaa aatccagatc caaatcgtcc atcaattcct taacaaaaaa
    37921 aggtcctcgc cctgtcgcta cgccaactag taccccttgt tctttgacaa tcttaatcgc
    37981 gtccttagtg gatttcaaaa cactcttgcg attgttgacc aaggttccat cgatatcaaa
    38041 aaaaacagct ttgacttcca tcctatccca atctcccctt ttgtgataca atgattatac
    38101 cacatttcag aaagagtgag taaatcatgc ctaagaaaat ccttgtttta catacgggtg
    38161 gaactatttc catgcaggcc gatgcttctg gcgctgttgt gacgagttca gataatccca
    38221 tgaaccatgt gtccaaccca cttgaaggaa tccaagtcca cgccttggac ttttttaacc
    38281 ttccaagtcc ccatatcaaa cccaaacata tgctggtcct ctaccagaaa attaaagagg
    38341 aagcagataa ctacgatgga gtggtgatca cacacggaac cgatacttta gaggaaacag
    38401 cctatttcct tgataccatg gaagttcccc atatgcctat cgttctaaca ggagccatgc
    38461 gtagctccaa tgagctcggt agtgatggtg tttataatta cctaagtgct ttacgagtgg
    38521 ccagcgatga cagggctgct gacaaaggag ttttggtcgt tatgaacgat gaaatccacg
    38581 ctgccaagta tgtcaccaaa acacatacga ctaatgtcag caccttccag actccaacac
    38641 atggccccct cggtctcatc atgaaacagg aaatcctcta cttcaaaaca gctgaacctc
    38701 gtgttcgctt tgaccttgat cacatacaag gtttagtccc tatcatctcg gcttatgctg
    38761 gtatgacaga tgagctgatt gatatgctgg atttagaaca cttggacggt ttgattatcc
    38821 aagccttcgg agctggtaat attcccaaag aaacggctca aaaattagaa agccttctgc
    38881 aaaaaggaat tccagtcgct ctggtatcac gatgctttaa cggtattgcc gagcctgttt
    38941 atgcctacca gggtgggggc gtacagttgc aaaaagcagg cgttttcttt gttaaagaac
    39001 tcaacgccca aaaagctcgc ttgaaactcc tcatcgccct caatgccgga ctaacaggac
    39061 aggctttgaa aaactatatg gaaggctaat actcttcgaa aatctctgca aaccacgtca
    39121 cgtcgcctta ccgtatgtat ggttactgac ttcgtcagtt tcatctacaa cctcaaaaac
    39181 atgttttgag ctgacttcgt cagttctatc tacaacctca aaacagtgtg ttgcgcagcc
    39241 tttaaccagt cgcctagtcc gctctatggt attcattaag tcaacatctc ttgtttaaga
    39301 gcacaaaatc aggaaatctt ctcgattccc tgattttttc tatttacgtt ttcgtgttga
    39361 gctacgttct gtcaaaccat gaggtaagag aacttcacgt tcttccaact cttccttatg
    39421 cataatcttg gtcaacatac gcatactaat ggcaccaaga tcataaagag gttgggcaat
    39481 cgttgtcaag tttggacggg taaagcgtga gatttgtgaa tcatcactag taataatttc
    39541 aaaatcttct ggcacagaaa cacccttatc agccaaaccg ttcaagactc ctgctgccaa
    39601 ctcatcacct gtcacaactg ctgcagttgc atttgatgaa atcaaacgct ctgctaaggc
    39661 gtaaccatca tcatagctat atttagattc aaataccaaa ccctcactat aagtgattcc
    39721 tgcttttttc aaggtttcct tgtagccaac taaacgaacc ttaccattga tgtcatccac
    39781 tagcggaccg ctaacgaaag caatacgctc attttcttta gcaaggtaac tcactgcatc
    39841 aattgttgct tgcttatagt caatattgac acttggcaac tggtgctcaa catcgacagt
    39901 tcctgcgaga acaatcggag tacgtgaacg cgaaaattct gagcgaattt tatctgtcaa
    39961 gtgataaccc atatagataa tgccatctac ctgctttgaa aagagggtat tgacaacaga
    40021 aacttctttc tcgttatctt catcgctatt agctaggaca atattgtact tgtacatttc
    40081 tgcaatatca tcaatcccct tagccaaact cgaaaaataa ccattggtaa tatttggaat
    40141 cacgacaccg acagtggttg tctttttact tgcaagacca cgcgcaactg catttggacg
    40201 ataatccaaa cgatcaatta cctctagcac ttttttacgg gtattctctt ttacattttt
    40261 attgccattg accacacggc tgaccgtcgc catggaaaca cctgcttcac gagcgacatc
    40321 ataaatggtt actgtatcat ctgcattcat tccttttcct gtcctttcta tctcacacat
    40381 tcttttacaa gtagaggtac tgattgaagc tctatatcta cttacaaaag tgaagatgtg
    40441 aaaatttcgt tttcatattt ctacttattc cattctatca ctaattgtaa acactttcaa
    40501 gtgttttttg aagattgatt gaaaaaattt catagaaaac ctaggtttag ctccttgcta
    40561 ccaccttaga ctaaacacaa aggaggaaac taagccctcc taaagttata gtaaaatgaa
    40621 ataagaacag gataaatcga tcaggacagt caaatcgatt tctaacaatg ttttagaagt
    40681 agaggtgtac tattctagtt tcaatctact ataggtattg ttccattcac taccgtcaat
    40741 tttagcacat agccttcata aaaatattat atcatcataa ccaaccagat tcttttgcga
    40801 tattagctgc ctctgttcga ttaccagcat ccagttttga aagaatattg gtgacatagt
    40861 ttcgaatagt tccgtttgag aggtaaagct gatctgcgat ttcttggttg gataagcccc
    40921 gggcgattcc ctttaagaca gcaatctctt gttctgtcaa cggattggga cgggtcatca
    40981 ccacttccat caattcaggc gaatactcct tgcgtccttc gaggacggtg tgcaaggttt
    41041 gcatgaggtc tgcaatgctt cgttccttta atacataagc atccactcca gccttgaccg
    41101 cacgttcaaa atacccagca cgcttgaagg tcgtcaccac aaccaccttt gtttcaagcc
    41161 tttctgatcg tatccactcc aagacttcaa gacctgtctt aacaggcatt tctacgtcaa
    41221 ggatggcgat atctacagac tccttttcta atagttggat tgcttcttgc ccattcttgg
    41281 cttgaaggac agactccaca tctggttgaa gcgtgagcaa ttgacacatg gcatctcgca
    41341 acatactttg atcttctgcg actaatactt tcatcttagt ttctctcctt ataaggtagt
    41401 cgaacttgca cttccgttgg atgtttctga ctgattacac ttacttctcc tgaaaatgga
    41461 aaaacacgat ctcggactgt atggagctca tctcctttta gaaaagcaaa gccgcagcca
    41521 tcatcactta ctgttaaaat gagttccttc tctgtccgtt ctaattttaa gtaagcttta
    41581 gacgctttgg catgtttgat gatattggtc accaactcaa gcaaaatcat agaagtcatt
    41641 gcctccaatt cttgagtaag gctagcagta tctagttggt tatccgtttc cacctcaatt
    41701 ccagcaattt ctaacatctt tttcacagtc tctagttcgg atgtcaaagt tctagactta
    41761 agattttcca caatggttcg aacttcacgc atcgattctt tgctaatttg ctgtatttct
    41821 cttaattcct tttccacttg tggataagcc tgcatttgaa atagctgcaa ggctagatct
    41881 gtcttgacac taagcatagc aaaggtatgt cccagactat catgcaaatc ctgaccgata
    41941 cgattgcgct cattttctgc tagcaataga tttatctggg tattttgctc gacctgagct
    42001 tctttcaaat cctcgacaag gcgaattcga accgagccca aagtcatcaa atcgacaaaa
    42061 gtaagaatta caagcatata gactagaaac tcaacttcga ttctctgaaa aatcaaaagt
    42121 cgccccacaa caaggacttg agcaaggaga aatgtccata catgtaaaga ctttaaacta
    42181 cgtacgccaa aatgataaat taagagattg gaaaggaaaa agaaaaacca gatataattc
    42241 ccagcaacaa aggcggtatt cccagctaca tagaccagca tgatccccca gaaaagccaa
    42301 gataggcgct ggttcttagt tattaaaaca cccaaatacg tcactacaaa tagaatatca
    42361 accaataaat gccaagcagg aagctcccca atcactacag gtaggatggg aaaaagcata
    42421 aaaatcaaac tgacccaaaa catatagtgt atgcttttca gtctttcaag cattaagcat
    42481 tctccttatg accttgaagg taaatagtca aaccaaataa aactgctgaa aaaacaagta
    42541 aataaactgt ggctgataga ttgatgccac cctcgtttaa gaaggtcttg agcaactcca
    42601 tcaattgata ggtcgggaga cacttaccaa ctgcttgcat ccagtctgga aataaagaaa
    42661 tgggcatcca gagtccgcct aaaacagcca atcctagata aagaagattg cccacaacag
    42721 acatcagctg actagttggt aagagagtca aggtcaagcc aagtgctaca aaagcaatac
    42781 tccccacaat cagcaaaatc gcagctccaa cccattttac tagaggcatg tctacacctc
    42841 ttacaaaatg tccaactgta aaaacaacca gaattgagac caaataatca accagcatac
    42901 ttgttatctt tgatagataa tattctacca tatttacagg gctatgacgc aatgttttct
    42961 gccagttgtt catcttatcg gtatgtaaaa cagctggaaa tgagaggata gttgtcgaca
    43021 tcatggaaaa ggcagtcatg gagatgaggt aatcacgcat aaaattcgcg ggttcacctg
    43081 gtgtgtcctg atagatacca gaaaaaaata aatagaaagc cgtcggcatc cctaccgaca
    43141 atagataata gattaattgt cgtttggtca ataaaaattc tatcttacta agtgctatcc
    43201 atcgtttcat cttagttatc tcccttctgc gtctcttcaa agattgtatt caacaaacta
    43261 cgattattaa cttcgatttc ttgcatccta catcctgctt gggctaatag ttcccagaaa
    43321 gcatctgctt ctcgagtgac tacttgtaaa gaatcttgct ttagggtcca gttttcaacc
    43381 aaatttgact gctctacgac ttccttgtaa gctataggaa ggataaagtg cttttctatt
    43441 tcctcgctac gcatagctag aggcgtcgta tctcgaatca actctccctt atttaagagc
    43501 aaaatgcggt ctgcagtgtg ttccacttcc tcaatataat gggacgaata gagaatggtg
    43561 actccttgcg cttttaactc ctggacaatt tcccaaaaac gttgacgagt tgaggtatcc
    43621 atggacgcag taggctcatc taaaaaaaca atctttggtc gcccaattaa ggtcaagatg
    43681 aaagaaaaga gacgcttttg accgcctgat aatttttctg ccaactgttc tttttgttgc
    43741 ttgacaaact gcaatagttg atcaatttcc tgattgctca aaggatttgg atagatacgt
    43801 tgaaagaaag caatcaactc tttaactttt aatttctgaa cgattacatt ttcttgaggg
    43861 aggtaagccc tagtatagtc taacttagaa ctcgtcactg gtaaaccttg aatagatact
    43921 tgaccgcttg tgaccagttt atctccaagc aaacaatcta agagtgttgt ctttccggca
    43981 ccatttggac caattaaggc aacacattca ccatcgttga tttcaaagga gatgttccgc
    44041 aaaatttcct tgtcttttat tttcttactc aatttctcaa ctttaaccac cgtcatgaga
    44101 ctctcctttc aaccactcca ttcccatagg gaaaacgacg aaaatcataa atccaaaccc
    44161 caaagcacca tgaatgaatt ggcgaagcaa ggcttgatca aaccaatcag taaacatttc
    44221 cactaaccat accaagagtg acaggccgat aaagaaatag atgatccctc tcttcattcc
    44281 tcaaactcct ttttcacatc tctgactaat ttcaaacctt ctctaacaag ccaagacatg
    44341 attccaaagc cagcaaagac cttccaagga aaatggtaga aatcctcatc caatcccgaa
    44401 aacatgagat aggtcataac tcctgctact actaaactca ttgcaataat cattttattt
    44461 ctcatctctt cttcccccat ttcatactac aattatagtc ttttaaaatc agaggaggca
    44521 gaagcttctg tcactagaaa atatgacaaa tgtcataaaa aattctgttc aaaacaagca
    44581 agatacacta tacaataaaa cacaatcaga aaaatctaag gcaacttcct caaaagagat
    44641 atcaaactca attcacacca taatgtaaac taatacttat ttaaaatcaa aaagagtaga
    44701 aatttttatc agacaaacac atatatagtg tattgaatct ataacagtag gccttaaata
    44761 ctaaaatatt tctataaatt aatttaactt tcctgataga actgttcata tcttatttca
    44821 attctctata ttatacgttg aacaaaaccc ttctattgct ttcttaaaaa tttataagag
    44881 ttataaaatc tgttaaattt caatgtgtat acctaaacta cggtatttat tgaaaagact
    44941 ggggacaaaa agtatacgct gccaaaatga attactgaaa atcaaaaaag agaggaccaa
    45001 actgattccc tcttaatgta tataatatct agttttaaaa atacacactc acatatctct
    45061 gt
//
LOCUS       DAYYYC010000013        40886 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.013, whole genome shotgun sequence.
ACCESSION   DAYYYC010000013 DAYYYC010000000
VERSION     DAYYYC010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40886
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.013"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            491..1009
                     /locus_tag="ACHBV5_000711"
     CDS             491..1009
                     /locus_tag="ACHBV5_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFM9966551.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            1139..1645
                     /locus_tag="ACHBV5_000712"
     CDS             1139..1645
                     /locus_tag="ACHBV5_000712"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFM9966552.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            1645..1815
                     /locus_tag="ACHBV5_000713"
     CDS             1645..1815
                     /locus_tag="ACHBV5_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966553.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            1847..3079
                     /gene="clpX"
                     /locus_tag="ACHBV5_000714"
     CDS             1847..3079
                     /gene="clpX"
                     /locus_tag="ACHBV5_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFM9966554.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIVFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            3088..3675
                     /gene="yihA"
                     /locus_tag="ACHBV5_000715"
     CDS             3088..3675
                     /gene="yihA"
                     /locus_tag="ACHBV5_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFM9966555.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            3686..4066
                     /locus_tag="ACHBV5_000716"
     CDS             3686..4066
                     /locus_tag="ACHBV5_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HFM9966556.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            4118..5008
                     /gene="rapZ"
                     /locus_tag="ACHBV5_000717"
     CDS             4118..5008
                     /gene="rapZ"
                     /locus_tag="ACHBV5_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFM9966557.1"
                     /translation="MTKKQFHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            5005..5982
                     /locus_tag="ACHBV5_000718"
     CDS             5005..5982
                     /locus_tag="ACHBV5_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HFM9966558.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            5979..6890
                     /gene="whiA"
                     /locus_tag="ACHBV5_000719"
     CDS             5979..6890
                     /gene="whiA"
                     /locus_tag="ACHBV5_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFM9966559.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(6978..8105)
                     /locus_tag="ACHBV5_000720"
     CDS             complement(6978..8105)
                     /locus_tag="ACHBV5_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM9966560.1"
                     /translation="MWMEELPNGKFKYFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESD
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(8384..9334)
                     /locus_tag="ACHBV5_000721"
     CDS             complement(8384..9334)
                     /locus_tag="ACHBV5_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HFM9966561.1"
                     /translation="MKPFKTIEEQIATLKIRGLSITDESKAAKYLLSNNYYNIINGYS
                     KFFQHPGTDTYIDGVTFDEVSSLYTFDKDVKRAILQAILEAEHHIKSITAHRFAEAYP
                     SQKYAYLNTNSYADNKILDVGFIVSKLSKIINTNKRYRGNSIHHYAHTHSDVPIWVLT
                     DYLEFGDLRTIIENLPNSLQNEIARDLVSFISTNIPDFNDVFPPETLISFLKNINEVR
                     NKCAHNNRLLNFRCRSNSTFWETIHNKEILMGDDSRKTVYSTIISLQCFISKAAFNIL
                     WNTLRKKVIKLEKKLPSIDINVINQSLGFPNDWHRNEPKV"
     gene            complement(9483..10274)
                     /locus_tag="ACHBV5_000722"
     CDS             complement(9483..10274)
                     /locus_tag="ACHBV5_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HFM9966562.1"
                     /translation="MDEKKRMQIIAENITHFRKQRGITQKELAKEVGITASTMTDYMK
                     LRSAPSFGVIQKLADYFGVKKSDIDTTFKEESTNSLPDAPDSLTQQIMDKVVQLTPPN
                     QKIVLRTSEELLESQNEEETKINEVSEVISLYQVEVVSETAAASGFNYGFGYDDTDRE
                     TIEVDERPPRHDIATKVSGDSMQPDYQDGDILYLVDKGLTTYNGDLAIIAYGDRSYFK
                     KIYTENGRLRLVSLNDKYEDIILDFPPAEDTHIKIYAVVGVYRGE"
     gene            complement(10518..11207)
                     /locus_tag="ACHBV5_000723"
     CDS             complement(10518..11207)
                     /locus_tag="ACHBV5_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HFM9966563.1"
                     /translation="MIFRVKVNSSVSRPVTVEDICPNCKKPTNPDLVNSSYFSLGENK
                     TSLVLTCRCLGCKHFWTEEFIATRFLINDYTEKYEIEHIKVIPNLPSDIPISDDVEIV
                     SPIGKQIYVQALKAEHEQLDHIAGIGYRKALEFFVKDFSIVTNPDDEDKIIKMSLKQV
                     IEKYIKDEDLKTFALASAYIGNDEGHYYRNNPDKGFTDLKNYLHGVIHYMEMKLNFLD
                     AQELVNRSKKS"
     gene            11414..11578
                     /locus_tag="ACHBV5_000724"
     CDS             11414..11578
                     /locus_tag="ACHBV5_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966564.1"
                     /translation="MKENIEHLHERIKHFQSLIAYMSEHEKKYYLEKDWFDNPTLISI
                     EDAKKEVELL"
     gene            11597..11812
                     /locus_tag="ACHBV5_000725"
     CDS             11597..11812
                     /locus_tag="ACHBV5_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001198773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM9966565.1"
                     /translation="MQWTLEAMRINKGLTQAELAEKFEVSSQTIARLEKDSSDIGYQL
                     LKKYMFFFNVKFDDIFLGKKYENFVNN"
     gene            11844..12044
                     /locus_tag="ACHBV5_000726"
     CDS             11844..12044
                     /locus_tag="ACHBV5_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966566.1"
                     /translation="MESVLESLKQEKDHLEKIIKVVTSGGKFLRLPYQKKSRSISENL
                     KLISQNLDKLSEQVQQTTNQHS"
     gene            complement(12443..12634)
                     /locus_tag="ACHBV5_000727"
     CDS             complement(12443..12634)
                     /locus_tag="ACHBV5_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966567.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTIELLEKYHEWLHS"
     gene            12753..12896
                     /locus_tag="ACHBV5_000728"
     CDS             12753..12896
                     /locus_tag="ACHBV5_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966568.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     RTV"
     gene            12893..13063
                     /locus_tag="ACHBV5_000729"
     CDS             12893..13063
                     /locus_tag="ACHBV5_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966569.1"
                     /translation="MKEAVKEFLKFRSRFTKIEWFEINQAVEARLNQKADQLKLDDVD
                     LEIISSRLEKVI"
     gene            complement(13056..13295)
                     /locus_tag="ACHBV5_000730"
     CDS             complement(13056..13295)
                     /locus_tag="ACHBV5_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966570.1"
                     /translation="MTEIHACLCGNWVNLSADDDCVMGPNMASPYIWWEENAELYSPI
                     SKPEANSMYHQDYIYIHYRGADYRIHPMFIQIVSR"
     gene            13413..13685
                     /locus_tag="ACHBV5_000731"
     CDS             13413..13685
                     /locus_tag="ACHBV5_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966571.1"
                     /translation="MEAVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            13682..13897
                     /locus_tag="ACHBV5_000732"
     CDS             13682..13897
                     /locus_tag="ACHBV5_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966572.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEKRWNIFTW"
     gene            13876..14064
                     /locus_tag="ACHBV5_000733"
     CDS             13876..14064
                     /locus_tag="ACHBV5_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966573.1"
                     /translation="MEYIYLVTIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMNL
                     RNSDKQFTYDVEPPEGLK"
     gene            14076..14417
                     /locus_tag="ACHBV5_000734"
     CDS             14076..14417
                     /locus_tag="ACHBV5_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966574.1"
                     /translation="MTQAERIREYYREHPAASYDEVAEVVGTTNSNVRANLAKDIKAG
                     RCVRLEDKSYDYSPYYNHTQALTELVDWKNDNRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            14418..14648
                     /locus_tag="ACHBV5_000735"
     CDS             14418..14648
                     /locus_tag="ACHBV5_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966575.1"
                     /translation="MVRNKIGDLTNTLFAQLETLDDRDLTADELKVELHRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            14662..15384
                     /locus_tag="ACHBV5_000736"
     CDS             14662..15384
                     /locus_tag="ACHBV5_000736"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFM9966576.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTNYNKSQIGGVRKRLGLAVGKV
                     YQGRLLTKEQHDYLVLIQKNKISRNVANEMNQKFGLSLTEKQIKSYRRNNNLHSGLTG
                     RFEKGQTPHNKGKKYPNMPKNGGQFKKGNRPPNYVPVGTINYTTNGYPKEKIGEPNQW
                     VLKHRKVWEDHHGLIPKGYSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            15377..15859
                     /locus_tag="ACHBV5_000737"
     CDS             15377..15859
                     /locus_tag="ACHBV5_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HFM9966577.1"
                     /translation="MASLYELTGQFLTIYQLDIDDETKADTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELVRTEKLVIK
                     "
     gene            15859..16218
                     /locus_tag="ACHBV5_000738"
     CDS             15859..16218
                     /locus_tag="ACHBV5_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966578.1"
                     /translation="MELMNKTRVTDSLAVVIGPESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            16218..16703
                     /locus_tag="ACHBV5_000739"
     CDS             16218..16703
                     /locus_tag="ACHBV5_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966579.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            16666..17859
                     /locus_tag="ACHBV5_000740"
     CDS             16666..17859
                     /locus_tag="ACHBV5_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFM9966580.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YQKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            17877..18194
                     /locus_tag="ACHBV5_000741"
     CDS             17877..18194
                     /locus_tag="ACHBV5_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966581.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            18194..19021
                     /locus_tag="ACHBV5_000742"
     CDS             18194..19021
                     /locus_tag="ACHBV5_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFM9966582.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYADQ
                     VDDKAILKILATIRGAVEPAKGKLAPKKEAAKTTKPAKTEKTKEAPKKEVDSDDELF"
     gene            19041..19547
                     /locus_tag="ACHBV5_000743"
     CDS             19041..19547
                     /locus_tag="ACHBV5_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966583.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALQRKAVGSYYNLVISVTKGKDGREFRNYDLEEEEAQPLTEAD
                     IDEDDLPF"
     gene            19720..20541
                     /locus_tag="ACHBV5_000744"
     CDS             19720..20541
                     /locus_tag="ACHBV5_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HFM9966584.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLIEFADKPAMTPSEIE
                     NFWDGYPNANIALKTTNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKYLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPTPLPEKEMMRTIESMIKKDRR"
     gene            20544..21887
                     /locus_tag="ACHBV5_000745"
     CDS             20544..21887
                     /locus_tag="ACHBV5_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HFM9966585.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSSQAMLDGMET
                     FFSERSYNPVIEYMEKAAEKWDGRKRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQTEYLKDKTGER
                     RFLPVMADSKRQKKHPMEIEPETIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKTNR"
     gene            22180..22335
                     /locus_tag="ACHBV5_000746"
     CDS             22180..22335
                     /locus_tag="ACHBV5_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966586.1"
                     /translation="MSYTVTLFFDNMVDETHFFKKESDAAKCKAQLESKYRGNRMYKV
                     KQEKLEE"
     gene            22332..23027
                     /locus_tag="ACHBV5_000747"
     CDS             22332..23027
                     /locus_tag="ACHBV5_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HFM9966587.1"
                     /translation="MNKQELIKRIEDLPYTEGPIADTIEINRNWILKSIEQLAESEIG
                     HADEAPRYVKNILARLRELPLHDREFWLKAIMSEFEQDFSHAKWREGYEQGKIEGMVE
                     REKVIVPQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLDG
                     YEVEKEKRYFVKIKGNIKENMLVYGELLKRYFFTKSFSLDDVIYSHTRKELENAKIGW
                     VFDCEGFEIEEVE"
     gene            23027..23188
                     /locus_tag="ACHBV5_000748"
     CDS             23027..23188
                     /locus_tag="ACHBV5_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966588.1"
                     /translation="MSLTLNSTIGDLVLAIGEIIVGSDGKTTTAILEIPDQSFYLEIE
                     LKLKEEVIN"
     gene            23185..23445
                     /locus_tag="ACHBV5_000749"
     CDS             23185..23445
                     /locus_tag="ACHBV5_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HFM9966589.1"
                     /translation="MKRFIAIWILLSAGLNIWQSIYIKKLEEKRPIVVYKADNAGAEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYEKVKVGDEVLL"
     gene            23445..23903
                     /locus_tag="ACHBV5_000750"
     CDS             23445..23903
                     /locus_tag="ACHBV5_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966590.1"
                     /translation="MDDILQALAKMLNMTVDEVSSLLTTFKGNAPQIYEMFVKEKMFY
                     DLFSLFQIMSIVIFSISAVVLAVLTLIYFTYDGGFVYSYDIRTGKTEEEIKLERIERK
                     RKDLKIPLKISCISSSASLITLVIAIVLKATLAPNYIFIVNEILPKLTKR"
     gene            24016..24453
                     /locus_tag="ACHBV5_000751"
     CDS             24016..24453
                     /locus_tag="ACHBV5_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFM9966591.1"
                     /translation="MIPKFRVWVKIGKRMVFSDDILAIDYENKEIVTQQVYFENGLPD
                     DRDIYCYDFDEIELMQSTGLKDKNGKEIFEGDIVRTTRFLGRADEIGGFYEYDKEFIG
                     IVKQLEGSWVIDTGSDAVCLWTEIEENEIIGNIYENKEFGGRK"
     gene            24450..24821
                     /locus_tag="ACHBV5_000752"
     CDS             24450..24821
                     /locus_tag="ACHBV5_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966592.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFDEVPIVEEVKVEFGVE
                     ASMGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRF
                     LTFRESDWKFFIRDLVNEFKH"
     gene            24894..25298
                     /locus_tag="ACHBV5_000753"
     CDS             24894..25298
                     /locus_tag="ACHBV5_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HFM9966593.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWSEVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            25379..25461
                     /locus_tag="ACHBV5_000754"
     tRNA            25379..25461
                     /locus_tag="ACHBV5_000754"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25410..25412,aa:Tyr,seq:gta)
     gene            25767..26207
                     /locus_tag="ACHBV5_000755"
     CDS             25767..26207
                     /locus_tag="ACHBV5_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HFM9966594.1"
                     /translation="MSGLRIKQKRFADEYIISGNATEAYKKAGYRVSSDRVAGVEGHK
                     LLKNPKIKSYIDERLKQLDSEKIADQQEVLGYLTSVMRGETQEQTLISIGELGQTITD
                     IDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDISD"
     gene            26185..27483
                     /locus_tag="ACHBV5_000756"
     CDS             26185..27483
                     /locus_tag="ACHBV5_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HFM9966595.1"
                     /translation="MSQTYQIKQNDIVVDLPKTVGAGYGQFWRSRSLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDIGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFNKDELLQDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAESRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            27495..28964
                     /locus_tag="ACHBV5_000757"
     CDS             27495..28964
                     /locus_tag="ACHBV5_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0046798 - viral portal complex [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0051027 - DNA transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFM9966596.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHNTESSRLKNLKSYYM
                     GDHAILNHKRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMTELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNKD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
     gene            28873..30276
                     /locus_tag="ACHBV5_000758"
     CDS             28873..30276
                     /locus_tag="ACHBV5_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HFM9966597.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEI
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPENEIKHLQSFSWVGDGSTYSTDIWKNTGKLTSSIKDELLISLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLSYEEADIEKYIFVAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKVEYVPADM
                     TYKEWYSKYVDGNRESIKRKAFDKTIKDGIIVSVSGTTIGHTPPGKIGLPNSVVQHNA
                     TNGDVLGRTYYDARGFKTKDVHFTNHKQPARHPYGKIGEHAHDFVFDDEGKFVSRSTR
                     ELTDDERKENQDILWRY"
     gene            30264..30491
                     /locus_tag="ACHBV5_000759"
     CDS             30264..30491
                     /locus_tag="ACHBV5_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HFM9966598.1"
                     /translation="MAILDDLQALYDNGWDASFNYNGQVCGIFPNSIYDVVVIIADDE
                     YRASSFDDLISLQIEGKTLPEIMNEVEVQYG"
     gene            30640..30852
                     /locus_tag="ACHBV5_000760"
     CDS             30640..30852
                     /locus_tag="ACHBV5_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966599.1"
                     /translation="MEEWKERFKKEYYELKERFQKLDMMIGKYEKGQLEFESKCPIDS
                     LKGQRSTMWNYLRILEQRAKIEEIKL"
     gene            31022..31606
                     /locus_tag="ACHBV5_000761"
     CDS             31022..31606
                     /locus_tag="ACHBV5_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HFM9966600.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMKQAPV
                     DSDGITKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            31613..32458
                     /locus_tag="ACHBV5_000762"
     CDS             31613..32458
                     /locus_tag="ACHBV5_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019028 - viral capsid [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HFM9966601.1"
                     /translation="MTAGQTKLATMVNPEVMADMVAAKLPKLIKFTPLAYVETKLEGQ
                     PGSTLTVPAWEYAGDATEIEEGQAITPDQLTTKKTTMTIKKAGKGYEITDESLLSGLG
                     DPLGQATYQLGLAIANKIDNDLVAVAKTATQHITETPTTLEAIDKALDIFEDEEDAQY
                     VAIINPKDATKLKTAVAKEWIKGSELGANMVVSGTFGEVDGVQIVRSKKVDEGKGFLV
                     KVSPSQTQTDDANKYGAFVILLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGGA"
     gene            32470..32652
                     /locus_tag="ACHBV5_000763"
     CDS             32470..32652
                     /locus_tag="ACHBV5_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HFM9966602.1"
                     /translation="MSLLLRRHYIQEEQVNQYSDLENKTLEELKDLAKEAGVAGAYKL
                     TKAEIVEVLEELKSEI"
     gene            32642..32830
                     /locus_tag="ACHBV5_000764"
     CDS             32642..32830
                     /locus_tag="ACHBV5_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966603.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVT
                     ISDVLEKILPEPEFLEED"
     gene            32832..33143
                     /locus_tag="ACHBV5_000765"
     CDS             32832..33143
                     /locus_tag="ACHBV5_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HFM9966604.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTDLLQRIRMHRLARVAGHVFEA
                     E"
     gene            33124..33462
                     /locus_tag="ACHBV5_000766"
     CDS             33124..33462
                     /locus_tag="ACHBV5_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966605.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            33437..33952
                     /locus_tag="ACHBV5_000767"
     CDS             33437..33952
                     /locus_tag="ACHBV5_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HFM9966606.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            33949..34317
                     /locus_tag="ACHBV5_000768"
     CDS             33949..34317
                     /locus_tag="ACHBV5_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966607.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGIVDLHSELVFQFRMEN"
     gene            34320..34733
                     /locus_tag="ACHBV5_000769"
     CDS             34320..34733
                     /locus_tag="ACHBV5_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HFM9966608.1"
                     /translation="MLANGITLSYGETKDSYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVIFEG
                     QVSVKLGGGGVNAVIDFTLKIALQSNLTFTDGIGG"
     gene            34738..35118
                     /locus_tag="ACHBV5_000770"
     CDS             34738..35118
                     /locus_tag="ACHBV5_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6096 family protein"
                     /protein_id="HFM9966609.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSLEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVDK"
     gene            35157..35507
                     /locus_tag="ACHBV5_000771"
     CDS             35157..35507
                     /locus_tag="ACHBV5_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966610.1"
                     /translation="MFLDIEGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYR
                     LSQMISNHVSLLLSKDAKAFEFWEYAPELFVEEQQAVEQERQKQALLLHKERMREFAE
                     RHNRKRKEEVNGNS"
     gene            35494..39147
                     /locus_tag="ACHBV5_000772"
     CDS             35494..39147
                     /locus_tag="ACHBV5_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966611.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSSSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIESTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIERIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERITRALVALFDNIGNISEAVGNIAQDFSSTFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVAPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPILALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFGETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICRAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTSALANIGAWFTDIFQKAWTGLTNIFSKLGLWFGERWADVTSVLANVSSWFGN
                     MFTSAYNAVKNAFSSIGGFFSGVWSTVQSIFVNAGQKVGSAVGGAFKSAVNAVLGTIE
                     NVVNDFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARGGIVDSPTIAMIGEAGKEA
                     VVPLENTGFIQTLGRVVSSAVVNAMAGISPQGGFSSDGDIVIQIAGHEFGRVAIQEIN
                     KEHERAGQTLLKI"
     gene            39156..39506
                     /locus_tag="ACHBV5_000773"
     CDS             39156..39506
                     /locus_tag="ACHBV5_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6711 family protein"
                     /protein_id="HFM9966612.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSKFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     LKPWSGAKFNLVER"
     gene            39511..>40886
                     /locus_tag="ACHBV5_000774"
     CDS             39511..>40886
                     /locus_tag="ACHBV5_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HFM9966613.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGEYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMTTGRSLELDNVFITQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFIFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGFEAKIQAQIEAADKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKEAKRKAEEALRNAGASSSLAQESKRIGLDSVARLEAFKSQ
                     TTSAQTALS"
BASE COUNT        13133 a         7132 c         9231 g        11390 t
ORIGIN      
        1 atttgaaaga gggatgtgat agtagcaccc tctttttctt tgttttatga tagttcatcc
       61 tcgagtaaat tcaagatctt gctcggaaat gaagcttata tagtagattg aatatagaca
      121 aagaccttgt gattggtaaa acattttaga aattcattta cctttcctaa tcgacttggt
      181 ttcatcttat ttcaatctat tatagtattg gggaatttct tcaaaccaca tcagcttggt
      241 cagttctacc tgcgacctca aaacttgtgc tttggtcaag ctgggtttag tttcctagtt
      301 tgctgatgga tttccattga ctataagcat ccaaccctct tttttgtctt ctaaagaatt
      361 cttaaattat cagtctattg caacttttct catataagtt ctttgtcttg ctattggttt
      421 tccttagtag tatactaagg tagtaatcat taagaagtgg ttacaaaaaa taatgaatga
      481 ggtaaagaaa atggtagaat tgaaaaaaga agcagtaaaa gacgtaacat cattgacaaa
      541 agcagcgcca gtagcattgg caaaaacaaa ggaagtcttg aaccaagctg ttgctgattt
      601 gtatgtagct cacgttgctt tgcaccaagt gcactggtat atgcatggtc gtggtttcct
      661 tgtatggcat ccaaaaatgg atgagtacat ggaagctctt gacggtcaat tggatgaaat
      721 cagcgaacgc ttgattacac tcggtggaag cccattctct acattgacag agttccttca
      781 aaatagtgaa atcgaagaag aagctggtga ataccgtaat gttgaagaaa gcttggaacg
      841 tgttcttgtt atctaccgtt acttgtcaga acttttccaa aaaggtttgg atgtcactga
      901 tgaagaaggt gacgatgtaa caaacggtat ctttgcaggc gctaaaactg aaacagataa
      961 aacaatttgg atgcttgcag ccgaacttgg acaagcacct ggtttgtaag aaataaggaa
     1021 acatagataa atctgtagga aatttcttac agattttttc tattttgtaa gctattccaa
     1081 accagtcttt ttttgagttt tttgataaaa tagtactatc agtgaaaagg atggaagcat
     1141 gactaagaaa atcgtagcta tttgggccca ggatgaagag ggtgtgattg gtaaggaaaa
     1201 tcgtctgcct tggcatttgc cagcagaatt gcagcacttt aaagaaacaa ctctgaatca
     1261 tgctatcttg atggggcgtg tgacctttga tgggatgggg cgtcgcttgc ttccaaaacg
     1321 ggaaaccctg attttgacgc gtaatccgga agaaaagata gatggggttg ctacttttca
     1381 ggacgtccag tctgttcttg actggtatca ggatcaagaa aagaatctct acattatcgg
     1441 tgggaagcaa atttttcagg cttttgaacc ttaccttgat gaagtgattg tcactcacat
     1501 tcatgctcgg gtggaaggag atacctattt ccctgaagag cttgacttgt ctctttttga
     1561 gacagtttca agcaaatttt acgccaaaga tgagaagaat ccttatgatt ttaccatcca
     1621 ataccgcaag agaaaggaag tctaatggaa cggagtttat ttggtctatt cacggctttt
     1681 ctgtgtttca tctgctttct ggcaggagca caggcttttc gtaaaaagcg ttacgggctt
     1741 tctatcctcc tttggttaaa tgcctttacc aatctggtca atagtattca tgctttttac
     1801 atgaccttat tttagataga atgacagtat agaatggaag gaaatcatgt ctacaaatag
     1861 aaaaaatgat atgatggttt attgctcatt ttgtggcaaa aaccaagaag aagtacaaaa
     1921 aataattgct ggcaacaatg cttttatttg taatgaatgc gtggagttag ctcaggaaat
     1981 cattcgagaa gaattggttg aggaagtctt ggcagacttg tctgaggtgc caaaaccaat
     2041 tgaactcctc catatcttga accactatgt aattggtcaa gatcgtgcca agcgtgcctt
     2101 ggcagtggcg gtttataacc actacaaacg catcaatttc cacgatacac gcgaagagtc
     2161 agaagatgtg gatttgcaga agtcaaacat tttgatgatt ggcccaactg gttcagggaa
     2221 aactttcctt gcccagacct tggctaagag cttgaatgtg ccttttgcta ttgcggatgc
     2281 gacagctctg acggaggctg gttatgtggg tgaggacgtg gaaaatatcc tcctcaaact
     2341 cttgcaggtt gctgacttta acatcgaacg tgcagagcgt ggcattatct atgtggatga
     2401 aattgacaag attgccaaga agagtgagaa tgtgtctatc acacgtgatg tttctggtga
     2461 aggggtgcaa caagcccttc tcaagattat cgagggaact gttgctagcg tgccgcctca
     2521 aggtggacgc aaacatccac aacaagagat gattcaagtg gatacaaaaa atatcctctt
     2581 catcgtgggt ggtgcttttg atggtattga agaaattgtc aaacaacgtc tgggtgaaaa
     2641 agtcatcgta tttggtcaaa ataataaggc gattgacgaa aacagctcat atatgcaaga
     2701 aatcatcgct gaagacattc aaaaatttgg tattatccct gagttgattg gacgcttgcc
     2761 tgtttttgcg gctcttgagc aattgaccgt tgatgacttg gttcgcatct tgaaagagcc
     2821 aagaaatgcc ttggtgaaac aataccaaac tttgctttct tatgatgatg ttgagttgga
     2881 atttgacgac gaagcccttc aagagattgc taataaagca atcgaacgga agacaggggc
     2941 gcgtggactt cgctccatta tcgaagaaac catgctagat gttatgtttg aggtgccgag
     3001 tcaggaaaat gtgaaattgg ttcgcatcac taaagaaact gtcgatggaa cggataaacc
     3061 gatcctagaa acagcctaga ggtgactatg gaacttaata cacacaatgc tgaaatcttg
     3121 ctcagtgcag ctaataagtc ccactatccg caggatgaac tgccagagat tgccctagca
     3181 gggcgttcaa atgttggtaa atccagcttt atcaacacta tgttgaaccg taagaatctc
     3241 gcccgtacat caggaaaacc tggtaaaacc cagctcctga acttttttaa cattgatgac
     3301 aagatgcgct ttgtggatgt gcctggttat ggctatgctc gtgtttctaa aaaggaacgt
     3361 gaaaagtggg ggtgcatgat tgaggagtac ttaacgactc gggaaaatct ccgtgcggtt
     3421 gtcagtctag ttgaccttcg tcatgacccg tcagcagatg atgtgcagat gtacgaattt
     3481 ctcaagtatt atgagattcc agtcatcatt gtggcgacca aggcggacaa gattcctcgt
     3541 ggtaaatgga acaagcatga atcagcaatc aaaaagaaat taaactttga cccgagtgac
     3601 gatttcatcc tcttttcatc tgtcagcaag gcagggatgg atgaggcttg ggatgcaatc
     3661 ttagaaaaat tgtgaggaaa agaaaatggc aaaaacaatt catacagata aggccccaaa
     3721 ggctatcgga ccctatgttc aaggaaaaat cgttggcaac cttttgtttg ctagcggtca
     3781 agttccccta tcccctgaaa ctggggaaat tgtaggagag aatatccaag aacagacaga
     3841 gcaagtcttg aaaaacatcg gtgctatttt ggcagaagca ggaacagact ttgaccatgt
     3901 tgtcaaaaca acttgcttct tgagcgatat gaacgacttt gttcctttta atgaggttta
     3961 ccaaacggcc ttcaaagagg aattcccagc tcgttcagct gtggaggtag ctcgtcttcc
     4021 tcgtgatgta aaagtcgaaa ttgaagtcat cgcagagatt ggataagcta gttgaagttt
     4081 ggtgttgcca aacttctttt gatataagga gaaaaagatg acaaagaaac aatttcactt
     4141 ggtgattgtg acagggatga gtggcgcagg gaaaactgta gccattcagt ccttcgagga
     4201 tctaggttat ttcaccattg ataatatgcc gccagctctc ttgcctaagt ttttgcagct
     4261 ggttgaaatt aaggaagaca atcctaagtt ggccttggta gtggatatgc gtagccgttc
     4321 tttcttttca gagattcaag ctgttttgga tgagttggaa aatcaagatg gtttggattt
     4381 caaaatcctc tttttggatg cggctgataa ggaattggtc gctcgttaca aggaaaccag
     4441 acggagtcac ccactagcag cagacggtcg tattttagat ggaatcaagt tggaacgtga
     4501 actcttggca cctttgaaaa atatgagcca aaatgtggtg gatacgactg aactcactcc
     4561 acgtgagctg cgcaaaaccc ttgcagagca gttttcagac caagaacaag cccagtcttt
     4621 ccgtatcgaa gtcatgtctt tcggatttaa gtatggaatc ccgattgatg cggacttggt
     4681 ctttgatgtc cgtttcttgc caaatcccta ttatctacca gaactgagaa accaaacggg
     4741 tgtggatgaa cctgtttatg attatgtcat gaaccatcct gagtcagaag acttttatca
     4801 acatttattg gccttgattg agccgattct gccaagttac caaaaggaag gtaagtccgt
     4861 tttgaccatt gccatgggat gtacgggtgg acaacaccgt agtgtggcat ttgctaaacg
     4921 cttggcgcag gacttatcca agaattggtc tgttaatgaa gggcatcgcg acaaagaccg
     4981 cagaaaggaa acggtaaacc gttcatgaga aaaccaaaga taacggtgat tggtggaggg
     5041 actggaattc ccgtcattct aaaaagtctg cgggaaaaag atgtggaaat cgcagctatc
     5101 gtgacggtgg cagatgatgg tggttcttca ggtgaactcc gaaaaaatat gcaacagttg
     5161 acaccgccag gtgatcttcg taatgtcctt gtggccatgt cggatatgcc taagttttat
     5221 gagaaggtct ttcagtatcg gttctctgag gatgccggag cctttgctgg ccatccattg
     5281 ggaaatctca tcattgctgg cttgtcagaa atgcagggtt caacctataa tgccatgcag
     5341 ttattgagca aatttttcca tacaacaggg aaaatttatc cttccagtga ccatcctttg
     5401 acccttcatg cagtctttca ggatgggaca gaagtggctg gagagagtca tattgtagac
     5461 catcgaggca taattgacaa tgtctatgtg accaatgccc taaacgatga tacgcctctg
     5521 gccagccgtc gagtagtgca gaccatcctt gaaagtgaca tgattgtcct agggccaggt
     5581 tccctcttta cctctatttt gcccaatatc gtgattaagg aaattgggcg ggctcttttg
     5641 gaaactaagg cagaaattgc ctatgtctgc aatatcatga cccaacgtgg ggagacggaa
     5701 cactttacag atagcgacca cgtggaagtc ttgcatcgtc accttggtcg cccttttatc
     5761 gacactgtct tggtgaatat tgaaaaagtg cctcaggaat acatgaattc caaccgtttt
     5821 gatgaatact tggtgcaagt ggaacacgat tttgtaggtc tttgtaagca agtttcgcgc
     5881 gtgatttcat ctaacttcct tcgtctggaa aatggcggtg ccttccacga tggagatttg
     5941 attgtggacg agttgatgcg cattatacag gtgaaaaaat gagtttcaca gtagcagtaa
     6001 aagaagaaat cctgggccaa caccatctga gctggcatga attatctgcc attatcaaaa
     6061 tgtctggtag catcggtctc tcgacttcgg gcttgacttt gtcagttgtg acagaaaatg
     6121 ccaaactggc ccgtcacctc tatgagtcct ttctccattt ctatgaaatc aaatctgaaa
     6181 ttcgtcacca ccaacggagc aatcttcgca agaatcgcgt ctataccgtt tttacagatg
     6241 aaaaggtgca ggatttgtta agtgatttgc acttggcaga ctctttcttt ggcctggaaa
     6301 caggtattga tgaggcgatt ttatcggatg aggaagcagg tcgtgcctat ctctgtggcg
     6361 ctttcttggc aaatgggagc attcgtgacc ctgagtcagg caagtaccag ttggaaatca
     6421 gttctgttta tctggaccac gcgcaaggaa ttgcctccct tctccaacag tttttactgg
     6481 atgccaaggt gcttgagcgc aagaaggggg ctgtgaccta tctccagcga gcagaagaca
     6541 ttatggactt cttgatagta ataggagcca tgcaggcacg tgatgatttt gagcgggtta
     6601 agattttgcg agaaacccgt aacgacctca atcgggctaa taatgccgag acagctaata
     6661 tcgctcggac agtttctgcc agcatgaaga ccattaacaa tatcagtaaa atcaaagata
     6721 tcatgggctt agaaaatttg ccagtagatt tgcaggaagt ggcgcaactg aggattcagc
     6781 acccagacta ctctatccag cagttagcag atagtctcag cacccctctg accaaaagtg
     6841 gtgtcaatca cagactcaga aaaatcaata agatagcgga tgaattataa cgatataaag
     6901 caaccccttg aattatcaat atcttcaagg ggttttgttg tgttatgaaa tcaaaaaggg
     6961 gcaatcaagg ggcagaatta aaaaatagta tctaatttat tgaccagttt atcctccata
     7021 tcctcagtag tatgagaata gatttccaaa gtcatttttg catttgagtg cccaactcga
     7081 tccattattg attttattgg gaggtcagac tctgctaaaa acgaaatatg agaatgccta
     7141 aaaatatggc tagataagtt tttttctatt ttggcctgtt ttccatattt ttttaatatc
     7201 tgtatgaagc aagctattgt tgtaggttga ttccattttt caaaacagaa aatataatca
     7261 tcgcttgaca atggctggaa acgttcgcta agtcgtacta tttgtctttg aatagcttct
     7321 atgacactct ctgatacttt gattgtccgt attgaatttg tagtctttgg tagcgtcttg
     7381 attttgttta ctgaatcaaa attacctgtg atctcaattt tgttgttttc gaagtctata
     7441 ttcttcagtt gtaaggcagt taactcacca tatctcatac cagttaatgt cagcacaaga
     7501 accatatcag cgtacttttg gtgatattct cgacgattaa ggacatcgac aagtgctttt
     7561 atttcttgca tggtgagaaa gttgttacgc tttttttcca gttcttctaa agtctttggt
     7621 ttttgaggaa tcgtagtata atcaacctcg ttgttttcaa tgtaagagta ttgaacagcg
     7681 taattaaaga tacctctgag cctatgccgt acttttttag ctgtaatata tccgttgctt
     7741 tcaataattt tttcaatagc ctcttgaaga aaacgcctgt caagattagc aagtatggta
     7801 tcggatggta tgacttcctt catcttctta tcaactgatt tacaattatg ttttgttgat
     7861 tcctttactg tttgcgccca tgatttatag aaaaggttat agatttcttc aaatgtaatg
     7921 ctttctactt gttttgtgct gagtttttta tttatcttct cttgtaacaa gatagcagct
     7981 tgatttcttg cctggggagt tttcttctcc atggttactg aaactttttt taatttctca
     8041 gtatatggat ctttatatcg ctcaaaatat ttaaatttgc catttggcaa ttcttccatc
     8101 cacattgcgt ttacctcact tttttgttaa aatgggtaca agaaaactac ctttttaatg
     8161 gttgtttcct atacatgatt tcctcacact ctccttggcc aaaatttgag tgtggggatt
     8221 ttttggttgc tatctcgtca gataataaaa taaggtgtac ctcttagaag tacaccagac
     8281 gattttatcc ttgacgaaca aggctttttt acattcttag tgtatttctt tttttaattt
     8341 ctgtcaagca gttatttcct aaatggaaat agttggtttt aatttatact tttggttcat
     8401 tacggtgcca atcattagga aaacctaaag actggttgat tacattgatg tctatagaag
     8461 gcagcttttt ctctagtttg ataacttttt ttctaagagt attccacaaa atgttgaatg
     8521 ctgctttact aataaagcat tgaaggctaa taattgttga atatacagtt tttctactgt
     8581 catctcccat caagatctct ttgttatgaa tcgtttccca aaacgtacta ttagaacggc
     8641 atctgaagtt taataagcga ttattgtgag cgcatttgtt tcgtacctcg ttaatatttt
     8701 ttagaaaaga tatcaaggtt tctggtggga aaacatcgtt aaagtcaggt atgtttgtgc
     8761 ttataaaact tactaaatcc cgtgcgattt cattttggag tgaattaggc aggttttcaa
     8821 taatcgtgcg taaatctcca aactctagat aatcagttag tacccagatt gggacatctg
     8881 aatgagtatg tgcgtagtgg tgaattgaat ttcctctgta tcgcttgttt gtgtttatga
     8941 ttttggatag ttttgataca ataaatccca cgtctaatat tttattatct gcataagaat
     9001 tggtgtttaa ataagcgtat ttttgactgg ggtaagcttc ggcgaatctg tgagcagtga
     9061 ttgacttgat atggtgttca gcttcaagaa tagcttgcaa aatggctcgt tttacatctt
     9121 tgtcaaatgt atagagactt gaaacttcgt caaatgtgac gccgtcaata taagtgtcag
     9181 taccagggtg ttgaaaaaac ttactgtatc cattgataat attgtagtaa ttgttactta
     9241 gcaggtactt agctgcttta gattcatctg taatggataa ccctctgatt tttagtgttg
     9301 cgatttgttc ctcgattgtt ttaaatggct tcaaaaaaac tcccccattc taatttagaa
     9361 tgaaggagtt tccccgtatc ggtccccgta gagatcccga cgctttttct ctaatgaatt
     9421 cattctaaat gattttttta aaaaagtcaa ctgtttttta atatttttaa aaaataattt
     9481 ttttattccc ctctatacac cccgactact gcataaatct tgatgtgtgt gtcttcggct
     9541 ggtgggaagt ctaggatgat gtcttcgtac ttgtcattga gtgacactag gcgtaagcgt
     9601 ccgttttcgg tatatatctt cttgaagtaa gaacggtctc catatgcgat aattgctaaa
     9661 tctccgttgt aggtagtcag tcctttgtct actaaataga gaatgtctcc gtcttggtag
     9721 tcgggttgca tggagtctcc actgaccttg gtcgcaatat cgtggcgtgg tggtcgctcg
     9781 tcaacctcta tagtctctct gtctgtatcg tcgtacccaa atccatagtt aaatccagaa
     9841 gctgctgccg tctcagatac aacctcaact tggtacaagc tgataacttc cgatacttcg
     9901 tttatcttcg tttcttcttc gttttggctc tccagaagct cctcagaggt ccgtagcacg
     9961 attttttgat tgggtggggt taattgcact accttatcca ttatctgctg tgtgagcgaa
    10021 tctggagcgt ctggcagtga gttggtggat tcttctttaa aagtagtatc tatatctgat
    10081 tttttaacac cgaaataatc agccagtttt tggataacac caaaagaagg agcgcttctt
    10141 aacttcatat agtctgtcat agtacttgct gtaattccaa cttctttagc caactctttt
    10201 tgggtgatgc cacgttgctt tctaaagtgt gtaatatttt cagcaataat ttgcattcgt
    10261 tttttttcgt ccatttacga ttacctcgta ttttttataa ttacattata tatcattttt
    10321 gaatgataaa caatcaaaaa tacgaaaaaa tcctattttt ttgataaaaa ctattgacaa
    10381 tacgaaaaaa tcgtattata attaaatcaa gcttaaggaa aaggaggtaa ggcaaatgaa
    10441 cgaactagaa agaacagccc tcaatgagat attgaggact gtgacatata tagctgagaa
    10501 gttggatgaa gtagattcta agatttcttt gaacgattca caagctcttg agcatcaagg
    10561 aaattgagtt tcatttccat gtagtgaata actccgtgta ggtagttctt taggtctgta
    10621 aaacctttat caggattatt tctatagtaa tgaccttcgt cgttaccgat ataagcagat
    10681 gcaagcgcaa atgttttaag gtcttcatcc ttgatatatt tttcaataac ttgttttaat
    10741 gacattttaa tgattttatc ttcatcatca ggatttgtaa caatggagaa atctttaaca
    10801 aagaactcaa gcgccttacg gtatccaata cctgcaatgt ggtctagttg ttcgtgttca
    10861 gctttcagtg cttggacata gatttgctta ccaattggag aaactatctc tacatcgtca
    10921 gatataggta tatcgctcgg aagattaggg attactttga tatgttcaat ttcgtatttt
    10981 tcggtatagt cattgattaa aaatcttgta gctataaact cctctgtcca aaagtgctta
    11041 caacctaagc atctacatgt taatactaag cttgttttat tttctccaag agaaaaataa
    11101 gaagagttca caagatctgg attggttggt tttttacaat ttgggcaaat gtcttcaacg
    11161 gttacaggcc tagaaacaga agaatttact ttcactcgaa atatcataag atttctccaa
    11221 tcgttttatt ttgattatac catatttgaa agggggtgag gaaatgagac caagacgata
    11281 tccgtatagt gggaaaaaag agtccacctt cgtaaaggca gaccctgagt taatgttgaa
    11341 tatcaataag attgatgttg gaaatataca agcgaaaaat atatttggaa aaatttaagg
    11401 agtaggagga tggatgaaag aaaatataga acatcttcat gaacgcataa agcattttca
    11461 gtcattgatt gcttatatgt ctgagcatga gaaaaagtat tatttagaaa aagattggtt
    11521 cgataaccca accctaattt ctatagaaga cgcaaaaaaa gaagtagaac tactttaaca
    11581 gaaaggaggt aggaacgtgc agtggacttt agaagctatg agaatcaaca aaggacttac
    11641 tcaagcagag ttggcagaaa aatttgaagt ttcaagtcaa acaattgcta gattagaaaa
    11701 agatagctct gatatcggtt atcagctatt gaaaaaatac atgttttttt tcaatgtgaa
    11761 attcgatgat atttttttag ggaaaaaata cgaaaatttc gtaaataact agaaacaaaa
    11821 aaataagaag gaggaacaca tagatggaaa gcgttcttga aagcttgaaa caagaaaaag
    11881 accacctcga aaaaatcatt aaggtagtta cctctggtgg taaatttctg agattgccgt
    11941 atcaaaaaaa gtcacgctcg attagtgaga atctgaaatt gatttctcaa aatcttgata
    12001 aattgagcga gcaagttcaa caaaccacga atcagcattc atgatttcaa gatgacgaaa
    12061 gaaacctgtt ttgatttcca gtttgatatc atgttacagc gactcgataa agcgattagt
    12121 gattaaattt ttgagatgta agtttttttc atgtcaaact ttttcatgtc aaatttttta
    12181 cactaataaa tattaactaa caacaagtat taaaagacaa ccagtcctac ttctctaaat
    12241 aaaagagagg gtagaaaaaa taaatacaaa ggaggtgagg aaatgagacc aagacgatat
    12301 ccgtatagtg ggaaaaaaga gtccaccttt gtaaaggcag accctgagtt agttgaaaaa
    12361 cttttaagaa acactagttt tcttgagcgt ttacaaaaaa agcctatcaa ttttcagata
    12421 gactcagaag aatttaagcg tcttagctat gaagccattc atgatacttc tcaagtaact
    12481 caatagtagt tattacagaa gtcaaaccac tgaccttccc cagttgcaat ccgtctgtat
    12541 ggtcaatctg tttagtagct tcattagctt tagcagagat agcttgcata tcttcagctg
    12601 ttaaagattc tcgaaaatct ttaaaggatt tcataaaaac tcctcctttc tattggaatt
    12661 ttgactaaaa cggtgagagg tcctagtcga gattattata gcaatttagg aggatattac
    12721 atcggtcttg aggctgattt ttggaggcaa tattggaaga taaaatcata gaacttgctg
    12781 attacttcat cagcgaatct acaacgtaca gagaagcaaa aatagcgtgt gagaagctat
    12841 tgaaacaagt cagccacgag attgaactca gggcgatgga aagtaggaca gtatgaaaga
    12901 agcagtaaag gaatttctaa aattcaggag ccgatttaca aaaatagaat ggtttgaaat
    12961 caaccaagct gtcgaagctc gtttaaatca aaaagccgac cagttgaaac tggacgacgt
    13021 agatttagaa atcatttcta gcagactaga aaaagttatc tagaaacgat ttgaatgaac
    13081 attggatgga tacgatagtc agcgccacga tagtgaatgt agatataatc ctgatggtac
    13141 atcgagtttg cttcaggttt agaaattggt gagtagagtt ctgcattttc ttcccaccaa
    13201 atgtaaggac tagccatatt tggtcccatt acacaatcgt cgtcggctga taggttcacc
    13261 caatttccgc aaagacatgc gtgaatttca gtcataatat tacctccttt ctggtttcat
    13321 tatagcagaa aaggagatag caaaaaagca cctgacggaa atcaggcgca tacttaaata
    13381 ttcaacatga ttataacacg aaaggagcaa aaatggaagc agttgaaatt gtaagaatta
    13441 aagatgtgat tattgaaaaa gtctctgcta atgatgaaga gttaaaacgt atctttggat
    13501 gttcaaaacg acaagcagga gagcgaagaa gagaaatgca aaaactccct agtcagcaaa
    13561 aacatctttt ggatagtgga caacttgtaa cgattaaagg tttctatgaa tacttgcaat
    13621 atcgtggaac taaagcttgg aaaaaagaaa tggaaacaag caagaaaatg aggtcagcag
    13681 gatgaaccta ctatcaagaa tcaaaaacta tttttcggaa gaggtcaaag aaactaatct
    13741 cgactggaaa gaggtcgctt tagacctcaa tcaatcacta attgaaacac aggaaaaact
    13801 tcaagaagcg aatcaagaaa tcgcagactt gaagaaaatc gtagcaatct ataaagaaaa
    13861 ggagaaagaa aaacgatgga atatatttac ctggtaacaa tcgtaggaat tggactatgg
    13921 tcgctagtaa ataaactaga tgaccacgct gaaatgaaac aaaaagagcg ccagctgatg
    13981 gcaaacaatg tcgcacggat gaatctgaga aattcagata agcaatttac ttatgatgta
    14041 gaaccgcctg aagggttgaa ataaggagga gaaacatgac tcaagctgaa cgaattaggg
    14101 aatattatag agagcaccct gctgcctcat atgatgaagt ggctgaggtc gttggtacaa
    14161 caaatagtaa tgtgagagcg aacctggcca aagacatcaa ggcaggcaga tgcgttcgct
    14221 tggaagataa gtcatacgat tactcgcctt actataacca tacacaggca ctcactgagt
    14281 tggttgactg gaagaatgac aacagacgtg agtgggtgga tatgctgaca agagcagcag
    14341 agaaagaaac ggatagcaac gttatgcgtt tgttaatcaa agaagcaaat aaattgatga
    14401 aagaggtgac taagtagatg gtacgaaata aaataggtga tttaactaac acgctcttcg
    14461 ctcaattaga gactctggat gatagggatc ttacagcaga tgaattaaaa gtagaattac
    14521 accgctcgaa acaaatggtc gcaatctcag gtcaaatctt acaagcaggt caattggcgc
    14581 tagatgctga aaaattcaaa gacaaggtag gtgaagtcaa tgccccgatc gctttgctgg
    14641 aaggatgagt acacggagta catgcatgaa atatgccctg gtcgtttaac tcctgaagta
    14701 accaggttgc tgaatgaaaa atttggtacg aattataaca agagtcaaat cggtggcgta
    14761 cgcaaacgtc tagggttagc agttggaaaa gtctatcaag gtcgattgct gacaaaggag
    14821 caacatgatt atcttgtatt gatccaaaaa aataagattt ctcgtaatgt cgcaaatgaa
    14881 atgaaccaaa aatttggctt atcgctaact gagaaacaga ttaagagtta tcggagaaat
    14941 aataatctac atagtggttt gacaggaaga ttcgagaaag gtcagactcc tcacaataag
    15001 gggaagaagt accccaatat gccaaaaaac ggcgggcagt tcaaaaaagg taatcgacct
    15061 ccgaattatg tacctgtcgg tactatcaac tacacaacaa acggttatcc aaaagaaaag
    15121 attggagaac ctaatcaatg ggttttgaaa caccgcaagg tttgggagga ccatcacggg
    15181 ctgataccaa aagggtactc aatcgttttt ctggacggtg ataaaacaaa ctatgatatt
    15241 tcaaatctgg catgtttatc taagaacgaa attgctagaa tgaatcaaaa tcatttattc
    15301 acgtccaacg ctgatttgac taaatcaggt attggactaa caaaacttac aaataaaatc
    15361 agagaggtag aaaaaaatgg ctagtttata cgaactaaca ggtcagttcc tgacaattta
    15421 ccaattggat atcgatgacg aaacaaaagc agacacgctt gaggccatcg attggcaaga
    15481 acaatttgaa cagaaagcag aaggatatgc ccatgttatc aagaatctag aagccgacgt
    15541 ggcaatgtac aaggctgagg aagagagctt caaagccaag aaacaggtgg cacagaaaaa
    15601 gctggattat gtcaaggata acattatggc agctatgaat gtcacggggc aaaccgaagt
    15661 taagagtggt gccctgatta taaaaattgc taagaatcca gaatcagtca aggtcaacga
    15721 agacgacctt ccgaaaaaat attttacaaa aaaagtgacg cttgcgccgg acaaaaaaac
    15781 actcaaagag ttgcttaaat ctggcaagaa agtcaaaggt gcggagcttg tccggacaga
    15841 aaagttggtg attaagtaat ggaattgatg aataaaacac gagtaacaga ttcactagca
    15901 gttgtgattg gaccagaatc gattgaagta cttgttactg aaggttttct atttgatgtt
    15961 gcgattcgtt ttgtaaaagt agacgaaaca aatcttgatc aaggaaatga aaagccagta
    16021 ttcactccgg aatacaagct ggtcacagtt gctaaataca aggaaaaacc tatctttgaa
    16081 tcggaggaag atattcgaaa atttgagaag caagcaaaag aagttaaatc gctatttgcc
    16141 tttgcaaagg taaataaaca aaattggttt aacactgccc tttatccagg agtgctgact
    16201 gagaaagttg gtgtttgatg aaaattttag ctattgatcc aagtagtaat aaaattgaaa
    16261 ccagcacaac aggagttgtc ttgttggata atgcaagatt agttgatagc tgggttgtct
    16321 cttatggtat gagaggtttc gctgattggt ttcacgaaat cggaacaaat cttgaattcg
    16381 atgtagttat tgttgaagaa tttaaggcga gggataacga caagtcgaaa gataatagcg
    16441 tggcagaaac catcgcctat atccaacttt gctatccagg tgccattctt caattcaatg
    16501 caggttacaa gtcggatatt ccaaacgatc ttttgaaaat cttagacctt tggaaatttg
    16561 aaaaaagtca tcatcaagat attcgagcag cagcaagact tggattattt tgggcaatga
    16621 gaaatgatat tgaagaagtg gttcatgata tcggaaaggt ggtgagtgag tatcacaata
    16681 acgctaagaa agtggcaagc tgaagcgatt aaaagaagtg aacatttatc taatggaatc
    16741 tttttagagg ctcttggggg cagaggcaaa actatctgtg cacttgctat tgcaaaacat
    16801 aaaaaagcta aaaaaatcat catcacaaac aatcgactag ctattctgaa tggttggata
    16861 gatgcagtca agtttatgaa ttttgataaa ggtgttgaga ttatcattca gacagataga
    16921 tatcttcaaa atcaagtcaa aaaggggcat aaattagatt gtgatgtgct gatagtagac
    16981 gaatggcaga atatgtcttc tgacaaacaa gtggccttat atcgcaaaat aaagcgaaaa
    17041 tacacgatag gtctttcagc gacaccaatt cggaaaaaag gacaaaattt ctatccgctt
    17101 gaaaaaacgg tatttggttg ggcaacccca aataataaat ttgactggca aaagactcat
    17161 ggaaaaatgg tctatgatcc atttagctat tcaaaagaga agtgggaaga ttttcaaaat
    17221 tatgaaagtt atatctcgag cttgcctaat ttcttccgct gggaagagat tgaaggaatt
    17281 gagaatgcag ttgagaataa cggttttgag attaagtttt accaaaagag agtcgcctct
    17341 ggcaatccag aaaaacttgc agaatttaga aaactaaatc ttgtaacagt ggacggcaaa
    17401 actgcaatgg ccaagcaatc gtttggaaga aagacctttg aacgctacct taatcaaaca
    17461 ggcgtagcag tcgattttcc aaaattaaag ccagtaaatg cggatacgcc attgatgtta
    17521 caacttgacg gtttaatcga acgagcacca cacgatatgt tgattgtcag taaatctaag
    17581 cagattgtca acgtcattag cgagcgccat cctgaaattg gaatctggac gggcgatatt
    17641 caagaaggac tttataagaa attcgtggtt gctactagtc aagtgttagg tgtcggagta
    17701 gacggcttgc aacacaaata ccaaactatt gtcgtattgg atccagtaga agaaggttct
    17761 ggagaatatg atgattatcg acaattgctc tggcgcataa caggaagtcg tcagcagcat
    17821 gatgtaaatg taattgaatt ttattataaa gaaagttaaa aaaagaggaa aacaaaatga
    17881 ataaaacaac tgaaatgatc gtatttcgta gccgtaaaac tggagaattt cttaattctt
    17941 acaaggacag aagttcttta gcatttgcag ctgacttttg cagcttggaa tattgtttga
    18001 agcttcctcg taaaaaatac gaagacaaca aaaagactta caaggctctt gctgcagctt
    18061 ttgactgtga aattgtcgca gttgaagcgg aatacaaatt gacctatccg aatggatcag
    18121 aagttgaacc tatcaagcgt gaccgttcat caattgagga catgattaag gatattattg
    18181 gaggggttct ctaatggcat ttacacttcc agcaaataaa ccacaagttc ctaaagatac
    18241 cccacgaaat tttttcatct acggcgaaac catgagcgga aagtcttatc ttgcaaatga
    18301 attcccaaat ccaatcgttt tgaacacaga cgggaatgca gaagctaaca ctgttccaag
    18361 cattcagctg atcaatgaaa aagatgacaa gggacgaatt accaattcag taattaagca
    18421 gcttggagat atcttgcttg ctctccagac acagaagcac tcttatgaaa cagtcgttat
    18481 tgatgtaatt gacgatgtta ttgaaatgat taagattgca gtttgtgatg aattaacccc
    18541 agttggtaaa cctcgcttga aatccttgtc ggaaattcca tacggcaaag gatacgactt
    18601 ctttaaccaa gctatcacag aattagtcat tgacctcaaa gcattgccaa tgaatgttat
    18661 ttacatcagc cgtcaggtat ctgaatatga tgacaatggc aatgccacca aagacaagcc
    18721 aagcttgaaa gataagtatg tcaatcttat caatggaaac tctgatttga tgatccacac
    18781 tgaaaaactc ggcaacaact acaaccgtga ggttgaccgc aagcgtaaga cctattatgc
    18841 ggaccaggtt gatgacaagg ccatcttgaa aatcttggca actatccgtg gggctgttga
    18901 gcctgcaaag ggcaagctag cccctaaaaa agaagcagct aagacaacta aaccagctaa
    18961 gaccgaaaaa acaaaagagg cacctaagaa agaagttgac tctgatgatg aactatttta
    19021 agaaataaag gagaatacac atgagcttac tagatatcgc aaaatcaatc aaaaaagagg
    19081 gctttgaccc acgcaaagac agcgccaacg gtcctgcacc aatcccagct ggtacttatc
    19141 cagtagtcct gaagaaagca accttcaacg tatcggacaa aggctgggaa agccttggtt
    19201 atcaatttga aatccgtggc ggtgattaca gtggacgctc tgaatttgca acatttggca
    19261 cactgactga atggaacggt aagaaccttg actgggcagt tgaacgcact atgaaattct
    19321 ttatcaaagc cttggtcctt gctggcgaca gtatgcaagg aaatgaagaa gacggtaaag
    19381 ccttggaaga ggctctacaa cgtaaggcag ttggctctta ctacaacctt gttatctctg
    19441 tgactaaggg gaaagatggc cgtgagttcc gaaactatga ccttgaagaa gaagaagcac
    19501 aaccgctgac tgaagctgat atcgatgaag atgacctccc tttctaaaaa atagcaagtt
    19561 ttgggtcatt gatgaaactg atgaaagatt aggaccattc aatacatttg aagaggctta
    19621 tcaatcgttg ttattttatt taaaaatgac tgaagatgaa tatcagtcaa actatacggc
    19681 ccaggaactt gtttatattt acaaagagga gaaaaaacca tgccgtcgat gaaagaatac
    19741 gcattacagt accaaaagtt agggttctca gtcattccaa tcaatcctaa aaacaagatg
    19801 cctttaatcg aatttgctga taaaccagcc atgactccat ctgagattga aaacttttgg
    19861 gacggctacc ctaatgcaaa cattgcccta aagactacca acttctttgt cattgatatt
    19921 gacaaacacg gcaaatcgaa cggttttgaa tcgctaaaaa aatggaaaca tctaaattta
    19981 atcgaaccga cactgcaagc taagacggct agtggcggta aacatctatt ctacttcaaa
    20041 cgagaagatg agccgatcac tcagatgatt ggattcttgc ctggtgttga tattaaggct
    20101 cacgaaaata attatgtgtt agtcgcaccc tctgccacag ataaagggca gtatgagtgg
    20161 gatctggaaa agtctaagga aggtggcacg atggtcactc cttcaaaata tttaatccag
    20221 tctataaaaa aacagtatgg cgaaactcac ggttataagt atgatggtaa ggacggtctt
    20281 agggatttag ttagacgttc acatactaga gaccgaacac agactacaga tctctttgaa
    20341 accatcgccc ttggttttgg tgatgaaggt ggacgaaatg acaaactagc aaaattcgta
    20401 ggtggtctct tatatcgtgc ggtcgacgat ggtgtagttg ttcaacttgc aagattagca
    20461 aatgcaaata gtccaacccc tttgcctgaa aaggaaatga tgcgtactat tgaaagtatg
    20521 attaaaaaag ataggaggtg attgtgattg gtaatgtagt aagtattgac tcacaaccta
    20581 agatgataac gactgccaag ggagacatca aggccaacag tccaagtaat gtgttgatgt
    20641 ctttcaaagc tgatgatcag ttgagtattt acctaaagca caacgatttt tcccaagagc
    20701 atgaactcct taaagatatc aagatcggca acactctttt taaaaaaggt gagctccctt
    20761 ctaactttga ttcagtcgta aaagtttact ttgaaagtgt gttaggtgtt gctttctcta
    20821 gccaggcgat gctggacggc atggaaactt ttttctcaga acgttcttac aatccagtca
    20881 ttgagtatat ggaaaaggct gctgaaaaat gggatggtcg taaacgaatt gaccgaatgc
    20941 ttcaggttta cctgggggct gaagatatcc ctttagtttc taaaatcgct caaatgtggc
    21001 tagttggtgc agttgctaaa gtttatgatc catacgttaa gtttgactat gttctggatc
    21061 tagtcggtgg acaaggagtt gggaaaacat ccctccttca aaaattgggt ggcgaatggt
    21121 atacggatgc cgtaacagat ttctctaata aagataatta cgacattatg ttaaagagtc
    21181 taatcgtcaa cgacgacgaa atggtggcca gtaatcggat gagctttgca gaaactaagg
    21241 cctttatttc taaaactagc ctacgttatc gtaaaccata catgaaacgc acagaagagt
    21301 ttgccaaaaa cttcatttta gctagaacta ctaaccaaac agaatacctc aaggacaaaa
    21361 ccggtgaacg tcgttttcta ccagttatgg cagatagtaa acggcaaaaa aaacatccaa
    21421 tggaaatcga gccagagaca attgaacaaa tctggggcga agccgttaca atctatcgtg
    21481 ctggtgctga tttgatgttt gatgaaaata cagaggatga actgaatatc taccgtgaac
    21541 agttcatgta tcgtgatgaa gttgaattac aagtgcttga atatcttgat atgcccgtcc
    21601 ctgaaaattg gcaaaactgg tctattcagc aacaacatca atacacaagt aaatatttcg
    21661 ataatagtag cgactttgat cctggaagca aaaaactaga taaggtctca actcgtgaaa
    21721 tgatgtacaa cttatttatg agaaattcga atgacaggaa gctgtcaacg aagattaaca
    21781 tgatcatgga taatcatcct gattggaaaa aaagtgtttt ccgggcagga ggtaaaagta
    21841 caaaagggtt cgtaagagtg aaagattcgg aaaaaactaa tcggtagcaa ttaaaaaatt
    21901 atcggtagtc atcggtagca gttgaggggg agatcggtag cattctaccg ataaaatagg
    21961 acatcggtag cacatcggta gcagtctaac cccttgatat tactgacttt tatttaatat
    22021 ttatatataa tgctactctt ctacctatat ttttaaaaaa agtatataaa ataatagtaa
    22081 taataaagaa agcctataga atagggattc ttgaaaaaaa ctttttactt tttagaattt
    22141 atcggtagca cggtagcagt ttagaaaaaa gaggtaaaaa tgtcatacac agtaacatta
    22201 ttttttgaca acatggtaga cgaaactcac ttttttaaga aagagagtga tgctgccaaa
    22261 tgcaaggctc agttagaaag caagtatcga gggaatcgaa tgtataaagt taagcaggag
    22321 aaattggaag aatgaataag caggaactga ttaaacgtat cgaggatttg ccttatacag
    22381 aggggcctat cgcagataca atcgaaatta atagaaattg gatattgaaa tcaattgaac
    22441 agctagccga atccgaaata ggtcacgcag atgaagctcc acgctacgta aagaacatac
    22501 tagcacgatt gcgagaattg ccattgcatg atagagagtt ttggttaaag gctatcatga
    22561 gcgaatttga acaggatttt agccatgcaa aatggcgaga gggctacgag caaggtaaaa
    22621 ttgagggtat ggttgaacgt gaaaaagtca tagttccgca gtgtgtggcg gaatatatag
    22681 aatttaaaaa gaaaaacaat tttcatgttt acggtgcaat gagagtaatt gaagatcatt
    22741 atgataagaa agttcctgat tggttttacg aaaataacat cgaaaaattc tgtcttgctt
    22801 ggcttgacgg ctacgaggtt gaaaaagaga agcggtattt tgttaagatt aaagggaata
    22861 ttaaagaaaa tatgttggtt tatggagaac ttttgaaaag gtatttcttt acaaaaagct
    22921 ttagtttaga cgatgttata tattcccaca cccgtaaaga actagaaaat gcaaaaatcg
    22981 gctgggtgtt tgattgtgaa gggtttgaga ttgaggaggt ggagtgatga gccttacgct
    23041 aaatagcaca attggagact tagttttggc aatcggagaa attatcgttg gttctgatgg
    23101 taaaaccact acagcgatac tggagatacc tgatcaaagc ttttacttag agattgagct
    23161 taaattgaag gaggaggtca taaattgaaa cgattcatag ctatctggat tctgctatct
    23221 gctggattga atatctggca gagtatctac attaaaaagt tagaagaaaa gcgccctatt
    23281 gtcgtctata aagctgataa cgcaggcgct gagatattcg gtaaagtcgt cgagaaagga
    23341 cggcatggca agctatacac gcttaccatt cgtgactacg gggtgttcgt ggttacgaag
    23401 gacgtgtatg agaaagtgaa agtaggggat gaggtgttac tctaatggat gatattttac
    23461 aagctttagc aaaaatgcta aatatgactg ttgatgaagt aagttctttg cttacaacat
    23521 ttaaagggaa tgcaccacag atttatgaaa tgttcgttaa agaaaagatg ttttatgatc
    23581 tcttcagtct ttttcaaatc atgtcaattg taatatttag tatttctgca gtagttttag
    23641 cagttttaac tctcatatat tttacatacg atggtggttt tgtttattcc tatgatatac
    23701 gtacaggaaa aaccgaggaa gaaattaaat tagaacgcat tgaacggaaa agaaaggact
    23761 taaaaatacc actaaaaatt agttgcattt catcaagcgc aagtttgata acattagtta
    23821 ttgcaattgt tttaaaagca actcttgcac ctaattatat attcatcgtg aatgagattt
    23881 taccaaaatt aacgaagaga taggagttat catgaacgca ctagaaaaag tcgaacaatg
    23941 gtttatcgac cgtgaaatca aagaccgaaa aggtcgctgg attgatggct cgtttgtcaa
    24001 agaggaggat ttggcatgat accgaaattt agagtgtggg taaaaatagg aaaacgtatg
    24061 gttttttcag atgacattct tgctattgac tacgaaaaca aagaaatagt gacacaacaa
    24121 gtttattttg agaatggttt accagacgat agagatatct attgttatga ttttgacgaa
    24181 atcgaactca tgcaatcaac aggactcaaa gacaagaacg gcaaggaaat ctttgaaggc
    24241 gatattgtac gaactactag atttttgggt agagctgacg aaattggcgg tttctatgag
    24301 tatgacaagg aatttatagg gattgttaag cagcttgagg gttcttgggt aattgatacg
    24361 ggcagtgacg cagtatgttt atggactgaa attgaagaaa atgaaatcat cggcaacatc
    24421 tatgaaaata aggagtttgg aggacgcaaa tgagaccttg taaatatcca tattcaggaa
    24481 gaagaaaaaa acaagaaacg ccgtcgccaa tattttctgc acgaccaatt tttgacgaag
    24541 ttccaattgt agaagaagtt aaggttgagt tcggagttga agctagtatg gggcgcatat
    24601 atccagaaac gttaatacat ttagatattt ctggatacgg aaatagagtg cattcagtac
    24661 atcgcttccc cggtatttta ctgagtgttg gtgagtcaat ccaactaaag atgcttttct
    24721 ataaaagact tagaaatttt actacagatc gtttcttgac gtttagagaa tctgattgga
    24781 agttctttat ccgggacctg gtcaacgaat ttaagcatta aaaaaagcca agacactctc
    24841 tgcctcagct aatagttctc gcaaagacta ttatatcaca aaggagacag agagtgaaca
    24901 aggctaaaga gctcttgaaa gagttgcagg atctggacat ggacatccaa agccgtatag
    24961 acgaaattaa cgagcttgag gcaggtttgc tctcaagccc taaatggtcc gaggttaaag
    25021 tccaaggtgg acagactaga aaagttgatg atgtctatac tcagttggta gtgatgaaag
    25081 aggctataga gcaggatact aaagaggtca ttaacagaaa acttgaatta ggtagaatga
    25141 tcaataggct taaaaatcca aagtacaggg cagtattaag aatgacttac atcaacaaag
    25201 gcaccgctga tagcgtttgt tatgatttga atatgagtcg tacaacctac tacaggttaa
    25261 aaaatgaggc ggtcttagct ttggaagaag ttatctaacc tcatagtgag cttatgggac
    25321 tttttggaac agcacggttc taaaaatctg ttagaatggt agtatcaaga attgaaaaga
    25381 gaggtctcag aattggtaga tggttacctg taatgtcagg gggctgtaat ggccttggag
    25441 gttcaagtcc tcccctctcc tttgagtgtt tgtgtcccag aatgagttaa atcttctggg
    25501 tggggattca catatcactc attaactcct atcactcatt aacttaaaaa tggttgcgga
    25561 agcgactgga cctcgcatga ttgcgtagct aattatattc cggataagtt ataagctaga
    25621 gggtttgatt ccctcagagg ttttaaagac tacaaaaaat aaaaaagaag tcaaaattta
    25681 atacgcacgc aaggtagtag tcgccttgca agaaggtcgc acatcgtgtg gctttttttg
    25741 attattcgaa gggtggtgat ggaaaattga gtggattgag aataaaacaa aagagatttg
    25801 cagatgagta catcatctca ggtaatgcga cggaagccta taagaaagca ggttatcgtg
    25861 tttctagtga tagagtggca ggcgttgaag gacataagtt actaaagaat cctaagatta
    25921 aaagctatat agatgaacga ctgaaacagc ttgattctga aaagattgcg gatcagcaag
    25981 aggtcttagg ttatctaact tcagtcatgc gaggagagac gcaagaacag accttgataa
    26041 gcattggaga actagggcag acgattacgg atatagatgt aggagctaaa gatagaatca
    26101 aggcggctga acttcttggt aaacggcata ggctttggac ggataaggta gaggcggatg
    26161 tttctggaac ggtggtgttt gcaaatgagt cagacatatc agattaaaca aaacgatatt
    26221 gtcgttgact tacctaagac agtaggagct ggatacggac agttctggcg ctcaagaagt
    26281 ctttatcgtg tagtcaaagg gtcccgtggt tcgaagaagt ccaagacaac cgctttgaat
    26341 tatgttatcc gtcttttgaa gtatccctgg gccaacttgc ttgttattcg tagatactcg
    26401 aataccaaca agcaatcaac ttatacggat tttaaatggg cgtgtaatgt gttgggtgtg
    26461 actcatttgt ttaaatttaa cgagtctttg cctgaaataa ccataaaagc gactggtcaa
    26521 aaaatcctat tccgtggttt ggatgatgaa ctcaaaatta catctattac agtcgatatc
    26581 ggtagtctgt gttgggcatg gttcgaggaa gcatatcaaa ttgagactga agacaagttc
    26641 agcacggttg ttgagtctat ccgtggtagc ttagatgtac ctgatttctt taaacaaatc
    26701 acagtcacat ttaacccgtg gaatgagagg cattggctca agcgtgtatt cttcgatgaa
    26761 gagacgagac gggctgacac attcgctact acaaccactt ataaatgcaa tgagtggctt
    26821 gatgaagtcg atatcaaacg ctatgaggat ttgtatcata cgaaccccag acgtgctaga
    26881 atcgtttgtg atggcgaatg gggagttgct gaaggtttaa tctacgaaaa cgtgactgtc
    26941 aaggatttca ataaagatga attactacaa gattcagcta ataaattatg tatcggtctt
    27001 gactttggtt ttactcatga tccaactgct ttgtgttgtt cgttgataaa tgacacgacg
    27061 aaagagattt atgtctttga tgaggcgtat aaagtcggat tgataaccaa agaagttgcg
    27121 aagatgataa aagacaaagg ttatcatcgc tcacaaatca ttgctgatag cgcagagtca
    27181 cggctgattg aagagctcag gtcagaacat ggcatatcta gaataaaaga gagtcggaaa
    27241 ggtaaggata gtattatggc aggcgtatcc aaattgcaag gatacgctat ttatgtgcat
    27301 ccagattgta aaaacatcat ggatgaattt tatagttact gctaccagcg agataaagaa
    27361 ggcaactggt tgaataaacc agaggataaa aacaaccact tgatggacgc tttgcgttac
    27421 agccttcaat gtatcgaagg tggaaaagca accgtccgca gacgttctga ttatggtcta
    27481 tagagaggaa agacatgtac caatatttaa cctatccacg ggatggatat gatgagggtt
    27541 ctttgaagaa agacctgatt tacaaattga taacgataca taacactgaa agctcacgct
    27601 tgaagaattt aaaaagctac tacatgggtg atcatgctat tttaaatcac aagagacgca
    27661 acgtgaacgc acccaattac aagacggtag ctaatcatgc caaggatatc gcagacacgg
    27721 ctacgggcta ttttatgggc aatcctatca agtataacaa tactgctgac ggtgatattg
    27781 atgaactact tacagccttt gatggtgctg agattgacca agtggatgcg cagaacgcac
    27841 taaatatggc tatctacggc cgtgcttacg agtacatcta tgctaaagag ggtatgactg
    27901 agttggattc aactagtatt gatccggaga atactttcat ggtctacgat gatagtattg
    27961 agcggaagcc tttgtttgcg gtctattact atgaagtaaa agacgatacg aaagacacta
    28021 ccaagcacca ggctgaggtc tttaccgaaa atctgcacta tcacatggtg ctgagaagta
    28081 cagattcagg aacaactcag agcgaggagg caacacctca caaccttggt caaatcccaa
    28141 ttatcgagta tcgcaataat cactttgcga ttggcgacta cgagcaacaa attagcttga
    28201 tagacgctta taattccttg atggggaatc gtgtcaatga taaggaacag gctgtagagt
    28261 ctatccttgt cttgtatggc acgcagttag cagacactcc agaagacgct aaggtagcaa
    28321 tgaagattct ttctgaagaa ggtcttttgg aattgccggg cgatagtgca agggctgagt
    28381 tcttgaagaa tacgctggac gaaagtgcta ctgaaatctt gcgtacagct cttaaagagg
    28441 acatctacac atttagccat gtgcctaatt tgactgatga gaatttcgca gggaatacat
    28501 caggcgtagc catggaattt aagctgatgg gccttgagat gattactaag accaaggaag
    28561 cgaactataa gcgaggattg cgtcagcgta ttgcgatttt tgctcattac ttaggcatga
    28621 agcagattgc tttagagtct cattcaatcg ttccacaatt cagtcgtggt ttgcctaaga
    28681 acttattaga aatctctcag attgtgaaca atttggaagg caaagtgacc aatagacagc
    28741 ttatttctct cttgccgttt gtggaagacc ctgacgctga gctggaagcc ttggaagaag
    28801 agaaaaagaa gaacatggaa gacatgccga tgttcaacaa agacaacacg aaacccgaag
    28861 acgaggtaga ggatgaagaa tcaggagtat tgggcgaaga ggaaagccaa tctgatttac
    28921 cagcagatgg acaaggccga aaagcaggca gaccagttcg ataaggtcta tcaggaagct
    28981 aagacttact tggataagga aatcaataag attttcgata aattccaacg tgattatggt
    29041 ctaagtcagg tagaagctag acaagtcttg aagaacatga aagacaagaa aaatctgaat
    29101 gaacttcgta aagtacttga agcgagaccg aatgacccga acatccaaag attactagct
    29161 gacttagaca gcccagctta ttctttccgc atgaagcgcc tagagcgttt gagcgacgat
    29221 ttagatcgta tgcgtgaatc tatctatcat tcggagaaga caggctcaga tgccttttat
    29281 agcgacctga tgaaggatag ttactacaag gctacctttg acctacaaca gcagacagga
    29341 ctagcatatg gcttttctgg gcttcctgag aacgagatta aacatctaca gtcttttagt
    29401 tgggtaggag atggaagtac gtactcaaca gacatctgga agaatacagg aaaacttact
    29461 tccagcataa aagatgaact cctcattagc ctcatgacag gcagagatac acgagaaact
    29521 gcacaagcaa ttgctgagag gttcaatgta ggtcagaacg atgcaaggcg tttggttcga
    29581 acagaatccg ccttttttca taaccagatg gagctactca gctatgaaga agcagacata
    29641 gaaaagtata tctttgtggc cgtcttagac aagcgtacat cacgcatttg tcaggagcat
    29701 gacaatcagg tctatgatag ggataaggct gtccctggtg tcaattgtcc gcctatgcac
    29761 ccttggtgta ggtctactac tgtcggatac gatgaggacg cagactacag caagttgaag
    29821 cgcagagcaa ggaatccaga gacaggtaaa gttgagtacg tgcctgccga tatgacttat
    29881 aaagagtggt atagcaagta tgtggatggt aatagagagt ctattaaacg taaagcgttt
    29941 gataaaacta ttaaagatgg tataatagta agtgtatcag ggactacaat tggacacact
    30001 ccgcctggca aaataggttt gcctaatagt gtagttcagc ataatgctac aaacggagat
    30061 gtccttggta gaacttacta tgatgctaga ggttttaaaa cgaaagatgt tcattttaca
    30121 aaccataaac aaccggcacg tcatccttat ggaaaaatcg gagaacatgc tcatgatttt
    30181 gtatttgatg atgaaggtaa gttcgttagt aggagtacta gggaattaac agacgatgaa
    30241 agaaaggaga atcaagatat attatggcga tattagatga tttacaagcg ttatatgata
    30301 atggatggga cgcttctttt aattataatg gtcaagtatg tggcattttc cctaattcta
    30361 tttatgatgt tgttgttatt attgcggacg acgaatatag agcatcttct tttgacgatt
    30421 tgatttcttt acagattgaa gggaaaactt taccggaaat catgaacgaa gttgaagtac
    30481 aatatggcta aagcacctag agagatctaa gtgctttttt agtacccaga aaggagacta
    30541 tccgtacgat tttcttgatt gtgaatttga agtaaaaaga atttcagtga tagcttgcga
    30601 tactatcctt atagaagcct aaaagaaagg aacagaaaaa tggaagaatg gaaagaaaga
    30661 tttaaaaaag aatactacga attgaaagaa cgattccaga agttagatat gatgattggg
    30721 aaatacgaaa aagggcaact agagtttgaa tctaaatgtc cgattgattc gttaaaaggt
    30781 cagcgttcaa ccatgtggaa ttatttaaga attctagaac aacgtgcaaa aattgaagaa
    30841 attaaactat aaaaattaac cgcatcgaaa tcgatgcggt tttcctatgc cctaaccgta
    30901 tggaatcccg tacggttttt atattgtcca aactgtaccg atgacaataa aagctgtgct
    30961 gttccgtcgc cggacgtaaa acgagattat cgagtggcga cgtaatcgct ggaggacaat
    31021 tatgtcagaa gaaatcaatg caactgtatc tactgaatca actgagactg tcgacactca
    31081 aggaaatgtt gattcagtgc aggaagaaaa gcacgaacga actttcactc gtgctgaaat
    31141 cggtaagatg ctatctgccg aacgctctaa atgggaagct gagcaagaag ccaaggaaaa
    31201 cgaagctaag aaacttgcca agatgaacgc tgacgagaaa caaaaatatc agttggatca
    31261 gcgtgagcaa gaactagctg accgtgagaa ggctattgct cgcaaggaat tgaccgcaga
    31321 agctaaagca atgctaagtg aacgtgactt acctgttgag ttagtaaatg tagttgattt
    31381 gacaagcgca gagacggtat cgcagtctgt cgctgtattg cagaaatcat gggagcaagc
    31441 cgtgcaaaaa ggcgttcaag aaaaactaaa aggcggagct ccaatgaaac aagcgccagt
    31501 cgatagtgac ggtatcacaa aagaagaatt tgctcgtatg ggttatcaga gtcgaaatga
    31561 gctctatcaa aagaacccag agctttataa gaaattgaaa ggataataga aaatgacagc
    31621 aggacaaact aaattagcca ctatggttaa tccagaagta atggcggata tggtagccgc
    31681 taaattacct aaattgatta aatttacacc gctagcgtat gtagagacaa agcttgaagg
    31741 tcaaccaggt agcactttaa cagtgccagc atgggagtat gcaggagacg ctactgaaat
    31801 tgaagaaggc caagcaatta cgccagacca attgactact aaaaagacta ctatgaccat
    31861 caaaaaagca ggtaaaggtt atgaaattac cgatgagtct cttttgtcag gtcttggtga
    31921 cccactaggt caagcgactt accagcttgg tttagctatt gccaacaaga tcgataatga
    31981 tttggtagcg gtagctaaaa ctgcaacaca acatattaca gaaactccaa caactcttga
    32041 ggcaatcgat aaagctctag atatctttga ggacgaagaa gatgcacagt atgttgctat
    32101 catcaaccct aaagatgcta ctaagctaaa aactgcagta gcaaaagaat ggattaaagg
    32161 ttcagagctt ggagcaaata tggttgtttc tggaaccttc ggtgaagttg atggtgtgca
    32221 aatcgtgcgc tctaaaaaag ttgatgaagg taaaggcttc cttgttaaag tgtcaccaag
    32281 tcaaactcag acagacgacg ctaacaaata tggagctttt gttatcttgc ttaaacgtga
    32341 tgtggctatc gaaacagacc gcgatatctt gaagaagact accgtaatca caggtgatga
    32401 acactacggc gtttaccttt acgaccctac acgagttgta aaattcggtg gcgcgtaaga
    32461 ggtgacgata tgagtttatt gctacgacgt cattatattc aagaagagca ggttaaccag
    32521 tattctgatt tagagaataa aactctagaa gagttgaagg atctagcgaa agaagcaggt
    32581 gtagcaggcg cttataagtt gacaaaagcc gaaattgtag aagttttgga ggaactaaaa
    32641 agtgaaattt aaaatcaaac aagatttcta tgattgggaa tcaaatgtga aacgactggc
    32701 aggagaggaa cttgagatta ctgaggagcg ctatgctgag ctggctgaca atattgccag
    32761 caacggtgtc actatctcag acgttcttga gaaaatcctc cctgaacctg agttcttaga
    32821 agaggattga tatgtctata gagttgctga agaaattaac aggcgaagaa gatactcagc
    32881 ttctcatgtt gctccaaacg agggctacaa atcttatctt gtcagagact aatcgcacat
    32941 ctttgacacc tgctttaagt cttttaatac ctgaggttgc tatcgaactc cacaaccgct
    33001 caggagcgga aggagagcat tctagaaccg agggtggtat agcagtagtc tacggagaaa
    33061 acggcctgtc tacggatctt ctacagcgaa tacgcatgca caggctagca agggtggcag
    33121 gtcatgtttt tgaagcagag tagactgaaa ccttatccaa tgcgacggtt tgaaaagact
    33181 gtcactgagg aaggtgtcgc gaaagaaggg tatgccaagg aagctgagac agtccgcctt
    33241 gaattgtggc cagctagtag caagctacaa tctgaattgt atggcgagcg tgtcaatgat
    33301 attttgaacg caaatgccaa caagtcagct actatcaaag taaaagatgg tgtgtgtatc
    33361 gatagtcaga cggaagtgac tcatagggtt atttctaaaa aggtctacac acatcatcaa
    33421 gttttggagt tagagcgtgt cagggctact aggggcagat aggcttatag ctaaatgtag
    33481 acgattggct agtaaaaaaa ctggcgagga tatcgtctta cgtgcggtgc acaatgctac
    33541 tataaaggtt gtccaagcag atgcaagaag actcgcacca gcgagagatg gagagcttat
    33601 aactagtatc aaaactaggg caaaaatgga cggagataag gctataggcg aagtttacac
    33661 caaccttaaa tacgctcctt atgttgagtt tggaacggga ccaataggac aagctagcca
    33721 ttctggtatt tctccagagg tcagcgtgac ttacaagtct agtccgtggt atgtacatga
    33781 agaccaaatc aatgtaggac cgtaccactt tcaaaaaatc ggggagttct acaagatgta
    33841 tggtcaacct gcccagcctt atctttatcc agctttgaga gacaatcaag agcgtgtgtc
    33901 taagaatatt tcgaattatg tccgtagaaa gataagagaa caaataaaat gattaatatc
    33961 aagcctgtta tttataaaga attgcaaaag gttgcagata atgtgaccga tacttatcct
    34021 agcgattggg agactttccc agtcgttatt tttttggaag aacaaaacaa gccgggtgat
    34081 tggtttgatg accaggaaca aaaatcctct atccgctaca aggtggatat ctttgatgat
    34141 actagcacta gtgagttagc tgttaaaatc aatcagattt ttgagtcttt aggtttgcga
    34201 agaactgact gccaagacgt gccagacccg tctcatttga gacataaggt catgcgtttt
    34261 gaaggtatcg tcgacttaca ctcagagctt gtttttcaat ttagaatgga gaattaaaca
    34321 tgttagcaaa tggaattacg ctttcttatg gcgaaacaaa agatagctat actaaacttg
    34381 ttggattgaa agaagtacca gagtttggta ttgaactcga aaaagtagaa aatactactc
    34441 ttgaagatac ggtgaagaag tacgagtttg gtattgggga cataggagaa cttgagtaca
    34501 agttctctta taataattca agcgcaactg ctccttatcg tgtattgcgt aaggcagcag
    34561 acgacaagaa gaaactctac tttgaacaag cttatccaga cggtactaag gtcatttttg
    34621 aaggccaagt atctgttaag cttggcggtg gcggtgtcaa tgccgttatc gatttcacac
    34681 ttaagattgc cttgcagtct aatcttacat ttactgatgg tattggaggt taattaaatg
    34741 gcgttaaaat acacaacttg gaaagttact gacgaaaaag agttgaagct acgtttgaca
    34801 tctcatcaag ctgcaactgt ggaagaaaaa atcggcatga acttgctgaa gattttcatg
    34861 cctgaagctg gcgaagagtt cactttaccg cctttgaaag ttatgttgtt gttagttcac
    34921 ggagccttgc agcagtatga acatgggtat tctcttgagg atgtctatga tttatacgat
    34981 gaatacgtgg acaatggcgg agaccaaaca accttcatga cagaggtgtt gatgccactc
    35041 tttgaagtat cgggttttac tccacgagga agcaaggaca agaaaacttc caagaagaaa
    35101 atgacagtag acaagtaatc ttaacggtaa ctcagattat tgagaggctt tatcctatgt
    35161 ttttggacat cgagggcaag cctcttgatt tttgggattt gacggtactt gaaatcagag
    35221 aaatgattga aagctataac cgtgtcaaaa tccaagagcg taaagaaaag attattgact
    35281 catacagact ttcgcagatg atatccaacc acgtttcttt attgttatcc aaagatgcca
    35341 aggcctttga gttctgggaa tatgcgcctg agttgtttgt agaagaacaa caagcagtag
    35401 aacaggaacg acagaaacaa gcacttttgt tgcataagga acggatgcgt gaatttgcag
    35461 agagacataa tcgaaaaagg aaggaggaag taaatggcaa ctcttgatga attgaaagtc
    35521 atgattgacg ctgagatagc gcctttcagg aagaagatga aagaagtcga gaatcaggtc
    35581 aaaggaacat ctgaccaagt gaaaaatgct actgccaaag ttcgtgaaca gtcgagctca
    35641 atcggtagtg cgtttggcaa gctggctaag ttcgctggtt ttgcaatcct tggtaagaaa
    35701 ttacttgatg ttgggatgta ttcaacgcag acggctcttg aagtatcagc gtctatgaac
    35761 caaatcaagc gacagatggg cgagagttcg caatctttct taaaatgggt taacgataat
    35821 gccaacgcta tgaatatggg tgtgggtgag gctaccaact acggtgcagt ctactcaaac
    35881 ttattttctg gatttatcaa agataccaac aagctaagcg cctataccgc taagatgttg
    35941 cagacatcgg cagttgttgc tgaaggttca gggcgcacga ttacagacgt tatggagcgg
    36001 attcgctcag gtttactagg gaacaccgaa gcgattgagg acctaggaat caacgtcaac
    36061 gtggctatga ttgagtccac tgaagccttt aagaagttcg caaacggaca gagctggcaa
    36121 cagttggatt accaaaccca gcaacaaatc cgccttatgg ctattctgga acaggctaca
    36181 gccaagtatg gggatacctt gtctaattct gtaaatggtc gtatcagcct atttaagtcg
    36241 ctgatgaagg acgcagcatt gaaccttggt aactctatgt taccgattat caatgccatt
    36301 atgcctgtct tgaactcttt tgctatggtc ttaaagaacg ttactgctaa actcgctgag
    36361 tttatcgctt tgatgttcaa caagaaagca acagtgaaag atggtgttgg tggagcagtt
    36421 ggagacatgg gtaacgccat gaaggatgct gcaggcggag caggagacct tgctgacgca
    36481 gtagacgacg ctggagattc agcaggagga cttgctgaca atcttggaga ctccgccaaa
    36541 aacgctaaga aggccgctaa agagttgcta ggtcttttgg gatttgatga gattaacatc
    36601 ttgcaaaaac caaaagatga cgacgcaggc gggtctggag gcggtggcaa aggtggtaaa
    36661 ggaaagggag gcggtggcgg acctttcaaa gacatcttgc cagaagtcga gttgaccgac
    36721 atggacaaca aattcaagag catttttgat ggtcttggag ataagctcaa agggttgttt
    36781 gacctcttca agaaaggttt tgatgcagca tttagaccag aaggtataga acgcattaag
    36841 actgccttag accaaatagc taagacaatg ggagaaatcg ccactgaccc aagggttgtg
    36901 aatgccttta accgaatggc tgagaaaatt gcttatgctt tagggcaagt gacaggctca
    36961 ataacaacta tcgggctagg tatcggtgtt ttccttgccg aaagtattgc aaatggcctt
    37021 ggaaggcaaa aagaacgcat taccagggcg ctagtcgctt tgtttgataa tattggtaac
    37081 atttccgagg cagtaggaaa catcgctcag gacttttcta gtactttcta cgacgtcatt
    37141 acctcaactg gtgcggttcg tatcggtagc gctattgtgt caactctgtt gagtttgaca
    37201 tctaccattg ttgaagttgg tagtaaatta gcaggaagtt tgtttaaagg ttttgaaaaa
    37261 gtcgttgtga caagcgctcc taaaatttca tcagtcttcc aaagtttatt agatactgtt
    37321 gcgcctgtat ttgagagcat tgaaaggtct gttaacaaat ttggcgatgg cttaagtcgt
    37381 gtttatgatg aacatgtagc ccctgctatt aactctattg ctaatgcttt taacggactg
    37441 attgatatca tacaaatcct ctgggagaat tcttggcaac cttttgctga gtttttatca
    37501 ggagtattcg gtgttagtat tgaaggaatt tcagatttat taggaggtgg ccttttagcc
    37561 actttgggac tattggcgga tgctattaag ttagtggcag atggtttcac cgttttttct
    37621 gactggtgta aagaaaacaa agaacctatc ttggctttga taacaacttg gcaaacgatt
    37681 aatttcttat catgggctga acaagccggg ggacttgcag gagcattcag cttgttaggt
    37741 agtaaggtct ctttgattgt tggagggatt aagaatctag gtcttgctat taaagcattg
    37801 acatttgata agttggtcag ttttggtgaa acaatctatt tgaacacctt atatgcaaaa
    37861 gattttgtgg tcaattcagg taaaacaatt gcacagctag gaaaaactgc tttagaactt
    37921 ggtaaatcag ctctagcatg gactgctcat gcagcgaaaa tgggattagc aaccgcggcg
    37981 gaatttgcac attctgttgc agcaggagtc gctacagctg caacatgggc ttttaatgca
    38041 gcgttagcag ttttgacaag tccaataaca tggattattg cagcaatcgc agctttgatt
    38101 gctatcggtg tcttgctcta ccaaaactgg gacactgttg ttgagtttgc taaaactgca
    38161 tggcaaggac tatgtgattt tattagtggt atttgtcgag ctattggcga atttttcagt
    38221 ggtctatgga caaaactaca agaaatcttt gagccgatag gtcaatggtt tggcgagaag
    38281 ttccagcaag catgggatgc cattgtcaac atcttctctg gtatcggaga gtggttctct
    38341 ggtgtattcc aaggtgcatg ggacgctatc gttaatatct tcactccaat cggctcatgg
    38401 tttggacaac gttgggcaga tgtgactagt gctttggcta atatcggggc atggtttact
    38461 gacatattcc aaaaagcatg gactggtcta acaaacatct ttagcaaact aggtttatgg
    38521 tttggcgaga gatgggcaga tgttacaagt gttcttgcga atgtatcttc ttggtttggg
    38581 aatatgttta ctagtgctta taatgcagtc aagaacgcgt ttagttcaat tggtggcttc
    38641 ttcagcggtg tatggtcaac ggttcaaagc atatttgtca atgctggaca aaaggttggt
    38701 agcgctgtag gtggagcgtt taagagtgcg gtcaatgcgg ttcttggaac gattgaaaat
    38761 gtagtcaatg acttcatcgg aatgattaat ggagttttag gcgttgtcag aaacttacct
    38821 ggtctaggat gggttggtag tgtaagcaca gttagcctcc ctcgtcttgc ccgtggtggt
    38881 atcgtcgata gtccaacaat cgccatgatt ggtgaagctg gtaaagaggc ggtcgtacca
    38941 cttgaaaata caggatttat ccaaacactt ggacgagtag tcagcagtgc ggtagtaaat
    39001 gccatggctg gtattagtcc acaaggtggt ttttctagcg acggcgacat cgttattcaa
    39061 atcgcaggcc atgagttcgg acgggtagct atccaagaaa tcaacaagga acatgaacga
    39121 gcaggtcaaa ccttgctcaa gatttaggag gttaaatggc acaattgaca atcaatgggg
    39181 tggctgtgaa gcctcccaaa tcttttcaag tcggtattca agatatcgat ggagagacag
    39241 ggcgtaatgc caatggcgac atggtgcgtg accgtatcac gaccaaacgc aaactagact
    39301 gtgaatgggg tatgatgact cagggagaaa taagtcagct tttacatgct gtatcatcta
    39361 aattttttga ggtatcttat ccagacccca tggatggcca agtcacaaag actttctatg
    39421 tcggtgatag gacagctcct agctatacct ttactgagaa gcttaaacct tggtctggcg
    39481 ctaaatttaa tctggtagag aggtaagaaa atggacgctt taactagacg acaatttgac
    39541 agagccatgt ttgccaagga aaggacgctg gctattcgtg ttggtgaata tgcttcacgg
    39601 gatatcaaag aggctagttt tgagtatggc tacatcaagg gcgatactta taagcctggt
    39661 ggaacctgcg ctggtagcgg taaaattacc tttaccagta tcattaccac gttcaataag
    39721 ctggataccc tgcaccctga gattggtcta ctggttgggg atacctacca gtgggtcaag
    39781 atgggggaat acttcatcaa cgatattgag attgaccgaa accgcaacac aaccacactt
    39841 gaacttatgg acggtatgtt taagctcaat cgtgagtacg tgacggattt gcatttccca
    39901 gctgaagtac gagaggttat tcaggaaatc tgcctgaaaa caggcattga gttagcgaat
    39961 gactatttcg gaatcagcgc tatgcgttac catatcgagc aagttcctga aggtaagaaa
    40021 ctttcgttca gggatatgct gagcgctatg actcagatga ttgggatgtc ttgcttcttc
    40081 aaccgagaag gaaagatgga aatccgtgat ttgaccgagt ccaacatcac gattaacgct
    40141 gacagttact tcttgcatgg attgaccaag agtgaaatcg agtatcagat agctggtatc
    40201 acttgtaaga cggataagaa gtctctgacg gtcggtatga caacaggtcg gtctttggaa
    40261 cttgataatg tcttcataac ccagagcgct ttaaatgact tgtattacaa actgaaaaac
    40321 ctaacttact atccgtataa tctcaactac caaggacatt tgttacttga ggttgggcag
    40381 tgggtaacca ttcagaccaa caagaaagag acttttaaag ttcctgtctt aagtcagagc
    40441 tttatcttta aaggtggtct gagaggtcgt atcagtgcag atagtaaggc tggaaacgat
    40501 acccagtatt cttacgaggg tacgattacc aagcagatta agcaacaaga tggctttgaa
    40561 gcgaaaatcc aagcgcagat tgaagcagca gataaagatt ttgaccaaaa ggtcgacaaa
    40621 atcaaaaaag actttaacga tcaagtagaa ctggccaaag ccagagctga agaagtcaag
    40681 agagaactgt ctgacactat caatcagcgc tttaatagct ttgacaacgg gccattgaaa
    40741 gaagctaagc gcaaggctga ggaagctttg cgaaatgctg gcgcaagtag ttctcttgct
    40801 caggaatcca agcggattgg gctggattct gttgctagac ttgaagcgtt taagtcgcag
    40861 actacgagcg cacaaacggc tctgtc
//
LOCUS       DAYYYC010000014        40117 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.014, whole genome shotgun sequence.
ACCESSION   DAYYYC010000014 DAYYYC010000000
VERSION     DAYYYC010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40117
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.014"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(<1..66)
                     /locus_tag="ACHBV5_000775"
     CDS             complement(<1..66)
                     /locus_tag="ACHBV5_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HFM9966614.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRI"
     gene            complement(193..720)
                     /locus_tag="ACHBV5_000776"
     CDS             complement(193..720)
                     /locus_tag="ACHBV5_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HFM9966615.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            complement(906..1079)
                     /locus_tag="ACHBV5_000777"
     CDS             complement(906..1079)
                     /locus_tag="ACHBV5_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966616.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            complement(1153..2793)
                     /gene="mobQ"
                     /locus_tag="ACHBV5_000778"
                     /pseudo
     CDS             complement(1153..2793)
                     /gene="mobQ"
                     /locus_tag="ACHBV5_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
     gene            complement(3103..3420)
                     /locus_tag="ACHBV5_000779"
     CDS             complement(3103..3420)
                     /locus_tag="ACHBV5_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HFM9966617.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            complement(3476..3955)
                     /locus_tag="ACHBV5_000780"
     CDS             complement(3476..3955)
                     /locus_tag="ACHBV5_000780"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFM9966618.1"
                     /translation="MFITEKKGKSSQVPTGSSIPKRYLLDGKTPRISATNIDNGILGY
                     YEDIDDKNYRVFENFISVSFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSI
                     IRQALKNTEYKDQISSTVLPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            complement(3954..4138)
                     /locus_tag="ACHBV5_000781"
                     /pseudo
     CDS             complement(3954..4138)
                     /locus_tag="ACHBV5_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612340.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(4289..5083)
                     /locus_tag="ACHBV5_000782"
     CDS             complement(4289..5083)
                     /locus_tag="ACHBV5_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966619.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKYHVSS"
     gene            complement(5083..6090)
                     /locus_tag="ACHBV5_000783"
     CDS             complement(5083..6090)
                     /locus_tag="ACHBV5_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HFM9966620.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFVLLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(6090..7097)
                     /locus_tag="ACHBV5_000784"
     CDS             complement(6090..7097)
                     /locus_tag="ACHBV5_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFM9966621.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(7087..8112)
                     /locus_tag="ACHBV5_000785"
     CDS             complement(7087..8112)
                     /locus_tag="ACHBV5_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HFM9966622.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(8505..8723)
                     /locus_tag="ACHBV5_000786"
     CDS             complement(8505..8723)
                     /locus_tag="ACHBV5_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM9966623.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(8969..9247)
                     /locus_tag="ACHBV5_000787"
     CDS             complement(8969..9247)
                     /locus_tag="ACHBV5_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966624.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWYAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(9461..11092)
                     /gene="rlmD"
                     /locus_tag="ACHBV5_000788"
     CDS             complement(9461..11092)
                     /gene="rlmD"
                     /locus_tag="ACHBV5_000788"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFM9966625.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKIFMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(11166..12140)
                     /locus_tag="ACHBV5_000789"
     CDS             complement(11166..12140)
                     /locus_tag="ACHBV5_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HFM9966626.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(12214..12828)
                     /gene="pmp23"
                     /locus_tag="ACHBV5_000790"
     CDS             complement(12214..12828)
                     /gene="pmp23"
                     /locus_tag="ACHBV5_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HFM9966627.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(12828..13802)
                     /locus_tag="ACHBV5_000791"
     CDS             complement(12828..13802)
                     /locus_tag="ACHBV5_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFM9966628.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(13810..15066)
                     /gene="glyA"
                     /locus_tag="ACHBV5_000792"
     CDS             complement(13810..15066)
                     /gene="glyA"
                     /locus_tag="ACHBV5_000792"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFM9966629.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(15128..15559)
                     /locus_tag="ACHBV5_000793"
     CDS             complement(15128..15559)
                     /locus_tag="ACHBV5_000793"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9966630.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSLEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGEGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(15561..16163)
                     /locus_tag="ACHBV5_000794"
     CDS             complement(15561..16163)
                     /locus_tag="ACHBV5_000794"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFM9966631.1"
                     /translation="MIDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(16147..16986)
                     /gene="prmC"
                     /locus_tag="ACHBV5_000795"
     CDS             complement(16147..16986)
                     /gene="prmC"
                     /locus_tag="ACHBV5_000795"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFM9966632.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASNQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     RQD"
     gene            complement(16986..18065)
                     /gene="prfA"
                     /locus_tag="ACHBV5_000796"
     CDS             complement(16986..18065)
                     /gene="prfA"
                     /locus_tag="ACHBV5_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFM9966633.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLKELNK"
     gene            complement(18075..18554)
                     /locus_tag="ACHBV5_000797"
     CDS             complement(18075..18554)
                     /locus_tag="ACHBV5_000797"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9966634.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIVISSGNYLLFCFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(18544..19143)
                     /locus_tag="ACHBV5_000798"
     CDS             complement(18544..19143)
                     /locus_tag="ACHBV5_000798"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFM9966635.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPIMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            19267..19449
                     /locus_tag="ACHBV5_000799"
     CDS             19267..19449
                     /locus_tag="ACHBV5_000799"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HFM9966636.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            19586..20959
                     /gene="mnmE"
                     /locus_tag="ACHBV5_000800"
     CDS             19586..20959
                     /gene="mnmE"
                     /locus_tag="ACHBV5_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFM9966637.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(21006..21941)
                     /gene="dapA"
                     /locus_tag="ACHBV5_000801"
     CDS             complement(21006..21941)
                     /gene="dapA"
                     /locus_tag="ACHBV5_000801"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFM9966638.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(21997..23073)
                     /locus_tag="ACHBV5_000802"
     CDS             complement(21997..23073)
                     /locus_tag="ACHBV5_000802"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFM9966639.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(23415..23487)
                     /locus_tag="ACHBV5_000803"
     tRNA            complement(23415..23487)
                     /locus_tag="ACHBV5_000803"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23452..23454),aa:Thr,seq:ggt)
     gene            complement(23587..24096)
                     /locus_tag="ACHBV5_000804"
     CDS             complement(23587..24096)
                     /locus_tag="ACHBV5_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFM9966640.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIQKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(24094..24190)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            24219..24650
                     /locus_tag="ACHBV5_000805"
     CDS             24219..24650
                     /locus_tag="ACHBV5_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFM9966641.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            24732..25109
                     /gene="mscL"
                     /locus_tag="ACHBV5_000806"
     CDS             24732..25109
                     /gene="mscL"
                     /locus_tag="ACHBV5_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFM9966642.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(25151..26245)
                     /gene="hemH"
                     /locus_tag="ACHBV5_000807"
     CDS             complement(25151..26245)
                     /gene="hemH"
                     /locus_tag="ACHBV5_000807"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HFM9966643.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(26323..27198)
                     /gene="srtG2"
                     /locus_tag="ACHBV5_000808"
     CDS             complement(26323..27198)
                     /gene="srtG2"
                     /locus_tag="ACHBV5_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
                     /protein_id="HFM9966644.1"
                     /translation="MTVQKRARFKNVFLVFFCVFVALFSWQRVVEASDYDHYNPIEKD
                     ASSTGFETLQHLNKDVCGWISLDGTKVDYPLLQSQDNVKYLDRNAFGDYTIMGSIFLD
                     YRFNPNFTDFNTIIYGHSMASGAMFGEIKKFADKEFFDQHRYGSIYYNGRERGLEIFG
                     ILEVDAYDTEIYRTLSSKDEEHQAYYQYLLSKAKYKRDVSLTSTDKIVLLSTCFLNIT
                     NGRHILLAKITDAPVKVAQDESGEAVGTRYFDHGIPSHWIYILAFLLLIIVLLLLVLI
                     ILIIRRDKKTKEQKK"
     gene            complement(27276..28274)
                     /gene="srtG1"
                     /locus_tag="ACHBV5_000809"
     CDS             complement(27276..28274)
                     /gene="srtG1"
                     /locus_tag="ACHBV5_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HFM9966645.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(28292..29488)
                     /gene="pitB"
                     /locus_tag="ACHBV5_000810"
     CDS             complement(28292..29488)
                     /gene="pitB"
                     /locus_tag="ACHBV5_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HFM9966646.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVEPSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(29533..30084)
                     /gene="sipA"
                     /locus_tag="ACHBV5_000811"
     CDS             complement(29533..30084)
                     /gene="sipA"
                     /locus_tag="ACHBV5_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HFM9966647.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLAIL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(30084..32669)
                     /gene="pitA"
                     /locus_tag="ACHBV5_000812"
                     /pseudo
     CDS             complement(30084..32669)
                     /gene="pitA"
                     /locus_tag="ACHBV5_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516426.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus tip adhesin PitA"
     gene            33028..34251
                     /gene="pepT"
                     /locus_tag="ACHBV5_000813"
     CDS             33028..34251
                     /gene="pepT"
                     /locus_tag="ACHBV5_000813"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFM9966648.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(34287..34940)
                     /locus_tag="ACHBV5_000814"
                     /pseudo
     CDS             complement(34287..34940)
                     /locus_tag="ACHBV5_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
     gene            34938..35102
                     /locus_tag="ACHBV5_000815"
                     /pseudo
     CDS             34938..35102
                     /locus_tag="ACHBV5_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(35373..36386)
                     /locus_tag="ACHBV5_000816"
                     /pseudo
     CDS             complement(35373..36386)
                     /locus_tag="ACHBV5_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(36612..39731)
                     /gene="phtE"
                     /locus_tag="ACHBV5_000817"
     CDS             complement(36612..39731)
                     /gene="phtE"
                     /locus_tag="ACHBV5_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HFM9966649.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQISQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLKEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT        11396 a         7859 c         6901 g        13961 t
ORIGIN      
        1 tatccttttg tctgtgaaaa attcttcttt taattttatc caatagtatc ttttgtttgt
       61 tgccatatct gctcctttct tgattttcga taatcgaaat tcttgatttc cgattttcgg
      121 aattctggac ttctgttttt cggaagtctt gttattatgg ttatttaagg gtgtaacttt
      181 tcgttactcc ctttagattt ctctggtcat atcttttttg tttggtttta ctttttcttt
      241 tactttcctt tttccttttt cttttgtctt atctttgttt ttggataggt ctttgtattt
      301 ctttatttgt tttaggatac tttctttttc ttttttattt tccttggcta tgacttgctt
      361 aaaggcatat tccattactt ttatgtcttt ggcttggaag aatatttcat agtttttgct
      421 ttctttgttt ttcattactg agaaacttac tccaagtttg tttagttctt tttttaagtc
      481 tttgaggtcg atttgatcta tgcttatatt ttctagttgt cctttcttgt agagatcttt
      541 tattttcatt tcatcgccca taagactttt taagtttcca tttgcttttt ctaaagtttc
      601 attcatcttt tttcttattt ctttttctaa attgattgat tcttttgttg cctttattgt
      661 gtatgatatt atggtttgtg ctgcttgacc tgcttccttg cttatttctt cgtttatcat
      721 gcttttctct cctttgtttg aattaaaaaa gggaagtata ggttttaatt tttctatact
      781 tccctttgct tgtttttatt ttattgttct tggtggtgga atactttatt ttgatgtttt
      841 tatatatttc ttaggtcttt gtacctttta tacttttaaa aatagcttac actacctttc
      901 cacctttaat agtttatgtg tgttcttttg tctgatagat agtttttcat gttggaatat
      961 ataatctgta tttcttcatt gttcattgct tttatttctt ctgtgctttt ataggttttg
     1021 tatgttccat cttcatttgc ttttatgagt tcatctatta gctcttgcct tttattcatc
     1081 tctattacct cctagatctg actttagttg tttggtcata ttatagcttg gataagatat
     1141 ttttaccagg tcttatcttt cttgatccat tttcttgttt ttcatcattt ctctgtattc
     1201 attatcttta ttgacttggt cttggaactt tttaatctgt gctattacac ttggtttttc
     1261 tccctgtttt attagcttat ctatttctat ggataaatct ataccaagtt ctttgtttac
     1321 aaaatctact gaatatttta tatgattaat ttcctggtat tcatctttta tcttgtcttt
     1381 ttctttattt atttcttcaa gattttacat taaaagaatt ttttcttcat tccacttttt
     1441 aggacttagt ttttccttat ctgataggag tttttttaat ttcccactta ctactttata
     1501 ttggtctata tctttcttat gtttgttata aaatgcttct tttgtgaata tatttttctt
     1561 ttgatattct tcataaactt cttttttggc tttgtagatt tcatagtata gaattttctt
     1621 ttctacatct tccatttctt tatggattgt ctttgctttt ttatttagcc tataactatt
     1681 agactttaaa gtttctattt ttgtttgtaa ctgacctatg gtttctatgt tgttttttct
     1741 taaataacta tatgcacttg ttagcttttt gaagtcatat ttttctttat tagtttttgc
     1801 atatcctttt agatatttac ttttttcttt ttgaatttct gaataagtta atagataatt
     1861 tgttagatta aaaagtttag ggttgtctat taccttatct ctttcgatat ccttaaattt
     1921 ttcataagca gtagataagt tatctaataa atttcctatc caacccttta atgtttttat
     1981 ctcttctttt attgttttta caagttgatt atattttctt atttctctat tatagtttcc
     2041 cttgtcagtt tctattccct ttctttccat tgcacttgct gctgatccta aatggattgt
     2101 cggtagataa tctgaatttt gtcttttaaa actcctatgg tctactcttt tttctgctcc
     2161 tgctctttct aaatatttgt tacaaagatc tgaaaaattt tctctccatt gttctacatt
     2221 gcctgtatcg ttccaggttg ttagttctac ttttcttgtc tttggttttc catttttgtt
     2281 taatactttt tctccttttt catctaggat atattctttt tttgacttgg ctaagaactc
     2341 tcctttttcg tttattggtc gcattatggt cattatatga caatggatat ttccattttt
     2401 atcttgactc tcatcatgaa ttgcataatc tactatcatt ccttgtgatg ttaaattttc
     2461 ttttatatat ctttcaacca ggtttttatt ttcacttaaa gataactctt ttggtagtcc
     2521 tattatgaat tgtcttgcta gttgtgcatt agaatttttt tctgccattt ctactttatt
     2581 ccataaggta gacctatcat taaattcttt tggtatatga tcaggcaata ttatattttt
     2641 tactaatatt ttttcttttc ttgtgtagtc atgggttact ccgtcccatt cattttttat
     2701 tttttctcca cttatatatg ctgcacttgc tactgcactt ttgccttttc ctcttgatat
     2761 tatgtttact gaaaaatgaa aactgtctgc catttttatc acttcctttc tttgttgttt
     2821 taggtggagg cttaatagtt tttttatatc ctctttgtga atgagcgttt tgaaatgata
     2881 gaataaaaaa agccgactac tgaattaatt tttgttgttt cagtatgtcg gcttaattgt
     2941 tactttcatt tcaaatttta aaagtcaagg gcgagcctta gcgagtttat ttacccttga
     3001 cttttaaaaa gcgaatggtt gttgctccct gcaagggttt gactccgcag gacgcaagca
     3061 ccctttaggg tgtataattg cgcccttgta accaagggac aattatgtta tttcatcttt
     3121 agatgatttt tctacattat catctattct ttcttctaaa atttccatta tgtttaatct
     3181 tatttcttca tcatttaacg tttttattaa cttataaaat tcatcttttg ttaaatcaat
     3241 actttcttca aaaatacttt caaacactgc acctttttct ataagtcttt tgtttcttgc
     3301 ttttctttct tgttcattaa gttttttctt caactgtctt ttttgatttt gtaattgctt
     3361 aatgctttct tctttctttt caatctgttc ttcaatactt aatcttttac ttgccatcat
     3421 gtatcctttc ttaaaataaa aaacgactag atttttattt ctaatcgttc ttattttaaa
     3481 tattataatt tgctatattg cattttaatt ttaagtcttc tatatatctt tccatgtaat
     3541 tccaatctgg agtacctcta ctgtctatcg gtaatttaat tttgatatct ggcaatactg
     3601 tgctagatat ttgatcttta tattcagtat tttttaaagc ttgcctaata attgaagtta
     3661 aatagaatgc tacttcttta ttcaattctt tattttttaa ttttaaacaa tgaattttca
     3721 tatctaggct tgctttatat ttatgataaa agactgctcc taaaaatgaa acagatataa
     3781 aattttcaaa aactctataa tttttatcat ctatatcttc gtagtaacct aagataccat
     3841 tgtcaatatt tgtagcacta attctaggag tttttccatc gagtaaatat ctttttggaa
     3901 tagatgagcc tgttggtact tgactcgatt tccccttttt ttcggtaata aatatttctt
     3961 tttattttgt tgtctgatat ttttcctacc tgtcctttgt aggatgagta ttttctagat
     4021 tttcttgaat aactttttac ttgaagtttt agcttttgaa ctagtcgttg tactttcttt
     4081 ttgtttatta tcagtcctga tctttttaat attgctgtta ttctctatat cctatttttc
     4141 attcatgata ttcttttact aattttatct taaattctgt gctgtatttg ccattaaaaa
     4201 actgacctcc tttagttagt tttttggcct aacttttgag ggtcagttca aaatttgcga
     4261 cttttaaatg aattccaata ttcaattatt aagagctaac atggtacttg ccaataggaa
     4321 tcattagagg cgaattggaa atagggtcac gtataatttt tgcttcaaga ttaaagatat
     4381 ctttaactag tttatcattt agtatatctt caggctttcc ctctgcaaca agtttacctt
     4441 ctttaattgc aaataggtaa tcagcgtatc ttgctgttag atttatatcg tgcaaaatca
     4501 tgcaaatggt tgtcttatat ttttggttta gatcagtcaa gaggtctaat agttctattt
     4561 gatatgagat atccaagtaa gtagttggct catctaaaag taggatactt gtatcttggg
     4621 ctagggctag agctatccat actctttgcc tttgaccccc agaaagttct tcaactaggt
     4681 tatttgctag atcttcaaca ttggccttaa ccattgatct gtttattatt tcaaggtcat
     4741 cttttccaag actcttaaaa ggctttctgt aggggaaacg accacggctt acaagatcag
     4801 ctactgttat tgattcaggg attattggag attgaggtaa tatagctatg tgttttgcta
     4861 aatctttttc tttataagaa ttaattgatt tattatcaag caatacttct ccctctaatg
     4921 gctttataag tcgagacaag gttttaatga gtgttgattt cccacaacca tttgacccaa
     4981 taataactga tattttttct tcaggtattt ttatatttat attttccaag attatttttt
     5041 catcataacc gcaggtaaga ttatttgacc acagaccttt cattatatat tcctcctgtt
     5101 catttttatt agtaaatata ttaagtatgg tgaacctaac aagccagtta caacacctac
     5161 tggatatcta gctggtaaaa tattttgaga gaatatgtct gataacaaaa ctagtaaaat
     5221 tccaaccaat ccagctaata ttgggcttct tttcttgcca atatttaagg ctatgggacc
     5281 agctaaaaaa gatatacaag ctattggtcc tgtaattgaa gtagaaaaag cagttaaaga
     5341 tacagcgcaa aaaattaaaa caagccttga aagctcggga tttgctccaa gtccgattgc
     5401 tatttcttca ccaagttcaa taatttctag tcttttatta aaaaataaaa ctaatatagt
     5461 agcaataata cttactatta gaacaagagg tatgtcatct aactttgtaa aagataaaga
     5521 gccactgagc catctcataa cttcttgtaa ttcatatctt gctactttca acaataaaaa
     5581 tgaggtgcct gctcttgtga cagcttgaaa accaatgcct aatattatca gtcttgctgc
     5641 tgaaaaacca tcttttttag ctagtaaaaa taatattaaa gatgatgtta gtccacaagt
     5701 tattgaaata attccagtag ttaaactatt tgtttttaat accaatatgc aaaagaccgc
     5761 tgcaatagat gaagaacttg tgacaccgat tatatcagga cttgcaagag gatttcttaa
     5821 catagtttga aagataaatc ctgccaatcc aaaagaccag ccagctataa ttcctgctaa
     5881 taattttggt aatctaattt ccataatcga aaaactagct ccaggaacag tttcactatt
     5941 taagacttta atcaaagttg aaaaagaata actttcatct ccgataagta aaacgaaaaa
     6001 tgatagactg attattatta ataaaaatag tgaggaaaat agtgttattc tattttttct
     6061 tttttgaata cctataatta aattttgcat tagttattaa cccctctatt tttcatagtt
     6121 acataaataa gtactggacc cccgattatt gcagtaatta tccctacttc aatttcacct
     6181 ggtttaccta acatacggcc gattatatca catataagca agagctctgc acctataaaa
     6241 gatgaagaaa tggtcattgt gcgtatatct ttgcttataa ataagccaca aaagtgagga
     6301 actataagac ctacgaagcc aataggtcca ccaattgcag taatacttga acataaaagc
     6361 acacttgcaa ttattgcaag tgatcttatc ctattaacat taactccaag accaacagcc
     6421 atttcatcac ccatagctaa agcgtttaaa tctgatgaaa taaatatagc tatcaagtga
     6481 cctaaaatta taaaaggtag tagtgtagat atagaagata atgtagctgc tccaaggcta
     6541 cctatttgcc aaaatctaaa tttgtctaag acgttattat tcggtaaaat taaaaaactt
     6601 acaaaactgc ttaaagccat actaacacaa gttcctgata aggcaagttt tataggggta
     6661 aggcctgctt ttccgcttac agcaatcgcg tatacaaaaa ttgcacttac taagccacca
     6721 atgattgcaa aacttatatg gcttatgctt gatgaaattc ctaaaaaaga aagaccaatt
     6781 actacactaa gacttgctcc tgtgtttata ccgagtatac ctggatcagc tattgggttt
     6841 ctagtaactg attgcatcaa tacaccgctt atggcaagac tagaacctgc taaaattgca
     6901 aaaatagttc taggtattct tttatatata attgatttaa taaaatcatc atttgtatta
     6961 cccattccaa aagctgctaa aaaatctctg atattaattt cttttgttcc aagctttaat
     7021 gacaaaaata ttgtaataag aagacctagg cagattacaa aaattatgcc taggtttatt
     7081 tgttttttat ttcgcatttt tgcatgcatt tcctaaaaga tttaggtatt cttcaatagt
     7141 atagtttatt gaaagtggtg ttggagtgca tgaggctgct aacggtgtat tatctggaat
     7201 tacagcaacg gcaccatttt taattgcatt tattttacct aaaagaggat ctttttgtaa
     7261 agcttcaaga gttttatcat caccataagt tatgattaca tcagcatcat ttatcttatt
     7321 tgcttcttct gcagaaattt cctttgcaaa actatcttca ctctcaaatt cttttaatga
     7381 ttcagggaaa actagaccta aatctgttaa ataatttgct cttggatctt tgctagtata
     7441 aatccagaat tttgatgtat ctgcagcatt aatcatagta aataatactt tttttccttt
     7501 gatttttcct ttgatttctg gatgtttttc taattctttg gatatacgag cttcagtatt
     7561 tttgattaac tcatcacctt ctttttccat acctaaggct tttgaatcaa ttttaatcat
     7621 atctctccat aaagtttgcc aaggtttaga tttgtatgct gctacaggag caatttttga
     7681 tagagtgtca taatcttctt tagttatacc agaataacct gctaagataa catctggttt
     7741 agaatttgat attgcttcaa agttaagtcc atccaaatcg tcaaataggt tagctttacc
     7801 atttagttct ttgatttttt cttctgtcca tggtaaaact cctttatcag cacttacacc
     7861 gtaatttgct tttgaaaatc caacaggaac tattcctaaa gctaatgcta catcatgatt
     7921 tccccaagca atagttgcaa ctctttcagg ttttttatct aatatagttt gaccgaaagc
     7981 atgatctaaa actattttat caggcgcatg ctctttagaa gtattttctt catttttaac
     8041 agaattagaa gaacaagcgc taaaaactat acacatagct aaaatagcta ttagaaaaaa
     8101 tttgtttttc ataaaaactc cttaaacata tttcaagtct attgtatcga taataattat
     8161 cattgtcaat agatacagtt acaaatttaa taatataatt ttttcaaaaa aggatctagt
     8221 ttttattttt agttaaatta tgtctatatt tttcattaac tcatcaataa aaatttgttt
     8281 gctaatatct ctttcttctg attttgtttc aaggattatt gctacatcat tcatattttt
     8341 aggtaaatac caaccatctg gcttatctga atatcccttg aagcctaatt gattaaaagt
     8401 agttatttga ccagtacctt gattgatgtt ttcttcaact tcattaaagc ctatacttct
     8461 cttgcataat ccctaacttg atcttctgtc cttaaagtca ttttctattc ctcgtcacta
     8521 aaattatctt caaaactaat aatatcatta ggagtgcaag ataaagcctt acatattctt
     8581 tctaaattct taaatgtaat tggtttatcc tttcccattt gtgccataac atttgttgta
     8641 agtcctgcca tagctattac atctgttttc tttagtcctt tttttgctaa ctgtatccat
     8701 aatggtttat agttaagtgc cataatatcc ctcttttttt cttcattaga tttatttaat
     8761 tatagcataa atattgattt cattcaatct tacattgatt tagtgatttg ttttagagaa
     8821 tttgttgtgt tattccgtcc ttattttgcc ataaattgtt ttaagtggga cctcttatcc
     8881 ttaccatttt tacctcctaa ttttgagtat aaaaaagacg atagagtttt taatttctat
     8941 cgtctgagat ttacatatta aattttcatc acaaaataag actctttaaa gaatctttaa
     9001 attcattggt atgctgctta caatatccat tattaaaatg gatattgtaa gcagcatacc
     9061 aactatttat tttttgagtt ttaaactttg gtagaagtct tgaactcctt atatttacat
     9121 aactatttgc ctctataact gttatgacac gaaaccaaca agcaagttca agcacctcca
     9181 tatctttatt caaatgagga ctaagatatt cacaaacttt atcataaacc tctttatctt
     9241 ttttcataaa aggggcatac aacttagcaa atttatccta aaattttttg ttgcctttat
     9301 caatcatttc aacgctcctt taaatataaa aatgatccta tcaatcttta tattgagcct
     9361 attttctaat tgataccttg caagaaagga ataatagctg ttcctatacc aagtaggaat
     9421 gtaataaatg cagaaagtca tatactgtca ttcttttcta ttaaatcatt ttgaagtgtc
     9481 tcaaagcatc catgatggct tcttcttttt caggtgtaca ctgtggaata atttgtttat
     9541 cctttttaga cttgttgtaa tgttctcgta attctattcc acatttcttt tttatctgtg
     9601 caatatataa tgtcgaaact tttaattcaa atttattcca aacatattct ttgatttgag
     9661 catatgttgc tttgctctcc gcacttgtca aatccatctc atccagctca atttcaacac
     9721 ttatgtgctt atcgacatca agtttggaca aaagtgctac cgtctcgacg tgatgcgttt
     9781 gaggaaatag atccaccggc tggactttct tcaattcata tcccaattct tggtagagtt
     9841 tgatatcacg cgccatggtt gcgacattgc aggagatata ggcgatgcga tcggctcctg
     9901 tttgggcgct tgctttgata aagctttctg tcaagccctt gcgtggagga tcaaccaaga
     9961 taacggttgg ttgaatccca tctttaagcc aattcttcat agcattttca gctgtgtcac
    10021 agacatagtg ggcgtttgaa atattgttca gctgagcatt ttttttacta ttctcaaccg
    10081 cttctggaat cagttcaaca ccgtagactt ctttgacatg cttggcgact gataaaccaa
    10141 tggttccaat accagaataa gcatcaataa ccacgtcatc tttttttaac tctgcaaagt
    10201 caatggctgt ttgatagagt ttctccgcca tttcagtatt gacttggtaa aaggctgggc
    10261 cagcgatttg gaagtcattt cccaacatct ggtccgtaat atagtcttga ccataaagag
    10321 tgcgccactc cttaccaaaa atcgcattgg tattctggtc gttgatattt tgcatgacag
    10381 acacaatctc tgggaactgc ttgataactt gttcaatcaa ttggtcaaca cgaaaaactt
    10441 ttggacgagt tgtcaccaaa acgaccatga tttgtcctga atagtgacca cgacgcacca
    10501 caagattccg aatcaatcca gactgttcct tttcgtcata aggttttaaa tcaaaacgac
    10561 ggagcaggtc tcgaagagct actacgactt ggtcaatgac aggatcctgg ataaagaaat
    10621 cttcaagggg catgaggtta tgcgaattct tacggaaaaa tcctgtttcc aagacaccat
    10681 tcactcgacg aacgggcacc tgcgccttat tgcgatactt gactggatgt tccataccaa
    10741 gcgtttcagc aacttctaca tctgcaattc cagcaatctt gtagagactg tccttgactt
    10801 gcttggtttt aaacttgagc tgttctggat aagaaaggtg tcctaaatcc gcgattcctg
    10861 aacgcaggta agccaaatct agatcttgat tacggtgtgg tgactggaca aggtattttt
    10921 caacttttcc aaagccaatc tttttattga ccttgaggac acgcatgaaa attttttcac
    10981 tcggtaaagc attctctaca aaaaagacca aaccatctac cttggcaact cctgcccctt
    11041 catgggtcaa atcaacaatt tcaacttcta caatatcatt tttctttaac attcttttct
    11101 ctttctattg gccgacaaaa aagacggcaa cgttacggtt accatccatt ataccatgaa
    11161 atttcttaag aaccaaaact cttgaagaag ttgacaaggg cttgccagag ggagcttaag
    11221 aagttaccac cgtcctctag cgccttatcc gcatcaaagt taaggttgat atttttaaaa
    11281 ctgtcgccag cttgtgatac gatgctttgt ttaaggtcat ttagggtttt agtgaaatct
    11341 gcattgctga ggatatcact ctttgagaga ttcaaggcaa aattgatgat gatattgatc
    11401 tggtttcctg ttatgacctg atcaagtttg taatttttta aggtatcttc aacaatcttg
    11461 cggatatctt cttctgtcag atttcccttg ctttctttag ctttggcgag tcctgacttg
    11521 atatcagcta gggcaacgtt taatttatta gcatcatagc ctgatttgtc cttgttttca
    11581 gcattgatat ctgacaaagc ctttagctct tcttgagcca aatctttatt ggcttgcggc
    11641 accttggctc cattagcttc tagcgaatag tagatcccag ccaaagcact ctcacctgta
    11701 actggaatgg gtgctgctac agtgattttg gcgtgttcca cacccaaagt tacggctgca
    11761 tttcggtaca tatcctgagt taccttagtg atgttttcag gtgtttcaat cttgacctca
    11821 agtggcgatt tgtcacctag cttttgaatc ttggctgatg aatacaactg taagctagag
    11881 tcattggcca cattcatgat tttagaataa acatcaggtg tcatggtctt gagttctttg
    11941 gtatctgttg aggcattgta gcccagtttt ttaagagttt gatttttttg gtcttcagat
    12001 agggaagaac ctaggacata ttcaggttgg acataggttt catcgataac tttttgaaca
    12061 tctgttgctg catggacgct attcatagct gttactgccc acaagatcgc agcgctagtc
    12121 agaaagagtt tctttctcat agggaatttc ctcctttact tctttagagt aatatatcta
    12181 tcttaaagaa aacttataac aaaaacacct ggtctagcca gatgttgaaa agagagtgaa
    12241 acatttgatg atgtaaaggt taagtcgtac ctgtctagaa taataatagt ttcctccatt
    12301 tacatagagt tcagcaccgt gaaaaatgga aatggggtga atataactat aagtctttcc
    12361 agtcgtatta ccaagcaagg gggcaacagt ctcacgagag tactgtttgg ctagagccaa
    12421 ggtattttcc ttgccatttt gggcgataaa atcgatatag gcaggtccaa aattataggc
    12481 ttgaacagct gtccagatat ctacaccctt cttctgcgcc agatagagat tgcctgtcag
    12541 agtttgaatg ccttgccgaa tgctagaggc attatcattg atggtgttgg tggaaccact
    12601 tgcagactca ctagactgca taacatcgcc ttcttttcct tttgtttcag tataaatcat
    12661 agcaagcaca agctcttcgt ttgctggggt gtctttttca ctcaatattt ctcgcaccat
    12721 gggttgatag gtcatgactt gtttgacatc ttgatgaacg cggtaagctt tatagccagc
    12781 aaaaaggaag actgctagta caagcactct tcgaattcgt ttaaacatta tttactttgg
    12841 atatcctcga tatttttgat taagatagag taggttccat tttcgttttg gataaactca
    12901 acagactcgg cgtcttgata gacgttattg ggaacgatga gctcaattcc atttgataag
    12961 gagagttttt ggttttcaaa tttctttaat tggcgactgg catcaatttc atcaaattga
    13021 acaggttctg gtacggcttc tttgacttgg tcaataaagc tcaaacgagc cgtcagattg
    13081 ttgtcaaaaa ggtcattagc caatttctca ggtgacaatt cattgctttc ttctaggttg
    13141 ttgaaaatag ctgatttgac cttggattga aattgaaaat catctgtgtt aaaagattca
    13201 gcaattctct gggctgtttt ttccagttcc ttgatagatt ttttaggaga aatcttagga
    13261 gcgacagcaa gaagattatc tgaaaaatag ttcaaaaaag tcccgttgta cttgattcgt
    13321 ttttcaatca ggtgatactt gcgactctga agattgacca ccaaggcctc gtcagcaccc
    13381 gttccaaatc caggcaggtt attctgagtc agcttgattg gattatcaac ttctcctccg
    13441 aggtgggtca aggtctcccg cagggcaatt cgcaagaaag cgaaatgttc tacaccttct
    13501 ttagaaaatt gaacaaaaat caagtcattg gtcttgagat tttcagaaat gctaaactcc
    13561 tctttccaga gattagccag cgttactgat gtctccaaca aatcgtctgt aatatgattg
    13621 aagaagggat tttcttcttc gaaaatccca gtcttggctt catctgaata cacatgttca
    13681 atttttttac gtaggtattc ttcgattttt ggagtaatat tgagaaactt atctgctaag
    13741 aacagctcgg tatcatccgg actgaactgg tgaataatgg ctttcttaat ataaatgtcc
    13801 ataaaagttt tattcctcgt ataatgggaa ggcatctgtc aattctttga ctgcacttct
    13861 cacttcttct aatacagcct cattttctga attcttaagg gttttaatga tgagttcagc
    13921 cactttgcga ctttcttctt caccaaatcc acgtgcagta atggctgctg ctccgatacg
    13981 aatcccactt gtcttgaatg gtgacaagct ttcgtaaggg attgagtttt tatttaaggt
    14041 aatattgact tcatccaaca agttttgagc aactttgccg ttttctacaa ctttagtcac
    14101 atcaacaagg aagagatggt tttcagttcc acctgaaata atacggaaat cagggtcttg
    14161 caagaagaca tctgccatag ccttgctgtt cttaattaca ttggcagcat attccttgaa
    14221 ggctggatcc aaaacttctt tgaaggaaac tgccttagcc gccacaacat gctctaaagg
    14281 accgccctga atacctggga aaatagctga attgattttt ttagcaagtt cttcgtcatt
    14341 ggtcaaaatc aaaccaccac gaggaccacg aagggttttg tgggtcgttg ttgttgtgat
    14401 atgagcgtat ggaactgggc ttggatgaag gccagccgca accaaaccag cgatatgggc
    14461 catgtccacc atgagcttcg caccgacagc atctgcgatt tcacggaatt ttgaaaaatc
    14521 gataatttga gaatatgctg aagcaccagc tacaatcagt tttggtttta cttcttgggc
    14581 ttgtttcaag atagcatcaa agtctaagag ttccgtttca ggatcaacac tataagaaac
    14641 aaagttgtag gtttgaccag agaagctaac aggagcccca tgagtcaaat gaccacctga
    14701 tgccaaatcc attcccataa ccgtatcacc tggctcaatc aaggacatgt aagccgcaca
    14761 gttagcttgg cttcctgaat gtggttggac attggcaaat ttagcaccga aaatttcttt
    14821 tgcgcgttca atagcaagag tctctacaac gtctactaca tcagttccac cataataacg
    14881 gcgtcctggg taaccctcgg catatttatt tgtcaagata gacccttgag ctgccataac
    14941 agccttggaa actacgtttt ccgaagcaat taactcgata ttattttgtt ggcgttcttc
    15001 ttctttggca atagcattcc agagatcagc atcatatgct ttaaaatcat ctttgtcaaa
    15061 aatcataggt cttctccttt attgtgtgac tagtccatta gtttgatttt acaataagaa
    15121 aatcaaacta aaagatgcga ataaaccgtt tctgcatttt atcacaagta tagccaactt
    15181 tttcataaaa tgcatgagca cccagacgat gattggcaga atttaagcgg ataaacccat
    15241 aaccacatct tttggcttct tgttccaacc cttgtagtaa acttttaccg ataccttcac
    15301 cttgcgcttg aggtgaaact gctaaagcta agatattaaa tcctgctttg gaatagagtg
    15361 attcgtaaac ttcagcgtgg acatatccaa gtaagacatg attagctgca tcctcatagc
    15421 caagtaggaa atgatgggaa tcctgagaca gtctagctag ttggctagcc gtttcctcta
    15481 gactaaaagt ataacccaaa gcctcttggt tgatgtcaca tatcgctttc acatctgttt
    15541 cttgcaaatc tcttagcatt tcaagcctcc tcaaaagaaa tctctggcaa ccgagcaaga
    15601 atatcttctc gtttaattgc gccttggcgt aagattttca ccttgtctcc agacaaatcc
    15661 acaatagttg aatcctgtcc agttagaaaa gcatcgtctt ccagacccag aacctcttgg
    15721 tcaaaatcct tcagaatttg ttcaaaggtt acaccacttg cctgacctga gatattggca
    15781 gacggcccaa tcaagggacc tgtctctcga attaaatcca gtgtgatagg gtgactgggc
    15841 atccgaaatc caatagttgc aaggtcagaa tttacccaat agggaactcg gtcattggct
    15901 tcgagaataa tggtcaaggg acctggcaaa aaggtctcta caagtttttg tagataagtt
    15961 ggctgattct tagaaaagtg caagatatcc tcgaaagagg cgatattgag attgagtgcc
    16021 ttatctctag gacgacgttt gagttggtaa acatggtcaa ctgctttttc atctaaggcc
    16081 ttggcaaaaa gaccataaac agtctctgta ggtagaacga cagctccacc attttccaac
    16141 tcttgtctaa tcctgtctat catcaaccac gaccatccta ttttgaccaa attggtcctt
    16201 gagtgttcga actctttttt caggaagatg tttcctaaaa agttcgggaa cactttgacc
    16261 ttgcttgtat ccaatttcaa ggtaaatctt accaccatct ttgagatagt cttttgcatc
    16321 ttccgcaatt ctacagtaaa tagctaggcc atcctcgtct gcaaagagag ctagatgagg
    16381 ctccgaatgc aaaacattca agcctacctc tgactcatct tcacgagaga tatagggtgg
    16441 attggataca attatatcat atttttcaga aatttctgca aaacaatcag attttttaaa
    16501 aaatatatta agattttgat tgctagcatt ctctgatgca agctctaagg cctcttgaga
    16561 aacatctgct gctgtcactg accaatctgg tctatttttt gctagagcga gagcaatagc
    16621 tccactacct gttccaatat ccagaactga aagattcgtc tcaagatttt cagttagaat
    16681 aagctccact aactcctctg tttctggacg aggaatcaaa acccgttcat ccacctttaa
    16741 atgcattcca taaaaatctg cctgtccaat gatgtactga gctggcttgt gagctgctag
    16801 ttgctggtaa atatcttcta caaattgttt ttcttcctct gttgtcacct cctgctggag
    16861 ggcaaaaata aagtctgtaa aagatagatt tttcagacta cgatagacaa aagagaggct
    16921 ttccgcttcc tctccttgtc ttatcaactc ttcttcaaaa tttgaaaata attgagctaa
    16981 tttcattatt tgtttaattc ttttagtttt tgtgtttggt cataaagcac caaggcatcc
    17041 acaacttcgt ccaatttacc agacaaaatc gtatctagtt tttggagggt caagccgata
    17101 cggtggtctg tgacacggtt ttgtgggaag ttataagttc ggatccgttc tgaacggtca
    17161 ccagtaccga ttgtcgactt acgctcagcg tcttgttcat cctgagcaat ctgagcaaag
    17221 tggtcagcga cgcgtgcacg gataatcttc atagccttct cgcggttctt ctgctgggta
    17281 cgttcttcct gcatctcaac cttgatattg gttggcaagt gaacgatacg aacggcagtc
    17341 gcaaccttat tgacgttctg tccaccagca ccagaggcgt gatagatgtc gacacgaagg
    17401 tcttttggat caatgtcgta ttcaacctct tcaacttctg gcataacaag aactgtcgct
    17461 gtcgaagtat gaacacggcc ttggctttct gtcacaggaa cacgttgcac acggtgggca
    17521 cctgattcat acttaagctt agagtataca gactgacctg aaaccatagc aaccacttct
    17581 ttaaaaccac cgacaccatt catagaggct tccatgactt caaagcgcca accttgggct
    17641 tccgcatact tttggtacat agttagcaaa tctccagcga aaagtgccgc ttcgtctcca
    17701 ccagctgctc cacggatttc aaggatgata ttcttgtcat cgtttggatc ctttggaagg
    17761 agcaaaattt tcagtttttc ttcatattct tctttttcag ccttggcatc tttgagttct
    17821 tgcttggcca tttcttccaa gtccgcatct ccgcctgatt ccttaatcat ctcttcggca
    17881 tcgacgatat tttgaaggac ttgtttatac tcacggtagg ctattacggt gtcacgattg
    17941 gaagcttctt cttttgaaag ctccataaaa cgcttggtgt ctgaaacgac atcagggtca
    18001 ctcagcaatt ctcctagttc ttcataacgg tcttctacag cttgtagttg atcatagatg
    18061 ttcatttttt ctccttattt ctcaattgtt aaatcataga ttgctactac ttcattctcg
    18121 gatatttccc cagtttcttt aaatccataa ctgagataac aaaatcttgc ctgttcattt
    18181 tctggttcat aagacaacca aagtttattg cttaaacctg ctggcgctgt tcgaacatag
    18241 tctagtactt tatccataat tggtttaaaa tatccttgat tttgaaaatt cttatcaatc
    18301 ataaaacaaa atagtaaata atttccacta ctaattacga tctttttatc ataagctatc
    18361 atcacaaaac ctataattac atcattatca taaactgcca atggagctac aaaatctcca
    18421 tttttagtgt agacgtatgc ttcagctaaa ctaattgcgt tggttgcaat gaattgtttt
    18481 tgatattcct tgacatccaa atttaaaaca tcaaaataat tttccattgt aacatctctt
    18541 agttcaattg tcatagtttt gctccttgtt agaggttatc attggcgcaa aataatgttt
    18601 acggcaaacc gagatatagg tttcattacc accaatctgg atctgttctc catcgtaaac
    18661 gggcagtcca tcctgtgttc gcaacaccat ggtcgccttt ttcttgcaat actgacagat
    18721 ggtcttgatt tcgtcaatct tgtctgctaa aagcaagaga tatttggaac cttcgaacaa
    18781 ttcattgcga aagtcatttt tcaaaccaaa agccatgatg ggtatgtcta actcgtccac
    18841 aacacgagct aggtcgtaaa catggtggcg tttaagaaac tgggcttcat cgaccaaaac
    18901 acagtaaggt ttttctggta ggtctcggat atagccaaag atatccgttg tttcctcaat
    18961 cgcaagggca gggcgtttca tgccaattcg actcgacaca tagccaacac cgtcacgcgt
    19021 atccagagcc gaggtcataa tgacaacacc ttttccttgc tcctcatagt tataggccac
    19081 cttgagaatc tcgattgtct ttccagagtt catggtccca taacgataat acaactgtgc
    19141 catgtttctt gcttcacgtc catttctaaa tttttgctac attctagtat atcataattt
    19201 tcttaagctt taaacggcaa aatgtggtaa aatagaagaa atcaaaaact agtggaggaa
    19261 gctattatgc catttgtacg catcgattta tttgaaggac gcacgctcga gcaaaagaaa
    19321 gctcttgcta aggaagtaac ggaagcggtt gttcgcaaca ctggagcacc tcaatctgct
    19381 gtccatgtca tcatcaacga catgccagaa ggaacttact tcccacaagg ggaaatgcgt
    19441 accaaataag ctagcttaag cagaattgct taggcttttt caatctccaa gtagcattca
    19501 ttgaagaaat atcctaaatt tgttacaatt tgaaaagaaa cttggagaat ttccaagaaa
    19561 atagctatta attaaaggaa acattatgat tacacgtgaa tttgatacca tcgctgctat
    19621 ctctactcca ctaggtgaag gggctattgg tattgtccgc ctgagcggaa cagacagttt
    19681 tgctattgcg caaaagattt ttaaaggaaa agacttgaac aaggttgcca gccacactct
    19741 caactacggt cacattattg atcctctgac tggtaaagtc atggacgagg ttatggttgg
    19801 ggctatgaag tctccaaaga ccttcactcg tgaggatatt atcgagatta acacccacgg
    19861 tggtattgcg gtgaccaatg agattctcca gctagctatc cgtgaaggag ctcggttggc
    19921 agaacctggt gaatttacca aacgtgcctt tttaaacggt cgcgtagatt tgacacaggc
    19981 cgaggcggtg atggatatca tccgcgccaa gacagacaag gccatgaaca tcgcggtcaa
    20041 acaacttgat ggttcccttt ctgatcttat caataatatc cgtcaagaaa tccttaacac
    20101 acttgcccaa gttgaggtca atatcgacta tcctgagtat gacgatgttg aggaagccac
    20161 tactgctgtt gtccgagaga agacaatgga gtttgagcaa ttactaacca agctccttag
    20221 gacagcacgt cgtggtaaaa tccttcgtga aggaatttca acggctatca ttggacgtcc
    20281 caacgttggg aaatcaagcc ttctcaacaa cctcttgcgt gaggacaagg ctatcgtaac
    20341 cgatatcgct gggacaacac gagatgtcat cgaagagtac gtcaacatca atggtgtacc
    20401 tctcaaattg attgatacag ctggtattcg tgaaacggat gatatagtgg aacaaatcgg
    20461 tgttgagcgt tcgaaaaaag ccctcaagga agccaacttg gttctactag tgctaaatgc
    20521 cagtgaacca ctgactgcgc aagacagaca acttcttgaa attagccaag ataccaatcg
    20581 cattattcta cttaataaaa ccgacctgcc agaaacgatt gaaacttcga aactacctga
    20641 agacgttatc cgtatttcag tccttaaaaa ccaaaacatc gacaagattg aagagcgaat
    20701 caacaacctc ttctttgaaa atgctggctt gattgagcaa gatgctactt acttgtcaaa
    20761 cgcccgtcac atttccctga ttgaaaaagc agttgaaagc ctacaagccg ttaatcaagg
    20821 tcttgagctg gggatgccag ttgatttgct tcaagttgac ttgactcgta cttgggaaat
    20881 cctcggagaa atcactgggg atgctgctcc agatgaactc atcacccaac tctttagcca
    20941 attctgttta ggaaaataag aaaaatccat gatccttcat tcggtcatgg attttattgt
    21001 ctttattagt aatctggtct taagacccct gttacagttg ccttagttgc ttcgtagtcg
    21061 ccatctacga caaccttgat aatgcgtttg gcatcttctt ctggtgctgg aacaagaggt
    21121 agacgagtgg gtccagcttc aaatcccata tagttaagaa ttgccttaac tggagcagga
    21181 cttggataag agaagagagc attaacctta ggaatgaatt tacgctgaat tgctgcggct
    21241 ttcttcatat cgctttctgc aatggcagta aacatctcgt gcatttcatc cccatttgta
    21301 tgagaggcaa cagaaataac cccatccgcc ccaaggttca tggcatggaa agcatctcca
    21361 tcctcacctg tataaatcaa gaactcttca ggcttgtgct caatcaagta agccatatta
    21421 gccaagctag tacattcttt gacaccgata atatttggat ggtcagccaa gcgaagcatg
    21481 gtttctggag tcaattcgac aactacacgc cctggaatgt tatagataat aattggtagg
    21541 tcagaagcat ctgcaatagt cttaaagtgc tgatacatcc cttcttgaga aggtttgttg
    21601 tagtaaggaa caatagcaag cccagctgcg aaaccaccaa attccgctac ttctttgaca
    21661 aactcaatag agtcacgcgt atcattagta cctacacccg caatcaaagg aacgcgtcca
    21721 ttgacaacct tttgtacagc cgcaaacaac tccaactcct catcgtgggt caaagttgga
    21781 ctctcagcag tcgttcctgc gagaagaatt ccatccgtat gatgggccaa taaatgctca
    21841 atcaaggctg gaatagcatc aaagttaata gaaccatcct catgaaaggg ggtaataaag
    21901 gctgtaatga ttttacattc ttttaaatct tgataagaca tgaaaacacc tctctatttc
    21961 aaagaaggag ttcatctgaa ctcctaaacg atatgactat tttaattcaa atttcaattc
    22021 ggctgttgga cgaaccaatc cacgttcatg aagagtttca gcaatctgaa ctgagttcca
    22081 agcagcacct ttgagaaggt tatctgaaac aacccacatg tgaattcctt tttctgcatc
    22141 caagtcttta cggatacgac caacaaaggt atcacgcgaa ccaactgcat tgatagcttg
    22201 aggatagatt tgatgagcta catcatcttc aagaacagca cctgggaagg ctgcgatagc
    22261 tgcttttact tcttcgattg gagccacttc ttttgtttcg atataaacag actcagagtg
    22321 agctgacaag actggaatac gcacacatgt tgcagatact gcaatgctat catcttccat
    22381 aattttctta gtttccttgg tcatcttcat ctcttcgtac gtgtaatcat tatcagtgaa
    22441 aacatcaatt tgtggaagag cgttaaaggc gataggataa tgtttcttgt caccacctga
    22501 aggcaaaatt tccgcatgca aatcacatgg tttcacacca tcattcaaga cttcacgaag
    22561 ttcacgttgt gtctcaagaa ttgctcccat accagcacct gaaacggctt gataagttga
    22621 aacaatgata cggtccaagc cccatttttg gcgaaccggc tcaagagcca ccatcatttg
    22681 gattgttgaa caattagggc aggcaatgat tccgttgtgg gcatcaagtg catgagcatt
    22741 gacctctgga acaaccaaag gaacatctgg attttgacgg aaataagatg tattatccac
    22801 tactaccacg ccagctttta ctgcgtatgg tgcatactta gctgatgtag aactacctgc
    22861 tgaaaagaga gcaatatcaa ctccttcaaa agctgtttca gtcgtttctt caattgtaat
    22921 atcttgatct ttaaatttca atgacttacc tgctgaacgt gcagaagcaa ggtaacggat
    22981 tttatcgatt ggaagtgttg attcttccaa catttttatc atctgagcac cgacagcacc
    23041 tgtcgcgccg actacagcaa ctgtatatcc cataaataac ctctttcgga attttctaaa
    23101 aatttctata atagaagtat tatactactt tttccatgaa ttgcaaagct ttttcatcat
    23161 tttttggaaa ataaaaatcc cagtcgctag actagggact aagaggcatc ttcatgtgat
    23221 gagcaggttc acacaactca tcaaggtccg ctcctgcgtt atgacctcct tatgctcaat
    23281 agtagtccga agactaccta tcgactcatc gcatattcta tattactaga gatacttgat
    23341 tttgtcaata agaaattttt tcgatcgagt ataacaaaaa actctcgtat tcaagagttt
    23401 ccctatacat atcatgctaa ttgccgggat cgaaccggcg acctcatcct taccatggat
    23461 gcgctctgcc aactgagcta aatcagctta cttaagaagt atactatatt cagaaaaact
    23521 tgtcaagttt ccttagaaat tttccatagg aaaaagccag gtaagaacta cctagcttat
    23581 cttcttctat ttacttaaat caattcgacg accaatttta ccaataataa tcgccccaat
    23641 aatcaatgaa gcaaattcac cgattcctgt tgtaaaccaa gtaaggaaga atggtaattc
    23701 tgctacaata tttaactctg cagcgatagt aaacatggaa attgaaaaga ggattgaaaa
    23761 gaagaaatga tctttttgaa tcaatccgtt aaagaggtaa tccttgctat attttgcaaa
    23821 aagccaaaca cctaaactga ggaatactaa ggttgaacca ccaccaacaa agacatctag
    23881 cagtccgaag ctaaagaaat tagcaatcat acaaccgatg gtaactccga tgatgtactt
    23941 aggattgtaa aaagccataa agttcatcat ttctgaaata cgaaactgat aagcaccata
    24001 gctgatggca tttaggggcg gtgtgacagt caaaacgacg tagatagcag cgacgattgc
    24061 aatatctgca acatcacgaa tagttaattt tttcatcttt tctcctttgg cggttgcccg
    24121 cgtgtaatat gcttggtgaa agaagctaag caccaagggt tgctttattc aaccctacta
    24181 gtatagcaca atagcctgct ttatgctata cttaacacat gaaaattcct attcaaaaat
    24241 tttttaacaa tgaaatctta gcctatctct tttttggcct tgcgacaact ctagtttcga
    24301 ttctctcacg actagtcatt tatcaactaa gtcatcagga actcctggct actgccctag
    24361 caaatattat cggtatccta tttgccttta tcacaaatga tacgattgta tttaagcaaa
    24421 aaaagaaaaa tagacttatc cgtttagtga aattttctct tgctcgcctt tctacttttc
    24481 tgttagactt gtttttaact tttctctttg taacccaatt tcctcacatt atagggcaat
    24541 tcgtaactga aaacattgat aagataaatg ctattgaaac aataattgca caaatattca
    24601 ttattatcat caattatata ttgagcaagg cctatatttt tagaaaataa tgctccattt
    24661 atgagccttt taattgcctt ctataatgat ttaggataca atgaaacacg aaacattgaa
    24721 aggaaaacag tatgttaaaa aatctaaaat cgttcttgct tcgaggaaat gttattgacc
    24781 ttgctgtcgg tgttgtaatt gcctctgctt ttggtgctat cgttacttca cttgtaaacg
    24841 acattatcac tcctcttatt ttaaatcccg ctttgaaagc tgctaaagtt gaacgtatcg
    24901 ctcaactttc ttggcatgga gtcggctatg gtaacttctt aagtgctatt atcaatttta
    24961 tctttgtggg taccgccctc ttctttatta tcaagggcat tgaaaaagca cagaaactga
    25021 ctggcataaa gaaagaaaaa actgccgaaa aaaaaccaac cgaattggaa gtccttcaag
    25081 aaataaaagc tctccttgag aaaaaataat cgattaaaag gatctagcgc aaagctaaat
    25141 ccttttttct ttactctttg ggtaacttgc ctgctttttc aagcattttt ttgatcagat
    25201 aaggcatctt aacattctcc cgcccttttt tctcaatcag ttttttcaca aattctggca
    25261 tttgtaaatc ttcagattca gctaaaatgt ttttcgtctc gtctgaagga actaactcat
    25321 caaaggtctc ttcttctggg agaaattcct taaactcttg attttcattg actctaactg
    25381 tattgaccaa agcatcaatc aaacgagaat ctgtatttgg cattggtgga cgatggtagt
    25441 ttaccccaaa ttcctggcat aagtcataac attctacatc attgtcaaac aagacctcaa
    25501 tatgctcact gatgaaacta ataggtacaa aaatataatg gtctggatgt tctgtctgtt
    25561 ctctgagata ctccaaaaca tctggtttaa tccatggaat accaatatca ctctcactct
    25621 gccaagtgtt ggtatattgt tctgaactca agcccagttt ttcagcgact agcttgctat
    25681 tttcgaaaat ttggtctata taaggatcac caaagtccaa ggcaaaaatg ggcacactat
    25741 gggctgaaaa gatgacttta aagctgtctt gctttacttc ttcttttaaa atcttagcaa
    25801 tttcatctgc ccaatagttt aagagcactt cttcctgata ccagtcctta atgaccaaaa
    25861 attgaatttg tttgctttct aaaaattttt catagcccat gacagagtag aaagaataat
    25921 ggggctccaa aatcaagcag atacattctt caacaccatc agtttccatc tgcttgatca
    25981 cgtctggaat aaagggacga gaaaatttgt tggcaaagta gataccgtac tcctccccta
    26041 aacgttcttt gactaaattg acctcctcac gtgtaatccg ctgcaaaggc gtcccaccga
    26101 tacgaatata gttgtcatag agagtctgga tttcgtggtc ttggggtcta actccacgac
    26161 gaatgtttgt aaagaattct gctactcctt caaaactaat ctcctctgga gatccaaagg
    26221 tcatcattaa tatggctttt ttcatgttat catccttatg atattatttt ctctatccat
    26281 tctatcatga aagaaaaaaa tagtaaacgt ttcctacgtc tactatttct tttgctcttt
    26341 tgttttttta tctcgtctta taattaggat gataaggaca agaagtaaga ggacgataat
    26401 aaggagtaga aaggctagaa tgtaaatcca atgactggga attccgtgat cgaaataccg
    26461 tgttcctact gcttccccac tttcatcctg tgctactttc accggtgcat ccgttatttt
    26521 agctaaaagg atatgtcgtc cattagttat gttaaggaaa caggtgctta ataaaacaat
    26581 cttgtccgtt gaggtcaagg aaacatctcg cttgtacttg gctttactta gcagatattg
    26641 atagtaagcc tggtgttcct catccttgga actcaaggtt cgataaatct ccgtgtcata
    26701 ggcatccact tctaaaatcc caaaaatttc aagaccacgt tctcgaccat tgtagtagat
    26761 agaaccgtag cgatgctggt cgaagaattc cttatcagca aatttcttaa tctcaccgaa
    26821 catagcccct gaagccatag agtgtccgta gatgatcgta ttaaaatcag taaagttggg
    26881 attaaagcga tagtcgagaa aaattgatcc cattatcgta taatcgccaa aggcattgcg
    26941 gtcaaggtat ttgacattat cctgactttg tagaagcgga tagtctacct tggtcccatc
    27001 aaggctaatc caaccgcaaa catctttgtt caagtgctgt agggtttcaa aacctgtgct
    27061 cgaagcatcc ttttcaatag gattatagtg atcatagtca cttgcttcta ctactctctg
    27121 ccaactaaaa agagctacaa aaacacagaa gaataccaga aatacgtttt taaatcgcgc
    27181 tcttttttga accgtcatca gcactccttt ctatgcgaga tttcttaaaa ggaaaggagg
    27241 cgggacaaaa ccgcctcttt tctattcacc cttagtcagt aaaagggtct gcttcttgca
    27301 ttttttttac tctctcttct acgacgtagg atcaagtaga ggacaaggag taagaaaatc
    27361 aagagcaaga acaatacaaa caagataagg taccaaatcc atagtgggat tgatgagagg
    27421 aaacgtccaa gagacgagtc atcaaagaca ctgtatggaa atggttttga tttttttgta
    27481 tggaaagtat ttttagggac ggtgtctgta atctttgcga ctacgatatg acgaccattg
    27541 gtcacatcga gaaaacaggt actgagtagg atgatacgat cactcggtga gagtgagata
    27601 tcccgcttgt gcatggcgac tgagagcagg tggtctagat aggcctgctg gcggtcctca
    27661 ccctgtattc ctggatcata gatgttaaag tcataggcat caacctccaa catctcaaag
    27721 atctcgagcc ctttttccac accattgtag tatatactac cgtaacgatg ctggtcaaaa
    27781 aattcctgat cagcaaactt agccacatca ccaaacatga ccccattttc tacgtggtgc
    27841 ccgtagataa tggtattaaa gtcttcgaac ttaggattat ttcgtgcatc gagaaagata
    27901 gcgcctgtcg ctgcaaactc acctttggag tccttgttga gatacttttc attgtccttg
    27961 gcttggacta agggatagtc gatattggtg ccatagacat tgatccaacc gaggacttcg
    28021 ggattgagtt cttggagttt gctgaagcct gaaaaactgg ccagctcatc ctgttgcgtc
    28081 gtgacaggtc gataagcttc gtactcactt gacgaagcta aggagtagac ttggttggaa
    28141 tcccaaaggg cgtagaaacc aaagagaaag atcaaagctg caaaaatgag cagcaagtga
    28201 ttgatcaccc catccacagc aagaacgaga cgcctagaca gactcttttt tggtttctca
    28261 cgcttggttt tcatcatctg cccccagccg tttaggcttc tctacgtttt ttagacaaga
    28321 caacaaatcc agccaaacca agaccaatca tcaaaatgaa tggaaggtta tcaatcaaga
    28381 gaccagtagg agtaacgtcg tcgattttgt tagtaacttt gttgtcgttt ttcttttcac
    28441 ctatgaggat atctgttaat gtaaaatcta catttttttg tccttgagat gtttgttctg
    28501 caccatttgt agtataaatt gatgaatctg tataacctgc tactccagtt tcagttactg
    28561 tatatttaga acctgctggt agttgttcaa ctgtaaatgt ttcaccatct ttaagagtaa
    28621 aattgtactc aactgtatct gctggggtca ctactgccaa cacctctgac ttagatccat
    28681 gttttactat aatattcgta acaggggttt ctgctgtttt atttgtactt ggaagttgaa
    28741 tcttgatatg gaattggaaa tctcttgttt tatcccctga agctccatca acttttttag
    28801 taattgttaa tgctttcgca ttggggtcta cttgactcgg atcatcagga ttaggctcct
    28861 tacttgcgtc tttggtatat gtgttatcaa ataaattata aacgccttgt tcacttggtt
    28921 ctactttagg ggcgttagat ttattatttt ccttaaagta tactgatgaa atatagacac
    28981 caccatttac tttattctta acaataacgt gcatttcata tgtacgtttg tcgtatctca
    29041 tggcatcaat tgttttacca tttttggtaa tcgcctgcca tccagttttt gcttccgcta
    29101 catcataaac gtattcacca gcatggccat aagcaactcc cgaaaaaatg tcttctgttg
    29161 ctttttgaat cttatcagca gttgggtgat catttttatt gtattctaca tttctatctg
    29221 gaattgcaac tccggtttga tatggcgcac cgttagaaga ttgtcctgtt ttttctgtaa
    29281 acttaaatgt aaatgtcgct gttggtgttg ttattccctc tgcaatattc aacgttttat
    29341 taatcttcac aacagcatta ttttcaccat ttgctttggt tattgctgaa ttatcatccg
    29401 caaaagtcgg gacacctctg aatacggaca aagcggttat agctgcaatg cttgcagtga
    29461 atagcttttt aaagaatgtt tttttcatga ttatttcttt tgttttttta ttttcttttt
    29521 tcattatgat catcaaaagc ctcgtcttct aatgactgtt acaactttgc cttgagtatc
    29581 ctgtataggg atggttccaa aagcacgact gtctacagcc gttgttcgat tgtccccgag
    29641 gacaaaaagt tgtcctgctg ggactttcat cgggaaggtt gccccttcct tatagagcag
    29701 cgtttctttg tagatatctt gctcttgttg aggagaaccg ttgatgatga gaccattttc
    29761 gtttatatcg attgtacttc cttcggttgc tatgacacgc gccactcttt ccttaccttt
    29821 ataactatag actagcaaat caccaatcga atagcgttta tccaacctat aatagacgac
    29881 caagtcgcca tcttttaagg cgggcttcat gccatcgtca ttgtatctta ataatccaaa
    29941 gacgaaaaag taaaggatgg ctagtacaaa tccaaccatc agaagtttac tgactaagta
    30001 aaggatatct ccccagacac tcggcggaga cttatcccga ttgacttgtg ttactggttt
    30061 cttatgtttc tttttaagca gcatcacttc ctcctattca ccacaaggtg accaagtaag
    30121 atgataaaga agatccctcc tagaggaaga acgactccaa gcacgagagt gctactcaag
    30181 aagtcaattc ccgtttcagg tacgctgttt ttattattcg tgactgtcgc agacttattt
    30241 gcatcaagag ttccttcttt tttatcatag gacacctgat acccacgaga cgaacttgct
    30301 tcttcttcga tactataacg agcatttaga ggaaggtcga gaatcttgat ggttttatct
    30361 ttctttagat caactgtcgc cttaccattg gtgaattgta gcgttgtttt ttgattattt
    30421 actattgcac tatacgatcc attcaatggt ttattttgcg catcctttac gttaatggta
    30481 atcttaaagg attgcagaag attagcaaaa gcacctgtaa ctttttttgt gactgaaagt
    30541 gtcggaagtc tgtggttggt gacgattgtt tgaacatcct ctgacaaagt cccctcttgt
    30601 ttttcatagg tgacatgata tcccgttcta gagttctcta cttcttccac cttatagtgg
    30661 gtatcacgag gcagataact gagggcagtt tcctgactat ttttgagaga aatctgtgct
    30721 ttcccgttag tcactgttgt attcccaaac ttgccgttaa tcggcttgcc atccttatct
    30781 gaaagggtaa cattaattgt gaaagattta ttaggtgatt gttcaccttc taggattttc
    30841 tttacggtga gacttggaag ctgtcggtaa ataactttga aggatggttt ctctttcgta
    30901 cctgtctttt gaacttcgac tgtgtatccc ggagcgtctg gtgctttcag ttcgtagtca
    30961 tatcccttag ctacctttgc aaaactagta ttttcagtaa aactattcgt ttgaactgga
    31021 ctagtgacct ttcgatagga atcctttata cttccatctt tcttttggtt taagtttaat
    31081 tcgacactag gtggacgatt tgctgatgga tttgattttc catccacacc tttccactca
    31141 atctctacag gaaccgtcaa tggatctgac ggcttgaaag tgggcttctc agaatagtct
    31201 tttattttgg tacgtgaggt cccaatacca taggaatagg caacttttgc ccccttgttg
    31261 gagtagagtt tagtagcatc ggcttcttcg gcatcatcac tagtaagtgt cttatcaccc
    31321 gcaatcgcat caaatgcctc ttggctagag gtgacagtaa acttgagaac gtacttggcg
    31381 tcatcctcta aagtgtaact cggattaaac ttggctgtta cttccactaa tccctgttcg
    31441 ttcttcttag tttcaatcgt aacttgattg tcattcagtt cttgctcgtt accatccttg
    31501 attttgacga cacgaaggtg tgaagcatca ccaggtaaca gctgcacgta cttggacaag
    31561 acatctgata tagttacatg gtgtacgcct agaggtagaa ttttatctgt gatttctttg
    31621 aatttttgtt gcaagtcatt ttcattattg gcagaaaata tttcgttggg gattccagaa
    31681 ttataaccac tgatatatcc tttaagagat gtgatactat cgtttgaacc tatatatctg
    31741 aatttgattg aataaaagcc atctattttt ggagctatta aactagatat attcagcatt
    31801 cctctctcta aaccagaggt aaaccaatat ggagtatcaa tcatacgtcc cacatttgga
    31861 ttagaataat agttatatat tgttctccca ctattagact cgtaatacat attagcttcg
    31921 ccatctgaca gcagaataac tacttttttt gccccagccc ttgcactttg caacaatctt
    31981 tgagcttcag ttaacccagc atttatattt gtcccagtgc caatgcccgc gtccatacca
    32041 taagaacgac tagagtcagc aattgttaac gaactaacaa tattttttga gctattagaa
    32101 tccgtgctcc aagatactaa agttttagca tcatcatatg aagagatatt tgaataccaa
    32161 ccagctcaat ttggccaagt tccatattga taactcagat aatattcatt ataataacgg
    32221 tcattatact gattatcaat ctttccggca aaaccaacta tagacagacg gttttgggaa
    32281 ttagaaagaa ttgtatcaat gagcccctga cgaccattca cacctttcag tgtatgtttt
    32341 agtgcttcaa tcctactaat gtatcgtcta ctagagtaag accacacatc tcgctcttcc
    32401 atactccctg aaagatcggc aaccaagact acatccaagg gttctgactg ggtctccgtt
    32461 cccagtttag atgtgatatc cagtgacaac tcatactggt ctttttaccc tgatatcgga
    32521 gtaatcgttt tgtgcagagt tgtctgaggt tcagttattg aatctgcacg taaagaatta
    32581 attggtgcac acaaaaaaag aatagcgaga aagataacta aactactggt aaaatattga
    32641 atcttcttaa aatcatattg aacgttcatg ctatctccct tgctagaata tgttttaatc
    32701 tgatactata taaatctgag acttccataa gataattgta taataatatt aacttcgtgt
    32761 caattaatgt gtttgaaaac atgttattat aaattacaaa aaagtatgat tcttctttgt
    32821 ttttcaactt tttctgtggt aaaatggaaa aaatagtaaa aaatttcata aaataaagat
    32881 gcatatattt attctaatcg ctcgaaaatt tcttttgaaa gtcttctgaa tttgaattat
    32941 tatatttttt caaaattcat aaaatttctc aaatcatatt tttccgaagt tttgtattct
    33001 attttatgat aaaaaaggag tttttttatg acttatccaa atctcttgga ccgcttctta
    33061 acctacgtta aggtcaacac gcgctctgat gaacactcta ctactactcc aagtacacag
    33121 agtcaggttg acttcgcaac aaatgtccta attcctgaaa tgaaacgtgt tggactgcaa
    33181 aatgtttact atctaccgaa tggttttgct attggaacct tgccagccaa cgatccgtct
    33241 ttaacacgta agattggttt tatatcgcac atggatactg ctgattttaa tgctgaagga
    33301 gtcaatccac aggtaattga aaactacgat ggtggtgtga ttgaactagg gaattctggt
    33361 ttcaaactcg atccagccga cttcaagagt cttgaaaaat atccaggaca aacactcatc
    33421 acaacagatg gaacaacctt gctaggtgct gatgacaagt caggaattgc tgaaattatg
    33481 acagccattg aatatctaac tgctcatcct gaaattaagc actgtgagat tcgtgttggt
    33541 tttggtccag atgaagaaat cggtgttggt gccaataaat ttgatgcaga agattttgat
    33601 gtggattttg cctacactgt tgatggtggt ccactaggtg aacttcagta cgagactttc
    33661 tcagccgctg gtgctgaatt gcatttccaa ggccgtaatg tccaccctgg tactgccaaa
    33721 gggcagatgg tcaatgccct tcagctagca attgattttc ataatcaact tccagaaaat
    33781 gaccgacctg agttaactga aggttaccaa ggtttttacc atctaatgga tgtgacaggt
    33841 agtgttgagg aggtgcgtgc aagctacatc attcgtgatt ttgaaaaaga tgcctttgaa
    33901 gcgcgtaaag catccatgca atctatcgct gataagatga atgaagaact tgggagcgac
    33961 cgtgtcactc tcaacttgac agaccagtac tacaatatga aagaagtcat tgaaaaagat
    34021 atgactccaa ttaccattgc taaagccgtt atggaagatc taggtatcac gcctattatc
    34081 gaaccaatcc ggggtggaac agacggctct aagatttcct ttatgggaat cccaactccg
    34141 aatatctttg caggtggcga aaatatgcac ggacgttttg aatacgttag ccttcagact
    34201 atggaacgtg cagttgatac catcattggc atcgtagctt ataaaggcta aaaagacgag
    34261 gtggctcagc tacttcgcct ttctttttat tctactggtt tttcttgatt tccagtagtt
    34321 gtagaagatt ctgttgtttc attttctgaa gttgattcag caggtttaga atctcttgta
    34381 ttgcttggtt tgttttcgtc gctagcagtt tcaatgttag attctgcagt tgcgtttggt
    34441 tggttctcag cactggtgtt atcactattt gcttcagcat ttcttgctgg acttgtttct
    34501 tcacttgcgc taacttttga ctggatttga tgattcaaaa ctagaatagc ttttgtcgat
    34561 tcaagtaaag ctgttttgtc tttactatta gcagaaagtt gatctaataa tgcatccacc
    34621 ttatcaaagt ccgcatcaga tccattatta ctttctaaat aagagtgaag cgacatgaga
    34681 atatcgtaga gtttttgata gagtacaagt gtctgagaat cttgctcagc attttccttt
    34741 tcttgttgaa gggcgctagc gatacgagtc aaaacatctt ttacctgact gtttacttca
    34801 tccaagtctg catcagcctt gtttgtggca gcttttagat tttctacttc ttctgccaag
    34861 gattgtctga ttccttcttc atggatttgt tccaagagtt gatttgcctt gttcaaaaga
    34921 ctttctactt cttccttgct atctgtcgca gattattggt tgctatctac catgtactcc
    34981 taaaacagga gagttataat ccaagattac aaggccttac agaaataaga aatccagata
    35041 agacaatgtt cgtccaagac gctattcgct tcgcacagca gcacggattc aatatgcttt
    35101 aattttaaag tttaggtgtc aagacctctt tttagtgtgc ccaaaattta gagaagtaat
    35161 caatcaacta acttttattt ttttcaaact ttcagtaaac tgacctaaag ctaactcaat
    35221 ctgtctttgt agatgcttct gctatcagct agaagttgat ctacttttgc caagactgcc
    35281 ttctcatcaa aagttccagg ttgatagttg gattgcaggg atggaatctt gtttttcaaa
    35341 gccgcttcat atcccttagt ttgaaccttg atgtagtgat tgtggtcgcc atgaggaatc
    35401 acaaaacctt ctgaatcttc acttataatt cgattggcat caaaaaccat gaccatcttc
    35461 ttcctcatgg tggacatgta gtgacggatt acttaataca gaactagaag aacttcctac
    35521 ctcttccgtg ttagagtgtg atgggggatt gttaagagat gacttaggaa tatagtgata
    35581 gtgttcccca tgtcttacta tataagcatc acctatatct ctgacaatat cattagggtt
    35641 aaagacatat gtggctgcta attcacctgc cgacaagtca ctctcaggaa tgaaatgata
    35701 gtgaccacca tgtggtacta ttagtagatt gaaatagaat atgagcaaat tgataagggg
    35761 attttaaagt aatttctaac aatgatttag aaactatgat gtgctattct aaattcaact
    35821 cactatatat aaccatcatc ggtagtataa cgtccctgta attttgctac agatacttct
    35881 gcactagctc ctttatcgtc tttaccatgt tcttgttttt ggcgattgat ttcatctttt
    35941 gttcgtacat tttctgcatg agcttgatct ttaaggtaaa cataatactt tccatctacc
    36001 ttaataatat atcctccctt aacctaactg acaatatctt gatctttcgg ctgatagttg
    36061 ggggctttca ttaatggctc ttcactaaag agcgcatcaa aaggaacttt accattatag
    36121 tagtgataat gatcgccatg agaagttaca taaccttgat ctgtaatctt aataacaatt
    36181 tgttttgctt gaattccttc tttttgacta acctagtctg gagtcaaatt ttcagtcttc
    36241 ttagtgtctt tattactgtt tacatatgaa acacgatttt tatctgtatt ggcctgttag
    36301 ctatgttggt tcagagcata aacacacaga cttaaggaaa ggataacaac agatccagct
    36361 gctatatatt tctttttaaa tttcataatt acctcatttc tataattatt tatatgatgt
    36421 cttcattatt aaatgattat agaaattaat taaccaatta attaactagt aaatattcca
    36481 cctcttttta agttgtatgt caagaaattt tatatattaa taataaaatg aaattctccc
    36541 aaagtcagag ttttatttct aacttttgag agaacttcat ttttgattca gactttttct
    36601 actgctattc cttacgctat gagatcagat aaattctttt ttatcacttc tccacttggc
    36661 aatcttaatt caatcgttcc atccatattg aatataacac tatctaagcc taatccgtaa
    36721 ctagctgtaa atttttctaa tttttcttgt acaggatcta ctgctggagc ttcctctaat
    36781 gctggatcta acatagggtc actccccaca ttcccttctg gattcaacat tccattatcc
    36841 gttgagtttt ctggttttac aggtttttcg tttggtgcct ctggtaaaga atctgctggt
    36901 ttattttctg ttggttggtt ctcaactgtt ccagtagata cttttccatt ttcagatggt
    36961 ttattttcac catttccttg aggtgcttct cctgtaaaat ctgccatatt ctttttaatg
    37021 acttctcccg atggtaaata taattcaatt gttccgtcca tattaaacaa gacattttct
    37081 agcttcatcc cataactttc agcaaatttt gctacttttt cttgtacagg atccactgta
    37141 ggaacttctt ctaacgttga attactagta ctattcccag tttcagaaag tttttctttt
    37201 tctaccttct cactagtctt tggttcttct accttttcat caagttttga gttttcttgt
    37261 gctttattcc ttttaaattg tggtagaata cttggtttat cagtttgatt ttctttttcc
    37321 aagataggta cttccacaat ataagtcgat tgattgtcca aataagcatt tgccatgaag
    37381 gttacaggaa ttttatttcc ggccgttctg gttgttcctt ggtttaattt cggaatcggt
    37441 aatttgattt caccaacttt atagttattt tctaaataag catttccatg aaattcatca
    37501 aacactctga ctaaagcatc agttccttta ggcactgcaa attgagggtt cactcttaaa
    37561 taagtatccc ctgcatggaa aggatagaaa atcgtttgac tggccatttt gtaagctaaa
    37621 gaggttggaa ctgtaaatgt accatcataa cttacttctg gataatcttt tgaagcgata
    37681 gtatacttaa atgtttgtcc tggtaaataa ggttgatcta attcaaagtt tgcaatattc
    37741 cctactcctt ctccaaatac tttaccagat actttctcca atacttttcc atctggtgtt
    37801 attaatttta ctagcatatt gatacctaat tttttctcca attcaggcgg aaaactaaaa
    37861 gaaacgcgtt tttgaccatt ggctagagta aagttttgat tattaaacgt actatttttt
    37921 aacaaattaa caacattcgt taattcttct ccagtataaa ctttattccc ttctttttta
    37981 gcaactcctt cttcgggttt aaacagttca tagttactgt gagaatgacc aattccaacc
    38041 ggtttatgtt catcaatcgg atctgcatga tggtgatctc catgcggata aataatcgca
    38101 tttttttctt tattcacgac aatactttca cgtttgacac catattgttt cataatgcca
    38161 gcaatttttt cttcgatttt tttatctaaa tctttcattt ctttggcatt acttggataa
    38221 tcctgttcat gagatgacaa agaatctaat ccattatgac tagttttaac ttcctttaaa
    38281 tgtttttgcg cagccttaat ttgctcttct gtcaagtcct tcttgaagaa ataatgattg
    38341 tggtctccgt gactcatgac aaaacctgat tcatcttcag cgataatacg attagcatca
    38401 aatccgtatc catcttcttc atgtttctca tgtgaagttc ctggattgat tggaagagat
    38461 ggagaaggtg ttgctagact attgtttgga agagtcggtt gcccaatttg atttgatttt
    38521 ggaatgtaat ggaaatgatc accatgtctt acaatataag ctgtagccgt ttcttcaacg
    38581 atatcttttg gattaaaaat ataaccatca gatgctgaag agagctcctt acttgtcgtt
    38641 aaagaagaag gattgcttga aagactgcct agactagaca ctacttcatt aggttttgca
    38701 tttgtagaaa ctgtagaacc agttccactg ataggcacca ttctggcaat cttttcttct
    38761 aaggcagaaa gcttgctgta aggaataaag tggtaatggt cgccatgcgg aatcgcaact
    38821 ccatttggtg tacgactgat aatcttagca gggtcaaaga ccaggccatc tgattcactg
    38881 taacgttggg cgctaggtga atcatagagt tccttcaaaa gactctggag attttcagat
    38941 ttatttgctg gcttgctagt tgatcctttt gctacagatt gcgtgttatt gtcactagct
    39001 gttgaagaat agcttaactg actcggttgc atattttttc cagccagatg tgctttagct
    39061 gctgctaatt cactagcaga taaatcgctt ttgggaatgt agtgatagtg acctccatga
    39121 ggaacgatat aagcattacc cgtatcttcg ataatatcag ctggattaaa gacataacca
    39181 tcatttgtcg tatatcgtcc ctgagacctt gctacagcaa cattagagtt aaccttctca
    39241 ttatctttga catgttcttg tttttgacga ttgatttcat ctttagttcg aacattatca
    39301 gcatgagctg catctttcag gtagacataa tattttccat cgaccttgat gatataacca
    39361 cccttgactt cattgacaat atcagcgtct ttaagttgat agtttggatc cttcatcaag
    39421 agttcttcac taaagagggc atcataagga actttcccat tatagtaatg atagtggtca
    39481 ccgtgtgacg ttacatagcc ctgatctgta attttgatta caatttgctc ggcctgaatt
    39541 ccttctttct ggctaatctg gtctggtgtc aagttttcac ttttctgact tgactggctg
    39601 ccatctacat aagagacacg attattgtcc ttattttcct gcgaacgatg ctggtttagt
    39661 gcataggcac atagactcaa ggatacgata acagctgatc cagctgctat atatttttta
    39721 ctgaatttca taaatccctc atttcaataa atgatgaagt tttttctcaa cttcttttac
    39781 tttattaaat agttttctaa accggttatt taaccattta attaaccagt aaatagttta
    39841 ctatttaaaa ttacttttgt caagtttctg ttacgttttt ctaaaaaaga gaagtaacac
    39901 gaaaggttac ttctccataa aatatgctcc attcatttta ctactgtata ggagtcggtt
    39961 gactttcttt taacaaagcc aagagactat ctacttctgc tgaaatagtg ttattatctt
    40021 tcgttccgag aagaagacta ctttttagac cagtcaatgt ctccacagca ttttgtctaa
    40081 tactagaatc tgttactttt tctagcaagg cctccgc
//
LOCUS       DAYYYC010000015        38283 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.015, whole genome shotgun sequence.
ACCESSION   DAYYYC010000015 DAYYYC010000000
VERSION     DAYYYC010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38283
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.015"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(<1..1339)
                     /gene="rlmD"
                     /locus_tag="ACHBV5_000818"
     CDS             complement(<1..1339)
                     /gene="rlmD"
                     /locus_tag="ACHBV5_000818"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFM9966650.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVK"
     gene            1377..2153
                     /gene="recX"
                     /locus_tag="ACHBV5_000819"
     CDS             1377..2153
                     /gene="recX"
                     /locus_tag="ACHBV5_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFM9966651.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2242..2775
                     /locus_tag="ACHBV5_000820"
     CDS             2242..2775
                     /locus_tag="ACHBV5_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFM9966652.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(3130..3561)
                     /locus_tag="ACHBV5_000821"
                     /pseudo
     CDS             complement(3130..3561)
                     /locus_tag="ACHBV5_000821"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(3648..3986)
                     /locus_tag="ACHBV5_000822"
     CDS             complement(3648..3986)
                     /locus_tag="ACHBV5_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM9966653.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADFISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEYYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKKLIK"
     gene            complement(3999..4772)
                     /locus_tag="ACHBV5_000823"
     CDS             complement(3999..4772)
                     /locus_tag="ACHBV5_000823"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM9966654.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(5218..5973)
                     /locus_tag="ACHBV5_000824"
                     /pseudo
     CDS             complement(5218..5973)
                     /locus_tag="ACHBV5_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(6111..7733)
                     /gene="groL"
                     /locus_tag="ACHBV5_000825"
     CDS             complement(6111..7733)
                     /gene="groL"
                     /locus_tag="ACHBV5_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFM9966655.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(7749..8033)
                     /gene="groES"
                     /locus_tag="ACHBV5_000826"
     CDS             complement(7749..8033)
                     /gene="groES"
                     /locus_tag="ACHBV5_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFM9966656.1"
                     /translation="MLKPLGDRVVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(8303..8698)
                     /locus_tag="ACHBV5_000827"
     CDS             complement(8303..8698)
                     /locus_tag="ACHBV5_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFM9966657.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(8776..9537)
                     /locus_tag="ACHBV5_000828"
     CDS             complement(8776..9537)
                     /locus_tag="ACHBV5_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFM9966658.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(9570..10196)
                     /gene="ytpR"
                     /locus_tag="ACHBV5_000829"
     CDS             complement(9570..10196)
                     /gene="ytpR"
                     /locus_tag="ACHBV5_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFM9966659.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFEIAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(10212..10529)
                     /locus_tag="ACHBV5_000830"
     CDS             complement(10212..10529)
                     /locus_tag="ACHBV5_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFM9966660.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRVDRDQYIDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(10526..10825)
                     /locus_tag="ACHBV5_000831"
     CDS             complement(10526..10825)
                     /locus_tag="ACHBV5_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HFM9966661.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            10919..11050
                     /locus_tag="ACHBV5_000832"
     CDS             10919..11050
                     /locus_tag="ACHBV5_000832"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966662.1"
                     /translation="MKIKDQTRKLAAGCSKHCFEVVDRTDEVSSKHCFEVVDEADVV"
     gene            complement(11075..11272)
                     /locus_tag="ACHBV5_000833"
                     /pseudo
     CDS             complement(11075..11272)
                     /locus_tag="ACHBV5_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724444.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(11514..12188)
                     /locus_tag="ACHBV5_000834"
     CDS             complement(11514..12188)
                     /locus_tag="ACHBV5_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966663.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            complement(12194..12640)
                     /locus_tag="ACHBV5_000835"
     CDS             complement(12194..12640)
                     /locus_tag="ACHBV5_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HFM9966664.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(12754..13257)
                     /locus_tag="ACHBV5_000836"
     CDS             complement(12754..13257)
                     /locus_tag="ACHBV5_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFM9966665.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(13254..13616)
                     /locus_tag="ACHBV5_000837"
     CDS             complement(13254..13616)
                     /locus_tag="ACHBV5_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HFM9966666.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFLQAPYYVPERIAITGKICGVHIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(13682..14713)
                     /locus_tag="ACHBV5_000838"
     CDS             complement(13682..14713)
                     /locus_tag="ACHBV5_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFM9966667.1"
                     /translation="MGFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSVTAHAGQRVAIVGPTGAGKTTIVNLLMKFYEIDKRSIRI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIACALLKDASLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSIIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            complement(14720..15541)
                     /locus_tag="ACHBV5_000839"
     CDS             complement(14720..15541)
                     /locus_tag="ACHBV5_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9966668.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQETNLDELWQPA
                     SMMMGMSFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLT
                     RTTNDITQVQMLITMGLQVVTRGPIMAIWAIGKILGHSEYWLWAVLVVVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIIFMSYAM"
     gene            complement(15558..16029)
                     /locus_tag="ACHBV5_000840"
                     /pseudo
     CDS             complement(15558..16029)
                     /locus_tag="ACHBV5_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            complement(16153..16869)
                     /locus_tag="ACHBV5_000841"
     CDS             complement(16153..16869)
                     /locus_tag="ACHBV5_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM9966669.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(17750..19165)
                     /gene="ply"
                     /locus_tag="ACHBV5_000842"
     CDS             complement(17750..19165)
                     /gene="ply"
                     /locus_tag="ACHBV5_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HFM9966670.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(19176..19586)
                     /locus_tag="ACHBV5_000843"
     CDS             complement(19176..19586)
                     /locus_tag="ACHBV5_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966671.1"
                     /translation="MIKRGDVVALYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTVIPTSYLARRRRN
                     VSEELYEEILDHLVQPRLISLNKSEFMQLNPGTY"
     gene            complement(19579..20187)
                     /locus_tag="ACHBV5_000844"
     CDS             complement(19579..20187)
                     /locus_tag="ACHBV5_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966672.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(20200..20658)
                     /locus_tag="ACHBV5_000845"
     CDS             complement(20200..20658)
                     /locus_tag="ACHBV5_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HFM9966673.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            20783..21182
                     /locus_tag="ACHBV5_000846"
                     /pseudo
     CDS             20783..21182
                     /locus_tag="ACHBV5_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(21947..22207)
                     /locus_tag="ACHBV5_000847"
     CDS             complement(21947..22207)
                     /locus_tag="ACHBV5_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966674.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFFDG"
     gene            complement(22266..22817)
                     /locus_tag="ACHBV5_000848"
     CDS             complement(22266..22817)
                     /locus_tag="ACHBV5_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966675.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(22807..23004)
                     /locus_tag="ACHBV5_000849"
     CDS             complement(22807..23004)
                     /locus_tag="ACHBV5_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966676.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(23008..23802)
                     /locus_tag="ACHBV5_000850"
     CDS             complement(23008..23802)
                     /locus_tag="ACHBV5_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966677.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(24210..24635)
                     /locus_tag="ACHBV5_000851"
     CDS             complement(24210..24635)
                     /locus_tag="ACHBV5_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966678.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDNNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(24764..25123)
                     /locus_tag="ACHBV5_000852"
     CDS             complement(24764..25123)
                     /locus_tag="ACHBV5_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFM9966679.1"
                     /translation="MKKSSVSLILIGEGDETERKADQLASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMVLG"
     gene            complement(25169..25375)
                     /locus_tag="ACHBV5_000853"
     CDS             complement(25169..25375)
                     /locus_tag="ACHBV5_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966680.1"
                     /translation="MDLSNKASNLRKKLGADGEAPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(25362..25535)
                     /locus_tag="ACHBV5_000854"
     CDS             complement(25362..25535)
                     /locus_tag="ACHBV5_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM9966681.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLYLSLNQSMIAK
                     MEKGERNITNGFK"
     gene            complement(25894..26850)
                     /gene="lytA"
                     /locus_tag="ACHBV5_000855"
     CDS             complement(25894..26850)
                     /gene="lytA"
                     /locus_tag="ACHBV5_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HFM9966682.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADRPEFTVEPDGLITVK"
     gene            complement(27226..28596)
                     /locus_tag="ACHBV5_000856"
     CDS             complement(27226..28596)
                     /locus_tag="ACHBV5_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFM9966683.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSTFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(28910..30076)
                     /gene="recA"
                     /locus_tag="ACHBV5_000857"
     CDS             complement(28910..30076)
                     /gene="recA"
                     /locus_tag="ACHBV5_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFM9966684.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(30131..31387)
                     /locus_tag="ACHBV5_000858"
     CDS             complement(30131..31387)
                     /locus_tag="ACHBV5_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFM9966685.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(31472..32488)
                     /locus_tag="ACHBV5_000859"
     CDS             complement(31472..32488)
                     /locus_tag="ACHBV5_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFM9966686.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(32496..33014)
                     /locus_tag="ACHBV5_000860"
     CDS             complement(32496..33014)
                     /locus_tag="ACHBV5_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFM9966687.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(33004..33447)
                     /gene="tsaE"
                     /locus_tag="ACHBV5_000861"
     CDS             complement(33004..33447)
                     /gene="tsaE"
                     /locus_tag="ACHBV5_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFM9966688.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(33533..34153)
                     /locus_tag="ACHBV5_000862"
     CDS             complement(33533..34153)
                     /locus_tag="ACHBV5_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966689.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(34536..35399)
                     /locus_tag="ACHBV5_000863"
     CDS             complement(34536..35399)
                     /locus_tag="ACHBV5_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM9966690.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            35591..35761
                     /locus_tag="ACHBV5_000864"
     CDS             35591..35761
                     /locus_tag="ACHBV5_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="HFM9966691.1"
                     /translation="MRKKRGIKKLVTFALLGVFMFSNTIPYQQFIQKNKQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            35864..36088
                     /gene="pneA1"
                     /locus_tag="ACHBV5_000865"
     CDS             35864..36088
                     /gene="pneA1"
                     /locus_tag="ACHBV5_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HFM9966692.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKVCISAAVSGIGGLVSYNNDCLG"
     gene            36095..36283
                     /gene="pneA2"
                     /locus_tag="ACHBV5_000866"
     CDS             36095..36283
                     /gene="pneA2"
                     /locus_tag="ACHBV5_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HFM9966693.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
     gene            36399..>38283
                     /gene="lanM"
                     /locus_tag="ACHBV5_000867"
     CDS             36399..>38283
                     /gene="lanM"
                     /locus_tag="ACHBV5_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="HFM9966694.1"
                     /translation="MKYKIKNVHKTLFIKERYQILSERNDNSLNNFSLNNWRSTMSII
                     SEKTFEEMLKLNNYNKKIFSNTVNYDYTEEQIRLYSEYAKNSEWYKFAEGSFEIFRKH
                     PQRINFKKDFSRILEPFIINLLKLINNYLENKEYEWIDKNGNIFSSLVFYLEDLIYPW
                     IVKPLVLEINSLREKGLLEGESEQQRYKYFITLFDKEENILNFYNKYPVLLRQISESC
                     LRFYTYFIEILSNLENDFSVLEEELGLRGKLNDIKFGKGDTHSQGKTVLILFFDDAKI
                     VYKPKNLIINNSLNTIAEYIRKVDEKIRIRIPRTIAYSDHSYEEFIDYLPLEQKKNLP
                     EYYYNFGVLLAFIYLFNGSDIHFENLISYGDMPVIIDFETMLQQPLFDDKTGQSLLDT
                     LFHRVTRTLLLPTEGVKREDGLDVEMSALTGNFKKDAFNGQVLINLNTDKVKFDIGKI
                     DFEGGKNLPVRDGDIEFDKYIKDFKKGFRDFYLIFEELNKTEEFKMLLKANLYGLKTR
                     VLFRDTNSYASVLSFLYHPDFYEEMLDREKALENLWSNKFSNQGIVASECEQMRLLDI
                     PIFYTDTNINEIYDDFGNHFISLHQFSGYDYFMKYLPNNNLENLEKQLDIIEIYFPSF
                     DQRK"
BASE COUNT        11841 a         7962 c         6479 g        12001 t
ORIGIN      
        1 attttacaac agcttcagtt cgagctgtat gtgggaacat atcgaccgac tggatataat
       61 gaagatcata gacttctact aagcgtacca aatcacgagc caaggtcgaa acattacaag
      121 aaatataaac cattttttct ggtacataag taagaatagt atctaataac ttatcatcca
      181 gacctgtacg tggtgggtca acaatcaaag catctgctcg gtagccttcc ttgtaccaac
      241 gaggaataat ctcttctgcc gttccagctt cataatgagt attgtcaaat cccattcttt
      301 tagcatttcg cttggcatct tcaatagctt ctggaataat atccatacct ctgagtgttt
      361 ttactttctt tgcaaaggca aatccaatcg ttccaactcc acaataagcg tcaatcaaat
      421 ggtcttcttt atcaacatcc agcgctttta ctgcttcgct atagaggact tctgtttgct
      481 caggatttag ttgataaaaa gctcgagggg atagtgaaaa ttcataattg agtacacctt
      541 cttgaatact ctcttgcccc cagataatct ctgtcttttc accatatatc tcactggttt
      601 tagctgtatt tgtattaaca gctactgtca caacttctgg gaaatcttta accaactctt
      661 ttaccaattg agttaaatta agctggcggt ttgtaacaat aataatctga acctgtccgg
      721 tctttctcgc gcgtcggacc ataatagtac ggacacctag aacttttctc tcatccgtga
      781 ttggaatctg gtgataagta agtaattctg ctaagcgatt agcaatcact tgggtttcct
      841 tatcttgtac caggcagtct ttcaactcta ctaaatagtg agagttttgt gcatataagc
      901 ccgccttgac ctgattttta aattttcgag tctgaaattg taacttagct ctgtaatatt
      961 ttggttcctg cattccaata gttggacgaa tttcataatt ttcatatcct gcaggagcaa
     1021 attttttcag cgcttgatga agtaagtccg tcttgaactc cagctgctta tcataatgca
     1081 ggtgcatgat ttggcagcct ccgcattcat tataaatagt acaagatggc acaattcgaa
     1141 atttagactt cttgttgacc ttcagtaatt ttgcttcaac aaagttgcgt ctaatagaag
     1201 taatctgaca atagatatct tcgcctttga gagctccagg tacaaagact aatgtttttt
     1261 ggtaaaagcc gattccctca ccattaattc ccatgcgttt gatttttaat ggtatttttt
     1321 gtttcacttt cagattcata cccctatctt atcacatttt gagttataat agagctatga
     1381 aaatcacaaa acttgaaaag aaaaaaagac tctatctgat ggagcttgat aatggcgaca
     1441 aatgctatat caccgaagat acaattgttc gttttatgtt atcgagagat aaggtgataa
     1501 gcgaagagga attgaaagag attcaagact ttgctcaatt ttcttatggt aagaatctgg
     1561 ccctctacca cttatccttt aaagcacgca ctgaaaaaga agtcagagaa tatctgaaaa
     1621 aatacgatat tgatgaaaac atcgtttctc aagttattgc taatcttaaa gaagataagt
     1681 ggattaatga tggtcagtac gcttatgcta tcatcaatac caatcaactt tcaggagaca
     1741 agggtcctta tgtgctgact cagaaactag ctcaaaaagg gatttcaaaa tctactatag
     1801 aagagaactt gaaagaattt gatttttctg aagttgctca acgtgtagcc aataaactat
     1861 tgaaaaaata tgagggaaaa cttccagctc gtgccctgca agataagatt atccagaact
     1921 tgactaacaa gggcttctct tattctgatg ctaaaattgc ctttgacgac ttagatagcc
     1981 aagttgacca agaaacgact caagaactca tcttcaagga acttgataag caatatacta
     2041 agtatgctcg aaagtatgaa ggatacgaac tgaagcagcg tttaactcaa gttttagcac
     2101 gaaagggcta cgatttttcg gatatagcaa gcgctcttag agaatatctt taatatttcc
     2161 aagtgaaatt cacagatttt aggtaatttt atggtacaat agtaaatgat aaacttataa
     2221 attgtagaaa gttggttagt tatgaagctt ccaaaagaag gcgactttat tacaattcaa
     2281 agttataagc atgatgggag tctccaccga acttggcggg acaccatggt actaaaaaca
     2341 acagaaaacg ccattattgg tgtcaacgat catacacttg ttaccgaaag tgatggtcgt
     2401 cgttgggtca ctcgagaacc ggctattgtt tactttcaca agaaatattg gtttaatatc
     2461 attgccatga ttcgtgataa tggaacttct tactattgca atatggctag cccctactat
     2521 ctggatgaag aagcactgaa gtatattgat tacgatttgg atgttaaaat ttttacagat
     2581 ggggaaaaac gtctcttgga cgttgaagag tacgagcgtc acaaacgcaa aatgaattat
     2641 tctgatgact tggactatat tttaaaagaa catgtcaaaa ttcttgttga ttggattaac
     2701 aatggacgtg gtcctttctc agaagcctat gtaaacattt ggtacaagcg ctatgtagaa
     2761 ctaaagaatc ggtaaagttg tcaaaggtca ggaacaaaat cctgaccttt ttttggtagt
     2821 ataaaataaa ttgtgtaaac acaaaaagga ataaatctat tatagcagag ttacaacaca
     2881 ttactagaaa gagatttatg caaaattcgt aaaatatata aaacaaatag atatactgtt
     2941 attttttaat gtctttattc cttgtaagtt tacaacaaac ttatatcgtt taatacaaaa
     3001 aatacgaaaa tgattagtat aaaaaataca ggtcaacttc gtatcaaaaa catttttttg
     3061 tatttccaca tagcatcaat catttagtac aatattttaa aaacaatatc ttaacagaga
     3121 aaatgatatt taatctatca gctcatttaa tcgtttttga aaatataaag caatactttt
     3181 agattcaata aactcaaaat attttatgac attgtccatt tgtttaattc cagattcttt
     3241 agattctgtc aggtatattt tatatccttc tacaaatttg aatgtagatt tttcaaaaac
     3301 ttttgtgtca tcttttaata atttttgtaa tttcatttca aagtagtctg catatattag
     3361 atgtgaattt tcaaggcaac agaaccaaaa atttaaacaa gctgacacaa ctaaatttct
     3421 attcttgccg attttttcgt aataatgtgt acgctctagt atttcttttc cgaccatgta
     3481 aatataatct atttcaaaaa gatgatataa attaccaatc agcgttatct cataggactc
     3541 ccatcgttcc ttctggaata aatagtcata tactaaattt agatcatctc tactaactac
     3601 atgattacaa tctagctgat ttcataatcc ctgaaccata attgtattta ttttatgagt
     3661 tttttcccac tcttctcaaa aagtttttgt tgcttatttt ttattacctc caatccttta
     3721 atattcaaac tataaaaatt tggagataaa ttaaccaaaa aatcatcacg ctccgatctt
     3781 ttataatatt ctaagtgatt acaaaaattc tctatcgaaa cattgatatt tgataataat
     3841 tcaaaaaatg ttgaaagaga aatttcattt tctccccttt caaatctaga aagttgagat
     3901 tttgatataa aatcagctgc agcatactct aaagaatatc cgtttaattt tctaaaatat
     3961 cgaaaagctt ctccgtaatt tttcacactt tcattccctt aactttcttt tcgagcgata
     4021 aacataccat attctttagg aatgatcaac ataccattat taaactcact ttccaatctt
     4081 ttacgtatta tttcctcttc tagtgaacct atttctgaaa ttcctttaaa cgattggatg
     4141 tatttaacta ggtcatctat actagttacc tgtaactcat catcatagag taatgtatcg
     4201 acagagttaa aatacctact caggtacctt ttaccatttt gtaaagtaaa cgttctattt
     4261 tctaaatctt gattaacctc atctttaaat aaacttgcca aataatttac aactccattt
     4321 tcaccaaatg tagcacagta aaaaatgcct ccggttttta agaccctatt cacctcagag
     4381 agagctttag gaatatcatt cacatgatgt agaagcatat tagcaataac aatatcaaaa
     4441 gtttcattct caaaagaaat cttttgaata tccattatct cataattgac attgtttcta
     4501 tttccaatca ctgacttcgt tgattttacc atatctttag aaaaatctgt aacaatcaac
     4561 tgcttcattt tatctataga atcactatta cttttccaca attctcctgt accacatccc
     4621 aattctagaa cctttacttc atcagtgatt tggtagttag aaaatatcca attattaaat
     4681 cccaatttat tttttgaata cttcttatgc aattctactc gaatatcaag attatcatga
     4741 cttttatatt gttcaattac tttatcaatc attttaaatg acctccactc tataatttgg
     4801 cattatatca caagaataaa gatagtgtta aataagttat ataaatgcaa aaaaggaata
     4861 ttccgttata gcagagttgt aacacatttc tataaagaaa tttattccta cgactcagtt
     4921 tggcatgctt aacttcctaa ctcaaaaaca aagcatcgat taatttatcc gttcttcttt
     4981 tgaaacagat ttgaactgat aattgctcgt tttaatttaa aaagctcttt tgagcaaaac
     5041 ttcatttttt taagagtcca acaatttctg tctatcgctt ttctactagc aaaaaaccta
     5101 ccttgaggca agttttcatt tatatatcta atttcgtaac agtatagtaa aatgaaataa
     5161 ggacagtcaa atcgatttct aacaatgttt tagaagtaaa ggtgtactat tctagtttca
     5221 atctactata aatttgatat gagaatagtc tttctcaaca tccttatcca acaagcatgc
     5281 tgtggcgtcc ttcttaactt aaaccaggtc aatattctgg gcttgggctg catagacgca
     5341 gccacaataa cattgacgat agatatcata ctcctcacac atctctactg aacgtttgta
     5401 gccttgattt ttcttgaaat cgttgggaag atagtggggc gtgtaaattt tttgcacatc
     5461 gattccgatg ctattgatag tttgagaatt cttatgagga ctgatggtca aggctgaacc
     5521 aaagtagtca aagcccaagt ccatagccac ttgcgctgtt ttatccagtc ggtagtcaaa
     5581 acaaaccttg caacggtcgc caccttcggg ctcctcctct agccccctaa ctagttttcg
     5641 gtattaattg ggttcgtagg gagcttctag gtactgaacc gtatttcctg tccgctcatt
     5701 aaaatcacta acaaatttct tggtgacata gacccgctta tggtattctg ccttgggatg
     5761 gatattagaa ttggcaaaat agatggtcac atctgcatac ttggtcaaat attctagtgt
     5821 ataggtacta caaggggcac agcaaacatg cacgagaatg gttggccgct actcattttt
     5881 ttcccatgct tgtaccattt tctgcatgac acggtcataa ttaatcttct gattgggggt
     5941 catcttgcac agaatttctt ctacatcgat catgttcttc tcctttttct agtcttattt
     6001 tatcatataa gttaggagag ctcaaatcaa tttagaagtg aatattataa aaagaagggt
     6061 tagtcattcc ctccttttgt gttttttata agttgttttc tatagaaagc ttacatcatc
     6121 ccgcccatca tacttggatc cattgctgga gctggggcta ctggttctgg tttattggct
     6181 acgactgctt ctgttgtcaa aatcaagctg gctacagatg ctgcattttg tagggctgaa
     6241 cgactcactt taactggatc aatgatacct tgatcaatca tgttaaccca ctcgccagtt
     6301 gctgcgttga atcctatacc aagctcagca tttttcaaac gatcgataac gatagatcct
     6361 tcaaatcctg cattgtgagc aatttgacga acaggttctt ccaaagcacg gagaacaata
     6421 ttacgtcctg ttgcttcatc tcctgtcaat tccaaggtag caacagctgg aatcacattg
     6481 gcaagagctg ttccaccacc tgcaacaata ccttcttcaa cagctgcacg agtagcgttg
     6541 agggcatctt caatgcggag tttcatttct ttcaactcag tttcagttgc ggctccgacc
     6601 ttaataaccg ctacaccacc tgacaatttg gccaagcgtt cttgcaattt ttcacggtca
     6661 aattcagaag ttgtagtttc gatttgagac ttgataaccg caacacggtg agaaatcgct
     6721 tcaggatttc ctgcaccttc tacaataacc gtgctatctt tgtccacggt cactctcgct
     6781 gcttgaccaa gagcttcaat tgtcgcatct ttcaactcaa gaccaaggtc ttctgtgata
     6841 actgttccgc ctgttaagat ggcgatatct tcaagcatgg ctttgcgacg gtcaccaaaa
     6901 ccaggtgcct tgactgctac tacgttgaag gttccacgaa tcttgttcaa aacaagagtt
     6961 ggaagagcct cgccatccac atcatccgca ataatcaaga gtggacgatt gctttggaga
     7021 atgctttcca aaagtggcaa gatttcttgg atattggaaa ttttcttgtc tgtaatcaaa
     7081 atgtacggat tttcaaggtc agccaccatt ttttcgctat ctgtcaccat gtactgtgaa
     7141 aggtaaccac ggtcaaactg cattccttct acgacttcaa gctctgtttc cataccacgt
     7201 gactcttcga tggtgatgac accgtctttg ccaacttttt ccattgcttc agagatgtac
     7261 tcaccaactt tttcagaacg agaagatacg gctgcaactt gagcgatagc ttctttattg
     7321 gcaacaggga tggcgttgtt tttcaaagct tcaactgctg cggcaactgc tgtttcaatc
     7381 ccacgacgaa taccgattgg atttgcacct gctgtgacgt ttttgattcc ttcacggacg
     7441 attgcttggg tcaaaacagt tgcagttgta gttccatcac ctgcgatatc attggttttt
     7501 gaagctactt ctgataccaa tttggcaccc atattttcaa aatggtcttc taattcaatt
     7561 tctttggcaa tagtcacacc gtcattggta atcaatggtg agccaaatga tttttcaaga
     7621 acgacattgc gaccttttgg tcccaaagtt actttaacag tatctgcaag gatatcgaca
     7681 ccacggacca tggctgaacg ggcatctgat gaaaatttaa tttcttttga catacttact
     7741 ttctccttct attcttcaat gattgccaag atgttagctt cgcctacgat gatgtacttt
     7801 tcatcgccat ctttgacatc aagacctgcg tgggcttcaa ctaagacacg gtctccagtt
     7861 ttaacacttg gagcaaccaa gtcaccgttc aaggtacgaa caccttgtcc agtagccaca
     7921 acttgggctg ttttggtttt ttcttgggct gaacctgcga gaacaaagcc tccaacagtt
     7981 tgttcttttt cttctacttt taagaccaca cggtccccta atggtttcaa catctgattt
     8041 cctccataat gagatagata ttattagcac tctttatacc tgagtgctaa ttcatagttc
     8101 tattgtatca cttagtcaga aataatcaag aaaaaagtct gactttctca agataaaaag
     8161 cctgagacca actcagactt tttaatgttt atactcaatg aaaatcaaag atcaaactag
     8221 gaagctagcc gcaggctgct caaagcattg ctttgatgtt gtggataaag ctaacgtggt
     8281 ttgaagagat tttcgaagag tattaaaatg gcaattcttc ctcttccaag actaaatctg
     8341 ccaaatcttg gcctgcatta ttttcacgca tggcacgttg agcacgactt tccaagagtt
     8401 ggaatcctgt tacaagtact tcggtcacgt agttcatttg gccatttttc tcaaagcgac
     8461 gggtacgcaa ttctccatca acggaaatga gactaccttt ggttgcgtag cttgccaaag
     8521 tttctgctag tctgccccat aggaccatat tgacaaaatc agcttcacgt tcaccgtttt
     8581 ggtctttgta acgacggttg acagcgatag ttgctcgcgc taccgacttg tcattgttgg
     8641 ttttgtgcaa ttctggtgta gacgttaaac gcccaatcat gataacttta ttatacatat
     8701 tttcttcctc ctacttatct attcgtagga aatcaaaaaa agttacagaa atttgtaact
     8761 tttcgaggaa atttcttatt ttttatgaat catgaaacct gtcgcctgtt gattggccat
     8821 aatggtcata tctgtaatct gaacacggcg aggctgactg gtcacataga ctactgtgtc
     8881 tgcaatatcc tgagcttgca aggcttctat tccttggtaa acggacgcag ctcgctcttt
     8941 atcaccatga aaacgaacag ttgagaaatc tgtttcgaca atcccaggct gaatggttgt
     9001 caccttgata tccgttgcga tggtatcaat tcgcagtcca tccgaaaagg tcttaaccgc
     9061 agccttggta gctgagtaaa cagcggcacc agcataggcg tagattcctg cggttgaccc
     9121 catattgata atatgacctt gattgacttt tatcattgct ggcaagaaac agcgagtaac
     9181 cgccatcaga cctttaacat tggtatccaa catggtcaac atatccaact cctcatagtc
     9241 ttgataggga gccaagtcaa gagccagtcc ggcgttgttg accaagatat caatcctccc
     9301 tatcgtttct agaatatcag agcaaacagt cttcaccatg accatatccg tcacatctag
     9361 tggaaaagtc cagacggttt gatttggaaa gcttactgca aactccgact tgaggatttc
     9421 taatctgtct atccgtcgtc ctgttagaac gacatcctca ccctgctcca gataagcacg
     9481 cgcaatcgct tcaccgattc ctgaggttgc tcctgtaatc actacatttt ttgccatctt
     9541 atttccttct atcagatgct gacaagttcc taggcagtcc agtgtttcgc tgggtcgaac
     9601 ggtgttccga caacttggtc ttctgataat tcaagcaccc cacgtttttg tggagcattt
     9661 ggcagatgca attcacgagg actgcacatc ataccaaaac tcttttcacc acgaagttca
     9721 cctgggaaaa tgagattccc ttttggcatc atagctccag gaagcgcgac aatggttttc
     9781 aaccccacac gcgcattggg agctcctgca acgatttgta cagtcttatc acttgcgact
     9841 gcaacttggc agatgttgag gtggtcacta tctggatggg ctaccatctc aacaatttca
     9901 ccgacaacaa acttaggttc cttatcatta acaatttctt ctgtaaaacc ttccgcctgc
     9961 aactcttggt tcaaacgagc gacttgctca tctgtcaaaa agacttgacc gcgctctgca
    10021 atttcaaata aacttgaaac ttcgaaaata ttccaagcca ctgtttcccc attatctttg
    10081 agaaaaacac gggctacctt gcctttgcgc tccacatcca gtttggcatc tccgctattt
    10141 ttcacgatga ccataaggac atcaccgaca tgttctttat tatatgtaaa aatcattgtt
    10201 tcctttttct cctatttcag tcctgctaaa aagtcattga tttgttgctt gcttttacgg
    10261 tcgcgattga caaaacgacc gatttccttg tccttttcta gaacaacaag gctagggatt
    10321 ccatatacat cccagagttt ggccaaatct atatactggt ctctatccac tcgaataaag
    10381 gtaaactctg gattagtctc ctcaatttct ggtaaggcag gatagatata acggcaatcg
    10441 ccacaccagt ccgccacaaa aaggaagacc ttcttaccgt ctttttctac taaagatgcc
    10501 aattcttcta aacttgctgg ttgtatcata agacttcctc ctcatagact aggtcttcat
    10561 tttcatagac aaaagtataa tgacggccat cctcaaaaat gacgccacca agcaagctct
    10621 ctagactgct ttcatagact tgaacataga gggtcgcaat ttcccccatg tctgaaaaat
    10681 ggtctcgtac aatcgctgtc aactcttcct gagtcttcat gagcttatgg tcatctgcaa
    10741 cttttttcgt agcaagggca aggctcccaa taccaagcag agccagacct gccatccaca
    10801 tttttttagc tttcatacca ttcattttaa cacaaaaaag gctttaggac aaatgaggaa
    10861 acagcaaaaa agcaagtaaa aagcctcttc ctttaaggaa aaggacttct tatactcaat
    10921 gaaaatcaaa gaccaaacta ggaagctagc cgcaggctgc tcaaagcact gctttgaggt
    10981 tgtagataga actgacgaag tcagctcaaa acactgtttt gaggttgtgg atgaagctga
    11041 cgtggtttga agagattttc gaagagtatt attcttattg ccaggcgcct gagttaccaa
    11101 cgtagtaacc atcaggtgtg taggtattgc gaagcatctt acctgatgaa gctagataat
    11161 accacttgcc attatctttg acccaatcat tcgctagcat ggctccagaa gaacttacat
    11221 aataccattc tcccttgtca taaacccaag tgcttgcttt catggctcct gagcaattaa
    11281 aggttcaaaa aactgtccaa tatcattcat ttttttaaag cattttacac tacatcatcc
    11341 acgctgtagg acatagatac atcaaacgta agagccaaaa tatcgaaaaa tatacaactt
    11401 ttaaaggcaa catttcattt tttaaagtct aacaaccata gaactgaaat cagagcaagg
    11461 catcaacttc ctactcttag tacgtctatt ttgatggttg aagtgaagat tttttattta
    11521 acgtagacaa gctccaactt cccaaaagcc acatctccac ggataatcaa ggttttgctg
    11581 gttggggcta caggagcgtc agccttagct gcaccaaagg aggtttctac tttcaaatct
    11641 acacgccagt gttgtggaac atagacggtt gcattcccga aggccacttc aatatttaaa
    11701 gttgcaaaat cacctagcat ctctgcatta tcatagtaga ttttagcatc cccaaaagcg
    11761 acttccactt ggtcatctac gagatcttga tcttgcttat agaaggtccc gctaccaaaa
    11821 gcgacttcct tatccgtgac gactgttttt ttcccattgt accaccattt tttttcattc
    11881 cagaacttac ttgaatgcgt cagataacca acaccaagta ccaccaagat gctagcccaa
    11941 ataagagaat gattggtaac tggtaacaag tcataagcgt aatttgcaat gatgagcgcc
    12001 agtaaacctg taaaaactgc cgaagtgaga tgacgtctaa ggatggactc aatggactta
    12061 taagcaaaaa aaacaatacc tagtaaaggc catattttac catccaaaga aggaattcca
    12121 aaattccctt gcagcaagat ccaagctgct aaaaccaata aaacaatacc aaatgctttc
    12181 tttttcatgt tttttacctc atgtttctta gattttcttt taggagggat tggtaatgcc
    12241 gtgagacatg aacctccttg tgcgtctgat aaaaggaaat ggtgcccgtt cctgaaaagg
    12301 acttgtccac tgagtaaatc tgacggatgt ttgcgatcgt tgacttggaa actcgattaa
    12361 aatagcgagg caagatagac tccaactcat agagcttgag gcgaacctca taagcttcct
    12421 tctggttatg agcgtagatc ttgctccctt ctgtttcaaa gaagagaatt tctgacaggt
    12481 ctagataata ttcacctgtc cccttgtaaa aagtcaacct cggagccttt gactcttgca
    12541 agagccgttg caagtctgca atttcatctg tcaaagtggg ggtcttgatg acaatttcag
    12601 tctcctctaa attgccgtca atctcaattc gtaacttcat cacatctcct ttctgactct
    12661 actatatcaa agctaagtta ggaatacaag ggcaaaaaag caagtggtca atttgaagca
    12721 gtaagtggtt gtaggactag cttaacttac atgtcagaat aggaagaaaa ggaatcccca
    12781 caccagacca caagcatagc caaccaagac atccttggga taatgaacac cccctaaaac
    12841 cctcaccaac cccagcaaag ctgaaaagat caagcatact aagccaatag gtagactagc
    12901 atgcagacag gccatggaga tgatagttgc agaaaagaca tggcgactgg gcatcgaccg
    12961 tcccgaacta tccttatcaa gaaggggaca gatatcccaa gtttcataag gtctcgggtg
    13021 attgattttc ttacgaaaca gggacaaggc cacaaaacct gatgcaggaa taagcacata
    13081 aaccccaact tgctgaccaa gtcctagttg caggtaagtg gtgactagca agatcagata
    13141 gaccaggggc atggcgactg tcatcaaacg attgaaactg cgtaatagga ataaaagaat
    13201 tggacgacta gttagtctgg agctgatatt tcgataccat tcttgataat ttttcattta
    13261 tgcttctcat acttttctag aacttgttga gatgttttcc ccttggcaag ccaatccact
    13321 agcttgtcca aacgacgtat ttcctgcatc agaggatcat caatttcctc aatatggaca
    13381 ccgcaaatct tccctgtaat tgcaattcgt tcagggacat aatatggtgc ttgtagaaaa
    13441 aaatctccgt aagtaacatc cctatccaga caagcaagaa cgtcactcac ttcataccct
    13501 gtcaaccaac tggtcacttg gtgaactgac tctgcctttc caccctttcg ctcaactttt
    13561 gcaatcaagg ctaagtagac agcagcaaat ttcatattgt ataatttctg actcatactt
    13621 ctctctttct atgtgtacta gtataaataa gaaaaagaag gccgtcaagc ctttttttga
    13681 tttattcttc tgcttcatct tctgtaaatt gactattgta caagtcagcg tagaagccac
    13741 cttgcgccat cagttcctca tagttgcctt gctcgatgat atttccatct ttcatgacca
    13801 agatcaagtc tgcatttcgg atgattgaca agcggtgggc aatgacaaag gatgtgcgtc
    13861 cttccatcaa acggtccatg gctttttgga tcaattcctc tgtccgtgtg tcaacagaag
    13921 aagtcgcctc atccaaaatc aaaagcgatg catccttaag aagggcacaa gcaatagtca
    13981 atagttgttt ttgtcctaca gacaaggtca cggtgtcatc caagatggta tcatagccat
    14041 ctggcaaggt cataataaag tggtgaattc ccacagcctt actagcttcc atcattcgtt
    14101 catcactaat ccctatttga ttatagatga gattgtctcg aatagttcct tcaaagagcc
    14161 aggtatcctg caagaccatt gaaaaggcat catgcacttc tgaacgcgtc atagccttgg
    14221 tatccacacc atcaatgcga atacttctct tatcaatctc atagaatttc atcaaaagat
    14281 tgacaatggt tgtcttacca gccccagtcg gcccaacaat ggcaaccctt tgaccagcat
    14341 gagctgtcac agagaagtca tagtcttgaa cattgacacc gtccaccaga atttctcctg
    14401 ctgacacgtc gtagaaacgt ggaatcagat tgaccagagt tgatttacca gaacctgttg
    14461 acccaataaa ggccactgtt tgaccagttt ctgctttaaa gctaacatgt tcaataactg
    14521 cctccgaatt tgccgcatag cggaaggtca catccttaaa ctcgacctga cctttgaagt
    14581 tttcatcagt cagctgcact tgaacagggt tttggataga agaatgcaaa tctaaaactt
    14641 gattaatccg cttagcagag accatagttc ggggaagaac gatgaagagt gctcccatga
    14701 gaaggaagcc catgacaacc tacatggcat aagacatgaa aataatcatg tcactaaaga
    14761 gaggcagacg cgctatcgga gcagcgtcgt taatcacata ggccccaatc cagtaaatcg
    14821 ctacactcaa accacttgaa atccccatca tgataggatt caaaatagcc ataagacggt
    14881 tgacaaacaa attcaaacgg gtcaattcat catttactgc tgcaaatttt tcattttgat
    14941 aatcctctgc attgtaggca cgaacgacac gaatacctgt taaactctca cgagtgatac
    15001 tgttcagttt atctgtcaac ccctgaatca aggactgttt tggaaaggct agcgtcatca
    15061 aaacggtcgt catcaggacg ttgacaatca ctaccacaag tacggcccag agccagtatt
    15121 ctgaatgacc taaaatcttc ccaatagccc agatagccat aattggacca cgcgttacca
    15181 cttgcaagcc catagtaatc aacatttgaa cttgagtaat gtcattggta gtacgcgtca
    15241 agaggctagg aattgaaaat ttcttaatct ctgtctgcga gtaatccaaa actcggttaa
    15301 aaatatcact tctcagccta ctagtataag aagccgccac tcgggatgca aaaaatccaa
    15361 ctgcaactac ggacaagaag gcaagaaagg acattcccat catcatgctt gccggctgcc
    15421 acaactcatc taaattagtt tcttgactac ctagcaaatc cgtaattttc gagatatagg
    15481 tcggcacttc caactctaga tagaccgaaa agcaagtaaa gagaatggct agtaaaatca
    15541 tcccccattc ttttctacta attcttttgg ctaatttctt tattctctcc tcctattccc
    15601 ttgatatttt gcctgtagtt gaccgagaac cttctcaaaa atcagtaatt catcttcatc
    15661 aatatcttcc atcaactgct tgtctatgcg ttcaaaaaaa gccttaacct gttgcatctg
    15721 agaacgtgct ttgtccgtca gacgaacaaa cttagcccgc ttatcaacag gactcgcctc
    15781 caattccacc aaaccatttt gcactatacg cttaaccaga ttactagcaa cagacttggt
    15841 aatattgagt tcctgatcga tatctttaat caagaccaag tcttggtttt tctcgcgatt
    15901 atccaaaaaa tgcacaacct gaccttgcgg cccacccata aattcaatgc cgcaacgttt
    15961 ggcttccttt tgcaccatca ggtgaatttg atgaccaaaa cgcttaaaga ctaacatcgg
    16021 tttacccata atctccccct tctaaataaa aatagttctc tggagaataa ttaaatttct
    16081 atgagaacta ttttcttgat taaaaaaatc ccaagtgatt ttctcactta ggatcatgtt
    16141 ctataggtta aattaaaacc catctacgtt cgtataaatc ttttggacgt cttcgtcgtc
    16201 ttcaagaacg ctgtaaagtt tttcaaaggt ttcaaggtct tcgcctgaca attccacttc
    16261 tgactgagga atcatttcca attcagtcac ttggaattct tcaataccag actcacggag
    16321 ggcaacgata gccttgtgaa ggtcagttgg cgctgtgtaa actgtgattg taccttcttg
    16381 tgcttctacg tcatccacat ccacatccgc ttcgagcaat tgctcaaaga ctgcgtccgc
    16441 atcttcacct ccaaatacaa taacaccttt gttgtcaaag aggtaagaaa cagaacctga
    16501 agcgcccatg tttccgccgt ttttaccaaa ggctgcacgg acattggctg ctgtacggtt
    16561 aacgttagaa gtcaaagtat ccacaattag catagagcca tttggcccaa aaccttcgta
    16621 acgtccttct gtaaaggttt cgtctgtgtt tcctttggct ttatcaatcg ctttatcgat
    16681 aatgtgtttt ggcacttggg cttgtttagc acggtcgata acgaatttca aagctgagtt
    16741 tgattctgga tctggatcac cttttttagc tgctacatag atttctacac caaattttgc
    16801 atatacttta gagttggctc catctttagc cgttttcttg gctacgatat tggcccattt
    16861 acgtcccatt aggaatctcc ttttttcaca ttttaatctt tcttattata acacaagttt
    16921 ttttgatttt cactagagga aatggatttt attagcaaat caagctagga tagcacttta
    16981 cctgctaaga tggtcttgcc tttctatctt tatcaacaga cactcatcca cattcaaaaa
    17041 acaaactaga ccattatctg caaatagaaa gtttcagcca agtttgacaa agtcagctca
    17101 aattactgtt tgaagtttgt agatataagc gacaaaaaca atcatactgc accttttgtt
    17161 gacagtctac tccagacata tcatagttca agtaaatact ttgaaattca acagttctta
    17221 taggcgctat tgtattctaa gaaatcaata gaagagtttc taagcaaacc tctaatactc
    17281 aataaaaatc aaagagcaaa ctagaaagct agccgcaggt tgctcaaaac actgttttga
    17341 ggttgcggat agggctgaca tggtttgaag agattttcta agagtataat ttacgtgttc
    17401 ctaagatgga gaagttagac tagtacactg gcacttctaa accattgcta gcaattgatt
    17461 tgttcatatt taatttcatt ttttccataa atgggtatta gatataaaca gcaaaatatt
    17521 tccgatacgt gtcattcttg aatttccaat catctaaaac aagtaaagga taatcaatcc
    17581 cctgtatatc aaggaattgg ctaccctttt tactttttta cacatcctgt ttgatagact
    17641 cattttaaca tcacgagcat actccaatgg aaatcgctag gcaagagata aactttcaga
    17701 tatccgcaga gagatcatcg cctctttttg tcgcaagcat tctcctctcc tagtcatttt
    17761 ctaccttatc ctctacctga ggatagagag ttgttcccca aatagaaatc gtccgcttac
    17821 gcactagtgg caaatcggtt ttttcataaa ccgtacgcca ccattcccag gcaagcccgg
    17881 tacactctct aattttgaca gagagattac gaacattccc ttttaaagga atactagtgg
    17941 taaagtgagc cgtcaaatcc tgcccatttc tgtcccaagc cttaggagtc aagacttcct
    18001 taccttgatg atcataggat aattcatccc aagtaatata atattgggca acataggcac
    18061 cactatgatc cagcagtaaa tctccgtttc tgtaagctgt aaccttagtc tcaacatagt
    18121 ctgtactgtt ttgaaaggtc gcaactacat tgtcacgtaa aaaagaagtt gtataggaaa
    18181 tcggcaagcc tggatgatct gctgtaaagc gactgccttc ttgaatcaag tcctctacca
    18241 tatccacctt gcctgttaca actcgggcac ccgaacttgg gtcgccccct aaaataaccg
    18301 ccttcacttc tgtattgtcc aaaatctgct tccactctgt ctgaggagct accttgactc
    18361 cttttatcaa agcttcaaaa gcagcctcta cttcatcact cttactcgtg gtttccaact
    18421 tgagatagac ttggcgccca taagcaacac tcgaaatata gaccaaagga cgctctgcag
    18481 aaattcctct ctgttttaaa tcctctaccg ttacagtatc ttgaaacaca tctcctggat
    18541 ttttaacagc gtctacgctg actgtataat aaatctgctt aaaattaaca atctgaatct
    18601 gcttttcacc tgaatggaca gagttaaaat caatatcaag agaattccct gtcttttcaa
    18661 agtcagaacc aaacttgacc ttgagttgtt ccatgctgtg agccgttatt ttttcatact
    18721 gcattctagc tgggacatta ttgacctgac cataatcttg atgccactta gccaacaaat
    18781 cgtttaccgc tccgcgaaca cttgaattgc tggggtcttc cacttggaga aagctatcgc
    18841 tacttgccaa accaggcaaa tcaatactat aagtcatcgg agcacgatca accgcaagaa
    18901 gagtgggatt attctctaac aaggtctcat ccactacgag aagtgctcca ggatagaggc
    18961 gactgtcgtt ggtagctgtt acagaaatat cacttgtatt tgtcgacaag ctccgcttct
    19021 ttctttcgat aacaacaaac tcatcgggta gctgattacc ctctttgatg aaacgatttt
    19081 caatactttc tccctgatgg gtcaagagtt tctttttatc gtaattcata gctagtataa
    19141 agtcatttac tgctttattt gccatcttct acctcctaat aagttcctgg attgagttgc
    19201 ataaactcag acttgttcag cgaaatcagc cgtggttgga ctaagtgatc caaaatttcc
    19261 tcgtacaatt cttctgagac attgcgtcgc cgtctggcta gataagaagt cggaataacc
    19321 gtattatcca acataaatac cttatctaag tcaatcaagg ttggtcttgt aaaaggatta
    19381 cgagctagat ccggctcttc tatcataaag ttcttgacca aacgtctggt caagagagct
    19441 ggtttgaagg tctgattttt aaccaactct ttgtttttag tcatgctgtt gtcaatacag
    19501 atatacatat gattcttcac agccaaatcg ctactaatag tcggaaaagg caaataaaga
    19561 gctacaacat ctcctctctt aatcaagcaa gagcaccccc ttttctccta atgtaacata
    19621 gacaggattg accaagtctt ctgattgact cagaatttcc aaagtttgag tttggcgcgc
    19681 tgtcaattta gtagcatctt gtctcttcaa tacaaaatgc ttgtcgccaa taaccttgac
    19741 aatataatcc ttctccaaag ctgactggta aatccacatc agatgttgtc tgtcctgaga
    19801 actcaagaga gaaggatttt caagcctccc gatagtctga taaaaatcaa aaacaggagc
    19861 taactcctgc caatctgatt ggctagttgt caaggctaga aaaagggctt tgcgagctga
    19921 tacttcttgg ttagccttga gagttacttt cccctccaag ttttttagaa atcgggaaac
    19981 tccagaaagc aaatttttct ctaactgcga gaaataaaaa cctttcgttc ccagacataa
    20041 gtctttcatg tcgctttctc tagcaaataa gagctcaaac atttgatagt aaaagaaaaa
    20101 tatctggcac tgggtcgcgc tcatcttttc cttatcggct tcttttttta accagagcaa
    20161 gggcgacagg taactggatt gagacatttc ctctacctcc tactcttttt taactggagc
    20221 atctgcacta gctgccactt cttttgactg gatactttcc cactggttaa tctcctctga
    20281 gataagacct tcgcatgtct tgacaaatag ggcaaaagcc ttggtctttc ctgcatattt
    20341 ctccgtttgg cattgataga ggaatttttc tttctccagg agttgcgcag ttttttggta
    20401 agaaatccaa ttttcctttg cattatacaa attgataatc ccctcacaca gcaagccgag
    20461 actggataag gcaaccgaaa tcaaacggta gcgatcacct ggcataggaa tagcacaaaa
    20521 gacagctatg aggaaacctg ccacgatttc tgttattttt aataccttat agcgcctacg
    20581 atgttgaacg cttttcttta aaaaatgagc tatctgtacg tctaatcgct ctgtcaggta
    20641 catttcttct ggcgtcatat tcgtaactcc tttcatttac tttgataacc atagtataac
    20701 atatttgaat atcaaagtat agtaaaaact ggactataac ttattagact tcctgcgaaa
    20761 caaaatatgg tatagtagtt ctatgaatga tgaagcaagt aaacaactaa ctgatgcacg
    20821 atttaagcgt cttgttggtg ttcagcgtac cacttttgaa gagatgttag ctgtattaaa
    20881 aacagcttat caaaaaagtc ggacaagctg gtaaaatctt ggctgacagt aattatcaag
    20941 ggctcatgaa gatatatcct caagcacaaa ctccacgtaa atccagcaaa ctcaagccac
    21001 taacagttga agataaagtc tataaccatg cgctatctaa ggagagaagc aaggttgaga
    21061 acatctttgc caaagtaaaa acgtttaaaa tgttttcaac aacctgtcga aatcatcgta
    21121 aacgcttcgg attacgaatg aatttgagtg ctggtattat caatcatgaa ctaggattct
    21181 agttttgcag gaagtctatt atatatatgc acagacatat gaaatctttt tgatacagcc
    21241 ttctttttac atagagagac agcagttatg atatatttat ccattcacaa catcttctgt
    21301 accaatacta caataattgg tacattttga ttacacaatc gtttcaaaaa atatgatgga
    21361 agactgagta ttttatagta attcccttcc tatcaactag atcaaccagt tgagtgttga
    21421 atgttgaaac accctagcct cagcaaagga ctatgatcag catttcctag ccaataggac
    21481 gctccaaatc acctattcta agtccatcac tagcttggtc agtaagatac agactgcaag
    21541 gcaagactga cgtggttgat gagattttgg aagagtatta caatcataga ttcaccagta
    21601 gacttgaccg cagatttaac tatagtagat tgaaactaga atagtacact tctgcttcta
    21661 aaacattgtt agaaatcgat ttgactgtcc tgatcaattt gtcctgttct cgtttcattt
    21721 tactatacta aaaaaccacc tgaaacaaat caagtgacta gaggataaaa acaaagactg
    21781 ggcaaaaagt tttgaaaagc aaaaaacgca taatatcagg tcttgaaaaa ccttgatact
    21841 atacgtttga ttgtgggaag attgacttca ttttctcctg aaattgaagt tttttctagt
    21901 ttccaggtat agacgaattc aatatagcca tctcgctaca attattttaa ccatcgaaaa
    21961 aatttttcag aatttcaaaa atttcatttt gatccaatga aatgtcatta ttttgaagaa
    22021 tagttgactt cacaggctct aattctatca caaagcggtg catgtctgct tttaccgcac
    22081 tacttgatgt tatagccgat aacttttcat ctcctagcaa ggaagctgtc aaacgggtaa
    22141 ggtcattcaa atgcttttta atggacttac ttaaaccttg agcacctgtg gcagagcgct
    22201 ccctcatatc cagccaagct ttagccttaa aaataattaa tactcaatga aaatcaaaga
    22261 gcaaactagg aagctagttg caggctgctc aaaacactgt tttgaggttg tagatggaag
    22321 ctgacgtggt ttgaagagat tttcgaagag tatagaccac aattactcaa taccgaatac
    22381 ccctgaatgg tttcttttac atgcaccaat atattataat aatcttcatc caataataag
    22441 gctgataaac tagcatcttg gtcaaaatat aagggaattt ctcgaccgtc cttctttaat
    22501 ggatattctg gtaagatact aaatagttca atcatagaag gaaactcaga attagttgtt
    22561 gtaaatcgaa aaagctgcgc tttctcatct ttctgacttc cttgatactc tcccaattct
    22621 aaaaaatgat tcaaggtagt ataaaattcc ttatttttta cttcatcaat gatgaccata
    22681 tcataatctt ttgttgtgcg acttttaaat ccttgcgaat ccaatacgat agaggtagca
    22741 gttcccccaa tcagaacata atagttctga aaatccgcaa acatttcttg aaaaataact
    22801 ttcgtattag ctggcatcat cttctcccag atactgtaat atcatatttt ctagtgcttc
    22861 actctcttcc tctatacgtg ggtcatcatc atcttttaag gtcaaataaa gagaaatcgg
    22921 atctacaaat tgtttatcat gattattttt aaaatcattc caaaactcag atacaaaagg
    22981 acgatatttc catatctcta gcatctttca ttttaaaaca tgctgagaaa gtggcaagga
    23041 taactgattg aattttctct gccatatgac atagctaata ttttcatccg tttcagctaa
    23101 aaaagttgaa tgcgacaaag cataagcacc accatataga aggttagaaa cagattttat
    23161 ctgctttata tcgccatctg gcaataaaat ccgttttttg atgggattaa ataaacatga
    23221 cacggatttt aagaataatt ctttctttga caccgtatat gtgtaaagct tattttgctt
    23281 gtttaaccaa tataaagctt taaaagtcct caaacaccta taaattgttg agtttggaag
    23341 tccagtgact tgtgaaagca aatcaacatc tactactttt tgaccttttg tcaataaaaa
    23401 ggcaatccac gttaattgtt cgctaggtgt taattcctta gggacttcag tatcattcgc
    23461 attgagtact agtcccaatg gagggaagaa gaggtttccc ttaaagtcta caaacggaac
    23521 tctagcttga agtaattgct ttttttcact gtctgataac ttcgaaaaca ccaaaacaac
    23581 atccatattg gctttttcac ccatagtgcg agcctgagta acaaatgaac tcaaactccc
    23641 ccttctcttt tctttaatca ataaaaatga ttccttatga aaagtcattt gagtatactc
    23701 aaaccttttt acaaaactga ttggtaaagt caaagtcagt tcctcaatac tgacatcaac
    23761 ataaaaggat tgaaaaattg acattatctt tttgacattc atgttttttc cttattctat
    23821 catttttatt atattttatc attcggtata ataaaatata agttttttga taaaataacc
    23881 aaaaactact cgctatcccc tctcacatta ccctacatat cgtttgacat gcgactgata
    23941 gttcaggaaa acttcaagga gaacttttct ctcatccact atgcaggact tactatttca
    24001 cttctactcc tataggctca atttgacact tttctttttc gaattgctca tatgcctcct
    24061 gaatagtgag ttcgatttat ccaaatttat ttttgtctat tttgatgaat acttccacga
    24121 agatagtctg aaaatgaatt tgcaccaatt ttccttctct ttttaagcat attattccag
    24181 atatgattgc cctcttgttc agtaataaat tacgctttaa acgcttcaat cagtatatct
    24241 cctgttgtca tatgttctaa agaaaattct tctacatatg atttaacatc tcttaggtta
    24301 ttacttccta atatcccatt atgctttttc gctaaggaaa tagaagccgc ttctccctta
    24361 ccaataatct tgttattatc atgatttctt gttaaatctc tatataatgc gtattcttca
    24421 gttccaatgt ctatgctcac aatctcagct gaacccttag ctaccaactg atctatccta
    24481 gattttaaat ggggaattgt aggtatattg atttcatcat acacctcttg tggaataaca
    24541 attttacccg aatagagctt ttctaaaaga tgttcagtgc caacccataa aaatactgaa
    24601 atacaatctg catcaataaa tacacgacta gtcaaacgac aactcccccc tcttcatcta
    24661 gcccatatac aatatcatat ctgaaagcat ctagtaacag ttcctcatac ttcccttgcg
    24721 aaattctgtt attttctaaa agttgttcag ttgaattaat atattatcct aataccattt
    24781 cctttttact ttctgacaaa ggacgatata aacttgtatc atagcctaat cttgaagctg
    24841 tctctataac actaatatcc atatttttaa tttcttctgc atcaaggtat ccatcattcc
    24901 tcaatctata taacatagct ttatgactga taccataaaa ctgacccaat tttataatat
    24961 cttctacttc aagatgagtt ctattggcat tttctctgat ttcctcaacc atcctataca
    25021 gtgaagatgg gaaaattaaa aaataagaag caagctgatc cgcttttctt tcagtttcat
    25081 ctccttcacc aatcaagata agactgactg aactcttctt cacctcatca taataaagat
    25141 gatacagttc atgtgctaaa gaaaatcttt accttcctaa tgacatgtct gaattgactg
    25201 caatgagact gaactgagtt cctttataac agactccgct aatattcttt ccgagtccat
    25261 aaaataccag cgtcaaattt tctatctttt gtaccaattt aaaaatatct atcggcgctt
    25321 caccatcagc tcccaacttt tttctaagat ttgaagcttt attacttaaa tccattcgtg
    25381 atattccttt cacctttttc cattttggca atcatgcttt gattcaaaga caaatataaa
    25441 gacaaatatt cagcaatctt atcttgagta agatttgaag atattctaag ttcttttatt
    25501 ctttttccaa catcacatac atttatcaca tacatttatc atattcatac acctctcata
    25561 aaaagaatag cacacttttg tcataatttt ttaaataaaa aaattatgac aaaacaagga
    25621 agcaatttat tgatgctgct taaaaatcta aaattgatga gttcctatca aaaatcgtat
    25681 cttcaacctc aaaacagtac ttaaagctat ccgactcggt ttacattgtc aaatttagat
    25741 tttatttgag cataactttc tagtttgctt tctgattttt gtttaatata gtagcaaaca
    25801 ttgaaggaaa tatctccaca agaaaacgca tactattaag ctttttcaag acctaataat
    25861 atgcgctgtt ctgatttgaa agacattcca ttattatttt actgtaatca agccatctgg
    25921 ctctactgtg aattctggcc tgtctgccag tgttccgtct ggtttgaggt agtaccagcc
    25981 tgttccgtcc gctgactgga taaaggcatt tgataccatg gcgccttctt tagcgtctaa
    26041 gtagtaccaa gtgtccttgt acttgaccca gcctgtcttc atggcacctt cttcgttgaa
    26101 atagtaccac ttatcagcga ttttcttcca gcctgtagcc atttcgcctg agttgtcgaa
    26161 ccagtaccag ttgccgtctg tgtgcttcct ccagcggtct gcaagcatat agcctgaact
    26221 gtcaaagtag taccaagtgc cattgatttt ctcaaacttg tcttttggat aagagccgtc
    26281 tgaatgtacg taccagtagc cagtgtcatt cttctgccag cctgtttcaa tcgtcaagcc
    26341 gttctcaata tcatgcttaa actgctcacg gctaatgccc catttagcaa gatatggata
    26401 agggtcaacg tggtctgagt ggttgtttgg ttggttattc gtgcaatact cgtgcgtttt
    26461 aattccagct aaactccctg tatcaagcgt tttcggcaaa cctgcttcat ctgctagatt
    26521 gcgtaagagt tcgatataaa ggcggtagtc cgtcatgaac tcttctttgg ttgaatggct
    26581 ttcaatcagt tcaaccgctg cataggtctc agcattccaa ccgcccccaa cgtcccaggc
    26641 accattatca acaggtccta cctgcatgat gcaaccgttc ccaacaatgt gcgagaaaaa
    26701 acctaattct gggtctttcc gccagtgata atccgcttca ttctgtacgg ttgaatgcgg
    26761 attcccagtt gagtgtgcgt gtacttgcct atatggttgc acgccgactt gaggcaaatc
    26821 tgttcttaat ttactcacat taatttccat attctactcc ttatcaatta aaacaactca
    26881 ttttttacaa tccagaacca gaaactcctt tatttctacc ttacaaagaa gacaatctta
    26941 gtcacgatta ggcttgtaga tagaacttca aaacgcacta ttttgacact gtaaatagga
    27001 ctgacaaggt ctgcattcta tctacaataa caccccagac taaaaagctt ttcaaaagta
    27061 tatttttaca gtctctatat gtccttttca taaatactat actttattat atcatataaa
    27121 agaagtcaaa agtctgttaa actattttca acaccaaact aaagacgaga acacaagttt
    27181 tttcgatttt cactagagga aatggatttt attcagtaaa tccaactagg attgcacttt
    27241 ggttgccaag attgccttgc cttcttttat caagggatga cggaataatg agaagtacag
    27301 ttgaactgtc atggcaaccc agataagagg ttcacaaagg ataacaccct tatatcctgc
    27361 ccaaggaata atcaaaacca caaaaacgat ttttccgatt agttcaataa agctagaaac
    27421 tagaggaagg atcttttgcc ccaagccctg caagcaattg cgataaatca acaagaggct
    27481 caaaatggga taaaaggttg aactgatttg cagatagaga cttccatttt ctatcaagta
    27541 accatctgtc gaactagcca agaaggaaac caaagctgga ctggcaaaaa agaggaaaat
    27601 acaaacaaaa actgcccagg atatacttaa acgactgccg attcgaagac cttgaacaat
    27661 acggtcaggt cgcttagctc ctagattctg agaagcaaag gtcgtcattg atgcagaaat
    27721 agcggtcata ggaagaaggg caaaggtcat aatgcgtcga gctgccgtct gggcactaat
    27781 aatcactgca ccaaatgtat taacagaaaa ctgtaaaatc acactgccga tagatacaat
    27841 tgaactcatc aagcccatag ccaaaccttg ctccaagaga tccgcgtaca agcttttgtc
    27901 ccatttgaaa tgtttaaact gtggcaagag ttctggcaca cttttacgaa tataataaaa
    27961 gcagagaacc gctgataaac cttgcgaaat aatggtagca agtcctgcgg attgaactcc
    28021 cagatgcaat tgcgtaataa aatagagatc cagaaccaca ttaaccaagg cagagaaaat
    28081 cagaaatccc agggctgcta gactgtcacc aatagaccgc aacaagcctg caaaaagatt
    28141 ataagcaaag ctgacaccta cacaggtcac aatcatagaa atatattgat aagattgagg
    28201 aagaatttct gcaggagtat ctaagtattg caagagagga tacaagccaa gaaagcccag
    28261 caacataact agaatgctca aaagagcacc taaaatccag gtggctgcta ctgcttcctt
    28321 gattttagtg aaattccgag ccccataata acgagcaatg acaatcccca tgccattgcc
    28381 aacaccaagt gtaaagccta caatcaggtc aaaaatcgct gtcgtcgctc ctactgcagc
    28441 caaggattct tgaccaagaa atcgtccaac aatcaagaca tcagcagtgt tatagagctg
    28501 ttgaaaaata tttgatagca agattggaaa ggtgaagctt aagagcgagg gaagaatcgg
    28561 accatgtatc aggtccactg ttcgtttttt attcataaag ctattatatc agctttccag
    28621 aggagcgaca agaaacagca aacttatata tagcggaatg aaataaggac agtcaaatcg
    28681 atttttaaca atgttttaga agtagatgtg tactattcta gtttcgatct attatagttg
    28741 gttgagtttg gaatagtacg ctgtagctgc taaaacattt ctagaaatta atttgacttt
    28801 cctaataaag ttgttcatat cttatttcaa gctactatat ataatatata atctaaaaac
    28861 ttgaatcaaa aatcgaaaaa gtagcggatt tctccactgc tttaacagct tattcttcaa
    28921 tttcgatttc aagttcatcg cctaagtcaa gcggaacttc ttcattcact gcttcttctt
    28981 tctttggctc atcttttttg ttttcagtat cttgttctga aacttcttct ccatcaatca
    29041 agccaaattt agaacggact tgcttatcaa tttcatcaaa gatttctggg tgctctgcca
    29101 agtatttctt agcattctca gaaccttgcc caattttttc atctttgtaa gaataccaag
    29161 cccctgcttt tttgataata tccaaatcgc ttgcaatctt caaaagctca ccagtcttag
    29221 aaattccttc tccgtacata atttcaacta cggcttcctt aaacggtgga gctaccttat
    29281 tttttacaac cttaatctta gtttctttac cgacattggt ttctttttga tcaccagttc
    29341 ccttaatttg tgtattacca cgaacatcca agcggactga agcatagaat ttcaaagcac
    29401 gtccgcccgg tgttgtttct ggatttccaa acatcactcc aactttttca cgcaattggt
    29461 tgataaaaat ggcaattgtt ttggttttat tgatagaggc gccaagttta cgcatggcct
    29521 ggctcatcat acgagcctgc aaaccaacat ggctatctcc gatatctcca tcaatttccg
    29581 cacgaggaac aagggcagca actgagtcga ctacgacaag atcaactgca cctgagtcaa
    29641 tcaattttcc cgcaatctca agaccttgct ctcctgagtc tggttgagac aagagcaatt
    29701 cgtcaatatt gacaccaagg gccgcagcat aagctggatc aagggcatgt tccgcatcga
    29761 taaaggcagc aatcccacct tctttttgcg cttgtgcaac tgcatgaagg gcaaccgttg
    29821 tcttaccaga tgactctggg ccatagattt cgatgatacg tcccttagga taaccacctg
    29881 agccaagggc aatgtcaaga gctaaagaac ctgagctcat cacttgcacc ttttgctccg
    29941 cacgttcacc caaacgcatg attgatcctt taccaaagtc tttctcaatc aatttaagag
    30001 cgtcattcaa ggccttttca cgttctgccc caaatttttt tgaaatttct tctaattttt
    30061 ttggtttttt cgccattcta ttctcctaca ttctaatgat cctcagacct atctactatt
    30121 atatcaaaag ttagtcactt aataaagcct tgcgaactag gttaaaggca tgcataaccg
    30181 caatgtgacg tacatctgct cggcttctgc ctccaatatt aaccttgata acctcagttc
    30241 cttgatcttg cgccaagcct atgaagactg tcccaactgg gtgtccttct aggctatctg
    30301 gtcctgccac tccagtcaaa ctaattccaa aatcagactg ggtcttgctt cgtgcctgct
    30361 cagccatctt ctgagctgta aattcagaca ccacaccatg ttcttccaaa ttcttggcag
    30421 gaatatccaa catccttgat ttttcctcca agctataggt cacaaaacca ccctcaaata
    30481 tacttgaaac tccagaaaaa ttcgccacgg tagcttggaa aagacctgcc gtcaaactct
    30541 ctgcagccgc gatggttttc ccttgccttt tcagttcttc taccacaatg ctggctaaac
    30601 tagtttcttc cccataacca tagcaaaagt ctcgtaaaga aattccttcg aaagtctggc
    30661 agtccaagat ttgattttcc aagatatcca gcgcttgatt cgcctcttct tgactgctag
    30721 cctttgttga cagacgtaga gtgacttctc ctgtcttggc ataaggggcc aaggtaggat
    30781 cgatctgatt atcaattaaa tcagccaaaa tcgtaaccaa ctggctctcg ccaatcccaa
    30841 agaaacgaag aactcgggaa tacagcttgc tccctgtcat caacttgggt agaagttggt
    30901 ttaagaccat gggtttcaat tcacttggcg gacctggaag gacgacatag gtcactccgt
    30961 ctacttctaa ttttcctcca acagccagtc ctgtttcgtt tggcagtgga atcgctcctt
    31021 ctacaatttg agcttgtctt tcgttattcg gtgttcgggc atagtctggt cgcagggcaa
    31081 aaaagatatc caacttctcc tgagcctgag gatcaaagac taatgctttc cctaaaaatt
    31141 tagctagggt ttgtttggtt aggtcgtcct cagttggccc caaaccgcct gtcaaaatca
    31201 ccagactgct acgttgactg gcaatctcaa gcaaagacaa gagacgaact tcattgtctc
    31261 ctacagccgt ctgaaaatat acatctaccc caatctcagc tagtttttcc gacaaaaact
    31321 gggcattggt gttgacaatc tgtcctgtca aaatctctgt tccaacagca atgatttctg
    31381 ctttcatgtt tcctcctacc tatctattcg tatttttttg aaaaaatcgc aggaattttc
    31441 ctacgattga tttttttatt tgtatcaaaa gttaattatc ttcatcacca acaggtgctc
    31501 tgccaaataa atcttcaaat aaaaccgcat tggtttcaag ctgagtaact tcttcttgtc
    31561 ccaaagaacg tcggagtata ttttgcattt ccaacatatg tgctctcgaa acaatctggt
    31621 aagaaacacc ttgaagtatc tctccttcac cctgcaactg ctgagtttca atggttttaa
    31681 atgaatcttt atagcctagc aagttaggga tactttttgc agacaaatca atattggtct
    31741 gcatattgtc actcaaagct tttagaatct cttgataatg accaatgcta tttaaactga
    31801 gagctttttc catgactttt tgaataactt cacgttgacg tttttgacga ccataatccc
    31861 cctcaggatc ttggtaacgc attcgtgcat agactagggc ttcttctccc ccaatatgtt
    31921 gctccccaac accgatagaa atggtattaa attcttcttg gtcactgata gaaattggga
    31981 aacctaggat attattgact gtaatacctc ctactgcatc cactaatttt tgcaaccctc
    32041 tcatattgac catcacatag cgatcaatat ggatattcat cattttttga atggtttcta
    32101 tagcaagctc tgctccacca tctgcatatg ctgagttcag tttcgcttca tgagcctgac
    32161 cattccctga ttcaatgcgc gtcagaatat cccgctctaa actcatcatt gttgtttttt
    32221 tcgttttagg attcactgtc atcaagatca tgctatcact tctaccgacc caagtttcag
    32281 ttcgttcaac atttccggtg tccactccca ttaacagaat ggttagaggt tcagtcgctt
    32341 caataacctt ggtttcttca ccgatttttt tataggtttt agctaaggtt tctgtccctt
    32401 gttgataaat agtataagca aaaacaccta ctcctactac agttacagaa agtaaagcta
    32461 gcaccattcc aataattttt ttaaccatat ttctactaac ctatcagttt acccatcaag
    32521 taaacatcga taaatttccc ttcttctata tatgccccac gctcttggct accttcaatg
    32581 acaaagccat gcttttgata aagatggact gctgcttgat tacgagtttg gacagtcagt
    32641 tggagacgac gcagaatgcc acttgcttgt gcccactcta tcgcttcttc tagcaacaaa
    32701 cttcccaagc cattattcca atatcttttt ccaatcacaa tgaagagatc tccaatatga
    32761 cggactctct tacgctgatc agctgtaata tttacaatac cagcaatttt gccatttaag
    32821 aatgcaagta aggttatctg attgtccgaa ctagcttgct tgttgaggaa tatttccatc
    32881 tcctcactag tcaagagaat accatctccg tctaggctgg taaagtctgt ctccaaactc
    32941 acacgattta aaaaggccac taattcagct gcatctttgg gctctgcttc cctaatgagc
    33001 aattcatact ccatattgaa gctcctctaa caatttctca gcacgcaaac cctttgcctg
    33061 aaaatttaaa cggcgtccat ctgcttcttt tagaatttcc aattctaaat aagcatctgg
    33121 caaggcatct cctaagagat ttccccactc aataacagtc acgccgccac caaagataaa
    33181 ctcatccaag tcgatagaat cagcatctcc ttcaatacga taaacatcta ggtgataaag
    33241 tggaagtcga ccttcatact ctctcacgat agtataggtg ggacttttaa tcatttgaga
    33301 aatctgtaat ccttttgcaa gtcctttagt aaaggtcgtt ttacctgcac ccagttctcc
    33361 agttaagatt aaaacatcat tctttgctaa tagatggccc aaacgctccc ctaaggcttg
    33421 caactcttct tcattttttg tgtacatact cttattatac caaaaacttt tcttttgtgt
    33481 ctattttcct actaaactta tcatcataac atccataaaa aacaggcttt ctctaaaaga
    33541 aaatgagcgt aacaatgacc aatacaagat ctcggaaaat atgaccataa aaggaaactt
    33601 ccttcttaac cgaatttggg acaagatagg ctgcaaaaaa caagcccagt ccaatataaa
    33661 tcagaagtga gacaatggtc attggatttc ttaagaaaag aagtgttgct aaaatagtca
    33721 ccaacactgt cttttttctg tccagcatag caagaaaatc gcgcacgtat tttttcaagg
    33781 gtaaaaaaat cagcaaatct agcccaaata ggaaaaagaa ggatggcaat aaaaagtcaa
    33841 ctaattcttg ctgcagcgta tttttgatga acaagttatc tgacaaaaca agaacagctc
    33901 ctaacaaatt aattaagagt aacatactgt aaaaaagctt caccgacttc ttactggcta
    33961 ggacactatg gacttcttgc ttacgggtat aaagataatt tactccagca cagattcctg
    34021 aaacgaaaac catgcttccg atgaaaaaag ctgtactttg tttaaaggac aagatgcatt
    34081 ccttccatag gaaacagcta ctcaaactga tttgaattaa agctaacaaa aataagattc
    34141 tcattgattt catcttctct ctcccttcct accaatcatt atactaggag aaaagagaga
    34201 actgtttcta atcttctcaa atgtctcttt aagacgctaa acaaacacta gagactaata
    34261 ctcaatgaaa atcaaagatc aaactaggta gctagccaca ggttgctcaa aacagtgttt
    34321 tgagattgca gatagagctg acgtgatttg aagagatttt cgaagaatat aaatttgaaa
    34381 tcatgaaaat ccgtcaaacg ggtgattgtt ttgtctcgca cctcacggag cgagacggac
    34441 tcagagtcac ataattataa ggctgatagt attaatctaa ctatcagcct tacaggttat
    34501 ttaacgtttc agaaaaacta taatgtcaag attaactaaa cagtatctag ttccttcaaa
    34561 taattttcta tcttcatcaa cattaaagga ttgttataaa tcttacataa ctctcttgct
    34621 tctatataat aatttttgac ttgttctctg tctagaaatt tggctccagc atttcctaca
    34681 agaataagta gaggagccaa ttggtagctt gtctgtcttt gtttacagag ttcaatcgtt
    34741 tcaagagctt cttggatggc ttcattatat ttttcctttg atactaggta gtgagcgtag
    34801 ttgtaacgaa ctctgatgta gccaaataaa aactcttgat ggtccaaatt ttttgtctga
    34861 tacaactcta ttaaatgaga gtagtttgcc tcatattctt gttcacgacc cactaaggaa
    34921 tagaaattag atagagtatt caacgccttt aaataaatca gagtatttga agagactttt
    34981 aataatatat tttccaatga cgaaattgcc tcacacttac tgtcatattg atagaagtca
    35041 attatagatt taatccattc aaggtaagtt cggtcttcta atgttagaaa agtgcttcgt
    35101 tctacctcta ttttataaag atattctaaa tcgtcataat ttctgtcatc taataggcga
    35161 gcagatagat gtttgaaatt agagaggtta gacttaactt cgatttgttc attgaaaaag
    35221 taatccaaag ggacttcaag tcgttgagag agtttgaata acaagtctgc ggagggaata
    35281 aaatgacctc tttcaatttt actaatctgg ctttgttcac aaattccttc tgcaagagtt
    35341 tgttgggaga gtctcaactc ttttcttttc aatctgaatt tctctgcgag tgtattcatt
    35401 aaagataata aaccttccta tttgcttaat ttcattataa agtttttagt tcaaaatagc
    35461 aagttaaagg aataaataat tctttatggt aataaacaaa aaaaaaagtt aaaaattaca
    35521 taaaaatact tgactaaata aaatatatct gttagaataa aaacaaggaa aaagaaaggg
    35581 gtttcattgc atgagaaaaa aacgtggaat taaaaaatta gttacatttg cattgctagg
    35641 tgtttttatg tttagtaata caattcctta ccaacagttt attcagaaga ataaacaatt
    35701 ggagattcga gtgcaatcgc aaaagaagtc caatggtctt gatgttggga aggcggatta
    35761 aaacccgata ttttgcacga gaatgagaga attataattt atctgaaaaa acgaaaaata
    35821 tagagcaact tatttaactt tttataagga ggagttatta cttatgacca actttaattc
    35881 aaacgaaaaa ttttgtggaa aaagtttaaa atcattgtct gctgatgaaa tgagtttaat
    35941 ttatggtgca tctgatggtg cagagccacg ttggacgcct actcctatta ttttgaaatc
    36001 agctgcagct agctcgaaag tatgcattag tgcagctgtt tctggtattg gggggctagt
    36061 tagctacaat aatgattgtt tggggtaaat taaaatgaaa aatgattttg taatcggaaa
    36121 gagtttgaaa gaattatctc ttgaagaaat gcaattggtt tatggtggca cagatggtgc
    36181 tgaccctaga tcaacaatta tatgttctgc tacattaagt tttattgcat catatttggg
    36241 gtcagctcag actcgttgtg gcaaagacaa caagaaaaaa taaaatattc aattttaaaa
    36301 ataaaagttg ctctttattt tcctctctcg taactaataa ttttgagaga ggtttttttt
    36361 taaaacaata gtaagtcgta taggtttgag gtaagtaaat gaaatataaa attaaaaatg
    36421 tgcataaaac attgtttatt aaggaaagat atcaaatatt atctgaacga aatgataatt
    36481 ccttaaataa cttttcatta aataattggc gttctacaat gtcaattatt tctgaaaaaa
    36541 cttttgaaga aatgttgaaa ttaaataatt acaataaaaa aatattttct aacactgtga
    36601 actatgatta taccgaggaa cagataagac tatattcaga atatgccaaa aattcggaat
    36661 ggtataaatt tgcggagggt tcatttgaaa tatttagaaa acatccccaa agaattaatt
    36721 ttaagaaaga tttttctaga attttggaac cctttattat taatttgctt aaattaatca
    36781 ataattatct agagaataaa gaatacgagt ggattgacaa gaatggaaat attttttcct
    36841 ctctagtatt ttatttagaa gatttaatct atccttggat tgttaaacct ttggttttag
    36901 agataaattc attgcgtgaa aaaggtttac ttgaagggga atcggagcag caacggtaca
    36961 aatattttat aacattgttt gacaaggaag agaatatatt aaatttttat aacaaatatc
    37021 ccgttttact gaggcaaata tcggagtctt gtcttcggtt ctatacttat tttatagaaa
    37081 ttttatcaaa tttagaaaat gattttagtg tgctagaaga agaattaggg ctaaggggga
    37141 aattaaatga tataaaattt ggaaagggtg atacacacag ccaaggaaaa actgttttga
    37201 tactcttctt tgatgacgcg aaaattgttt acaagcctaa aaatttaata atcaataact
    37261 cactaaatac tattgctgag tatatccgaa aggttgatga aaaaattagg ataagaatac
    37321 ctcgaactat tgcttattcg gatcacagct atgaagaatt tattgattat ctacctctag
    37381 agcaaaagaa aaatttacct gaatattatt ataattttgg tgtgctttta gcatttatat
    37441 atttatttaa tgggagtgat atacattttg aaaatttaat ttcctatgga gatatgcctg
    37501 taataataga ctttgaaaca atgttacagc aacctctatt tgatgataaa actggtcaga
    37561 gtttgctgga taccctgttt cacagggtga ctcgaacttt gcttcttcca acagagggag
    37621 taaaaaggga ggatggtctt gatgttgaga tgagtgctct tacaggaaat tttaagaagg
    37681 atgcttttaa tggtcaagtt ttaattaatt taaatactga taaggtaaag tttgatattg
    37741 ggaaaattga ttttgaaggt gggaaaaacc tgcctgttcg ggatggtgat atagaatttg
    37801 ataagtatat aaaagatttc aaaaaaggtt ttagggattt ttatctgata tttgaagagt
    37861 taaataaaac agaagaattt aaaatgctat taaaagcaaa cttgtatggt ttaaagacaa
    37921 gggtactttt tagagacaca aatagctatg cttcagtact atctttttta tatcatcctg
    37981 atttttatga agaaatgtta gatagagaaa aagcattgga aaatctctgg agcaataagt
    38041 tttctaatca aggtattgta gcaagcgaat gtgaacaaat gaggttatta gatattccga
    38101 ttttttatac agatacaaat atcaatgaaa tctacgatga ttttggaaat cattttattt
    38161 ccctacatca attttctgga tatgactatt ttatgaaata tttacctaat aataatttgg
    38221 aaaatttaga aaagcaactt gatatcattg aaatttattt tccaagcttt gatcagcgaa
    38281 aaa
//
LOCUS       DAYYYC010000016        38175 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.016, whole genome shotgun sequence.
ACCESSION   DAYYYC010000016 DAYYYC010000000
VERSION     DAYYYC010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38175
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.016"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            579..959
                     /gene="dhaM"
                     /locus_tag="ACHBV5_000868"
     CDS             579..959
                     /gene="dhaM"
                     /locus_tag="ACHBV5_000868"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFM9966695.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            1419..2132
                     /locus_tag="ACHBV5_000869"
     CDS             1419..2132
                     /locus_tag="ACHBV5_000869"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFM9966696.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2146..2793
                     /locus_tag="ACHBV5_000870"
     CDS             2146..2793
                     /locus_tag="ACHBV5_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966697.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRLFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNIFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            2931..3584
                     /locus_tag="ACHBV5_000871"
     CDS             2931..3584
                     /locus_tag="ACHBV5_000871"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFM9966698.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3594..4058
                     /locus_tag="ACHBV5_000872"
     CDS             3594..4058
                     /locus_tag="ACHBV5_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFM9966699.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4071..5339
                     /locus_tag="ACHBV5_000873"
     CDS             4071..5339
                     /locus_tag="ACHBV5_000873"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFM9966700.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIASEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5353..5613
                     /locus_tag="ACHBV5_000874"
     CDS             5353..5613
                     /locus_tag="ACHBV5_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966701.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5624..6985
                     /gene="pdrM"
                     /locus_tag="ACHBV5_000875"
     CDS             5624..6985
                     /gene="pdrM"
                     /locus_tag="ACHBV5_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HFM9966702.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7139..8107
                     /locus_tag="ACHBV5_000876"
     CDS             7139..8107
                     /locus_tag="ACHBV5_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HFM9966703.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGSVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8123..9115
                     /locus_tag="ACHBV5_000877"
     CDS             8123..9115
                     /locus_tag="ACHBV5_000877"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFM9966704.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEEISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCSGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            9333..10376
                     /locus_tag="ACHBV5_000878"
     CDS             9333..10376
                     /locus_tag="ACHBV5_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HFM9966705.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10422..12125
                     /gene="lpdA"
                     /locus_tag="ACHBV5_000879"
     CDS             10422..12125
                     /gene="lpdA"
                     /locus_tag="ACHBV5_000879"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFM9966706.1"
                     /translation="MALEIIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELEAEEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTS
                     NDDGKSDDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHSAEIIENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            12189..13178
                     /locus_tag="ACHBV5_000880"
     CDS             12189..13178
                     /locus_tag="ACHBV5_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFM9966707.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEAVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13251..14321)
                     /gene="xerS"
                     /locus_tag="ACHBV5_000881"
     CDS             complement(13251..14321)
                     /gene="xerS"
                     /locus_tag="ACHBV5_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFM9966708.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(14829..16379)
                     /locus_tag="ACHBV5_000882"
     CDS             complement(14829..16379)
                     /locus_tag="ACHBV5_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HFM9966709.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16395..17174)
                     /locus_tag="ACHBV5_000883"
     CDS             complement(16395..17174)
                     /locus_tag="ACHBV5_000883"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFM9966710.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKEN"
     gene            complement(17161..18012)
                     /gene="ylqF"
                     /locus_tag="ACHBV5_000884"
     CDS             complement(17161..18012)
                     /gene="ylqF"
                     /locus_tag="ACHBV5_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFM9966711.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWCQYFESQEIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(18258..23507)
                     /gene="zmpD"
                     /locus_tag="ACHBV5_000885"
     CDS             complement(18258..23507)
                     /gene="zmpD"
                     /locus_tag="ACHBV5_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease D"
                     /protein_id="HFM9966712.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVIGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVQPALPEAVVTDKGEPEVQPTLPEAVVTDKG
                     EPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEP
                     ISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVKEVGEDGERQIVT
                     SYEELHGKKISEPVETVTILKEMKPKILVKGTKENPKEKTVPVLTLTKVTEDAMNRSA
                     NLNYELDNKDNAEISSIIAEIKDGDTVVKKVDLSKEKLTDAVQNLDLFKDYKIATTMI
                     YDRGQGSETSKLDEKTLRLELKKVEIKNISSTNLVKVNDDGTEIPSDFMSEKPSDEDV
                     KKMYLKITSRDNKVTRLAVDKIELVTEKEKELYKITASAQDLIQHVDPSKTRNEYIHY
                     IEKPVPKVNNVYYNFNELVRDMQEHPNDEFKLGADLNATNVSAFGKSYVTKDFKGKLL
                     SDGDNHYTIHNLSRPLFGNVIGGTIKNINLGNVDINMPWANQVAAVANIIKGGTTIEN
                     VKVKGNIVGKDWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVE
                     RAYVNANLIGKKAKAAGIAYWTQNEGNNNTVRQEGAIKKSIAKGTIQVTEAIESGGVV
                     GSMKHHGSVEDSVSMMKVPNGEIFYGSSDIDYDDGYWTGDNVRRNYVVIGVSDGHSSY
                     QRSKDKNRIRPISEEEAKSKIEATGITADKYEINEPVVNRLNRLTRREDEYKSTQDYK
                     VDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDI
                     DHVMIHYADKTKEIKAVHQKESKVAQVREYSIDGLDDIVYTPNMVDKNRDQLIKDIKD
                     RLATVELISPEVRALMDKRDTSRDPNANSDERKNGYIRDLYFEESFSETKANLDKLVK
                     SLIENADHQLNSDEAAMKALVKKVDENKAKIVMALTYLNRYYDIKYGDMTIKNLMMFK
                     PDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFT
                     NDTDLNDWFIHAAKNVYIVEPKTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAH
                     MFLISTYNTMAYSSFEKYGKYTEAEREAFKDKIKEVAHAQQTYLDFWSRLALPSVRDQ
                     LLKSQNRVPTPVWDNQNYHNVEGVNRMGYDKNNKPIAPIRELYGPTWRYHTTNWYMGA
                     MASIFQDPNNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAY
                     AQGMLQTPDKSGNGEYGALGLNMAYHRENDGDQWYNYDPDKLKTREDIDRYMRNYNDA
                     LMMLDHLEADAVIPKLHGNISRWFKKMDRQYRKNGELHQFDKVRELTEDEKKKIVINN
                     IDDLVNNNLMTKHGAPSDRTYNPEDFDSAYVNINIMTGIYGGNTSQGAPGAASFKHNT
                     FRMWGYFGYENGFISYASSKYQGEADKTNKKLLGDDFIIKKVSKDKFNNLEEWKKQYF
                     KDVKSKAEKGFTAIEIDGRQITNYAQLKTLFAEAVQKDIDGMSDPKIKDHFKNTVDLK
                     SKVFKALLKNTDGFFNKLFKEDI"
     gene            complement(23551..29175)
                     /locus_tag="ACHBV5_000886"
     CDS             complement(23551..29175)
                     /locus_tag="ACHBV5_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HFM9966713.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIEIKIDFQEEI
                     QENPDLVEGIVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSKAVITDKG
                     ETEVQPESPDTVVSDKGEPAVQPELPEAVVTDKGETEVQPESPDTVVSDKGEPKQVAP
                     LPEYTGPQASAIVEPEQVAPLPEYTGVQAGSIVEPEKVEAPKEYTGKIEQPSAEDTKP
                     ENGASSTNGESERPKDKIKEEKQVDKKLELRNVSNVELYTVENNKYRHITAVDGALDS
                     SLKYFMKVKSENFKDIMLPVTKIESTTKNNKEVYKIVAHAENLIQHENNVISNDYTYY
                     LPKTQQSETGVYTSFKNLVDAMNSDPNGTFHLGATMDAREVELPDDQESYVKNEFYGK
                     LIGKNNGKYYAIYNLKKPLFKTLNTATIQNLSIKEANVSSKEDAATISKEAKYNTLID
                     NVHSDGIIAGERGIGGLVSKVDNSRISNSSFTGRITNTYDTTAGYEIGGLVGKLSGSL
                     ASIEKSIASIDIASNAKSGDQIVGGIAGVVEKSATIKYSYVEGNVNNVRHFGKVGGVA
                     GNLWDRDSQDVSKSGKLSYVLSDVNVTNGNAIAGYNFNGIKTIETYSNKNNKVVNVVQ
                     EDDEVVTKDSDVQRGTVLDADKVKEKKVELVSKHSTKVEDFDFTSRYNTNYNEVTGYQ
                     QSREQVYKNIEKLLPFYNRETIVKYGNLVEDNSDLFTKKLLSVVPMKNNEVITDINKN
                     KQEINKLLLHFEGNKSRVLNIAYKNDFSKVAEYDIANTKLMYTPNTMLHDYNNIVKTI
                     LNDLKSVQYSSADVRKVLDISGNIKLTELYLGEQFEKTKANIEDSLSKLLTADAAIVE
                     NNNKVIDNYVIEKIKNNKEALLLGLTYLERWYNFNYGETNAKDLIMYHLDFFGKSNSS
                     ALDNVIELGKSGFNNLLAKNNVITYNVLLAKNYGTESLFKALEGYRKVFLPTISNNEW
                     FKKQTKAYIVEEKSTIEEGREKQGKEGTKYSIGVYDRLTNPSWKYQSMVLPLLTLPEE
                     KTVFMIANISTIGFGAYDRYRSSEYPKGEKLNKFVEDNAKEAAKRFRDHYDYWYKILD
                     NDNKEKLYRSILVYDAFKFGTDKDKDKVTHQATFETDHPAIKYFFGPAGNNVVHNGHG
                     AYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRSGLGPEFYAKGLLQ
                     APDHPYDPTITINSVLKYEDSENSTRLQVADPTQRFNSAEDLHNYMHNMFDVIYMLEY
                     LEGKAVANLETNQKYELLRKIENKFDLDQDGNNVYATNVVRRLTMDEVNKLNSFDSLI
                     ENDIITSRGYKDQEYKRNGYYTIDLFSPIYSALSGEKGTPGDLMGRRIAFELLAAKGY
                     KEGMVPYISNQYEKDAKAAGSKINSYGKEVGLVTDELVLEKVFNGQYKTWTQFKKDMY
                     KEREKQFSKLNRVNFINPNNPLSRQRNVSVTDIGVLERMIVEAVRDDAQDDVAKFYPE
                     TNSRVLKLKKAIYKAYLDQTNDFRSSIFENKK"
     gene            complement(29384..30562)
                     /locus_tag="ACHBV5_000887"
     CDS             complement(29384..30562)
                     /locus_tag="ACHBV5_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966714.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSIC
                     VCGNVIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDYRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(30777..34427)
                     /gene="addA"
                     /locus_tag="ACHBV5_000888"
     CDS             complement(30777..34427)
                     /gene="addA"
                     /locus_tag="ACHBV5_000888"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFM9966715.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGCQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFCFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     HVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(34424..37699)
                     /gene="rexB"
                     /locus_tag="ACHBV5_000889"
     CDS             complement(34424..37699)
                     /gene="rexB"
                     /locus_tag="ACHBV5_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HFM9966716.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGAEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYIDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERKNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGELYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            complement(37899..38054)
                     /locus_tag="ACHBV5_000890"
                     /pseudo
     CDS             complement(37899..38054)
                     /locus_tag="ACHBV5_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT        11054 a         7445 c         7290 g        12386 t
ORIGIN      
        1 gcggaggcct tgctagaaaa agtaacagat tctagtatta gacaaaatgc tgtggagaca
       61 ttgactggtc taaaaagtag tcttcttctc ggaacgaaag ataataacac tatttcagca
      121 gaagtagata gtctcttggc tttattaaag gagagtaagt aaaggtagca gcattttcta
      181 actcctaaaa acaggatagg agaacgggaa aacgaaaaat gagagcagaa tgtgagttct
      241 agttctcatt tttttcatga aaatgtgcaa aatatagtag attgaaacta gaatagtata
      301 cctctacttc taaaacattg ttagaaatcg atttgactgt cctgttctta ttttactata
      361 tcttaacaga tagtgtaaat aaagataaac tatttactgg ctaattaatc agttaaacac
      421 tagttaagga gtaatgatga aaaaaagaac aatactatta ttgatgacca gtctgttggc
      481 tcttgtctta ggagcatatg gtttcttgga catattgatc ctggatcatt ctcatcagga
      541 ttactcttta ctgctatttt agaaactggg gtggtttgat ggaaagtatt ggtattggtc
      601 ttgttatcgt ttcacattcc aaacacattg cagaaggtgt tgttgaactg attagtaaag
      661 tagctaaaga tgttccgatt acttatgtag gaggaaccga gggcggagga attggaacga
      721 gttttgatca agtagatagg gttgtttccg aaaatccagc agatacttta cttgcctttt
      781 ttgacctagg ttctgctaaa atgaacttaa aaatggtgac tgatttcagt gataaaagta
      841 tcatcatcaa cagggttcca attgtagaag gtgcctataa tgcagctgct cttctgcagg
      901 ctggtgcaga actgtcagtt attcaaacac agttagcgga gcttgaaatc aataaataag
      961 gaattttact ataactcttt ttataggtaa gctattgatt atctcaacta taaaatgtta
     1021 agtaaatgat ttcaaaatta gaaagggatt gctttatgca gttccttttt attttaacag
     1081 gagtgaaact atagtgtttc taaattgtga atcaatcaaa actgattgtg atggggctat
     1141 tctagcttta gaatccttca aaaattaaaa tttaaggcaa tcaattactt ggaagagtat
     1201 gaaagcattt attttatagg aattctaggt ctagaattac acatatattt atgaagacgg
     1261 gggtgctcga tagttagtat tgttctattc tgaaagattt gagctgtcag ttgtatagaa
     1321 agtgttcgaa ttttttttaa gtgattaaat tagttaattg tatgaggtgc tttatgatat
     1381 aatgttttta atgaattttc agaaaggaaa acctcaaatt gttctacaaa tttctactct
     1441 tcgacctcga ccacactctt cttgattttg atgctgctga ggatgtggct ttgacccaac
     1501 ttctaaaaga agaaggagtt gcggatattc aggcttataa agattattac gttcctatga
     1561 acaaggctct ctggaaagac ttggagctga agaaaatcag taaacaagag ctggttaaca
     1621 cgcgcttttc tcgtttattt tctcattttg gacaggaaaa agacggtagt tttcttgccc
     1681 agcgttacca attttacctc gcccagcagg gacaaacact atcgggcgct catgatctct
     1741 tggacagcct cattgagcgt gattatgact tgtatgctgc gacaaatggc attactgcca
     1801 ttcagacagg acgtttggct caatctggtc tagcacctta tttcaatcaa gtctttatct
     1861 cagaacagtt gcaaactcaa aagccggatg ctctctttta tgaaaagatt ggccagcaaa
     1921 ttgctggatt tagtaaagaa aagacgctga tgattggaga ttctctaacc gccgacattc
     1981 aaggtggcaa taatgcgggg attgacacta tctggtataa tcctcatcac ctcgaaaatc
     2041 acacacaagc ccagccgact tacgaagtct attcttacca agacttgctg gattgtttag
     2101 ataaaaatat tcttgaaaag atcacatttt aaaggagatt agctaatgac tacaaaaaaa
     2161 gctaatatta ctattgaaga gtacattgaa atgtctgaag ttgattttaa tgaagctgtt
     2221 aattatgaat ttacatctga cacttgtcaa ttagcaaata gtatttatca atctcttttt
     2281 aagttttttg ataagaaaaa tttctctggc gatttaattt ttacttggaa atctccatca
     2341 ttagtcaaag aaggggatta tattgggaga agggattcac aagtagataa tcttagagta
     2401 ataggaaata tatttccgaa ttatcttact aatcgaaaat atagcctcaa tatgaatcgt
     2461 aatggctgta tgggagattt tcctcatgac ttttttgata tatacctaga tcatgtagca
     2521 aaatatgcct acgaacaaaa agttaataat attaaagagt attatccttt aaaaagagcg
     2581 attttacacc aagagaatgc attgtatttt cgattgtttt ctaattttga cgacttttta
     2641 gaaaaaaatt atttaaagac tatatggcaa gtttctaaag aaactccttt ttctgaaatg
     2701 gattttaata tatttaaaaa tatttcagaa aagataatct tcgaaagagg tagtaaaatg
     2761 cttaatgatt taaaaagtaa ttataaaaaa tagccagtct ttataaactg tattcacgta
     2821 ttcaaatcgt atatatagtc gatttattaa atctttagat aaactgtaaa aagtggtttc
     2881 catagccact ttttgctata atagaggcag taaaaatgaa ggagtcggct atggaacact
     2941 cgtcttggca tgctttgatt aaggcgcaat tacctgaggg ttatttcggg aaaatcaatc
     3001 agtttatgga gcaggtctat tctcagggga ttatttatcc acccaaggaa aaggtttttc
     3061 aggctctctt gacaacactg cttgaagaag ttaaggtggt aattctaggg caagacccct
     3121 atcacggacc aggtcaagcg cagggcttga gtttttctgt acctgactct atcccagctc
     3181 caccatcctt gcaaaatatc ttgaaagaat tgtcagatga tatcggagtt aagaaatctc
     3241 atgatttgac agcttgggct gagcaaggag tcttgcttct taatgcttgt ttgactgttc
     3301 ctgctggaca ggccaatggt catgctggtc aaatctggga gccttttact gatgctgtga
     3361 ttcaggtggt caatcatcta gatagaccag tcgtttttgt actctgggga gcttatgcac
     3421 gtaagaagaa ggcattagtt accaatcctc atcacttgat tatcgaatca gcccatccaa
     3481 gtcctttgtc ggtttataga ggattttggg gttccaagcc cttttccaag gccaatgcat
     3541 tcttaaaaga gacaggacaa gagccaatcg attggcttag ataaggagaa aatatgcctc
     3601 agttagcgac gatttgctac attgataatg ggaaagaact gctcatgctc catcgtaata
     3661 agaaacccaa tgatgtccat gaagggaaat ggattggtgt gggtggtaag ctagagagag
     3721 gagagacgcc ccaggaatgc gcggcgcgtg aaatccttga agaaacaggg ctcaaagcca
     3781 agccagttct aaaaggtgtc atcacttttc ctgaatttac accagattta gactggtaca
     3841 cctatgtttt taaggtgacg gagtttgagg gcgacttgat tgactgcaat gaggggacgc
     3901 tagaatgggt tccctatgat gaggttttga gcaagccgac ttgggaaggt gaccacacct
     3961 ttgttgagtg gcttttagag gataaaccct tcttttcagc caagtttgtt tatgatgggg
     4021 ataaattgtt ggatacccaa gttgatttct atgaataaag gagaaagcag atgctactaa
     4081 tcaaaaatgg tcgtgtaatg gatcccaagt ctggtttgga tcaagtttgt gatgtcttag
     4141 ttcaagatgg gaaaattatc aaaattgcgt ctgagatcac ggaagaagga gcagaaacga
     4201 ttgatgctac tggtcttgtg gttgctcctg gcttggtcga tattcatgtt catttccgtg
     4261 aacctggtca aacacataaa gaagacattc atactggtgc cctagcagcc gctgcaggtg
     4321 gttttactac tgtcgtcatg atggctaata ccagtccaac catttcagac gtggagactt
     4381 tgcaagcagt tctccagtca gctgccaaag agaagattaa tgtcaagaca gttgcgacca
     4441 ttactaaaaa ctttaatggt aaaaacttga ctgactttaa ggcactctta gaagctggtg
     4501 cggttggttt ctctgatgac ggtattccgc ttgagagcag taagattgtc aaggaagcca
     4561 tggaggaagc caaaaaactc aataccttta tcagccttca tgaggaagat ccaggtttga
     4621 acggtgttct tggctttaat gaaaatattg ctagagaaca tttccatatc tgcggtgcta
     4681 ctggggtggc tgagtacgct atgatggcgc gtgatgtcat gattgcctat gcaactaaag
     4741 cccatgttca catccagcat ttgtctaagg aagaaagtgt taaagtagtg gagtttgctc
     4801 aggggttagg tgcagaagtc acagcagaag tagcgccaca gcatttctct aagacagaag
     4861 cacttctttt aacacaaggt agcaatgcta agatgaatcc accgcttcgt ttggaatcag
     4921 accgtcgtgc cgttatcgaa ggtctcaaat caggtgtcat cacagttatt gcgactgacc
     4981 acgcgcctca tcatgtagat gaaaaaaatg ttgaggatat taccaaagcg ccatctggta
     5041 tgactggctt agaaacatcc ctgtctctca gcttgaccta tttagtagaa gctggtgagt
     5101 tgagcttgat ggaattactt gaaaaaatga catacaaccc agccaagctt tacaactttg
     5161 aagcaggtta cttggctgag aatggtccag cagatatcac tatttttgat gccaaggctg
     5221 accgctttgt ggactcccat tttgcttcca aagcagctaa ttcaccattc atcggtgaaa
     5281 ccttaaaagg gcaggttaaa tataccatct gtaagggaca aatcgtctat caagcttgat
     5341 aggagttaga atatgaatta ttttcgaaaa cgtagggaga gacaagcgaa atctaatagt
     5401 ggaatttact gtcccgcagc taatcgttcc aaaattcaat atgaaactaa agaaaaagct
     5461 gaccatgcgg ttcaatatga taacggaggt ttagttagaa gctattattg tcgtacatgt
     5521 gcgtgttggc atactacttc aaaatctaat aaacctccgc taagtttgaa aaactatggt
     5581 ctgaaactct ttggtttaga taaatcagaa tagaaagaga agtatgtata agacaaagtg
     5641 tttacgagag aagttagtat tatttttaaa aattttcttc ccaatcctga tctaccaatt
     5701 tgccaattat tctgcctctt ttgttgatac tgcaatgaca ggtcaataca acactatgga
     5761 cttggctggt gtatctatgg caaccagtat ctggaatcct ttctttacat ttctaacagg
     5821 gattgtgtca gccttggtgc ctatcattgg tcaccatctt ggtcgaggca aaaaggaaga
     5881 agttgcgtct gatttttacc aatttattta tttggccttg ggcctatctg tggtcttgct
     5941 ggggatggta cttttcttgg caccaataat cttgaatcat attgggttag aagcagcagt
     6001 agcggcagta gcggttcgct atctttggtt tttatctatc gggattatcc ccttgttgct
     6061 ctttagcgtc attcgttcct tgctggattc gctgggcttg accaaactgt ccatgtacct
     6121 catgcttttg ttactccctc tcaatagcgg atttaactat ctcttgattt acggtgcctt
     6181 tggtgttcca gaactgggag gggctggtgc tggtttagga acatccttgg cctactgggt
     6241 cttgcttggg atttctgttc tggttttatt taaacaggag aagctcaaag ccttacacct
     6301 tgagaaacga attccactta atatggataa cattaaggaa ggagttcgtt taggtctgcc
     6361 tattggggga actgtcttcg cggaagtggc tatcttttca gtggttggct tgattatggc
     6421 taagttttcg tccttgatta tagctagtca ccagtcagct atgaactttt caagtcttat
     6481 gtacgccttt cctatgagta tctcatcggc tatggctatt gtcgtttcct atgaagtggg
     6541 agccaagcga tttgatgatg cgaaaaccta tattggtcta ggaagatgga ctgctctcat
     6601 ttttgcggcc ttcaccctaa ccttccttta catttttagg ggaaatgtgg ccagtcttta
     6661 tggtaacgac ccaaaattta tcgatttgac agcgcgtttt ttaacttata gtcttttctt
     6721 ccagttagca gatacctttg cggcaccgct tcagggaatt ttgcgggggt ataaggatac
     6781 agttattcct ttttaccttg gtttgcttgg ttattggggc gtagcaatcc ctgtggctac
     6841 gctatttgat tccctaacag attttggagc ttattcttac tggatcggct tgattattag
     6901 tttgattgtg agtggggcgc tctaccgttg gcgtttaact gtgattatga agagatttga
     6961 atctttagca aaatccaaac gctaaaaagt ttgtgaaaaa atattcttga caagaaaatc
     7021 ccttgttttc acggggtttt cttttttatt ttgtgaaatt tcttttagaa aaactttgac
     7081 agtatttgcc aaaagcggta aaatagtaag gtaagaagaa agttagaaag gcaagaagat
     7141 gtcaacttta gataaaaatc ttttgctaga aatgttccgt aagatggaag aaatccgtcg
     7201 catggactta aaaattgcac aattagtaaa gaaagggaaa gtgccaggaa tgacgcactt
     7261 ttctgttggt gaagaggcag ctaacgtggg ggctatgtta gctctcaatc cagatgatct
     7321 gattacctca aaccaccgtg gacacgggca agctattgct aaagggattg acctcaacgg
     7381 aatgatggct gaaatccttg gtaaatacac tggaacctgt aaagggaaag gtggatctat
     7441 gcatatcgct gaccttgatg ctgggaacct tggtgccaat ggtatcgtag gtggtggtat
     7501 ggggatcgct gtcggtgcag ccctcagtca gcaaatgcaa aataccggta aaatcgttgt
     7561 ctgcttcttt ggagatggtg cgaccaatga aggtgttttc cacgaagcag tgaacatggc
     7621 ttctatctgg aacctgccag tcattttcta ttgcattaac aacggttacg gtatctctgc
     7681 ggatatcaag aaaatgacca atatagaaca tatccatcaa cgtagcgccg cttatggaat
     7741 tcctggaatg ttcatcgaag atggtaacaa tgtcatcgat gtctatgaag gatttcagaa
     7801 agctgtggac catgttcgca gtggcaatgg ttcagtcttg attgaaagtg taacttatcg
     7861 ctggctcggt cactcatcat ctgaccctgg taaatatcgt acgcgtgaag aagtggaatt
     7921 gtggaaacaa aaagatccaa tcgaaaacct ccgcaattac cttattgaaa ataacattgc
     7981 aagtgccgaa gaattggaag aaatccaagc gcaagtaaag gaagcagtag aagcttctgt
     8041 taaatttgca gaggaaagcc cattcccacc gcttgaatca gcctttgaag atatttacgc
     8101 agactaagga gaaagagata aaatggaaac aaaaacaatg tccttccgtg acaccattat
     8161 ccttgctatg tctgaggaaa tgcgtcgcga tgaaaatgtg ttcttgatgg gagaagatgt
     8221 cggtgtcttc ggaggagact tcggtacttc tgttggaatg cttgaagaat ttggtccaga
     8281 acgtgtccgt gactgtccga tttctgaagc tgccatctct ggagcagcag caggagcagc
     8341 catgacagga cttcgtccaa tcgtcgatat gaccttcatg gacttctctg ttattgccat
     8401 ggacaatatc gtcaaccaag ctgctaaaac acgttacatg tttggtggta aaggtcaggt
     8461 tccaatgact gttcgttgtg cagctggtaa cggagttggc tctgccgccc agcactcaca
     8521 atctctagag tcttggttta ctcacattcc aggacttaag gttgtggcac ctggaacacc
     8581 tgcggacatg aaaggcctgc ttaagtcttc tatccgtgat aacaacccag ttattatact
     8641 tgagtacaag tcagaattta accaaaaagg ggaagtgcca gttgatccag actacacaat
     8701 tccacttggg gttggtgaaa tcaaacgcca aggaacggat gtaacagttg ttacttatgg
     8761 aaaaatgctt cgccgtgtgg ttcaagctgc tgaagaatta gcagaagaag aaatttcagt
     8821 tgaaattgtt gacccacgta cccttgttcc gcttgataag gatatcatca taaactcagt
     8881 gaagaagact ggtaaggtta ttctggtcaa cgatgcccac aaaacaagtg gctatatcgg
     8941 tgaaatttca gctattattt cagaatcaga agcatttgac tatctagatg caccaatacg
     9001 ccgttgttca ggagaagatg tgccgatgcc ttatgcacaa aacctagaaa atgcaatgat
     9061 tccaacagtt gaaagtatca aagatgcaat ccgaaaaact tataacaaag actagagtta
     9121 cataatataa gttatgtaac taaaataaag ctgacgagaa actttgtatc ttttaggtgc
     9181 agagctcttc gtcattaata tcttatattc gagcacgggc taaaagctcg gaaaaaagat
     9241 aaatctcctt ggcttcatcg aagccatcgt cgatttccta tttttcagtc gcttttgacg
     9301 ccctttgtat cataaataga attggagagg tcatggctga tgacaagcta agagcgactc
     9361 ctgcagctag aaagttagcg gatgatttag ggataaacct ctacgacgtt tctggctcag
     9421 gtgcaaacgg tcgtgtccac aaagaagacg tggaaactta taaagacaca aacgtggttc
     9481 gcatttcgcc acttgcaaaa cgaattgccc tcgaacataa cattgcttgg caggaaatcc
     9541 aaggaaccgg tcatcgtggt aaaatcatga agaaggatgt tttggccctg cttcctgaaa
     9601 atatcgaaaa cgatagcatc aaatctcctg ctcagattga aaaagtggaa gaagtccctg
     9661 ataacgtaac accatatggt gaaatcgagc gtattccaat gacaccaatg cgtaaggtta
     9721 ttgcccaacg catggttgaa tcttacttga ctgcgccaac cttcaccctc aactatgaag
     9781 ttgatatgac tgaaatgttg gctcttcgta agaaggttct tgagccaatc atggaagcaa
     9841 ctgggaagaa gactactgta acagaccttc tttcgcttgc agttgttaag actcttatga
     9901 aacacccata catcaacgct tcattgacag aagatggcaa gactattatc actcacaact
     9961 atgtcaatct tgccatggca gttgggatgg ataatggatt gatgacacct gttgtttaca
    10021 atgctgagaa gatgagtctt tcagaactgg tggtagcctt taaggatgtt attggccgta
    10081 ccttggatgg taaattggct ccaagtgagt tacaaaattc aacattcaca atcagtaatt
    10141 tgggaatgtt tggtgttcag tcctttggtc cgattattaa ccaacccaac tcagctatcc
    10201 ttggtgtcag ttcgacaatc gagaagccag ttgtcgtcaa tggtgaaatt gtgattcgcc
    10261 caatcatgag tttaggatta accattgacc accgtgtcgt agatggtatg gctggtgcta
    10321 agtttatgaa ggacttgaaa gagttgattg aaacgccaat ctcaatgtta atttaagagc
    10381 aagagtattc atttttaaga tatagataaa ggaaggaaga catggcctta gaaataatta
    10441 tgccaaaagc cggcgtggat atgacagaag gacaaatcgt ccaatggaat aaaaaagtcg
    10501 gagaatttgt aaaagaagga gaaatccttt tggaaatcat gactgataaa gtcagcatgg
    10561 aattggaagc cgaagaagat gggtacttga ttgccattct caaaggagat ggtgaaactg
    10621 tccctgtaac ggaagttatc ggttaccttg gtgaagaaag ggaaaacatc ccaacagctg
    10681 gagcagcatc gccagaagct agccctgtac ctgtagcaag tacctcaaac gatgatggta
    10741 agagcgatga tgcttttgat atcgttgtga ttggtggagg tcctgctggt tatgttgcag
    10801 ccattaaagc tgcccaactc ggcggtaagg ttgcccttgt tgagaaatct gaacttggtg
    10861 gaacctgctt aaaccgtgga tgtattccaa ccaagaccta ccttcatagc gctgaaatta
    10921 ttgaaaatat cggtcatgct gcaaatcgtg gtatcgtgat tgaaaatcct aacttcactg
    10981 ttgatatgga aaaactttta gaaactaaat ctaaagttgt taatactctt gttggtggtg
    11041 ttgcaggact tcttcgtagc tacggagttg ctgttcataa aggaattggt acaatcacta
    11101 aagacaagaa cgtcttggta aatggttctg aattgcttga aaccaagaaa atcattcttg
    11161 ctggtggttc aaaagtcagc aagatcaacg tccctggtat ggaatctcca cttgtcatga
    11221 ctagtgatga cattcttgaa atgaacgaag tgccagaaag ccttgttatc atcggtggtg
    11281 gagttgtcgg tatcgaactc ggtcaggcct tcatgacatt tggttcaaaa gtgactgtta
    11341 tcgaaatgat ggaccgtata gttccagcta tggatgtgga agtttctaag aaccttcgct
    11401 tgatccttga gcgtaaagga atgaccatct tgactggtac taaactgcaa gaaatcattg
    11461 aggaaaatgg tcaacttcgt atcaaggttg aaggaaaaga cgatatcatc gcaagcaaag
    11521 ctcttctttc aattggtcgt atgccagacc ttgaaggtat tggagaggtt gagtttgaat
    11581 tggatcgtgg ttgtatcaag gtcaacgaat acatggaaac ttcagttcca ggcatttatg
    11641 caccaggtga catcaacggt actaagatgt tggctcacgc agctttccgc atgggtgaag
    11701 tttccgctga aaatgccctt aaaggaaatc atgcagttgc caaattgaat ttgactcctg
    11761 cagccatcta cactcttcct gaagtagcag cagtaggttt gacagaagaa caagcccgtg
    11821 agaaatacga tgttgccatc ggtaagttta actttgctgc taacggtcgt gctattgcat
    11881 ctgacgcagc tcaaggtttc gtaaaagtta tcgctgataa gaaatacgga gaaatccttg
    11941 gtgtacacat tattggtcct gcagccgcag aattaataaa cgaagcatca agcatcatcg
    12001 aaatggaaat cactgttgag gaaatgctga agaccatcca cgggcaccca acttactctg
    12061 aagtgatgta cgaagcgttt gcagatgttc taggaatggc catccattca cctaagaaaa
    12121 aataaaacga agatagatta gactggaagg ttatttccag tttctatcat ataaagtaaa
    12181 gggatatcat gaaatacatt atcaatcatt caaatgacac tgcttttaat attgccttgg
    12241 aagaatacgc ctttaaacac cttttggatg aggatcaaat cttcctactt tggattaaca
    12301 agccatctat cattgttggt cgtcaccaga acactattga agaaatcaac cgtgattatg
    12361 ttcgcgaaaa tggtattgag gtagttcgcc gtattagtgg tggtggagct gtttaccacg
    12421 atttaaataa cctcaactac acgatcatct ccaaagaaga tgaaaataag gcatttgact
    12481 tcaagagctt ctcaactccg gttatcaata ccttggctca actcggggtt aaagctgagt
    12541 tcacaggtcg taatgacctt gagattgatg gtaagaagtt ctgtggcaat gcccaagcct
    12601 atatcaacgg ccgtatcatg caccacggtt gcttgctctt tgacgttgat ttgtcagtcc
    12661 tcgcaaatgc ccttaaggtt tcaaaagata aatttgaatc aaaaggtgtg aaatccgtcc
    12721 gtgcccgtgt aaccaatatt atcaatgaat taccaaaaaa aatcacagtc gaaaaattcc
    12781 gtgatttact cttggaatac atgaaaaaag agtacccaga gatgactgaa tacgtctttt
    12841 cagaagaaga attggccgaa atcaatcgca tcaaggatac taagtttgga acttgggact
    12901 ggaactatgg taaatcacct gaatttaacg tccgtcgtgg aaccaaattc actagtggta
    12961 aggttgaagt ctttgctaac gttactgaat caaaaatcca agacatcaag atttatggtg
    13021 acttctttgg tattgaagac gttgctgcag tagaagctgt ccttcgtggg gtgaaatacg
    13081 aacgcgaaga tgttcttaag gcgctaaaaa ccattgatat cacacgctac ttcgctggta
    13141 ttagccgtga agaaatcgct gaagcggtag ttggataaat caaaaagaag ttggccaact
    13201 aaccaacttc tttttttgat atttatttac ataatttaaa atacgtaaaa tcataaacta
    13261 tccagagcat tcttttgttc atcactaaca atatgggtat agaggtcagt gacttgtgtg
    13321 ctagcatgtc ctagttggtg actgactaaa acttgtgatt tagtcgcatc atagagccta
    13381 gttgctagtg tatggcgcag tttatggggt gttacacgca ctttaaaatc ctctgagtat
    13441 ttagcaacca ttttctcaac gctagaagca tcgatacgat taggaacacc tctgtagaga
    13501 gttaaaaaaa gggctgtatc tgttttttcc gttttatagc gttgattccg aatggccaga
    13561 taattctcta aataaggttt agcaaaagca gcgacattga ctgagtcacg tttgccacct
    13621 tttcgagtaa catcaataac catcattttt agattgagat ctcttagatc tagattaaca
    13681 gcttcagata agcgaacacc agatgccaag agaagggcaa taatggctaa atctcgttct
    13741 ttatttttgt tgaatgatga gagagctcga tttgaaagct gttgtgggtg ctcttgatcg
    13801 atataagtta gaaaaccttc tgtttcatca cctagaaaga gtttttgctt gatattttca
    13861 gctctggcag caagggtttc tttctttttc ttggttgaaa cttttttcat tacattacga
    13921 tagaaataag gttccccctg atcgttttca acctcctcgg ttagatactt gtaaagacta
    13981 gaaagtgctg ataaggttcg attgatagtt gtctgtgaaa caccttgttt tgttgtatta
    14041 gcattcagca agggacgttc acgtagataa aggataaagg attccatgtc tttcttagac
    14101 atattttcca aaactgataa aggaatatcg gatattttat cagcgtttga aataccagac
    14161 tccaaaaccc agctgaaaaa tcggtcatat tccttaaggt attcgtacag ggttgtaaaa
    14221 ctgtagggca cagccagttt agattggtag tattccagaa cataccaggg catgagttgt
    14281 tttagtttgt cgattcgttc cagtaaaatc tcacgtttca tgtattttct ccataattaa
    14341 gtatactagt agtatagcat agacttgtac atttttcaag aaaattatag tttttcagaa
    14401 agatgttata ggagtttttc aaagtgataa aaagacttag acctacaaac aaaacagaat
    14461 aaggaaaata ataaaaatct cacccactaa acttctgtta atactacata gctagaaatt
    14521 ggtttgattg tcctgattgt tttatcctat ttctatttca tttcactata taattgctat
    14581 tgttttcttt ttcatgattt taatcttact gtacagattt gatacagtaa actcctttct
    14641 agctttatac tttatcattt ctaacttaat tatagtctta tttttaataa agttcaatta
    14701 tttatatgta aaattcctca tcagtaaaaa ataaccgatc tcatttctga gaatcggttt
    14761 tctaaataaa tcaagccgaa taaatcaagc cgatcattta cataacataa attatgtaaa
    14821 tgatcgtact acaacaacaa atctttgact tttccaattt cactttttgg aataaccagg
    14881 tgaatcatat cacccagata cattctggtt gagccgttaa ctgtttggct cttgccatta
    14941 tggacttgag ttgtgatgag gacgttgtgt ggtaagttga gttcatgaac ttgtttccca
    15001 gcaattttat cagaaactgg tatttcgata agtgtaactt ctccttcgct agatacttct
    15061 tctggaagca ttttttccag catggcttca tagactggcg tacctttgag caaatccatg
    15121 ataatataag aaacaagagt gacaagacca agtggcatga ggttgcgaat atctcctacc
    15181 atctcagtta cgaggatcat agcagttaag ggagcttttg atatggctcc aaaatagcca
    15241 ctcattccta gaatgacaaa tatagggaat tgctcttgac tgacaagtcc aagattgaca
    15301 cagataacac caactaaggc accaagcaaa gaaccaagag ctaaaatggg gaggaaaatt
    15361 cctcctggca gtccacttcc atagctaatc atactccaaa taaagcggat taaaaagtaa
    15421 gctaataaaa cttggaaact aaaattttgt tcagttaaag aaaggacaag ctgatttccg
    15481 ccaccaatga tttgaggtaa gaagattccg actggtatga taaggataaa agccaagatg
    15541 ggataataag ccctatccaa atggattttt tgaccaatca agtcataaac tcttccaacg
    15601 tttaatacag ctttctcata gagaaaacct gaaaatccaa ggaaaattcc catgacgaga
    15661 tatatccaat actgatctag ggtcatggga ggaatgttat ctggcatatc caatactggt
    15721 gtcaaaccga acatgagtag agacacaaag tttgctacga tgctggctgc tagagttgag
    15781 acccagaaaa agcgcgaaaa atggtgatag acttcttcta caacaaagag aagtgctgca
    15841 ataggagcat taaaggctgc ggctaaacct gctgcagctc cactggcaat caaggaacgt
    15901 tcctctactg gactggattt gagccacttg gcaattcctt taccaccaac tgctccaagt
    15961 tgaatgctgg gtccctctcg acccagcatg agtccactgg caatagcaag aatacctagc
    16021 acatattttt tccaaagaat gccccaccag ttgagggaca tgaggccttt cagttcggct
    16081 tcgacttgag gaattcctga gcctttaata tctttttctg accgtgttag tttggcactg
    16141 agccaacaga tgagtatata aaacaaaacc agtacaaaaa gattgcgcac taagtaccct
    16201 tgatcttgat aaactccttg tatcaggtgg aagccctttt caattaagaa acgaaaggat
    16261 ccgacgataa ttccaacgat gaggccgaca atgattcctc gaccaacttg ggatagtata
    16321 gtgctggatg caaaggcgaa ttctttctta gaacggacta tttccgactg ttcctccatg
    16381 gtatttcctt tcaattaatt ttctttttta cctaaaacca gtgatttaac gggttcaaag
    16441 ctggttcggt gaattggggt aactcctagt tttgtgaggc cttccagatg tttagctgtg
    16501 ccatatcctg cattagtagc gaaatcatag ccagggaact gctgatcgta ttccttcatc
    16561 aattcatcac gtgttacctt ggctactata gatgctgctg cgatagagag ggagttggca
    16621 tctcctttga taatggaggt ttgtgaaatg ggcaagtcca gtttcatggc atcaatcaaa
    16681 aggtgctctg gttgagggct gagctgggag attgcttctt gcatggctag tttggttgct
    16741 tcatagatgt tgacttggtc gatgacctga ttatctatga taccaattcc aatcgacaag
    16801 gcttggtctt gaacggcttg gaaaatctcc agatgtttct ttttaggaat tttcttgctg
    16861 tcgttgagac ctttaatctt acaattttta ggtaaaatga cggccgcagc gactacagga
    16921 ccagcaagag gaccacgacc aacctcatca atacctacaa ttaaggtcaa tccttgctta
    16981 taaagttctt tttcataaga aagcatggat tccaagcgca aattttcatc taattcagct
    17041 tgaatggctc ttttacgctt gctgatttcc ttttgaactc ctgagcgatt atccttttca
    17101 agctctaaaa aaatagggct ttctaactcc ttgactgtca caaggagttc tttgatttct
    17161 ttaatcgttg ccatcgaggt cttccaatgt atctaaggta tagttaccga gtttgccatc
    17221 acggacttcc ttcacgaaga gactgtaaaa acggtcatag tcatcacgga aaccgagggc
    17281 gcgggtcata tccataataa tcacaggcgc ttcttcttca attttcattt gtttgaagcg
    17341 ttcagccagc ttttctggat aatgttcttt gaaataattg ataccaaaaa tggtaacctc
    17401 atccatagga agcaactgat ccttgatagc tccagtcaat gccaacttaa gtgcaacagt
    17461 ttcatcctca aacttaggcc agagaatccc cggtgtatcc aagatttcca gatctttatt
    17521 ggttttaagc cattgttgac cttttgtgac ccctggcttg tttccaacaa cagcaatctt
    17581 tttaccagcc aaacggttca tcagagtgga tttaccagcg tttggaatcc cgataatcat
    17641 ggtacgcaag gtttcaatct gaatcccacg ttctttctgg cgagcaatct tatcagccat
    17701 gagcttcttg gccgcatctg ttacaacttt tacagtcact tgctctttgg agttgatagc
    17761 tagcgtctgg atttcttgtg attcaaaata ctgacaccat tccttggtca ttgctggatc
    17821 agccaagtcg gccttgttta aaatcaagag ttttggttta tcaccaacaa tcttggtcaa
    17881 cataggattt tgactagata gaggcaagcg tgcatctact aaaatcgtca caaaatcaac
    17941 aaattttaaa ttttcctgca cctgtcgacg cgctttagac atgtgaccag gaaaccattg
    18001 aatagtagcc attgagtttt ttcctttcgt agctctgaag ctgttaatct agaactaaga
    18061 gatctcaatc taaaaatgaa tgatgtccaa acagttcttg ttttatgata taaaaatcta
    18121 ctttatatta tatcatgcct tctttatttt gtccgatgat agccttttac cctatctttt
    18181 accctatata gaaaaaagcc atcaaatgat gacttttcag agggagcaaa aaactgtcct
    18241 ctttatattt taaacattta aatgtcttct ttaaacagtt tattaaagaa accgtctgtg
    18301 tttttaagaa gggctttgaa tactttggat ttcaagtcta ctgtattttt gaaatgatct
    18361 ttaattttcg gatctgacat accatcaata tctttttgaa cagcttcagc aaataaagtt
    18421 ttcaactgag cataatttgt aatttgacga ccatcaattt caatagcagt aaatcctttt
    18481 tctgcttttg acttaacatc tttgaagtat tgtttcttcc actcttcaag attattgaat
    18541 ttatccttag atactttctt gataatgaaa tcatcaccca ataatttttt attggttttg
    18601 tcagcttcgc cttgatattt gctagatgca taactaatga atccattttc ataaccaaaa
    18661 tagccccaca tacggaaagt attatgcttg aatgatgcag ctccaggtgc tccttggcta
    18721 gtattaccac catagatacc ggtcattata ttaatattta cgtaagcact atcaaaatct
    18781 tctggattat atgttctgtc actaggagcg ccatgttttg tcatcaaatt attgttgact
    18841 aaatcatcaa tgttgttgat aacaattttc ttcttctcat cttcagttaa ttcacgaact
    18901 ttatcaaatt gatgtagctc tccatttttg cgatattgtc tatccatttt cttgaaccat
    18961 cgactaatat taccatgtaa tttagggata acagcatcag cctcaagatg gtctaacatc
    19021 ataagagcat cattataatt tctcatataa cggtcgatat cttcacgagt tttcaattta
    19081 tctggatcat aattatacca ttggtcaccg tcattttcac gatgataagc catgttaaga
    19141 ccaagagcac catattcacc gttaccagat ttatcaggtg tctgcaacat accttgcgca
    19201 taggcttcaa cgtctgtacc ttgacggtgt ctatgcccac cgaagtaaag cattctatcg
    19261 tttacgtgtg ttgtttcgtg agtaaaggct gaaataccaa acggactaat catatttgtt
    19321 cccatgaaat aaacttggtc attattattg ggatcttgga aaatagatgc catagctccc
    19381 atgtaccaat ttgtagtatg ataacgccaa gtaggtccat ataattcacg aataggtgca
    19441 attggtttat tattcttatc ataacccata cgatttacac cttcgacgtt atgatagttt
    19501 tggttatccc aaacaggtgt tggaacccta ttttgactct tgagtaattg gtcacgtacg
    19561 cttggcaatg ctaaacgcga ccagaagtca agataagttt gttgtgcgtg agcaacttct
    19621 ttaattttat ctttaaatgc ttctcgttca gcttctgtat acttaccata tttttcaaaa
    19681 gagctataag ccattgtatt gtaagtcgaa atcaagaaca tatgtgcatt cttaagagtt
    19741 aatagaggta ggatcatacg attatgaaca ccattattca aaccatcaaa tgcacgatgt
    19801 cgtttattaa caaaatctgg gttcgttgtt ttaggctcca caatgtatac gttcttagcc
    19861 gcatggataa accaatcatt taaatcagta tcgttagtga agagacgcat gttgtaatct
    19921 aagaagccat gtaattcaga cttaccaata gttccaccaa tcatatcacg ataagcatcc
    19981 aaagttctgt cacccttgat atttcgctca cttgatccaa ttcgaatcaa gaagtcaaga
    20041 aggtcaactg acttaccata gaaatcaggt ttaaacatca tcaagttttt gatagtcata
    20101 tccccatact ttatatcata gtaacgatta aggtaagtaa gagccatcac gattttagct
    20161 ttattttcat ccaccttctt aacaagtgct ttcatagctg cttcgtcact atttaattga
    20221 tggtcagcat tttcaatcaa agatttgacc aatttatcaa gattagcttt cgtttcagaa
    20281 aaactttctt cgaaataaag gtctcggata taaccattct tacgctcatc cgaattagca
    20341 ttaggatctc tagatgtatc tcgtttatcc atcaaagcac ggacttcggg agaaattaat
    20401 tcaacagttg ctaacctatc tttaatgtct ttaatcaatt gatcacgatt tttatcaacc
    20461 atgtttggtg tataaacaat gtcatctaat ccatcgatac tatactcacg aacttgcgct
    20521 actttagact ctttttgatg aacagctttg atttctttag tcttatctgc atagtgaatc
    20581 atcacatgat caatatctga taaatcggtc acgaattgac catccttcat acccgtaaca
    20641 gaaaggactt ctttcttagc taagtttgaa tcttctgcaa gtttgttacc ttgattgaca
    20701 atccattctt tgttataaaa tggttgcagt ttctcaatat tacgataagc cagatctcga
    20761 tctactttat agtcttgggt tgacttatat tcatcttctc ttctggttaa acgatttaag
    20821 cgattgacca caggttcatt gatttcgtat ttatctgcgg taattcctgt agcttcaatt
    20881 ttagattttg cctcttcctc agaaataggt ctgatacgat ttttatcttt tgaacgctgg
    20941 tagctagaat gcccatcact aacacctatt acaacataat ttcgtcttac attatctcct
    21001 gtccagtagc catcatcata atcaatatca ctagaaccat agaaaatttc accattaggt
    21061 accttcatca tggaaactga atcttcgaca gaaccgtggt gcttcatgct tcctacaaca
    21121 ccaccacttt caatcgcctc agttacttga attgttccct tagcaataga ttttttgatt
    21181 gctccttcct gacgaacagt attgttattt ccttcatttt gtgtccaata agcaatgccc
    21241 gcagccttgg ctttcttgcc aataagattt gcgttaacat acgcgcgttc gacgagtcct
    21301 ttccagttct caccaacgat accagtcaag aattgtccac catcgccgac agaagttacg
    21361 ttaccgataa aggccacatt tctgagtgta ccttggttat caatcttatc aataaatcca
    21421 gatacccaat ctttacctac tatattacct ttaaccttaa cattttcaat ggtagttcca
    21481 cctttaataa tattcgctac agctgcaact tggttcgccc atggcatatt tatgtcaaca
    21541 ttaccaagat taatattctt aatcgttcca ccaataacat tgccaaataa cggacgtgac
    21601 aagttatgaa tggtatagtg attatcacca tcactcaaga gcttaccttt gaaatctttc
    21661 gtaacatatg atttaccaaa tgctgataca tttgtggcat taaggtcagc acccaattta
    21721 aactcgtcat ttggatgttc ttgcatatct ctcacaagtt cattgaaatt gtaatataca
    21781 ttattgactt ttggaactgg tttttcaatg taatgaatgt attcatttct agtcttagat
    21841 ggatcgacat gttgaattaa atcttgagcg cttgctgtaa ttttataaag ttctttttct
    21901 ttttcagtta ctaactcaat cttatcaact gctaaacgag ttactttatt atcacgacta
    21961 gtgattttta agtacatttt cttcacatct tcatcagaag gtttttcgct catgaaatca
    22021 ctaggtattt cagtaccatc atcatttacc ttcactaaat tagtagatga aatattttta
    22081 atttcgacct ttttcaactc caaacgcaaa gttttttcat ccagtttaga cgtttcagaa
    22141 ccttgaccac gatcataaat cattgttgtt gcaatcttat aatctttaaa caaatccaaa
    22201 ttttgtacag cgtcagttaa tttttcttta gataaatcaa cctttttaac tactgtatca
    22261 ccatctttaa tttcagctat aatacttgat atttcagcat tatctttatt atcaagctca
    22321 taatttaagt tggcagaacg attcatagca tcttctgtta ctttggtcaa ggtcaaaacg
    22381 ggaactgttt tttcttttgg attttctttt gtacctttta caagaatttt aggtttcatt
    22441 tctttcaaaa ttgttaccgt ttcaactggt tcactaattt ttttgccatg taactcttca
    22501 tagctagtaa caatttgacg ttcgccatcc tcaccaactt ctttaacaga atcatcgcct
    22561 ataaatttgc taggatcaga ttcttctata gtggttttag gaatagtctc tgtacgaata
    22621 tcggtatgta aagaaggcaa ctcttctctt tctgatgcaa cttctgaaac tgtagatatt
    22681 ggttcagtat actctggaat gtcgttaaca ggtggttcaa tcaagtttcc attttcatcc
    22741 actcctgttg tacctactgg ttcagtgtat gctagtttct catgaacttc aggctcaaca
    22801 aggtttgcac ctattggttg cgtatagtca ggcttctcat gaacttctgg ttcgcctttg
    22861 tcagtcacaa cagcttctgg taatgtcggt tgtacttccg gttcgccttt gtcagtcaca
    22921 acagcttcgg gtaaggctgg ttgaacctcc ggttcccctt tctctgttac aactttgggt
    22981 tgctcaactg gcgaaacagt tgatgctgga gaaaccgacg aaacagtttt atcatcaagc
    23041 tccaagtaac caacatatct gtaaccagaa atttgcaaca caccatcacg tccagactca
    23101 tggatgttag cattcaaatt aagtgctgaa gcagttgata gtgtaactaa acctgtcgcc
    23161 cctacaatca aaaatgtagc tattttttta tttctattat cttttgtgat aatcacaata
    23221 agactcccga tagctaacaa acccaatgca gtcataatag attgagaact gcctgtgttt
    23281 ggtagtgcgt ctttttcata atccaaagca tatgactctt tggattcatc aggtctacct
    23341 tgtttgagtt gatcacgttc agtttgtgtc aaactactat aatctaagta atgataagtc
    23401 gatgcaccaa taactgacgg tgcaaataaa agactcccca agaataccga accaacaata
    23461 ccctttattt tccgaatgga aaatttatct ttttttaata atgacaattc taatcctcca
    23521 cattcacttt ttatttccta atagtaaaca ctatttttta ttctcaaaaa ttgaacttct
    23581 aaaatcattt gtttggtcaa gataagcttt atatattgct tttttcagtt taagaactct
    23641 actatttgtt tctgggtaaa attttgctac gtcatcttgc gcatcatctc tcactgcttc
    23701 gacaatcatt ctctctagta cacctatatc cgtaaccgat acatttcgtt gacgactcaa
    23761 tggattatta ggattaataa agttaactct atttagttta ctgaattgtt tttctctttc
    23821 cttatacata tccttcttga attgtgtcca agttttatat tgaccattaa atactttttc
    23881 aagtactaat tcatctgtaa ctaaacctac ttctttacca taagaattaa tcttacttcc
    23941 cgccgctttt gcatcttttt catattgatt tgagatataa ggtaccatgc cctctttata
    24001 tccttttgca gctaataatt cgaatgctat acggcgtccc attaaatcac caggagtccc
    24061 tttctctcca ctaagagctg aataaatcgg tgaaaataaa tcaattgtat aataaccatt
    24121 tctcttatat tcttggtctt tgtaccctct gctagtaata atatcatttt caattaaact
    24181 atcaaaagaa tttaatttat taacttcatc catcgttaat ctgcgaacaa catttgtcgc
    24241 gtatacatta ttaccgtctt gatcaagatc aaatttattt tcaatttttc ttagtaactc
    24301 atatttttga tttgtttcta aattagctac agcttttcct tctaaatatt ctaacatata
    24361 aattacatca aacatattat gcatataatt atgtaggtct tctgcactat taaatcgttg
    24421 agttggatca gctacttgaa gtcttgttga attttctgaa tcctcatatt tcaagacaga
    24481 gttaattgtt attgttggat catatggatg atccggagct tgtaataatc cttttgcata
    24541 aaactcaggt cctaatccgc ttcttcttcc atatcctcca agataaatct ctctatctga
    24601 gttatgtgtc atttcatgag tatatgttac agctccatct ttatccaaca tacgatatgc
    24661 catataatag aatgcatctc cggtagcata tgctccgtgt ccattatgaa caacattatt
    24721 tcccgcaggt ccaaagaagt attttatagc tggatgatca gtttcaaaag tagcttgatg
    24781 agttactttg tctttatctt tgtcagtacc aaatttgaaa gcatcatata ctagaatact
    24841 tctatataat ttttctttat tatcgttatc taatatctta taccaataat cataatgatc
    24901 tctaaatcgt ttagccgctt ctttggcgtt atcttctaca aatttgttta acttttctcc
    24961 cttaggatat tctgaacttc tatatctgtc ataggctcca aatccaatag tagaaatatt
    25021 cgctatcata aacactgttt tttcttcagg taaagttaat agtggtaaga ccatactttg
    25081 atatttccaa gatggattag ttaatctatc atatacccca atagaatatt tagttccctc
    25141 ttttccttgt ttttctcttc cctcttcaat tgtagatttt tcttctacaa tatatgcttt
    25201 tgtttgtttt ttaaaccact cattgttaga aattgttggt aagaatactt ttctatatcc
    25261 ttctaatgct ttaaataaac tttcagttcc ataatttttc gctaataata cattataagt
    25321 aattacatta ttttttgcta ataaattgtt aaatccagat ttacctaact caataacatt
    25381 atctaatgca gaactatttg atttaccaaa gaaatccaag tggtacatta ttaaatcttt
    25441 agcattggtt tctccataat taaaattata ccagcgttct aaatacgtta atcctaacaa
    25501 taaggcttcc ttattatttt ttattttctc aattacataa ttatctatta ccttattgtt
    25561 attttccact attgcagcat ctgcagtaag tagttttgat aaactgtctt ctatatttgc
    25621 ttttgttttt tcaaattgtt cacctaaata taactctgtt aattttatat taccagaaat
    25681 atctaatact tttctaacgt cagctgaact atattgaaca gatttcagat catttaaaat
    25741 agtttttaca atattattat aatcatgcag cattgtatta ggtgtataca ttaattttgt
    25801 attagctata tcatactcag caactttaga gaaatcattc ttatatgcaa tatttaatac
    25861 tcgtgatttg ttaccttcaa aatgtaataa caatttgttt atttcttgtt tatttttatt
    25921 aatatcagtt attacttcat tgttcttcat aggaacaact gatagaagtt ttttagtaaa
    25981 taagtcactg ttatcctcta ctaaattacc atacttaact attgtttctc tgttatagaa
    26041 aggaagtaat ttttcaatat ttttatatac ttgttctctc gactgttggt aacctgttac
    26101 ttcattgtaa ttagtattgt atcttgaagt aaaatcaaaa tcttctactt tagtgctgtg
    26161 tttagaaacc aattctacct ttttctcttt tactttatca gcatctaata ccgtacctct
    26221 ttgtacatct gaatctttag tcacaacctc atcatcttct tgtactacgt ttactacctt
    26281 attattttta ttgctatatg tttcaatcgt ttttattcca ttgaaattat agccagctat
    26341 agcattacca ttcgtaacat tgacatcact taaaacatat gatagtttac ctgatttact
    26401 tacatcttgt gaatctctat cccaaagatt acctgcaact cccccaactt taccaaagtg
    26461 tcgcacattg ttaacatttc cttcaacata gctatactta attgtcgcac ttttctcaac
    26521 aactccggct ataccaccaa caatttgatc tcctgatttt gcattagagg ctatgtcaat
    26581 cgatgctatt gatttctcta tagaagcaag cgaaccagaa agtttaccta ctaaaccacc
    26641 aatttcatac cctgcagttg tatcatatgt gttagttatt ctgcctgtaa aactactatt
    26701 agaaattctc gagttatcta cttttgaaac caatccacca attccacgtt caccagctat
    26761 aataccatca gaatgaacat tatctataag agtattgtat tttgcttctt tcgatattgt
    26821 agcagcatct tctttagaag aaacattcgc ttcttttatt gaaagattct gaatagtagc
    26881 ggtgtttaga gttttaaata aaggtttttt caagttataa atagcataat acttaccatt
    26941 atttttacct attaattttc cgtaaaattc attttttaca taactttctt gatcatccgg
    27001 aagttcaact tcacgagcat ccatagttgc acctaaatgg aatgttccat tagggtcact
    27061 attcattgca tcaactaaat ttttaaatga tgtatagacg ccagtttcac tttgctgagt
    27121 ttttggtaaa taatatgtat agtcattcga aataacattg ttttcgtgtt gaattagatt
    27181 ttctgcatga gccacaattt tgtatacttc tttattgttt tttgttgtac tttcaatttt
    27241 agtaacaggc aacattatat ctttaaaatt ttctgatttt accttcatga aatacttcaa
    27301 tgaactatct aaagcaccat ctacagccgt aatatgtcga tatttattat tttctaccgt
    27361 atataattcc acgtttgaaa catttctaag ttctagtttc ttgtcgactt gtttttcttc
    27421 tttaatttta tctttaggac gttccgattc cccatttgta gagcttgccc cattttcagg
    27481 tttagtatct tctgcactag gctgttcgat tttaccagta tattctttcg gtgcttctac
    27541 tttctctggc tcgactatcg atccggcttg tacccctgtg tattctggta gtggtgctac
    27601 ctgctctggt tcaacaatag cgctggcttg tggtcctgta tattctggaa gcggtgctac
    27661 ctgtttaggt tcacctttat cacttaccac agtatctggc gactctggtt gaacctcagt
    27721 ctcacctttg tcagtcacaa ccgcttccgg tagctctggt tggactgctg gttcaccttt
    27781 atcacttacc acagtatctg gcgactctgg ttgaacctca gtctcacctt tgtcggttat
    27841 aactgctttg gacaacgctg gttgaacttc tggtacgcct ttgtcactta ctacagcttc
    27901 gggcaactca ggctgaattg cgggttcaac aatagctcca gactgtacgt ccttatgttc
    27961 tacaccagtc tcaggttgtt cctttataac ttgagttttt ttagtacctt tttcgactat
    28021 tcttggaata ggcgcagtcg ttgaagttga aacaatttct cgcgaaactt cttccttgtt
    28081 tacagagaat attctgacga tttcaacttt cttacctaat ttaccttctt gttttactct
    28141 tacaattcct tcaactaaat caggattttc ttgaatttct tcttgaaaat ctatttttat
    28201 ctctatagtt tcctcacgat ataagagttc aggtttgttc aattgacctg ataaaacttc
    28261 atcctgtgga tttaatgtat ttaccccagt cttttctttt ggagaaatct tctcctcttt
    28321 cttcgtttct agattcttat gttcggctaa ttgttcttga gaatctgaag attgtttctc
    28381 ttcttttctt ggattgatta attcagtaga gaaaggtttt tcaactactt gaacttctgt
    28441 cggcttagtt gaagaaacag gtgtttgttc ctgaatagct tgtactgttg atggatggtc
    28501 tacaaaattt ggtgtaacat tataatccac cttttgttgt tttgtaggag tggctgctga
    28561 tttttcttga ttacttactt caaaatcaga agtcgttttt ccctctttga tatatccaat
    28621 ataagtgtaa cctgaaatct ctttaggaag aggtaatttt tctccagagg tcaattcata
    28681 gtccgtattg taatttagca aaagatgatt ttctaaagca tggactgaaa ctaagacacc
    28741 atttcctatt cccgcaacca atactaaatg taataccgtt ttattcttaa cctttttctt
    28801 ggaaacagca aaaattaaaa ttcccagagc agctaagcta gcaccagcaa ctagggcttg
    28861 cctctcattc ttgcttccag tatttggtaa ttccgccagt tgattttgag aatttaactt
    28921 ataaacaaga taataagttt catcatcatt ctccacgtat gtcggaatat catagacaag
    28981 ctgcttcttt tcttctgatg atagctctga atctgccaca tatttatagt gaactcccgc
    29041 agtttcttga gcatccacag atgaactagc taatacagac ataaaaaata aacttgaaat
    29101 cgttgcagat acaagtccta ctgataattt tctaaatgaa aaacgctctt gtttttcacc
    29161 aaaatacttt tccattattc ctccttgaaa taaaatttat atatgttaca aagaccttta
    29221 ttatattagt gtattatcta ttatctatag aaaaggcagt ataccttaat tatactctta
    29281 atttacaaaa aagtcttaaa attgagatgc gctttcatac tttgttttat attatttggg
    29341 ggtacaataa cacctaccat gaaatttaca cggtaggtgt tactcatatc actaatcgtt
    29401 ctaaaaatgg tttgaggcag ttgaggagaa ttccttctat ccagcttcct tgtgctgatg
    29461 agcgatagtc ttcctgcagg ctttttttta gaaaatctcg gacttgttct ggtgcgattt
    29521 caaattcaaa ggctttcatt ttatagaaaa agtcgatgag atgatctgac aggtattcag
    29581 ttgaaaaggg tacttcacca ttttttcgat attctaataa gagcctagaa aatcgagctt
    29641 tttcttcagg aagctcacga aaataggaat tgaggagcca agtctgtttc tgttttcttt
    29701 caattggatc ctgactggca attcgttggt ctttttccag ctctttttgg tattgtttgg
    29761 ccttaatagc ccgttctgct ctatttttac caaaaagaat tttttcccac ttgcgttctt
    29821 cttgagtcag ggtctctgta aagccaaagt aatcttgata agcacgctct gcgggtccca
    29881 tggctagaac cagattgtct gcatattgct tggcgatttt atccctcttc ttgcgttctt
    29941 tctctgcctg gatacggagt tcttgttcgt agtcaatttt ctccttgcct agcttgacaa
    30001 ggtagagttg gtcatccgat ttcccaagta aaaagggttt gatacacttt tcaaggactt
    30061 cttccatccg agcctttttc tttggttccg ccttggtcca acttcctccc tgaaagactt
    30121 ctaggaaaag ctggtagtct ctctcaggcg caaattgatt gccacgattg ggtttgaaaa
    30181 cacctttttc ccagagccat tttagaagtc gctcgtcaaa gtcactttta ttgaccttga
    30241 ttttttcctt tttctgagct tttctggtta gattttcaac ctttctgagc agtttttctt
    30301 cctcttccaa ttgctggtca agggacaatc gatgaaaatg acgaacacag tcgctaccaa
    30361 ttggaaagag gcgttggcct gtgacaccgt taaagagttc ataagcgtat ttgatgacat
    30421 ttccacagac acaaatgcta cggccgatac cgttaaaaat caaggaaact tcattccatt
    30481 ccttggtagc ttgttcccaa gtatccgctt tcgaagcctg taaaactgca tcgtgcaggg
    30541 attttctaac tggaagtgtc atgaggtctc ctttctaata ctcaataaaa atcaaagagc
    30601 aaactagaaa gctagccgca gtcagctcaa aacactgttt tgaggttgta gatagaactg
    30661 acgaagtcag ctcaaaacac tgttttgagg ttgtggatag aactgacgaa gtcagtaacc
    30721 atatatacag caaggcgaag ctgacgtggt ttgaagagat tttcaaagag tataagttat
    30781 acttttacaa cttgaacctc gtctttaccg agtaaaatca agtatttttc aatattttca
    30841 atcgaatagg ctcgtgataa agcctcttcg tatagagcta actgaccacg atagcggtct
    30901 acgagttgac ttggttcatc atagcggtct gtcttgtagt cgaacagaac aattttgttt
    30961 tcgtaaagca gatagccatc aaggatacca cggacaacaa agtcttcctg actcttttgg
    31021 tctcgtttga gcatggagaa aggttgctcg cgatagagat ggtcggtatt agcaagaatt
    31081 tcctgaccga gtactgtgtc aaagaaagca agaattttat caagattgat cttgtctctg
    31141 acagcttggc tagtttgaac gtgtttgagt gtttctgtta ggctagcaag ggttagttgc
    31201 tggctgaggt caattctctg catgagttcg tgagtagcac taccaatctc agctccagtt
    31261 accttttctt tggttgaaaa atctggcaaa tcgaagctga ttttcttgcc tactgactga
    31321 ccttgaccag caatctcgac accttccata tccataactg gttcgtagaa tttcttgatt
    31381 tgacttgggg tttgaacact aggaagttca atagctgcgc ggtgaagagt attataaact
    31441 tccacctcct tcagcatttc cagagcttct ttgatggtat ctgactgacg attgtctgct
    31501 tgggagctat cttggagagg actcttggtt tccaactctc cgatagcttc tctggtcaac
    31561 tgatcttcgc caataaaacg ataactaaag ttgagcttgt ccttagtaaa cactttactg
    31621 atagcccaaa gccaatcttg gaaattccgt gcttgcagtc tagtattgct atttagtttc
    31681 ccatttttgg ctgctgggta ttccttggat tccagctttt cacgagaacc cttgccgaca
    31741 agatagagct ttttctcagc ccgcgtcata gcaacataca gcaaacgcat ctgctcagaa
    31801 tagcttgcta gctgtaattc ctcttcgttc tgcctatagg tcagactagg aatggagagt
    31861 ttgatggttt taggatagtg gtcttctact gcccctgtct ccatcttggc aatatatttg
    31921 acaccaagac cattctgacg actgagaatg acttctgaca tagagtcttg cttgttgaaa
    31981 tcttgatcca tattgaggat aaagacgtaa ggaaactcca gccctttact cttgtggatg
    32041 gtcatgagct ctactgcatc ttttggcggt gcgacggcca cgcttgccaa atcgtgctgg
    32101 gcttctaaga cttggtcaat catacgaata aaacgcgaca aacctttgaa attgctcttt
    32161 tcaaattgat cagcacgcag tgctagggca tagagattgg cctgcctagc aggaccattc
    32221 ggcaaagccc caacatagtc ataataaaaa cggtcgttgt aaatcttcca aatcaagtca
    32281 tagagagagt ggggtttggc atacaagcgc caagaagcta ggatatccat gaattgcttt
    32341 agtttttcag ctagagctgt gtgaatcaag cctttttgac tacttgccat tttttgtgca
    32401 ttgaccagtt tctcatagag attttcgtgg actttatcct ctgctttctg aagggacaaa
    32461 cgtgctagct catcctcatc aaaacaaaac attggagact tcataagggc aaccaaggcg
    32521 tagtcttgca ggggattgtg aatgacacga agagtgtcta gcatgacttg cacttctagg
    32581 gattggagat aattgttttg ctctccgtca gttttgacag gaatcccgta ctcagacagg
    32641 gcgaggagaa tctggtcatt acgactgcgg ctggaggtca gaagggcaat ttccttaaag
    32701 gcaacacctt tttcttgatg aagtttcaga atctccttga taactaagcg catttcgcct
    32761 gttagtttcg tttctgtttg actctcttct tcctcacctg tatcgtcctt gtcgtagagg
    32821 agaaattcag ccttgttgtc tggattggga gtcagtttgg tattggcaaa aacaagctgg
    32881 tgcatgttat catagttgat ttcgccgacc tcttggtcca tgagacgttc aaagacatca
    32941 ttggttgctg acagcacttc tgaactacta cggaaatttt ccttgaggag aatgagcttg
    33001 ccttcttgag gattttgcgc atagcgttgg aatttctcat tgaaaatctg cgggtctgcc
    33061 tgacggaaac gatagatgga ttgcttgata tctcccacca taaagcgatt gtggccatta
    33121 gacaacaatt ccagcatccg ttcttgaata tggttggtat cctgatactc atcgaccatg
    33181 acttcatgga agcgctcctg ataagactca cgaacttgtg ggaaattttc taaaatctca
    33241 atggtgtaat ggctgatatc agcgaattca aaggcatttt cctgtcgttt tctctgacga
    33301 taagcctcta caaaatcgct catgaaagat tggaaggttt tagctagttt ccaagtgtct
    33361 ccatgataac gttcttgata gtcgagaatc gctatctggt ctgataattg tcctagttta
    33421 gtaaactggg tctttctctc ttcgttgtag gcatcagcca ggggcttcaa atcagcctta
    33481 cggctggcat tagtcagagc acgaccgttt ttctccttag agatggcgac aacacgcgca
    33541 agtactgcct gataagcctg actatcgaac tcctgattta gggagccaat ttcatccaga
    33601 attaactgaa cattttctaa ataggcagcc tttgcaaact ccttggcatc gttatccaga
    33661 tggtaacgga aaaagctttc caaatcccag agggcttgtt tgatttgctc agtcagtttt
    33721 tctttttcac tggtaaaatc agctttctca aagcctttga ggaaagattc actcagccac
    33781 ttttgaggat tactggtgga ttggaggaag tcatagattt tatagacttg ctggcgcaga
    33841 ccccgttcgt ccttgccacg cccagcaaag tttttcagca aatgactaaa gctctctttc
    33901 tgtttacctt ggtaatgcgc ttcaaagacc tcatgaaaga cttcgttttc gagaagaagt
    33961 tgctcgcttt ggttttgtaa aatacggaaa ttaggtgcaa tatcaagcag ataaccatgt
    34021 ttgccaagga atttttgtgt gaaagagtcc atggttccga tggcagcgtt gggtaggtct
    34081 gccaactggc aacccaagtg ttgtttgaga tcgacatcat ctgtttcttg gattttcttg
    34141 ctgatttttt tctctaaacg ttctttaagt tcagttgcag ccttgacggt aaaggttgag
    34201 ataaagagtt gagaaatttc gacaccacgc gccaattggt ccagaatgcg ctctaccatg
    34261 acaaaggtct ttccagaacc agccgatgct gagaccagga tattctgacc agaagtgtag
    34321 atagcttcga tttgttcggc agttttcttc tgttccttgc tcgaatttgc ttctgcttct
    34381 tgcagttttt gaatctcctc ctcacttaaa aagggaataa gcttcatcga tttaactcct
    34441 ctcttatttt ttcaaaccaa gcttgcttga gtttttctcc gaccagacgc ttgccatcag
    34501 ctaggtccaa cttttctagg aaacgggctt ggcccagatg gtaattggct tcaaagcctg
    34561 taatagcctg atgttgctgg acgtatgggg caatgcttct gccattttca gtataaggat
    34621 tgatggcgaa ccggcctgct aaaatcttct cagcagcttt cttgtaaaga taggcattgt
    34681 agtccagtag gagctgaaat tcctcatctg tcagttgatt agccttgttt ttgttataaa
    34741 gttcgcctaa ataactgctt tctttttcca agaagagccc ttggtatttc atagatttgc
    34801 tggcttctac cactgctcct gccagacttt ttaccgccat cagagattgg acaggttcag
    34861 ccatttccaa gtacatggcg ccgaaaaagt tctgctcccc ttctcttttt agggcagcaa
    34921 gataggttgg taactgagaa ttgagcccat taaagaaatg aggaaactgg aactgagtca
    34981 gactggattt gtagtctact actcctatcg ctccattagc tttcaaacgg tcaatccggt
    35041 ccaccttgcc tcgtacaaag acactgcgtc cattgtctaa ttgaataaag gcttggtctt
    35101 ttccaccaaa atttgcttct tctttgatgg tttcgatggc tggattgtgt cggagaatat
    35161 gtccagtcgt ccgtgcaaca tcaagcaaaa cttccttggt aaactgggct tccaaacttt
    35221 cttgataaat agcttcaaat tcgcgttctt gactggtttc ttgaatagct tgttctagac
    35281 gttggtcaaa ggaatcttca ttaggcaact gtaaggcgcg ttcaaagata cgatgcaaga
    35341 aattcccgtg actacgggca tcaggatgca aacgtaattc ctcctgcaag cctaaaacgt
    35401 agcgtaggaa ataactgtat tcattgcgat aaaactctgt caaacccgac gtagacaggt
    35461 aaaactcctg tttggcagga tagagagctt gcaaggtgtc cttggctaag gtcttgctgc
    35521 ttggactggt tgggatagct ggattttcca gaccttgctg atctagtttt ttacctatga
    35581 cacgcgacag aaccttgaca aaagtcaaat cttgctcagt atcgctcatc tcaccctgct
    35641 ggtgataggc aaccagacta gacaaaagac tgtgatagga ccccatatcc tccttagaca
    35701 gtcctttgtg attcatcctc ttctctctcc gcctaaatcc aaaatggatc aactcttgaa
    35761 gataggcaga ttccttactt tcactttcgt taaaaaggct tggagccgac aagaacaact
    35821 gcttacgagc agaattgacc aaggaaagca tagtgtagcg atttttcttg agattttcac
    35881 tgctggcaat cagtaattga acgccttctt cggtcgtttg gtttaggttt ttcctttctt
    35941 catctgtcag aagactggtg ttttgagaaa tttttggtaa attgtcctga gttagtccaa
    36001 tagcatagac aaagtcagca gtcaatggtg caatcaaatc gtaactctgc accagaacag
    36061 tgtccactgt tgctggaatg gtacggtatt gggacaaact cattccagaa tggagcaagg
    36121 ctaggaagtc ttccagacta acctgtgaac cagcaaaaac agtcgcaaat tgttctaaaa
    36181 catggcaaaa agccttccaa acttcggctt gtctttcctg ttctacagct tccaaagtgg
    36241 ttgtcaaatc ttgtaactgc ttggtcacag ctccttcttt tagaaagaca ctccattttt
    36301 gtaggaggtt ttcagccttt tgttttcggc tggcaaagag ggtttcaaga ggtgctaaaa
    36361 ttctcaggcg gaggacattc aaacgctcaa gattaaattt tccatggtgg gatttggtga
    36421 aggtttgctg aaaggctggc aagccattaa taccaagata gcggatatat tgttcaaaag
    36481 catcaatatc agactgactg aggtcaatat acaagtcagt tctaagaaga ttaatcaaat
    36541 cctcctgacg aaaacggtaa cgttttaaag ctaaaataga ctcgacaaac tgagtcaagg
    36601 gatgatgagc catggcttcg cttctaccaa gataaaaagg aatctgatac tggtcaaaaa
    36661 tggttttgag agataactgg taagaagcta catcccccaa gagaatacga aaatgcttgt
    36721 agctcaggtc tgagttctca tgtaatttct gacgaatgct acgggctact agctccaact
    36781 cctccttttg cgtcaaacaa gaccagattt gtaaattttc acggtctttc tcatcgacat
    36841 ccaaagcgag ttctgaaaag tcataagaag actccaacaa acgagaggcc ttgtcaaaac
    36901 tatccatctt ctcatgagtt tgagaacagt cctgagcggg cgtttggtat ttagaagcca
    36961 gatgatggag aaattttacg ctggcttggt agagattgcc ctcgctaaaa ggactggtat
    37021 aggctttctt actagcataa gccccgataa caatctcagc acctttgccg tgaagtaagt
    37081 ccacaacccg ctcttcctca gcagaaaaac gagtaaagcc gtcaatgacc aaggcgattt
    37141 gattaaaatc actacttacc ttgtcattct caatagcctc aatcaaatgg gacaactgac
    37201 ttccctgggc taactgccct tgattaagat aggctgttac tttctcaaaa atcaagagta
    37261 aatccgccct cttatcctca tctgttaaat tctccaagtc caaaaaattc atctgagatt
    37321 tggtcatctc atggtaaagc tcaattaact gctggatcaa ttgaggatcc tgcttaatag
    37381 cgccataaac acgcaagtcc ttgggatcga gttcggcaag gcatttgtaa aaggccaacc
    37441 caagaccgat atcatcaaga gtagttttag ctggtaaatc attcaagacc agataacgag
    37501 ccatttgagc aaagcgcgtg acggtaatcg aaaaagaagc ctgctgggac aagcattcca
    37561 gcacggcgcg ttccttttca aaagaaagag agttgggggc aatgtagaag acccgcttgc
    37621 cagctgcaac tagctcttct gcctctcttg ttagaatttc tgtcaaagaa gttcgaatat
    37681 cagtataaag taatttcatc tcagcctcgt tggaattttt catcacccta tattatacca
    37741 tgattagcct cgtaaatctg ttaaaatatt taggccatcc tttcttttct tcatcatctg
    37801 ctaaatctta aatacttagc tttacttgta ttagatagaa taagtctggc tactgaaaat
    37861 cacataataa aaaagcctcg gtaacaaggc tttgagtttt atgattgttt cttaggtacg
    37921 gaatacactt caatgtgttg tcccagtatc ttaatgtcga cgggtagatt gtctgattta
    37981 tcgccatcaa catcggactc taattcgata tcagaagaag ttttaatatt acgtgccttt
    38041 atatattcaa tattcttgat agaatgattg aactatagta aattgaaact ataatagtac
    38101 accgtggatg ctaaaatatt tctagaaatt aatttgattt ccctaatcaa gctgttcgta
    38161 tcttatttca atcta
//
LOCUS       DAYYYC010000017        36599 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.017, whole genome shotgun sequence.
ACCESSION   DAYYYC010000017 DAYYYC010000000
VERSION     DAYYYC010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36599
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.017"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..752
                     /gene="cozE"
                     /locus_tag="ACHBV5_000891"
     CDS             <1..752
                     /gene="cozE"
                     /locus_tag="ACHBV5_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HFM9966717.1"
                     /translation="LSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGSVLSA
                     LISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIARYISG
                     VSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANIFTDP
                     HRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMIVAVP
                     TYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            1286..1633
                     /gene="ssrA"
                     /locus_tag="ACHBV5_000892"
     tmRNA           1286..1633
                     /gene="ssrA"
                     /locus_tag="ACHBV5_000892"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1806..1893)
                     /locus_tag="ACHBV5_000893"
     tRNA            complement(1806..1893)
                     /locus_tag="ACHBV5_000893"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1857..1859),aa:Ser,seq:gga)
     gene            2056..2796
                     /locus_tag="ACHBV5_000894"
     CDS             2056..2796
                     /locus_tag="ACHBV5_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFM9966718.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            2793..3704
                     /gene="pfkB"
                     /locus_tag="ACHBV5_000895"
     CDS             2793..3704
                     /gene="pfkB"
                     /locus_tag="ACHBV5_000895"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFM9966719.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTVEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            3701..5653
                     /locus_tag="ACHBV5_000896"
     CDS             3701..5653
                     /locus_tag="ACHBV5_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFM9966720.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSAGQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            5790..8042
                     /locus_tag="ACHBV5_000897"
     CDS             5790..8042
                     /locus_tag="ACHBV5_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFM9966721.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKTLLDLPP
                     VDMETGEILTEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAK
                     EALEYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(8087..8515)
                     /locus_tag="ACHBV5_000898"
     CDS             complement(8087..8515)
                     /locus_tag="ACHBV5_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HFM9966722.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITAGITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            8653..9795
                     /locus_tag="ACHBV5_000899"
     CDS             8653..9795
                     /locus_tag="ACHBV5_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFM9966723.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            9804..11018
                     /gene="thiI"
                     /locus_tag="ACHBV5_000900"
     CDS             9804..11018
                     /gene="thiI"
                     /locus_tag="ACHBV5_000900"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFM9966724.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMIFKISSKRSDHTFELDSRELNQTLGRAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            11153..11976
                     /locus_tag="ACHBV5_000901"
                     /pseudo
     CDS             11153..11976
                     /locus_tag="ACHBV5_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            11998..12737
                     /locus_tag="ACHBV5_000902"
                     /pseudo
     CDS             11998..12737
                     /locus_tag="ACHBV5_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            12750..13916
                     /locus_tag="ACHBV5_000903"
     CDS             12750..13916
                     /locus_tag="ACHBV5_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HFM9966725.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     ATTFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            14424..15917
                     /locus_tag="ACHBV5_000904"
     CDS             14424..15917
                     /locus_tag="ACHBV5_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HFM9966726.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            15930..16994
                     /locus_tag="ACHBV5_000905"
     CDS             15930..16994
                     /locus_tag="ACHBV5_000905"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFM9966727.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     FQLDELNLLVKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSSGKFLDKHDRVFEGYPAY
                     GGNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWISDNAIYIKEFKNSDFNLV
                     FLLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQNEFADFVALVDKSQLAI
                     QKSLEELETLKKSLMQEYFG"
     gene            17054..17290
                     /locus_tag="ACHBV5_000906"
     CDS             17054..17290
                     /locus_tag="ACHBV5_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFM9966728.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            17287..17700
                     /locus_tag="ACHBV5_000907"
     CDS             17287..17700
                     /locus_tag="ACHBV5_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFM9966729.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            17818..18783
                     /gene="xerA"
                     /locus_tag="ACHBV5_000908"
     CDS             17818..18783
                     /gene="xerA"
                     /locus_tag="ACHBV5_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008907 - integrase activity [Evidence
                     IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase/integron
                     integrase"
                     /protein_id="HFM9966730.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            18768..19390
                     /locus_tag="ACHBV5_000909"
                     /pseudo
     CDS             18768..19390
                     /locus_tag="ACHBV5_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            19420..22770
                     /locus_tag="ACHBV5_000910"
     CDS             19420..22770
                     /locus_tag="ACHBV5_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFM9966731.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFGENCCVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIEEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            23041..23241
                     /locus_tag="ACHBV5_000911"
     CDS             23041..23241
                     /locus_tag="ACHBV5_000911"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966732.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVADKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATLTRIEEIFEEYKSS"
     gene            complement(23356..23826)
                     /locus_tag="ACHBV5_000912"
     CDS             complement(23356..23826)
                     /locus_tag="ACHBV5_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFM9966733.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(23843..26116)
                     /locus_tag="ACHBV5_000913"
     CDS             complement(23843..26116)
                     /locus_tag="ACHBV5_000913"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HFM9966734.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHINKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            26463..29564
                     /locus_tag="ACHBV5_000914"
     CDS             26463..29564
                     /locus_tag="ACHBV5_000914"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFM9966735.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQKSEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQVDD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHDSDQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            29646..30653
                     /gene="pfkA"
                     /locus_tag="ACHBV5_000915"
     CDS             29646..30653
                     /gene="pfkA"
                     /locus_tag="ACHBV5_000915"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFM9966736.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     L"
     gene            30712..32217
                     /gene="pyk"
                     /locus_tag="ACHBV5_000916"
     CDS             30712..32217
                     /gene="pyk"
                     /locus_tag="ACHBV5_000916"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFM9966737.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(32961..33176)
                     /locus_tag="ACHBV5_000917"
     CDS             complement(32961..33176)
                     /locus_tag="ACHBV5_000917"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HFM9966738.1"
                     /translation="MEPKIRNSDYLFIKNTPQIDYNTIGIFQVDGTNYVKKLRQGYLK
                     KTQSRILRHPPRRKQPYSYHRESCQAI"
     gene            34024..34896
                     /locus_tag="ACHBV5_000918"
     CDS             34024..34896
                     /locus_tag="ACHBV5_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HFM9966739.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            34909..35073
                     /locus_tag="ACHBV5_000919"
     CDS             34909..35073
                     /locus_tag="ACHBV5_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966740.1"
                     /translation="MTVILGFLFLFLMTWWVISIVNSQKPLKNETFIGYVQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(35042..35386)
                     /locus_tag="ACHBV5_000920"
                     /pseudo
     CDS             complement(35042..35386)
                     /locus_tag="ACHBV5_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            35529..35840
                     /locus_tag="ACHBV5_000921"
     CDS             35529..35840
                     /locus_tag="ACHBV5_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966741.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            35844..36560
                     /locus_tag="ACHBV5_000922"
     CDS             35844..36560
                     /locus_tag="ACHBV5_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFM9966742.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFNTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
BASE COUNT        11333 a         6400 c         7849 g        11017 t
ORIGIN      
        1 acttatctaa ttatcctgcg ctccagaatt tggatgtaga agctacaatt cagcagttaa
       61 acttatccta tgttgatatt cttcaaaata tcctaaatag cgtatcaaat agtgtgggga
      121 gcgtcttgtc agctcttatc agtactgttt tgattttgat tatgactcca gtttttttgg
      181 tttatttctt attagatgga cataaattct tgcccatgct tgaaagaacg attctaaaga
      241 gggatcgctt gcatattgca ggcttattaa agaatttaaa tgcgacgatt gctcgctata
      301 ttagtggagt ttcgattgac gcaatcatta taggttgttt ggcttatatt ggctatagta
      361 ttattggttt aaaatatgct ttagtttttg ccattttttc tggtgtagcc aatttaattc
      421 cttatgtggg gccaagtatt ggtttgattc ctatgatcat cgcaaatata ttcactgatc
      481 cccatagact gctgattgca gtgatttata tgcttgttgt tcagcaggta gatggcaata
      541 tcttatatcc tcgaatcgta ggaagtgtta tgaaggttca tccaatcacg attttagttt
      601 tacttttgtt gtcaagcaat atctatggtg tagttggaat gattgtcgca gtgccaacct
      661 attctatctt gaaagaaatt tctaagttct tatcccgttt gtatgaaaat cataaaataa
      721 tgaaagaacg agaaagagaa ttagctaagt aaaagtcagg agaaccctga tttttcttta
      781 ctggaagtgg cctttagatt agaagactga aaataagtta aagtcttaaa ctaattttca
      841 cagctaagaa tagtagaagt taatctgata aaaatcgaaa aaaccagtgg aattctgtgt
      901 cagggtaagt tccactggtt ttcatagtct attaaagttc gaatgaaacc tatttatagt
      961 agattgaaac tagaatagta cacctctaat tctaaaacat tgttagaaat cgatttgact
     1021 gtcctgatct attcgtccta ttcttatttc attttactat attttggtgc aataagtgaa
     1081 aagtagaccg aataatataa ggattgattt tatagttttt aaactcaaat gaattgaaat
     1141 aaagagagta cgaaaattct catctgaaag tattttagaa taattctctt cgtgaatttc
     1201 ttcaaaacag atagcttcat cttaggtatg tgatttcttt ttgcattttt gagttagata
     1261 aggtataatg gttttattgt cttttggggt cgttacggat tcgacaggca ttatgaggca
     1321 tattttgcga ctcgtgtggc gacgtaaacg ctcagttaaa tataactgca aaaaataaca
     1381 cttcttacgc tctagctgcc taaaaaccag caggcgtgac ccgatttgga ttgctcgtgt
     1441 tcaatgacag gtcttattat tagcgagata cgattaagcc ttgtctagcg gtttgataag
     1501 agattgatag actcgcagtt tctagacttg agttatgtgt cgaggggctg ttaaaataat
     1561 acataaccta tggttgtaga caaatatgtt ggcaggtgtt tggacgtggg ttcgactccc
     1621 accggctcca ttattccttt gcattccttg gtaaaacgtt gttaaatcaa cgttttttat
     1681 ttttatcttt ggtattcctt tgcattcttt tgctaaaaag ggagtcacaa acagacccta
     1741 ttttaaaaaa aggatagaaa aaaggataca acatttgtcg catcctaaaa ataatctttt
     1801 ttcgacggaa gacatgggat tcgaacccac gcacgctatt acacgcctac cgcgtttcca
     1861 acacggcctc ttaagcctct tgagtaatct tccaatactt actcaaatag tctaccataa
     1921 aggctcttat cttgcaataa aaattctaga aataagaaaa aatgatagat tttgaaagaa
     1981 aatgataaaa aatgcttgac ttcgaaagaa agtatgatag aatgaatagt gtaaacgata
     2041 acaggaggtg attcagtgtt aaaaacagaa cgtaaacaac taattttaga ggagttaaat
     2101 cagcatcatg tagtttctct agaaaaatta gttagtttgc tagaaacgtc agaatcaacg
     2161 gttcgaagag acttggatga gttggaagcg gaaaacaagc ttcgtcgtgt gcatggtgga
     2221 gcagaactcc cccactcctt acaggaagaa gaaaccattc aagaaaaatc tgtcaaaaac
     2281 cttcaagaaa agaagttgct ggctcagaaa gcagcctctc tcattaaaga aaaagatgtc
     2341 atctttatcg atgctggaac aacaactgct tttttgattc atgaattggt caataagaat
     2401 gttacagttg tgaccaactc cattcaccat gccgctcagt tggttgaaaa gcagattcca
     2461 actgtcatgg ttggaggaaa cgtcaagacg gcgacagatg ctagtatcgg gggcgttgct
     2521 cttaaccaga ttaaccaatt gcactttgac cgtgccttta tcggaatgaa tggtgttgac
     2581 gatggctatt atacgactcc tgatatggag gagggagctg tgaaaagagc tattttggag
     2641 aatgccaagc agacctacgt cttggtggat tcgtcaaaaa ttggacaaac ttgctttgcc
     2701 aaggtagcac cactcaaacg cgctatcgtt atcactagtc aagggcatga gctcttgcag
     2761 gttattaagg agaaaacgga ggtaatagaa gtatgattta tacagtcaca ctcaatccat
     2821 ccattgacta tatcgttcgt ttggaccaag tcaaagttgg tagtgtcaat cgtatggaca
     2881 gtgatgataa gtttgctggt gggaaaggaa tcaatgtcag ccgtgtcttg aaacgtttga
     2941 atataccaaa tacagcgacg ggatttatcg gtggctttac tggtaaattt atcacagata
     3001 ctctagcaga ggaagaaatc gagacacgtt ttgtccaagt ggcagaagat actcgtatca
     3061 atgttaaaat caaagcagac caagaaacag aaatcaacgg aacgggtcca actgttgaac
     3121 cggttcagct agaagaattg aaagctattt tatctagtct gacagtagaa gatacagttg
     3181 tctttgcagg ttcaagtgct aaaaatctag gcaatgttat ctataaggat ttgatttcct
     3241 tgacgcgcca gactggtgcg caagtggtct gtgactttga aggacagacc ttaattgata
     3301 gtttggacta ccagcctctt cttgtaaaac caaacaatca tgaacttgga gcgatttttg
     3361 gggttaaact cgaaagttta gatgaaattg agaaatacgc tcgtgagtta ctggctaagg
     3421 gtgctcaaaa tgttattatc tctatggctg gtgatggcgc ccttcttgtc acatctgagg
     3481 gagcttactt cgctaaacca atcaaaggaa cagtcaaaaa ttcagttgga gctggtgatt
     3541 ctatggttgc tggattcaca ggtgaatttg tcaaatcaaa agacgcagta gaagccttca
     3601 aatggggagt ggcttgcgga acggcaacta ccttctcaga tgacttggca acggcggaat
     3661 ttattaaaga aacatatgga aaagttgagg tagaaaaaag atgaaaattc aagacctatt
     3721 gagaaaagat gtcatgttgc tagatttgca ggcaactgaa aaaacagctg tcatcgacga
     3781 gatgattaaa aatttgacag agcacggtta tgtaacagat tttgaaacat ttaaagaagg
     3841 aattttggcg cgtgaagctt tgacttctac tggtttgggt gatggaatcg caatgcctca
     3901 cagcaaaaac gctgctgtca aagaagcgac agttctattt gctaagtcaa acaagggtgt
     3961 tgactacgag agcttggatg gacaagcaac tgacctcttc ttcatgattg cagctccaga
     4021 aggtgccaat gatactcact tggcagcctt ggcagaattg tctcaatact tgatgaaaga
     4081 cggttttgca gacaaacttc gtcaagcaac atctgcaggc caagttatcg aactttttga
     4141 ccaagcttca gaaaaaactg aggaacttgt tcaagcacct gctaatgact ctggtgactt
     4201 tatcgtagct gttacagctt gtacaacagg tattgcccac acttacatgg cccaagaagc
     4261 ccttcaaaaa gtagctgctg aaatgggggt tggtatcaag gtcgaaacca acggtgctag
     4321 cggtgttgga aatcaactaa ctgcagaaga tatccgtaag gctaaagcta ttatcattgc
     4381 agcagacaag gccgttgaaa tggatcgatt tgatggaaaa ccattgatca atcgtccagt
     4441 tgctgacggt atccgtaaga cagaagagct aattaacttg gctctttcag gagatactga
     4501 agtctaccgt gccgctaatg gtgccaaagc tgcaacagcc tctaacgaaa aacaaagcct
     4561 tggtggtgcc ttgtacaaac acttgatgag tggtgtatct caaatgttac cattcgttat
     4621 cggtggtggt atcatgattg cccttgcctt cttgattgac ggtgctttgg gtgttccaaa
     4681 tgaaaacctt ggcaatcttg gttcttacca tgagttagct tctatgttta tgaaaattgg
     4741 tggagctgcc tttggtttga tgcttccagt ctttgcgggt tatgttgcct actctattgc
     4801 tgaaaaaccg ggtttggtag caggtttcgt ggctggtgct attgccaaag aaggttttgc
     4861 ctttggtaaa attccttatg ccgcaggtgg tgaagcaact tcaactcttg caggtgtctc
     4921 atctggtttc ctaggtgccc ttgttggtgg atttatcgca ggtgccttgg ttcttgccat
     4981 caagaaatac gttaaagttc ctcgttcact cgaaggtgct aaatcaatcc ttctattgcc
     5041 acttcttgga acaatcttga caggatttgt tatgctagct gtgaatatcc caatggctgc
     5101 aatcaacact gctatgaatg acttcctagg cggtcttgga ggaggttcag ctgtccttct
     5161 tggtatcgtc cttggtggaa tgatggctgt tgacatgggt ggaccagtta ataaagcagc
     5221 ttatgtcttt ggtacaggta cgcttgcagc aactgtttct tcaggtggtt ctgtagccat
     5281 ggcagcagtt atggctggag gaatggtgcc accacttgca atctttgtcg caactcttct
     5341 tttcaaagat aaatttacta aggaagaacg taactctggt ttgacaaaca tcatcatggg
     5401 cttgtcattt atcactgagg gagcgattcc atttggtgcc gctgacccag ctcgtgcgat
     5461 tccaagcttc atccttggtt cagcagtagc aggtggactc gttggtctta ctggtatcaa
     5521 actcatggcg ccacacggag gaatcttcgt tatcgccctt acttcaaatg ctctccttta
     5581 cctcgtttct gtcttggtag gagcaatcgt aagtggtgtg gtttatggtt acctacgcaa
     5641 accacaagca taaaaaatag aaaaatgaaa agattggacc gtttggtgca gtctttttct
     5701 cttcccgaaa tgcctgtgaa atatggtata atagaagaat ggcaaacaag aatacaagta
     5761 caacaagacg gagaccgtct aaagcagaac tggaaagaaa agaagcgatt caacgaatgt
     5821 tgatttcgtt aggaattgcg attttattga ttttcgcagc cttcaaatta ggggctgcag
     5881 gtataaccct ttataattta attcgcttgc tagtgggtag cctagcttat ctggcgatat
     5941 tcggcctatt aatctatctc ttctttttca agtggatacg aaaacaggaa ggactcttat
     6001 ctggcttttt caccatattt gctggcttac tcttgatttt tgaggcctac ttggtttgga
     6061 aatatggttt ggacaagtcc gttctaaaag ggaccatggc tcaggttgtg acagatctga
     6121 ctggttttcg aacgactagc tttgctggag ggggcttgat cggggtcgct ctttatattc
     6181 caacagcctt tctcttttca aatatcggaa cttactttat tggttctatc ttgattttag
     6241 tgggttctct cctagtcagc ccttggtctg tttacgatat tgctgaattt ttcagtagag
     6301 gctttgccaa atggtgggaa gggcacgagc gtcgaaaaga ggaacgcttt gtcaaacaag
     6361 aagaaaaagc tcgccaaaag gctgagaaag aggctagatt agaacaagaa gagactgaaa
     6421 aaaccttact cgatttgcct cctgttgata tggaaacggg tgaaattctg acagaggaag
     6481 ctgttcaaaa tcttccacct attccagaag aaaagtgggt ggaaccagaa atcatcctgc
     6541 ctcaagctga acttaaattc cctgaacagg aagatgactc agatgacgaa gatgttcagg
     6601 tcgatttttc agccaaagaa gcccttgaat acaaacttcc aagcttacaa ctctttgcac
     6661 cagataaacc aaaagatcaa tctaaagaga agaaaattgt cagagaaaat atcaaaatct
     6721 tagaagcaac ctttgctagc tttggtatta aggtaacagt tgaacgggcc gaaattgggc
     6781 catcagtgac caagtatgaa gtcaagccgg ctgttggtgt aagggtcaac cgcatttcca
     6841 atctatcaga tgacctcgct ctagccttgg ctgccaaaga tgtccggatt gaagcaccaa
     6901 tccctgggaa atccctaatc ggaattgaag tgcccaactc cgatattgcc actgtatctt
     6961 tccgagaact atgggaacaa tcgcaaacga aagcagaaaa tttcttggaa attcctttag
     7021 ggaaggctgt taatggaacc gcaagagctt ttgacctttc taaaatgccc cacttgctag
     7081 ttgcaggttc aacgggttca gggaagtcag tagcagttaa cggcattatt gctagcattc
     7141 tcatgaaggc gagaccagat caagttaaat ttatgatggt cgatcccaag atggttgagt
     7201 tatctgttta caatgatatt ccccacctct tgattccagt cgtgaccaat ccacgtaaag
     7261 ccagcaaggc tctgcaaaag gttgtggatg aaatggaaaa ccgttatgaa ctctttgcca
     7321 aggtgggagt tcggaatatt gcaggtttta atgccaaggt agaagagttc aattcccagt
     7381 ctgagtacaa gcaaattccg ctaccattca ttgtcgtgat tgtggatgag ttggctgacc
     7441 tcatgatggt ggccagcaag gaagtggaag atgctatcat ccgtcttggg cagaaggcgc
     7501 gtgctgcagg tatccacatg attcttgcaa ctcagcgtcc atctgttgat gtcatctctg
     7561 gtttgattaa ggccaatgtt ccatctcgtg tagcatttgc ggtttcatca ggaacagact
     7621 cccgtacgat tttggatgaa aatggagcag aaaaacttct tggtcgagga gacatgctct
     7681 ttaaaccgat tgatgaaaat catccagttc gtctccaagg ctcctttatc tcggatgacg
     7741 atgttgagcg cattgtgaac ttcatcaagg ctcaggcaga tgcagactac gatgagagtt
     7801 ttgatccagg tgaggtttct gaaaatgaag gagaattttc ggatggagat gctggtggtg
     7861 atccgctttt tgaagaagct aagtctttgg ttatcgaaac acagaaagcc agtgcgtcta
     7921 tgattcagcg tcgtttatca gttggattta accgtgcgac ccgtctcatg gaagaactgg
     7981 agatagcagg tgtcatcggt ccagctgaag gtaccaaacc tcgaaaagtg ttacaacaat
     8041 aaaaaaatag cttctttccg agtttggagg gaagctattt tagtggctat tgattgcttt
     8101 tattttctga agttggcgca ttggactgtt tttcgttttc agtagcaggt ttacttgaag
     8161 caggagtaga agagtcctga gttgctgttt tctgatcttc ttttttctct tccttgacgc
     8221 tagattttgg tgtttcctct tgctgtgttt tttcttgact agtgttagtc tctttagttg
     8281 gactggtgtt ttccttaggg gattcctttt ggatttcttt gacaatggtt gtcgtctggc
     8341 ttgtcgtagg ttctttttta atatttttgt tattatccaa ggcgttcatg atcgtgatac
     8401 ccgcggtaat caagccaagg atactagcga ttgtagcaac ggttttttga aagactgtaa
     8461 agcctttttt gatgtgttct gtttttggtt ttgaagttct acgatagtta gacatacatt
     8521 ctctcctttg attatgattt attatactct gtttctttaa aaaaatctta aaaaaagaga
     8581 aattgccctt tcttgtcgca ggctccgttt catgatacaa tagaaggagt gattttagaa
     8641 agcgtgagaa acatgattta ctttgataat tcggcgacga ccaggcccta tccagaagcc
     8701 cttgaaacct atatgcaggt ggcttcaaaa attttaggaa atccatctag tctccatcgt
     8761 ttgggagacc aggcaacacg aattttagat gcttcccgtc aacagattgc agatttaatc
     8821 ggtaagaaaa gtgatgaaat cttctttaca tctggtggga cagaagggga taactggatc
     8881 atcaagggag tagcatttga aaaagcccag tttggcaagc acatcatcgt atcagccatt
     8941 gaacatccag cagttaagga atcagccctc tggttgaaag ctcaaggttt tgaagtggat
     9001 tttgctccag ttgataacaa aggatttgtg gatgttgagg cgctagaaga tttgataaga
     9061 cctgatacga ccctcgtttc catcatggca gttaacaatg aaattggctc tgttcagccc
     9121 attgaggcta tttcaaaact attggcagac aagccaacta tttccttcca cgttgatgcg
     9181 gttcaggcgc ttgccaagat tccgactgaa aagtatctga cagaacgagt ggatttcgcg
     9241 actttctctg gtcacaagtt ccacggaatc cgtggtgttg gttttatcta tatcaagtct
     9301 ggcaagaaga ttacgcctct tttaacaggt ggtggtcagg aacgtgatta ccgttcgaca
     9361 actgaaaatg tggcaggaat tgcagcgacc gctaaggctc tccgtttatc tatggaaaag
     9421 ctagatatct ttaggagcaa gactgggcag atgaaggcag tgattcgtca agcacttctg
     9481 gactatccgg atatatttgt cttttcagat gaggaagact tcgcccctca tattctgact
     9541 tttggaatca agggtgttcg tggtgaggtc attgttcacg cctttgaaga ctatgatatt
     9601 ttcatctcaa cgacctcggc ttgttcgtcc aaggctggga aaccagccgg aaccctgatt
     9661 gctatgggag tggacaagga taaggctcag tcagctgtgc gtcttagtct agaccttgaa
     9721 aatgatatga gtcaggtcga gcagttcttg accaagctaa aattaattta caatcaaact
     9781 agaaaagtaa gataggagca ttcatgcagt attcagaaat tatgattcgc tacggtgagc
     9841 tgtcaaccaa gggcaaaaat cgtatgcgtt tcatcaataa acttcgcaat aatatttcag
     9901 acgttttgtc tatctatccc caagttaagg taacagcaga tcgcgaccgt gcccacgctt
     9961 acctcaatgg agcagattac acagcagtag cagaatcgct caaacaagta tttggaattc
    10021 aaaacttttc ccctgtttat aaggttgaaa aatctgtaga agttctgaag tctgctgtcc
    10081 aagagattat gcaggacatc tacaaggaag gcatgatctt taaaatctct agcaagcgta
    10141 gcgaccacac ctttgaattg gacagtcgtg aactcaacca aacgcttgga agggctgtat
    10201 tcgaagccat tccaaacgta caagctcaaa tgaaaagtcc tgacatcaat cttcaggtgg
    10261 agatacgtga agaagcagcc tatctttctt atgaaaccgt tcgaggggca ggtggattac
    10321 cagtgggaac ttctggtaag ggcatgctca tgttgtcagg gggaatcgat tcccctgtag
    10381 ctggctatct agcgcttaaa cgaggggtag atatagaggc agttcacttt gccagcccac
    10441 cttacacgag tcctggtgct cttaaaaaag cccaagattt gacccgtaaa ttaaccaaat
    10501 ttgggggaaa tatccagttt atcgaagttc cttttacaga gattcaagag gaaatcaaag
    10561 ccaaagcgcc agaagcctac cttatgacct tgacgcgtcg ttttatgatg cgtattactg
    10621 accgtattcg tgaggtacga aatggtttag ttatcatcaa tggggaaagt ctaggtcaag
    10681 tagccagcca aacccttgaa agtatgaagg ctatcaatgc tgttaccaac actcccatca
    10741 ttcgtcctgt ggttaccatg gacaagttgg aaatcattga catcgcccag gaaatcgata
    10801 cctttgacat ttcaatccaa ccgtttgaag actgttgtac catttttgca ccagatcgtc
    10861 caaaaacaaa tcctaaaatt aagaatgcgg agcagtacga agcgcgtatg gatgttgaag
    10921 gcttggttga gcgagcagtg gctggaatca tgattactga aatcacacct caagccgaaa
    10981 aagatgaagt tgatgacttg attgacaatc tgctctaatt cagaaaatcc aaaagaatag
    11041 cgaaaatcag taaaaaaagt tagttttttc tctaaaaaca ggtaaaaaac taactttttt
    11101 tatttttatg atataatgat ataaaatttt gaatatagag agttttctgg caatgaatca
    11161 atcctacttt tatctaaaaa tgaaagaaca caaactcaag gttccttata caggtaagga
    11221 gcgccgtgta cgtattcttc ttcctaaaga ttatgagaaa gatacagacc gttcctatcc
    11281 tgttgtatac tttcatgacg ggcaaaatgt ttttaatagc aaagagtctt tcattggaca
    11341 ttcatggaag attatcccag ctatcaaacg aaatccggat atcagtcgca tgattgtcgt
    11401 tgctattgac aatgatggta tggggcggat gaatgagtat gcggcttgga agttccaaga
    11461 atctcctatc ccagagcagc agtttggtgg taagggtgtg gagtatgctg agtttgtcat
    11521 ggaggtggtc aagcctttta tcgatgagac ctatcgtaca aaagcagact gccagcatac
    11581 ggctatgatt ggttcctcac taggaggcaa tatacccagt ttatcggttt ggaataccaa
    11641 gaccaaattg gttgcttggg cgttttttca tctgcaaact ggctccacca agaagccttt
    11701 aaccgctata tcgagtgcca gaaactatcg cctgaccagc gcatcttcat ctatgtagga
    11761 acagaagaag cagatgatac agacaagacc ttgatggatg gcaatatcaa acaagcctat
    11821 atcgactcgt cgctttgcta ttaccatgat ttgatagcag ggggagtaca tctggataat
    11881 cttgtgctaa aagttcagtc tggtgccatc catagtgaaa tcccttggtc agaaaatcta
    11941 ccagattgtc tgagattttt tgcagaaaaa tggtaagtta agaaaggaaa aaacgaaatg
    12001 catattgaac atcttagcca ctggagtggt catcttaacc gtgaaatgta ccttaaccgt
    12061 tatggacatg gtgggattcc agttgtggtc tttgcttcat caggtggtag tcacaacgaa
    12121 tactatgatt ttggcatgat tgatgcctgt gcttccttta tcgaggaagg ccttgtccag
    12181 ttctttaccc tatctagttt ggatagtgag agctggttgg ttacttggaa aaatgctcat
    12241 gaccaagcgg aaatgcaccg tgcctacgaa tgttatgtga ttgaggaggc cattctttta
    12301 tcaagcacaa gacaggttgg tttgatggca tgatgacgac aggttgctct atgggagcct
    12361 atcatgcact caatttcttc ctccagcatc cagatgtctt taccaaagtg attgctctca
    12421 gtggtgttta cgacgcacgt ttctttgtcg gtgattacta caacgatgat gctatttacc
    12481 aaaactcgcc agtagattat atttggaacc aaaacgacgg ctggtttatt gaccgttacc
    12541 gtcaggcaga gattgtgctg tgtacggggc ttggagcctg ggaacaagat ggtttgccat
    12601 ccttttacaa gctcaaagaa gcctttgaca agaaacaaat tccagcctgg tttgctgaat
    12661 ggggacatga tgtcgcccat gactgggaat ggtggcgtaa acaaatgcct tatttcctcg
    12721 gtaatctcta tttataaaag gagttaccta tgaattacct tgttatttct ccctactatc
    12781 cacaaaactt tcaacagttt accatcgaac tagctaataa aggcatcaca gtcttgggaa
    12841 ttggtcaaga gtcttacgag caattggatg agcccttgcg caatagcttg accgagtatt
    12901 ttcgtgttga taatcttgag aacatagatg aagtcaaacg tgcagttgct tttctctttt
    12961 ataaacatgg tccaattgac cgcatcgagt ctcacaatga atactggctt gagctagacg
    13021 caacactcag agaacaattc aatgtttttg gtgccaaacc agaggatctc aaaaagacga
    13081 aatataagtc tgaaatgaag aaacttttca aaaaagcagg tgttcctgtg gtacctggag
    13141 ctgttatcaa gacggaagca gatgttgatc aagcagtgaa agaaatcggt cttccaatga
    13201 ttgccaaacc tgataatgga gtgggagcag ccacaacctt taaacttgag acagaagacg
    13261 atatcaatca cttcaagcaa gaatgggacc attcaaccct ttatttcttt gaaaaatttg
    13321 tcacttccag cgaaatctgt acctttgacg ggctcgtgga caaggatgga aagattgtct
    13381 tctcaacaac ctttgactac gcctatacac cgcttgacct catgatttat aagatggaca
    13441 attcttatta tgtgctcaag gatatggatc ctaaactgcg caagtatggg gaagcaattg
    13501 tcaaagaatt tggtatgaaa gaacggtttt tccatattga gttcttccgt gagggggacg
    13561 attatattac catcgagtac aataaccgcc ctgcaggtgg ttttaccatt gatgtttata
    13621 actttgctca ttccttggac ctctatcgtg gctatgcagc tattgtcgca ggagaggagt
    13681 tcccggcgtc agactttgaa actcagtatt gtttggctac ttctcgccgt gcaaatgctc
    13741 actatgttta ttcagaagag gatttgcttg ccaaatatag ccagcagttc aaagttaaaa
    13801 aagtcatgcc agctgccttc gcggaacttc aaggagatta cctgtatatg ctgaccactc
    13861 cgagtcgaca agaaatggag cagatgattg cagatttcgg acaacgtcaa gaataagaac
    13921 tatcggatta aggaaattaa ctcccttaat ccttttgttt tgtctgataa aaaataagag
    13981 catcccaaca aggtagctat cataaaactt gttcgataac tatttgaagc aggattaggt
    14041 ggtcagaaat tgaattttaa tatttcaatt gagtcatagt attgtgtttg cgtatcctta
    14101 aatcagctaa aaggatccat gacgacacct atacgatata gttttcaaga taccaaacaa
    14161 gtctattaat actcaatgaa aatcaaagag caaactagga agctagccgc aggtttctca
    14221 aaacactgtt ttgaggttgt ggatagaact gacagagtca gtatcatata cctacggcaa
    14281 ggtgaagctg acgtggtttg aagagatttt cgaagagtat aaaatattca ggtgacgcat
    14341 agatatagtt aattgaagct ttgtttgaaa tctgataaaa taatgatatt actaagtttt
    14401 aaaaactaaa gaaaagggaa gatatgatta caggcgaatt aaaaaataaa atcgatcagc
    14461 tgtgggaaat tctttggaca gaaggaaacg caaatccttt aacaaatatt gaacagttga
    14521 cttatctctt atttatgaaa gatttggata gtgtcgagct tggacgtgaa agtgatgctg
    14581 aatttctagg gattccttat gagggagttt ttccaaaaga taaacctgaa taccgttggt
    14641 caacttttaa aaatatagga gatgctcagg aagtttatcg tttaatgact caggagattt
    14701 ttccgtttat taaaaatctc aagggggata cagatgatac agccttttca cgatatatgc
    14761 gagaagctat ttttcaaata aataaacctg ctacgcttca aaaggcaatt tctatcttag
    14821 atgtttttcc aactagggga ttagatgtag attttgataa tgacaaacaa agtattactg
    14881 atatcggaga tatctatgaa tatctgttat caaaattgtc gaccgcaggt aaaaatggac
    14941 agttccgtac acctcgtcac atcatcgata tgatggttga gttgatgcaa ccgactatca
    15001 aagatatcat ctcagatccc gctatgggtt ctgctggctt cttagtatct gctagccgtt
    15061 acttaaagcg taagaaagat gaatgggaaa ccaatacaga taatatcaat cattttcata
    15121 atcagatgtt tcatggaaat gatacggata cgactatgtt gagacttggg gcgatgaaca
    15181 tgatgctaca tggagtagaa aatccacaaa tcagttacct tgactcgctg tctcaagata
    15241 atgaagaagc cgataaatat actttggttt tagcaaatcc tccttttaag ggctcacttg
    15301 actacaattc aacctctaat gaccttcttg caaccgtaaa aaccaaaaaa acagaattac
    15361 tctttctttc tcttttcttg cgaactttaa aaccaggtgg acgagcagca gttatcgtac
    15421 ctgatggtgt cctttttggt tcgtctaaag ctcataaagg aattcgtcag gaaattgtag
    15481 agaatcataa gcttgatgct gtaatctcaa tgcctagtgg tgtgttcaag ccttatgctg
    15541 gagtttcaac tgctattctc atctttacaa aaactggtaa tggtggtact gacaaagtct
    15601 ggttttacga tatgaaagcg gatggtttaa gtttggatga taagcgacaa ccgattagcg
    15661 acaatgatat tccagatatt atcgaacgct ttcatcatct tgaaaaagaa gcagaacgtc
    15721 agagaacgga tcaatctttc tttgttccag ttgctgagat aaaggaaaat gattatgatt
    15781 tgtctatcaa taaatataaa gagattgagt atgaaaaagt tgagtatgaa ccaacagagg
    15841 tcatcttaaa gaaaatcaat gatttagaaa aagaaattca agctggcttg gctgaattag
    15901 aaaaattact caagtaggga ggtggctgta tgaaaaaagt gaagttgggg gaagtcttat
    15961 ctctaaaaaa aggaaagaaa gccactgtac ttgctgaaca aacaactcta agccaacgtt
    16021 atattcaaat agatgattta agaaataata ataatttaaa attcactgaa agtttaaata
    16081 tgactgaagc actcccagat gatattctaa tagcatggga tggtgctaat gcaggaacag
    16141 ttggctatgg gttatcggga gctgttggta gtacaattac ggtcttaaaa aagaatgagc
    16201 gatacaaaga aaaaattata tcagattact tgggagtctt tttggaaagt aaatcgcagt
    16261 atttacgaga tcattcaaca ggtgcaacta ttcctcattt aaacaagaat atattacttg
    16321 atttacaatt agaattgcta ggtatcgaag aacaagagaa cattatctgt attcttaata
    16381 cgattaaaag gcttattact aaaagaaaat ttcagttaga tgaactaaac ttgctcgtca
    16441 aatcccgatt taacgagatg tttggggatc ctttaaataa taacaagaaa tttgcagtaa
    16501 aaacgggaca acagtgtttt aaattttcaa gtggaaaatt tcttgataaa catgatagag
    16561 tttttgaagg ttatcctgcc tatggtggaa atggcattgc ttggaaaagt cgaaaatatt
    16621 taattgataa tcctactatc atcattggtc gtgtaggtgc atattgtggt aatgtaagaa
    16681 ctacccacgg taaggtatgg ataagtgaca atgctatata tataaaagaa tttaagaatt
    16741 ccgatttcaa tcttgtattt ttattagaat taatgaaagt aattgatttt agtaaatttg
    16801 ctgatttctc aggtcaacca aagataactc aaaaaccatt agaaaatcag aaatatatcc
    16861 tcccccctct agccctccaa aatgagttcg cagactttgt agccctggtc gacaaatcac
    16921 aattggcaat ccaaaaatct ctggaagaac ttgaaacttt gaagaaatct ctgatgcagg
    16981 agtattttgg ctgatattct gccattgtaa ttacggtaat gatttgttat aatacttcaa
    17041 aggaggaaat cagatggtag taaaaacaag aaaacaagga aattcaatca ccattacgat
    17101 tccaagtgaa tttaatattc caagtggtgt taaatacgaa gcgaaattgt taccaagtgg
    17161 tgagattatc tttactcctg aagaattggg gcagcaggtt tcttatgtat ctgatgatgc
    17221 ctttgactta aatttagata aaatatttga cgaatacgac gatgttttca aagctttggt
    17281 ggaaaaatga caatctatct gacagaaaag caaattgaaa aaataaatgc tttagcaatt
    17341 caacggtatt ctccaaatga gaaaattcaa acagttagtt cttctgcctt aaatatgatt
    17401 gtgaacttac cagaacaatt tgtctttggg aagtctcttt atccaacaat ttttgataaa
    17461 gcaacgatac tatttgtcca attgataaag aagcatgttt ttgctaatgc taataaaaga
    17521 actgctttct tcgttttggt caaattttta caattaaacg gctatcgttt ttctgtaacg
    17581 gtagaagaag cagtaaaaat gtgtgtaacc atcgcagtag aagctttaac tgatgaaaaa
    17641 atgacaagct actccaaatg ggtttctgaa cattctgtta gagaaaaggt caaaaagtaa
    17701 cctagtatgc tggatttgaa tgagcacaag aaaataaatg aacagacaat attagaattc
    17761 tgtaatgcag aaactgatat tgtctctttt tattgatgaa taagaaagtg agaaattatg
    17821 gaatcaaaag ttacaattat catgcaagaa atgttacctc ttttaaataa tgaacaatta
    17881 ctagcgttga gagagagttt agaacatcat ctagtagacg gaaaaaagca gcagaagtat
    17941 tcgaataata acctgttgca actatttatt accgccaagc aggtagaggg ctgtagctca
    18001 aaaacaattc gttattacca gaggacgatt gaaaacttgt ttaatgctat taaagagtct
    18061 gtgacacaac tcacaacaga tgatttaagg agttatttag caaattacca gtctgaaaag
    18121 gattgtagta aggcaaattt agacaatatt aggcgtatat tgtcttcttt ttttgcttgg
    18181 cttgagcaag aggaatatat cattaaaaat cccattcgac ggataaagaa aattaagact
    18241 gagcaaaatg tgaaggaaac ttatactgat gaacatttgg aaattatgcg tgataactgt
    18301 gaaaatttga gagatttggc aataatagac ctactagcat cgacaggtat gcgtgtaggg
    18361 gagcttgtac agttgaatcg ttcagatatt gattttgaaa acagagagtg tgttgtcttt
    18421 ggtaaaggaa agaaggagag accagtatat tttgacgctc ggacgaaaat tcatttaaga
    18481 aattatctta acgacagaaa agatagtcac cctgctcttt ttgtaacgct agttggaaaa
    18541 gcccagagac ttggaattgc tggtgtagag attcgcttaa gaaagttagg agacaaactc
    18601 ggcatacaaa aggttcaccc acataagttc agaagaactt tagcgactaa ggcaattgat
    18661 aaaggtatgc ctatcgaaca agtccaaaaa ctgctaggtc atagcaagat tgacacaacc
    18721 ttggcctatg ccatggtcaa tcaaaataat gtcaagcatt cacaccaaaa attcatctct
    18781 taaaagcaaa ttcccgattt aacgagatgt ttggggaaaa taaaatattt gaaagcattg
    18841 ataacttatt tgatattata gatggtgata ggggcaaaaa ttatcctaaa tcagatgagt
    18901 tgtttagtga ggagtactgt ttatttttaa atacaaagaa tgttactaaa aacggatttt
    18961 cattcgatac aaagcaattt atcactaaaa caaaggataa attacttcga aaaggcaaac
    19021 ttgagcgtta tgatatagtc ttgacaacaa gaggtactgt tggaaatgta gcgtactacg
    19081 atgaattaat aaaatataaa catttacgta taaattcagg tatggtaata ttacgtccca
    19141 agacaccaaa tctaaatcag aaatttatta tccatgtttt aaggaataat aattatagtc
    19201 gagtgatatc aggaagtgct cagcctcagt taccaattac aaaattaaaa aaaatacttc
    19261 tccccctccc cccactagcc ctccaaaatg agttcgcaga ctttgtagtc caggtcgaca
    19321 aatcacaatt tgcttgtgag atagctatat aaaagtgtgg agaaatagct tgaaatttag
    19381 tataatatag ctaaactatt tgtttaaagt gagaaaaaaa tgggaaattt tagctttctt
    19441 ttaaaaaatg acgaatatga atctttttca aaaccttgca ttgaagctga gaatatgatt
    19501 gctacatcaa ctgtggctac tgcctttatg gcgcgtcgtg ctttagagca ggctgtccat
    19561 tggatatata gtcacgattc atatttagaa gctccctatc gtgctactct atcttcttta
    19621 gtatgggatg atgattttag ggatatcgta gattctgaac tccacaagca gatagttctg
    19681 ttgattcggt ggggaaacca tgctgctcat ggtggtgaaa ttaaggaacg agaagcgatt
    19741 ttagctttgc atcatttgta tcagtttgtt aattttatcg attattgtta cagcaatgag
    19801 tttgtggagc gttattttga tgagaagtgc ttaccacttt cagcaaacat caaataccga
    19861 gaaactccac aatctatgat aaagttacaa gacagtttac cagaactgcc tgattttcat
    19921 gaacagatgg ctgctcagtc cgtagaagtt caagagactt atactgaaaa acgtgagact
    19981 gcagcgcaac ggcaagatgt gcctttccat attgatcaat tatctgaggc agagacaaga
    20041 aagctcttta ttgatatcga tctccgttta gcaggatgga tatttggaga aaactgttgt
    20101 gttgagatag ccgttgatgg tctcaagcac ggttcaggaa ttggttactg tgactatgta
    20161 ctttatggta aaaatgggaa aattttagcg attgtggagg ctaaaaaagc ctctgtcaat
    20221 ccagaagtag gggaagtaca ggtcaaagaa tatgctgaag ctttggagaa acatatcggc
    20281 tatcagccaa tttgctttat tacaaatggg ttgaagcact atatacttga tggtccgaac
    20341 cgacgccaga ttgcaggctt ttactctcaa gaagaattgc aattagtgat ggatagacgt
    20401 catcttcaaa aaccacttga ggatatttct agtaaaatta gggacgatat ttccgggcgt
    20461 cactaccaaa aacatgccat tgcaagcgtt tgtgaagctt tctctaatca tcgtagacag
    20521 gcacttttgg ttatggcaac tggggcgggg aaaactcgta cagcagtttc tctagttgat
    20581 atcttatcac gtcataactg ggtaaaaaac gttctcttct tagccgatag aacttccttg
    20641 gttaagcaag cctatgattc gtttagaaaa ttactcccag atctttccgt ttgtaacttc
    20701 ttagaagata aagaaggagc tcaatcaagt cgtatggtct tttcaactta tccgaccatg
    20761 attggagcga ttagtggtca agaagaagta aatcaacgcc cttttactgt tgggcatttt
    20821 gaccttatca taattgacga atctcaccgt tctatttatc agaaatacaa gtccattttt
    20881 gattattttg atgcaagaat tgtaggctta acagctactc cgcgtcaaga tttagataaa
    20941 aacacctatg gattctttaa tttggagaat ggggttccaa catatgcata tgatttggaa
    21001 gaggctgtta aagacggata tttagtagcc tatcattcta tcgaaaccaa actgaaacta
    21061 cctacggatg gtctacatta tgatgatttg tccgaagaag aaaaggaaca ttttgatagc
    21121 aaatttgaag acgatagctg tgaaaaagat attgatggga gtgtatttaa ttcctttgtt
    21181 ttcaataaaa gtacagtaga aattgtttta aatgaactca tgacaagagg aattcagaca
    21241 gcctcgggtg atgaaattgg taaaactatt atttttgcta aaaatcatga tcatgcagaa
    21301 tatatcagag gtatttttaa caaccgctat cctgaaaaag ggagcgacta tgctcaggtg
    21361 attgattata gtattaagca ttatcagacc ttgattgatg attttaaaat tgaggagaag
    21421 tatcctcaaa ttgcgatttc tgtcgatatg ttagatacag gtattgatgt accagaggtt
    21481 gttaatttag tcttcttcaa gaaagtacgc tctaaaacta agttttggca gatgattggt
    21541 cgaggaaccc gtctatgtaa agatttattt ggacctgagc aggataagga aaacttcttg
    21601 gtatttgatt atggggataa ttttgattat tttcgtgcag atccaagaga tggagagggt
    21661 cgtcacattg tttcgttgac tcagcgttta tttaatatca aagtggactt gattcgagaa
    21721 cttcagggac tccaatacca agaagatcag tttgcgagag cataccgtca gcagcttgtc
    21781 tcggaacttc aaggtcgtat agagagctta aatgagttgg acttcagggt tcgtatggtt
    21841 ttagatacag tttatagcta taggaaattg gaaagttggc agaatctaac tgctgttaca
    21901 agtgaaacca ttcaaaaaaa tctctctccg cttttatttg atgaagataa agaagatgag
    21961 atggccagga gatttgattt gtggttgctt catattcagt tggggcaact gacagctaaa
    22021 tcttccactg ttcatatttc ccaagtgatg aagacggcta gagctctttc tgctattggc
    22081 aatatcccgc aggtttttga gcaggctgaa attatcagga aagtacagga gcctgaattt
    22141 tggaaagaag ttaacttgtc tgatttggaa aaaattcgtc ttgctattcg agatttatta
    22201 cagtttttgg ataaaacaga ccgtaaaccc tactatgtta actttgaaga tcgtatactc
    22261 tccactgttc acgagaccac agcatttttg caggtcaacg atcttcggtc ttacaatgaa
    22321 aaagttgagc attatttgaa aactcatctg gatgaggagt ccatttctaa gctataccat
    22381 aataaaaagt tgacatctga tgatatgctt gcacttgaaa aattgctttg ggaaaaatta
    22441 ggtagtaaag cagactacca aagtcattat gaaaataagg caattccgag attggttcgt
    22501 gagattattg gcttagatag agagtctgcc aatcgtattt tttctaaatt tttgtcggat
    22561 gagaatctta atgccaggca gatttcattt gtaaaattga ttgtagacta cattgtagaa
    22621 aatggttttt tagagacgaa agtgttaacg caagagccgt ttaaatctta tggttctgtt
    22681 caactactct tccaacacca actaccagta cttcgtaata ttgttcaaat cattgaactt
    22741 atcaataatc gagctggaga agcggcttaa attctaaagt gattgccatg ctgagactca
    22801 tttaaaatta aaaagagtag aaatttatgc tatatatgag aagttttatt aggaagaatg
    22861 tcatcgtttt cctagaatac agtatcagtt gttaagtggt tgataaattt caaagtagat
    22921 acttgtacca cgatgtttgt tgatcgagtt attaacaaaa gagctacttt gattttaaag
    22981 aaatagaaaa caaaaagccg agcaagaatt caattgcagg agaaaatgaa ataatactca
    23041 atgaaaatca aagagcaaac taggaaacta gctgcaggct gctcaaaaca ctgttttgag
    23101 gttgcagata agactgacga agtcagctca aaacatggtt ttgaggttgt agatgaaact
    23161 gacgaagtca gtaaccatac ctacggcaag gcgacgttga cgcggattga agagattttc
    23221 gaagagtata aatcttccta ggataaagca aaacgcatag tatcaagggt tttcaacact
    23281 tgatactatg cgttttctga tgttaaagac tttctaccag tttttttaag cataattgtt
    23341 agttgtagtc atttattatt cttcaaagaa aaatggtggg gcgaattttt tcagttcttc
    23401 aaagcacttt tgagcagtat ctgcatcttc acagatgata agacagacat cattaccaca
    23461 aagggtagcg atagcgtcag ggaagctcaa agtatcaatg atagaaccaa aggattgagc
    23521 cagtccagga agggttttta gtaggacttg gtgttgaact gggcgcatcc agacaagggc
    23581 gtcttccatg tagagttcga gacgtttttc ccattttgag atggaaccat tgttaagaac
    23641 ataataagcg ctatcttctt cgcggacttt tgataggttc atatttttga tgtcgcgtga
    23701 gagggttgcc tgggttactt gaatgtcgtt cttagcaaga agggcttgca actcagcctg
    23761 tgtatgaatc ttgttttttg tgataagagc gcgtataagt tggtggcggt gttctgattt
    23821 attcataata atgtaactcc ttttagcaag gtaaggtaag catggactga gcgaggtcga
    23881 cagtcaagtg gtagtctgta ttgtcacgga tggtgatttc aaagtcagta gtatagagga
    23941 ctaaacggag agtgtctcct tcttttagct tgtaaatagt tggctgcagt tcaaattgaa
    24001 catccatcca ttcatctgca gtaatatcct ctactaacag taaatcattt ctattttgta
    24061 aattaaggta accttttgtc acgactcgtt gtgcctctgg tctaaatggc aattcacaga
    24121 gattttccaa catgtgatag cgaccgttgt caatggttct agcacttaaa atagctggat
    24181 aaggttgtag gtatttcttt tgcccaaatt ctagcagttg ggcagataag agccccttgt
    24241 ttgtactgga tttgatacga agattgagct gagcgcgacc gtttaggtgg agatctttag
    24301 tcacaggaag gttaatagta atctgattgg ctttcccttg atagagctct gtattgaagg
    24361 tttggtatgt cttaccatag cgctcaaaat ccttatctgg gtactggttt tgaatagctt
    24421 gctcttcttg accaagtgag aaggtttcac agttttcttg cccaccgaag ttatcaagtg
    24481 ataaccaagt ctgtggagct gtattgtcct gccagataac agtaggaagt tgaaagtctg
    24541 tttcctgtcc tagtaatttc ttggtcaata aggcatttat ggactcacgg aagtcaattg
    24601 attgccaatt gttcatgtaa acatgggcac cattatggaa aaagagatgc ttgtttatat
    24661 gagtaggaag agcatggaac atctggtaaa catgaagtgg tttgacattc caatcctgag
    24721 aaccatgagt aaagacaacc tctgccttta ctttatgggc attgagcaga taattgcggt
    24781 catgccaaaa ctgattgtag tccccagttt ttcggtctag ctgagctttc actttttcta
    24841 agtcagcttg gtgagcttca ttgccacgga tatagtcgcc agctaagaga ttacgagaat
    24901 aggttaactc agcaagggag tcaaagtcct cacctggata accacctggg ctagtcacca
    24961 gaccgttttc acggtagtag ttgtaccatg atgaaattcc tgcctcggca atgataactt
    25021 ctaaaccatc gactcctgta gtcgcaagac cattggacat ggtacctaga taggaaagtc
    25081 ctgttgtagc aacttttccg tttgaccaat cagccttgac ttgacgctgg cgcgtgtgat
    25141 cagtaaaggc acggcaacgg ccgttaagcc aatcgatgac atttttataa gcctcgattt
    25201 gctggtagtc tccattagtc atgaaacctg tcgagtcttt ggtaccaaca cctgagacat
    25261 agagattggc aaagcctctc ggaaggaagt agtcgtttag tgtatagcta gagttgatgt
    25321 gagttagctt ttcctcagcc tctgctataa gctcagcttt accttggggt tggacgagat
    25381 ttagttgagg tttctctagc tcaatcttgt gaggaagctt aacctcaagc tcgccctcca
    25441 tcttgtagag agccttgtca ctagccttgt cattggttcc ctgatgataa gggctggctg
    25501 tcatgatggc agggattttt ccatcaaaac gagggcgaat aatgctaacc tttactaggt
    25561 ctgatagccc tttttggtca gtatcgacac gagactcaac gtaaacgact tcacgaatga
    25621 catcctggtt agaaaaagta gccaaactct tgccgttaaa gtagtggtag tcattatcct
    25681 ccggaataag accatcacta acaagttggt cgataagagt atttcctttt ttggtgcgag
    25741 tattgagtaa ctgatagaga ttttcaatca agtcaccata tataatggga aatccagttt
    25801 ctttacgaaa aacgtcacta tcttcgaagt caaccaaata agaaaagcct aaaagttgaa
    25861 aagcaacagt ataaaaaata tctgctgtca gttcatcttc tgattgaaaa aatgtcagca
    25921 ggtctgtttt tttatcagct gctaggatag aaagtgggta gttggtgtct tgataagtga
    25981 aaaagaaacg acgtaaaaag gtttcaagtg agtctttgtg attggctgta ttttgtaaat
    26041 caaagccaca tttttttagt tcagataaga cattttcttt tggaaaattg atataactat
    26101 attgattaaa acgcatagaa cctccatata gaatgacagt taaggttatt atatcaaaaa
    26161 aaaagcagaa agggaattgt taacttcaaa aggaaataat ccaataaaaa tgaataaagt
    26221 actaaattca atatagagaa cagagtaaca ataagaataa atagataggg tataaaagtt
    26281 ctaggagatt tatattatat gctttctatt tttatataca atatagtata aatataaaaa
    26341 tgatgacaaa aatacaaatg aatagaaaat aaattagtaa gctgatgaaa tttttctcaa
    26401 gagaagccat ttataggtga aaatggtata atatagtgag aaggatagag gagaagtgta
    26461 aattgatcgc acaactagat acaaaaacag tctatagttt tatggaaagc gtcatttcga
    26521 tcgaaaagta tgtgagagca gctaaagaat acggctacac tcatttggct atgatggata
    26581 ttgacaatct ttatggcgct ttcgactttc tagagattac aaaaaaatac ggcattcatc
    26641 ctttgctagg gcttgaaatg acagtgtttg tagatgatca ggaagtgaat ttgcgctttt
    26701 tagctctatc tagtgtgggc tatcagcagt tgatgaagct ttcgacagcc aagatgcagg
    26761 gggagaaaac ttggtcagtc ctgtcccagt acctggagga tatcgcggtc attgtgcctt
    26821 attttgatag agttgagtcg ttagaactag gctgtgatta ctatataggg gtttatccag
    26881 aaacactagc aagcgaattt catcatccta tcttacctct ttatcgggtc aacgcttttg
    26941 aaagcaggga tagagaagtt cttcaagttt taacagcgat taaagaaaat ctaccgctca
    27001 gagaagttcc cttgcgttcg agacaagatg tctttatatc agcaagttct ttagagaaac
    27061 tattccaaga gtgttttccg caagctttgg acaatttaga aaagcttatt tcaggcattt
    27121 cttacgactt ggatactagt ctgaaactgc ctcgttttaa tccagctaga ccagcagtag
    27181 aggagttgag agagcgtgct gaactggggc ttgttcagaa ggggttgact agtaaagaat
    27241 atcaagatag actagaccaa gaattgtctg ttattcatga tatgggcttt gatgattatt
    27301 tcttggttgt ttgggatttg ttgcgttttg gacgatcgaa tggctattat atgggaatgg
    27361 gaaggggttc tgcagtaggc agtttggttt cttatgcctt agacatcacg gggattgacc
    27421 cagtagagaa aaatctgatt tttgaacgct ttcttaatcg tgaacgctat accatgcctg
    27481 atattgatat tgatatccca gatatttatc gtccagattt tatcagatat gttggtaata
    27541 aatatggtag taaacatgcg gcacaaatcg ttactttttc aacctttgga gccaagcaag
    27601 ctcttcgaga tgtcttgaaa cgctttggtg tgccagagta tgaattatct gcaattacta
    27661 agaaaatcag ttttcgtgac aatcttaagt cggcctatga gggcaatctc cagtttcgtc
    27721 agcaaatcaa tagtaagtta gaataccaaa aagcttttga gattgcttgc aagatagagg
    27781 gctatccaag acaaacctct gtccatgcgg ctggtgttgt aattagtgac caagatttaa
    27841 ccaactatat tcctctaaag tatggtgatg aaattccact gactcagtat gatgctcatg
    27901 gagttgaggc tagcggactt ttgaagatgg actttctggg actacgaaat ttgacctttg
    27961 tccagaagat gcaagagttg cttgctgaaa tagaaggtat tcaccttaaa attgaagaaa
    28021 tagatttgga agacaaagaa acgttagctt tatttgcctc tggaaataca aaaggtatct
    28081 ttcaatttga gcaaccaggt gccattcgtc tgcttaagcg tgtgcaacca gtctgttttg
    28141 aagatgtcgt cgcgactact tctctaaatc gaccgggtgc tagtgactat atcaataatt
    28201 ttgtggcaag aaagcatggg caggaagaag tgactgttct ggatccagta ctggaggata
    28261 ttttggctcc aacctacggc ataatgctct atcaggagca ggttatgcag gttgcccagc
    28321 gatttgccgg atttagtctt gggaaagccg atattttgcg tcgggctatg gggaaaaagg
    28381 atgcctctgc catgcatgag atgagggctt cctttattca aggttcatta gaagctggtc
    28441 atactgtgga aaaagcagag caggtctttg atgttatgga gaagtttgca ggttatggtt
    28501 ttaacaggtc acacgcctat gcctactcag ccttggcctt ccagttggct tattttaaaa
    28561 cacattatcc agccattttt tatcaggtca tgttaaattc ttccaacagt gattacttaa
    28621 tagatgcact tgaagcaggt tttgaagtag cctctctatc catcaacacc attccctatc
    28681 acgataaaat tgccaacaag gccatctatc taggtttgaa atccattaaa ggagtcagta
    28741 atgatttagc tctctggatt attgaaaata gaccttattc taacattgaa gattttatag
    28801 ctaaattacc tgagaattat ctgaaacttc ctctgctaga acctttggta aaagttggtc
    28861 ttttcgattc atttgaaaaa aatcgtcaaa aagtatttaa taatttagct aatctatttg
    28921 aatttgtgaa agagttggga agtttgtttg gagatgctat ttatagttgg cagaaatcgg
    28981 aagattggac ggaacaagaa aaattttata tggaacaaga gcttttaggg ataggtgtca
    29041 gcaaacatcc actacaagct attgcaagta aggctattta cccgattacc ccaatcggaa
    29101 atttgtcaga aaatagctat gctattattt tggttgaagt tcagaaaata aaagtgattc
    29161 gtaccaaaaa gggtgaaaat atggctttct tacaggtgga tgacagtaag aaaaaattgg
    29221 atgttacact cttctcagat ttatatcgac aggttggtca ggaagtaaga gaaggagcat
    29281 tctactatat caaagggaaa gtccaatcac gtgacggtcg tctgcaaatg attgcacaag
    29341 aaataagaga agcagttgct gaacgctttt ggattcaggt taaaaatcat gactcggatc
    29401 aagagatgtc acgtatttta gaccagtata aaggcccaat cccagtcatc atccggtatg
    29461 aagaggaaca gaaaaccatc gtttctcccc atcattttgt agctaaatct gatgaattag
    29521 aggcgaaatt gaatggaata gttatgaaaa cgatttatcg ctaaaattac ggaaaataga
    29581 agaattttca acgtaaatgt ggtataatca gtaagaatgt taaaagaaaa aggagcataa
    29641 ccaatatgaa acgtattgct gttttgacta gtggtggaga cgcccctggt atgaacgctg
    29701 ccatccgtgc agttgttcgt caagcaattt cagaaggaat ggaagtgttt ggtatctatg
    29761 acggatatgc tggtatggtt gccggtgaaa ttcatcccct agatgcagct tcagtagggg
    29821 acatcatttc tcgtggtggt actttccttc actcagctcg ttacccagag ttcgctcaac
    29881 ttgaagggca acttaaaggg attgagcaat tgaaaaaaca cggaattgaa ggtgtagttg
    29941 ttatcggtgg tgacggatct taccacggcg ctatgcgttt gactgaacat ggcttcccag
    30001 ctattggtct tccaggtaca atcgataacg atatcgttgg tactgacttt acaatcggtt
    30061 ttgacacagc ggttactact gccatggacg ctatcgataa gattcgtgat acatcatcaa
    30121 gtcaccgtcg tacttttgta atcgaagtta tgggacgtaa cgctggtgat atcgctcttt
    30181 gggctggtat tgcaactggt gctgatgaaa tcatcatccc tgaagcaggc ttcaagatgg
    30241 aagatatcgt agcaagcatc aaagctggtt atgaatgtgg taaaaaacac aatatcatcg
    30301 tcttagctga aggtgtgatg tcagcggctg aatttggtca aaaacttaaa gaagctggag
    30361 atacaagcga ccttcgtgta acagaacttg gacatattca acgtggtggt tctccaactg
    30421 cgcgtgaccg tgttttggcg tcacgtatgg gtgcacatgc tgttaaactt cttaaagaag
    30481 gtatcggtgg tgttgcggtt ggtattcgta acgaaaaaat ggttgaaaat ccaattcttg
    30541 gtactgcaga agaaggggca ttgtttagcc ttactgcaga aggtaagatt gtggttaaca
    30601 acccacacaa agccgatatt gagctatcta gcttgaataa gagcttgtta taatttacaa
    30661 tttagttaat aagaccaaaa aggtcatata tataaaggag tcacaaaaat catgaacaaa
    30721 cgtgtaaaaa tcgttgcaac tttgggtcct gcggtagaaa tccgtggtgg taaaaaattc
    30781 ggtgaggacg gatactgggg tgaaaaactt gatgttgaag cttcagctaa aaacattgct
    30841 aaattgattg aagctggtgc taacacattc cgattcaact tctcacacgg cgaccaccaa
    30901 gaacaaggtg agcgtatggc aactgttaaa cttgcggaaa aaattgcagg taaaaaagtt
    30961 ggtttccttc ttgatacaaa aggacctgaa atccgtacag aattgttcga aggtgaagct
    31021 aaagaatatt catacaaaac tggtgaaaaa attcgtgttg caactaaaca aggaatcaaa
    31081 tcaactcgtg aagtgattgc gttgaacgtt gctggtgctc ttgatatcta tgatgatgtt
    31141 gaagttggtc gtcaagtttt ggttgacgat ggtaaacttg gtcttcgtgt ggttgctaaa
    31201 gatgatgcaa ctcgtgaatt tgaagttgaa gttgaaaacg atggtatcat cgctaaacaa
    31261 aaaggtgtga acatccctaa cactaaaatt cctttcccag ctcttgctga acgcgataac
    31321 gacgatatcc gtttcggtct tgaacaaggt atcaacttca tcgcaatttc attcgtacgt
    31381 actgcaaaag atgtgaacga agttcgtgca atctgtgaag aaactggaaa cggacatgtt
    31441 caattgttcg ctaaaatcga aaaccaacaa ggtatcgata acttagacga aatcatcgaa
    31501 gcagctgatg gtattatgat tgctcgtggt gatatgggta tcgaagtacc gttcgaaatg
    31561 gttccagttt atcaaaaaat gattatcaag aaagtcaatg ctgcaggtaa agttgttatc
    31621 actgcaacaa acatgcttga aacaatgact gaaaaaccac gtgcaactcg ttcagaagta
    31681 tcagacgtat tcaacgctgt tatcgacgga actgacgcta caatgctgtc aggcgagtct
    31741 gcaaacggta aatacccact cgagtcagta actacaatgg ctacaatcga caagaacgct
    31801 caagctcttc ttaatgaata cggacgtctt gattcagatt catttgagcg taactctaag
    31861 acagaagtaa tggcttctgc tgttaaagat gctactagct caatggatat caaattggtt
    31921 gtaactctta ctaagacagg tcatactgca cgtttgattt ctaaataccg tccaaatgct
    31981 gacatcttag cattgacatt tgacgaattg acagaacgtg gcttgatgtt gaactggggt
    32041 gttatcccaa tgttgacaga tgctccatct tcaactgacg atatgttcga aatcgctgaa
    32101 cgtaaagcgg tagaagcagg tctcgttgag tcaggcgatg atatcgttat cgttgctggt
    32161 gtgccagtag gagaagctgt tcgcacaaac acaatgcgta tccgcacagt acgttaagaa
    32221 aaatataaaa acctatcata tccagctttc tagcctgtat gatgggctct ttttttgtcc
    32281 agggggcaaa aagggggcaa aactttcata atggattgat actcttcgaa aatctcttca
    32341 aaccacgtca gcgtcgcctt accgtatata tgttactgac ttcgtcagtt ctatctacaa
    32401 cctcaaagca gtgctttgag caacctgcgg ctagcttcct agtttgctct ttgattttca
    32461 ttgagtatga aataagatat gcacaaattg attaggaaat tcaaatgaat ttctacaaat
    32521 gttttagcaa tcgcaatcta cttgtctaga ttcgatctga tatattttcg atttaatgat
    32581 atggtattta aaacctccaa agtagcttgc tccattcttt tacttacgtg agtgtagatg
    32641 ttatttactg ttttagcgtt tttgtgttct actctaacca ttatagcatt cttctcagct
    32701 agtgtactaa ggagtgtgtg cctgaaaata tgggaactaa gggctggttt atcggtttct
    32761 ctagtttagt atttgccttt tgcaaagtga tcttaaatgc ctttctctaa atttacatat
    32821 cactattgtt taacaaaatc taatctactt taggtcactt attctttttt tgaaatgtag
    32881 aatgaacttt ttcaaagttt ttcgaatctt ttaaaatctg tttgttttat atcgccattc
    32941 tccccctttt ttaattctcc ctatatagcc tgacaacttt cccgatggta cgaatatggt
    33001 tgctttcgtc taggtggatg tcggagtatt cgggattgag tttttttgag gtagccttgg
    33061 cggagtttct tgacatagtt agtgccgtct acttggaaga tgccgatggt attatagtca
    33121 atctgtgggg tattcttgat aaataggtag tcgctgtttc ttatctttgg ctccatggac
    33181 ttgctgacga cataagcgat tgggtcgtag tcgtctggga taatggaaac tccataacta
    33241 aatcgtcgtc ctgcatcaag cggctacctg cagagataaa ctacctaaca cgagagtaag
    33301 tagtctgtct gtagtcgtcc agtctgatga tttttacgat acttcgtttt tctgatcata
    33361 cagttgcctc tcggcatagg tcagaacttt accttgtctg ggtggtgccc gttggtcgta
    33421 gatagattgg atatcgctag gagaatcctt ttgaactgga ggaaagaggg catcaatcaa
    33481 gctactgaat actttaacta agtcaaatat agtatttttc ttagtagacc taaccctttt
    33541 ttcataattt ctaatggtgt ttttacttat acctatctta gtacccaatt cttattgagt
    33601 ccaaccatta ctagtctata ttgttttata gttgattgag tttggaatag tacgctgtag
    33661 ctgctaaaac atttctagga attaatttgc ctttcctaat agagttgttc atatcttatt
    33721 tcaatctact atatttttca cctctaacaa tcgcaatctc ttctttatcc atgaacgaaa
    33781 acgctttcta tctttgtaag taaagcatca cacgaaatcc acgaaaatga aaacctttgt
    33841 tgtgttttcg taaaaaattt gttgacagag cacgaaacgc ctactataat taaatcaagt
    33901 ttaaggaaat aacaaaaaaa caaatcggag ggaaagacga tgaacacatt aaatgagaaa
    33961 gtaatcaata tctgtaaagc agtagttaaa gaaactttaa tccaagacat ttaggagaaa
    34021 gaaatgaaga aatcaagaaa attagccaca ttaggaatct gttcagcctt gtttttaggc
    34081 ttggctgctt gtcaacaaca acatgctact tctgagggga cgaatcaaag gcaaagcagt
    34141 tcagcgaaag ttccatggaa agcttcatac accaacctaa acaaccaggt aagtacagaa
    34201 gaggtcaaat ctctcttatc agctcacttg gatccaaata gtgttgatgc attttttaat
    34261 ctcgttaatg actataatac cattgtcggc tcaactggct tatcaggaga tttcacttcc
    34321 tttactcaca ccgaatacga tgttgagaaa atcagtcatc tctggaatca aaagaagggc
    34381 gatttcgttg ggaccaactg ccgtatcaat agttattgtc ttttgaaaaa ttcagtcacc
    34441 attccaaagc ttgaaaagaa tgaccagttg cttttcctag ataatgatgc gattgataaa
    34501 ggaaaggtct ttgattcaca agataaggaa gagtttgata ttctattttc gagagttcca
    34561 actgaggcaa ctacagatgt caaggttcac gctgaaaaga tggaaacatt cttctcacaa
    34621 tttcaattca atgaaaaagc tcgaatgctg tctgtagtct tgcacgacaa tctggatggc
    34681 gagtatctgt ttgtaggtca cgttggggtc ttagtacctg ctgatgacgg tttcttattt
    34741 gtagagaaat tgactttcga agaaccctac caagcgatta aatttgctag taaggaagat
    34801 tgctacaagt atttgggcac caagtatgcg gattatacag gcgagggact ggctaagcct
    34861 tttatcatgg ataatgataa gtgggttaaa ctttaatagt gttatgatat gacagtaatc
    34921 ttaggatttt tatttctatt tttgatgact tggtgggtta tttcaatcgt taatagccag
    34981 aaaccactca aaaatgaaac atttattggc tatgtccaaa gatacgatat tgatgggaat
    35041 ggctatcaat cattaccgtg tcctcagaac tgagaggagt tcttgaaatc gtaacaccac
    35101 tttgaacaag agttacttca acccattggc tccgccggag taagttgctt tcgtgaacac
    35161 caaaatcagc cgcaatttct tcataagtgc ggtattctca cacatattga agagtggcca
    35221 taagaaggtc ttctaggctt aatttaggtt ttcgtccacc ttttgcgtgt ttaagttgat
    35281 aagctgtttt taatacagct aacatctctt caaaagtggt acgctgaaca ccaacaagac
    35341 gcttaaatcg tgcatcagtt agttgtttac ttgcttcatc attcatagaa ctactatacc
    35401 atattttgtt tcgcaggaag tctaatgcta aaatcttatc agtgagaaga tttcttaaag
    35461 tttattcttt gtagtttcat ctgtattagt acataattta acttagagaa aataggagga
    35521 ctaatcgaat ggaattaaaa gattttacag aaaaagaaca ggaaatgatt aagaaaaggc
    35581 ttacaatgtc taatattagt gacaaagaaa ctactgagaa gattctggcg ctagtaccac
    35641 aagacttgat taagcgaatc ccgttttttg tcagaaaaca tgctacaaca cgtacgatta
    35701 aacgcatttc aattgaatac cctgaactct acgctgtagc tcaaacaagt ggtgagattc
    35761 cagaaaaaga acgcgaagaa ttgcgtcaga ttatcacaac tatctttgaa caaaagatga
    35821 ataagcatag tattaagtag agaatgaaaa aatattttat tagcggtttg ggaagcaatg
    35881 cctatcatag caaggatttt tttcaagaac tagattcgca ggtctatttt ctaaatccat
    35941 atgaaaagca tcttcgagat gaaacagaat tgaaatcatg gtttaaaaat gagattgtag
    36001 aggaagaatc tatctgtctg ataggccatt ctcttggagg agatttagct cgttatttcg
    36061 catcggaatt tgaagaagta aagaaactga ttcttttgga tggtggctat ctagatttag
    36121 ataagatttt acctttggat acagagttag aggaaactaa aaattatatc aaatctcaaa
    36181 ttgtttcgga cttagctctt cttatttcta aagagaagtc cgaagcaaag cattggtcag
    36241 aaaatatgga gaaagctgta agacagtcct atcactggaa tgttgagtat aatagatatg
    36301 agttggctat aaattatgaa aatatagaag cgatactccg cctacggaga aaaatacaag
    36361 cttttaagag agaagtggga gataccttgt ttattagtcc tcgctatcct aatggagcta
    36421 catggagaga ggaagcccta aaagaattgc cagactattt taatactatt tttttagaaa
    36481 actttggcca tgagctttat actcaagcac ctaaagaaat cgctagtcta atgaatgagt
    36541 ggctcgctta ttttctatga gctacttgta ttgctggaaa tggtataaga tgaaaatct
//
LOCUS       DAYYYC010000018        35868 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.018, whole genome shotgun sequence.
ACCESSION   DAYYYC010000018 DAYYYC010000000
VERSION     DAYYYC010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35868
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.018"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(99..1580)
                     /gene="mgaSpn"
                     /locus_tag="ACHBV5_000923"
                     /gene_synonym="mgrA"
     CDS             complement(99..1580)
                     /gene="mgaSpn"
                     /locus_tag="ACHBV5_000923"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HFM9966743.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2023..2187
                     /locus_tag="ACHBV5_000924"
     CDS             2023..2187
                     /locus_tag="ACHBV5_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFM9966744.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            2271..2837
                     /gene="amaP"
                     /locus_tag="ACHBV5_000925"
     CDS             2271..2837
                     /gene="amaP"
                     /locus_tag="ACHBV5_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFM9966745.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            2849..3019
                     /locus_tag="ACHBV5_000926"
     CDS             2849..3019
                     /locus_tag="ACHBV5_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFM9966746.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            3058..3666
                     /locus_tag="ACHBV5_000927"
     CDS             3058..3666
                     /locus_tag="ACHBV5_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFM9966747.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            3697..3900
                     /locus_tag="ACHBV5_000928"
     CDS             3697..3900
                     /locus_tag="ACHBV5_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFM9966748.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(3995..4234)
                     /locus_tag="ACHBV5_000929"
     CDS             complement(3995..4234)
                     /locus_tag="ACHBV5_000929"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM9966749.1"
                     /translation="MNERYQCLKTKEYQALLSSKGRQIFAKRKIDMKSVFGQIKVCLG
                     YKRCHLRGKRQVRIDMGFVLMANNLLKYNKRKRQN"
     gene            4513..4758
                     /locus_tag="ACHBV5_000930"
     CDS             4513..4758
                     /locus_tag="ACHBV5_000930"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFM9966750.1"
                     /translation="MAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFF
                     ANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(5036..5806)
                     /locus_tag="ACHBV5_000931"
     CDS             complement(5036..5806)
                     /locus_tag="ACHBV5_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFM9966751.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(5821..6669)
                     /locus_tag="ACHBV5_000932"
     CDS             complement(5821..6669)
                     /locus_tag="ACHBV5_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HFM9966752.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(6666..8141)
                     /locus_tag="ACHBV5_000933"
     CDS             complement(6666..8141)
                     /locus_tag="ACHBV5_000933"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HFM9966753.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(8464..9819)
                     /locus_tag="ACHBV5_000934"
     CDS             complement(8464..9819)
                     /locus_tag="ACHBV5_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFM9966754.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(9829..10146)
                     /locus_tag="ACHBV5_000935"
     CDS             complement(9829..10146)
                     /locus_tag="ACHBV5_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFM9966755.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(10163..10480)
                     /locus_tag="ACHBV5_000936"
     CDS             complement(10163..10480)
                     /locus_tag="ACHBV5_000936"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM9966756.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(10493..12178)
                     /locus_tag="ACHBV5_000937"
     CDS             complement(10493..12178)
                     /locus_tag="ACHBV5_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HFM9966757.1"
                     /translation="MKNKKLILSLFILFLLIFIHAKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINDNRADGYIGQVIDIEPNEDYLVSAFAKVDIS
                     GAEGYFTARWFDNNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGRGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGSWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRNKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(12183..13079)
                     /locus_tag="ACHBV5_000938"
     CDS             complement(12183..13079)
                     /locus_tag="ACHBV5_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HFM9966758.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNQEIIKAVQSAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(13082..14344)
                     /locus_tag="ACHBV5_000939"
     CDS             complement(13082..14344)
                     /locus_tag="ACHBV5_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFM9966759.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            14624..15802
                     /locus_tag="ACHBV5_000940"
     CDS             14624..15802
                     /locus_tag="ACHBV5_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HFM9966760.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(16030..16476)
                     /locus_tag="ACHBV5_000941"
     CDS             complement(16030..16476)
                     /locus_tag="ACHBV5_000941"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9966761.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVQKYSRLKLE"
     gene            16546..17205
                     /locus_tag="ACHBV5_000942"
     CDS             16546..17205
                     /locus_tag="ACHBV5_000942"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFM9966762.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACGIIFGKLLL
                     V"
     gene            complement(17257..18408)
                     /locus_tag="ACHBV5_000943"
     CDS             complement(17257..18408)
                     /locus_tag="ACHBV5_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM9966763.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGNRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(18423..19154)
                     /locus_tag="ACHBV5_000944"
     CDS             complement(18423..19154)
                     /locus_tag="ACHBV5_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966764.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            19383..19484
                     /locus_tag="ACHBV5_000945"
                     /pseudo
     CDS             19383..19484
                     /locus_tag="ACHBV5_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(19456..20232)
                     /gene="trpA"
                     /locus_tag="ACHBV5_000946"
     CDS             complement(19456..20232)
                     /gene="trpA"
                     /locus_tag="ACHBV5_000946"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HFM9966765.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(20225..21448)
                     /gene="trpB"
                     /locus_tag="ACHBV5_000947"
     CDS             complement(20225..21448)
                     /gene="trpB"
                     /locus_tag="ACHBV5_000947"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HFM9966766.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGCPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(21426..22025)
                     /locus_tag="ACHBV5_000948"
     CDS             complement(21426..22025)
                     /locus_tag="ACHBV5_000948"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HFM9966767.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     YFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(22012..22779)
                     /gene="trpC"
                     /locus_tag="ACHBV5_000949"
     CDS             complement(22012..22779)
                     /gene="trpC"
                     /locus_tag="ACHBV5_000949"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HFM9966768.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(22776..23780)
                     /gene="trpD"
                     /locus_tag="ACHBV5_000950"
     CDS             complement(22776..23780)
                     /gene="trpD"
                     /locus_tag="ACHBV5_000950"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HFM9966769.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIITGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(23791..24357)
                     /locus_tag="ACHBV5_000951"
     CDS             complement(23791..24357)
                     /locus_tag="ACHBV5_000951"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HFM9966770.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQTIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            complement(24354..25715)
                     /gene="trpE"
                     /locus_tag="ACHBV5_000952"
     CDS             complement(24354..25715)
                     /gene="trpE"
                     /locus_tag="ACHBV5_000952"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HFM9966771.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEELEKALNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPQKFEEMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(26636..27637)
                     /locus_tag="ACHBV5_000953"
     CDS             complement(26636..27637)
                     /locus_tag="ACHBV5_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM9966772.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(27745..28113)
                     /locus_tag="ACHBV5_000954"
     CDS             complement(27745..28113)
                     /locus_tag="ACHBV5_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966773.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            complement(28209..28919)
                     /locus_tag="ACHBV5_000955"
     CDS             complement(28209..28919)
                     /locus_tag="ACHBV5_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFM9966774.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(28922..30613)
                     /locus_tag="ACHBV5_000956"
     CDS             complement(28922..30613)
                     /locus_tag="ACHBV5_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9966775.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(30625..31635)
                     /locus_tag="ACHBV5_000957"
     CDS             complement(30625..31635)
                     /locus_tag="ACHBV5_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966776.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(31739..32806)
                     /locus_tag="ACHBV5_000958"
     CDS             complement(31739..32806)
                     /locus_tag="ACHBV5_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFM9966777.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(32831..33490)
                     /locus_tag="ACHBV5_000959"
     CDS             complement(32831..33490)
                     /locus_tag="ACHBV5_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HFM9966778.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            complement(33654..34664)
                     /gene="galE"
                     /locus_tag="ACHBV5_000960"
     CDS             complement(33654..34664)
                     /gene="galE"
                     /locus_tag="ACHBV5_000960"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFM9966779.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNIFE
                     SVNKIPIPYKIVPRRSGDVATYYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            complement(34677..>35868)
                     /gene="galT"
                     /locus_tag="ACHBV5_000961"
     CDS             complement(34677..>35868)
                     /gene="galT"
                     /locus_tag="ACHBV5_000961"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFM9966780.1"
                     /translation="SSYDISPQEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGEL
                     EITINLSKPEKDPKTIAAEKLVKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKL
                     GDEVWGFQYSPYSYFNEHAIFLNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLP
                     ISGGSILSHNHYQGGKHIFPMEKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKN
                     RLLDLATKILNKWREYSDLEVDIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTT
                     EQYPDGVFHPHQDVQHIKKENIGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADY
                     HLEWADQLKEKYPRINKEEVNSVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKS
                     VGIN"
BASE COUNT        11514 a         7379 c         5519 g        11456 t
ORIGIN      
        1 gtcttttctt aacaaaaaca ccccaaaaat tagatttttt ctgtctaact tttgaggtac
       61 agttcaaacg cgaaatagcg tttttttgtt atttttggtt actcatctaa tcgaataaac
      121 atcatggcat ttaacaagta tatgagtgag accgtgttta tattatttga atagatgagt
      181 ctcttatttt caataggagg aataataaaa ttagaaataa tgatatcata aggtgaatct
      241 tctaaagatt cctttgataa ttctaattca gtccaaactt ccagttcaaa attattgcta
      301 cagtaataag aaagtgtctc tgcaacgaat tttgcatgat actgatcaaa attactcata
      361 actaaaacct ttagtttagg ctgattttgt agcaaattaa tcaccaaatg tttggtatga
      421 gtgatgaagg tataagatag atgatttacc atcattgaac tagaacaaac ctcaagagtc
      481 tctaaatagt gagaaagctc tttttttata tctgaaacaa attttggaaa aatattttga
      541 aagttcctga ttgtattccc tttttgatca aataaaataa actcagtaaa caactcttga
      601 cgatacagat gtgcggtatt atgcagatgc caaatcagat tatccttatt ctccatttca
      661 atctgatact tgactgaaat ctgatcaata aaatcactca atagatggta agatttttca
      721 acataactat ccttttttac gcatttcata aagagacttt catctatgaa aaacattttt
      781 tgaaagtaag acacaaataa ttggcaaaca acttcttcat ctaaagagat attgtattct
      841 gattcaaaac tctgagcaac accttctatt ccttctgcct gcattaaaaa atccaaactt
      901 tggtcgttaa aagaatcttt atctacttcc ataaaatgac caaactttat tctatatagg
      961 ttcgtaacta ggagcaactt tagcattcta tgcgttgaca aattcattgg aaagcttgtt
     1021 tccttataaa ccaattctaa caattgagat agtggctctg atgaaaaatt ttcaaatggc
     1081 cattctagga aataatattt ttctgaaaaa tattgtgcaa aaaagtaacg aatgtctctc
     1141 tcatttccaa tgatttgaac aggggtcaga ctgacttcaa attgaaattg ccttttaatc
     1201 actttattga tttggctaat aatacgatag agcgaagatg aactgatata aaattcttta
     1261 caaatactct cagcttgaca accttcatta aagaagatga attctaaaat cgaaaaatga
     1321 gttgaatgtt taaagaaatg atggtaaacc atttcaatat cactatcatc ggtattaata
     1381 atgcgtatac cattagtaga agaatgaaaa atcaagtcag gaaaagcaga tttaacatgg
     1441 gatagatcat ctttgactgc acgttctgta caatttaata actctgctag ttcagaacga
     1501 tgaaaccaac gtttatgttc aaataataat tctaataatt ctaattgcct atgacttttt
     1561 ttagataata aatctctcat gaatatcttt ctctctttat aaattatcgg attaaacctc
     1621 ttgcaattat accacaaaga ataggtatag catgatataa cgacttttcc taaaatcttt
     1681 tatttcgtat aataacacta cggagacaat atataaacaa ttttcttatt ttaccgtcta
     1741 ttgagggcgt gaatacagaa tcaaattcaa gtctaaagat tatattttta attttaaaaa
     1801 ttatataata gcaacaatta aagaatttga ttttttaaaa ttatataata ataacaatcg
     1861 aaataattga cttttctata ttaaagttat ataatagtat taatcaaaga aattgatttt
     1921 ttgatattaa aataaaaaag gagggtaggc agtgttgtga tcaattattg ctggaggtct
     1981 tattggtctc ttggcaggta aaatcactaa aaaagtagtt ctatgggaat catcgcaaat
     2041 gtattcgctg gtttagtcgg ggcatatgca ggacaatctc ttttaggtag ttggggtcca
     2101 tcaatcgctg gaatggcttt gctcccatct attgtaggtg cagcgattgt gattactgta
     2161 gtgtcattct ttacaggtag aaagtaaact tttcgccagt aaagttagca aactattttt
     2221 aaatcaatga cgggaaaaat agtttaaatg ttaaatcgaa aggattgtat atgtcaaaag
     2281 caaagaaaat atgtttcatt attttctgta ttttaatctt gacaattttc cttcctgttt
     2341 tgatagatta tcatcaagtt agtgatctag gtattcatct acttagctgg agacagaact
     2401 ccgtagttga attctatctt gctagatatg tcttttgggg gacagtggtt ctatcaactt
     2461 tagttttatt atccatttta gttgtgatgt tttatcctaa acgttacttg gaaatccaac
     2521 ttgaaactaa aaacgataca ttaaaattaa agaattcggc aatcgaaggt tttgttagaa
     2581 gtttggtgag tgatcataga ttgatcaaga acccaactgt tcatgtaaat ttacgaaaaa
     2641 ataaatgttt cgttcatgta gaaggtaaaa ttcttccttc agacaacatc gctgacagat
     2701 gccaaataat tcaaaatgaa ataactaatg gattgaagca gttttttggt attgagcgtc
     2761 aagtaaaact tgaagttgca gtaaaaaatt accaaccaaa acctcaaaac aaaaagactg
     2821 ttagtcgtgt gaagtaagga agtaaaaaat ggaatggctt aaacaatatc gatatccaat
     2881 tatcgctggt ctcataggcg tatttctggc ttgtttgatt gtctcctttg gcttcttcaa
     2941 aacaatattt gtattgattt taggagcact gggagttgca gctggattat atatcgaaaa
     3001 aaactatata gataaataaa aaaataaaaa ttactaattt aattaaagga gtttcatatg
     3061 tcaaacgaaa aaaacacaaa cactaacgta gaaaagaaag atgctactgt tgtagctcac
     3121 gaaatcaaag gggaacttac ttacgaagat aaagttatcc aaaaaatcat tggtctttca
     3181 ctagaaaacg tttcaggtct tttgggaatc gatggtggtt tcttctcaaa tcttaaagaa
     3241 aaaatcgtta acagcgatga cgtaacaagt ggtgttaacg tagaagttgg taaaacacaa
     3301 gttgcagttg acttaaacgt tattgttgag taccaaaaaa atgttccagc tttatattca
     3361 gaaatcagag aaatcgtatc ttcagaagtt gctaaaatga ctgacttgga aattgttgaa
     3421 atcaacgtaa acgttgtcga catcaaaact aaagaacagc atgaagcaga ctcagtaagc
     3481 cttcaagatc gcgtatctga cgttgctgaa tcaacaggag aattcacttc agaacaattc
     3541 gaaaaagcta aatctggtct tggatctggt ttctcaactg ttcaagaaaa agttagcgaa
     3601 ggtgtagaag ctgttaaagg tgcagcaaat ggtgtagtat ctcacgaaaa cactcgtgta
     3661 aactaagata aaataaatat aacaggagaa attatcatgt cagtagaaga aaaattaaat
     3721 caagctaaag gttctattaa agaaggtgtt gggaaagcca tcggtgatga aaaaatggaa
     3781 aaagaaggag cagctgaaaa agttgtttct aaagtaaaag aagttgccga agacgctaaa
     3841 gacgctgtag aaggtgctgt agaaggtgtt aaaaacatgt tgagtggcga cgataaataa
     3901 ggttaaaagt tactttatct ttttggtaac attagtcaag atgattctca gaaaacaaaa
     3961 agctagagat tcccaattgc ggaaccctag ctttttaatt ttgcctcttt ctcttattat
     4021 atttcagcag gttgttggcc atgagtacga atcccatgtc aattctcact tgacgcttcc
     4081 ctctcagatg acatctctta taacccaaac aaacctttat ctgcccaaag acagatttca
     4141 tatcaatctt acgtttagcg aaaatttgtc tacccttgga agataaaagt gcctgatatt
     4201 ctttagtttt taaacactgg taacgttcat tcatatacag tcccttttga ggggctgatt
     4261 caggttcata atcgcagtca acattgattt caaggctgtt tgctttctat ctcccctttt
     4321 tcatgatata ttttcgtaca ggtgcttcaa tagtttctat agtaaaatga accaaaaata
     4381 gtacacgttg cggtataatg ttcttgtggc atattcatta gattttcgta aaaagttctc
     4441 tcctatttgt gagcgaacag gtatagtcaa ttgattgtca gtttgaagac caagagtcgt
     4501 aaggcaaagg atatggcaga atccatccaa gggtggctgg cacaatttct agtgaacctc
     4561 tttaaatcta ttacgtttga ctgtggaaaa gagttttcaa aatggaaaga tatttccaat
     4621 catcacgata gtgagagctt ttttgcgaat ctaggatgtc caagacagcg gtgtctcaac
     4681 gaacattcaa atagactttt aaggtgtcat gacttgccaa agcagacaga tttcaacgaa
     4741 gtcagtcaag aattttaggc tgggtaaaaa ctcaatttca ggagaaaatg aaataaatat
     4801 tcccacaata aaatgcatag tatcaaagtt tttccaacac ctgatattat gcatttttta
     4861 attttaaaga ctttttccca gcctcaagaa atcacatccc acctaaatcc tttggatacc
     4921 aaatacctca tcaggtattt tctgagttgg taagactgtc tagcttaatt tgacaaatgg
     4981 agggcgttaa atccagtttt tacaggaagt ctatttaaat attttcacac tgaccttaca
     5041 aaatatgaaa caaattatat aaagtcattc ccatgacaaa gaataacatc cctttaaaac
     5101 agtatcttac ccaattttca ggtaagactt ttgatacaac cgtccccaat acccctccgc
     5161 atatagaagc aagaaaaata actggaacag gtgctaaatg atactgattt aaacctgtaa
     5221 ccacaacaat tgtagccaaa tgagacagct gggaaaagaa aataattgca agagaataca
     5281 tcgttgcttc ttttatcgaa atagaaaaaa acaccatcaa taaagataca ttgagcggac
     5341 caccaccaat ccctaaaaaa ctagaaatta agcccaatag aagaccacaa atcatataga
     5401 atcctatctt atcaaattga taagtttttt taaaatctgt taaaacaaat gatacaagta
     5461 gcatcacaaa tagtaaaatc atttgaacaa tggatactag ccgtactgat aattgagata
     5521 acaaaacttg aaaaataaga tgacctagaa atcctcctaa aacagaagaa aaggataccg
     5581 taaaaatcaa tctccatttt atctctttac tttgtgaaaa tcttttgatt gttgaaataa
     5641 tcgccattat aaaaacagag aaactagaat aaaaagcaat atcactgacc gaatggtatc
     5701 caaaactatc cataagtggc ttaattataa ttccaccacc catgcctgat atagaaccca
     5761 atccactagc tattataatg attagaaaat aaataatctc aaccactttt taagtccatc
     5821 ctattctttc aaacatctaa aacctagatg gctactagtg gaagtagaaa tacatccatt
     5881 tctagcagct actcggtatc gattacaata agaacaatga cataaaaagg aacctcctct
     5941 gatagcatac tcctcatctt gtatcccata ttttggcaac tcatagtcat cttcattaaa
     6001 actagctaat aaggtatatc tcggattgcg acaccattcc caaacattcc caatcatttg
     6061 atatagacca aaatcattag gtaaaaattc atagacagga gccgttccta taaatccatc
     6121 taaggcagta ttttcataag gaaatcttcc ttgccaagta ttggcatgat aatatccacc
     6181 ttctaaaaga gtatctcccc aaggatattc agattgtctt cctcctctag cagcatattc
     6241 ccactgtgct tcagtcggta aagacattcc gctccaatta cagaaagcca atgcatcttc
     6301 taaagcaaca tgaactactg gatggtcttc taaacccact agattactat tctcaccgta
     6361 gggatgtttc cagcaagcgt tcggaacttg taaccaccac ggagccccag caggatgagg
     6421 atatccctcc ctttctgcct ctggaacgaa caatataaaa acaaaagacc actcttgtcg
     6481 ctcagctagt gttttatagc ctgtttcttt cacaaattga gcaaattctt gattcgtaac
     6541 tggagtatcc gcaatggaaa aatcctttac actaacagcg acttgaggac cttcaaaatc
     6601 atctaaaaag ccctcttcag aatttgttcc catcataaat gtcccaccct tgattttttt
     6661 cattttcatg attgactatc ccccgttttc gttagagttg gcgttatttt agaaagttca
     6721 acaggaacta actcttcatc cacaacaaaa ccttcttctc tatatctaag aaagtctact
     6781 aattttttct tcatctgacg aacaataggt tgatattttt cacttggata caaatcattc
     6841 atttcatgcg gatctttttt catatcaaat aactgataat gatttaaaac aggaaaccag
     6901 ataaatttcc actggtctgt caaaatatat tgactagaat cttttcctaa agcatgttca
     6961 ccatgaaatt ctgttcgcca cccctcgtac tgtccaaata ataaattctt aacactccgt
     7021 ccatctagtt catctgtagt agttcctcct gccaaatcca cgagtgaagg aaaaatatct
     7081 tgaattttca ctaattgctt gattgttccc ctattaccag ctatcaatcc agccggatcg
     7141 taaataaacg aaggaatgtg gatacttccc tgataaggat atccctttct aaacagataa
     7201 tgttcaccaa gctgatctcc atgatccgaa acaaaccaga taatcgtatc tttatcatga
     7261 cgaaattctt ttagggcagt caaaaagcga ctaatttgat ggtctatatg agtaatcaat
     7321 ccaaaataag cagcaaccat tcttctttga tcatcttcct ttaatttccc tcttaaagca
     7381 taaatagacg gaatttgctt ttctaatact tcccaattcc cgatatgcaa atcgagaaat
     7441 tgaggcaagc gttccatata catatcaaaa tagtattttg ggggatttaa tggagcatgt
     7501 ggtttttcaa aagacatttt gagaaaaaaa ggaaccgttg gatctcttct ttgtaaaaat
     7561 gaaatggact cactcacaac ccagtttgtt ggatgtaact tctcatcttt atcccaaggt
     7621 ctagcttccc aagaattaca atccattccg tcatcaatca aatcaacatc ataaccaact
     7681 ttacccttta aaaaggctag atagtcacta gcataatcaa attgacttcc ataagcctta
     7741 tcatactttc tatcaacatg tagataccca tcgtgaagta agacatgatc aaacccaagt
     7801 ctctgtctgg aaggaaaaac atgcatctta ccaatacact ctgtttgata acccatatct
     7861 ttaaagactt ttggaagagt attagtaaaa ttccaaggca cctcatcttg ataaccaact
     7921 cgtccacttt tatcttggtc taagccagtc aataaagctg ccctagcagg aacgcaagaa
     7981 ggaactggag aataggcatt ttcaaaatta taacctacac tagccatcat atctaatgtt
     8041 ggagtgctaa ctagcttatc cttactattc aaggataagg cgtctgctct catttgatct
     8101 acaacaatca aaataatatt tggctgtttt gtctgaacca taaaatctcc tttctaatat
     8161 ggcaaaagag gcacaagaag atatctacct ttactgcacc cctttctata tcaatctctc
     8221 tatataaaac aataacattc ttgttatgtt ttatagaaaa atgaactaaa atatgactaa
     8281 atcgattagg aaattcaaat cattttctag tactgtttta gaagttacag tgtactattc
     8341 caacttcaat aaactataaa cctttgtcta ataacaattt tagtggagat aagaaatcct
     8401 acacctaact catcttacac gtaatctatt tctattttat cacaaaaaac gcaagtaaga
     8461 ccattaactc aattcagttt tatctgccat tttcacaaat gggaaataag tcaagacact
     8521 aataatcaaa caaacaactg ataagatgat ggcacgccaa tcaaatgctg tagagaagaa
     8581 accatataaa attggaggca ttacccaagt aacgttttgt gtaacaggtg aaacaagacc
     8641 ccagcttgtt gcccagtaag ctaccgttgc catgaaaacc gggctaagta caaatggtat
     8701 aaatagcaaa ggattcaaga caactggtaa accataattg accggctcac caatattaaa
     8761 cagaactggt gctagaccaa gtttagcaac ttttcgataa tgactgtttc ttgaaaaaat
     8821 taaaatagca agtactaatc ctaatcctcc aaaccagaca aacgccccaa aagacccact
     8881 tgtccatata taaggaatcg gttcaccttt ttggaaagca tccagattcg ctaacatagc
     8941 aactccaaac agcccttcca tgatgggagc caatacattt cctccatgga gaccaaaaaa
     9001 ccagaataac ttattcaaaa agatcatcag aataactgca aagaaacttt gagacaaacc
     9061 tagtaatggc gtttgtaaca ccttgtaaac ccaatcaatc aataagtcat tgctaagtaa
     9121 atggaaaaca taagtcaaga tggctactat atacatcgcc ataaatcctg gaatgataga
     9181 agtgaacggc ttagcaatcg cagggggaac tgaatctggt aacttgatta cccagttctt
     9241 tttcattact ttacagaaaa taatagaggc taaaaatcca atcatcatgg ctgtaaagta
     9301 gcctctggca ttaatatggt ttcctggaat cacattccca atagttacca tcagattttt
     9361 accatcaaat gctagattat caattccttg taagatttga tctaatttca catctcctac
     9421 atttgccaaa gggaaactct ttgtaactgt acttccaatc gaaatgacaa acgaagcaag
     9481 tgataccaaa ccagcagaaa ctgtatcaac cttgtaaatc ttagcgatat tcactcccaa
     9541 gcaatagatg aacaacaagg aaacaattgg tatacttccc ttgaatacca aattattgat
     9601 gtcaacaagc cactgaaagg ttttcgtaat actttctagg tgaaattgtt gtggtaaatc
     9661 cactagaaaa gcatttaata acaaagcaat ggaacctgtc ataataacag gcatagtccc
     9721 cacaaatgaa tcacgtaaag caactaaaaa cttctgattc ccaactttca ttgcaattgg
     9781 agaaagtttt tcttgcattt tatccaacat tgtattcata ccaaactcct aatttttttc
     9841 aaatcgttcg tatacttcta ccacttcttt cgccaagtca acaaaagtca gactcgtcat
     9901 taaatgatct tgcgcgtgta ccatcaagag gctaattgat gttttttccc cctgtgcctc
     9961 tcttgtcaac atttctgttt gagccttatg cgcctgtaat aaggcagcat tcgcatcagc
    10021 taatcttcga ttggctttag agaaatcccc tttttttgct gcctgaatag cctccatagc
    10081 attacttttg gcttccccac catacataat tagccccatt acagattcta aattactttc
    10141 atccataaca ttctcctcaa tcttagtcta ataaactttc agctaaatct aaaactttag
    10201 aaccattcat cattccgtaa tctgtcatcg gaataaccgc cacaggaatc tgtctatctt
    10261 ttagtttttc ttgaaagtcc cctagtaaat agcgaacttg aggacctaaa agcaacacat
    10321 ttacttcttt tgttgctaca atttcttctg cttcaggagc tggaactgca aaaatttctg
    10381 catccaaccc cttatcttct gctgcctttt gcatctttgt cactagcaga cttgtactca
    10441 tacctgctgc acatgctaac ataattgtta ctttagccat agcttactcc ttttatttta
    10501 ttgtcaatgt tactgttttt cgatcaactt tagactcata atctaaatgt ttgggacgac
    10561 tagtataatg caaattataa actcctggag gcatttgtga aatcttttct ttttcagttt
    10621 tattgcgaat taataaatct accgaagtat tccctccaaa gttattaaac ataggttcat
    10681 tttcaataga ataatctaac tcatatccac tattagttgt aattcctttt aataaatcag
    10741 gaacatctcc tctgtttatt actatatcct tagcgccatt tattttggga gattgactat
    10801 aatactcttc agcttgatgt tgttgtaaat catttctaga gtaagaaaca taatcaacta
    10861 caaattcagt ccctgataaa ttattgtcca ctaccccagg ccaacttcct cccatcgcta
    10921 aatttaactg aacatactga ggtctattaa aaatcttttt cgctatatta tctgatccat
    10981 aatatacttt tctaacaata tgattgtcaa ccatccatac aatataatct ttataccaat
    11041 caattgaaaa agtatgatac gaatcattaa agtttccact cgataattta aaggctgtac
    11101 cacgtcctgc aaattttcca tcatcattat ccgactgtcc ataatgaagc gtttgataaa
    11161 ctgtcttatt cccacttcca tttgaatttc gttcaccaac taattccatt atatctatct
    11221 cacctgttga cggccatcct cgtccctgaa caggattaat cttcccatca agtgtaaaat
    11281 ccgatccaag agtccagaaa gcaggaaaaa ctccttgacc tttcggtaat tttgcacgca
    11341 tctctaattt accataaaga aattctactt tcccatgtgt tctaacactt cctgaattat
    11401 atacaacctt tctgtgattg tttcttgggt taaaatactg atcttcctta gagcgattcg
    11461 tagctctaag aactaaattt cccgaacgta gaaaaacatt ctcatcactt cttacataat
    11521 gttgctgttc ccaaccacga attgatccta attcatatcc ccaatatttt ttatttaatt
    11581 gttcgccatc aaaatcatct ctccaaattt tcttatatga atttccttta gacagttgat
    11641 acatctctac attatcaata aaaatattag atttttttgt agtatcgtct tctgaccatt
    11701 tcactaattg aatcaaaact ttatcgtgtt taccggaatt gaaagaaaac atgtattttt
    11761 tccattcggt tgtattaact gtttgatcaa cagcttctcc aatgttattt tgaacaatct
    11821 ctccttgctt attattatca aaccatcttg cggtaaaata tccctctgct ccactaatat
    11881 ctactttggc aaaagcagat actaaataat cttcattagg ttctatatca ataacttgtc
    11941 caatatatcc atctgctcta ttatcattaa ttgcagtaga aggaatcata cctgagtaat
    12001 gtccgttact ataactctca tttgaattaa ttattcccct atttctagag ttccaaaaca
    12061 gctctccttg ctcaaaattt gaatttttta ttaaattttc attagcaaaa actttcgcat
    12121 gaataaatat taataaaaat aatataaata aacttaaaat taatttctta ttcttcattt
    12181 tatcacctat ttactgacct agccaagcga gatactgtat gtctcactcc tctaattgcc
    12241 ttgctcaatg cataaatatt atcgactgtt gccagtcccc catatcctgc gtcacctata
    12301 tgttgaatat caactccaca aattttattt ctaagtgcaa tttccttgat agtatctgta
    12361 tcagatgttt cttggctagt accaatagca ctcaatacaa gaccaccctt actatgaacg
    12421 agatcaacga cttcacgcaa ctcttggtca tgaaaggctg gaacggttcc aactgctgga
    12481 acaagtatca catccgcacc tgcttccaac aattgctctg cgacagaaag ctctgccaca
    12541 ggctcattca ctcctgcccc gtgcatttta ccagctataa tcaaacctga gaaattctct
    12601 ttagcagatt gaactgcttt gataatctct tgattgctaa ctcctgttcc aggatttcca
    12661 gtcaaacaga caaagtcaaa acctaactcc tctattcgat tcaatgtttc aacactagca
    12721 acacgacctg caacaatttc ctgtgtttcc tctagcatct ttgcagatgg gtcaatcggt
    12781 tccaaattta caccaattgg acaagcaaca agctggtgta agcgatgaat aacatcatca
    12841 cctgaactat ccaaagcata aattttaggc tcaaaaacat caacacaatt caataaaatc
    12901 atatcagctc caaaagctct agcaatttca gaattagtta tatccccaac aaatgtctca
    12961 cgagtaacta cattttcaga tagaacaact ctaccttcac ttgctaaaat actttgtttt
    13021 aattcttcag cattcatctg taatatctca gatggatttg cactaattaa acgtttcatt
    13081 ctcaatcctc caataactta aaccgttttt caatagctat tacaaatggt aaataaagta
    13141 agacatccaa aacaatcaat acaatttgta ataatgaacc agaaatactt cctgtagcaa
    13201 gtaaaccact tataacaggt ggcatagtcc aacctggatc tgtataagtt agcggaacca
    13261 aacctgatgc cattgctccc cacgctacta gtaagttaaa cattggagct aagataaatg
    13321 gaactagtaa caaaatgttc aaaacaatag gaacgccaaa cattgctggt tcatttatat
    13381 taaataatcc aggtataaca gttataggtg ccaaagtttt tagttgttta ctagctttct
    13441 tcttatgtgc taaatatcct aacgcaagaa ctaaacctat ggttgcacca ccgccaccta
    13501 tgaatacaaa attatccata aatacgctag taaaaatatt tggaagagtt tctccagttt
    13561 gataagctac tttatttgca tctagattag ctaaccataa cggtttcata actgcattaa
    13621 caacatttcc tccgtgtaat cctacaaacc aaaaactact attaaggaaa attaagataa
    13681 gaagaccaat aacattattt cctaaaagtc caagtggacc tcccaaagct acttgagcaa
    13741 tttcatgaag attaggtaaa cttaatttat ctaaagttgc ataaacaatc aaccaaccaa
    13801 caatagtcac tgcaccagga ataatggcac taaagctttt agatactgct ggtggaacac
    13861 catccggcat ttttatctgt atattatgat ttataaacca ttggtagata tagccattaa
    13921 tcaatcctaa aatcatagca acaaataaac cttttgatgc catgaaagcg gtaggcattc
    13981 ctgctccagc ctctcctcta atgaaaggcg taactgtaat aaaagatgat aatgacacaa
    14041 taccagcagg aataccatca actttgtatt gtctagccat aaagtaagcg ataccaaaac
    14101 tagctacaag accaagtaat ccaaaactac tatcaacacc cttccataaa tagtcagcaa
    14161 caccaatatc acccagatat ttttcccatc ctggaatagg aaaacttgca ataaccatta
    14221 gtaatgaacc tatcaacaat aaaggtatag ttagagtaat accgtctcga atagaaacca
    14281 acgctttatt attacccaat ctagccgcta ctggaagtaa cttttcttgt aataattttt
    14341 ccataacctt ttcctcttaa atatatttta ttatcaaaag ttatcaatta tctttatttt
    14401 ttgacgtcaa gttgttattt gattatcttt tgttatttat attttacaac tataagaaag
    14461 ccttgtcaag gatttgtgta aacatttgat tattttttat tatcaatata taataaaaag
    14521 agaccagtaa gtaatgaaaa gcttaaaaaa attaacatct acatttatcc atagcaaaaa
    14581 atcataggat tttaagaatc tgacaactag gaagaaaact aatatgacct tatctaagaa
    14641 acaattacaa ctaagagcta aaatactgga aacagtttac acattaggtc ccatttcacg
    14701 aattgaaatc gctactaaaa caggaataac acctgcaaca actagcagta tcacaaatga
    14761 tctgattaaa gaaaatattc tcttagaact tggtgaagac gaacacgata caagcgtagg
    14821 gagaaaaaaa atcctgctag acattcaagc taaacgattt tactacattg gttgtgaact
    14881 atctgaaaaa catttcactt ttgctttagg agataatcta ggaaatatct taaaggaaga
    14941 gaaagaaatt gttactaaac agttaatcca agaaaaggga aatcaactca ttaaccagac
    15001 actaaagcaa ttcttaaata actgctctga ttatgaaata gaagcaattg gaatcgcgct
    15061 acctggtcgc tatttagata attataaaat aacaacaaac aatcctttat ggcaacatat
    15121 cgacttagaa atgattcaat cccactttga taagcctttg tttttctcta acaatgttaa
    15181 ctgtatggct ataggtaaac gcctatttag tcgccaacag aatgacccta attttgctta
    15241 ttttcatttt gctagaggta tgcactgttc ttatatctac gacggaaaca tttatgggaa
    15301 aggaaatcta atgattggag aaatagggca tacagttgtt tcatctgagg gagaagaatg
    15361 tagctgcggg cgcaagggat gcttacaaac ttttgctgga gaatcttggt taatcaaaaa
    15421 atcaaaaatt ctatatcatc aatctcccta ttctctactt cctagtttag tcaaaaatgc
    15481 cgatgatatt gatatccaag ttattttaac tgcttatcaa ttaggtgaca ctggaataat
    15541 cacacttatc catcaagcct tactctatct tagtcaaacc attttaaata tcagtatgat
    15601 gattgactct caaaaaatct acctacatag tcctttacta acaaatcaac acatcatcca
    15661 aaaactatat agtgaaatga actacaaacc caaactgctc tataatcgcc tacctgaagt
    15721 cattattgaa ccttacaatg attttacagc cgcacactca gctattgcac tttgtttgta
    15781 tcatacaatt ctacattctt aattttctat tacatttaat aaataggcta aaaagaggga
    15841 gtatatcata aaaagcgaat aaacctgttt tctgaaaatc agaattctgt tttgttcgct
    15901 ttctttatat ttggaattat actcctatct cccctttttc ataatgtata gtaaaatgaa
    15961 ataataacag gacgaatcga tcgggacagt caaatcgatt tctaacaatg ttttagaagt
    16021 agaggtgtac tattctagtt tcaatctact atatttttgt acaggtgctt caaccatttg
    16081 aacgatttca aatccttctt tttggtaaag attctgagct ctttgatttg cctcgaagac
    16141 atttagagaa atactatcta tatcttcatt ttcaaaggcc aaactaacaa atttccttaa
    16201 agcctggcta cctaagtctt gctcctgttt ctgggggttg ataaaaaatc tcccgatatg
    16261 aagattgctg tcttctagcc tgattttctg gataagtccc acaaactctt gttcatcaaa
    16321 gattgaaaag actccttcca aggcttgaag ggtcagtaga aaaggaatcc ttggtcccat
    16381 ccattgttct tgaaaggatt tgcctaggga gttggaccac tggcatacaa attgagcgtt
    16441 ttctatactc accttttctt caaaacgaat tgtcatcttt tcctcaccat cttatctatg
    16501 tttctccatt atactatttc tcccattttt tacgaataga taagtatgat tgatttttat
    16561 ttttttctcg tcgggagcat tctcgcttcc tttcttggtt tggtcattga ccgttttcca
    16621 gagcaatcca ttatcagttc agccagtcac tgcgattcct gtcagactcg cttgcgtccc
    16681 ttagatttga ttccgattct ctcacaggtc ttcaatcgct ttcgctgtcg ctactgcaaa
    16741 gttcgctatc ctgtctggta tgccctcttt gaattagtct taggactcct ctttctgctt
    16801 tactcttggg aattgctttc cttggggcaa gtcgtcctaa tcaccgctgg tttgaccttg
    16861 ggtatctacg actttcacca tcaggaatat cccttactgg tctggatgac tttccaccta
    16921 atcctaatag cttcctctgg ctggaatctg gtcatggtct ccttccttgc tcttggaatt
    16981 ttggctcatt ttatcgatat ccgcatgggc gcaggggatt tcctcttttt agcttcttgt
    17041 gctctcgtct ttagcgtaac ggagttactg atcttgattc agtttgcttc tgcgacgggt
    17101 atcctggcct ttctcctgca aaagaaaaag gagagacttc ctttcgtgcc tttcctctta
    17161 cttgctgctt gtgggattat ttttggtaag ctactgcttg tctgataaaa tccaatttct
    17221 gccatatgtc cttcatgaaa ttatttcaca gttaaattat aaattatttc ttttgtacaa
    17281 agggatgatg ttatcaaatc gatctgttct tctatcttct tgatactgat caaaaaattt
    17341 catttcgact gaaaatattt cgcttataaa ctgtaaacga atactttgtt tagacattat
    17401 agtcgctaga ctgactagat gattactcaa aacgacgtcc agaatactct ttactttgct
    17461 tggtttttta acaaaaattt gatcatccaa aggttcaatc attttgtaac ctttttgcgc
    17521 aatttgacga taaaagtaag aatgttgctt tggagtcaat aatcctaact taaaagctcg
    17581 atactctaaa gcctgtatcg aaacattcaa atccgacttc aataaaatat aactatcagg
    17641 attgctgaca cgcttgccaa ccctctcttc aaatttgact aaaaactctt cttttggcaa
    17701 taaaaaacat gatgcaaaat aatttgcttc ttgctccaaa cgattgccat cttcattcat
    17761 atctttatat ttatgtaaaa gaatatgtcc tagctcatga gctaagtcaa aatttcgacg
    17821 tacagatgat ttattcgttc ccaacacaat ataaggtctt cccaattttg accatgcgct
    17881 ataagcatca gcttggccat taattaatcg ttccacgata tagatacctg aacgttctaa
    17941 tttataaagc aaatcatgat tatcttttga aatacctaat ttttccctgg cataaagagc
    18001 caattcctca atggattctc ccttatgata agattcactc actacattac ttaggtcatg
    18061 aattataata ttaggtataa ttacaaaact ttcaaaataa tcaatcaaac tatctacctt
    18121 atgtaaatac atagtttgaa tatctattgt tttccgtgtt gctaggtctg catttctaaa
    18181 ggcaattaca gaagaatcaa atcgaatgct ctcttcttcc tgttcaaaat aagttaaatc
    18241 aacatgaaat tggttggcca aatgcatttt ggttgataat ttaggtttcg tttcgttgga
    18301 ctcaaactgc caaatggctt gttccgttaa attaattctc tgagctaatt ctgctctact
    18361 taaaccattt aacagccgta attctttcaa tacccgacca ttaaacattt atatactcct
    18421 tactactttt gaccttcttg tttttctatt cttggaataa tttcaaaatc ttctgtttcc
    18481 gataattctg aaaaattagg aatatcttga tatttagctt cttcgaaatg gtacgaactt
    18541 gattgaatat actcagacaa atcttgaatc aagtgtagct gaccagttcg tgcatcaggc
    18601 ataacaacat ctacagatat aatattgttt tctgagtccg cctcataagt taaaatcata
    18661 aatttttcga tattcgaatt tttagtagct tgttcaattt cttgaatcat ttcatcagaa
    18721 actaactcca tctgaattgg aaaggaatga ctatcttcat catttttgta ggaagaatgt
    18781 tgattaagat aaagtgtatt catctgagcg tattcaaata agtagccact cttatttttt
    18841 tgtaccaaag gaaattggtt cgtaagtcgc ttcttaccct ttataattaa caatactttc
    18901 ccatattttt ctgtatttgt ttcaaattct aaatatcccc aagtctgtcc tgctaattgt
    18961 aatttatact caaacaaatc tgctgatgca aatgcagtat caatatgatt aggtcgcgtc
    19021 catgcataac cattcgacac tatcattgtc tctctttttt ctagacgttc atctacataa
    19081 tctttttgcc ctttcatcaa agtatctaca attttttgtg cctcaagcga atcaaagaga
    19141 tcctgattca acataattct tcctcctcca aatacttttt aatgaattat atcattttct
    19201 taaagaaatt actacaataa ttatcttttt cttaaagttc tgtgtcagag taatttagaa
    19261 aattatatct tctatagtaa aatcaattaa aaactgaaca aatttattgg gaaattcaaa
    19321 tcgctttctg aaaatatttt aggaaccgta gtgtaatatt ccagattcaa ttcactataa
    19381 aactgacctt tctcctgcaa aagaaaaagg aaagacttcc tttcgtgcct ttcctcttac
    19441 ttgctacttg tttgattatt tttggtaagc tactgcttgt ctgataaaat cctgaatcgg
    19501 ctctccttgg tggagagctt ttactatttt tgaaccgacg ataacaccat ctgacaccgc
    19561 attgaagcgt tccagatcgg cttgactaga tacaccaaaa cctgtcaaga ctgggatgtc
    19621 ggccacttga tgaagttgcg ccaagtgctt gtccaaatct gcacggtaat tgcctgattt
    19681 ccctgtcacc ccattgatgg caacggcata gacgaatccc tccgcgcctt caatcaactc
    19741 tttctggcgc tcaattcctg tggtcaagct tactaaagga atcaaggcga tatctgtatc
    19801 tgccaaaaat ggttctacaa agttggcatg ttcatgaggc aagtctggga taatcaagcc
    19861 cttcacagct gtatcagcca gatctttgac aaagttctcc acaccgtact gaaagagggg
    19921 gttgaagtag gtcatgatga ccagtggaat ctctgtttca atggttttca aggtttcaac
    19981 taaagcctgg gtagaggtcc cgtgggctaa actgcgcaag ccagcttctt cgataacagg
    20041 tccatctgca acagggtctg aaaagggaat acccacttca attgcagaga cacccaaatc
    20101 ttctagaaag tggattgttt ctcctagtcc atccaaacct ttctcgtggt ctccagccat
    20161 gatataggga acaaaaattc cttttccagc tgctttaata gcatttaatt tttttgttag
    20221 tgtcttaggc atgagcttct cccttctttg ctgcatctgc ttccaagcgg tctttgactt
    20281 gaaccacatc cttgtcccca cgacctgata ggcagacaat catagacttt tctggtccaa
    20341 gttctttggc caatttcacc gcaaaggcga tagcatggct agattccaaa gctgggataa
    20401 tcccttccac acgagacaag agttggaatc cttccaaagc ttcttcgtct gtcacaggga
    20461 catagctggc acgtttaata tcgtggtagt gagaatgctc tggaccgata ccaggatagt
    20521 ccaaacctgc tgagatagag aaggcttcaa gaatttgacc atgggcatct tggagcacat
    20581 ccatgaggga accgtgaagg acacctggac aacccttggt caaggtagct gcgtggtgct
    20641 ccgtatccac accaagtcca gccgcttcag ctccatacat ggctactgac tcatcttcta
    20701 caaagggatg gaagagaccg atggcattcg acccaccacc aacacaggct actagggcat
    20761 ctggcagatt ttgtcctgtc aagtcacggt actgttgttt agcctctcga ccaatgacac
    20821 tttggaagtc acgaacaatt tctggaaatg gatgaggccc caaggcagaa ccaagaatat
    20881 agtgggtatc atcgatatta gccacccatg aacgaagggc tgcattaacc gcatccttga
    20941 gcacgcgcga accatctgtc acggcctcga ccttagctcc caaaagctcc attcggaaga
    21001 cattgagggc ttggcgtttg acatcttcct cacccatgta gatggtacat tccatgttaa
    21061 agagggccgc agcagttgca gttgccacac cgtgctgacc agcacccgtt tctgcgataa
    21121 ttttcttttt acccatgcgt ttggcaagcc aaacttgtcc taaggcattg ttaatcttgt
    21181 gggctcctgt atggttaagg tcttcccgtt tgagataaat cttggctccg ccgatatgct
    21241 gggtcaagtt ttttgcgtaa taaagaggag tttcacgtcc tacgtactgg cgcaaaagct
    21301 ggtttaattc ctcttggaaa cttgggtctg cctgactttc acggtaggcc ttctccaact
    21361 ccaaaactgc tgtcatcaat gtttctggga caaaacgtcc gccgaatttt ccgtaaaatc
    21421 catctttatt tggttcctga tatgccatgc tttaccctct ctataaatct tctaatcttt
    21481 tcatgatctt tttgtccatc tgtctccact ccgctcgata catctactgc atagggagta
    21541 aaatattgaa ttgcttttac tacattatct tcattaaggc cacctgcgat aaagaagggc
    21601 tgtgctagtc cagtcgtatc cagttgaccc caatcaaagg gctggccact tcctgccaca
    21661 ggggcatcaa agagtagata atctgcctga gaattaggga catgcccatt tccatctacc
    21721 tgcacagcct gaatactggc acaaggcaaa ttctcaaata aatcatctgc cacctgaccg
    21781 tgaacttgaa ccaagtccaa gccaactttg tcaatcgctt ccagcagttc tacccgactt
    21841 ggtgaaacaa atactccaac ctttttcaca tctgcaggaa taagctttgc caactcagct
    21901 gcctcttcta aagtcacctg tcttttacta ggtgcaaaga caaaaccgat atagtcggct
    21961 cctgctgaaa cggctgtttc caccgcttct ttggtcgata gtccacaaat tttaaccttt
    22021 gtcaatctgc aactccttga ttctctgggc cacattttct gcctgcataa gagctgtccc
    22081 taccaaaatt ccgttaaagt atggggctag tcgttccgca tcctgccctg tgaaaatggc
    22141 agattcagaa atgtaatagc gaccttcctc aaagtaaggg gctaaatcta cactggtctg
    22201 caagtcgacc tcaaaggtag tcaagttgcg gttgttgacc ccgataatct cagcaccaag
    22261 tctgtgggct acctctagtt cagctagatt gtgagtctcc actaagactt ccagaccaag
    22321 ctctgtcgcg tagtcataca gttccttgag gcgttcttcg gacaaggctg ccacaataag
    22381 caagataact gtcgcacctg cattgcgagc gcggatgatt tgcttttcat ctatgataaa
    22441 gtctttgttg agcgtcggaa tctctacctg actggaaatt tcccgtagat aatccaaatg
    22501 ccctttaaag aaaacctcat ctgtcaacac cgaaatcatc actgctccgt tttcttcata
    22561 agtctgggcc tgttgcacaa tatccacatc gagattgata tctcccaaac tagggctagc
    22621 tttcttgacc tcagcgatta cctgcaagca gtcctgatga ttcttcaaaa attctgccaa
    22681 gcgataggtc tggcgcagag gctggatttg ctccagcttc atctgctcca cctcacgcgc
    22741 cttctgctct aagattcgtg ctaaaaattc ctgactcatt tttggtactc ctgtaacagt
    22801 ctgagttttt caagggcctt gcctctagca atcacttgac gggccaaggc aactccttcc
    22861 ttgatgctat caatcttacc attagcatag aaaccaagac cagcattcaa gactgtcgtt
    22921 tccaagaatg gacttgcttc gtttttcaga acgctaagca aaatttctgc attttcctga
    22981 gcattccctc cacgaatatc ttccatagca tagccttcca ttcccaaatc ctctggagta
    23041 aagcttgaca agctgatttc gccattttca agaagtgcaa tcttggttgt tccgttcaag
    23101 ccagcttcat ccaacccttc tggtccagca accacgatgg cacgtttgcg acccatattt
    23161 ttcaaaacct gagctgtact ttctaggagt tctggacgac taattccaag aagctgtgtt
    23221 tctaaagcca ttggatgaat cagtggacca gtcaagttca taatcgttgg aattcccaat
    23281 tccaaacgag ctggcatgat gtatttcata gctgggtgca tatttttagc gaagagaaag
    23341 acgatgccag ttttatcaaa gaccttacct agttcagctg gtttgaggtc aagattgatt
    23401 cccaaggctt cgaggacatc tgcggaacca gatttagaag aaatcgagcg gttaccatgc
    23461 ttggccatgt gaataccgcc accagccaag acaaaggctg cagttgtgga aatattaaaa
    23521 ctgaaagact tgtccccacc tgtaccacaa ttgtccatgg catcatgaat ctcagttgga
    23581 atatgctggg catgtcctct catgacttgg gcaatggctg tgcgttcttc aggtgtttcc
    23641 cccttcatct taagagctaa gaggagagaa gcaatctgcg cttcagttac acgcccagtt
    23701 atgatacgct caatgacatc cgtcatttcc acacctgata aattttcaaa ttttgctagt
    23761 ttttcaataa tctctttcat cctagtttcc tcactttaca acctcctcga taaaattccg
    23821 aatagaagac aagccgtctg gcgttccaat gctctctgga tggtactgga agccataaat
    23881 cggtaggttt ttatgttgaa tccccatgat ggtttggtca tcagtcgaac gagctgtcac
    23941 ttcaaagtct tctggcattt cctcaatcaa aatactgtga taacgcatga ccgcacgtcc
    24001 atcctcaata ccttgataca aaacagatgg cgcttcaaag ttgatattgc tctgtttccc
    24061 atgcatgact tttggagcca aacctagctt accaccaaag acttctgcaa tggcttggtg
    24121 gcccaaacaa atccctagaa tcggcttctt gcctgcaaaa tcacgaatca tgtcttccat
    24181 ctttccagca tcaactggcc aaccaggacc aggagaaaag accagaccat ctgctttttc
    24241 agcttcttca tacagcttgg aatcatcatt tctcagaacc tgaacttctg caaaattccc
    24301 aatgtattgg gccaagttat aggtaaaaga atcatagttg tcaatcaata aaatcatggt
    24361 cttagttctc caattctagt catagatttt gctttgttaa tggtttcttg gtattcgttt
    24421 tgggcgatag agtcgtagac aatccctgcc ccagcctgca cataggctct ttgatttttg
    24481 agaatcatgg ttcggatggc gatggccaaa tccatatcac ccgtcgcaga caagtagccg
    24541 attgccccag cgtatactcc ccgtttttcc gtttccagtt catagatacg tctcatcgct
    24601 cgaatctttg gcgctccaga aacggttcca gcaggaagcg ttgctttcaa ggcatccatg
    24661 gcagtgagtt ctgcaagcaa acgtcccttg accacactgg tcaaatgcat gacgtagcgg
    24721 aagagctcca cctccatata cttagtaact tggacactgg ccgtttcaga gatgcggcca
    24781 atatcgttac gccccaagtc taccaacatt cgatgttctg ctgtttcctt ctcatcagag
    24841 aggaggtcag tcgccaaggc cttgtcttct tcatccgtag cccctcttgg tcgcgtccct
    24901 gcaatcggat tggttgtcac gatgccattt ttgacagaaa ccaaactttc tggactagct
    24961 ccgatgattt gataatcccc aaaatcatag aaataaaggt aattagaagg attagttacg
    25021 cggagatttc tgtagaagtc aaatggattt ccagtaactt ctgctgagaa acgctggctg
    25081 agtacacatt ggaacatatc accattacga atcaagtcac gagctgtttc caccatttcc
    25141 tcaaacttct gaggagcgat atgcggtttg aagtctaacg gagatagatc caagtcttca
    25201 aactcatttg gagcaggaat gcgtaattcc tcaagcactt ggttcaaggc tttttccaat
    25261 tcttcttgac tacgctcact atagagagca tcctcgatga catgtatctt ctccttcttg
    25321 tggtcaaaga ccatatagct ctcatagaca aagaaatgca tgtctggcgt cccaattgta
    25381 tcctcaggga tttgaccaat ttcttcataa agcgaaatca tatcgtaacc cacaaaacca
    25441 atggctccac caccaaaagg gagctctgag tggtgctgac tcttatgaat cacttcataa
    25501 aggaaatcca agggatcccg atcaatcact tgaccatttt gatagagaac tccattttca
    25561 aacttaatct caaaaactgg attataggct aggatagaaa aacgagccgt ttccttgtct
    25621 ctcggaatac tctctaaaat aaccttatgt tgccccttta agcgcatata agccaagatt
    25681 ggtgataaga catctccatg aatgattcgt tccattgtaa tttccctttc agttctaatt
    25741 ctagttcgtg gcgactgtat gaaaaatccc cacgcaaaat aacttgcgtg aggacgaaat
    25801 tcgcggtgcc acctcaatta taggatttct cctatctctc attcctgtct cagatacctc
    25861 ctgtaacagg ctgtgcgata aagggcactc ccttgagaat gatgttttct tctctcgttt
    25921 cagatgaacc caactttaca gctttctctg cttgttttca gcaaccacaa gctctctgtg
    25981 agagaaaaga ctgtaatttt tccatctatt attttttagc ttctagtaat ctgcaatcgc
    26041 agctaggtcc ttgcctccac gaccagagac attgatgaag agatgttcat ctcggtacac
    26101 ctttatactc ttcgaaaatc tcttcaaacc gcgtcaacgt cgccttatcg taggtaacga
    26161 cggatagaaa aaagcccaca cacagaatat acttccgtgt gagggcgttg gtaacgcggt
    26221 gccacctcaa ttataaaggg actatccctt tacatctctg ccttgtttaa caacaagctg
    26281 cactgtaagg tgtgcgcacc gaattttcat tgtttcaaat tcattttcaa aatcagccca
    26341 ctttcactac ttccaaccac ctattcacaa tcaccacagg ctccctgaag atcaaaaata
    26401 gttacttttc tgatttgttg aacttatttt aatactttgt tttttctttg tcaagacttt
    26461 tttacgattt ttttgatatc attcgaatgt gaccatatct tccttagatc gaacatgaac
    26521 atgtcccact tgttagaaat tggatccaac tcaatagaaa ctgaatggag gctaaacaga
    26581 acttatttta gaacactcca tcttttccac taggattttc aagaattaaa caatactaga
    26641 aactctgtct cctaacaaat ttaggagaaa cttcaacaga tgtgacactt tcccctttaa
    26701 taattgctaa aacaccttct atcatttctt tagccaattt aacataattg ggagcaattg
    26761 tagacaaagc tggagtataa tactgagaaa taggaatatt atcaaatcca atgatagaaa
    26821 tatcatctgg aataagaatt cctttctcat agcacgcacg aatcaagccc tgaacctttt
    26881 catctcctga aacaaaaata atgtccggat aattttgggt agtcaagtgc tgcattgcat
    26941 aagaataaac tgaatcaatt gtagataagc cataaatgac ttttaaatcc ataaagtaat
    27001 ttttatcatt cagaaaagaa cgcacacctc tttcacgatc cttattaaca tgagattctc
    27061 ctcccataag caaccacata tttttaaatt tttcttcagt tacagctttc atcatatcat
    27121 aagtagcttg aaaattatta ttagatacat agactactcc agacgtttga gattcaccga
    27181 aaacaagaaa aggcatatgg ttcttcttta aatactgaat tctgatatca tctacacttt
    27241 cataaaaaac aataacacca tctactaggc tacctgtgct tgatataatt gaattactaa
    27301 ttgtatcctc ctctccaaag tactcaacta tagcattaac accaaattct ttacacgtcc
    27361 gtaacacttt atctaacagc gtatgaaacc aaattaaagg aaaagagtcg atttttttta
    27421 cagaaatcaa tatatttata gcttcttttt tagttaaatt ttttgcatac gcatttggaa
    27481 tatacgacaa ttcctctata actttttgaa tcgcttgata agtttcttct ttaacattta
    27541 ctccaccatt aataactcgt gaaactgttt ttggagaaaa acctgataaa cgtgcaatat
    27601 cataaatagt tacctttttc ccatttatat ttttcatttc agtcctccat tacgaacatt
    27661 ctaatattac tatacaatat ttaatttttt ttaacaagag aatttagtaa attatttaag
    27721 atccacaaat tcacaaaatt aattttacaa atattcttcc ccttcaaaaa agtttaaatt
    27781 gcatttcaca cctttatttt taagaatgtt tccaacttca cgacaaataa attcatatga
    27841 gaaaaaactg ccataaaatt gtagattaac tttttcagta aaatgtgtag gatttataaa
    27901 aacatataat agcctgtcaa tgtaacattt taacatagag ttaatttttt ctttaaagat
    27961 aacatttgtt atcaactcat caggaggtaa atgaaaggca aacaccattt cacaaatatc
    28021 ataaaaagaa ataaatttgt atacttgtat caaacaatta ttatcaaaat attctatttt
    28081 acctaaatca aaattgattt tataatcttt cataaaaacc tctgagcaaa aatctactca
    28141 aaaattagat gattaaaaca tctaaaaaac aaaaggacaa aaacatctgt ccctttgttt
    28201 actaaatttc agctaatttc ttcgacataa ataacaccta caatattagc aatttcttcc
    28261 atcagtcgaa gatgttcaaa tctacctgat aattccagag taataaatga cgctattttt
    28321 ttgtccggaa catcaaagta ttcaattctg tcagaattaa catctccaaa cgctgttctt
    28381 gaatcggtca ttctgatacc attttctgca caataaacca atacacgatt ataggcttct
    28441 gtagatttaa ctactatata caattcaatc attttagaac gattttgcag atattttttt
    28501 agtggttgga acatggatat cacaccccaa acagaaatgg ctactaaaag agctccctca
    28561 taaaaaccta ctccaatagc taatccaatt cctgccgaag cccaaatgcc tgctgcagtt
    28621 gtcagacctg taattttctt cttatctgta ataagaatcg ttccagcgcc tagaaaaccc
    28681 acacctgata taacttgagc tcctaatcgt gtaggatctc ctgtcccaaa tttataagat
    28741 acgtattcat tcgtcatcat aatcaaacat gcagctagac aaacaatact ataagttcgg
    28801 atgcctgcag gctgggattt gctccctctc tctaaaccaa ttatactacc aatgactact
    28861 gataaaacaa tcctgacaac tatttcaata tttgataacc caagactagt ggctgtcatg
    28921 attatttcct tactttacgc cccggtcttt gtgtgaagta taataccgtt ccagaaataa
    28981 tcatcagaac aattgtataa acaaatacca gagcttgtgc attagatgtt gctgtttcat
    29041 cacctgcaga tcgaatcgta atacctaatg gttgagctag gggatggtaa aggaatacag
    29101 ataagtcgaa gtcagttaat aaagagttaa agtttaaagc aataacagag agaacaaccg
    29161 gtaaaataaa tggaatgata accttcatca tagtataaaa aggtgaagca cccatacttc
    29221 ttgctgcatc ttccatctca tcatcaacac taaataaaat agcacgtacc attctataag
    29281 aaaatgggat ttttacaact atatatgcaa taagtagaat taccaaacta cctaccaaaa
    29341 tctgattcaa aacaagaaat tgtggctgat taaaagtaaa taataaactt actgctaaaa
    29401 gtgtacttgg tagtaaccaa ggaagtagag caccatattc aaataagaaa tcaaaacgag
    29461 atttatgttt tctgacaaca cgagcaaata caactgcgag aattgttgct gttgtcgcag
    29521 caataataga ataaataaag ctgaccaaga atggagagaa tgccgcacta ttactaaaga
    29581 ataagcgata attttctaaa gtaaagtttg ataatgttaa gttacctgtt tgaattgcaa
    29641 ctggatctgt aaatgagtat aatactataa aaattagtgg aagcatgaaa actgtgaaca
    29701 atccatatgc tacaatgtga gcaatgatat tccaaggctt agacgcaatt ttttgttttt
    29761 taagaggcgc tttagtctta gagatagaaa tataatttcc acctttttct atcttattca
    29821 tgatagtaag caaaattgta gttgcaatac ctaaaataat tgcaagtaag gcagctaaat
    29881 cacgagaatt ccccatccct gcaaatgtaa taatcattgg atttatagtt tgaaattctt
    29941 taccaccaac aatcatgggt gctgctactg cagataaacc actaagaaaa accataatag
    30001 taagtgcaaa tagagttgga attaaggttg gtaacactac ttttcggaaa acagtaaatg
    30061 gttttgctcc catatttcga gcagcctcaa tagtgtgata gtcaacgctt cgaattgtat
    30121 ttgttaaaaa caatgtatga ttagcagttc ctgaaaatgt cataatgaat aagactgcac
    30181 catacccaat aaaccagtta gagtctaaag aagggataac attttgtaaa aattttgtaa
    30241 tcaatccata aggaccatag acaaatttat atccagtcgc taaaaccact cctccataaa
    30301 ttaaagaggt catataacct aattttaaaa ttttagcacc tttaatatca aagtactctg
    30361 taaatagaac acaaagaata cctacgacat taactgtaat aatgagtgaa aatgctaact
    30421 taaaactgtt cataatactc tgaagtgccc tctgagattt tagaacacga tgtacagcat
    30481 caagggaaaa ttctcctcct tttacaaata cattcactac tagatcaaag tttggataaa
    30541 taataaatgt tactaagaac cagattaacc ctaaacgaat aagccaatct tttaaattta
    30601 atttatgacg catactgcac ctccttaaaa ttgcagaacg tctgatggtg tgataaataa
    30661 ttccacactt tctccgacag atctaatagc agcctgacta tcaatacttg ttacattaag
    30721 aatctgactt tcagaaactt ttattgtata gtgaattgta actccagaaa actcaacatc
    30781 aataattgtc ccttttagaa taaaatcttg ttcagtttca cgattgaatc gaactttctc
    30841 taatcgaatg tatccttttt tatcctctaa gaaaacgctt gtatttttca ataatacttc
    30901 gtggactgtt tcatcggtca aaacattaat atctccaata aaatcacata caaattcagt
    30961 ttgagaatta tgataaatct ctactggtgt accgacctgt tcgatgtatc cattgttaaa
    31021 gactgcaatt ctatcagata aagtcaaggc ttcctcttga tcatgagtaa catataaagt
    31081 agtaatacct aactcttttt gaagtctttt caactctttt ctcaaatcta cacgtaattt
    31141 tgcgtcaagg tttgacaatg gttcatctag acaaagaatt ttaggttcaa gaaccagagc
    31201 acgagccaat gctacccttt gttgttgacc cccagataat tctgatacat tacgctgtaa
    31261 ctgttgatca gagatcttaa tttttgctgc cactgctgat actttagctt taataacatc
    31321 tggagctacc ttcttaactt ttaaaccaaa tgcaatatta tcaaaaacag tcatagttgg
    31381 aaatagcgca taagattgaa atacaatacc aatcccacgc ttttcaggtt ccaaatgagt
    31441 gacatctgtt ccattaactt caatacttcc tgatgatgga tctaaaaaac ctaccaatgc
    31501 tctcaaagta gttgatttac cacatcctga aggcccaaga aatgtaaaga attccccttc
    31561 atgtatatct aaattcagat tatcaattgc aacaaaatca ccatatttaa tttgaatatt
    31621 atcaaattta atcatctcac taactccctc tattactaaa accaaaagcc tctctttatt
    31681 tcttccttaa atttagaaat aatagagaga cttggacata aaaaataact cttatttctt
    31741 attttacgta ttctaattca gctttttcta cccattcatc caaatgcttt ccaacagctt
    31801 cccagtcaat attttgtggt ttcacttgat caacaaattt tttcgtatct tcaggtaact
    31861 cttttagggc atctttattt gcaggaatag atccaaattt tttactatat tctacttgaa
    31921 tttctgattg accaaaccaa tcaataaatt ctttagctaa cgcttgtttt ttactagtgc
    31981 ttaaaaccat agtttgttca gttacaaatg gtacaccaat ctcaggagtc ataactttga
    32041 attcaacatt ttgttctttt tgtccgatta acgctccaga accccagatc ataccgtatt
    32101 gaattgggct ttctttatct aacgctttaa caactgagct ttcacctttt tgaagagtat
    32161 aggcatttgc aaagtattct tttgcaactt cccatccttt ttctgatacg cctaaatctc
    32221 ctttttcatc caggtaacga actaagatac ttgctagaat tgcccgtcct gtaccacctt
    32281 gaagaccata aattgaatat ttacctttat acttactacc taattcagtc caatctttag
    32341 gcatttcttt tacatcaggc gccccaatta aaactaatgg ttgaacaatc acaggattat
    32401 aataattatc tttatctgat aaagattgat caattttatc taaccattta ggcttgtact
    32461 gtactagtaa tttttgatct ctaattttat ttgagtcaac agcaccaatt ccaaatacca
    32521 tatctgcaac tgcattattc ttctcagcaa taacacggtc tgctaattga gcgccagcga
    32581 tatcaaccat ttttatatta aaaccagctt cttttgcttt agcagttaac caatcaccac
    32641 gaccatttga gactgagttc gaatagataa ctaattcttg acttttatca gctttttctt
    32701 cagatgaaga agcagtcgta gaatttgaac ctccagagca agcagcaagt gtagtaagag
    32761 caactcccgt tgcaagtaca gtagaccaaa ctttcatttt tttcatgata agttctcctt
    32821 ttttattatt ttatttaaat ttttcgtgat atggaacaaa ttgtctcata tcttcaaata
    32881 cagtatagtc aatacggttt acagtaatag ttggaatctt ctctaataaa atttcagtta
    32941 attctgctct gactttagta aactcttctt cctcctcttc ggttagagga atccgaagat
    33001 acccaattga aatatggaat tgatatctat catgattagg gaaacaaaca cctgcttttt
    33061 ctgagacata agtacgaatt tcttctaatc tctttgcaga agcttcatct gcaggttcaa
    33121 ctagtatgtt ttgttttccc atttcagtta tacgcatatg aatttcttca tccaacaatg
    33181 gaaaaatttc aagttgttta gcaaagtaat catgtatttc ctgtaaaggt gtatctagag
    33241 gaagattact gctccaaaac tccgtttcac gattttcatg gcacaacaat tcaattacag
    33301 tcatgtgaat agaattcctt ggagttaaag taaacttatc gataaatggt aattctctat
    33361 aacgtgattg aataatatca acaacttcca tcaaatcttg tttagtataa agatttgcta
    33421 caactgtatt cccagggaaa tgattaaatt ccccattttc tttgaactta atttttgtta
    33481 agtttttcat ataaagacct tcttttttat atttgacatc ggtgtcattg tgtttacatt
    33541 atacaatgaa accgtttcct ttgtcaagcg ctgtcaaaca ttttttttaa tttatctttc
    33601 attaaaaggt taagtaattt ttccaaaata cagcactcat atagacagta tcatcaatta
    33661 tagccattgg gattttttga ttgccaattc catgtatctc tacacatgtc ttcaatcgat
    33721 tttgttgtcc tccaatttaa ttccttatat gctttgtctg catttgcata ataagttgca
    33781 acgtctcctg aacgtcttgg aactatttta taaggaatag ggatcttatt aacactttca
    33841 aatatattta caagttgtaa tacactagtg ccttctcccg agcctaggtt atagatataa
    33901 acatctgttt tttcagatac tttttctaaa gcttttatat gtcctattgc taaatctact
    33961 acatggatat aatcacgcac accagtacca tcaagcgtat cataatcatt tccgaacaca
    34021 cttagctctg atagcttacc taccgctact tgtgcaatat aaggcatcaa gttgttagga
    34081 attcctgagg gatcttcccc aatcaaacca gactcatgag caccaattgg attgaaataa
    34141 cgaagcaacg caatactcca ttctgaatct gccacatgaa catcttttaa aatttgctca
    34201 agcatcactt tcgtataccc ataaggattt gtcgcacttg tttgcatcgt ctcaattaga
    34261 ggtgactgat tgttaattcc atatacagtc gcacttgaag aaaagacaat ctttttaaca
    34321 ttaaattctg acatcacttc aacaagtgcc aatgtactca taatattatt tttgtagtac
    34381 atcacaggct tttgcacgga ttctccgaca gctttataac ctgcaaaatg aattgcagca
    34441 tcaatcgatt cttgttcaaa tacctttctc aatgcttgtt tatcacaaac atctaattcg
    34501 taaaacacgg gacgtattcc tgtaattgct tcaatacggt ctagcaccaa tttgctagag
    34561 ttcgaaaggt tgtcgacaat gataacttcc tttcctaaat ttagtaattc tactacggta
    34621 tggctaccaa tataaccagc tccgcctgtt accaatattg ccatctgggt ttcctcctaa
    34681 ttaattccaa ccgacttaac aaatctcata aacgcttcat gcccagacgg tgtattctta
    34741 taaactcctg catcttccag aactctcgca aacacttgtc ctgcttcgtg ttgaactacg
    34801 ctattaacct cttctttatt aatgcgagga tatttttctt tcaattggtc ggcccattct
    34861 aaatgataat ccgcaattgc attatcctct cctaaaagat attttccaac ttcttctaac
    34921 tctggtttca aacgaggtgg taatatcgca agtcccatca cttcgattaa cccgatattt
    34981 tcctttttaa tatgttgtac atcttgatga ggatggaaaa caccatctgg gtattgttca
    35041 gtagtatgat tatctcttag aacaatatct aattcgtatc tcccgtccac tttacgagca
    35101 ataggagtca ccgtatggtg tgggacatct tcagtcatag caatgatgtc tacttctaaa
    35161 tctgaatatt ctctccactt atttagaatt ttagtagcta aatctaacaa gcgattttta
    35221 ttttcacttt gtaacctaat tactgacatt ggccatttta caataccagc attaacatcc
    35281 tcaaagtctt taaaacaaaa ttcactctca aattttgctt tttccattgg gaaaatatgt
    35341 ttccctccct ggtagtggtt atgactaaga atggagcctc ctgagatagg aagatcagaa
    35401 tttgaaccag caaaatatcc tggcaaaata tcaacaatct ccaataattg ttcaaatgtt
    35461 ttagaggtaa tagccattgg tacatgttga ctattcaaaa atatcgcatg ctcattaaag
    35521 tatgagtagg gagaatactg gaatccccat acttcgtcac caagtttcaa ccgaataatt
    35581 ctatgattcg aacgtgctgg ataatttatt cgcccctgat atccttcatt ttccatacat
    35641 agtaaacatt tgggataatt agttgctttt actaattttt cagcagcaat tgtttttgga
    35701 tctttttcgg gttttgacaa atttatcgta atctctagct ctccgtattt agttgatgct
    35761 cgaaactcaa tattcttagc aatagcagaa gttttaatat aatcactatc tttacttaac
    35821 ttataaaact cttcaactgc ttcttgaggt gatatatcat atgaactc
//
LOCUS       DAYYYC010000019        35053 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.019, whole genome shotgun sequence.
ACCESSION   DAYYYC010000019 DAYYYC010000000
VERSION     DAYYYC010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.019"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            90..959
                     /locus_tag="ACHBV5_000962"
     CDS             90..959
                     /locus_tag="ACHBV5_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HFM9966781.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGAISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFEMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            963..1919
                     /locus_tag="ACHBV5_000963"
     CDS             963..1919
                     /locus_tag="ACHBV5_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HFM9966782.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            1919..2683
                     /locus_tag="ACHBV5_000964"
     CDS             1919..2683
                     /locus_tag="ACHBV5_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966783.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKDKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            2683..3393
                     /locus_tag="ACHBV5_000965"
     CDS             2683..3393
                     /locus_tag="ACHBV5_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966784.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            3752..4408
                     /locus_tag="ACHBV5_000966"
     CDS             3752..4408
                     /locus_tag="ACHBV5_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFM9966785.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            4516..5611
                     /gene="prfB"
                     /locus_tag="ACHBV5_000967"
     CDS             join(4516..4587,4589..5611)
                     /gene="prfB"
                     /locus_tag="ACHBV5_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFM9966786.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            5629..6321
                     /gene="ftsE"
                     /locus_tag="ACHBV5_000968"
     CDS             5629..6321
                     /gene="ftsE"
                     /locus_tag="ACHBV5_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFM9966787.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            6314..7240
                     /gene="ftsX"
                     /locus_tag="ACHBV5_000969"
     CDS             6314..7240
                     /gene="ftsX"
                     /locus_tag="ACHBV5_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFM9966788.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            7526..9706
                     /locus_tag="ACHBV5_000970"
     CDS             7526..9706
                     /locus_tag="ACHBV5_000970"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFM9966789.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            9758..10573
                     /locus_tag="ACHBV5_000971"
     CDS             9758..10573
                     /locus_tag="ACHBV5_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFM9966790.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYNRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            10713..12056
                     /locus_tag="ACHBV5_000972"
     CDS             10713..12056
                     /locus_tag="ACHBV5_000972"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFM9966791.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLESNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDRNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            12433..13623
                     /gene="metK"
                     /locus_tag="ACHBV5_000973"
     CDS             12433..13623
                     /gene="metK"
                     /locus_tag="ACHBV5_000973"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFM9966792.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVINK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            14176..15111
                     /locus_tag="ACHBV5_000974"
     CDS             14176..15111
                     /locus_tag="ACHBV5_000974"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFM9966793.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            15145..16182
                     /gene="holA"
                     /locus_tag="ACHBV5_000975"
     CDS             15145..16182
                     /gene="holA"
                     /locus_tag="ACHBV5_000975"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFM9966794.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            16355..16960
                     /gene="sodA"
                     /locus_tag="ACHBV5_000976"
     CDS             16355..16960
                     /gene="sodA"
                     /locus_tag="ACHBV5_000976"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HFM9966795.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            17117..17647
                     /locus_tag="ACHBV5_000977"
     CDS             17117..17647
                     /locus_tag="ACHBV5_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFM9966796.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            17668..18753
                     /gene="rlmN"
                     /locus_tag="ACHBV5_000978"
     CDS             17668..18753
                     /gene="rlmN"
                     /locus_tag="ACHBV5_000978"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFM9966797.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFVCTINDDKGMAIGARHITISTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            18753..19235
                     /locus_tag="ACHBV5_000979"
     CDS             18753..19235
                     /locus_tag="ACHBV5_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFM9966798.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKVRN
                     "
     gene            19237..20778
                     /locus_tag="ACHBV5_000980"
     CDS             19237..20778
                     /locus_tag="ACHBV5_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFM9966799.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(20834..21637)
                     /locus_tag="ACHBV5_000981"
     CDS             complement(20834..21637)
                     /locus_tag="ACHBV5_000981"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFM9966800.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(21720..21941)
                     /locus_tag="ACHBV5_000982"
     CDS             complement(21720..21941)
                     /locus_tag="ACHBV5_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966801.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(22420..22617)
                     /locus_tag="ACHBV5_000983"
     CDS             complement(22420..22617)
                     /locus_tag="ACHBV5_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966802.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKRNMDLLADD
                     SLAGDIILLWRIQFGTFTTET"
     gene            22787..23059
                     /gene="rpsP"
                     /locus_tag="ACHBV5_000984"
     CDS             22787..23059
                     /gene="rpsP"
                     /locus_tag="ACHBV5_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFM9966803.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            23079..23318
                     /gene="kphA"
                     /locus_tag="ACHBV5_000985"
     CDS             23079..23318
                     /gene="kphA"
                     /locus_tag="ACHBV5_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HFM9966804.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            23506..23791
                     /locus_tag="ACHBV5_000986"
                     /pseudo
     CDS             23506..23791
                     /locus_tag="ACHBV5_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG nucleotide pyrophosphohydrolase
                     domain-containing protein"
     gene            23895..24683
                     /locus_tag="ACHBV5_000987"
     CDS             23895..24683
                     /locus_tag="ACHBV5_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFM9966805.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELLE"
     gene            24714..25232
                     /gene="rimM"
                     /locus_tag="ACHBV5_000988"
     CDS             24714..25232
                     /gene="rimM"
                     /locus_tag="ACHBV5_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFM9966806.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            25222..25941
                     /gene="trmD"
                     /locus_tag="ACHBV5_000989"
     CDS             25222..25941
                     /gene="trmD"
                     /locus_tag="ACHBV5_000989"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFM9966807.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            25953..26291
                     /locus_tag="ACHBV5_000990"
     CDS             25953..26291
                     /locus_tag="ACHBV5_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HFM9966808.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(26322..26642)
                     /locus_tag="ACHBV5_000991"
     CDS             complement(26322..26642)
                     /locus_tag="ACHBV5_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966809.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            26740..26955
                     /locus_tag="ACHBV5_000992"
     CDS             26740..26955
                     /locus_tag="ACHBV5_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HFM9966810.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(26952..27188)
                     /locus_tag="ACHBV5_000993"
     CDS             complement(26952..27188)
                     /locus_tag="ACHBV5_000993"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966811.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSSKHCFEVVDETDEVS
                     SKHCFEVVDETDEVSNHTYGKAKLTRFEEIFEEY"
     gene            complement(27251..27787)
                     /locus_tag="ACHBV5_000994"
     CDS             complement(27251..27787)
                     /locus_tag="ACHBV5_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFM9966812.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(27984..29330)
                     /gene="gor"
                     /locus_tag="ACHBV5_000995"
     CDS             complement(27984..29330)
                     /gene="gor"
                     /locus_tag="ACHBV5_000995"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFM9966813.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGLYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            29616..30815
                     /locus_tag="ACHBV5_000996"
     CDS             29616..30815
                     /locus_tag="ACHBV5_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HFM9966814.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            30799..31500
                     /locus_tag="ACHBV5_000997"
     CDS             30799..31500
                     /locus_tag="ACHBV5_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966815.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            31502..32761
                     /locus_tag="ACHBV5_000998"
     CDS             31502..32761
                     /locus_tag="ACHBV5_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9966816.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            32885..34882
                     /gene="metG"
                     /locus_tag="ACHBV5_000999"
     CDS             32885..34882
                     /gene="metG"
                     /locus_tag="ACHBV5_000999"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFM9966817.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLDKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
BASE COUNT        10625 a         6360 c         7683 g        10385 t
ORIGIN      
        1 tagtttgctc tttgattttc attgagtata agaacctatc aaaaagtgag ggaaaaccct
       61 cggaattata aatagaaaga gtgaatctta tgctccaaca actcgtaaat ggtttgattc
      121 taggtagtgt ttacgcgctg ttagccctag gatataccat ggtttacgga attatcaagc
      181 tcatcaactt cgcccatggt gatatttata tgatgggagc ctttatcggt tatttcttga
      241 tcaattcttt ccaaatgaat ttctttgtag cgcttattgt agctatgcta gcgacagcta
      301 ttcttggtgt cgtgattgag tttcttgctt accgaccttt gcgccactct actcgtattg
      361 ctgttttgat tacggctatt ggggtttctt tcctattgga gtatggaatg gtctatctgg
      421 ttggtgccaa tacccgtgcc ttccctcaag cgattcaaac agttcgatat gatttgggag
      481 caattagctt aacaaatgtg cagttaatga ttttggccat ttccttgatt ttgatgattt
      541 tgttacaagt cattgtccaa aagactaaga tggggaaagc catgcgtgca gtatcagtag
      601 atagcgacgc ggcacaattg atggggatca atgtaaaccg tacgattagc tttaccttcg
      661 ctttgggttc tgctcttgcg ggtgcggctg gtgttctgat tgctctttat tataactctc
      721 ttgagccttt gatgggggtt actccaggtc ttaaatcttt cgttgccgca gtacttggtg
      781 gtatcggaat tattcccggt gcggctcttg gtggctttgt gattggtcta ttggaaacct
      841 ttgcgacagc ctttgagatg tcagatttcc gtgatgccat tgtttatgga atcttgttgt
      901 tgatcttgat tgtccgccca gctggtatcc ttggtaagaa tgtgaaagag aaggtgtaaa
      961 cgatgaagga aaatttaaaa gttaatattc tatggttact ccttttgtta gctggctata
     1021 gcttgattag tgtactggtt tcagtcggag tacttaatct attctatgta cagattttac
     1081 aacaaattgg aattaatatt attttggctg ttggtctcaa cttaatcgtt ggtttttcag
     1141 gacaattttc acttggtcat gctggtttca tggcgattgg tgcctatgca gcagctatta
     1201 ttggttctaa atcaccaacc tacggtgcct tctttggagc tatgcttgta ggggctttgc
     1261 tttcaggagc agttgcctta cttgtcggca ttccaacctt gcgcttgaag ggggactatc
     1321 ttgcggtagc aactctgggt gtttctgaaa ttatccgtat ctttatcatc aatggtggaa
     1381 gtcttacaaa tggtgcggca ggtatcttag ggattcctaa ctttacaact tggcaaatgg
     1441 tttacttctt tgtcgtgatt acaaccattg caaccttgaa cttcttgcgt agcccaattg
     1501 gccgttcaac cctctctgtt cgtgaagatg aaatcgctgc tgagtcagtt ggggttaata
     1561 cgactaaaat taaaatcatc gcttttgtct ttggtgccat tactgcaagt attgctgggt
     1621 cacttcaggc aggatttatc gggtctgttg taccgaaaga ttacaccttc atcaactcaa
     1681 tcaacgtttt gattattgtt gtatttggtg gactcggttc cattacaggt gcgattgttt
     1741 cggctattgt tctgggaatt ttgaatatgc ttctccaaga tgttgctagt gtgcgtatga
     1801 ttatttacgc tttggccttg gtattggtaa tgattttcag accaggtgga ctccttggaa
     1861 cgtgggaact gagcctatca cgtttcttta aaaaatctaa gaaggaggaa caaaactaat
     1921 ggcattactt gaagtaaaac agttaaccaa acattttggt ggtctaacag ctgttggaga
     1981 tgtgactctt gaattgaacg aaggggaact ggttggatta atcggtccaa acggagctgg
     2041 gaaaaccacc cttttcaacc ttttgaccgg tgtttatgaa ccaagcgagg gaacagtaac
     2101 cctagatggt caccttttga atgggaaatc accttataag attgcctctt tgggacttgg
     2161 acgtactttc caaaatatcc gtctctttaa agatttaaca gttttagata atgttttgat
     2221 tgcttttgga aaccatcaca aacagcatgt ttttactagt ttcttacgct taccagcttt
     2281 ttacaagagt gaaaaagaat taaaggataa agctttggaa ttgttgaaaa tctttgattt
     2341 agatggtgat gcagagactc ttgctaaaaa tctttcctac ggacaacaac gtcgtttgga
     2401 aattgttcgt gcccttgcta cggaacctaa aattctcttc ttagatgaac cagcagcagg
     2461 tatgaaccca caggaaacag ccgaattgac tgagttaatt cgtcgtatca aagatgaatt
     2521 taagattaca atcatgttga ttgaacacga tatgaatctg gtcatggaag taacagaacg
     2581 tatctacgta cttgaatatg gccgtttaat tgctcaagga actccagacg aaattaagac
     2641 caataaacgc gttatcgaag cttatctagg aggtgaagcc taatgtctat gttaaaagtt
     2701 gaaaatcttt ctgtgcatta cggtatgatc caagcagtcc gtgatgtaag ctttgaagtt
     2761 aatgaaggag aagttgtttc ccttatcggt gccaacggtg caggtaagac aactattctt
     2821 cgcaccttgt caggtttggt tcgaccaagt tcaggaaaga ttgaattttt aggtcaagaa
     2881 atccaaaaaa tgccagctca gaaaatcgtg gcaggtggtc tttcacaagt tccagaagga
     2941 cgccacgtct ttcctggctt gactgttatg gaaaatcttg aaatgggagc tttcttaaag
     3001 aaaaatcgtg aagaaaatca agctaacttg aagaaggttt tctcacgctt tcctcgtctt
     3061 gaagaacgga agaaccaaga tgcagctact ctttcaggag gggaacaaca aatgcttgcc
     3121 atgggacgcg ctcttatgtc aacaccaaaa cttcttcttt tagatgaacc atcaatggga
     3181 cttgccccaa tcttcatcca agagattttt gatatcattc aagatattca gaagcaagga
     3241 acaaccgtcc tcttgattga acaaaatgcc aataaagcac ttgcaatctc tgaccgagga
     3301 tatgtattgg aaacaggaaa aatcgtccta tcaggaacag gaaaagaact cgcttcatca
     3361 gaagaagtca gaaaagcata tctaggtggc taaaacaatc cagtggattg ttttagtcgg
     3421 cagatgaaga ttacgaagta atcatcaata tagtccgggg gcccttttta gtcggtggat
     3481 gaagattgcg aagcaatcat caaatccaga ggattgtttt agccggtaga ttgagattgc
     3541 aaacaaatct gcatctacat tgaaagctga atttctaata attgaaaaaa tcgaatgaaa
     3601 cgtatcttac cttcattcag ggagctcgat tttagagctc tttttgctag cttattcata
     3661 cttttttgaa tttcgaaaaa gaaatgtaag cgtttgatag atttacaaaa agattgtata
     3721 atggggataa gaatagaaaa ggagaagtct catggcagtt aaagatttta tgacccgcaa
     3781 ggtagtttat attagtccag atacaacagt atctcatgca gcagatttga tgagagagca
     3841 agaattgcac cgcttgcctg ttatcgaaaa tgatcaattg gttggtttgg tgactgaggg
     3901 aaccattgca caagcaagtc catctaaagc aacaagtctt tctatctatg agatgaatta
     3961 tcttctgaat aagacaaaag taaaagatgt catgattcgc gatgttgtca ctgtctcagg
     4021 ctatgctagt ctagaagatg caacttatct gatgttgaaa aataagattg gtattctccc
     4081 tgtcgtagat aaccatcaag tatacggagt tattactgac cgtgacgttt tccaagcctt
     4141 tcttgaaatt gcaggttatg gcgaagaagg gattcgtgta cgctttgtta cagaagatga
     4201 agttggtgtt cttggaaaaa ttgtttcttt gattgtagaa gaaaatttga atatctccca
     4261 tacagtcaat attccgcgta aggatggtaa ggtcattatc gaagtgcaaa tcgatggatc
     4321 aattgattta ccagccttga aagaaaaatt tgaagcaaat ggtattcaag tggaagaaat
     4381 cgctcgcact tcagcaaaag tcttgtaaga agggaagccc aaaggcttct tttttcatga
     4441 aaaggggatt agagaaaaag atggaaagaa atgataaaat atgctataat gaaataatgt
     4501 aaaaaaggag tatttatgga catttcagta attcgtcaga aaattgacgc aaatcgtgaa
     4561 aaattagctt ctttcagggg gtctctttga cctcgaaggg ctagaggaag agattgccat
     4621 cttggaaaac aagatgacag aacctgattt ttggaacgat aatattgcgg cccaaaaaac
     4681 gtcgcaagaa ttaaatgaat taaaaaacac ttacaatacc ttccataaga tggaagagtt
     4741 gcaggatgaa gtcgaaattt tattggattt tttggctgaa gacgagtcag tgcatgatga
     4801 actggtagcg cagttagccg aacttgataa gataatgacc agctacgaga tgactctact
     4861 cttgtcagaa ccttatgacc acaacaatgc catcttggaa atccatccag gttctggtgg
     4921 tactgaggcg caggactggg gtgatatgtt gcttcgtatg tatactcgtt atggtaatgc
     4981 taaaggcttt aaagtggaag tgttggatta ccaagcaggt gatgaggctg gtattaagtc
     5041 ggtaacttta tcatttgaag ggcctaatgc ctatggtctc ctcaagtcag aaatgggtgt
     5101 tcaccgctta gtgcgaatct caccatttga ctctgccaaa cgtcgccata cctctttcac
     5161 atctgtagaa gtgatgccag aattggatga tactattgaa gtggaaatcc gtgaagatga
     5221 tatcaagatg gataccttcc gttcaggtgg tgccggtgga caaaacgtca ataaggtttc
     5281 aacaggtgta cgtttaaccc acattccaac tggaattgtt gtccaatcaa cagtggatcg
     5341 tacccagtat ggaaatagag atcgtgccat gaagatgttg caggctaagc tctatcaaat
     5401 ggagcaagat aagaaggctg cggaggtaga ttctctcaaa ggtgagaaaa aggagatcac
     5461 ttggggaagc caaatccgtt cttatgtctt cacgccttat actatggtaa aagatcaccg
     5521 aactagcttt gaggttgctc aggtagataa ggttatggat ggggacctag atggttttat
     5581 cgatgcttat ctcaagtggc gaattagcta agatagaaag gaactcacat gtcaattatt
     5641 gaaatgagag atgtcgttaa aaaatacgac aacggaacaa ctgctctacg cggtgtttcg
     5701 gttagcgttc aaccggggga atttgcttac atcgtaggac cttcaggagc agggaagtca
     5761 acttttattc gttctctgta tcgtgaagta aaaatcgata aaggaagcct atcagttgct
     5821 ggttttaatc tggttaagat caaaaagaaa gatgtcccgc ttctacgtcg tagtgttggg
     5881 gttgtcttcc aggattataa actgttacca aagaaaactg tctatgaaaa tattgcttac
     5941 gctatggaag taatcgggga aaatcgccgt aatatcaaaa gacgagtgat ggaagttttg
     6001 gacttggttg gattgaagca taaggttcgt tcttttccaa atgaactctc aggtggggag
     6061 caacagcgaa ttgcgattgc gcgtgcaatt gtaaataatc ccaaagtatt gatagctgat
     6121 gagccaacag gaaatctgga tccggataat tcatgggaaa ttatgaatct cttggaacgg
     6181 attaacctac aaggaacaac tattttgatg gcgactcata atagccagat tgtaaatacc
     6241 ttgcgccacc gtgtcattgc cattgaaaat ggccgtgtcg ttcgtgacga atcaaaagga
     6301 gagtatggat acgatgatta gtagattttt tcgccattta tttgaagcct taaaaagttt
     6361 gaaacgaaat ggttggatga cagtagctgc tgtcagttca gtcatgatta ctttgacctt
     6421 ggtggcaata tttgcatctg ttattttcaa tacagcgaaa ctagctacag atattgaaaa
     6481 taatgtccgt gtagtagttt atatccgaaa ggatgtggaa gataatagtc agacaattga
     6541 aaaagaaggt caaactgtta caaataatga ctaccacaag gtatatgatt ctttgaagaa
     6601 catgtctacg gttaaaagtg ttaccttttc aagtaaagaa gaacaatatg aaaaattaac
     6661 cgagataatg ggagataact ggaaaatctt tgaaggagat gccaatcctc tctatgatgc
     6721 ctatattgta gaggcaaaca ctccaaatga tgtaaaaact atagccgaag atgctaaaaa
     6781 aattgaaggt gtctctgagg ttcaagatgg cggtgccaat acagaaagac tcttcaagtt
     6841 agcttcattt atccgtgttt ggggactagg gattgctgct ttgttaattt ttatcgcagt
     6901 ttttttgatt tcaaatacca ttcgtattac cattatttcc cgcagtcgcg aaattcaaat
     6961 catgcgcttg gtcggagcta aaaacagtta tatccgtgga ccgttcttgt tagaaggagc
     7021 ctttatcggt ttattgggag ctatcgcacc atctgttttg gtctttattg tttatcaaat
     7081 tgtttatcaa tctgtcaaca aatcgttggt agggcaaaat ctatccatga ttagtccaga
     7141 tttatttagt ccgttgatga ttgccctact atttgtgatt ggggttttca ttggttcatt
     7201 gggatcagga atatccatgc gccgattctt gaagatttag gtaaaatagc tgcttttatg
     7261 aggagattgt aaaatctcct tttttgctac aagagttttt gaaaagagat gcgcagaaga
     7321 aaagagcttc caaagaagtc ccccagagaa gacttcttga tggctaattt gaacttgaaa
     7381 tttgactcac tagaaatttt ttagaaaaaa gtgtaatttt tttataaaag cctttacaaa
     7441 aaaaattaaa gtggtataat taaattatag aaggtgcaaa cgttttcgta aaacgtttgc
     7501 ctaaataaaa ataaaggaga tttgaatgat gaaagataca ttcaaaaatg tcttgtcttt
     7561 cgaattttgg caaaaattcg gtaaggcttt gatggtagtt atcgcggtta tgccggctgc
     7621 tggtttgatg atttcaatcg gtaagtctat cgtgatgatt aacccaacct ttacaccact
     7681 tgtcatcaca ggtggaattc ttgagcaaat cggttggggg gttatcggta accttcacat
     7741 tttgtttgcc ctagccattg gaggaagctg ggctaaagaa cgtgctggtg gtgctttcgc
     7801 cgctggtctt gccttcattt tgattaaccg tatcactggt acaatttttg gtgtatcagg
     7861 cgatatgttg aaaaatccag atgctatggt aactactttc tttggtggtt caatcaaagt
     7921 tgctgattac tttatcagtg ttcttgaagc tccagccttg aacatggggg tattcgtagg
     7981 gattatctca ggttttgtag gggcaactgc ttacaacaaa tactacaact tccgtaaact
     8041 tcctgatgca ctttcattct tcaacgggaa acgtttcgta ccatttgtag ttattcttcg
     8101 ttcagcaatc gctgcaattc tacttgctgc tttctggcca gtagttcaaa caggtatcaa
     8161 taacttcggt atctggattg ccaactcaca agaaactgct ccaattcttg caccattctt
     8221 gtatggtact ttggaacgtt tgctcttgcc atttggtctt caccacatgt tgactatccc
     8281 aatgaactac acagctcttg gtggtactta tgacatttta actggtgcag ctaaaggtac
     8341 tcaagtattc ggtcaagacc cactatggct tgcatgggta acagaccttg taaaccttaa
     8401 aggtactgat gctagtcaat atcaacactt gttagataca gtacatccag ctcgtttcaa
     8461 agttggacaa atgatcggtt cattcggtat cttgatgggt gtgattgttg ctatctaccg
     8521 taatgttgat gctgacaaga aacataaata caaaggtatg atgattgcaa cagctcttgc
     8581 aacattcttg acaggggtta ctgaaccaat cgaatacatg ttcatgttca tcgcaacacc
     8641 tatgtatctt gtttactcac ttgttcaagg tgctgccttc gctatggctg acgtcgtaaa
     8701 cctacgtatg cactcattcg gttcaatcga gttcttgact cgtacaccta ttgcaatcag
     8761 tgctggtatt ggtatggata tcgttaactt cgtttgggta actgttctct ttgctgtaat
     8821 catgtacttt atcgcaaact tcatgattca aaaattcaac tacgcaactc cagggcgcaa
     8881 cggaaactac gaaactgctg aaggttcaga agaaaccagc agcgaagtga aagttgcagc
     8941 aggctctcaa gctgtaaaca ttatcaacct tcttggtgga cgtgtaaaca tcgttgatgt
     9001 tgatgcatgt atgactcgtc ttcgtgtaac tgttaaagat gcagataaag taggaaatgc
     9061 agagcaatgg aaagcagaag gagctatggg tcttgtgatg aaaggacaag gggttcaagc
     9121 tatctacggt ccaaaagctg acattttgaa atctgatatc caagatatcc ttgattcagg
     9181 tgaaatcatt cctgaaactc ttccaagcca aatgactgaa gcacaacaaa acactgttca
     9241 cttcaaagat cttactgagg aagtttactc agtagcagac ggtcaagttg ttggtttgga
     9301 acaagtaaag gatccagtat ttgctcaaaa aatgatgggt gatggatttg cagtagaacc
     9361 tgcaaatgga aacattgtat ctccagtttc aggtactgtg tcaagcatct tcccaacaaa
     9421 acatgctttt ggtattgtga cggaagcagg tcttgaagta ttggttcaca ttggtttgga
     9481 cacagtaagt cttgaaggta aaccatttac agttcatgtt gctgaaggac aaaaagttgc
     9541 agcaggagat ctccttgtca cagctgactt ggatgctatc cgtgcagcag gacgtgaaac
     9601 ttcaacagta gttgtcttca caaatggtga tgcaattaaa tcagttaaat tagaaaaaac
     9661 aggttctctt gcagctaaaa cagcagttgc taaagtagaa ttgtaatata cttgaggttg
     9721 gaagctgtat tccaacctct tattttggga gaaaagaatg aaatttttaa cactcaatac
     9781 tcacagttgg atggagaaag aagcagagga aaaattccag attttgcttg aagatattct
     9841 tgaaaaggac tatgatttga tttgtttcca agaaatcaat caggagatga cctcgtcaga
     9901 ggtggaggtt aatgaccttt atcaagcttt gccagcagct gagcctattc accaagacca
     9961 ttatgttaga ctcttggttg aaaagttgtt agagcaaggg aaaaattact actggacctg
    10021 ggcttataac catatcggct ataaccgcta ccacgaaggt gtggctatct tgtctaaaac
    10081 acctattgaa gccagagaaa ttttggtttc agatgtggat gatccaacag actatcatac
    10141 tcgccgtgtt gccctagctg aaactgtagt cgatggcaag gagctagcag ttgccagtgt
    10201 tcatctctct tggtgggata aaggtttcca agaagaatgg gcacgatttg aggctgtctt
    10261 gaaaaaattg aacaagccac ttttactagc tggagatttt aacaacccag caggtcagga
    10321 aggttaccaa gctattttag ctagtccatt aggcttacaa gacgcatttg aagttgctca
    10381 agagaaaagt ggtagctata ctgttccgcc tgaaattgat ggctggaaag ggaacactga
    10441 accccttcga atcgattatg tctttactac caaagagtta gcggtggaaa atttacatgt
    10501 cgtatttgat ggtaacaaga gtccacaagt gagtgatcac tatggcttga atgctatgtt
    10561 aaactggaaa taataactga aaagaggttg gaactataaa attccagcct tttcttacta
    10621 gagaagctac tggaaatagc ctaaataagt gagactactg taatggaata aaatatggta
    10681 taattgataa gatagataga atcgaggatg ttatgtcatt tacgaaattt caatttaaaa
    10741 actatattag agaagccttg gaggagttaa aatttacaac tccaacagag gtgcaagaca
    10801 agttgattcc tattgttttg gcaggtcgtg acctagtagg agaatcaaaa acaggttcag
    10861 gtaagactca tactttcttg ttaccgattt tccagcaatt agatgaagct agcgatagtg
    10921 tacaagcagt gattactgca ccgagtcgtg agttggctac tcaaatttac caagtagcgc
    10981 gtcagatttc agctcactca gatgtcgaag ttcgtgtggt taattatgtg ggtggtacgg
    11041 ataaggctcg ccagattgag aaattggaaa gcaatcagcc tcatattgtt attggaacac
    11101 caggccgtat ctacgacttg gttaaatctg gtgatttagc tattcataaa gccaagacat
    11161 ttgttgttga tgaagcagat atgaccttgg atatgggatt cttggaaatt gttgataaga
    11221 ttgctggcag tcttccaaaa gacttgcaat tcatggtctt ctcagcgact atcccacaaa
    11281 aactgcaacc attcttgaaa aaatacttat caaatcctgt tatggagaaa attaagacta
    11341 aaacggttat ttctgacacc attgataatt ggttgatttc gaccaaggga catgatagga
    11401 atgctcaaat ttaccaattg actcagttga tgcagccgta tttggcaatg atttttgtta
    11461 acactaaaac gcgtgctgat gaattgcatt catatctgac tgctcaaggc ttgaaggttg
    11521 caaaaatcca tggagatatt gcccctcgtg aacgcaagcg aatcatgaat caggtgcaaa
    11581 atctggattt tgagtatatt gtcgcaacag atttagcagc gcgtgggatt gacattgaag
    11641 gtgtcagcca tgtcatcaat gatgccattc cgcaagactt atcttttttt gttcaccgtg
    11701 ttggtcgtac tggacgaaat ggcctaccag gtacagctat taccctttat cagccaagtg
    11761 atgactcgga tatccgtgag ttggagaaat tgggaatcaa gtttagtcct aagatggtca
    11821 aagatgggga atttcaagat acctatgacc gtgatcgtcg tgccaaccgt gagaaaaaac
    11881 aagataaact tgatatcgaa atgattggtt tggttaaaaa gaaaaagaaa aaagtcaaac
    11941 cgggttataa gaagaaaatt caatgggcgg ttgatgaaaa gcgccgtaaa actaagcgtg
    12001 ctgaaaatcg cgctcgcggt cgtgcagagc gtaaagctaa acgccaaaca ttttaataga
    12061 aattgttgga gtactgagct ccaacttttt tatttatgag aacgaactat ctaaaccgaa
    12121 acactacatt aaagactgca aattgcgatt aaaaatggta taatgataaa gttatatagt
    12181 cccgataaga tggtaggtat ttattacgaa gagttttcct atcagtagtt tgcaattcgc
    12241 aaagaatgac ggcttcgagg ttgctcgtct ttctacggtt gccgccatac tgcggtcacc
    12301 ctatgcgcct tactagcttc agaaataaaa aagtatcgtt tttatttctg aagctagtaa
    12361 ctcttagata atggaaattc ctatcagtac tttgtaactc tataacaata ttttttaagg
    12421 ggggacattt ttatgtcaga acgtaaatta ttcacgtctg aatctgtatc tgaggggcat
    12481 ccggataaga ttgcagacca aatttcagat gcgattttgg atgctatttt agcaaaggat
    12541 ccagaggcgc acgttgctgc tgaaacagct gtatatactg gttctgtcca cgtttttggt
    12601 gaaatttcta caaatgccta tgtggatatt aaccgtgtgg ttcgtgatac cattgcagag
    12661 attggttata ccaatacaga atatggattt tctgctgaga cggtgggagt acacccatct
    12721 ttggtggaac aatctcctga catcgctcaa ggtgttaacg aagccttgga ggttcgtgga
    12781 aatgctgatc aagatccact ggacttgatt ggagcaggtg accaagggct catgtttgga
    12841 tttgcagtag atgaaacaga agagctcatg ccattgccaa ttgcactcag tcataaattg
    12901 gttcgtcgtc tggcagaact tcgtaagtct ggagaaatta gctatctccg tccagatgca
    12961 aaatcacaag ttacagttga gtacgatgaa aatgaccgtc cggtacgtgt agatacagtc
    13021 gttatttcta ctcagcatga tccagaggcc actaatgaac aaatccatca agatgtgatt
    13081 aacaaggtca tcaaagaagt tattccatct tcttatcttg atgataagac aaaattcttt
    13141 atcaatccga caggtcgttt tgtaatcggt ggtcctcaag gggactcagg tttgactggt
    13201 cgtaagatta ttgtagatac ttatggtggc tactctcgtc atggtggtgg tgccttctct
    13261 ggtaaagatg cgactaaggt ggatcgttca gcctcttatg cggctcgcta tattgccaag
    13321 aatatcgttg cagcaggcct tgctaagaag gcagaagtgc agttggccta tgctatcggt
    13381 gttgcgcaac ctgtttctgt tcgtatcgat actttcggta caggaacagt agctgaaagt
    13441 caacttgaaa aagcggctcg tcaaatcttt gaccttcgcc ctgcagggat tatccaaatg
    13501 ctggacctca agcgtccaat ttaccgtcaa acatcggctt acggtcacat gggacgtaca
    13561 gatattgatc ttccatggga acgtttggat aaggtagatg ctttgaaaga agcagtaaaa
    13621 taagatttta agaggggaac gtcctctctt ttttatagtt tttaactata ctgggatact
    13681 gttctgaaaa tccattttgc gaaagtagag atttacatgt atagtagatt gaaactagaa
    13741 tagtacacct caacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttc
    13801 tcctgttctt gtttcatttt actatatttc tttaaaaatg ataaaggttg agatttctcc
    13861 tcgtaataga taatcatggg gatatttcaa tccaaagttt tattcgttat cacttgacta
    13921 ttgcaaggtt ttctagagca acagagtcat ggaatggact catggttgag atttctcctt
    13981 gttgcttgga cttcattcaa aagtctgtta cccaagcctt gttcaaactt ccaatacact
    14041 agctgtttcc atagcatgac ttctgtacta gactttcttt tccgaataaa tagatagaac
    14101 cacagaatct agtaaaccta gaattaaaat tatggtataa tattagcaat aaaagaaatc
    14161 tggaggatta gaatcatggt atcaacgaaa acacaaattg ctggttttga gtttgacaat
    14221 tgcttgatga atgcagcagg tgtggcttgt atgacgatag aggagttaga agaggtcaaa
    14281 aactcagcgg caggaacctt tgttactaag acagcgacct tggacttccg tcaggggaat
    14341 cctgagccac gctaccaaga tgttccactt ggttccatca actctatggg cttgccaaat
    14401 aatggcttag actattattt ggattatctt ttagatttgc aggaaaaaga gtcgaaccga
    14461 actttcttct tatctctggt cggcatgtct ccagaggaaa cccatactat tttgaaaaaa
    14521 gtccaagaga gtgattttcg tggtctgact gagctaaatc tttcctgtcc aaatgttcca
    14581 ggtaaacctc agattgccta tgattttgag acaacagacc ggattttggc agaagtgttt
    14641 gcttacttca ccaaacctct tggaattaaa ttgccacctt attttgatat tgttcacttt
    14701 gaccaagcgg cagctatttt caacaaatat ccgctcaagt ttgtcaactg cgttaactct
    14761 atcggaaacg gcctctatat agaagacgaa tctgtcgtta ttcggcctaa gaatggtttt
    14821 ggtggaattg gtggagaata catcaaaccg actgctctag ccaatgttca cgccttttat
    14881 caacgtttaa atcctcaaat ccaaattatc ggaacaggtg gcgttctgac tggtcgagat
    14941 gcctttgaac acatcctctg tggagcaagt atggtgcagg tgggaacgac ccttcacaaa
    15001 gaaggcgtca gtgcttttga ccgcattacc aatgaactga aagcaatcat ggtggaaaaa
    15061 ggctacgaga gcttagaaga tttccgtggg aaattgcgct atattgacta aattaaatcg
    15121 aaaaatcaga agaaagaagg gacgatgcta gccattgaag aaagtcagaa gttgacttta
    15181 tcaaatttac cgagcctgag cctatttaca gggacagatc agggtcagtt tgaagtgatg
    15241 aagagtcaaa tgttgaaaca gattgggtat gattctgctg acctcaactt tgcctacttt
    15301 gatatgaaag aagtagttta caaggatgtg gaactggagt tggtcagcct tcctttcttt
    15361 gcggatgaga aaatcgtgat attagattat tttatggata tcacgactgc taagaaacgc
    15421 tttttgacag atgatgagct taagtcattt gaggaatacc ttgacaatcc ttctccaaca
    15481 accaagttga taatctttgc agaaggaaag ctggatagca aaagacggtt agtcaaatta
    15541 cttaagcgtg atgccaaggt cttcgatgca gtagaagtaa aagaacaaga attgcgccag
    15601 tatttccaaa agtggagtca gaaacaaggt ctgcagttta ccaatcattc ttttgaaaat
    15661 ctcctcatca agtcggggtt tcaatttagc gaaatccaga aaaatcttct ctttttacag
    15721 tcctataagg cgaattctgt tatcgaggaa gaggatattg ttaacgcaat tcccaagacc
    15781 ttgcaggaca atatttttga tttaactcag tttattctga ctaaaaagat ggatcaggcg
    15841 cgcgatttag tgagagactt gaccttgcaa ggggaagatg aaatcaaact gattgcagtc
    15901 atgctgggac aatttcggac ttttactcag gtgaagattt tggcggagtc tggccaaaca
    15961 gaatcgcaga ttgcaagtag tttaggtagt tatctgggac gtaacccaaa tccttatcaa
    16021 atcaagtttg cattaagaga ttcgagagga ctttctttga gctttctgaa gcaagctatt
    16081 tcctatttga ttgagacaga ctatcagatt aagacaggtc tttatgaaaa aggtttcctt
    16141 tttgaaaagg cactcttaca gattgctagt caggtcaatt gacatttgtt gaaactacaa
    16201 cccgcgtcag gattatcttg tcgtgggttt cttgctgatt tgcttatttt attagaaagt
    16261 atatcagtga tttccttatc tataagcaaa aaacttgaaa aaagtgaatg tttgcgttat
    16321 cattttcata tagaaagaaa aagaggtatt acagatggct attatcttac cagaacttcc
    16381 atatgcatac gacgctttgg aaccatacat cgatgcggaa acaatgcatt tgcaccatga
    16441 caaacaccat caaacttatg tcaacaatgc caatgcagct ttagaaaaac accctgaaat
    16501 cggtgaagac cttgaagcct tgcttgctga tgtagaatct atcccagctg atatccgtca
    16561 agcacttatc aacaatggtg gcggacactt gaaccacgct cttttctggg aattgatgac
    16621 tcccgagaaa acagctcctt cagcagaact ggcagcagca atcgatgcaa catttggttc
    16681 atttgaagaa ttccaagcag ccttcactgc agcagcaaca actcgttttg gttcaggttg
    16741 ggcatggttg gttgtcaaca aagaagggaa acttgaagtg acttcaacag caaaccaaga
    16801 cacaccaatc tcagaaggta aaaaaccaat cttgggcttg gacgtttggg aacatgctta
    16861 ctacgtgaaa taccgcaacg tgcgtcctga ctacatcaaa gctttctttt cagtaatcaa
    16921 ctggaataaa gtagatgaat tgtacgcagc tgctaaataa tgatagttgg agggaagaat
    16981 tgttcttctc ttttttaggt tataagattc tggtctgaca aaatcgtcag acttttttca
    17041 tttttatgag aaacgtgcta actgctagaa attatggtag aataaagtat taagtaatcg
    17101 tggaaaaagg atatctatgc gaaaagaaat tgcacctgaa ttatacaatt ataacaagtt
    17161 tcctggtccg gagttccatt tacacgggga caaggtcgaa acggaaggga tagctttttc
    17221 cttggttgaa aatatcaagg atgcctttga tgtgacgact tttaatcagc gtttttcaga
    17281 agtcttaacc aagtttgatt atatcgtggg ggactggagc aacgaacagc ttcgcctacg
    17341 aggtttttac aaggatgacc gaacagaaga aaaacttgaa aaaatcagtc gtttacaaga
    17401 ctacctttta gagtattgta gttatggttg tgcctatttt gtcttagaaa atgaagcccc
    17461 taagcgagca tcatttgaca agaaaatgcg taagacggaa gaagaaacac cttctagaaa
    17521 aggaaagaaa ccgactcaaa ctaaacgaaa gtcgaatgca gataagaaaa atagacgtcg
    17581 tcagaaagac cagcattctc agaaagagga caagggacaa cgtcattttg tcattcgtca
    17641 gaagtgagta gagaataagg agaagaaatg aaaccctcaa ttcatagttt ggtacatcaa
    17701 accatgcagg aatgggtatt ggagcaggga gaaaagaaat tccgtgcaga tcaaatctgg
    17761 gaatggctct accgtaaacg tgtgcagtca tttgaagaaa tgaccaacct ttccaaggat
    17821 ttgattgcta agctcaatga ccagtttgtg gtcaatccct tgaaacaacg tattgtgcaa
    17881 gagtctgctg atggtacagt caaatatctc tttgaattgc ccgacggtat gttaattgag
    17941 actgtactca tgcgtcaaca ctatggttta tctgtctgtg tgaccactca ggtcggctgt
    18001 aatatcggtt gtaccttctg tgcctctggt ttgattaaga agcagcgtga cctcaataac
    18061 ggtgaaatcg tagcgcaaat catgctggtt cagaaatact ttgatgagcg tggtcaggat
    18121 gaacgcatca gccatatcgt tgtcatggga atcggtgagc cctttgataa ttacaacaat
    18181 gtcttgaatt tcgtttgtac tatcaatgat gataaaggaa tggctatcgg tgctcgtcac
    18241 atcacgattt caacctcagg tttggctcat aaaattcgtg actttgctga tgaaggggtt
    18301 caggtcaatc ttgccgtgtc tcttcacgca cccaacaatg aacttcgttc aagtatcatg
    18361 aaaattaacc gtgcctttcc gattgaaaaa ctctttgctg ctattgaata ctatattgag
    18421 acaacaaacc gtcgtgtaac ctttgaatat atcatgctta atgaagtcaa cgacggtgta
    18481 gaacaagcct tggaattggc tgaattgctc aagaacatca agaaattgtc ttatgtaaac
    18541 ttgattcctt ataacccagt tagtgagcat gaccaatata gccgtagtcc caaagagcgc
    18601 gtgttggctt tctatgatac gcttaagaaa aaaggggtca actgtgtggt tcgtcaagag
    18661 catggtacag atattgacgc agcttgtgga caattgcgct ctaacacaat gaaacgtgac
    18721 cgccagaagg cagtcgcagc ggtaaatcct taatgatgaa gaagacttat aatcatattt
    18781 tggtctgggg agtcattttc tatagcattt gcattgtctg tttttgcttt actcctcaag
    18841 aacaatctac cgtgggagtg ggaactccag gtattcagca tcttggacgc ctggtttttc
    18901 ttttgactcc tttcaattct ctctggaaac tgggcgaagt gagtgacatt ggacaattat
    18961 gttggatttt tttacaaaat atcctcaatg tcttcttgtt ttttcctctg attttccaac
    19021 tcctttatct atttccaaat ttgcggaaaa caaaaaaggt ccttcttttt agttttcttg
    19081 tgagtcttgg aatcgagtgt acgcaattaa tcttggactt tttctttgat ttcaatcgcg
    19141 tctttgagat tgatgatttg tggaccaaca ctttgggtgg ctatctggct tggctccttt
    19201 ataaacgatt acataaaaac aaggtaagga attaaaatga gtattttaga agttaaaaat
    19261 ctgagtcacg gttttggtga ccgtgcaatt tttgaagatg tgtccttccg tctcctcaag
    19321 ggagaacata tcggcctggt cggtgccaat ggtgaaggaa aatcaacctt tatgagtatc
    19381 gtgactggta aaatgctgcc agatgaagga aaggttgagt ggtccaaata tgtgacggct
    19441 ggttacttgg atcagcactc tgtccttgct gaaagacagt cggtgcgtga tgttctccgt
    19501 acggcttttg atgagctttt caaagctgaa gctcgtatca atgacctcta tatgaaaatg
    19561 gctgaagacg gcgcggatgt tgatgctctc atggaagaag taggagaact tcaagaccgt
    19621 ctggagagtc gtgatttcta taccttggat gctaagattg acgaagtagc gcgtgctctt
    19681 ggtgttatgg actttgggat ggatacggat gtaacttctt tgtcaggtgg gcaaagaacc
    19741 aaggtgcttt tggcaaaact tctccttgaa aagcctgata ttttgctgtt ggacgagccg
    19801 accaactact tggatgctga gcatattgat tggctcaagc gctatctcca aaactatgag
    19861 aatgcctttg ttcttatttc gcacgatatt ccattcctca atgacgttat taatattgtc
    19921 tatcatgtgg aaaatcaaca gctgacgcgt tactctggtg actactacca gttccaagaa
    19981 gtttatgcta tgaagaaatc tcagctagag gcagcctacg aacgccagca gaaagagatt
    20041 gcagacctca aggactttgt ggctcgtaat aaagcccgtg ttgcaactcg taatatggct
    20101 atgtctcgtc aaaagaaatt ggataagatg gatattatcg aactccaaag tgagaaacca
    20161 aaaccatcct ttgatttcaa accagctcgt acaccagggc gctttatctt ccaagccaag
    20221 aacttgcaaa ttggttacga ccgtcctctt actaagcctt taaatcttac cttcgaacgc
    20281 aatcaaaagg ttgcgattat tggtgctaat ggtattggaa aaacaactct cttgaagagt
    20341 ctcttaggca ttatctcgcc aatcgctggg gaagtggagc gtggagatta tttagaactt
    20401 ggttattttg agcaggaagt agaaggcggt aatcgccaaa ctcctcttga agctgtctgg
    20461 aatgcctttc ctgcccttaa tcaagcagaa gtccgtgcag cccttgcccg ttgtggtttg
    20521 acaaccaaac atattgaaag ccagattcaa gtattatcag ggggagagca agccaaggtt
    20581 cgtttctgtc tcttgatgaa tcgtgaaaac aacgttttag tgctggacga gccgaccaac
    20641 catttggatg tggatgcaaa ggatgagctc aaacgcgctc tcaaagaata caggggatct
    20701 atccttatgg tctgccacga gccagacttt tatgaaggtt ggatagacca aatatgggat
    20761 tttaataatt taacttaaga atgagagtaa aagaaataca gtaccgaatg tggatactgt
    20821 atttttttgg tttttaagat ttaaaatcgt agtctttcac cacttcgatg ctgtcgattg
    20881 tgatagcagt agttggcttg tctttttcat ctttttcggc tttagcaatc ttatccacaa
    20941 catccatacc gtcaatcact tgaccaaaga ctgggtgttt gccatctaga ctagggtttc
    21001 caccttcttt gtaggcttcg ataattttct gtggatactt gcttgtaggg agtttagaag
    21061 aggtatctgt agagttttgg ttgatgaaga actggctgcc attggtgttt ggttgaccag
    21121 tattagccat agcaagagca ccacggatgt tatacaaata aggagtaatc tcgttcttga
    21181 aaccagttcc tttgtcttta gtcttatcct tgtcatgcca tatggactga ccacctgtac
    21241 cgtccccttt tggatctcca gtttggacca taaagccatc gatgacacgg tggaaggtaa
    21301 taccgttata gtagccttct ttggcgtgag tgaggaaatt ttcaaccgct agaggagcga
    21361 gtttagggaa gagtttaatg cgaatatcac cttggcttgt gtggagaatc acttcggctt
    21421 catcttcagc aacttcctta gatagttgtg ggaaattggc gttttcgttt gttaaagcat
    21481 cgtttaactc cttggcagat tgggcagcta ctttggaact ttcttcagca gcaagactgg
    21541 aatcaacata atcatcacca cgcagactgc gttggacgct gctacaccca gctagggcta
    21601 cagtagacag taaaagaagg gttgctagtt ttttcattct gatcctctca aaaattcatt
    21661 tataccattg taccctaaaa ggaagtggat ttcaaatatt agtagtttac agaactggct
    21721 tagataatag ttgggatttc atcatcatct tgaaaatctt caacttcttc aacttcttcc
    21781 ccagtaaatg gtttctgaaa agaacttagt ataaaacggg caattggttc aacaattagg
    21841 aaatttagag gaagagctgc aataaagttt acgaaccagg cgcttagata ggtattgggt
    21901 gtgatagcaa tgccattgta aaaaagtcca tagaaggaca tgaaagtgac cagctaattc
    21961 ttcttctgaa aaatgctcat gaagggcttg atccaggtcg caagatttca ttttagaaag
    22021 tccagtaact cccttcttct tcaggatatt ctttttcatg gtattattta gatggtcaag
    22081 tgagtcaaaa gaagtttcga caagagcata ccctttttct accagagttt ttagatgttt
    22141 aggggcatca ataccataag tgtactcaaa gtattttgga aaccagatct taagaaagct
    22201 cgtaaagcta gccagttctc taaacgctaa gaactagcta caacacagca tttacaacac
    22261 ttcatggttc acaccatggg gtgtttttta atgattttaa gcaaaattca cacttaattg
    22321 aaagttattt aaattagatg aaaatttatt ttttgaaaaa gtgggaaaac attgattcta
    22381 agcgaatttt gaatcatatt cgaatgggag tttttaaaat catgtttcag tggtaaaagt
    22441 accaaactgg attctccata gtaaaatgat atctcctgct agtgaatcat ctgctaataa
    22501 gtccatattt cgcttgggac ttagaagcca agtatccaac tctcgttcag gcgatatgaa
    22561 gggtttgact tggtgttctt tataaaattt ttctaaaata gtattcacgg atagcatctt
    22621 tcaaacattt atttcctatt ctaacaaatt tctaaatgct ttaagaaatt tatagtctgt
    22681 caagtttttt tcttgacacc tgccagaaat ctgctataat agaacatgtg ctaaatagct
    22741 cagctatttc accgaaataa aaaattaaag aaatgagact ttaaaaatgg cagttaaaat
    22801 ccgtttgact cgtatgggtt ctaagaaaaa acctttctac cgtatcaacg tagcagattc
    22861 acgttcacca cgtgacggac gtttcatcga aacagttgga acttacaacc cacttgttgc
    22921 tgaaaaccaa gtaactttga aagaagaccg cgttcttgca tggttggcta atggagctca
    22981 accttcagac acagtacgta acatcctttc aaaagaaggc gtattgaaaa aattccacga
    23041 ttctaaattc tcaaaataag tttaaagtag gttgacagat ggatacgatt gaaaatctca
    23101 ttattgcgat tgtgaaaccc ttaatttcac aaccagatgc cttaactatc aagattgagg
    23161 atacaccaga atttttggaa tatcatttga atcttgatca aagcgatgtg ggtcgtgtaa
    23221 tcggtcgtaa gggtcgcact atttctgcga taagaacgat tgtctactct gtcccaactg
    23281 aatacaaaaa agtaagaatc gttattgacg aaaaataaga agggcgggac ggatgtctcg
    23341 cttttttgtg tggaatagaa gatatagtaa aatgaaataa taacaggaca aatcgatcag
    23401 gacagtcaaa tcgatttcta acaatgtttt agaagtaaag gtgtactatt ctagtttcaa
    23461 tatactataa aagattgaac gtttaggcaa ttccaagact acttaatcga acattaacag
    23521 cagtctcgga ctgatgaagg tctttttatg aagttagtgg aggaagtcgg agaagtagcc
    23581 gaggttttga ataggcgctc tggtcgaaaa gaagggatag gattcgaacg aggaacttgc
    23641 cagagaactg gctgatatca tttactacac cgtcgcaatc gtagctatta atcatattga
    23701 ccttaccaag actgtctttg agaaagacaa aaccgcagcc gttaattacc aacataaaca
    23761 taatttggaa ggattattga agggaaagta gagatattgt ccccttcctc caacttgaga
    23821 aaatccttgg aacgtgataa aataaaggat aaggattttt aataattcat tatatagaat
    23881 cagtggattt ctttatgaag aggtttgaag tatctacaga aattggtagc ctctctgtta
    23941 cttatcaaaa gcaaaagaaa gtgctagttt gtctaaacgg agcaggtttg ctaccaagtt
    24001 atgaaaattt ttcacttata cttgaaaaac ctcctcctac aattggttat ttgacaattg
    24061 attttccgaa cacaggtagg agtccgattc atgaccaagc tggaaaaaat ctagataatc
    24121 ttgcagatgc ggtttatgaa gtacttgaag aattaggaat ttctgaatat atactttgtg
    24181 cacatagttg gagtggaatt ttagcttgca aattactcga gaaaccaatt aagcgtcaga
    24241 ctttagtagc aattgaaccg acaactaaaa aagtcatgtt tgctgatttt tcagaaaatc
    24301 cttatccaga aatggaagag cagatgaggc tgattgacga gtgtggtcct gaactttatt
    24361 ttaagaactt aactcaagca acatttagtc ctgaaacgaa taaaaaaatc tgggaattaa
    24421 tgcaagaaaa aggcttagag ttggaaaatc aagatccaga atttcagata tctggagaga
    24481 ttactgagga agattttgag gatgtatcta tagaagctca tattcctgta tttgtttttt
    24541 gtcagcctta tagagaaaaa gagtacagag aatcagaata ttggacttcc aatactaaac
    24601 tcattttagg agggaatcac cattatttac aatggtcaga atcggaaaaa attgcggcta
    24661 ttattcgaga attgttagaa taagatggaa aaaaggagat tacaggagac aagatgaact
    24721 actttaatgt tgggaaaatc gttaatacgc agggattaca gggtgagatg cgagtcttgt
    24781 ctgtgacgga ttttgcagaa gaacggttta aaaaaggagc tgagctggct ttgtttgatg
    24841 aaaaagatca gtttgtccaa acagtgacca tcgctagcca ccgtaaacag aagaactttg
    24901 acattattaa attcaaagat atgtaccata tcaatactat cgaaaagtac aagggataca
    24961 gtctcaaggt cgctgaggaa gatttgaatg acctagacga tggtgaattt tactatcacg
    25021 agattatcgg tttggaagtc tatgagggtg atagcttggt tggaaccatc aaggaaatcc
    25081 tgcaaccagg tgctaatgat gtctgggtgg tcaaacgaaa aggcaaacgt gatttgcttt
    25141 taccttatat cccaccagtg gttctcaatg ttgatattcc aaataaacgg gtcgatgtgg
    25201 aaatcttaga agggttagac gatgaagatt gatattttaa ccctctttcc agagatgttt
    25261 tctccactgg agcactcaat cgttggaaag gctcgagaaa aagggctctt ggatatccag
    25321 tatcataatt ttcgagaaaa tgctgaaaag gcccgtcatg tagatgatga gccctacgga
    25381 ggcggtcagg gcatgttgct cagagtacaa cctattttcg attcctttga tgctattgaa
    25441 aagaaaaatc cgcgcgttat tctcctcgat cctgctggaa agcagtttga tcaggcttat
    25501 gctgaagatt tggctcaaga ggaagagcta atctttatct gtgggcacta tgagggttat
    25561 gatgagcgca ttaagacctt ggtaacagat gagatttccc taggcgacta tgtcctcact
    25621 ggtggagaat tggcagctat gaccatgatt gatgctacag ttcgcctgat tccagaagtg
    25681 attggcaagg agtctagcca ccaagatgat agtttttctt caggtctttt agaatatcct
    25741 cagtacacac gtccttatga ttatcgaggc atggtcgtgc cagatgtatt gatgagtggc
    25801 caccatgaaa agattcgtca gtggcgattg tacgagagtt taaagaaaac ctacgagcgc
    25861 agaccggatt tacttgaaca ttatcaactg acagtagaag aagaaaaaat gctggcagaa
    25921 atcaaagaaa acaaagaata aaggagaaac ctatgcaagt aatcaaacgt aatggcgaaa
    25981 ttgctgaatt taatccagat aagatttacc aagccatctt gaaggcagcc caaactgttt
    26041 atgttttgac agatgatttg cgtcaaaatc ttgctcaagt cactaagaag gtagttttgg
    26101 atttacaaga agccaaggtg gaacgtgcga ctatcagtat gattcaatct atggttgaac
    26161 atcgtttatt gggcgcaggt tacattacca ttgcagaaca ctacatttcc tatcgtttac
    26221 aacgtgactt ggaaagaagt ggttatggag atcatatcgc agttcattta cattttgaac
    26281 aaattcgcta agaaaaaaga gtgggatgaa gcaactacat ctcactcttt cttaaatcta
    26341 tttttttggg ctgtttggac agttgagggg acaaatcgca ggcgttgaat atcgcttata
    26401 cggataatcc ggctcacatt tttggaaaaa tttttcacga taatttgctg gccttgctga
    26461 tcatatttga tgatgtcacc tgtaaagctt gtctcagata agataaggtg aacagcggtt
    26521 tgtttctgga tagcctcttc aatagtggct gtaagggagt tggtttcagt ctggtcaggt
    26581 tggtcatatc catttaaaaa atcatgtatt ttatttagaa cttgctggaa tttatgtctc
    26641 atattggcct cccttctttt atatcaatat tatataaaat tttcctaaaa tctacaagat
    26701 tttacgaata aactaatgaa actaaaaaag gagaagaaaa tggcagaatt tacatttgaa
    26761 atcgaagagc acttgttgac tctttctgaa aacgaaaaag gttggaccaa ggaaattaac
    26821 cgtgtgagct ttaatggtgc ccctgcaaag tttgatattc gtgcttggag tccagaccat
    26881 actaaaatgg gcaaagggat tactctctca aatgaagaat ttcaaacgat ggtggatgcc
    26941 tttaaaggca actaatactc ttcgaaaatc tcttcaaacc gcgtcagctt tgccttgccg
    27001 tatgtatggt tactgacttc gtcagtttca tccacaacct caaaacaatg ttttgagctg
    27061 acttcgtcag tttcatccac aacctcaaaa caatgttttg agctgacttc gtcagtttca
    27121 tccacaacct caaaacagtg ttttgagcag cctgcggcta gcttcctagt ttgctctttg
    27181 attttcattg agtataagtt ttcaaaataa aagaaaagga tattgagtca tgataactcg
    27241 gtatcctttt ttagttagta aagtaagcct gatttttaag gcgttgaagt aggggacggc
    27301 taataaaact aatagccaga agtttgccaa ggtctggaat gataaaggga agaaccccca
    27361 caacaagagc tttttcaaat gccattccag ctaggaaatg caagctgaga atcccgccga
    27421 caaagacaag ggcatcaccc aagaggtttg caagaaaaat cttaacaaca ccactcttgc
    27481 tgttggttag agaggaagta agtccagagt aaacgagata aaaccaaaga tagcctgcag
    27541 tagggccaac taaagcctga aaaccagctc cacctcctgc aaagacagga agaccgatag
    27601 cacctagaag aagatagagt ccagcagaaa gtacagcctc tctcggtcta aagacagtag
    27661 caatcaagcc gattgcaaag ttttgcagag tgaagggaac aggtccaatt ggaagactga
    27721 tttgtgccaa agcagcaatg agagcagccc caatagcagg gatagcataa acgtgagctt
    27781 ttttcaaaat agttaacctc ttttctaatg tatagtaact attatactca tataggagtc
    27841 gatgtcaacc attttttaaa aacaaggtaa caaaaactgt aacagccgat tttcgtgact
    27901 agtcaagttg gataattttt ttgttgattc gaaaatcatt aaaaaagaag cagacatatt
    27961 tatatcagct tcttttgttt cgattaacgc atggttacaa attcttcaga tgcagttggg
    28021 tgaattgcca cagttgcatc aaagtcagcc ttggttgctc ccattttgat agcaacggca
    28081 aatccctgaa tcatttcatc aacgccgtag ccaattccat gaagtccgac aactttttct
    28141 tctgaaccag ctgttatgag tttgaaacgg gattcttgac ggttgcgagt gcaagcagag
    28201 tacatagatg caaagcttga tttataaacc ttgatttggt cttgaccgta ttctttaata
    28261 gcttgctctt ctgtcaaacc aacagttccg atagcagggt gtgaaaagac aacagttgga
    28321 atagttgagt aatccatttt tgcagtagtt tttccgttaa agagacgttc agatagggta
    28381 cgtccggcct tgattgcaac tggagtcagt tctttctcgc ccgttacatc acctagagca
    28441 tagagtccct caacaacagt attttggtat tcatccactt ggataaagcc acgttcgttc
    28501 agagtcactc cagctttttc aagttgcaag cccttaacgt ttggacggcg gcctgtagcc
    28561 cagataactt ggctagctgt gtgactagta ccatcttcga aatgaatggt aatgccgtca
    28621 gtagtttttt ctaacttgac agggactttg tgagtgtgaa gtggtaagtt tgttctttcc
    28681 atttccttga ccaaaccttc aacgatgtag gaatcaaaac cacgtaaagg acgatcgcgg
    28741 cgaacaaaga gatctgtctt gacaccaaaa gtgtggagta cgccagctaa ttcaacggcg
    28801 atataaccag cgcctagaat ggcaactgac tctggaagtt cttcccaggc aaatacatca
    28861 tcagaagagc cacctagctc agcaccagga atattaggaa tacttggatg ggcacctgta
    28921 gcaatcacga tatgtttagc acgaatcagt tcaccattta cgcttacagt atgagaatct
    28981 acaaattcag catgaccttc aatcaagtct acaccgttgc gtttaaaact accatcataa
    29041 gaagaacgag cgcgatcaat gtaggcttca cgattgcgac gtagggttgc aaagtcaaag
    29101 ttaagatcag tagtcttaaa gccgtagtct tctccaaatt gatggaaagt ctcagcgatt
    29161 tgcgccccgt accacatgat ttttttagga acacaaccga cgttgacaca ggttccacct
    29221 aatttctttt cctcaataac ggctgctttg gctccatgtt caccagcacg gttcatggta
    29281 gcgattcctc cgctacctcc accgatagca atgatatcat attctctcat tgaaaactcc
    29341 tttgtaatct tttaaatagt agagcgtctt ttttgatagt tatattttat tctttttttg
    29401 atttgattgc aaaaatctgc tacgcacaaa aaattgcaaa aaagcttgcc aaataagtca
    29461 agatagtgta ttatatatct agtacaatag aaaagcaaaa ttccgaacga ttgtttaatc
    29521 ctgaactgcc attatttcca tctgaactgc attgtttgct ggagggaaat ttggtataat
    29581 agcaaagtat tgtaaaaaag aaaaggagtt tcattatgaa gaaaaagaat ggtaaagcta
    29641 aaaagtggca actgtatgca gcaatcggtg ctgcgagtgt agttgtattg ggtgccgggg
    29701 ggattttact ttttagacaa ccttctcaga ctgctctaaa agatgagcct actcatcttg
    29761 ttgttgccaa ggaaggaagc gtggcatcct ctgttttatt gtcagggaca gtaacagcaa
    29821 aaaatgaaca atatgtttat tttgatgcta gtaagggtga tttagatgaa atccttgttt
    29881 ctgtgggcga taaggtcagc gaagggcagg ctttagtcaa gtacagtagt tcagaagcgc
    29941 aggcggccta tgattcagct agtcgagcag tagctagggc agatcgtcat atcaatgaac
    30001 tcaatcaagc acgaaatgaa gccgcttcag ctccggctcc acagttacca gcgccagtag
    30061 gaggagaaga tgcaacggtg caaagcccaa ctccagtggc tggaaattct gttgcttcta
    30121 ttgatgctca attgggtgat gcccgtgatg cgcgtgcaga tgctgcggcg caattaagca
    30181 aggctcaaag tcaattggat gcaacaactg ttctcagtac cctagaggga actgtagtcg
    30241 aagtcaatag caatgtttct aaatctccaa caggggcgag ccaagttatg gttcatattg
    30301 tcagcaatga aaatttacaa gtcaagggag aattgtctga gtacaatcta gccaaccttt
    30361 ctgtaggtca agaagtaagc tttacttcta aagtgtatcc tgataaaaaa tggactggga
    30421 aattaagcta tatttctgac tatcctaaaa acaatggtga agcagctagt ccagcagccg
    30481 ggaataatac aggttctaaa tacccttata ctattgatgt gacaggcgag gttggtgatt
    30541 tgaaacaagg tttttctgtc aacattgagg ttaaaagcaa aactaaggct attcttgttc
    30601 ctgttagcag tctagtaatg gatgatagta aaaattatgt ctggattgtg gatgaacaac
    30661 aaaaggctaa aaaagttgag gtttcattgg gaaatgctga cgcagaaaat caagaaatca
    30721 cttctggttt aacgaacggt gctaaggtca tcagtaatcc aacatcttcc ttggaagaag
    30781 gaaaagaggt gaaggctgat gaagcaacta attagtctaa aaaatatctt cagaagttac
    30841 cgtaatggtg accaagaact gcaggttctc aaaaatatca atctagaagt gaatgagggt
    30901 gaatttgtag ccatcatggg accatctggg tctggtaagt ccactctgat gaatacgatt
    30961 ggcatgttgg atacaccaac cagtggagaa tattatcttg aaggtcaaga agtggctggg
    31021 ctgggtgaaa aacaactagc taaggtccgt aaccaacaaa tcggttttgt ctttcagcag
    31081 ttctttcttc tatcgaagct caatgctctg caaaatgtag aattgccctt gatttacgca
    31141 ggagtttcgt cttcaaaacg tcgcaagttg gctgaggaat atttagacaa ggttgaattg
    31201 acagaacgta gtcaccattt accttcagaa ttatctggtg gtcaaaagca acgtgtagcc
    31261 attgcgcgtg ccttggtaaa caatccttct attatcctag cggatgaacc gacaggagcc
    31321 ttggatacca aaacaggtaa ccaaattatg caattattgg ttgatttgaa taaagaagga
    31381 aaaaccatta tcatggtaac gcatgagcct gagattgctg cctatgccaa acgtcagatt
    31441 gtcattcggg atggggtcat ttcgtctgac agtgctcagt taggaaagga ggaaaactaa
    31501 gatgcagaat ctgaaatttg ccttttcatc tatcatggct cacaagatgc gttctttgct
    31561 tactatgatt gggattatta tcggtgtttc atcagttgtt gtgattatgg ctttgggtga
    31621 ttccctatct cgtcaagtca ataaagatat gactaaatct cagaaaaata ttagcgtctt
    31681 tttttctcct aaaaaaagta aagacgggtc ttttactcag aaacaatcag cttttacggt
    31741 ttctggaaag gaagaggaag ttcctgttga accgccaaaa ccgcaagaat cctgggtcca
    31801 agaggcagct aaactgaagg gagtggatag ttactatgta accaattcaa cgaatgccat
    31861 cttgacctat caagataaaa aggttgagaa tgctaatttg acaggtggaa acagaactta
    31921 catggacgct gttaagaatg aaattattgc aggtcgtagt ctgagagagc aagatttcaa
    31981 agagtttgca agtgtcattt tgctagatga ggaattgtcc attagtttat ttgaatctcc
    32041 tcaagaggct attaacaagg ttgtagaagt caatggattt agttaccggg tcattggggt
    32101 ttatactagt ccggaggcta aaagatcaaa aatatatggg tttggtggct tgcctattac
    32161 taccaatatc tcccttgctg cgaattttaa tgtagatgaa atagctaata ttgtctttcg
    32221 agtgaatgat accagtttaa ccccaactct gggtccagaa ctggcacgaa aaatgacaga
    32281 gcttgcaggc ttacaacagg gagaatacca ggtggcagat gagtccgttg tatttgcaga
    32341 aattcaacaa tcgtttagtt ttatgacgac gattattagt tccatcgcag ggatttctct
    32401 ctttgttgga ggaactggtg tcatgaacat catgctggtt tcggtgacag agcgcactcg
    32461 tgagattggt cttcgtaagg ctttgggcgc aacacgtgcc aatattttaa ttcagttttt
    32521 gattgaatcc atgattttga ccttgttagg tggcttaatt ggcttgacaa ttgcaagtgg
    32581 tttaactgcc ttagcaggtt tgttactgca aggtttaata gaaggtatag aagttggagt
    32641 atcaatccca gttgccctat ttagtcttgc agtttcggct agtgttggta tgatttttgg
    32701 agtcttgcca gccaacaagg catcgaaact tgatccaatt gaagcccttc gttatgaatg
    32761 agatcaacaa gatggacact cgtctatctt gtttttgtat ggatttccct atcgaaattc
    32821 attaaaaatg tgatataatg aagtgttaga aaaacaggtt tcatttgcct ggaaaggaaa
    32881 aattatgtct gaaaaaaatt tttatattac aacgccgatt tactatccat ctgggaaact
    32941 tcatatcggt tctgcctaca caactatcgc atgtgatgtc ctagcacgtt acaaacgcct
    33001 gatgggctac gatgtatttt atctgacagg tcttgatgaa catggtcaga aaatccagca
    33061 gaaagcggaa gaagctggta ttacacctca agcctatgtt gatggaatgg cggttggagt
    33121 taaagaactc tggcaattac tagatatctc atacgataaa tttatccgta caactgatga
    33181 ctaccatgaa aaagttgttg cacaggtctt tgaacgctta cttgctcaag atgatatcta
    33241 cttgggtgaa tactctggtt ggtattcagt atcagacgaa gaattcttta cagaaagcca
    33301 gctggcagaa gttttccgtg atgaagctgg aaatgtgact ggtggtattg ctccatcagg
    33361 tcatgaggtt gaatgggttt ctgaagaatc atacttcctt cgccttagca aataccaaga
    33421 ccgtttggtc gaatttttca aagctcatcc tgaatttatc acgccagatg gtcgccttaa
    33481 tgaaatgcta cgcaacttca tcgagccagg tttggaagat ttggcggtat ctcgtacaac
    33541 ctttacatgg ggagtgcctg tcccatcaaa tccaaaacac gttgtctacg tttggattga
    33601 tgcccttctt aactatgcga cagctcttgg ctacgctcaa gacgaacatg gtaactttga
    33661 caagttctgg aatggaacag tcttccatat ggtaggaaaa gatatccttc gcttccactc
    33721 tatctactgg ccaatccttc ttatgatgtt ggatgttaaa ttacctgatc gtttgattgc
    33781 ccatggttgg tttgtcatga aagacggaaa aatgtctaag tcaaaaggga atgtcgttta
    33841 ccctgaaatg ttggtagagc gttatggact agatccactt cgttactacc tcatgcgtaa
    33901 ccttccagtt ggttcagacg gaacctttac tcctgaagac tatgtcggcc gtatcaacta
    33961 tgaattggct aatgaccttg ggaacctcct taaccgtacg gtttccatga ttaataagta
    34021 ctttgatgga caaatccctg cctatgtaga aggtgtgact gaatttgatc atgttcttgc
    34081 tgaggttgca gaacaatcaa tcgcagactt ccatacacac atggaagcag ttgactatcc
    34141 acgtgcgctt gaagcagtct ggactctgat ctctcgtacc aataaataca tcgatgagac
    34201 tgcaccatgg gtcttggaca aggatgaagc tcttcgtgac caattggcaa gtgtcatgag
    34261 ccacttggca gccagcattc gtgtagttgc tcacttgatt gaaccattta tgatggaaac
    34321 tagtcgtgca gttttgactc aacttggttt ggaagaagtt tctagtcttg aaaacttgag
    34381 tttggctgac ttcccagcag atgtgactgt agttgccaaa ggaacaccta tctttccacg
    34441 tctaaatatg gaagaagaaa tcgcctatat caaggaacaa atggaaggca ataaaccagc
    34501 agtcgaaaaa gaatggaatc cggacgaagt tgagctcaaa ctaaacaagg atgaaatcaa
    34561 gtttgaagac tttgacaagg ttgaaatccg tgtcgcagaa gtcaaagaag tgtctaaagt
    34621 agaaggttca gataagttgc ttcaattccg cttggatgct ggtgatggag aagatcgtca
    34681 gattctttca ggaattgcaa aatactatcc aaatgaacaa gaattggtcg gcaagaaagt
    34741 tcaaatcgtt gctaacctca aaccacgtaa aatgatgaaa aaatatgtca gccagggtat
    34801 gattctctca gctgaacatg atggcaaatt aacccttctc acagttgatc cagctgtacc
    34861 aaatggaagt gtgattgggt aaaagtagac aggactagtt caggctagtt ctgttttttt
    34921 atttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcgggt tgatcaaagc
    34981 actgctttga ggttgtagat gaaactgacg aagtcagctc aaagcactgc tttgaggttg
    35041 tagatgaaac tga
//
LOCUS       DAYYYC010000020        34880 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.020, whole genome shotgun sequence.
ACCESSION   DAYYYC010000020 DAYYYC010000000
VERSION     DAYYYC010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34880
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.020"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(1..2106)
                     /locus_tag="ACHBV5_001000"
     CDS             complement(1..2106)
                     /locus_tag="ACHBV5_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFM9966818.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSQLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     TKHLEADMEDGVLVIREKA"
     gene            complement(2715..3695)
                     /gene="mraY"
                     /locus_tag="ACHBV5_001001"
     CDS             complement(2715..3695)
                     /gene="mraY"
                     /locus_tag="ACHBV5_001001"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFM9966819.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(3697..5949)
                     /gene="pbp2X"
                     /locus_tag="ACHBV5_001002"
                     /gene_synonym="pbpX"
     CDS             complement(3697..5949)
                     /gene="pbp2X"
                     /locus_tag="ACHBV5_001002"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HFM9966820.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(5953..6270)
                     /gene="ftsL"
                     /locus_tag="ACHBV5_001003"
     CDS             complement(5953..6270)
                     /gene="ftsL"
                     /locus_tag="ACHBV5_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFM9966821.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(6282..7232)
                     /gene="rsmH"
                     /locus_tag="ACHBV5_001004"
     CDS             complement(6282..7232)
                     /gene="rsmH"
                     /locus_tag="ACHBV5_001004"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFM9966822.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            7398..7592
                     /locus_tag="ACHBV5_001005"
     CDS             7398..7592
                     /locus_tag="ACHBV5_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM9966823.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            7608..8150
                     /locus_tag="ACHBV5_001006"
     CDS             7608..8150
                     /locus_tag="ACHBV5_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HFM9966824.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNIIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            8161..8403
                     /locus_tag="ACHBV5_001007"
     CDS             8161..8403
                     /locus_tag="ACHBV5_001007"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966825.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            8414..8749
                     /locus_tag="ACHBV5_001008"
     CDS             8414..8749
                     /locus_tag="ACHBV5_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966826.1"
                     /translation="MKSLARLLIIHVFISIFLFFALTSGAISHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(8859..9860)
                     /locus_tag="ACHBV5_001009"
     CDS             complement(8859..9860)
                     /locus_tag="ACHBV5_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM9966827.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(9920..11821)
                     /locus_tag="ACHBV5_001010"
     CDS             complement(9920..11821)
                     /locus_tag="ACHBV5_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HFM9966828.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHYSKDYEKVKRSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKSYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIRVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(11843..12136)
                     /gene="yajC"
                     /locus_tag="ACHBV5_001011"
     CDS             complement(11843..12136)
                     /gene="yajC"
                     /locus_tag="ACHBV5_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFM9966829.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(12136..12954)
                     /locus_tag="ACHBV5_001012"
     CDS             complement(12136..12954)
                     /locus_tag="ACHBV5_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFM9966830.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(12941..13720)
                     /locus_tag="ACHBV5_001013"
     CDS             complement(12941..13720)
                     /locus_tag="ACHBV5_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFM9966831.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(13735..14226)
                     /locus_tag="ACHBV5_001014"
     CDS             complement(13735..14226)
                     /locus_tag="ACHBV5_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM9966832.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(14237..15427)
                     /locus_tag="ACHBV5_001015"
     CDS             complement(14237..15427)
                     /locus_tag="ACHBV5_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFM9966833.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(15439..15873)
                     /locus_tag="ACHBV5_001016"
     CDS             complement(15439..15873)
                     /locus_tag="ACHBV5_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFM9966834.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            16145..16960
                     /locus_tag="ACHBV5_001017"
     CDS             16145..16960
                     /locus_tag="ACHBV5_001017"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFM9966835.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            16979..17620
                     /locus_tag="ACHBV5_001018"
     CDS             16979..17620
                     /locus_tag="ACHBV5_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HFM9966836.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            17651..18652
                     /locus_tag="ACHBV5_001019"
     CDS             17651..18652
                     /locus_tag="ACHBV5_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HFM9966837.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            18662..19291
                     /locus_tag="ACHBV5_001020"
     CDS             18662..19291
                     /locus_tag="ACHBV5_001020"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HFM9966838.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(19435..19497)
                     /locus_tag="ACHBV5_001021"
                     /pseudo
     CDS             complement(19435..19497)
                     /locus_tag="ACHBV5_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596946.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(19679..20055)
                     /gene="tnpA"
                     /locus_tag="ACHBV5_001022"
                     /pseudo
     CDS             complement(19679..20055)
                     /gene="tnpA"
                     /locus_tag="ACHBV5_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(20408..20473)
                     /locus_tag="ACHBV5_001023"
     CDS             complement(20408..20473)
                     /locus_tag="ACHBV5_001023"
                     /inference="COORDINATES: protein motif:HMM:TIGR01167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966839.1"
                     /translation="MASLGFLLLGAFYLFRRGKNN"
     gene            complement(20590..23487)
                     /locus_tag="ACHBV5_001024"
                     /pseudo
     CDS             complement(20590..23487)
                     /locus_tag="ACHBV5_001024"
                     /inference="COORDINATES: protein motif:HMM:NF014883.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="polysaccharide lyase beta-sandwich
                     domain-containing protein"
     gene            23710..24186
                     /locus_tag="ACHBV5_001025"
     CDS             23710..24186
                     /locus_tag="ACHBV5_001025"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFM9966840.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            complement(24408..26621)
                     /locus_tag="ACHBV5_001026"
     CDS             complement(24408..26621)
                     /locus_tag="ACHBV5_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HFM9966841.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSKTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAIPLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNKNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQVAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GILDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPMYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLAFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTI
                     PVFAKSGAIIPLVGSEIDMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELTLQGDSSIVPSNRRHRIHFKGTNVSIIELPNKNDTARFECKDNKTISLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(27022..27198)
                     /locus_tag="ACHBV5_001027"
     CDS             complement(27022..27198)
                     /locus_tag="ACHBV5_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966842.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            complement(27578..28924)
                     /gene="celB"
                     /locus_tag="ACHBV5_001028"
     CDS             complement(27578..28924)
                     /gene="celB"
                     /locus_tag="ACHBV5_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFM9966843.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVIIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDVFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            complement(29004..29510)
                     /locus_tag="ACHBV5_001029"
     CDS             complement(29004..29510)
                     /locus_tag="ACHBV5_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966844.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            complement(29541..29855)
                     /locus_tag="ACHBV5_001030"
     CDS             complement(29541..29855)
                     /locus_tag="ACHBV5_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HFM9966845.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            complement(29865..31844)
                     /locus_tag="ACHBV5_001031"
     CDS             complement(29865..31844)
                     /locus_tag="ACHBV5_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFM9966846.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            complement(31962..32276)
                     /locus_tag="ACHBV5_001032"
     CDS             complement(31962..32276)
                     /locus_tag="ACHBV5_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HFM9966847.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            complement(32406..32644)
                     /locus_tag="ACHBV5_001033"
                     /pseudo
     CDS             complement(32406..32644)
                     /locus_tag="ACHBV5_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET transporter"
     gene            complement(32696..34132)
                     /locus_tag="ACHBV5_001034"
     CDS             complement(32696..34132)
                     /locus_tag="ACHBV5_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFM9966848.1"
                     /translation="MTTFKDRFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITSGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            complement(34322..34660)
                     /locus_tag="ACHBV5_001035"
     CDS             complement(34322..34660)
                     /locus_tag="ACHBV5_001035"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HFM9966849.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            complement(34812..34880)
                     /locus_tag="ACHBV5_001036"
                     /pseudo
     CDS             complement(34812..34880)
                     /locus_tag="ACHBV5_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931945.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
BASE COUNT        10573 a         7531 c         5776 g        11000 t
ORIGIN      
        1 ttaggctttc tcacgaataa ccaaaacgcc atcttccata tctgcttcca gatgtttagt
       61 atctaaatga tccaagtgga agtctgtcac cttatcacga atttcttgtt caaccacgcg
      121 acggagagga cgaaccccca tgacttcgtc gtaaccttct tctgtgatat aatctttagc
      181 cgcttgactg actaccaagt caatgtcttt cttagccaag gtttggttaa cttcagccaa
      241 catcaaatct acaatcttag aaaggtcttc cttagtcaat tgtgagaact cgatgactgc
      301 attaaagcgg ttgaggaatt ctggacggaa gaagggtttc aaacggtcca tcaattctgg
      361 tttatccgca tcttctgtca agttggcttc atagccaaat ccagcatttg aggtcgcaat
      421 aatgacagtg ttcttgaagt ttactgtatt tccttgacca tctgtcaaac gaccatcatc
      481 tagaacttgg aggagaaggg taataacttg aggatcagcc ttttcaattt catccaagag
      541 aatgatagag tatggattgc gacgaacacg ttctgttaag gtattgctat tgtcatcata
      601 acccacatag cctgctgttg taccaattag cttagaaaca gctgtgcggt cactgtattc
      661 agacatatcc aaacggataa tcgcatcctg ggttccaaac atatcgagtg ccaattgctt
      721 agcaagctcc gtcttaccaa ccccagtaga ccctacaaag aggaagctgc cgattgggcg
      781 atttccttca tcaaaaccag cacggttacg acggatagcg cgagctacag cttctacggc
      841 cttatcttga ccaatcacct tgtcttgcaa gcgatgagcc atatctttca aacgttcgat
      901 atctgaagct cccatttgcg atactgggat acctgtcatt cgttccacag attcagccac
      961 atcgttgaca cttgcagtca ctttcatatc ttctgtgtgg ttttcgattt tcttttccaa
     1021 ttctgcaatg cgtgttttat agtttagagc tgcttcaaaa tcttctgctt caactgcttt
     1081 ttcttgcttg tctttttccg tttcgatttc tcgttcaaca gcatgcacat ctgttactgg
     1141 atgttgagcc gccaagtgag cagccgttac atcgacaagg tcaatagcct tatctggcaa
     1201 gctacgttga ggaatgtatt gaacagaata atccaccgct gctttcaaga cttcgtctgg
     1261 caagatgaca ttgtggtgtt gttgatagag gtcacgaatt ccttgaagaa ttttaaaagt
     1321 attctctgcc gaaggagcat tgaccttcac ttcgttgaaa cgacgagcaa gagcagcatt
     1381 cttcaagatg gtgttacggt attcgtcttg agttgttgcc ccaatcactg tcaattctcc
     1441 acgagagaga gctggcttga gaatatccgc aagtccttta gaaccactgt ctccaccagt
     1501 gctaccagca ccaagaattt ggtgaatttc atcaaagaag aggataatat tccctgcttc
     1561 tttcacttca ttgactaagt tttggacatt ttcttcaaag ctaccacggt attgagtacc
     1621 agcctcaaga cctgagatat caatagaaat aatttccttg ttcttgatag cagcaggaac
     1681 atctccgttc acaatggctt gcgctagacc ttcgacaact gctgtcttac caacacctgc
     1741 atctccgacc aaaacaggat tgttcttggt gcggcgtgag aggatttcag atgtttcttg
     1801 aatttccttg tttcgtccga taacaggatc caacttgccc tcacgcgctt ctgctgttaa
     1861 gtttcgacct agttttgcaa ggacaccgtc ttgtttcata cctgatgcct gttgtggcat
     1921 ttgcacatca gtttctgcat ttcctggtaa ttgaccagtc gcacgatagt gagcaaattc
     1981 ctcaggtgtg acttcgcgtc cattaattaa gtaacggcga ttttcagaac tgtatcctcg
     2041 cataccaccc atcaattggt taaataaatc atccatgtta ttaaaattat taaagttgtt
     2101 attcatattc tttacctctt tttgtttact tagttatgat tactgatatt gactatcttt
     2161 gaccattgtt ttaaaaaatt tagactagct agatcgctac cctacgtact atttctggtt
     2221 tttctttttc aagcaggagt agactatctt tacttctgaa gatttctaga tgaaacatag
     2281 acccacctct ttctatttta ctttaaataa gtgttctagt aaggctttca tttaccttac
     2341 gttcataata tactacattg gtcagaaaag gtcaagagtt ttgactttaa ctgaccaata
     2401 tttttttaca ctcttcgaaa acctcttcaa accacatcag cttctcctta tctacaacct
     2461 caaaaccgtg ttttgagctg acttcgtcag ttctatcaac catctcaaaa ctgtatatta
     2521 aaacgaaata agaacaggac aaatcaatca ggacagtcaa atcgatttct aacaatattt
     2581 tagaagtaga tgtgtactat tctagtttca atctactata ttttgagcag cctaaagtta
     2641 gctttctagt ttgttctttg attttcattg tgtatttaaa cacaaaaaca ccctgaaaca
     2701 tcagggtgcc attcttacat caaatataaa attgctaggg tcaggagact tgctagaagt
     2761 cccactcccc aaaagaagaa gtcaaccttc cactcgctcc aaggatttcc tttaccagac
     2821 aatcccccaa gctcaaaatg gtgatgtaca ggcgtcatac ggaaaatacg tttaccacct
     2881 gtcagtttga aataactgac ttgcatcata acagaagttg tttcaaaaac atacacaatt
     2941 ccgataatca agagagtcca ttcttggtgg agagccatag agatagctgc cagcatccca
     3001 cctagggcca aacttcccac atcacccata aagaccttgg caggcttatg gttaaagatg
     3061 aagaaaccga gcaaaccacc aatcatggca agaatcacta gaagaatatc catctgacct
     3121 tgcacatagg caataactcc ataggcagac aaactaatca caacggaaat actagctaaa
     3181 ccgtcaacac cgtctgtcaa gtttactgcg tttgaaaaac cgactagcca gaaaagagcg
     3241 aagaaaatat agaaaaatcc caaatgaact ggataaccaa agacagacag gatatcgcca
     3301 ccgcgctcat agaaaagata gaagataact ccacctagaa gctgaagagc taatttttgc
     3361 ttaggattaa gcccctcatt gattttacga aagaccttga gaaagtcatc taaaaatccg
     3421 accaagccat acaagaccaa gatgaacaaa atcattccca cattattgct gaattggcta
     3481 ctaaataggg cgaaaaagaa agcaaccaaa acagaagtaa tcaagaaaac caaacctccc
     3541 attgtaggag tcccagcttt tgcctgatgc tgtttgacat cttcatgcat ctgctgtcct
     3601 gtaatttgcg cctttctata aaattggata aaggccggaa ttcctactaa agttagtaaa
     3661 aatgtcacaa ttccagcact gatggaaata aacatattag tctcctaaag ttaatgtaat
     3721 ttttttaatg tccttgatag ctgtgttagc acgaacatct tgcttctgca cagtagagcc
     3781 cgaaccttga aattcaagtt ctatattgag ccacttagca agggtctcag cagtctcctt
     3841 tgtccaacca tacatatctg gaacttcctc tgctttatca gataagataa ggacttgctg
     3901 attcggggca agattcttcc cttcttcagc agaactgttt ttaatcttcg ttcctgttcc
     3961 cacaacgatg ggttgtacaa gattgcgacg caattcttct gctaaatcac caggtgaaat
     4021 atccttgaca ctaggcatag gataaggact ttgttgactt acttgctcca aagctttagc
     4081 tgttgtttga agattgagag agtctttcat agctgaagcc cgctccaaga taggattggc
     4141 aaattctccc aactgaatac ctgaataatg ttcaggttgt tggaccgtca catacaagat
     4201 aaaatcagga ttttcagccg gactcatcga tacagccgag aaaatatagt cggttacccc
     4261 gactagataa ccaccatttt tctcgtcagc aatctgagcc gtaccagact tgagggctac
     4321 attttgccca ggaacagtta cagttggctt gcctgtgctg tggttataca tggttccata
     4381 aaccggatcc gtccctacca aaaccatgtt agtccgagtt agactagctg catctttaga
     4441 aacaggattt cccacaattt ctttttgaga tttccgagca gtttgatcat ttggatcata
     4501 aatggcacta ataaatttag gctccagcat gacaccgtca ttagcaatag ctgtaaaggc
     4561 acgaatcatt tgcgtctggg tcactgaaat cccttgtcca aatgagcttt gcgcaatgtt
     4621 gacaatatta tccgcaggaa gctgaccagc atactcatcc gtcaaaccga aacgggtcgg
     4681 aactccaaat ttaaaacgat taagataatc aagccaggta gcatctccca tcttttgctc
     4741 aaggagggtc atcccaacgt tacttgagtg tgcaaaacct tgagaaaaag tcatcattct
     4801 gccaccagtc aatccttcat taacgtccca atctcgaatc gtggcatctg caatttttaa
     4861 ctcactacta ttaaagactt ctcctcctgg aaaggtatta ttatcaatag cagcagccaa
     4921 catcatcact ttcatagtgg aacctggctc atagttactt tggtaaagga tatcacgcca
     4981 aacaaagtcc tctgtaatgc cttcttttgt atctgcatca aaggtcggtc gttgcgttgt
     5041 tgccagaatt tcccctgttt tagcactgac caaagtcgct gtcatgtact ttccttttac
     5101 cttctcttga aaagcatcca tctgggtttc cataaaggac tggagggggc tggaaatggt
     5161 tgtataaaca tccttaccgt ccatcgttcg ttgggaaact tgttctgttc cgggtacaat
     5221 attacccaga cgatcctttt cataggtaat aatgccgtct gtccctgcaa gaatactgtt
     5281 caaggaactc tccattccag aggttcccag caagctcttg cttccatctt cattttcatg
     5341 gagctgagct aggccgataa aactagaagc aaattgtccg tttgggtaac tacgattggg
     5401 actggttgta aaatcaatcc ccttgacctc tgcagcttcc aattcttttt tgatagacat
     5461 catattggca taggtaatcc catttccctt tgctccaaag gaaacttgct tgagattagg
     5521 ttgcgagagt tgctctctta cataggattc ttccatgtcc aaatacttat gaaagacctc
     5581 tgcaaccttg ttaaattgtg ttttttctac gtaaagaatc ttacccgttg ctgacttata
     5641 gttctcatca atgaccgcat agacattata ggaggttgca tcctcagcaa tcgggactcc
     5701 atttcggtca taaatagtcc cacgtttggc aggaactgta cgggtggttt gatgaacttt
     5761 cttagcttcc ttcgctaaat ctgttccaaa gcgagtgcct gtcccaataa tgaccgcaaa
     5821 attgactaaa aaaatggcaa aaacaaagac agataataaa ctcagacttt ttccaactct
     5881 gcgtctgttt tcagccggcg atttccgatt tttggtcgca taacggatta ctctttttgt
     5941 ccacttcata tcttactccg ctattctaat attttcattg tttaattgca aatcgtgtga
     6001 attggcaatt tctttcaaac gttctgcacg taatagttca ttgacctctt gcttggcatc
     6061 gtccaattcg gttttctttt cctctatctg cgcattgatt tttgtcaaat cattctgcac
     6121 ttgcaagagc ttggtctgca taaaaataat actaatggct acaataagag tggttacagc
     6181 aatggaaaag taaaaagctt tttccacacg cgaaaaccgt ttaagttgca tctgtagtat
     6241 ttgacctgtt ttttccattt tttctgccat ctttttccct cttacttgtg aatttttctg
     6301 gccacgcgca acttggctga gtgcgagcgg ttattggctt ctaactcttc cgcacttggc
     6361 aagattggct tacgggacac caattccatc ttgggcttga gatcatctgg gatgaaaggc
     6421 aagccttttg gaacttcaac tgttgaagct tccttgaaca attgcttggt caagcggtct
     6481 tctaaggaat gaaaggtaat cactgaaatt ctaccatcca gagccaacat atccatagcc
     6541 tgctggatgg actcatctgc cgcccccagt tcatcattga cttcaattcg aatagcctgg
     6601 aaaatctgct tagcaggatg ccccttcttc ttgagttcct tggcaggttt gaccaacttg
     6661 ataatctctg ctaactcagt cgttgtctca atcggcttca cttcacgcgc ttgctcaatc
     6721 ttacgcgcaa tctgtttaga gaatttgtcc tctccatact tgaagaaaat acgaaccaag
     6781 tcatgatagt cataattgtt caccacttca tacgctgtca gactagcatc ctgattcatc
     6841 cgcatgtcca gtggcgcatc ctttttataa gaaaaaccac gctcacgctg gtctaattga
     6901 ggactagaca ctcccaagtc ataacaaatt ccatcaattt cctgaacacc agcttcgcgc
     6961 aaacgtgcct gtaaatgacg gaagttgtcc ttgataaagg tcaccattcc cttctcaatg
     7021 taaggtgcca agcgtttttg cgcattgtca atggcattct gatcctggtc aaaggcatag
     7081 agatggcctt tttcacttaa tttacttaat aaatactcgc tatggcctgc tccacccaaa
     7141 gtcgcatcaa cgtagatacc gtcaggtttt acgtcaagca tatcaatcgt ttcgtggagt
     7201 aagaccgtta catgatgaaa ttcttttgtc atatcttatc tattttacca caaatccgac
     7261 cagcttgcac ttgtcagaca aataggacaa ggagactact atttcttcaa aaaatatgtc
     7321 aaaaatactt gacactttat gtttaaaaga ctataatata gtcaaatata tacgacataa
     7381 atcagaaagg agaccagatg aatcgtgtga aagaatttcg caaggaattg ggtatttccc
     7441 agctcgaact cgccaaggat atcggtgtct cgagacagac tatcaatatg attgaaaacg
     7501 acaagtacaa tccaaccttg gaactctgtc tcaatctcgc ccgcagcctc caaactgacc
     7561 tcaacagtct cttttgggag gaagattttt aaaaaaggag caaactcatg aaaaaagaaa
     7621 ccttcactga aaaactgatc aaacgcacat acggtatttc tggtcccctt gacgaataca
     7681 aacggcgtga ggccgatagt attgggaacc aagtctttat cgtcctcttt tatctgatga
     7741 ttttcggaaa tattattcca ctccttctgg cctataaata ccctcaagaa gtggctctaa
     7801 tctatcctcc tctgatttta gtgattgccc tcatcgcttc tggctatgtc acctaccaaa
     7861 tgaaaaaaac aggcatcaca gtcattgaac cagatatgct gaatgagaaa gaaagcaagc
     7921 aactacacta ccctggtctg aaagcaggtt tgttctttgg tctatggatg ttttttataa
     7981 ctcctcttct cagtatactc atagatgaag gtcaggacta ttttcattct cttctcacta
     8041 taagaaatgg tgtatcaagt attctcggtt ctattttctt cggagcgagc atacagttcc
     8101 tcatctcccg tcgcattgca aaaactaaga aaaatcaaga tgaggattag gaggaaactc
     8161 atgaaaaaag aaaagaaaca gttacgttat cctggtctga aagcaggttc gatttatgga
     8221 acagtgatat tttttataat tccactcatt gataccctaa caagtgaaaa tccaaatttt
     8281 atcagttctc ttctaaatac aaaacatatt tttaaaacta tactgggagc tttctttttc
     8341 ggagtgatga tacatattgt cgactcactt cgtattgcaa gagctaaaaa agaccaggat
     8401 taggaggtgc cttatgaaat cactagctag actactgatc attcatgttt ttatcagtat
     8461 tttccttttc ttcgccctta cttcaggagc tatttctcat acagttttac tactcctact
     8521 cctctttctt cctgcgctca ataaaggact tgagaaaata caatcaaaac ggatacctgt
     8581 cctcaacgca gccctcttct ttctcctcat atcctttcca caacttttaa ccaaccctgt
     8641 ccaatggaaa ttttcaatat tcctagtcgt aaccatcatt tcaagtttgg cctacttcta
     8701 taacttttat caagtagtta aagaagtaga tcaaaaacag ttgatttagg agcttgctcc
     8761 cataatttct cattttatag gcaaataatc ccacctagct tgttctaggt gggattattt
     8821 tatttcttaa cagagattgc aagtcatttt ccttcatttt agaaagtcga ctctttccaa
     8881 ttcacactac aatccaagac ttgttgcctt tcttcttgat tgcgaccttc aatctggtca
     8941 atcaaaatct ttgtagcctg ttgtccttcc tcaaaggagg gctgaaccag cgtcgaaaca
     9001 cttggagaag aaaagcaagt ccactccgta ttgtcaaaac caatcaaccc aacttgcggc
     9061 aagttataat tcaactcttt gataacggta aagactagag gtagggccca acagttaggg
     9121 ataaatacca gagttttttc atcgggatcg atttcttttt gtaaaaattc tttaatttgt
     9181 tccaaattcg tatgcttatc ttcaatggtt agactggcgt gacgcatatt agcatctgtt
     9241 aaagcatcca caaaaccact tgcccgctca atccgagtac tcaaacgact cgtatccgct
     9301 gtaatcaaga gaaaatgttc ataacctttt tcgatacagg actgggtcat gtcataaacg
     9361 gcatcatagt tattggtttt aacccagcta gtccggtgtt catagagctg actatcaaaa
     9421 aagaccattt tcttcttttt ctcatcgatg atacgagaat attttcggaa attagaggtc
     9481 ggctgaataa taaagccgtc tactcccaag agaagcatgc tttcaatata ccggtcctca
     9541 ctctcttggc tgtaattact atttcctatc attacctggt agccattctg gctggcgata
     9601 tcctcaattc ccttaacaat ttggtttgag aaactgttgg taatatcacc aatcaaaaca
     9661 ccgattaatt ttgttcgttt ggagtttaag ctacgcgcaa caatgctcgg tttgtaattt
     9721 gtttcatgaa taactttttc aatcttttca cgtgtctctt gggacatttt ttcatatttc
     9781 ccgtttaggt aaaatgacac ggttgttttc gaggtctgag ccatttccgc aatgtctttt
     9841 atggtcagtt tcttctccaa tctaaaacac ctcctactaa tacttattat aacatattca
     9901 ctattcaaaa tgcctatttc tagcactgca agcgaatcat tctctcattt attttatcat
     9961 atactagaca ttttccacgc atttttgttc cgtcaacgag gcacaatttt tcacctacac
    10021 gaatatcctc gcttaataac agaatcagct tgtctgtttc gtcatttttc acttcaaaag
    10081 ccagagcatt ttccacttca cgatcatctg tctggtagac agaatgacgg atgatttcaa
    10141 aactctcatg cgcaatgatg gtataatcca gcatctgatt ctcaaagaat tggcgcttgg
    10201 tgagtttgct acttctttca agctcattgt atttaggaga aatgatggta tcttccaaat
    10261 caaaatcaac ttcactccat agtctcaact gattgatttt cccatcttga taggtcacat
    10321 ccttgtcaag gataaactga gtcaacgcct catgctgacc ttgacacctg atgtcatcta
    10381 ccaagagcca gacatcctct accaacatga ggatttttct cttgtgaaga taaggcaaat
    10441 caggttctgc tgaccaataa gccccttcaa tataatgcac tccctccctt tctttatggt
    10501 gacaaaacag ggagtgagga tagtattcat attcccagga tcccgtgatt ctttccggag
    10561 ctttcccatc tacaatgcag gtcgaatgac tccaagcact ctttaagaga taacgttcat
    10621 atatctcccg ataagaataa cgcccagcat ctatgaaaat aggttggcct tgatactgta
    10681 agcaaaaact attctcgtca ctatggctat gggcacttcc tagcggacca tttttgaaaa
    10741 atagataacg atgttcatcc ttaatgcaga catgtccaga gtcttcaaag atcatggact
    10801 taggctgcca agctctcctt tcaaattcct gcagtcgctt gaccttttct cgccccagga
    10861 acaagaggct aagcaaatcg actttaacat ccagaccgtt aagaaggtct tccttgttca
    10921 aaaccacagc agacagactc aaaatttctg tcgtttctgt agaatcgcta tcaccaaaag
    10981 ccaaagttcg tccatctaag cctgtcatca tttgaatata ggtcgccatc ttttccagca
    11041 actctcggta actatcttgc aagtctggaa gcaagagaca caaatccagc aaggctttat
    11101 aaacctctac atgatagaga atcgactgtt caaactggct tccatctcct aaaatctgtg
    11161 tctcaatttg ctgtttcaac tcctctgaag caaaatggta agcttcttct agatccatct
    11221 tatctgaaaa gaaataatag atagcaagca tcggaattgt ttgtaaaatc ccccagttac
    11281 taagggtgta cttggcgcga tagtggcttt tcataaagtc aatctgcttt tctagactga
    11341 ccaaaatttt ctctagttct ttctcctcta gcaagtcaaa tttcaagagg agcaagagta
    11401 gtttcaacca agtaaaggaa cgaatacccg tatccaaggt tctagtcatc aaggattgag
    11461 gagaaaattc tctcacctgc tcaatccaat caaatagaaa gaacttgcac ttttgaatat
    11521 agctcttatc tccttctacc acatacccta tcataaactg caagagatat tcttgtcgat
    11581 tgagcatata agcccattct ggatcatctt caaatacttg atcccatacc atcggctgga
    11641 tttgatggat ttttgaacaa ggctccatat cccaaggact atcaaacata aaacgattgt
    11701 ccatcaagcg ttcaagggaa cgcttgactt tctcatagtc ttttgaatag tgggacaaga
    11761 tataatcacg acattggttt ccatcgattc tttcaaaaaa ttgtcttctt tcttctttca
    11821 ttatctatta ccagaaaaag aactacttaa aaagcagttc ttttgtcttt cccattacac
    11881 tttccttttc tacatagatg accacacctt ttgcaatctg caaggagacc aagtcatctt
    11941 tgatagaaat gatttttcca tgaattccag acaataacaa cacttcatca ccagatgtta
    12001 aagaagctaa atactcttgt cgttgctcca tctgtttgcg aagcaacttt tgctgacgaa
    12061 tagaatgaaa gcttgacagt aaaaggggac tcactgccaa gacaatcact attccataaa
    12121 acaatgttgt atccattaag ctataatctt aagccagctt ccgataattc cgatgataac
    12181 tgttaaaata acgagtttat atgttgtcca tttcttttct ttgatcaagt agtaaactaa
    12241 aagtgtaaat agggctggta gaagagctgg agcaacctta tcaagcattc cctgaatact
    12301 tacgatactt tgtttagcgt ctgctttaac ttcccctgca gcaaaggtaa tcggcaccat
    12361 aatcttaaca gatgtcgctg ccaaaccagc aattacggtt acaccgataa tattggcaat
    12421 acgagaaatc gttgccatct gctcgcttag tttatcaatc acagttgttc ctagtttgta
    12481 tccatacaga ccagttgaca atttaatcgc tgttaaaatc gtattcatcg caaggaagaa
    12541 caagattgga ccgacaacca agccttcttg agcaaacgaa gctgcgatgg ttgagaacaa
    12601 tggagctaaa cagaattgag aaagagaatc cccaatacct gccaatggtc ccatcaaggc
    12661 catcttgatg ctacgtgttt cttttgttgg tcgaccattt tccaacatta caagatgcaa
    12721 gctggtaata aaaggcagga agtgtgggtt ggtattatag aattcacagt tttcttccaa
    12781 ggcttggtag aaaccttcct gatcctctcc atagtgtttt ttcaaagcag gatacatcac
    12841 attggcatat cccaaccctt gatagttact atagttaaat ccattttgac aaaagaatgc
    12901 ccgcaaagac gttttaagat aatcacgttt tgttaatttg ttagatccag tcatcgtgtg
    12961 cttcctcctc taccacatga tccgctgttt ttggcttgtt ataaaattca atcaaagcaa
    13021 agatagtacc tacaattgca ataccaattg ttgggatgtt tagataagct gcacaaacat
    13081 atcccaacaa gacaaaggga atcaactctt tcttagccat cactgacaag atcatcgcaa
    13141 aaccgatagc tgggagcatt ttaccagcaa ctgtcaaacc tgtaagtaat accggtggaa
    13201 tgtagtctac gagtttcaac aaggtatcca ttgaaagggc acccaagcaa cccaaggtaa
    13261 atccaataaa ggcaaacaac caaattgttg catttagagt gaacttaaat ttcttcaaat
    13321 tatggttttt caagtgcttc atcgctgttt caggcgcacc agcacgtaca gtgtaggcga
    13381 aagtttgtaa gaattgaatc gccacagcaa tcggagtaga gagggcaaga gccgcttctg
    13441 gactgacttt accagcacta gtgatagcca tcaaggtacc aaagatacca ggtccgattg
    13501 ggtttggtgg aacagtacct ccagcaccta caccgaatcc catataagcc aattcaccaa
    13561 tagctcccat tgcaagagca gtaggcagat cacctagaat aattccgaca ccaaatgaca
    13621 gaacaataca tctattggtg taaattccta acagcattcc actaaaacag aaagctgtcc
    13681 ataatccaat taaaatcgct tgaaatacat taatcgacat aacgatctcc tcttttaaat
    13741 atagtccata atgttgactt gaacagctcc atcatttcct gttggagttg ttttcgtatt
    13801 aaatgttact tgatgagttt ggctcaattc cttgagggct gccttgtcct cttcacccag
    13861 gaagatggag cgtgtcactt gctctttacc aggggcattg tgaatgttcc caatattgat
    13921 ttctttgata gggacaccac cttctaccaa ggttaaagcg tcctttacat cctttacaac
    13981 gataaagatc gtttgagcag gattagcctt gtgaatgata tcaatcacct tttgcaaagg
    14041 gaagaaacgc atggcaactg agtctggcac aactgttttc atcagagttt gttgcatctt
    14101 gtccgtgctt acttcgtcat tggcaacaat gaccgtatta caacctaggt attttaccca
    14161 aagttgtcct tgtccatgaa tcaaccgttc atcgatacgg gtcataataa tatttggcat
    14221 tgtcatattt ctcctcctac caatataggt tccagtcttt gtagaaacgg ataagggctt
    14281 ctaggtaata gtagtcaccc cagatattgc cttcatccac tcctttacct gaatgccatg
    14341 agtacacacc gtggaggaga cttgtcccac caggggtaaa ttgatcattt gcataatgtt
    14401 cgatcaagga acgaagcatg gcatgcatag catgtttata aatatctttg tcagcatcca
    14461 cctctgggag atgttttagc atttcatgaa tcccacagac ggcgatagct gttgctgaag
    14521 aatctcgtga ttgatcacta ccatcattaa aaatcaaatc ccaataggac acatgatctt
    14581 ttggcagacg attcaagaaa taattggtca cacccttaaa caagtcaaag caggactcgt
    14641 cttttaagtg acgataagtc aaaggaatac catagactcc ccatgattga ccacgtgccc
    14701 agcatgaatc atcactatac ccttgtctcg ttacaccttt aaagggttga cctgtctcag
    14761 gatcaaaata gaaggtgtgg aaggacgaag cgtcatcacg gattacatta ttagctgaag
    14821 catagaaatg actttctgca atatcgtagt atttttgatc acctgtttct tgataagcaa
    14881 agaataagag ttggatattg agcaagcagt cgataatcaa acggtaatgc tctttcttgc
    14941 ccaagtctcc ccaagcttga ataaaaccac ctttttcttg atagcgttca atcaacttat
    15001 ctgcagcttt caaggttgct tctctagcct ctccatctcc atttatctta tattcagcca
    15061 tacaagacgg tgtgtacaag aagccgagat catggtgatc caattctact ctcttattga
    15121 cacgatccag gaaagaaaga acatttttat gagcgatgtt tttaaatgca tcctgttgac
    15181 tgtattcata agccaaccac agttctcctg tccagaaacc attggtccat tccgtgttat
    15241 ccatgattgg atagacatta tcaaaggtag ctggcgtcgg gaaatcttcc ttgaaatagt
    15301 caaggttgag ttctaactgc cgaataacct tatcgattgc ctggccgact tcttctttcg
    15361 tcagaagtgg tacttctaag aagcgctcag gcgattttat tttttcaatc gtaacctttt
    15421 ttatcattct tttacccttt aaatacccga ttcgaaatct tcttcctctt cctctgcatc
    15481 cgttgaaaac aattctttac catttacgac tccgccctgg gccgccacta ctgatttatt
    15541 aacaacctca tcaaagctat gagccattct agcaaagact gcttccatta acatggctaa
    15601 gttcaaaccc gagagaacat tcattgtttt ggctggattt tctcccatta tggtagaaga
    15661 aaccttgaat ggcgatcctc ccaagagatc acttaggatt aaaacttctt cttcatttga
    15721 aattgcaagt aagatttttt gcttgagttc atctgctgac attccttcca caaagtcaat
    15781 cgcctccaca ttttcttgat tgcctgcaat caattgtaaa gaactataaa tccctgtagc
    15841 aaaatgtcca tgccctacaa gtacaatttt catcttttct cctttcttgt ttaggtttac
    15901 cggtttactt tatattcccc attgtaatcc tttattttta tcttgtcaat agttttttaa
    15961 aaaaaatatt agcgctttca ttatcttttt aaccatttta ataggcagaa atttcaaaat
    16021 cttccgtttt tttaggaaaa caaacctttt tataaataaa aatatttatt tattgacaaa
    16081 accggtttac tagaatataa tttggttata gagaagtctt aacaaatttg aaaggaagta
    16141 tcaaatgaca aatacatcat tctcaattga gcagttttct ttaaaaggaa aaattgctct
    16201 catcaccggc gcttcttatg gaattggatt tgctattgcc aaatcctacg ctgaagccgg
    16261 cgctactatt gtctttaacg atatcaatca agatctggtc aataaaggga ttgaagctta
    16321 tcgtgaagtt ggcatcgaag cccatggata tgtctgtgac gtgacagacg aggacggtat
    16381 ccaagccatg gtcaagcaaa tcgaacaaga ggttggtgtc attgacatcc tcgttaataa
    16441 cgctggtatt atccgccgag ttccaatgtg cgaaatgagc gccgctgatt tccgtaaggt
    16501 catcgatatt gacttaaacg caccatttat cgtttcaaag gcagttattc cttctatgat
    16561 aaagaaaggg catggaaaga ttatcaatat ttgttcgatg atgagcgaac tgggacgtga
    16621 aacagttagc gcttatgctg ctgctaaagg gggcttgaaa atgttgaccc gcaacattgc
    16681 gtctgaatac ggtggagcca atatccaatg taacggaatt ggaccgggtt atattgccac
    16741 tcctcaaaca gcacctcttc gtgagttgca agaagatggt tctcgccacc catttgacca
    16801 gttcatcatt gcaaaaacac ctgctgcacg ttggggaaat cctgaagatt tgatgggccc
    16861 tgctgtcttt ctcgctagtg atgccagcaa ttttgtcaat ggccacatcc tatatgtaga
    16921 tggcggtatc ttagcctaca tcggaaaaca acctgagtaa aaatagaaag aagatcttat
    16981 gaaaatcgca ttaatcaatg aaaatagtca agctagcaag aatcacatta tttacgatag
    17041 tctaaaagaa gcgacagata aaaaagacta ccaattattt aactatggta tgcgtggaga
    17101 agaaggagaa agtcaattaa cttatgtgca gaacggacta atggctgcca tccttttaaa
    17161 tacaaaggca gttgactttg ttgttaccgg ctgtggtacg ggtgtagggg ctatgcttgc
    17221 tttaaacagc ttccctggtg ttgtctgtgg tctagcagtg gacccaactg acgcttacct
    17281 ttattctcaa atcaatggtg gtaacgcctt gtctatccct tatgccaaag gatttggctg
    17341 gggggcagaa ctgaccctca aattgatgtt tgaacgctta tttgctgaag aaatgggcgg
    17401 tggctaccca agagaacgtg taatccctga acaacgtaac gctcgtatct taaacgaggt
    17461 gaaacaaatc acccacaatg atttgatgac catccttaaa acaatcgacc aagacttcct
    17521 caaagacacc atctctggca aatacttcca agaatacttc tttgaaaact gccaagatga
    17581 tgaagtcgct gcttatttga aagaagtatt agccaagtaa agctattcta aaccagaaag
    17641 gaactaatgg atgacgaaaa tattactgtt tggcgaacca ttaattcgaa tctcaccatt
    17701 agatgccacc agtatcggcg atcatgttgc cagttcgact tattttggcg gatcagaaat
    17761 taacatcgct tgtaatttgc aagccctggg tatctcaacg aaagtcttta ccgcactccc
    17821 tgccaacgag attggagatc gttttctcac attcttgaaa cagcaccaaa tcgataccag
    17881 ttcaatctgt cggcttggcg atcgaatcgg cctctactat ttggagaacg gctttggttg
    17941 tcgtcaaagt gaagttttct acgatcgtaa gcatacgagt atcagccaga ttcggccaaa
    18001 catgctagat atggattctc tctttcaggg gattagccat tttcatttta gtggaatcac
    18061 catagctatc ggtcaagagg tccgtgcgat ccttctccta ctcttggaag aagccaagcg
    18121 ccgaggaatt gtcgtttcaa tggatctcaa tctgagaaca aagatgattt cagtcctaga
    18181 agccaagtat gaattttcta agtttgcacg ttttactgac tattgcttcg gtattgatcc
    18241 tctcatgatt gatgaccaaa atctagagat gtttccaaga gacagtgcta gcctagaaga
    18301 ggtggaaaat cgcatgcgac ttttaaaaga agcctatggt ttcaaggcca ttttccatac
    18361 cctccgatct agtgatgagc aagacaaaaa tgtctatcaa gcctatgctc tggaagaacg
    18421 atttgaagag tctgtccaac taaaaactgc agtctatcaa cgaattggta gcggggatgc
    18481 ctttatatct ggtgcccttt accaactact ccatcattcc tccctaaaaa ctaccattga
    18541 ctttgcagtt gcgagcgcaa ctctcaaatg cactcttcca ggagaccatc tctccacttc
    18601 cgcaactagt attgaaaatt tactggcaaa tgcacaagat atcattcgtt aggagaatta
    18661 catgaccaaa tcagatacga ttattgaact aaaaaaacag aaaattgtcg ctgtcattcg
    18721 aggaaataca aaggaagaag gactacaagc ctcgattgct tgtatcaagg gcggtatcaa
    18781 agctattgaa atcgcctata ccaatcagta tgcaggacaa atcatcaagg aacttgtaga
    18841 cttgtatcag gacgatcaga gtgtttgtat cggtgcaggt actgtgcttg atgccgtaac
    18901 tgctagagat gccattctag ctggagcaaa ttacgttgtt tctccatctt tccatgctga
    18961 aactgcgaaa atgtgcaatc tctacagcac accgtacatt ccaggctgta ttaccctcac
    19021 agagatcacg actgcacttg aagccggtag tgaaatcatc aaactcttcc caggtagtac
    19081 tctcagtcca gcatatatct ctgcagtcaa ggcaccgatc ccacaagttt ccgtaatggt
    19141 aaccggagga gtcggcctaa acaacatccc tcaatggttc gctgctggtg cagatgccgt
    19201 tggaattggt ggcgaactca ataaactcgc ttcccaaggc aactttgacc gcatcagcga
    19261 gattgcccaa cagtatatta cactcagata aaatcataac tacccgtcta acgggtggtt
    19321 tatctcagag ctataagccc aaatcatcag ccagcgccta aagacgctgg ctttcacgtt
    19381 gttcaagcct tattgctctt gactcgtcac ttgcctcttt aagagacttt ggtattactt
    19441 accactatcc ctaaagggat cctcatattc ttttacactc aatttatcta gtgctatagt
    19501 agattgaaac tggaatagta tacctctact tctaaaacat tgttaaaaat cgatttgact
    19561 gtcctgatcg attttgtcct gttcttattt cattttacta tatatcatac tttactagtt
    19621 ctcaaatttt catactcgtg aagaaatcat ccactcgata atttctttaa tcttgactat
    19681 atttcttaat tgtggcttca ttaagcccta ctggacttac ataataacct tccgcccaga
    19741 aattccgatt cccaaacttg tacttgagat tggcgtgttt gtcaaacatc atgagtgcac
    19801 ttttgccttt taaatacccc ataaaacttg aaacacttag cctcgacgga atactgacta
    19861 acatgtgtac atggtctggc attaagtgac cctcgatcat ttcaacacct ttataactac
    19921 acaagcgatg aaatatttcg cctaaactac ttctatattg attatagatg acttttcgtc
    19981 tatacttagg ggtgaacaca atatgataga acacatccac tttgtgtatg ataaactatg
    20041 agtcttttgt gccatatttt ttctcctttc gctttacaat tggattgaat acctttattg
    20101 tatcgcgttt ggagtttttt tggtataacc ttcgacgcgc acctcacgga gcgagacgga
    20161 cttatatagt ggagtgaaat aggatacgaa caaattgatt aggaaaatca aatgaattta
    20221 tagaaatctt ttagcagtta taacgttcta ttctagtttc aaaacgctat agtcacataa
    20281 taatgaagta aaaaaggata agtatcaact tatccttttt taaaagaaaa atccgaagat
    20341 atttggcctt cttcggattt tttctatttt ccacagtttc atgtaattca tctagatgat
    20401 gaacaaatta gttgttcttt cctctacgga atagataaaa tgccccaagt agcaagaacc
    20461 ctagacttgc caagattgac tgaccttctc ctgtctgagg gagattcttt tgatccgaat
    20521 ggttcttttc ctcttcagat ttttcctttt cttttgaatt ctgtacttgt ggctgagctg
    20581 cttgctctag ctttttaaag acttcctgat ctggagctga ttcctgggtt tcaggattat
    20641 agtaggcaat cttatattca tccccttctt ttcgaatggt atagactcca cgtttcaaaa
    20701 cttggaattg gttggaaata gtagagacag aatcatcata tttcacaatg ccccaaactc
    20761 cttgtttagc atcataaaca gactgaaggg tttcgctatt ttcgatgagg ctactttcta
    20821 actcttttat catttgattg aaggtggcac gatccacgtt aggaattagc atatagccat
    20881 aagaatctcc attttgctta tgagcctgac taatcgtaag aaattcattt tcaacttcct
    20941 tgtctgactg tccttcattg atatccttcc aggctccctt ttgcaaagcc ttactcatac
    21001 tgattgaact cttcttaaag aaaaagtaac caatattctt tttcgaatcg gacgattcta
    21061 aaaagacact ttgggtttca ggataatcct tttcttgttc tgtaagggag gcttctttat
    21121 cattgacata gactttatat ggattacttg attccagttg gtgaaatcca tggttgctgt
    21181 cgcattggca tcatctagtt tgctcgttcc aacgaaagca gacggtagaa ctttacctgt
    21241 atcgctatcc gctctcttag catccgtctc tgttgtacca ggcatcttat atggattaac
    21301 tgttggccag tagccatcgc tatagtgact caaatcgcca ttgtaaagat agaacatccc
    21361 atcactcgta taccaaccat gtttattttc cttgttcatg tgttcgtaat tcaaggtacg
    21421 actggaaaag agtgacaagc caaatccaaa ccctttctct gcattgtaca tggctgtttt
    21481 atccatcttg ttaaaggcag ataggtaact tgttcttgga acacttgcga ctcctgcatc
    21541 acttaacaag gattgcatca aactgatatc cttataagtc ttcaaattct taaagacatc
    21601 ataataacta tccgattgaa caatggtctt cacaagactc tgcaaacgtt gtttggtttc
    21661 tccttcagac atatccgcta ttcggtgaat ccctcttagt acttctactg cggccacgtg
    21721 cccctcgcta tttgcacgac tgatcgagcg tccacgactc atatccatca gctctccatt
    21781 caccagcaaa ggagcaaacg atttatcaat ccagtggtac atggtttgca ttttatcttt
    21841 atcgattgga ttcttggtct tttgaatgac tggcaacagt tgagacaggc catcaatcaa
    21901 aacattccca taagcacccg tataggcaac attggtatgg tcgatatagg atccatcttg
    21961 ataaaaacct tcaccttggt ctaccaactt gaacacttgc tcaatcgagc gaatggtaga
    22021 agaaatttct tgatcatcct tacgcagtaa accagctatt acttttactc ttcccatatc
    22081 aactaagttt ccacctagag ccttaaatgg gttatcagtc gtctttcgga aatgttcggg
    22141 atctggtaca aatttttcaa tcacatctgt atatttttta atttcctcat cagagaagta
    22201 ttctttcatc agagacaagg tattgttgat ggcacgaggt gtaccgattt cataatccca
    22261 ccagttccca acaatgctct tttcactatt gtagacatgt ttatgcatcc attccatgga
    22321 atccctgact gttcgaacga cagtttcatc ttgataataa cgagaagaag gattggtcac
    22381 ttgcttggcc atctcctcca atttccgata agtggcagtc agatttgcag acattttata
    22441 atttgaaaat ttttcccaca aataggtgcg gtccgcctga cttgaaatac tagataggct
    22501 atcagctacc tttccttcca attcctggtt taatttggcc atctgttcat ttttagaatc
    22561 atagtattga ttcccagcaa tgatgccatt ccagtcatcc aaacggtctg tgtatgcatc
    22621 cttaacagag gctagaatct tcaaaggaat ctttttcact tccttgccat ctttactgac
    22681 aatgacattg gttgtccctt ccttaagagg ttctaaaatt ccatttttga ctgaagcaac
    22741 gtcaggattt tctaccttat aagtatagtc cgcaagagaa aaaacatgtt tttttccaat
    22801 tggtaaatca atcttttcct caagctgttt atctgtttga gaatcctcag aaagctgggc
    22861 tgctacctct accagctcaa tatccttaaa ggaaacagtc ccagttcctg tttcatagaa
    22921 taactccagc ttgattttat caacatctaa agtcgggcta tagtctgctt caatggtctg
    22981 ccagtccttt gttcctgacg tcgttgcaga attccacaat cgcttgtcct taccactttc
    23041 ctcaatgata cgaactttgg caatcccgac tttatgatct gttttaatct tgaaacgcag
    23101 tttatacttt ttcttagctt caataggaac catacggtga accgctgccc ttaatttctc
    23161 agggcttgag atagtgatag ccccatcctt agcctcaatg actcgagttg aggcatctgc
    23221 agaactattc ttctggtcta cccaagctga ccacccctga gctttgcttc ctgtccacgg
    23281 actgcttccg tcctccgtct gaccaaaatc accattttca actaaatttt ttgtatccct
    23341 ttgctgatac tgaacttcct tctggctttg ctgaatggta ttcgtagtcg tttcttccgc
    23401 tccaactgtc atataatggt ttaataaaaa tcctgataaa acaagtgaag acaaactcac
    23461 aatgagcttc tttgtttttg tttgcatgta tacactccaa taaacatatt gtaaaatcaa
    23521 taggaactaa atctcaaatt agagatttat agcaactaag taaaccggtt taattaaatt
    23581 ataccatttt taaagttatt tgtaaacggt ttctatcata ttgagggctt attcttcaac
    23641 aatatcttcc atccgactcg acgaaaaaag taaaaactgt tacaatgtag aaaaagaaaa
    23701 gaggccctca tgacttcact ttatgatttt tccgttttga accaaaacaa ccaagcaact
    23761 cccttggata gctatcgtgg caaagttctc ttgattgtca acactgctac tggatgtggt
    23821 ttaacgcccc agtaccaggg acttcaagaa ctctatgaac gctatcaaga tcagggcttt
    23881 gaaatattgg atttcccttg caatcagttt atgggacaag cacccggcag cgcagaggaa
    23941 atcaacgcct tctgtagcct acattttcaa accaccttcc cacgttttgc caagattaag
    24001 gtcaacggta aggaagcaga ccctctctat gtctggttaa aagaccagaa atccggccca
    24061 ctaggaaaac gagtcgaatg gaatttcgct aagtttctca tcggtcgaga tgggcaagtc
    24121 tttgaacgct tttcttcaaa aacagaccca aaacaaattg aagaggcgat acaaactcta
    24181 ctataattca caatctcact atgattaggt ttcctttaac ctgatgaata gtgagatttt
    24241 ttgattggct ttgacttaaa tagaaaaaca ccccatgata tgaaacatga agtgttgtaa
    24301 agtctatgtt gtaggtgctt atttcacatt ttcaatgtga ccagtgataa cgaataccat
    24361 acagaatctt catatacact aaacaaatga ctttctaatt atatcaatta gttttggcta
    24421 gtaaatatca tttccaacaa acgccctctc aattccttat cctgatgatg caagatattc
    24481 attaagtcat gagagttttt cgcattgatg aattgattta acaatctatc ttttaattca
    24541 tatggaagag aagctgtctt tagtagtcta aaaacttcat catttaaaga tattgtttta
    24601 ttatctttac attcaaatct agctgtatca ttcttatttg gtaattcaat tatagacaca
    24661 ttcgttcctt taaaatgaat tctatgcctt ctattgcttg gaacgatact agaatctcct
    24721 tgtaatgtta actctaccat ccccatttcc caatcgattg ataatcttgt tttatatctt
    24781 tgaccatttt gatcttcaag catttcaaaa gaatgttgtt tgcctgggaa tacataccaa
    24841 tctacaactt caggtaaatc aacacccata tctatctcag aaccaaccaa gggaatgatc
    24901 gcaccacttt ttgcaaacac aggtatagtc gaaatgtctc tataaacact caacttcaca
    24961 ccacctgtat attttttctc tgaaaagaag tcataccatt caccttcagg gaaccataca
    25021 tccacttttg cagattggaa tgccaagtcc atcttttcta caatgggagc caccattagt
    25081 tctgttccaa aaaagtattg gtttggaaca ttatagctct catcattctc tgggtagaaa
    25141 taatacattg ggctgattaa tggggcacct tcctcgtgtg tctttacatt catagtgtat
    25201 agatatggaa tcatctgatg cctcaaacga aggtatttct tcataatctt agatgttgtt
    25261 tctgaaaaaa accaaggttc tttactatta aaaggacttc tagaactatg taatcgagtg
    25321 atcggactaa aaacaccaaa ctgtagccat ctagtttgca gctcttcgtc ataatctccc
    25381 agcatgtgcc caccgatatc atggctccac caactataac cgatattaga tgctgtcgct
    25441 gtaaaataag gttgaaatct taaggaattc caactaataa tagtgtcccc tgaaaaacca
    25501 acagggtagc ggtggctacc aggacctgca tatcttgata aaatcaaacc accttctgca
    25561 tttttacaac tatcctgata atgataatgg tttaaaagcc atagtggatc caatatgcct
    25621 tgagtccctt gttgccagtc aatccaccaa aaatctactc cctgcttttc tagctcataa
    25681 tgaacatctt taaagtaggc ttccctaaaa gagggattaa aaaaatcaaa aatggcaggt
    25741 tcttctagtt ctacatttaa ccctaatcgt ttggcgactt gaggataagc ttcttcataa
    25801 gcccgtatac catcagcagg atggacattt aaagagagtt ttaactttct atcatgaagt
    25861 tgttgcaata actgttctgg attaggtatt aagtttttat tccaactata tcctgtccag
    25921 ccacttccaa aacgagctgg aatgtcagtt atatgccaat ccatatctaa cacaccgata
    25981 gataatggaa ttttctctgt ttcaaatctg tctattaaat ccaagtattc atccgacgta
    26041 taaggccaat atctactcca ccaattccct aaagcatatc ttggtaacaa gggtgttgaa
    26101 ccagtcaaat ggtaaaagtc tctgattgct cctctataat catgcccata ggcaaagaaa
    26161 tagaggtcaa tttgattttc tctctcaata taaccagact gttcatccca aataaatcct
    26221 tgagaatcat ccaataaggc tataccattt cgactaataa ttccatcttc taatgggatt
    26281 gctccatctg ccttatccag agtccgagct gttcctttta acgtttcaat cgattcacca
    26341 aaataccagc gactaccata tacggcaaaa tttcctttta attctataaa taaattttcg
    26401 gcgttaaatt ctcctttatt aaagtgcaga tgaaaatagt ccgtcataat atctagtacg
    26461 tttgatgtct cgatataatc taacgaaact tggccaaaat ctctattata gataagttgt
    26521 gtagttctat cctcaaaact gccagtttta gagtattcta accttactag cttgtctgtt
    26581 aatacagaga tgcgataaaa ctctccctta aaaattttca atttgtttcc ctccttttat
    26641 ggtagcataa aaacagaacg caccattttt gatgcgtttt tcattattct gaatgcaatg
    26701 ttctatctgt tatatctatg acaaataata gtcaattgaa aaaatgtagt ggacaaaata
    26761 tcttttaaca aaccaagagt ttattaaaga gttatcactt ttcaactttt ctaagcttat
    26821 gcagttgtga aacaaactac ttttaaacta ttaactaaga taggattgat aaataatttc
    26881 aaactcttac tagcaatcat acaatattca agctcacgtg cttttttcct tcctgcttat
    26941 ttcttagaac tgaagaaccc ggatcggtat ataaattatc cggatcaaca tagtcataag
    27001 attcataaca gttgcgcttc attaagtcat ccccagagca agagcttcat ctcgtaattt
    27061 ttcaacatca ctaaccgtag gtcgccatcc ttcaatcata tttgtactta aagcatacca
    27121 aacactctta aaaacggatc ggttttcaaa agctattccc atgattgtca tcttttcttt
    27181 atctatatct aaggacatat gctacctcct ttagatacat tataccatgt ttctatgtag
    27241 cttttaaaaa ttttattttg tttgtcatat ctaagttttc agcatgctta tcctatttta
    27301 taagcctcaa acccaaatat aaaacgcatt ctttttgctt ttttactatt gtatcgtatt
    27361 ctacgataac atactttact ttattgtttt tttaaaataa cagcagttcc ctgtttatca
    27421 actattcgaa ctactttcta ttttgcttca taccctacat agcgaaaaaa tatgaaaaag
    27481 cagagaagaa tatcttaaaa agacctcttc actgctaatg ttaacgctca ttatttaaac
    27541 tatatggatt ctatcatcga gtatactttt ttacttatta gataccttgc tcttctttca
    27601 ccaatttttg atcatataca cggatgaatg gaagatagac taggaatgct gcaaatgcac
    27661 atactagagc aactaataca gctcgaagat ctgctgtccc taagaaagct ccaatcccta
    27721 ctggagttgg ccatggaacc tgtgcgataa ttggcttaat aaagtttaga gaattcgcta
    27781 cgtaataaat agtagcagta accattggtg ctaaaataaa tggtatagcc aaggctggat
    27841 tatagataat aggtaatcca aaaattaatg gttcattaat attaaataag gctggaacta
    27901 cagatgctcg tcctattgct ttaagctgtt cagatttaga ggcaaaagca atatataaac
    27961 atagtcctaa agttgcacca gaaccacctg caattacaaa catattagaa aattcacctg
    28021 caacagcgaa gtgcccgcca gcagcatttt cagccatgtt agcaagagca attggactaa
    28081 caaatgcaaa aacaatgttc gcaccgtgga tacctacaat ccaaagtagt tgagtcagta
    28141 aataaataat cattaaacca atccacgaat tagtcagatt ggatacaaaa ccaaatggaa
    28201 ttgcaatgac tttaaaaaca tctgttccca ttgctacaag aagaccgttg ataaagataa
    28261 caacaaatgc aacaacaaat cccggaacca aagcggtaaa tccacgagaa actccttctg
    28321 gaacagcttc aggcatttta ataacccaat tatgtttaac acacatacga taaataataa
    28381 cagtcacaat tgccataatg attgcggtaa aaatccctgt tgtcccaaaa cgtgcgactc
    28441 catttcccat tgcccatcca tctgcaatta ctgcaccttc ttttagactt gtcacagtct
    28501 tcatcattcc accatcaaaa atgatttgcg gtactgtcat gacaaaagcc atcaaggcaa
    28561 gcaaggcacc attaagagga ttcatattga gttcttcttc ctctgcataa atttttgtca
    28621 attcatatgc aagtgataga acgaaataaa gagatagaga acccatagtc gcatagtttg
    28681 caaccatgta aagtgatgtg aatttatcaa atgaagcaga gaaaatatct gccacaattg
    28741 gccaaaatga gaaagcttgt ggcaaaatac tgaataccaa aaacattgat cctacaatag
    28801 taaatggtac agcagccata cctgcagccg tgatagcacg cactacttta aactgagcaa
    28861 gtttgcccat tggtcccata acatggtttt caagaaaacc aaacaacccg ttttgttgat
    28921 ccataaatag acctccttaa taaaacataa taatttttac tttctaaaga ctagtttcaa
    28981 atacaaatta tactagatca ggattataaa ctaagtgagt tcttttccaa ttggacaaat
    29041 tgttgataag ccttatctgt tcgtttataa atttttttaa ttcttctaat gtctaacaaa
    29101 ctcagaacta aacctaatag aagaactaca aaaacaaata aacgtgctac ttggttattt
    29161 tcaaaaatcg gaaaaagatt cttaaaccaa cttgtccaag ttaaaacaag taatcctatt
    29221 gaaataagca tttgtattct aacaaacatt agtgttattc ccaacttttc tttcctattt
    29281 ccatagagtt taaattgttc aacagttgct aaaatagaaa atactatgag cataatgggg
    29341 aaaataataa taggcgaggg attaataaac tgattcaaaa gccaataaat attcccaaaa
    29401 aagaagagtg ctattgaata acgtagaaga agatatcgat taaaaaaagt attagttaga
    29461 gccatctctc gacgttgttg ttcaatcttt tgtcgttctt ttttatccat atcatttcct
    29521 ccttatataa caacacatat ttagttaact ttcttataaa gagctaacat ttcctttgct
    29581 acttctaata atgtcatagt ggtcattaaa tgatcttgag catgtaccat gataatttca
    29641 attttaattt ccactccact tgcgtattct tgcaagagtt tggtttgtgc atgatgcgct
    29701 tcaagaatta tctcatttga ttgatttaat ttactttctg catcatcaaa actaccttct
    29761 ctcatttttg caaatgcttc atgtatttct gaccttgcat ttcccgaatg caggataatt
    29821 tcaaatgctg caacctgcag ttcctcttga ttcatatgaa cctcctattt tatcttctca
    29881 aatatgttaa taaaatcttc aaagttattg caagatatta gctgattttg caattcatca
    29941 ttctctgtca gagagactat ctttttagtc acagttgcca aaccttcgtt cccatatatt
    30001 gatggagata gaagaaatac tagctggaca tgtgaacttt gattatccca gagtaacgaa
    30061 tctttacaaa ttgcaaccga aacctttccc tctgtaccaa agggctgaat aggatgcgga
    30121 actgcaattt tttcagaaaa aacaactgaa cttaattctt cgcgctgttt aattccataa
    30181 agtaaagatt gttcaaactc atttgattca ccaacagata aactctcaac catcttttca
    30241 agtaaattta ccttgtctga ttcagtacat attaaaaagt tttctttact aaaatactgt
    30301 ctaaagccgt tgttttcaaa tttgttaatc tttgatgatt gtacataact agaaacttgc
    30361 atctgatcca tagcttttct aatcatttcc atctcatcac tcttaagaaa cacactaact
    30421 ttaaaaactg ggatttgaaa atatagattt gataaatcaa cagctgacac tataaaatct
    30481 attcctttaa gtttttcttg attcaattca taatagccta ttacatcaac aacttctact
    30541 cgcttcccaa actccgtttc caaacgattt cttaacattt gggctgcacc aaatcctgtt
    30601 gcacaaatag caagaatatt aaacttagta ctctctttgc tacgttccat agcagctaaa
    30661 aagtgaagac ttacatatgc tacttcatca tctgatattg tccactccaa gaacttgtcc
    30721 atatttgcaa gaatttctct agtcataaag aatatatcac tataattctg tttaatttca
    30781 tctaccaaag ggttatttaa ggtaatccgg ctttctaaac gtacttgtag tgtcattaga
    30841 tgagttatca atccttcaat tagttggaaa tctgaagaaa agttatacat atcatctaat
    30901 cctaaattct gaaatgtttt aaataaagat ttttttaaaa cttcttcaga aatattcttc
    30961 tgattttttt gacattgttg actcttagct aacaaatgca aagtaatgta gtctatttcc
    31021 tgaactggaa attcctgatt tgttacttct cttactttag aaagaattct ttgggcaacc
    31081 tttctctcta ttgcatcatc agtcatctga cagtctatat tttttatttc aaatccggat
    31141 tttaaacgaa tcacagacaa tgctatgtga actactaagt tctgtagtac aaaatcagat
    31201 agttttaggt tggcctcttg gcattcatcc aaaacaattc tagcaaattc ttctaatgga
    31261 acagtttgat caaaaaagtt aaattttaca tagcaatgta ttgttttaaa aaattgattc
    31321 tctaggaaat aatttatgat aaaacgtcgt ttatcacgtt cctcgcctga gacataaact
    31381 cctttattcg ccctactctc aatggacaaa ttatactctg ataacatcac tcgtatcttt
    31441 ctgaaatcat gagataatgt tgaacggcta acgtaaagtt catcagctaa atcatcaaaa
    31501 agaactggaa cttgctcaaa taataattta tttaagataa atactaaacg atcatcacct
    31561 tttgaaaccg cagttttcgt atagtcttct tccagttcat aagtttgtct aaactcctgg
    31621 taagcgcctt gattctcaaa aaatatttga tacccttgac cttgttttga aatcaaccgg
    31681 actccttgaa taatcattgt cttctcaatt aatttcagta cattacggac agttctatct
    31741 gaacaggata aatattctgc cagttctttg cttgtaacaa aacgttcctt attttttatt
    31801 aaaaattgaa ggatatcttt ctctttaatg tttaacacat tcattccctc ctaaaacgta
    31861 tgttttcata tattgaagca tattatacac ttaaatcaat ttatatcaaa ctcaaaacaa
    31921 tttatcttaa cttaaatatt tattgacatt tcatgtgttc atcaaatatt ctcaagaatc
    31981 aaattagcca ttttttcaat tcccattgga ataggaatat aggcttgagg aggtatttgt
    32041 acaactggtt ttcctgcttt agaaccagcc tcttcaaatt gcttaaagta catttttgtt
    32101 tgagggctga caagatacaa atcaaaagct gctgctgcga tagctttccc tccttcagta
    32161 gcactaatag catcaactac aatatctttc ccttttcctt ttagaaactc tgttgttttc
    32221 tgtgccataa gtgatgaaga cattcctgct gcacaaataa ttaaagcttt tgccataata
    32281 ttttctcctt ttcttaaatc caatcaaagc tgtgctaagt tgacttatct gttatctatt
    32341 tttattataa aataaagcgt ttccaatgac aattccctca ttttcctaaa tgatatggaa
    32401 aaaaattatt tatacttcaa tttataaaat aaaattattc ctgagagtag aaatgaaaca
    32461 ctatttgcta aaatcaaagg caagtctcct atacgaatac catgagcaag ccacaatgca
    32521 atatcaataa cttgcataac atacatacct agagcaatag atcctgtgtc ctttgtctta
    32581 actatacgaa aaacttgtgg taaaaagcaa atgttgttaa aattgctgca atacttccaa
    32641 tcatatgtca tcccaatatg ctaaacaaac tgagaataat ctcagtttgt ttatactatt
    32701 ctactgattc accgttagat gaaataactt ccttatacca gccaaaagat tttttcgggg
    32761 aacgattata acttcccttc ccattgtcat ctttatctac ataaataaaa ccataacgtt
    32821 tccgcatttc accggtacca gctgaaacca aatcaataca tccccatgga gtataaccca
    32881 ttaaatcaac accatcttca actacagcct ttttcatttc acgaatatgg gcacctagat
    32941 attcaattct ataatcatca tgtaccatac catctgctgc aacttgatct atagctccaa
    33001 aaccattttc aacaataaag agtggtaagt gatagtggtc tgtaaaccaa tttaacgcat
    33061 aacgtaaacc ttctggatca atttgccact cccattcaga agccttaaca taattatttt
    33121 tcactaaatc ttctgtttca agataatcaa aataaggatt attttcacga tgagagtcta
    33181 tagcaaagga catatagtaa ctgaaaccaa tgtaatctac agtcccacca agtaaatctt
    33241 ctttatcctg gtcagtaaaa tcaactgaaa taccttttcg ttcccaatac ttgaaaatat
    33301 gctcaggata tttacctaaa acatgcacat cagcaaaata ataacgcttc tgcatagctt
    33361 tcattgccat taagatatcc ttaggattgc aagtagctgg ataaattgga cacatcgcaa
    33421 tcatacaacc tatttgaaaa tctggattaa tctcatgacc aatttttaca gctcgtgcag
    33481 aagcaactag ttcgtaatgt gctgcttgat acataattgc ttctctatta tcaccttcct
    33541 catatacaat acctgagtta gtaaatggtg caaaatcttc ctgataattc gcttgattat
    33601 tgatttcatt gaaagtcatc caatatttaa ccttatcttt gtaacgttta aatacgactt
    33661 ctgcaaaacg agcaaagaaa tcaatcaatt tcctattttt ccaaccacca tattcggtca
    33721 ctaagtgata aggcatttca aaatgagata gagtgatgac aggttcaata ccattcttta
    33781 agcattcatc aaaaagatta tcataaaact gtaatccttc ttcattcggc tctaactcat
    33841 caccttttgg aaagatacgt gtccatgcaa tagaggtacg gaagcacttg aatcccattt
    33901 cagcaaaaag tgctatgtct tctttataac gatgataaaa atctatcgcc tcatgatttg
    33961 gataatattt accctctaaa actcccgaag taatttcacg agctactcca tgacgaccag
    34021 cagtcataac atcagcaaca ctaattcctt tgccaccttc ttgccatccg ccttcaagtt
    34081 gatgagcagc aacagcacca ccccataaaa atctatcttt aaaagtagtc atcttttttc
    34141 ctcctgactt tgatactctt attataaacc tcaaaccaaa aaatgaaaac gtattctttt
    34201 tccttattgt taaggaaaga agtaattttt aatggaaata gaacaatatc ttcttgtatt
    34261 ctcgtaatga tatctttacg attttcaata ctttcaaact acaaaaactc tcacaataat
    34321 tctaattccc tgtgtctata aacgacttat cgctttctgg catcccagaa tcatcttcta
    34381 tataacgttc aacttgcatc tgcaagtgat atttttttct taaatctaag attttctgca
    34441 ttgtctttga ttgataatgt ttatctaaag tttcttgatt tatccactga tcaataagga
    34501 gaatagttcc ctctttttca attggtaaaa aatattcgta tttcaagtta cctttttgat
    34561 ttctaatttc ttcaacaagg ccactatcaa gcatttctct tgcaaacttt attgcactat
    34621 ctccatcacc tttataatat acatgaatag tcaatgtcat cttatatcct ccaaaatcat
    34681 ccttcaattt taaaaaaaca agtttagatg aggatctaaa cttgtttttt atgaactaat
    34741 tatctaacgt tttgccatta ctttcaatca cttctttata ccaataaaat gattttttct
    34801 tatagcgatt tatagtcaat tgaaacaaga acaagacaaa agagcctcat aaaaggtatg
    34861 gcaacttggt aatacctttt
//
LOCUS       DAYYYC010000021        34120 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.021, whole genome shotgun sequence.
ACCESSION   DAYYYC010000021 DAYYYC010000000
VERSION     DAYYYC010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34120
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.021"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(59..295)
                     /locus_tag="ACHBV5_001037"
     CDS             complement(59..295)
                     /locus_tag="ACHBV5_001037"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFM9966850.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(308..781)
                     /locus_tag="ACHBV5_001038"
     CDS             complement(308..781)
                     /locus_tag="ACHBV5_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966851.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(799..984)
                     /gene="briC"
                     /locus_tag="ACHBV5_001039"
     CDS             complement(799..984)
                     /gene="briC"
                     /locus_tag="ACHBV5_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HFM9966852.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(1143..1910)
                     /locus_tag="ACHBV5_001040"
     CDS             complement(1143..1910)
                     /locus_tag="ACHBV5_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFM9966853.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKHAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(1907..2773)
                     /gene="accD"
                     /locus_tag="ACHBV5_001041"
     CDS             complement(1907..2773)
                     /gene="accD"
                     /locus_tag="ACHBV5_001041"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFM9966854.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(2810..4177)
                     /gene="accC"
                     /locus_tag="ACHBV5_001042"
     CDS             complement(2810..4177)
                     /gene="accC"
                     /locus_tag="ACHBV5_001042"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFM9966855.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(4189..4611)
                     /gene="fabZ"
                     /locus_tag="ACHBV5_001043"
     CDS             complement(4189..4611)
                     /gene="fabZ"
                     /locus_tag="ACHBV5_001043"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFM9966856.1"
                     /translation="MIDIQEIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(4608..5093)
                     /gene="accB"
                     /locus_tag="ACHBV5_001044"
     CDS             complement(4608..5093)
                     /gene="accB"
                     /locus_tag="ACHBV5_001044"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFM9966857.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(5096..6331)
                     /gene="fabF"
                     /locus_tag="ACHBV5_001045"
     CDS             complement(5096..6331)
                     /gene="fabF"
                     /locus_tag="ACHBV5_001045"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFM9966858.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(6353..7084)
                     /gene="fabG"
                     /locus_tag="ACHBV5_001046"
     CDS             complement(6353..7084)
                     /gene="fabG"
                     /locus_tag="ACHBV5_001046"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFM9966859.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(7118..8038)
                     /gene="fabD"
                     /locus_tag="ACHBV5_001047"
     CDS             complement(7118..8038)
                     /gene="fabD"
                     /locus_tag="ACHBV5_001047"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFM9966860.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(8031..9005)
                     /gene="fabK"
                     /locus_tag="ACHBV5_001048"
     CDS             complement(8031..9005)
                     /gene="fabK"
                     /locus_tag="ACHBV5_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HFM9966861.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(9124..9348)
                     /locus_tag="ACHBV5_001049"
     CDS             complement(9124..9348)
                     /locus_tag="ACHBV5_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFM9966862.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(9408..10382)
                     /locus_tag="ACHBV5_001050"
     CDS             complement(9408..10382)
                     /locus_tag="ACHBV5_001050"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFM9966863.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(10382..10816)
                     /locus_tag="ACHBV5_001051"
     CDS             complement(10382..10816)
                     /locus_tag="ACHBV5_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFM9966864.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(10910..11695)
                     /locus_tag="ACHBV5_001052"
     CDS             complement(10910..11695)
                     /locus_tag="ACHBV5_001052"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HFM9966865.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            12064..13428
                     /locus_tag="ACHBV5_001053"
     CDS             12064..13428
                     /locus_tag="ACHBV5_001053"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFM9966866.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            13431..13802
                     /locus_tag="ACHBV5_001054"
     CDS             13431..13802
                     /locus_tag="ACHBV5_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFM9966867.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            14016..15290
                     /gene="serS"
                     /locus_tag="ACHBV5_001055"
     CDS             14016..15290
                     /gene="serS"
                     /locus_tag="ACHBV5_001055"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFM9966868.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILIK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDASVTIPEALRPYMGGAEVIKP"
     gene            complement(15315..16214)
                     /locus_tag="ACHBV5_001056"
     CDS             complement(15315..16214)
                     /locus_tag="ACHBV5_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFM9966869.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(16324..16872)
                     /locus_tag="ACHBV5_001057"
     CDS             complement(16324..16872)
                     /locus_tag="ACHBV5_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFM9966870.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(17090..18412)
                     /locus_tag="ACHBV5_001058"
     CDS             complement(17090..18412)
                     /locus_tag="ACHBV5_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HFM9966871.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(18503..18591)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(18755..21091)
                     /locus_tag="ACHBV5_001059"
     CDS             complement(18755..21091)
                     /locus_tag="ACHBV5_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFM9966872.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRKVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(21195..21743)
                     /locus_tag="ACHBV5_001060"
     CDS             complement(21195..21743)
                     /locus_tag="ACHBV5_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HFM9966873.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQIYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(21740..22042)
                     /gene="zapA"
                     /locus_tag="ACHBV5_001061"
     CDS             complement(21740..22042)
                     /gene="zapA"
                     /locus_tag="ACHBV5_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFM9966874.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            22129..23013
                     /gene="rnhC"
                     /locus_tag="ACHBV5_001062"
     CDS             22129..23013
                     /gene="rnhC"
                     /locus_tag="ACHBV5_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFM9966875.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVASFV
                     TPDQHAFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISNPISLEE
                     KAEGKYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQG
                     LNFCAKLHFKNTEKAKNA"
     gene            23025..23639
                     /gene="lepB"
                     /locus_tag="ACHBV5_001063"
     CDS             23025..23639
                     /gene="lepB"
                     /locus_tag="ACHBV5_001063"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFM9966876.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            23767..26133
                     /locus_tag="ACHBV5_001064"
     CDS             23767..26133
                     /locus_tag="ACHBV5_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFM9966877.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLKTIQKHITTIEKELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSSISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(26181..27464)
                     /gene="tig"
                     /locus_tag="ACHBV5_001065"
     CDS             complement(26181..27464)
                     /gene="tig"
                     /locus_tag="ACHBV5_001065"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFM9966878.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(28308..29444)
                     /locus_tag="ACHBV5_001066"
     CDS             complement(28308..29444)
                     /locus_tag="ACHBV5_001066"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFM9966879.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(29506..29943)
                     /locus_tag="ACHBV5_001067"
     CDS             complement(29506..29943)
                     /locus_tag="ACHBV5_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFM9966880.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(29945..31900)
                     /locus_tag="ACHBV5_001068"
     CDS             complement(29945..31900)
                     /locus_tag="ACHBV5_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFM9966881.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(31924..33693)
                     /locus_tag="ACHBV5_001069"
     CDS             complement(31924..33693)
                     /locus_tag="ACHBV5_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HFM9966882.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPIANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFFVA
                     ALILHADKSTEDSLEAAQEATQAAKAQSKGQLVSTSVDAVISTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            33903..34112
                     /locus_tag="ACHBV5_001070"
                     /pseudo
     CDS             33903..34112
                     /locus_tag="ACHBV5_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        10153 a         7657 c         6428 g         9882 t
ORIGIN      
        1 caacaataaa aagaaaaagt gtttgataga tatcaaacac ttttttcttt gcctcccact
       61 atctaaaaaa atgataatag atataattgt aaacaaaaat ccagataggt tttgcatgat
      121 tgagaaagtt aaaaaaacta tggcagagaa tcgttaatct cagattgtcg gtagaacgat
      181 aaacaagggc aaaaaagaaa ccaatcagac tataatataa taaactaatt ggatctctgt
      241 gagatagtat caaatggcta atcccaaaga tgatagcaga taggataaca tccaaatagt
      301 acttggacta gggaaagaag gtattcataa aataccctct atcaagagtc tcctcaaaaa
      361 caggaccgat gattacaggc aggacaaaag ataagatagt cgataaaaag gttggttgtc
      421 catttgaaaa aagcacggta aaatactcat catgaatatt cctatgatta atcaaatgag
      481 catagcgtgc ccaaaaatta ccgagaatct gataaaccac ataagttgca aataagtaga
      541 agacaaatga ccagttccag ctctttttct caaagataaa gagcatcttt ttctttttta
      601 acctccaaat taatagaagg aaacttccca ctaatcccat tgttaaaata agagaataga
      661 catcagctcc taaccctaaa atgatcgtca catacaatcc aattgtttgt ggtaaatagg
      721 tagatagtaa aataataagc aaaaatattc caaattgtct tagttttttt gtgtttctca
      781 tcgtactttt ttgaaagatt accctgctcg gaagccgtac ttccaagcat ctatataaga
      841 attaagtgcc ccttgcctca tatagggagc aaattctcta taatataacc atctactata
      901 tccatcttcc caaacagcaa gaccacctga agtttgctcc aagtcctcag ttgaaagaac
      961 tgtaaatgta tttgtacctg tcattgcaag taccttctta aaatagattg ttgtaggctc
     1021 acatttatag tatatttctt tttttgtcta ttttatagcc catctcctca actggcaatt
     1081 tttcgacctg aattacattt ttccataaaa aatgagacct ttctagtctc atttagtcat
     1141 tcttagtatt ttctaaatcg ttgatagcgt tcttccagca actcttctag cggtttttgt
     1201 gaaagtctag ccagctccgt ttggagttct tttttgacac tcttaatcag ttctttacta
     1261 gaaagtccta tttcagaaat caccttatcc accacgtcca tttctaacag ttcatgcgaa
     1321 gtgattttca tcagttctgc tgcttccatg gcgcgagtac cgtccttcca taaaatggaa
     1381 gcaaagcctt ctggactgag aatggcatag atagaatttt ccagcatcca gacacggtcc
     1441 gcgacagcta gagccagagc cccgcctgaa ccaccttcac cgataataat ggcgataata
     1501 ggaactttca ggtcactcat ttccatgaga ttgcgagcga tagcttcccc ttgaccacgt
     1561 tcttccgctc cgacaccagg ataagcacct gctgtattga taaaggtcac aactggacgg
     1621 ccaaatttct cagcatgttt catcaaccgc agtgcctttc ggtagccttc tggatgtggt
     1681 tggccaaaat tccgtttgag gttgtcttgc aaactcttgc ctttttggat accaaccact
     1741 gttacagctt gatctccaag ccaaccaata ccaccaacaa ctgcaccatc atcacgaaaa
     1801 gaacggtcac catgtaattg gataaattca tcaaaaatgc ctgtcgcaaa gtccaaggtt
     1861 gtcaagcgac tctgctcacg cgcttctctg actatttttg caatattcat ctaggactcc
     1921 ctccatgcaa tctgactagg ctagcaatcg tatctggtaa gtctcttctt ttgacaatag
     1981 catccacaaa gccatgttct aataggaatt ctgccttttg gaaatcctca ggcaagcttt
     2041 cacgaaccgt attttcaatc acacgacgcc cagcaaaacc aaccaagctc tgtggttcag
     2101 ccagaatgat atcgccttcc atagcgaaag aagctgtcac accaccagtc gttggatctg
     2161 tcaaaatggt caggtaaaag agaccagcat ttgaatgacg tttaaccgcc gcagagatct
     2221 tagccatctg catgagactc atgattcctt cctgcatacg ggctccacca gaggctgtga
     2281 ataggacaac tggcaatttt tcgacagtcg catactcaaa caaacgagtg attttttcac
     2341 ctacaaccgt acccatagaa gccatgataa agttagaatc cataatcccg agagccacag
     2401 tctgaccttt aataagagca gttcctgtca caacggcttc atgcagacct gttttttcac
     2461 gcatagatgc cagtttcttt tggtaaccag ggaaatgcaa gggatccttg ctttcaatcc
     2521 ctgtaaacaa ttctttgaag gttcccatat caatcgtcaa agccaagcgt tcttgggcag
     2581 aaatacgaaa ggtatagcta cagtgcggac agatacgttc acttcccaga tccttctgat
     2641 agatggtatg cttacagcct ggacactggg aaaataattc atctggaacc tctggcttag
     2701 cttgaggttt ttccctaacc gaacgattgg gattgattcg aatatactta tcttttttac
     2761 taaatagagc cattgattcc ccttttcggt ttaaactctt aaagtcattt tattcttttt
     2821 cttgatattt aggtaagaag gtttccatca agaaggaagt atcataatcc ccagcaatga
     2881 cattgcgatc tgaaatgagg tcaagctgga aatctgcatt ggtctgcact ccttcaatct
     2941 ctaattcata gagggcacgt tgcattttca tcaaggcgtc aaaacgattt tcgccgtgta
     3001 ctatgatttt ggcaatcata ctatcataat aaggcggaat ggtataacct ggataaactg
     3061 ctgaatccac gcgcaagcca actccaccac ttggcagata gagattagta atcttacctg
     3121 gacttggagc aaagttaaag gctgggtttt ctgcattgat acgacactcg atggcatgac
     3181 cgcgtaggac aatatcttct tgcttaacag acaaaggctg acctgccgca atgcaaatct
     3241 gttccttaac gatatcaaca cctgaaacaa actctgttac tggatgttct acctgaacac
     3301 gagtattcat ctccatgaaa tagaaattgc tacttgcttc atcaagaaga aattcaatgg
     3361 ttcctgcatt ctcatagcca acaaactctg ccgctcgaac agcagcagca cctatttcat
     3421 gacgcagcgt ttttccgatt gcaatcgagg gactttcttc caaaaccttt tggttattcc
     3481 tttgaagaga acaatcccgc tcacccaagt gaatcacatg tccatgctca tcacctagga
     3541 tttgaacctc aatgtgccga gctggataga taacccgttc tatgtacatg gcaccattgc
     3601 cataattggc cttggcctca ctagaggcag tttcaaaggc agaaacgagg tcatctggtt
     3661 tttcaacctt acgaatccct ttaccacctc cacctgctga agccttgagc ataacaggat
     3721 agccaatttt ttcagcaaca atcaaagctt cttcagagtt atgcacttct ccatctgaac
     3781 ctggtataac aggcacacct gctttaatca tctgagcacg cgcattgatc ttatccccca
     3841 tcatatccat aacatgacca gatggaccga taaacttgat acctacttct tcacacatgg
     3901 tcgcaaattt ggaattttca ctgagaaatc caaaaccagg gtgaatagct tctgcctcag
     3961 tcaagactgc agctgataga actgcattaa tattgagata agactctgtt gccttgccag
     4021 gaccaataca aactgcttca tctgccaaaa gcgtatgaag agcttcctta tcagcagttg
     4081 aataaaccgc taccgtcgca atccccaatt cacgtgccgc acggataata cgaaccgcaa
     4141 tttcaccacg attggcaatt aaaatttttc gaaacatgga gaacctcctt agttcccaat
     4201 tgcaaaagta aggataccac tggctgcaag cttgccatcc acttcagcct ttgcttcaac
     4261 cacagctatg gtgccacgac gttttacaaa agtcgctgtc ataaccaatt ggtcgcctgg
     4321 tacaacttgc ttcttgaact taaccttgtc cataccagcg taaaagacca gttttccttt
     4381 attttcaggt tttgataact ccaacacacc agcagtttgc gccaaggctt ccataatcag
     4441 aacacctggc ataactgggt attgaggaaa gtggccgtta aagaaaggtt cgttaatggt
     4501 cacatttttg atagcaacaa tggtatcctc gctcacttcc aagacacggt ccactagaag
     4561 cataggataa cggtggggaa gagcttcttt gatttcttga atatcgatca tttgatacgt
     4621 accaatcctt taccaaactc aaccatttct tcgttagaga cgagaatttc cgttaccaca
     4681 ccatccttag gagctgggat ttcattcatg actttcatgg cttcgataat taccaatgtt
     4741 tgaccttttt tgacactatc accaactgta acgaaggcag gtttatctgg tccagcagcc
     4801 aagtaaacca ctccaacaag tggactctct acaagatttc cctcagtagc cacacttgct
     4861 tcagctggag ctggaacttc ttctgctaca gtctctgctg gagcagatgt aggagctact
     4921 ggactcggtg ttgctagaac gggtgctgga gcgacttgag ttgcaacttc aggcacaggt
     4981 ctcgcttcat tcttgctaaa ctgcaactca tccgtcccat ttttataaga aaattctctc
     5041 aaacttgact ggtcaaattg agtcatcaag tctttaatat cgtttaaatt catacttatc
     5101 tattctccca acgtttgaaa gcaagaactg cattgtggcc tccaaaacca aaagtatttg
     5161 aaatagcgta tggaatttct ttctccaagc cttgtccata aacgacatta gcttcgatat
     5221 aatctgatac ttcacttgtc ccagctgtca ttggtacaaa gttatggcgc atagcttcga
     5281 tggtgacgat agcttctact gcacccgcag cccccagcaa atgtcctgta aaagacttgg
     5341 ttgatgatac aggtacttcc ttaccaagaa cagctacgat agctccactt tctccttttt
     5401 cattggcagg agttgacgtt ccgtgagcat tgacataggc tacttgctct ggagaaatct
     5461 cagcttcttc caaggctagt ttgatggcct tgatagctcc ctgaccttct ggatgtggag
     5521 aagtcatgtg gtaggcatca caagtatttc cgtaaccaac cacttcagcc aggatagtag
     5581 ctccacgttt ttcagcgtgt tcaagacttt ctaaaaccaa catccctgaa ccttcaccca
     5641 taacaaaccc attgcgatcc ttatcaaatg ggatcgaagc acgagttgga tcctctgtag
     5701 tagagagagc tgttaaggct tggaaaccag cgatggcaaa aggtgtgata gaagcttctg
     5761 ttcctcccac caacatcaca tcttggaaac caaacttaat ggagcggaag gcatccccaa
     5821 tcgcatcatt tgatgaagag caggcagtat tgatagattt acaaacaccg tttgcaccaa
     5881 aacgcatggc tacattccca gaagccatat ttggtaaagc ttttggaaga gtcattggtt
     5941 tgacacgttt gggtcctttt tcatgaaggc gaagtacctg atcttcaatt tccttgattc
     6001 caccaatacc agatgcaacg ataacaccaa aacgatccct attaagagcc tctacatcaa
     6061 gattggcatg atttacagcc tcttgggctg catacaaggc atataaagaa tagttatcaa
     6121 aacggttggt atcttttttt acaaagtatt tatcgaacgg aaaatcttgg atttctgccg
     6181 cattatgcac atcaaagtca ctatgatcaa attttgtaat gccaccaatg ccgattttcc
     6241 cagttgctaa actattccaa aattcttctg gtgtatttcc gattggagat gttactccat
     6301 aacctgttac cactactcga tttagtttca ttcttttcac ctctagcttt cgctacatac
     6361 ttaagccacc atcaatggca atcacttgac cagttagata atcttggcct gctaaaaata
     6421 ctgtcaaatc tgcaacctgc tctgcctgcc caaattcttt catcggaatc tgagctagtg
     6481 tagcttcctt aatcttatct gataagatag ctgtcatatc agactcaatc attcctggag
     6541 caatcacatt gactcgtata ttccgactag cgacctcgcg tgccacagac ttggtaaagc
     6601 caatcaagcc agccttagaa gcagcatagt tagcttgacc aatattcccc atcaaaccaa
     6661 caacactaga catattaatg atagcacctt ctctggcttt catcatcggt ttcaagactg
     6721 attgtgtcat attaaaggca ccagtcagat tgaccttgag cactttttca aaatctgctt
     6781 ctgtcatctt gagcataaga gtatcttggg taatccctgc attgttgacc aaaacatcta
     6841 ctgaacccag ttctgcaata gcttgatcaa tcatacgctt agcgtctgca aaatctgata
     6901 catctcctga aatgggaacc accttgatac catagtttga aaactcagcg agcaattctt
     6961 ctgagattgc cccacgactg tttaagacaa tgttggctcc tgcttgagca aacttgtggg
     7021 cgatggcaag accaattcca cgactcgaac ctgtaataaa gatattttta tgttctagtt
     7081 tcattttttt cctttcaaaa cttctactta ttttagtcta tttttctaaa agtgctacta
     7141 aactcgcttg atcttccaca tgagctaagt gagcagtttg atcaattttt ttaacaaaac
     7201 ctgacaagac tttccccggt ccaatctcga taaagttgct tatgcctgct tcttgcatga
     7261 ccccaatact ttcatagaaa cgaacgggtt ccttgacctg acgcgtcaag agctgagcaa
     7321 tgtcctcttt ttgcatcaca gcagcttctg tattgccgac taggggacaa gtaaaatctg
     7381 aaaaacttac ctgagctaga gtttcagcta gtttctggct agctggctca aggagagcgg
     7441 tgtgaaaggg acctgacacc ttaagaggaa tcaagcgttt ggcacctgct tcttgcaaaa
     7501 gttcaaccgc tcgatcaact gcaaccactt ctccagcaat gacgatttgt gcaggtgtgt
     7561 tatagttggc tggagtaacc actccaagtt cagaagcttt ttgacaggct tcttcaatga
     7621 cctctactgg cgtattgaga actgctacca tcttgccaga gtcagcagga gccgcttctt
     7681 ccatataggc tccacgctta gctaccaagg caaccgcatc ttcaaaatcc aaggcgccgc
     7741 ttgccaccaa ggcagagtat tctccaagag acaaaccagc aaccatatca ggctgatagc
     7801 ccttttcttg caataaacgg tagatagcaa ccgaagtcgc tagaatggct ggttgcgtat
     7861 agcgggtctg attgagtttg tcttcttccg tatcgatgag ataacgcaaa tcataaccta
     7921 gcacctgact cgctcgatca atcgtttctt taacaatcgg atactgatca tagaaatccc
     7981 gtcccatccc tagatactgg gcaccttgac cagcaaataa aaaggctgtt ttagtcattt
     8041 cttacaactc ctgtccagcg agaggcttct tcttgaattt tcttagcggc tccgtaatac
     8101 aaatctttta ggatttcttc agctgtttct tctttagaaa caagccctgc gatttgacct
     8161 gccatgacag agccaccctc cacatcaccg tgaacaactg ctttggctag ggcaccggct
     8221 cccatttgtt caaagatttc taaatcagga tcttcctgct taaaggcatc tttttcagcc
     8281 agttcaaaat ctctagtcaa ctgattttta atagcacgaa cagcatgacc aaagtgctga
     8341 gctgaaatcg tagtgtcaat atcccttgct tttaaaattt tctccttgta gtttggatgg
     8401 gcattcgact cttttgcaac tacaaaccgt gtccccacct gtacagcctc tgcacctagc
     8461 ataaagccag ccgcagcacc ttcaccatcc gcaattcctc ctgcagcaat aacaggaata
     8521 gatacagctg tggctacctg tcgcaccaag gtcatggttg ttaatttacc gatatgcccc
     8581 ccagcttcca ttccttctgc aataacagcg tctgcaccga ttttttccat gcgtttagct
     8641 aaagcgacac taggaacgac aggaataacg attatcccag cttcatggaa acgttccata
     8701 tacttgcttg gatttcctgc tcctgttgtg acaactttaa caccttcttc aataacgaga
     8761 tccacgatat cttccacaaa gggagataag agcatgatgt tgaccccaaa gggtttatca
     8821 gtcaatgatt tgattttatc aatattggcc ttgacaactt ctttcggggc atttccccca
     8881 ccgataattc ctaatcctcc agccttggaa acagcccctg ccaaatcacc atcagcaacc
     8941 caggccatcc ctccttggaa aataggatag tcaatcttca ataattctgt aatacgcgtt
     9001 ttcatagtgc ctccaacctt ccttgcttac gtaatagttc gatttcacca taatttgaca
     9061 gtcaaactat tacctaaaca agagggagtg ggtttctccc tactccttct actaatattc
     9121 tgcttatttt gcttgctctt caacgtaagc aaccaagtca ccaactgttt tcaagtcatt
     9181 ttctgcttcg atttggatat caaaagcatc ttcgatttct gagattactt ggaacaagtc
     9241 caatgaatct gcgtccaaat catcaaaagt tgattcaagt gttacttctg atgcgtcttt
     9301 tccaagttct tcaacgataa tttcttgtac tttttcaaat actgccatga taggactcct
     9361 ttaaaataaa tagttttttt ataacaatgt gttcaccaca tgattaccta aattgtaaga
     9421 atgagcgtgc cccaggtcaa gcctccaccg aagcctgata gaagaacagt ctggctacca
     9481 tctaaaggga tgagaccttg ttctacacac tctgaaagta aaatcgggat actggctgca
     9541 ctggtattgc catattccat catattggct ggaagtttgg ctcggtcaac accaattttt
     9601 ctagccatct tatccaaaat acggtcattg gcttgatgaa gtagcagata atccaagtct
     9661 gtcacctcta taggagattc atcaatagtc tgcttgatag acttggctac atctcgaatg
     9721 gcaaaatcaa agactgtgcg tccatccatc ttcaaaaatg aatctgcact ttcttgatct
     9781 gaaaatggag aatgcaaacc tgaatgccca taagttaaac actcgctgcg acttccatcg
     9841 ctattgagac tctcagctaa gaaatgctct tgctcgctag cttctaacaa gacaccacca
     9901 gcaccatctc caaacaacac agctgttgat cgatccgacc aatcgactgc cttagagagg
     9961 gtttcactac caatcaccaa gcctttttga aagcgaccag aagcgataaa cttttcagca
    10021 gttgaaagag caaatacaaa tccactgcaa gccgcggtta agtcaaaagc aaaggcttta
    10081 ttagcaccaa tattagcttg aacacgagca gctgtagagg gcatcatcga atctggagta
    10141 atggtagcta ggatgataaa atccagttct tctcctgtta ttccagcttt tgccatcagt
    10201 ttcttagcaa cctctgtagc caaatcactg gtagattctg ttcttgaaat atgcctttgt
    10261 cgtattcccg ttcgacttga aatccactca tcattggtat ccataatctg agccaagtcg
    10321 tgatttgtaa ccacttgctc tggcacataa tgagcaacct gacttatttt tgcaaaagcc
    10381 attatttcaa atcctccaaa aattggtaaa gattagtcaa gcctttaccc atgacagcaa
    10441 tttcttcctc gctcatgcca tcaataattt tttctaccat ggccttgtgg aagcgtttat
    10501 gcagtctatg aatcaagcga cccttctttg tcaaatgcag atgcaccaca cgacgatcct
    10561 gttctgaccg aactcgctca atgtagccct tacgctctaa attgttcaaa cttgtcgtaa
    10621 cagttccaag agttaccatc aactcttttg acacttgact tggagtcaca tctggagcct
    10681 taccgatgac atcaatcgta tgcatttctt tgatggagat atccttaaaa cgactacctc
    10741 tcaagttcac ttcctcaatt acaaggacat tgttaaatat agatgttaaa tattcattga
    10801 ttcgttggta gtccattttt catatccctc cttcttcaaa aaacttttac aatcaaaaca
    10861 tttgacagaa agaattatat caaaattcaa agaatgatgc aagtattttt tattttcctg
    10921 taaatttagg tcttcttctc tccgaatgag ctcgcactcc ttctttgaaa tcctctgttt
    10981 gagctaagga tttctgtagg ttcagttcta aagtagcgta accctgccag tctttaaatt
    11041 ggctctccca aaccaacttc ttaatggcag cataggaatt acttgaagca cgtcttaatt
    11101 ttttaagaag ctgttctctc gtcttttcaa gtttttcagc ttcagaaacg cggtaaacca
    11161 acccccattc tagggctttt tctgccgtta aagcctctcc tgtcatagct aattgagcag
    11221 cacgcgtcac accgatactg cggctcaaga gatgaattcc ccctgcatct ggagccaaac
    11281 caacaccaac aaaggcttgg ataaacttag ccttatccgt cgccaaacag aaatctgccg
    11341 caacagccat attcgctgcg gcacctgcaa cagcaccgtc aacttccatt aaaacaggtt
    11401 tggctatttg cttgatttta taagaaatcg tattgaccaa ctctgcgatt tttgtcaatg
    11461 atggaatatc atcctcatcc actgcccgct tcatctctac caaatctccc ccaactgaga
    11521 agaccttccc attggcattg attaagataa aatgcacagc tggattttct tctgccaaag
    11581 tcagagcttc taaaatctcc tcacacatgg gaatatgaaa accatttgcg acctcaggac
    11641 ggttcaaggt aaggattgcc aagtcctctt caagctgata aataatgtgt tccatcaggg
    11701 ctccttttta ttttataagc agtttatact cttcgaaaat ctcttcaaac cgcgtcagct
    11761 tccatctgca acctcaaaac agtattttga gctgacttcg tcagtcttat ttacaacctc
    11821 aaagcagtgc tttgagcagt ctgcggctag cttcctagtt tgctctttga tttcattgag
    11881 tgttaaatta tttcactgtc aaagtatatc ttttttagga gcagaaagca agaaaaaatc
    11941 gactgaaagt gtctcagccg ataagaaagg ctcgctttag gctagaaagc atcttatttt
    12001 cttcattgaa aaaagccttt ctttctgcta taatcgtata aaatacttac tttaggagtt
    12061 cttatgaaag ttgttaaatt tggaggtagt tctcttgcct ctgctagtca attagaaaaa
    12121 gttttaaaca tcgtcaaaag cgattcagag cgtcgttttg tagtcgtttc tgcgcctggt
    12181 aaacgcaatg ctgaagatac taaggttacg gatgccctga ttaaatacta ccgcgactat
    12241 gttgcgggta acgatattag caagagccaa agctggatta tcgaccgcta tgctgctatg
    12301 gttagtgaat tgggactaaa accagctgtg ctagaaaaaa tttctaaaag tattcacgcc
    12361 ttggccactc ttcctattga agaaaatgaa tttctctacg atactttcct agcagccggt
    12421 gaaaataaca atgccaaatt gattgctgcc tactttaacc aaaatggtat cgatgcacgc
    12481 tatatgcacc ctagagaagc tgggattgtg gtcacaagtg aacctggtca cgctcgcatc
    12541 attccatcaa gttatgacaa gattgaagaa ttgacaaaca ccaatgaagt ccttgtcatt
    12601 cctggtttct ttggtgtcac taaggaaaat caaatctgta ctttctcacg tggaggttct
    12661 gatattacag gttctatcat tgctgctggt gtcaaagctg acctctatga aaactttacg
    12721 gacgttgatg gtatctttgc agcccaccct ggtattatcc accaaccaca ctcgattcct
    12781 gagttgacct accgtgaaat gcgcgagttg gcctatgcag gcttctcagt ccttcatgac
    12841 gaggctcttc ttcctgccta ccgtggaaaa attcctctgg ttatcaagaa taccaacaac
    12901 cctgaccatc caggtactcg tatcgttcta aaacacagta atgatgaatt tccagttgtg
    12961 ggaattgctg gtgactcagg ctttgtcagc attaacatgt cgaaatacct catgaaccgt
    13021 gaggttggat ttggccgcaa ggttctgcaa atcctggaag aacttaacat cggttgggaa
    13081 catatgccaa caggtatcga cgatctttct atcattctcc gttctcgcca actaactccc
    13141 atcaaggaag aagaaatcct gcgtcagttg gttcaaaagg ctaaagtaga tcatgcagaa
    13201 atcgaacacg acctttctat cattatgatt gttggtgaaa aaatgaagag ccacatcgga
    13261 gtgactgcta ctgcgacacg cgctctatct gaaaacaaaa tcaacatcca gatgatgtct
    13321 caaggttcta gtgaagtttc tattatgttt gttgtcaata aagaccaaga gaaagcagca
    13381 attaaagccc tctacaatgc cttttttgga gaaagtaagg aagactaagc atggcccaat
    13441 cacttaacaa aacagtactc ctcagtacga caggcacttc ctacctctct atcgctggga
    13501 aagttgggaa attccttgtc ggagatcagg ctttggaatt ttacccagat gtcaatgtcg
    13561 aacaatttat ccagattcct tggagccata tcaatcagat tggagccaat gtcactggac
    13621 gcaaaatcag ccgccacttc gaagtcttta cagacaaagg aaaattcctc tttgcttcaa
    13681 aagactcagg tgccattctc aaaattgcac gcgaaaaact aggcaatgac aaggtcgtca
    13741 aacttccgac cctgattcag acaattagcc aaaaatttaa aaatctattt gcaaaaaagt
    13801 agaaacttta gtataatcat agcaacggat aagtaggtta tcttcttctt tcagaaagtc
    13861 tgcgggtact gcgagcagat aggagggata ggtgaaattc taccgttagt aacaattaca
    13921 tacacaatca agtgcacacc tgtgaagttg gatggaaccg tggccctgcc actccaacgt
    13981 tttgtcaggc gtgctttttt cataaaggag ttcttatgtt agatatcaaa cgtattcgta
    14041 cagattttga agctgtcgca gaaaaattag ctacacgtgg tgtagatgct gctgtcttga
    14101 atgaaatgaa agaaatcgat gctaaacgtc gtaacatctt gattaaggtt gaaactctca
    14161 aagcagaacg taacacagtt tctgctgaga ttgcccaagc taagcgcaac aaggaaaata
    14221 cagatgacaa gattgctgcc atgcaaaatc tatctgctga ggttaaagcc ttggatgctg
    14281 aattggcaga aatcgatgct aaattgacag aatttacaac gactcttcca aatatcccag
    14341 ctgacagcgt tcctgttggg gctgacgaag acgacaatgt ggaagttcgc cgttggggta
    14401 ctccacgcga gtttgacttc gaacctaaag ctcactggga tctcggtgaa gaccttggta
    14461 tccttgactg ggaacgcggt ggtaaggtaa caggcgctcg cttcctcttc tataaaggcc
    14521 tcggtgctcg tttggaacgt gctatctaca actttatgtt ggatgaacat ggaaaagaag
    14581 gctatactga agtcatcaca ccttacatag tcaaccatga ttctatgttt ggtactggtc
    14641 agtatccaaa atttaaggaa gatacttttg aactcagcga taccaacttt gtcttgattc
    14701 caactgctga agttcctctg acaaactact accgtgatga aatcttagac ggcaaagatc
    14761 ttccaatcta cttcactgcc atgagtccgt cattccgttc tgaggctggt tctgccggtc
    14821 gtgatacgcg tggcttgatc cgtttgcacc aattccacaa ggttgaaatg gtcaaatttg
    14881 ccaaaccaga agaatcttac gaagaattgg aaaaaatgac agccaacgct gaaaacattc
    14941 ttcaaaaact caaccttcca taccgtgtcg ttgctctctc tactggagat atgggcttct
    15001 cagctgcgaa gacttacgac ttggaagtgt ggattccagc acaaaacaat taccgtgaaa
    15061 tctcaagctg ttcaaacaca gaagatttcc aagcccgtcg tgcccaaatc cgttaccgtg
    15121 atgaagcaga tggcaaggtg aaactccttc ataccttgaa cggttctgga cttgcagttg
    15181 gacgtacagt ggctgcaatt cttgaaaatt accaaaatga agatgcttct gtgaccatcc
    15241 cagaagcact tcgtccatac atgggtggag ctgaagtcat caaaccataa aaaataaggt
    15301 ttagctattt ctagctagac cttttttcgt aaccaaatca gataagcacc tagtacaaag
    15361 aataaaatag ttaggcatat aatggtttca gccaatacca ggtaatccag aaatggaagt
    15421 ttcaaaattc cctgagccat cttgagcgag gtcgctgtga taatggttgg gaaggtgagg
    15481 gctgagaagg ctggttgaaa accttgtttt aaaatgttgg gcagacgagt taaaacaaag
    15541 aaaaagaagg attgagaagc caaaatcatg acaatcaaga cccaagtcgg caggctggtt
    15601 cctcctactc gaactagaga agccaagagt agagagaaag gagcacagta gattccttct
    15661 tgtccaagca aggctagtgg gagtggatgt ttctttaaat cgctataaat aaggggatag
    15721 agatagaagg tcaagagaaa accaaaactc aaggtcgcat aggcaatttc gataatacct
    15781 accagaggat aggtcaaggc agccactgct atccccacat agagaaccgt ccaacttgga
    15841 gtggcatgaa ccctccgccc tggacaagca aacttgatgg taaaaccagc aatcaaggtc
    15901 aaatccaaga gaaatgaaaa ccaccaaatc ccttgtgcta ccaaaggaag ataagagaat
    15961 acgcgaaaga cataggtcga taaaatcatc ccagccatag gaaaggttgc cattcctgac
    16021 aaaagagggg gcttggtcaa ttcttgcttg gtttctttcc aattaaagag atgcagaatt
    16081 agaaagtaaa tccataaaac caaaccagtc agactaaaaa gatgggatag aaccggcaac
    16141 gtatctaaaa taagatttcc agctcctgcc aaacctagca aacaacctga aaatactaag
    16201 gggagttttt tcatcctaac ctccaataat catgttagtt tcagtataac ataaaagcgc
    16261 ttaaatgagg atttaaaaaa acgaagtccg cttatttcag acttcatttt actcagatat
    16321 gaattaggca taaggttgca attctggatt aattggtgta ttagctaagt tgttggcata
    16381 gttacagagg attgctaggc tgacaccaaa aaccacatcc aaggcatttt gttgagtgta
    16441 gccagcttct aaaaactcag acaaggcttc atctcctaca cgacccttgg tattgataac
    16501 tgccaaggta aacttagcta gggtatccaa tttaggatct gtttcaattg gagtacgatt
    16561 gcgaagagct tgaatcaagt catcattcat ctggatttgt ttgatggaaa aggctgtgtg
    16621 acctgcgaca cagaaggcac aaccattggt cacggctgcc gtgatttgca ccacttcacg
    16681 ctcaacgggt gtcaggctgt tgcgacggtg gatagatgag acaatttgat aggcttctaa
    16741 aacagtcggg gcattggcca agagaccgat taggttggga atatagccat tgttgtcttt
    16801 ttctactgtt tcaagaattt ctttcacttc tgctggtgct gactctactg tatggatagt
    16861 aaatgttgtc ataagatacc tcttttctta ttattgacac taatattatt ggaaaatctt
    16921 ataaaatcct gattcctaag tttatctaag ataaagcttt attctctcat aagattttcg
    16981 ttgttatatt agtttatcac acttccaatc acttgcataa tatatattat atatcaggct
    17041 gataaaaatt atttataggc aaaaaaatca cacgagctgt gtgattccat tatttgtcaa
    17101 aatacttttt agtttcagca ataacgactg gcgacaagac caagagggca atcaagtttg
    17161 gcagagccat caaggcgtta acgatatctg cgataatcca gaccatatcc aactcgataa
    17221 atcctcctaa caagaccatg agcacaaaaa ccacacggta gagccagata aagcgaaccc
    17281 caaagaggaa ctcaaaacag cgttctccgt aatagttcca acctagaatc gttgtaaagg
    17341 caaaaagtac aaggaagatg gtcaagaggg caggcccaaa gtgtgaaaag actgttgaga
    17401 aagctgactg agtcaaggca accccattca agtcaccact ccaaactcca gttaccaaga
    17461 tggtcaaacc agttagagta caaatgatga gggtatcaat aaaggttcct gtcatggaaa
    17521 tcaaaccttg ctctactggt tcatttgtct tggcagctgc agctgcaata ggagcagaac
    17581 ccagaccaga ttcgtttgag aacacaccac gcgccacacc attttgaata gccatccgaa
    17641 cgctagcacc agcaaatcca cctaccgcag caaggggact aaaagctgag gtaaagacta
    17701 aagcgattgt gccagggatt tttccgatat taaagaaaat aactgtaaga gttcctaaga
    17761 tataaatgat ggccataaaa ggaacaacag tagttgaaac cttagaaata gacttgagtc
    17821 caccaaagac tgcaatcgct acaaagacag acaagacgag agctgtgatg gctggcgaaa
    17881 tcgtcgttgt attttggata gattctgcaa tcgagttgac ttgggtgaag gttccgattc
    17941 ccaagagagc aaccaatact cctgctactg caaacaaaac agcaagtggt cgccactttt
    18001 ctcccatccc tagaaggata taatgcatgg gacctcccgc tactgcacca tggtcgtcct
    18061 tggtgcggta tttgatggcc aagagtcctt ccgcatactt ggtagccatt ccaaagaaag
    18121 ccgccatcca catccaaaat agagctcctg gtccaccaac cttgatagcc gtcgcaactc
    18181 ctatgatatt tcctgttcca acagttgatg ccaaggctgt acacagagct gcaaaactgg
    18241 atacatcacc atgtccctta tcctggataa aaataagctg aaaagccttg ggcagacgca
    18301 aaacctgcaa gagtcctagc cgaatagtta ggtaaatccc tgttccgacc aataaaatca
    18361 agaggggcgg tccccaagca aaagcatcga ttgatttaag caattctaac atttccttct
    18421 cctatcgttt caaccccaaa agaaagagca catgcaagat acatgtactc tggaatgctt
    18481 agataaatgc taaaaagcgg tctatcctag ctctgtcctt ttacctgaga gtttgagcag
    18541 ttgcctgcct tgccccttcg gtgcctttac ggtctctcca gagttccgtc catttacagt
    18601 catggaaaat caaacgattc cccacttcta ttaaacttca ttcggtgttg gtatttaatt
    18661 gattctaatt ttacaaaaaa tgttggcttt tgtcaatgtg tttattagta aaaattagtt
    18721 caacagtttt tactttataa agtccagaat actgctatcc tttaaaagtg acaatagtcg
    18781 caccactgcc tccagcattt tgtggggcat agccgaaact cttgacatgt ttgtttcttt
    18841 gcaagtattt ggtaactcct tcacggatga ctcctgttcc gataccatgg atgatatcaa
    18901 cttgagccat attgttaagc aaggcttggt cgatgaaggt atctagctca ttcatggctt
    18961 cttcatagcg cttgcctcga agatccagtc tagcttgagg tcctcgccca gaagttcgtt
    19021 tcacaacatt gacctgtttc ttcttgactg gtttttcttg ctgggcttga acaagatcaa
    19081 actctttctc ttccaaggtc atcttaatca agccaacttg ggcttcccag cggccgtcct
    19141 tgagttgact ggtcaaggta ccacgctgac cataactgag aaccacgata tcatctccca
    19201 cctttggagc tcgttttttc ttggcctttt gaaggacctt gtttttagac aagtccactt
    19261 tttcaggagc caattttttc aacttggcct tggcttcaat gatttcgtgg ggcttgagtt
    19321 gggatttact gtggagattt ttgagaatct ggtcactttc acttagggcc atatccacaa
    19381 tctcagcagc ctgttcacgc gccttgttaa gctcggtttc cttttcacga ttaagctcgt
    19441 tgtagagttt ttttagcgca cggttcatct tgagattttc ttgctccacc tcacggatat
    19501 tgtccaagcg tttgcggctt tccagcgtct gctcttctaa ttgctcaatg atacgattga
    19561 cgtcattgtc ctgatcgatc tgctgactgg catctcctac gataacttca gataggccta
    19621 gacgtttggc aatttcaaag gcattacttc ggccaggaac accctgcata aagcgatagg
    19681 tcgggcgaag agttgcagta tcaaactcca tactggcatt ttgcacaaag gctgtctcaa
    19741 taccgtaggc cttgagttct ggatagtggg tcgtcgccat ggtcttgatt tgacgcaggc
    19801 gaaggtcctc cagaatagcc atggcaaggg ctgctccctc ttggggatca gtaccagccc
    19861 ccaactcatc caaaagtaag agtgaatgtt ggttgacctt gccaagaata tccacgatat
    19921 tggtcatatg gctagagaag gtagacaagc tctgctcaat agactgctca tctccaatat
    19981 cagcaaaaat ttcttcaaaa ataccaacac gacttccctt gtctgctaaa atcggcaatc
    20041 ctgactgggc catgacctgt gtcaagccca gagttttgag catgatggtc ttcccacctg
    20101 tattgggacc tgtaatgaca atagctgtta aatcttgacc aaaatagaca tcatttgcga
    20161 cggcattttt gaccaaagga tggcagacat ggagcagttg aatctcttga ttttctgaca
    20221 gctgaggcac gactgcttgt ctttcttgga taaatcgaac cttggcacga atcaagtcca
    20281 gatgaccgat aatccaagca tcattagcaa tctcagccgc atgagggcgg acacgctcag
    20341 aaatttcttg gagaatgcga agcatttcat agcgctcatc tgctcgcaga ctagcaattt
    20401 cttcgctcag tttgactacc tcacggggtt cgatatagac ggtgtttcca ctagcagaaa
    20461 tatcatgaac gacacctgca atcttattgc ggtaggtgtt tttgactggt aaaaccttac
    20521 ggccatttct gctagcaaca attccttccg tcaacatctg cgctttttgc ttgagcaagt
    20581 cttgtaaaac atcgcgtacc tgactctcgc tatcatgtat ttttcgacgg attcgcgcca
    20641 attcttcact ggcaaaattt tcaatgaaac ccgcatcatt aaaggcctga agatttcctt
    20701 gtaattgcgg aaaatcatgt aatttctcaa accaaagggc taattcttcc aagctgacat
    20761 tttccagatt ggcgtaaaaa ctttgaagtt ctcggctggc aagaagcacg cgtttcaaga
    20821 gtaggaactc ctcgatattg agatccgctc ccatctccaa cctcttgcag actcctgcaa
    20881 tttccttagt tgagagaata gtaaaatgcg gttgctcgac gaaaagagcc tgcatttcct
    20941 tcatctcagc aaaagcctgt ttgattttat ctgctttggc agtcggagcc agttgtctca
    21001 attgctccaa gccctgctcg gtcaacaaat gaggctcaaa caaggccttg accttatcga
    21061 actctaatgt ttctaatatt ttcttattca tctttatttc cttgtctttg aatgtctagg
    21121 tgtggtaact ttttacattc tgatagattc aagtcaaatc tgtaaacaaa gggctaggaa
    21181 aactcctgcc ctttttatcc gattaaattt gtcacccaga tttgtttgag ccaactggtt
    21241 gttatcggta tgctctggat gatgtgtttt gcgacgatac tcttttcaag aggattttgt
    21301 ataactgcca tggggatggt cgccaagatt gtcaaggcca tttgcaagac aaataaggtc
    21361 accaacatgg acaagatacc tgctgaaact tggaacaact taccacccag ttttttgcta
    21421 ggaatcaagt gtaagagaag accaagcaaa cgaccaatgc tatagacaat cccaaataca
    21481 agcaagtagc cgatacctgc ataaaagacc ttatccagct gaaagagttg atccgatggg
    21541 aaaaagaaag tcccctgacc ttcctgcgaa tttgcataag ggagcaataa atggaattgc
    21601 tctccaagcc ccttataaaa ctggccagcc ataaaagccg atgccatggc tgaaatcagg
    21661 taataaatct gtaagagcag gcctctccga tagccgatat aaaatcccca aaccaagacc
    21721 aatagaagaa ggaatgaaat cataaggaat cctcaatctt gctctgttct tgcttacaag
    21781 tcacaagctt gtgacggagt tcttctagct cttgctcctt atcgtcaaat tcaatctcac
    21841 ggctgagctg agttgataaa cagttgactg ccaacaaaag agcgattgtt tcatcatctg
    21901 cgctaggcat ttgttcttta attgcttggt atttttctgt cgcaacctta gcgatttcct
    21961 ccataaaaag gttatcatgt tcacttgtca aggttaacga ttttttcccg aatgtaaatt
    22021 tgaatcgatt tagatttgcc ataaaattca cctcacgata ttataccaaa attcgctaat
    22081 tttgtcagtt tttacaaatt ttactgcttt tgtggtacaa tagaaactat ggcaagtatc
    22141 acactcacac caagcgaaaa ggatattcag gcttttcttg aacactatca aaccagtctg
    22201 gctcctagca agaatcccta tatccgctac tttttgaaac tacctcaagc aacggtttct
    22261 atctatactt ctggaaaaat cttgcttcag ggtgaagggg ctgaaaaata cgccagtttc
    22321 tttggctatc aagctgtaga gcaaaccagc ggacaaaatc ttcctttgat tgggacagat
    22381 gaggtaggga atggttccta ctttggtggg cttgcagttg tggcttcctt tgtcacacct
    22441 gaccagcatg ccttcttacg aaaactcggt gtgggagatt ctaagactct gaccgaccaa
    22501 aagattcgtc agattgctcc tattctcaag gaaaaaattc agcaccaggc actccttctc
    22561 tcacccagca agtacaacga ggtcatcgga gaccgctaca atgctgtttc ggttaaggtt
    22621 gccctccata atcaggctat ctatctcctc cttcaaaaag gtgttcagcc tgagaaaatt
    22681 gtgattgatg cctttaccag tgctaaaaat tatgacaagt acttggcaca agagaccaat
    22741 cgtttcagca atcctatcag caatcctatc agcttagaag aaaaggctga gggcaaatac
    22801 ttggctgtcg cagtttcttc tgtcattgcg cgtgatctct ttctggaaaa tcttgaaaat
    22861 ttgggacgag aactgggtta tcagcttcca agtggagctg gaacggcttc tgacaaggtg
    22921 gctagccaga ttttgcaagc ctatggtatg cagggactca acttctgcgc caaattgcac
    22981 tttaaaaata ctgaaaaagc gaaaaacgct tagaaaggta agttatgaat ttatttaaaa
    23041 atttcttaaa agagtgggga ttattcctcc tgattctgtc attactagct ttgagccgta
    23101 tctttttttg gagcaatgtt cgcgtagaag gacattccat ggatccgacc ctagcggatg
    23161 gtgaaatcct ctttgttgtt aagcacctcc ctattgaccg ttttgatatc gtggtggccc
    23221 atgaggaaga tggcaataag gacattgtca aacgtgtcat cggaatgcct ggcgatacca
    23281 tccgttacga aaatgataaa ctttacatca atgacaaaga aacggacgag ccttatctag
    23341 cagactatat caaacgcttc aaggatgaca aactccaaag cacttactca ggcaagggct
    23401 ttgaaggaaa taaaggaact ttctttagaa gtatcgctca aaaagcccaa gccttcacag
    23461 ttgatgtcaa ctacaacacc aactttagct ttactgttcc agaaggagaa taccttctcc
    23521 tcggagatga ccgcttggtt tcgagcgaca gccgccacgt aggtaccttc aaagcaaaag
    23581 atatcacagg ggaagctaaa ttccgcttct ggccaatcac ccgtatcgga acattttaag
    23641 agacctaaga ggccgagaat caccaatctc agcctcttct tctatcgtga gaaaatgatt
    23701 ggtaactatc taaacttacc agaacagaaa cacctcaact ctcacctatt catgcaaagg
    23761 aattttatgg aagtttattt ttcaggaacc attgaacgga ttatttttga aaatcccagc
    23821 aatttttatc gcatcctcct cctagaaatc gacgatacgg acgcagagga ttttgatgat
    23881 tttgaaatca ttgtcacagg aaccatggct gatgtaattg agggcgaaga ctatactttt
    23941 tgggggcaaa ttgtccagca ctccaagtat ggagaacaac tgcaaatcag tcgttatgat
    24001 cgcgcaaaac caactagtaa gggcttggtc aagtactttt caagtagcca tttcaagggg
    24061 attggtctca agacagctca gaaaatcgtg gatacctatg gcgaaaatac cattgacgaa
    24121 attttgcaac acccagaaaa gttagaaggc atcgcaggac tctctgccaa aaatcgcgag
    24181 gctttcgtct ccactctccg tctcaactac ggaacggaga tggttttggc caaactagcc
    24241 aactacggca ttcccaacaa actagccttt cagattcaag acttttacaa ggaagaaacc
    24301 cttgatgtgg ttgaaaatta tccctaccag ctggttgagg atatcaaggg tttgggcttt
    24361 accattgctg accaactagc tgaggaacta ggcatcgaaa gtcaggctcc tgaacgcttc
    24421 cgcgccggtc tagttcacag tctttttcag gcctgtatgg aaacagggga cacctatgtt
    24481 gaagcacggg atttgctgga acaaaccctt actctccttg agtcttcccg tcccgtggaa
    24541 ctagacccca gccaagttgc ccaagagctc tcctacctga tcgaagaaga caaggttcag
    24601 cagattgata ccaagatctt tgacaacagc ctctttttcg ctgaggaagg catccgcagt
    24661 cacttggttc gtatccttga aaaaggaaaa cagaagagtc atgatttaaa aaccattcaa
    24721 aaacatatca ctactatcga gaaagagctt ggaattgagt atgataacat tcaaaaacag
    24781 gctatctgtg atgctatcca gaataaggtc tttatcctga caggtggacc tggtactggt
    24841 aagacaactg ttatcaatgg gatcatcgct gtttacgccc tgttagaggg acttgacctc
    24901 aggaagaaaa gcaacctgcc cattcttctt gctgctccaa ctggtcgagc tgctcgtcgc
    24961 atgaatgaat tgacaggttt gcctagcgcg accatacacc gccacttggg aatgacaggt
    25021 gacgatgata ccagtcatct ggaagattac ctagatgctg actttatcat cgtggatgaa
    25081 ttctctatgg tggatacttg gctggccaat caactcttct ccagtatctc ttctaacagt
    25141 aagatcctca tcgtaggtga cagtgatcag ctaccttctg tcagtcctgg acaggttcta
    25201 gcggatctgc ttcatattcc tttgattcct cagactcgct tggaaaaaat ttatcgacaa
    25261 agcgaagaat caaccatcgt caccctagct agtcagattc gacagggcat cttgccagct
    25321 gatttcaccc aaaaaaaagc tgaccgttcc tactttgaaa ttgctagtgg ccatattcct
    25381 gccaccattg aaaaaatctt aggtgccgcc ctcagaaatg gtattcctgc ccgtgatatc
    25441 caagttctgg ctcctatgta ccgagggacg gcagggattg atgctatcaa tcagctcatg
    25501 caagacctgc tcaatccccc acaaaaagat caactcagtt ttgaagctcc tcagtgccac
    25561 tatcgtaagg gagacaaggt cattcatttg gttaacgatg ctgaaatcaa tgtctttaat
    25621 ggggatttag gagctatcac agacctgatt cctggtaaat acaccgaatc gaaacaagac
    25681 gagattgtca ttgattttga tggtaatgaa gtctcttacc cccgtaacga atggtacaag
    25741 attcgcttgg cctatgccat gagtattcat aagtctcagg gaagtgagtt cccagttgtc
    25801 atcctaccga ttactagtgc tagccgacgt atgctggagc gaaatctcat ctacacagcc
    25861 attacacgtg ccaaaagcaa actcatctta ctaggcgaat tacaagcctt cgactatgct
    25921 acccaacaca tcggaactgc ccgaaaaacc tatctgattg aacgcttcag tgatctactg
    25981 gagaatgttg aagaaaagca acaagctgtc tctgaaacag tcacatcaag tgcctctgaa
    26041 caatcctaca tcctaaccga agaaaactgg gacagcattc cagccatgat tgggattaca
    26101 gacacagacc tcaaagagat ttttggaaaa tagtacatca gaaaacccac caattcaggt
    26161 gggttttctg tttattaaga ttattttact gttgctgtgc ttgtgatcaa ttcaacagct
    26221 tttttgatag tgatatcatg tttcaacatg tcagctgaaa gcaagttttg aacttgtgca
    26281 acttccatgt tgtagtctgc tgccaattgc tcaacttctt tttggatttc ttcttctgaa
    26341 gcatcaaatc cttcagcttt ggcaactgct tcgataacaa ggttagtctt agtacgtgac
    26401 tcagcttctg cttggtattg gttgtgaagg tcttcttgag tagttccagt gatttggaag
    26461 tacatgtcag ggttgatccc ttgacgttgc aagttcccaa ggaattcatt tactgaacgg
    26521 tgaacttctt catggatcat ttcttctgga agttctacga tttcagcgtt ttctacagct
    26581 gtatcaattg ctgcaccttc aactgcatct ttgtaagctt cttctttagc agcagccaat
    26641 tctttgcggt atttttcttt caagtcagca agtgtttcaa cttcttcatc aatgtctttt
    26701 gcaagttcat cgtcaagagc tggaacttct ttagctttta cttcgtggat agttgtcacg
    26761 aatttagctt ctttacctgc aaggtcttct gcttggtagt cttctgggaa tgttacgata
    26821 acatcaacgg tttcgccagc tgagtgacct accaattggt cttcgaaacc agggatgaat
    26881 tgacctgaac caagtccaag tgagaagttt tcaccttttc caccgtcaaa ttcaacaccg
    26941 tcgatagaac caacgaagtc gatcacaaca gtgtcgccgt tttcagcagc agcttccttg
    27001 ataaccaatt cagccaggtt gttgcgttcg cgttcgatac gctcttcaac atcagcgtca
    27061 gttacttctt tttctacatc aactgatact tcaaggtttt tgtagtcacc caattttact
    27121 tcaggttttg taacgacttc agcagcgata acccagtctt gacctttttc cattgaagtt
    27181 acgtcaattt ttggttgggc aaccacttca agaccagctt cttttacagc tgcttcataa
    27241 gcgtttggca aaagagcgtt cataacgtct tggtaaagtg attcttcacc aaatttttta
    27301 tcgaagatag gacgtggaag gtgaccttta cggaaacctg gaacattaag agatttcttc
    27361 actgacttga agacacggtc caattctggt ttgatttggt cttgagagat agtgaaagtc
    27421 aagacaccac ggtttgtttc tttgttttca aatgatacag acattctgtc atttctcctt
    27481 aaaatttttt aaatacagtc tattataaca ttttctataa ataaaatcta gactaatgca
    27541 gccaattata gacaacaagc ctttttccta actaaaacac tcataaagta tagacaattt
    27601 tagactactt tggatatctt ttggttagtc attttccaaa actaatttat ctaatttttc
    27661 agttatatag tagattgaaa ctagaatagt acacctctac ttctaaaaca tttttagaaa
    27721 tcgctttgac tgtcctgatc gatttgtcct gttcttgttt cattttacta tatagatcgc
    27781 attcgaaaga attcgttcca aaattgcttg gttcgttctt ctcttggacg actaaagaat
    27841 tgatgggcat tatttttttc aacaattttc ccaccgtcca taaaaataac atgatgggct
    27901 acatctctag caaaacctat ctcataaagc tgatcaaaaa ctcaatctga ggagaaaatc
    27961 caataaggct ttccataata aaggacatcc tatcaagatt tttgaacacc cgataggctg
    28021 cctttttccg attttgaaga ctttttgtcc agcttctttt accttataaa taacaacaaa
    28081 aatcaaagac aagctagaaa gattaccgca gataactcaa acagtgtttt gaggttgcag
    28141 ataagactga cggagtcagc tcaaagcact gctttgaggt tgcagataag actgacggag
    28201 tcagctcaaa gcactgcttt gaggttgtag atagaactga cgaagtcagt aacatatgcc
    28261 taagacaaag cgatgctaac ctgatttgaa gagattttcg aaaaatatta aatatactct
    28321 acaatttgct caatcaattc ttggtcgtct aaacctgtaa cttgtataac aacatctttg
    28381 actgattgtt tagccaacaa ttcacctaat cgaatacttt cttcatcatt tacatcgcga
    28441 tagtcaaagg catagccaac tgttttaagt aggtttttat atgacaaact gagttctttc
    28501 aattcacgta tcggccggat gaatcgttca ttatagccta attttcggat tggagtacga
    28561 gctacgcgac taacctcgtc cactatgaaa gggttttcaa accgttctat aatgactttg
    28621 tgataattct ccaattcttt tttatcaaag ttccatttgg caatcaagag actccgaatt
    28681 tcagctaata cagattcaat ccgagattta atattaggat tttgaagagc ttccaaaatt
    28741 gtcttggcac cataatgcgc accaatgtaa gctgaagttg catgtccaga attgactgaa
    28801 aaaagttttc gctcaataaa gggttctaaa tcttcttcat aatgcacatc ttttagacgt
    28861 aaatctggat ttttaagacg cttggtttcc acgacccatt cattaaaggg ctcgaccaca
    28921 acaaaaaggg aatcttcgtg actttgtgct ggaacaatcc tgtctactgc agcatttgga
    28981 aaacctatgt agttatcagc aaatgtcaaa ccttccggac ttaaatattt cttgacttct
    29041 tgataaagaa attgagaccc gccaatcata ttttcacagg ccataacatc caatacctgt
    29101 gtattccctg caactcggcg agcttcgatt cctttggcta gaagttcagc gataaaaggg
    29161 agtatattag gtccgattgc agtagtaata atatccgtct tttgaatcgc ttcaatgact
    29221 tgctcaggat gttctttgct attaattcca gccacattag ttacttctat acgagactgt
    29281 cctttctgtg caatttcaat ttcatacttg cccttttcat ttagagcatg aattatctga
    29341 ttattgacat ccacaaaatc aatatggaaa ccatttttaa atagaatttc acctataaaa
    29401 ccacgaccga tattaccggc accaaaatga acagaatgtt tcattcaatt tctccttttc
    29461 ctatttgagg gacatatata ctagatggca aatgacgaaa ttcaattatt caacagcatc
    29521 aaataagcgc aatacttcct cttttgactg agcatcggct aatttaagaa cattatctac
    29581 atctgcacag aagatagaaa ttttctgaat aatttctaag tgttcattac caataccagc
    29641 aataccaaaa agaaccgttg ccacttgagg gttagataca ttcccaaaat caacccctct
    29701 agggacttga acgactgtaa taccagactt gaggacatcc ttttttgctg catctgttcc
    29761 atgcggtatt gcgataaagt tacccatgta aacagatagc tctttatctc gctcaatcat
    29821 ggcttcaata tagtcttcat taacatatcc accctcataa agaacttgcc cacaataaca
    29881 aatagcttcc tccttgttag aaaattgttt attaagctta atcaaatgtt tttcaagttt
    29941 catattagtt ctccaatttc ttaatttttt cgttaaaaat agtatttagc atctgataaa
    30001 taatggattg atttcccgtc ttgtaaatct ctgtataaag atgattttca ataatcgact
    30061 gactaatagc tgtcattaaa tctctcgctt cctcgctagc ttctttagac attagcatta
    30121 gcagacacct tttgacctct tcttcctctc gtttcattga caatgcggag ataggtagtt
    30181 tgagttcaaa catagtaaaa ctatttgttg ttactttgct agactgacta tgtaaaagca
    30241 ccagaccagt attaggaata gccataggac tattctggaa gtgagataac aattttcttg
    30301 ttaggtaatc tctgtcactc acattcttct gatattggat gatttgttct accgtgtgct
    30361 caaatgattg attattctcc aattgaacca actcgaattg actcaaaagc tgactactag
    30421 atattaaata atcttgcaag tcataacttt tctctggagc gatagcatca cgcgcgacaa
    30481 ttgtacgatg tgcctgtaca tactgaagtc gttcctgtaa ttcaagcaat tctttgacgg
    30541 ttggaaaact agaaattaca tcgatttcct gattagtcag cggcttggta gataaaatat
    30601 aatcatactg actgagatca atactgtggt aatctactag agactgaata tctatcaact
    30661 ctacaaaagg agcaacactc ttaattttac tgactaataa atctctagtg acccgacgtt
    30721 catccgttaa aagcaaaaca cggactggat aaatctctgg actacggcct aagctagaga
    30781 taaaatgtag ggcaatcatg ccatactcat actctgtatg aagatatttc ggaaaaatat
    30841 cattcactaa aagactgatg actgtataaa gaaatttatt cctttcaact aaaatctgga
    30901 cagattctgg caaattttca ccctgaaaaa ggatagggac gcctaaactg agccgaatat
    30961 gatggaaaag aaaattgaat aaaaccttgt ccttaaaaaa gtcaatcttg gtatacatgg
    31021 aaaccgtatc aatcagattt gaaatattgt agaaaaattc accatcaaat ttctccgtaa
    31081 agagcggatt gtcctgacgt ttaatgatta attcatccaa gatgctcgca aaatagataa
    31141 tttcctgaat actataaaat tgtgcagtct gcttagagta agcttgaaaa attttttgag
    31201 aaatttccaa agcctgctta ctagtattag gtgaattttc aatgttttgc tcctgaccta
    31261 taagagataa caagatcgca aaaaacatct tcatcctagc atccatatct ggaaaacctg
    31321 acagttgctt attaacaatc tgactggcca gcctagttct atctgcttct aaaatatcaa
    31381 agctcccaaa attaccggtt gaaaaatctg ctactgagat acagtttgtc agtaaaatag
    31441 ccaaaaatct tctcttacca actgaatcac cagaaatccg ataacctttt tgtcgttcaa
    31501 ttttcagatc aaagtctaaa agacgcttat caatatctga aatatcctga ataatagtta
    31561 cattactgac tttcgtgcac tcttgcaatg cttcattggt gacaaaacca ctctcagtca
    31621 gaaggcgata ggtaatcaac tcttgtcttt cttggggact atactcaact aacacttcaa
    31681 gttctgtcgg caaatcatcc aactctccag tcaaaatata gtatttccca tgcttcgtta
    31741 tttcgattcc atattgctcc atgctatctg tcaaatctga taaagttcga taaattgttc
    31801 tagatgaaac ctgtaagatt tcagtcatat cttgcattga aagcttccct acatgtagga
    31861 aagccttcaa taattgttct tctcgtttgg ttaatagcat tcgtaattta gaaacctcta
    31921 gttctatttg tacattctag cagccatttt gtcatattct ggtgttgtta ctaaactatc
    31981 cacaataaga aattgagaat tcggtgctgc ttgctgcact tctgcctgta aagaaatagt
    32041 tgttacaatc attatgtttt tagaattaaa ttcacctaat tctgaaattt tggcagtaga
    32101 aactggaata cgaatattct tgtttctaaa gatagcccga atcgtttcac agcccatagt
    32161 tgcagttccc tgtgctttac cataagcaac tactacagca tcaatatggt taaggtcaat
    32221 ttcctgacta tctactggtg ctgaagttgg tatatctcct tcaatttctg ctattggaaa
    32281 agctcctgtt aatgaagcta caatttcatc ataacgaggg gacgctaaga aattatcaac
    32341 agaaacatga atagcacttg gactcttgtc tttagctctt ggtgtcagtt cttcctgagt
    32401 aacaattaat gtttttggtg tatcaagcaa atttgagatt gcctgattag atactggaat
    32461 ctctagacct gcttttttaa ccttatctcg aagaatacta gctcccatag cagagcttcc
    32521 cataccagca tcgcaggcga aaatgatttt ttccactgag tctgtcgaaa taactgcatc
    32581 aacagaagtt gatactaact gacctttaga ctgagcttta gctgcttggg tagcctcttg
    32641 agcagcttcg agcgaatcct cagttgactt gtctgcatga agaataaggg ctgctacaaa
    32701 gaaagaaaca actgctgcca ctaaaacacc tagaagaaca tttagatggg gccaaacacc
    32761 ttttggcgcc gtagccataa tcgcaataat agaacctggt gaagctggag atttaagacc
    32821 agcgtctaag agttgaaaag taaaagttcc agagatacct cctgccatag cagctaaaaa
    32881 tagagtaggc ttcatcataa cataaggaaa gtaaatttca tgaatccctc cgaagaaatg
    32941 aataaccatt gccccccaag aagaagattt agcagaacct ttaccgaata cagcataagc
    33001 taatagaatt cccaggcctg gtccaggatt agcttccaat aggaagagaa ttgacttacc
    33061 agcttgagct acctgttcta ctcccagagg agtaaaaatg ccatgattga gggcattatt
    33121 gaggaaaagg actttagccg gttcgatgat aatattagct ataggaagga ggcgagcatt
    33181 gacaatagcc tcaacaccat tcccaacagc tccagtaaga gtcgatacga ctggaccgat
    33241 tgcgtagaaa gccaaaagca ataatgcaaa accaacgaga ccagctgaga agttattaac
    33301 taacatttca aatccgggac gaattttttc ctggaacttc tcatcaaatt tcttgatagt
    33361 ccatcctccc agtgggccca ttaccatagc tccgataaac ataggaacac tagaacctgt
    33421 gattgcacca acagtagcaa tagctcctac aacggcacca cgttggccat ggatcatata
    33481 tccacctgtg taaccaatca ggattggcaa taaatacgtt aacataggac caacaacagt
    33541 agctaactgt tcatttggca gatagccatc agcgataaag agggcagtca atactcccca
    33601 agcaataaat gctccaatat tgggcataac catatttgaa agcgatgtcc ctagtttttg
    33661 aaccctgact ttcaatgata ctttttcttc cattagatca tcctcctttt cttaaaacta
    33721 gtatatacaa agttaaaaac ctttaaaact aaagttttgt cacaaatttt gtgtcaaaac
    33781 attacttttg acgaggctgg gcaaaaaggc ttaaaaatga taaaacgcat catatccggt
    33841 gtacatgaac tacaccccaa aagttagaca gaaaaaatct aactttttgg ggtgttttta
    33901 ttatgaaatt aacttatgat gataaagttc agatctatga acttagaaaa caaggatata
    33961 tcttagagaa gctttcaaat aaatttggga taaataattc taatcttagg tacatgatta
    34021 aattgattga tcgttacgga atagagttcg tcaaaaaagg aaaaaatcgt tactattctc
    34081 ctgatttaaa acaagaaatg attcataaag tctgacatga
//
LOCUS       DAYYYC010000022        31999 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.022, whole genome shotgun sequence.
ACCESSION   DAYYYC010000022 DAYYYC010000000
VERSION     DAYYYC010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.022"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..92
                     /locus_tag="ACHBV5_001071"
     CDS             <1..92
                     /locus_tag="ACHBV5_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFM9966883.1"
                     /translation="DYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(220..1242)
                     /gene="cbpF"
                     /locus_tag="ACHBV5_001072"
                     /pseudo
     CDS             complement(220..1242)
                     /gene="cbpF"
                     /locus_tag="ACHBV5_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
     gene            complement(1261..2082)
                     /gene="cbpG"
                     /locus_tag="ACHBV5_001073"
     CDS             complement(1261..2082)
                     /gene="cbpG"
                     /locus_tag="ACHBV5_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HFM9966884.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(2163..2402)
                     /locus_tag="ACHBV5_001074"
     CDS             complement(2163..2402)
                     /locus_tag="ACHBV5_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966885.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(2552..3321)
                     /locus_tag="ACHBV5_001075"
                     /pseudo
     CDS             complement(2552..3321)
                     /locus_tag="ACHBV5_001075"
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3322..3954)
                     /locus_tag="ACHBV5_001076"
     CDS             complement(3322..3954)
                     /locus_tag="ACHBV5_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFM9966886.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(3968..4963)
                     /locus_tag="ACHBV5_001077"
     CDS             complement(3968..4963)
                     /locus_tag="ACHBV5_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFM9966887.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDQDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(4960..5658)
                     /gene="liaF"
                     /locus_tag="ACHBV5_001078"
     CDS             complement(4960..5658)
                     /gene="liaF"
                     /locus_tag="ACHBV5_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFM9966888.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(5736..6746)
                     /gene="fni"
                     /locus_tag="ACHBV5_001079"
     CDS             complement(5736..6746)
                     /gene="fni"
                     /locus_tag="ACHBV5_001079"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFM9966889.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(6730..7737)
                     /locus_tag="ACHBV5_001080"
     CDS             complement(6730..7737)
                     /locus_tag="ACHBV5_001080"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFM9966890.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAESTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(7724..8677)
                     /gene="mvaD"
                     /locus_tag="ACHBV5_001081"
     CDS             complement(7724..8677)
                     /gene="mvaD"
                     /locus_tag="ACHBV5_001081"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFM9966891.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            complement(8659..9537)
                     /gene="mvk"
                     /locus_tag="ACHBV5_001082"
     CDS             complement(8659..9537)
                     /gene="mvk"
                     /locus_tag="ACHBV5_001082"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFM9966892.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(9659..9990)
                     /locus_tag="ACHBV5_001083"
                     /pseudo
     CDS             complement(9659..9990)
                     /locus_tag="ACHBV5_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771082.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            10653..10991
                     /locus_tag="ACHBV5_001084"
     CDS             10653..10991
                     /locus_tag="ACHBV5_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HFM9966893.1"
                     /translation="MTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANV
                     TAKKLIENYDTLEEIDFALGKSGVLLSLIKYYQFTNDNTLKTFIHNSIWGNLSLFPTK
                     RYSQRKHFRL"
     gene            10891..11361
                     /locus_tag="ACHBV5_001085"
     CDS             10891..11361
                     /locus_tag="ACHBV5_001085"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HFM9966894.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            11520..12752
                     /locus_tag="ACHBV5_001086"
     CDS             11520..12752
                     /locus_tag="ACHBV5_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFM9966895.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEIVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTLFLVLSPFSLI
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(12870..13868)
                     /gene="cbpJ"
                     /locus_tag="ACHBV5_001087"
     CDS             complement(12870..13868)
                     /gene="cbpJ"
                     /locus_tag="ACHBV5_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HFM9966896.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKELEIKTQDSVGRKYGEKRENSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYIGGERRAGWINDASAWYYLDPATGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(13887..14849)
                     /gene="cbpC"
                     /locus_tag="ACHBV5_001088"
     CDS             complement(13887..14849)
                     /gene="cbpC"
                     /locus_tag="ACHBV5_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HFM9966897.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLRSSGAMA
                     TGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLDPSN
                     GDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(14947..15636)
                     /locus_tag="ACHBV5_001089"
     CDS             complement(14947..15636)
                     /locus_tag="ACHBV5_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFM9966898.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(15648..17072)
                     /gene="gndA"
                     /locus_tag="ACHBV5_001090"
     CDS             complement(15648..17072)
                     /gene="gndA"
                     /locus_tag="ACHBV5_001090"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFM9966899.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(17148..18542)
                     /gene="mapZ"
                     /locus_tag="ACHBV5_001091"
     CDS             complement(17148..18542)
                     /gene="mapZ"
                     /locus_tag="ACHBV5_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HFM9966900.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(18555..19712)
                     /locus_tag="ACHBV5_001092"
     CDS             complement(18555..19712)
                     /locus_tag="ACHBV5_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFM9966901.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARLPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFDEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(19797..20177)
                     /gene="rnpB"
                     /locus_tag="ACHBV5_001093"
     ncRNA           complement(19797..20177)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACHBV5_001093"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(20198..20527)
                     /gene="gpsB"
                     /locus_tag="ACHBV5_001094"
     CDS             complement(20198..20527)
                     /gene="gpsB"
                     /locus_tag="ACHBV5_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFM9966902.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(20597..21124)
                     /locus_tag="ACHBV5_001095"
     CDS             complement(20597..21124)
                     /locus_tag="ACHBV5_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFM9966903.1"
                     /translation="MATALVLGYSTFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            21190..21786
                     /gene="recU"
                     /locus_tag="ACHBV5_001096"
     CDS             21190..21786
                     /gene="recU"
                     /locus_tag="ACHBV5_001096"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFM9966904.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            21783..23942
                     /gene="pbp1a"
                     /locus_tag="ACHBV5_001097"
     CDS             21783..23942
                     /gene="pbp1a"
                     /locus_tag="ACHBV5_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HFM9966905.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(24109..29427)
                     /locus_tag="ACHBV5_001098"
     CDS             complement(24109..29427)
                     /locus_tag="ACHBV5_001098"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HFM9966906.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQ
                     NDNAGKPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYD
                     KDGWFWEYKTPGNSTWYKGNRVAAPETGSINRLSITLKSDGQLNASNNDVNLFDTVTL
                     PAAVNDHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKV
                     TYDTIQSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKIN
                     ETTAEYLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLL
                     SSISFLGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVS
                     TDKLAAGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFP
                     EYTKELPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFG
                     SQAQNPFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDF
                     KTLIEKAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDA
                     AYDLAHGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRF
                     AIEWGHGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAA
                     NYPLLGGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDN
                     GSTYKWTPEMRVELVDANNNKVVVTRKSNDVNSPQYRKRTVTLNGRVIQDGSAYLTPW
                     NWDANGKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVK
                     DGKITLDLLANQPYVFYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEI
                     VKSQGANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKE
                     VTTYTNKSLALNYVKAYAHNTRRDNATVDNTSYFQNMYAFFTTGSDVSNVTLTLSREA
                     GDQATYFDEIRTFENNSSMYGENHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRT
                     HLSEKHDPYTQRGWNGKKVDDVIDGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYR
                     VTFEYEAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTG
                     AETGDTWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALK
                     NYLPTVAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTA
                     LVADDFASLTAPAQAQEGLANAFDGNVSSLWHTSWGGGDVGKPATMVLKEPTEITGLR
                     YVPRGSGSNGNLRDVKLVVTDESGKEHTFTATDWPNNNKPKDIDFGKTIKAKKIVLTG
                     TKTYGDGGDKYQSAAELIFTRPQVAETPLDLSGYEAALVKAQKLTDKDNQEEVASVQA
                     SMKYATDNHLLTERMMEYFADYLNQLKDSATKPDAPTVEKPEFKLRSLASEQGKTPDY
                     KQEIARPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(29727..31709)
                     /locus_tag="ACHBV5_001099"
     CDS             complement(29727..31709)
                     /locus_tag="ACHBV5_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM9966907.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDGYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVMAPVNEEFLNSKGDDFAKATDPNSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
BASE COUNT         9172 a         7260 c         5688 g         9879 t
ORIGIN      
        1 tagactatat tgattattac aacaacaaga gaattaaggt aaaactaaaa ggacttagtc
       61 ctgtgcagta cagaactaaa tcctttggat aaattatttg tctaactttt ggggggcagt
      121 acagaaaaac cttgatacta tgcgtttttt gattgtgaag acttttatcc acctattata
      181 caaagttaag tatccatcac agtttacaat tagccttcat tacttaaccc attcaccatt
      241 atagtttaag tagtaaccac ctactgtggt attaacagct aaagcacctg aatcataggc
      301 atagtaccag ttaccattga cttggaacca gcctgttttc atatctccat tacttgcatt
      361 tagatagtac caagtcgaac cttcctgata ccaaccagtt gccatagctc ctgatgaacg
      421 gagatagtac cacttgttac caaggtattg ccagccagtt ctcatatcac cattttcagc
      481 atctagatag taccaagttg agccttcctt ataccagcca gttgccatag ctcctgacga
      541 atggaggtag taccatctat tacctagaaa ttgccaacca gtttgcataa tgccagttgt
      601 tggatctaga tagtaccatg gagctgcttt tagcttctct tcatcatagg taagagggga
      661 atccttaacc caaccacgtg ctagctctcc aaccgccaat ctgttgatgc gcgaatcaaa
      721 gccaccatcc ttctgtaaat aataccaatg accctcttcg taaatccaac cagtttttaa
      781 agtatgataa ctacgctgat cttcaaaata atagactcat ttctctgctg ggctatcata
      841 ttcttcccca tgatgtttgt tggtattcgt agcagttttt gcttctaaaa cttgcttgcc
      901 aacaaattct tgtaatacac catcttgacc aaaataaaac caatctggtc taagagaaat
      961 ctctattctt ggagaaggac caatcgtaac ccccttgtgt ggagcaggta tatattgcca
     1021 gccgacaacc atctctccgg ataaaggatc aaaataatag tacttcccat ctatcactct
     1081 ccagtaggtt tcttttagat cccccttttt gtagtaggtt ctaccatttt cttggacaaa
     1141 ctgccatcct tcagaatcat ctgcaaatac tgtactggtc cctagcaaac cgaagaaaaa
     1201 tgtggctagt gcgacttgca tcattttttt caaaagcttc attttatata tcctccaaca
     1261 ttaaatccac tcaccagatg aagcgaagtt ataaacttta ccatcgatag tttggctacc
     1321 tgtaaccatt gctccatttg aattgagata ataccatttt ccatttactt tttgccaatc
     1381 tgtaagcatc ttaccggaac tgtctaaata ataccaagta tcatttatct cctgccaacc
     1441 cgtttgttta tcatgttgtc tataatggta ccaactacca tttattttct tccatccttc
     1501 aagagagtaa cctttaagaa ccgaataaat aaatggcaaa tttcgttcat ttaatttaac
     1561 tgcactgtta atttgattag ctccatctcc taaagtatgc actcctacta cacggtgact
     1621 agcatcataa actgtagatc cactagaccc ctctaaagta tcaacttggt aatccaagaa
     1681 catgccatca tcacttaaaa cttgtttttt atctgtatac atttgatgaa ttttaaaatt
     1741 atatgatgga tagcctgtga tagtcacagt tattcctgtc aaattttttt gactagtagg
     1801 aagacccaaa gtccctaatt ttgcaccaat gggctcttct agaattaata aagccaagtc
     1861 atattccctt gcatccttag aatttaaatt tctaaattcc ttcaaataac gaacttcctt
     1921 tactttgatc tttccaaata gttcttgact tggactaaca gccggaagaa cataaatatc
     1981 atccgcttct ttcccatagt catgtctgta gtagttgtga gccgctgtaa ttaacacatt
     2041 atctttaata aaattcgcac ttcccctccc ttctacattc attccatcgg ctactccata
     2101 atacttagat aaaaccatag ctgaagtcga atacggatac tgtaaagtat tatcaatttt
     2161 aatcaaatca tcattaccga taatacttct gattgctttt ggtagtatga accatacgtt
     2221 ggtgaaatct cagataatga agaatcatta gatcctggac ctttttctag tgtctcactt
     2281 acctcatatt cttcacccgt actagaaata acactcaaag cagatactgt cgataactgg
     2341 ctagccaata aagtactcgc aataattgaa atacccaatt ttttataaac agttttcttc
     2401 attattgtag cctcctaatg taattatagc ctactattct aaatttctta atctactata
     2461 gaatcaagaa atctaccacc ttctttaaat accctccatt atcacataaa caggtaaact
     2521 tttcaattaa tgactgcgct tttcaatcac gctagaggta cttgcttgct tctttgatac
     2581 taagttcagc cattctttcc ttgttttcat caataaagca tgttacccaa gttggattcg
     2641 ttttggagta gtttcgcaga atccagccaa tggctttatt gataaaaaat tctgtttggt
     2701 tcaagttatg aagtagaatc ttttccatta attgagtatt ggtcttctct tttcttaaca
     2761 actggtggtc aatagcgaca cgtctcagcc agatattatc tgataggctc cattttatac
     2821 tcaatgaaaa tcaaagagca aactaggaag ttagccgcag attgctcaaa acactgtttt
     2881 gaggttgcag atagagctga cgtggtttga agagattttc gaagagtatt aagattattt
     2941 cttctagttc agggtgttca tacaccaaac tccctactac tcgatctagg atatctaccg
     3001 tgtcccacca ggattttgtc acgactaact gctctagctt aggcaaatcg gtttccttta
     3061 gataagactg cattgctttc aaatagttag cagccacata ttggtatttt ctaggctcct
     3121 tttcccagca agtgtctgca aaatcccaat cgataatctt tgtttttttc gcttctggaa
     3181 aatattttta tagagtttat ttctttcagg caccgcaata cctagaaaag aaaattgatg
     3241 gcgcatatag gcttccatgg accttgcttt tttagagtct tttgctgctt ctagctcctc
     3301 aagtaaatct gctaaactca tctaaaactc ctcttgcccc accaaatggt gctgaaaggc
     3361 atagacagcc gcctgggtac gatcgctgac ttcaagtttg gcaagaatat tggacacgtg
     3421 ggtcttgacc gtcttgagag agataaagag gtcatctgcg atgcgctgat tttcgtagcc
     3481 cttggcgatg agttggagaa catctcgctc acgcgcagtc aattcttcat gaagttccat
     3541 atgattgcgg tggtattcaa ccttcttgct aacctcttgc tcaatggcca gctcgccagc
     3601 agctacctta ctgacggcat gaagcaattc atctgcacta gaagtcttga gcatatagcc
     3661 tttggcacca gcatctaaga ctggcatgat tttttcattg tccaaataag aggtcacaat
     3721 caaaatcttg gcttcaggcc attctttaag gattgctaag gtcgcgtcaa tcccattcat
     3781 ctcaggcatg acaatatcca tgacaatgac atctggacgc agttccaagg ccaagtcaat
     3841 cccttgagac ccgttggacg cctcacccac aacttctaca tcgtcttgga ggtcaaagta
     3901 gcttttcaaa cccaaacgga ccatttcatg gtcatctact agtaaaattt tcatctttac
     3961 tcctttatca ttccttatct aacaggggaa tacggatatc aactgccagc ccttgcttgg
     4021 gagctgttaa taactgaacc gtccctgcca tatcttcaac ccgctccttg atatttcgca
     4081 gtccataact caagtcgtct aagctcccta actggaaacc aatcccattg tccaccacct
     4141 tcagttgcaa ttcaacatct gtctgataga ggtagacatc taggcaagat gcctgggcat
     4201 ggcggagggt attgctaatc aactcttgca ggatacggaa gatatgctcc tcgattttct
     4261 taggcaattt cgtcatattc tgcttgagac taaccctaag atcactcttg tcctcaagct
     4321 cttttaagag aatttgaatc ccttctatca agctcttctg ctccagttca actggtcgca
     4381 aatgcaagag caaaacccgc aaatccttct gggctgtttc taaaatagct gtgacactct
     4441 gcaactgggt ctgcatcttt tctctatcca atttcaaagc ctgctgactg atacccgata
     4501 aaatcatgtg ggccgcaaac aactcctgac tgactgtatc gtgcaaatcc cgagcaattc
     4561 gcttccgttc cttctcgatg atttcctctt cctgagcaag gctatgattt tcagcttttt
     4621 gaagagcctc tgtcaaaagg ttaagtttac ctgataagga cttgaaactg gcatccaaat
     4681 cttgatctac aacctgaact acttcttgcc ctgccaataa acgcttgaga ttagcctgca
     4741 tttttcttag agaaagctct tcgatccctc gccaaaacag ggctaagaga caggtcatgg
     4801 acatgctgaa aaccaacaat aaaaagacaa atttttctgt tttttcgaca tcgtgcaaaa
     4861 agatagacca gtcaaaatca agtatttcca gcaagctgtg ggagaaaaaa aagacaaata
     4921 ggaaggaggt gagagcaata atgacatagg cttgtttttt catcctctaa ccacctccac
     4981 atcaccaatc atagtggtca agaaaatctt gacactcttg ttactcttga gatagtcttt
     5041 tgtttcttga tgatagtgtt cattgcggag ggctcgcttg ggctggttga aaaaagtcaa
     5101 atccccatag agacagttaa cgctgagact gacttccaca tctacaggta cgatgatttt
     5161 ggtcgttcct accatctttc tgaggataat gacattgtca tgattggtta agatgaccct
     5221 ctccagatga atagtgtcct tacccatgaa gcgaaagaga ttgatatcat cgaattggca
     5281 agtctggtag cttgaaaaat gatgaagatt tccaaaccaa cgatttttct ccttcttaac
     5341 cgtcacgacc tcttcaaaaa ccaaattggt ctgctctttt tcctggttca tcatcgggta
     5401 aagaagaaag aggctataga taaccgcaac aaaaatagct agaatcacaa aaggattgag
     5461 cataacgatg aaaaagaaga gaatggttgc cgctactaaa agaagattat ttccctcttt
     5521 accagtgtag tagcgaatca aaagcaaaaa gaggaatagt atcagcagaa aacgcgaaaa
     5581 atgctctgat accatcaaaa tcagagctcc tgtcagaaga caggcttcga taaataaaaa
     5641 gattttaaat tttctcatag gttcatcctc tcccttctat tttatcacaa ttcaaaaaag
     5701 tcacctcagt ctgaggatgg aaaaaaaggc gctggttacg cctttttcat ctgatccttt
     5761 gcttctttta attttccata aagaagatag tctacttttt gtagatctgc tatggtggca
     5821 cagttaaggg aacacataat caagcgtaga tctgctttcc agccttggac aatgccaatc
     5881 acttcttcaa ctgtgtaggt ttcaaccaat tccagaacgg ttcgtgacaa tcccacagcc
     5941 ttagcaccaa aaaccaagca cttaatcata tccagcggat tccgaacccc tccactaacc
     6001 aagagttcga ccttatcttt ccattcttgg gcattgagaa gggcctgcat ggtagactga
     6061 ccccattgat tgaggtaatc acgctggcca ctacgacggt tttcgatata ggcaaagctg
     6121 gtgccaccac gacccgatag gtccactgta cgaacaccga attcataggc tctttcgatt
     6181 gtcttggcat ccattccaaa gcccacttcc ttgaggacaa taggaacggg aatttgcttg
     6241 ctataatctg ctagatgcga ttgccagctt ctaaacttcc tttctccctc gggcatgagt
     6301 aattcctgca tgacattgac atgcacttgc aatagaacag gattcatctc ttctacagtc
     6361 tgaagtccta actcgacagg tttgtccaat ccaatattgg ttccaaggag gagattggga
     6421 tgactagact tgacagaaaa agaatcatcc gttggatttt tgagggctgc gctataagaa
     6481 cccgttacaa ataaaatacc acaggattcc gccacctgag ccagcttttg attgatttct
     6541 cttcccttat tacttccacc agtcatggca ttgatataaa aaggaaagtc ccactttcga
     6601 ccagcaaact ctgtcgaaag atcgatttca tccagattgt aaagaggcaa ggaagaatga
     6661 atcagctcca cctcatcaaa gctattatag gaacttttct gctcaagggc atagaggata
     6721 tgctcgtcct tacgatttgt cgtcatgtcc tatcctttct tgatataaga gctcaatccc
     6781 cagatcggcc caacgatttt ttaaggtttt ggttgattcc gcatcaaaac tcagggcgat
     6841 gccacagtca ccaccaccag caccactact cttggcaacg gcctgcaaat cttgactggc
     6901 ttctttcaac tgtctaagca aaggcgtgta aatatctgta ctcaagcctt ctaaaagctt
     6961 gctggctact tctacttgct cgataacttt ttcggctttc ccctgttcca aggcttcgac
     7021 caaagaaacc accgtttctt ttgaggaact taaaaaattt tgattgatat tttgcttgat
     7081 ttgctggacc atgtgactcg atacagccac ttccttggtc catcccacta agaaatcaca
     7141 ttctaaagtt ggtttcactt gtgaaattga aaagccccaa tcacgctcca gaactgtcgc
     7201 caagttttct tcttctaacc aagcagccac cttctggcga tcaaatgact ggtagagaac
     7261 caaatcctct gccacaatac aggcaaggtc gcccatggaa ccattgtctc ctcgcttaag
     7321 caagacagcg ctagtcagct tgaacaagag ctcctgatca acagaaacat catacagagc
     7381 cagtaaagcc ttgacaacca agacaacgac gctgccacta gaacctagac caaacttttt
     7441 cccttctcgt tccattttgc cacagatttc tagagaaaaa ggtcttaaat tctgaccacg
     7501 aacagcgagg aagtctccca tcaaagcaat cgtttcttga atcaagctat agtcaggatt
     7561 aggccttaag tccactgcga aatcaaacat atctgaatag atacggtagc tgtcagaaaa
     7621 agcaatctca gccctcatat agatgggaat atcctttatc aaagctaact gccctggctc
     7681 taaaatagca tattcacctg cccaatagag ttttccgcaa gttttaacag caatcatctt
     7741 gactcaaatc ctttgttttt gacacaatca agcgataacg atgaccgaaa atttctgata
     7801 aatgctccaa gtctttctcc tgacagaaga ccttaacatt gggaccagca tccatggtaa
     7861 agtagcaggc ctctcctttc tcacgaagct ggcgaacaaa gtccatagcc tcataagagg
     7921 catccgtcag ataagaaaag gctggactag cagtctttgt cgtagcatgc atagccaggg
     7981 catttttctc cgttaattct ccaatcttgg caaaatcatt ttccttgaga taaatcagca
     8041 tatcctgata gtccttctca gactgacgaa cccagtcgtc gaaagtcgtc gaggtttcca
     8101 cacaaagttt catcccgtca cggctagaga ttggtttttt cttgtcctct agcaccaaca
     8161 taatcatagc tagtttcaag tctgtctcta cagggtaaat ttctccacta tccttatccc
     8221 aggctcctag tggtccataa aaactccgag aagaagaacc tgaggcaaat ttggcttcct
     8281 gtgccaactg acttctatcc aatccaagct tgaaataagc attacaagcc ttgaccaggg
     8341 cggacaaacc actagaactt gaggacagac ccgctgccgt aggcatattg ttttgagtat
     8401 cgatacggac aaagccctca ccagctggac gataacggtc aataatctta ctcatcttgg
     8461 catgctcgac ctcattttgt agctgaccat tgatgtaaaa ttcgtcagct gttacattgg
     8521 ctggtaaagg cgacaaggtc gtctctgtat acatattttc caaagttaga gaaatactgc
     8581 tagtagcagg caccatctct ttttcttttt tctttcccca atatttgata atagcaatat
     8641 ttgcgtagga acgtactgtt acaggctctc tatccatgtc tgaacagctc ctttctcttc
     8701 taatctttct gctagttctt gtgcgtgtgt caaattggtt accaaggcta tgatacaacc
     8761 tcctagccca ccaccgctca tcttggcacc cagagcacca tggctaagag tcgtttcaac
     8821 caaaaagtct gcctcagggc tactgactcc aatttctttt aaatgtaaat gcgcttgact
     8881 gaggatttgt cccagtcctt cagcatcttt ttgtgaaatc gcaacttctg cttgctgggt
     8941 taattctccc aaggcatgca aaaacggtag ggcatccttg cccttatttt gaaccacttg
     9001 gatggcttca cgagtatgac cataaacacc cgtatcggca atcaccaaat aggcggataa
     9061 atccatctca agttctgtaa atcctacgtt cttgataaag cgaataggtt ggtcactaag
     9121 acaggtctta gcatccaaac cactaggatt catatgggca atcatttcag ctcgattgac
     9181 caagatttct agtacatcat gaggcagatc agcctgatag tagtcaaata ctgcacgaat
     9241 ggccgctatg ctgatagccg ctgacgaacc catcccccgt ttctcaggga tagccgagtc
     9301 aatctcacaa cgaatgcagg cttctgtgat attcaaatac tccagtgagg cataaaccgc
     9361 catggacaag gtatcctcct cataaaggcg ccaaggactc tctgcaggaa ctaccttaca
     9421 ggtcacctcc acctccaaaa gaggcaggga aatggcagga taaccgtaaa cgaccgcatg
     9481 ttcccctatt aaaattatct tactatgtgc ctgaccgaca ccaacttttt ttgtcatttt
     9541 ttccttttac tagacgaaaa aacgtcttat ttttcataca agtattaatt ctttcctatc
     9601 tattttatta tattttcaca aaaaaagcga ttgtttccat tcacaatcgc ttctttcatt
     9661 attgaaccca ttcgccatta tagttgacag aatagccatc tacggtcgta ttcactgcca
     9721 aggcacctga gcgctataag cgtagtacca tctgccattg acctggaacc aacctgtcgt
     9781 catagaacga cgaaagaaac tccataccat taagtaaaga ggaaagtcgt gagggagcat
     9841 gcgccattga caacctgttt tagtgacgta caaagtctca ttaacaagta ctcgtttcgg
     9901 ccatttatag gtgcggtgtt tggagaaata gggttcaatc ttcgcccatt cttgatcgtt
     9961 taaatcagta tcatatgctt tgcgtatcat aactctagct taacattttt ttgtgaatac
    10021 aggttctaaa taatcgacca cgaaaatttc ttaagtggaa aacgccttat gaagtatgct
    10081 acgggaaact tatgcactta atttgacaat tcaagatgta aaaatatata ctatagtaga
    10141 ttgaaactag aatagtacac ctctacttct aaaacatttt tagaaatcga tttgactgtc
    10201 ctgatcgatt tgtcctgtta ttatttcatt ttactataat atttgataag ttatcctaaa
    10261 agtgttatta tgttgttgtg ttatagattg attgaatcta cctaaaggat cctattcaat
    10321 tactagaact atcacatact caaggtcagc tcacagatga gcaactattt tggttacaat
    10381 gtctactaaa tttaagtcaa acaaataatt tagtcaaaat taaaaaaata gaggaacata
    10441 aatatgatta caaaacagaa tgtaatagtg ttctacaatt tttactagat aaaactgtaa
    10501 attctgaagg aaggatcact tcttcaacag aatttagaaa tttcgtaagt aatttatcat
    10561 tccaacacgg aatagctgga ctactgtttc ctctaaataa attgtacccc ccagaactgg
    10621 attctaaaat actctctatc atcaagaagg cagtgacaat tagaacgaca catacatatg
    10681 aatatcaata ctcactgcta tttggtgatg caggctatct atggttactc ctacatttat
    10741 tttctatcag taaaaatcaa tactatctac aattagcaaa cgtcaccgct aagaaattaa
    10801 tagagaatta tgatactcta gaggaaatag actttgcatt gggaaaatct ggtgtcctat
    10861 tatcattaat aaaatactat caatttacca atgacaatac tcttaaaact ttcatccaca
    10921 atagtatatg gggaaattta tcattatttc ctacaaagag atacagccaa agaaagcatt
    10981 ttagactata gctttgctca tggatattgt ggaattgcat atgctttatt tgcctattct
    11041 aaagtcttag aaccttctat gttctataat gatctccata cattccatgc tgaattaaaa
    11101 aaattattag aaaaagttac ttctaatact gaaaatttag gaaatttaca actttcttgg
    11161 tgcgaaggaa tttccggaat aatcttatat ctttgtatgt acgattgtga cggaaacaaa
    11221 gatattatta gtaaatatca agaatttgtt tttaaccatc atctaaaaat gatgacagga
    11281 tattgccacg gaataactag cttactacaa accactgtct acaatcaaaa caaattactg
    11341 atgaaaaaat ccaacaggta attttagcat gttctgaacg agatgatcac ggtttactga
    11401 tgtttcaagg agatagtggt aaagcagatt tgtttgactt cggaatagga agcagggggt
    11461 atattggtgt ctattaaata ataaattccc attcgatgtg cagacataag gagaaaagta
    11521 tgaaattatt ttggacaaac aacatatata gacagttgct gctaaacagc tgtttttcat
    11581 cattcggcga cagtattttc tacctcgcca ttatcaatta tgtggctcag tacaatttcg
    11641 ctccgctagc gattttactg atttccattt cagagatagt tcccctacta tcgcaactct
    11701 ttctcgggat tctaggagat tttcaagaaa atagagtcaa acacgcactc tgtattgcca
    11761 aaatcaaaat cctgctctac gctattttga cactatttct cgtcttgtcg cccttttcat
    11821 taatttcagt cattatgatt gtcatcatca acctcatctc tgacaccttg agctacctgt
    11881 ctgcctacat gatgaacgcc ctctacatca gtgtaattaa ggacgacctg catgatgcca
    11941 tggggttcag gcagtctctg atgagggttg tccgcattgt cgccaatcta gctggcgcat
    12001 tccttatcaa tgttatgagt attcaaacta tttcccttat caacactctg acttttgtca
    12061 ttgccttttt gggcctgtat gttattcgac ataccttgta tgaggttgaa aaaaggattg
    12121 aaatgtcaca tacagcactg agttttaaga aatattttca acatcttaaa cagtcgctgg
    12181 ctgtgctcct gaggttaaaa gataccgtca tactactgtt tctgacgacc agtatgattg
    12241 ccatcttgga tgtgtcccct cggctgattg ccctccgctt catccaacag acactagcac
    12301 aactgagcat tgggcaactc ttcgccctgc tctccatcat catgtcttgt ggagctatcc
    12361 ttggcaatat gaccagcagt aatctattta aaaatatccg tttcacgcac ctcttggttt
    12421 tctgtgagat ttccctattg gctctaataa ctagtatcct ttgtcaagcc tatatcgtaa
    12481 ttttcgtgac cagtttcatc agttctacga ttatcggcat tctcagccct cgcctacaag
    12541 cagctgtctt tgcccatatc cccagtgaca agatggggac ggtgggctct gctctgagca
    12601 cagtagacat tctcgccccg tccctgctct ccctattagc cctatccata gcatcgggcg
    12661 tttcggtgca gttagcattg atatttttgt atcttatttt gattgctctt atcttttgtc
    12721 aatggttagt caagttcaac actcataact aacgaaaaag catgtgtaga tttcacatgc
    12781 ttttaatctc cccaatcgtc aggtcaagta caacaaagtc acttctttga ttaagcgagt
    12841 gttctaatat aattataagc gccctgtcat taccgaaccc attcgccatt atagttgaca
    12901 gaatagccat ctacggtcgt attcactgcc aaagcacctg agctataagc atagtaccag
    12961 ttgccattga cctggaacca acctgtcttc atgtctccat tacctgcatt taggtagtac
    13021 caagttgaac catcttgata ccaaccagtt gccatagctc ctgatgaacg gagatagtac
    13081 catttgttcc caaggttttg ccaacctgtt ttcatatcgc catttgggtg gtctaaataa
    13141 taccaagtgg taccttcctg ataccagcca gtggccattg ctcctgagga acggaggtag
    13201 taccacttat tacctagata ttgccaacct gtttgcataa taccagttgc tggatctagg
    13261 tagtaccaag ctgaagcatc atttatccaa cctgcacgtc tttcaccacc aatatagttt
    13321 tctccattaa tttctgtttt agctagataa taccagttag actgatcata aagccaacct
    13381 gtctctaaag aatgattttg attaaagtaa tagttcgtgt aataacgctt ctcttcttta
    13441 tcttctgaat tttcacgttt ttccccatac tttcttccaa cactgtcttg agttttaatc
    13501 tctaattctt tccaaccaac aaactcttgt agcactccat ttttatcaaa gtagtaccac
    13561 tctgactttg gaaaaccttc taatctgata ccatttgggt aaggaccaat tgtactacct
    13621 ttagatggaa acgggatata ttgccagccg acaaccatct ctccagatag agaatcaaaa
    13681 taatagtact taccatcaat cactcgccag taggtttctt tgaggtcccc ctttttgtaa
    13741 taggttctac cgttttcttg gacaaactgc catccttcag agttatctgc aaatactgta
    13801 ttcgtagcta gcaaaccaaa gaaaattact gttagtccag cttgcatagt ttttttcaaa
    13861 agcttcattt tatatatcct ccaacattaa atccactcac cagatgaagc gaagttataa
    13921 actttaccat cgatagtttg actacctgta accattgctc catttgaatt gagataatac
    13981 cattttccat ttacttttgt ccaacctatt ttcatatctc cattagaagg atctaaatag
    14041 taccaagttg aaccatcttg ataccaacca gttgccatag ctcctgagga acggagatag
    14101 taccatttgt tcccaaggtt ttgccaacct gttttcatat cgccatttgg ctggtctaaa
    14161 taataccaag tggtaccttc ctgataccag ccagtggcca ttgctcctga ggaacggagg
    14221 tagtaccatg gagcaggttt gcttctatca atgtcaatag taacatgaaa atcttgagtc
    14281 caacccttag caacttcacc aattggtagt ggattgtaag aatcatcacc aaaatttcct
    14341 agcttattta aataatacca attgccgtct tcataaatcc agcctgtctt tacagcataa
    14401 ttattatcaa aataataagt tctcttttca gcagatagag gatattgttc accgtatact
    14461 tttcctgtat tttcagacgt ttttgcctct agtacttgtt tatctgtttg ttctagcaaa
    14521 gcaccatctt gtccaaaata gtaccacttc tcctgaaggc caatttcgaa gactggacga
    14581 ttatcaaata aatcatcacg ataacctgtt ccaggaattt ctaagtattg ccaaccgaca
    14641 accatctctc caatatcacc aaaatagtaa gttttaccgt ctattttatg ccaatagatt
    14701 gctttatgat catcttttac ataatatttt ctattatcct tatcaacaaa tcggccacct
    14761 gtggtattcg caaataccgt atttgtagct agcaaaccaa agaaaaagac tgctagtaga
    14821 acttgcatca tttttttcaa aagtttcatt tatatatcct cctaaaacga ttgtagcaaa
    14881 gacacgactg catgtcaata tataaaaact cctcaaaaaa gcagttacac aactgcaact
    14941 gcttttctat tcttgcatgg tgtaaccaac accacgcacg gttttaatgt agcttttttg
    15001 tcctttaaca tcaagcttgc tccgtagata gcggatatag acatctacga tatttgtctc
    15061 ggtcgcactt tcatacttcc aaacactttc caacaattgc tcacgagtca atactttctt
    15121 gcttcccata agtgtcgcca aaaggtcata ctcacggcgg gtcagagcaa tcatctcttc
    15181 accacgataa accgtgtgat gttcaacatc tatcctaaga ttgcggtagg tccttggaac
    15241 tttcatcaga ctgcagtgtt gatcaatgaa gtcccgacct cggaagatcg ccgaaatacg
    15301 cgctaccaga ttttcgataa agactggctt atagatgtat gaaactgcaa aacgctgaac
    15361 aacttccagc tcttcttgca agtcttccca atgatctaaa atcatgatga ctgaggcagg
    15421 tttagttcga ctcaattttt ctgcaaaatc ctgagccatc atatctccca gattaacgtt
    15481 caataaaatc aaatcatagt ctgtctgaag agccatggaa agggcttttt gcccctcctc
    15541 taccagatca acccgatact gctctttctg gagttccaaa cttaaaaaat gagctagatt
    15601 tcgttctttc tcaagtaata aaatccgttt ccccatggct gacctactta tttttcgtca
    15661 taccaagagt agtggaaggt tccttctttg tctttacgtt ggtaagtgtg agcaccaaag
    15721 tagtcacgtt gtgcttggat caagttagcc ggaaggtcag ctgaacggta gctatcaaag
    15781 taagtaatag ctgctgagaa agttggcact ggcacaccag cttgaaccgc aagagctacg
    15841 atatcacgca ctgcttgttg atacttagca gtaacatcca agaagtactc gtccaaaaga
    15901 aggttggcaa gatctgcatc gcggttgtaa gcatctgtaa tcttttgcaa gaaacgagaa
    15961 cggatgatac agccatcacg ccagatagat gcgatatctg caaatggcaa gttccagttg
    16021 ttttctttag aggctacacg caattgagca aatccttgtg cgtatgaaat gatttttgag
    16081 aagtaaaggg cttgacggat tttttcaatc aattcagcct tgtctccttc aaagttgaag
    16141 gcagctggtt ttggaagcac cttgctagca tgtacacgtt cttctttgta agttgaaatg
    16201 tagcgtgcaa acactgactc agtaatcagt gacaatggta caccaaggtc aagagatgat
    16261 tggctcgtcc atttaccagt tcccttgtta cctgcagcat caaggatgta gtctacgatt
    16321 ggtccatctt ggtcttcatc gtctttacgg ctcaagatat cagctgtgat ttcgatcaag
    16381 tagctatcca attcaccctt gttccactca gtaaagattt cagccatatc ctctgcagaa
    16441 aggcctagca agtgttgcat caagtcatag ctttctgcga tcaattgcat atcaccgtac
    16501 tcgataccgt tgtgaaccat tttcacatag tgaccagctc catcaggacc gatataagtc
    16561 acacatggtt tgccatcttc tggtgcttta gctgagattt cttcaagaac atccgaaacc
    16621 aattcgtagg cctctttttg tccaccaggc atgatagaag gaccttcaag ggcacctttt
    16681 tcaccaccag aaactccagt accgataaag ttgatacctg agtttgccaa ttcttcatta
    16741 cgacggatgg tatctttgta gaaagtgttt cctccgtcaa tcaagatatc acctttgtca
    16801 aggtgtggaa gaagggcttg gatagtagca tctgtaccag gtccagcttg aaccatcagc
    16861 atgatacgac gaggtttttc gattgagttt acaaaacttt caacgtcata gcttggtaca
    16921 aaattctttt caggatggca agcaatcaca tcttccgttt tttctttact acggttgtag
    16981 atagcaactg tgtaaccacg tgattcaata ttaagggcaa ggttacgacc cattacggcc
    17041 atacctacga caccaaagtt agcttttgtc atttgacact cctcttgttt catttgtttt
    17101 attttatcat ttttactttt gaaaagaaag aattttgtaa cgactgctta gtagtccaag
    17161 tcatccgcat gaccagcgcc atttccgaca aagtagcctg tcttacagtt aagggtaaag
    17221 agataggttc catctggctt atagaggttg taataaccat tgccgttaac gatattgaca
    17281 cgttcaagga tatattggtc tccagtgata tagccacgtg aacgtgaagt tgctagaatt
    17341 tgttccaaaa caccatccgc aaaatcccag gcagagttat tactatcatc aatagcagac
    17401 tgattatagg caacacgact ggcacttctt tgaacagcaa cccctgcact cgagagaccc
    17461 atattgactt cactgcgact acttctagtc tcatttgaac tacttggttt tggctcacta
    17521 gtcgtatttg aacttgcttg acttgaactt gagctgctag tttgacttga acttgagcta
    17581 gaagtacttg tttgctggct cttaccaaga ctgatagcct tatctagcac tttatcaagc
    17641 tccgtatttc cagttttaat atccgtaaat ttagcatccg atttggcttt ggcattggta
    17701 tccaacacac catccacaat agctggtttt tcaaattgtg cattgacatc ttgaatggcc
    17761 ttgatttgcg ttactagact atcatattta gatttggcaa gcgtatgttc acgactacct
    17821 tccagcttat caagtaaagt cttgagttga ctcagtttat caaactggct atttttcaaa
    17881 gccgttttat tgctatttgt gtaaaaggcg tcataaagtg tattaaaatc atccacatcc
    17941 gattgattgg ctgtagttga ttgagaagtt tcaatttcct tggtcgaacg agccacttga
    18001 cgatagacat aataagcact gacacaaata attactgata caagcgccaa aacggtcaaa
    18061 ataaagcctt ttttactttt cttttctgag tcctcttgat ccagacgaga aaggttttgc
    18121 tcctcttcca cttcttcagt catttctgtt ggattttcat catctagcaa tagaggatcc
    18181 aagccttgct cctcatcgtc cagaggcaag ggtagtaaga tgtcttcaga agatggaact
    18241 tcctccgaag aagcttctga cttctctaca gcctcacgca tctcttgaat taaatcatcc
    18301 agactctgag tttcaacgaa ctcctctttt ttgtattgac gagtcgcaaa cttatccgcc
    18361 tcaatttcat ctctgtgttg cttaacatac ttgtccaaaa tggaatcctc aggcaagact
    18421 cctgcttcca cttcttcatt tttacgaata gcttgaccaa ctgttagctc ttttgcttca
    18481 tcaaaatcaa attgcggttc ttgaccttct tttttatgac gatttcgtct ttttttactc
    18541 atgagtatcc ctttctattt tacctcttgc cgtttgacac gctgaccaaa atattgatat
    18601 agatccactt tcaaggttcc gttgtataac ttacgcttct tatctgcttg gctaccatac
    18661 ttgctttcaa aagcttcatc actagtcagg ataaatttgc tccaagtttt cagcggtgca
    18721 aatacttgcc ccatctcagc atagagcttg gtcactcctg catcatctga caaacgttca
    18781 ccataaggcg gattggaaat gattactcca ttgattttat cggaacgtaa atcctgcacg
    18841 cgcatctgct taaaagtaat atctcctgca acaccagctg cctgagcatt ggccttagca
    18901 atttccacca tgcgagcatc aatatcacag cccatgatat ccaactcaag cttacgttct
    18961 acttttttag ccgcttctgt gcgcacttct tgaatcaagc gatcgctgat ccagttccat
    19021 tcatcaaatg caaaagagcg acgaagacct ggcgccatct ttctagcaat cataactgcc
    19081 tcaatacaga aagtccccga accacaggtc ggatcaatca aaggcttgtc tggataccag
    19141 ttagaaagtt gtaaaatggc tgctgccata ttttccttga taggagcgcc acctttttcg
    19201 gtacgataac cacgtttaaa gaggctagac ccggtcgtat caatcatgac agttgccaca
    19261 tctttgagaa tagagacctc aatcttaaac tctgggccat tctccatcag aggaacccct
    19321 tctgggcgag catagtgttt ctgcaatttc ttgacaacag ctttcttaga aatagcctga
    19381 acactgggct cattgtgaag tttggactta acacatttag cttttgaaat cggtaaccga
    19441 gctccaagtg gtaaataatt ttcccaatct aaagcgaaaa ctccctgaaa tagctcttca
    19501 aaagtcttag ctgggaacgt tcctacgata attttgatac gatctgctgc ccgaagccaa
    19561 aggttggttt cgataatagc tctcacgtct ccttgaaaac gaacacgtcc attttcaacc
    19621 tgacaatcgt agcccaactc tcgcacttca cgaccaacga cagcctcaag ccctgctgcc
    19681 acagttgcaa ttaaattaaa ttcttttttc atgttacagt cttgcaagac ctttctatat
    19741 gtccacttta aaaaatgagg ttgagaaaat ttctcagccc caacctatat gcaattttct
    19801 ataagccatg ttttgttcca gaagtgacta ggaccacttc cttcgataat catctgtcta
    19861 ccactaacag ctctagctga tagcagtcag aatactacgt tcgtttccgc atactccatg
    19921 ccccgaccaa aatttgggtt gctagcttga ggggtttacc gcgttccact ctctctgttt
    19981 ccagaaagac tccgtcactg tggcactttc aagcctactc tggcctatcc aaggacttag
    20041 ccatttcaac tgccgtaacg atttctcgtc cctaggctta tggtttcgcc tagcacaaac
    20101 actacaggca tcacagcctg tgctagcatg gactttcctc atgagaagca attctcctca
    20161 cgcgattatc caaaaattgc acatctcaaa taactactta aaaatctgag ttatctaaaa
    20221 tttgtttacc aaaaacttct ttttccaatc tattcaggcg tttcaaaata tcaaaattcg
    20281 tcatagaact tgtaattgcc gcttcaaggg gttctgcttg aactggtgaa ggtttcggtt
    20341 tacgagttaa ttcttccttc aaatccgcaa tttcctgacg aagtgacttg accaaggcag
    20401 cataggtttc atagtccttg atgacatcgt ctaaaaactc gtcaacttct actttattat
    20461 agccacggac ttcacgtcca aactcttgtt caaaaatatc tttcgctgaa aaaataatac
    20521 ttgccatgtc tctctccatt ctcgcttgct agtattatta tataaaaaaa ggcaaacaaa
    20581 aatcaaggtc aaagcttcaa ttttcggaaa aattttcagc aagttcattt aattgatcaa
    20641 atgttaatct ctttataaaa tagtcctctt gatttttcat cttttggtaa aaataagcta
    20701 gttttgtttc attttcttca tcataaaaaa gataggaact agtcgtgttt tccagcaaaa
    20761 actgctggta atctcttaac tgccccttgt gttcatagcg aggataagca tatttgacaa
    20821 agtctacctg cttaaagcga ctcagtttca tctgattacc ttcattccaa ttttccccat
    20881 gggtttcaaa agcaaaaatg gtggccaact ggaaaccgta ttcggttttc atctcctgag
    20941 caacctctaa aacccaatat tcaaaaccca aacttcctgt aaacacaagc caagacaccc
    21001 catctgctgc catagcctct aaatctttac gtatcgcttt tttaatcaat ttaagacgag
    21061 gatccttatc agaaaataaa cccaaatcaa aagtagaata gcctaaaacc aaagctgtag
    21121 ccatttttaa ccctttctgt gcaaattatg gtataataaa gtgatgttat tgtaccaata
    21181 aggagaatta tggtcaacta tccacataaa gtttcatcac aaaaaagaca aacatctctt
    21241 tctcaaccca aaaatttcgc aaatcgagga atgtcttttg aaaagatgat caatgctacc
    21301 aacgactact atttgtctca gggcttggct gttatacata agaaaccaac tcctattcaa
    21361 atcgtacaag tggactatcc acaacgaagt cgtgccaaga ttgttgaagc ctattttcga
    21421 caagcttcaa cgacggacta ttctggcgtt tataatggat attacatcga ctttgaagtc
    21481 aaggaaacaa aacaaaaacg tgcgattccg atgaaaaatt ttcatccaca tcagattcag
    21541 catatggaac aagtccttgc ccaacaagga atctgctttg tccttcttca cttttcttct
    21601 cagcaagaaa cctacttatt gccggcattc gatttgattc gcttctatca tcaagataag
    21661 ggacaaaaat caatgccact tgaatatatt cgagaatatg gatatgaaat caaggctggt
    21721 gccttccctc aaattcctta tctcaatgtt atcaaagaac atttattagg tggtaaaaca
    21781 agatgaacaa accaacgatt ctgcgcctaa tcaagtatct gagcattagc ttcttaagct
    21841 tggttatcgc agccattgtc ttaggcggag gagttttttt ctactacgtt agcaaggctc
    21901 ctagcctatc cgagagtaaa ctagttgcaa caacttctag taaaatctac gacaataaaa
    21961 atcaactcat tgctgacttg ggttctgaac gccgcgtcaa tgcccaagct aatgatattc
    22021 ccacagattt ggttaaggca atcgtttcta tcgaagacca tcgcttcttc gaccacaggg
    22081 ggattgatac catccgtatc ctgggagctt tcttgcgcaa tctgcaaagc aattccctcc
    22141 aaggtggatc aactctcacc caacagttga ttaagttgac ttacttttca acttcgactt
    22201 ccgaccagac tatttctcgt aaggctcagg aagcttggtt agcgattcag ttagaacaaa
    22261 aagcaaccaa gcaagaaatc ttgacctact atataaataa ggtctacatg tctaatggga
    22321 actatggaat gcagacagca gctcaaaact actatggtaa agacctcaat aatttaagtt
    22381 tacctcagtt agccttgctg gctggaatgc ctcaggcacc aaaccaatat gacccctatt
    22441 cacatccaga agcagcccaa gaccgccgaa acttggtctt atctgaaatg aaaaatcaag
    22501 gctacatctc tgctgaacag tatgagaaag cagtcaatac accaattact gatggactac
    22561 aaagtctcaa atcagcaagt aattaccctg cttacatgga taattacctc aaggaagtca
    22621 tcaatcaagt ggaagaagaa acaggctata acctgctcac aactgggatg gatgtctaca
    22681 caaatgtaga ccaagaagct caaaaacatc tgtgggatat ttacaataca gacgaatacg
    22741 ttgcctatcc agacgatgaa ttgcaagtcg cttctaccat tgttgatgtt tctaacggta
    22801 aagtcattgc ccagctagga gcacgccatc agtcaagtaa tgtttccttc ggaattaacc
    22861 aagcagtaga aacaaaccgc gactggggat caactatgaa accgatcaca gactatgctc
    22921 ctgccttgga gtacggtgtc tacgattcaa ctgctactat cgttcacgat gagccctata
    22981 actaccctgg gacaaatacc cctgtttata actgggatag gggctacttt ggcaacatca
    23041 ccttgcaata cgccctgcaa caatcgcgaa acgtcccagc cgtggaaact ctaaacaagg
    23101 tcggactcaa ccgcgccaag actttcctaa atggtctcgg aatcgactac ccaagtattc
    23161 actactcaaa tgccatttca agtaacacaa ccgaatcaga caaaaaatat ggagcaagta
    23221 gtgaaaagat ggctgctgct tacgctgcct ttgcaaatgg tggaacttac tataaaccaa
    23281 tgtatatcca taaagtcgtc tttagtgatg ggagtgaaaa agagttctct aatgtcggaa
    23341 ctcgtgccat gaaggaaacg acagcctata tgatgaccga catgatgaaa acagtcttga
    23401 gttatggaac tggacgaaat gcctatcttg cttggctccc tcaggctggt aaaacaggaa
    23461 cctctaacta tacagacgag gaaattgaaa accacatcaa gacctctcaa tttgtagcac
    23521 ctgatgaact atttgctggc tatacgcgta aatattcaat ggctgtatgg acaggctatt
    23581 ctaaccgtct gacaccactt gtaggcaatg gccttacggt cgctgccaaa gtttaccgct
    23641 ctatgatgac ctacctgtct gaaggaagca atccagagga ttggaatata ccagaggggc
    23701 tctacagaaa tggagaattc gtatttaaaa atggtgctcg ttctacgtgg agctcacctg
    23761 ctccacaaca acccccatca actgaaagtt caagctcatc atcagatagt tcaacttcac
    23821 agtctagctc aaccactcca agcacaaata atagtacgac taccaatcct aacaataata
    23881 cgcaacaatc aaatacaacc cctgatcaac aaaatcagaa tcctcaacca gcacaaccat
    23941 aacatttatc atccagattt ttctgggtga ttttttcata gcactattgt atttatgtgc
    24001 ttaacaaaag cctgagaaga tatcttctca ggctttttct gtactataaa cctcattgga
    24061 aaagatagag actgcttccg taatcttgtt aagaggtttt actaaatact agtctttctt
    24121 cgtttttact acaaagagag cagatagggc taggctaaca cttgctagga agagggctgt
    24181 gtcagattga ctctcacctg ttgctggcaa gatttgttca ggtgtttctg gtctagctat
    24241 ttcttgctta taatctggcg tcttaccttg ctcggaagct aaagatctaa gtttaaactc
    24301 aggtttctct acagttggag catctggttt cgtagcagaa tcttttaatt ggttgagata
    24361 atctgcaaag tattccatca ttctttccgt caagagatgg ttatccgtcg catatttcat
    24421 gcttgcctga acgctagcta cttcctcttg attgtctttg tctgttaatt tctgagcctt
    24481 aaccaaagct gcttcatagc ctgacaagtc aagaggtgtt tctgctacct gtggacgagt
    24541 aaagataagt tccgctgcag attggtattt atctccacca tctccgtatg tcttggtacc
    24601 agtaaggaca attttcttag ccttgattgt cttaccaaag tcaatatctt ttggtttgtt
    24661 gttatttggc caatcagttg cagtaaaggt atgctccttg ccagactcat ctgtcacaac
    24721 aagtttcaca tctcgcaagt taccatttga acctgatcca cgtggaacat aacgaagtcc
    24781 agtgatttca gttggttctt tcaagaccat ggttgcaggc ttgcctacat ctcctccgcc
    24841 ccatgatgta tgccatagac tagacacatt gccatcaaag gcatttgcaa gaccttcttg
    24901 agcctgagca ggagctgtaa gacttgcaaa gtcatctgct accaaagccg ttttcttctg
    24961 aaccaaagca ttcttcaaag cttcaatctt ggcaatctct gcacgcgctt cttccacact
    25021 gatatcatca tcggcctgac tgaggttaaa gaccgcctct ttcaaagcat ccatagactc
    25081 tttggtgtag ttagtcatgg caaccgttgg caagtagttc ttcagagcat tttctgtcaa
    25141 catcttacct gttagggtaa tttcttcgat ttgaagatta tccatcatga agtcgttata
    25201 accacggaag ttggcatttc caccagaatc accacgagta ttacttgcat ttccagttga
    25261 gtagatacct acccaagtat ctcctgtttc tgcacctgtc acgaggaagg ttgccttctt
    25321 ggctttcttg gaatctgtcc aagtatttgg caattcatgc atttctaagt tgcttgcttg
    25381 agtgccacga cgacctgact ggaattctcc cttaccgact acaaaagcat aggtattatc
    25441 tgaacctgct tcgtattcaa aggttacacg gtaggtctta ccagcttcaa agcggaagtt
    25501 ttgtgggatg gtttggtaaa ccaagttacg acggctaacc agtccattgg tcttgagtga
    25561 ccaatttcca tcgataacat catcaacttt cttaccgttc caaccacgtt gtgtatatgg
    25621 atcatgcttt tcagacaagt gagtgcggtt gtcttcaaca ccttcgacac cacccactac
    25681 gaatgggaag ataccctgag caacattttc aaagtcttgt ttgaaggtgc ctttacctgt
    25741 atcatggttt tctccgtaca tgcttgaatt gttttcaaag gtacgaattt catcaaagta
    25801 agttgcttga tcaccagctt cgcgacttaa agtaagagta acatttgata cgtccgatcc
    25861 agttgtaaag aaggcgtaca tgttttggaa gtaacttgta ttgtcaactg tagcattgtc
    25921 acgacgtgta ttgtgggcgt aggccttaac atagttgaga gcgagagact tattggtata
    25981 agtagtcact tctttttcac cagtgtttac agtgatgctc gccttggcat tactacggtt
    26041 atcgacaccg acataaacgg catacttggt atttggtttc aaaccagtta atttctgagt
    26101 gagactaact ttttctttgt ttccttgaat acgaagcata tcgtttgccc cttgagactt
    26161 gacaatttct gccttagaag catcgcctga aatggtccag tgtttcaagg taccgctatt
    26221 aaatccttga tcatagatgt gcatgccttc actccatgac atttcaggat tggtttgttt
    26281 cgaacgatag aaaacgtatg gttgatttgc tagaagatct agggtaattt taccatcttt
    26341 tacagttagt tcttgctctt ctgtcttacc ttggtcagtt agcttgtaaa ggtaaacctt
    26401 gctctttgcc caatcacttg gaagggtcca agttgttgca ccggcctgcg tattgaagta
    26461 gtacatcttt tccttatcag tagaaagttt cttaccattt gcatcccagt tccaaggagt
    26521 caagtaagct gaaccatctt ggatgacacg tccgttgagc gttactgtac gtttgcgata
    26581 ttgtggacta ttgacatcat ttgacttacg agttacaact actttattat tgttagcatc
    26641 taccaattcc actcgcattt ctggagtcca tttataggtg ctaccgttat cggtcatagt
    26701 caccggtgta ccattttccc atttacttac agtgaagtgt tggaagtact tggtcatgac
    26761 gtcatgggca aataagttag ttacatagcc attgtagtca cttcttcctt gccagccttc
    26821 aaagtctttc atgctgtagc cacctagcag tggatagttg gctgcaccac cataacttct
    26881 gtagtcccct acccaagcat ctttttggtg gttacggata aagcgggtga tggcactgtt
    26941 gataccttta ttggtgtagc caccgtaggt caagtcagct gcccagtgat ggaaggtaga
    27001 gtcgtactca ccaccatggc cccactcgat cgcaaagcgc cagccttgtt tgttaatttc
    27061 tttagcaaga acgtgggtag cccaggcacc gttatcacct gattgaccat taccccaaac
    27121 gtccacatag ataaagtcga gaccgtcacc aagttttttc ttcaaatctt cccaacgtgc
    27181 caaacgacca tgagctaggt cataggcagc atcaatgttg ataccttgat ctagccagtt
    27241 ccaaccatag ctatagcttc catctggatt cttacggaga attttttcat tgaaatattt
    27301 agactcagga taagtttctg aagcgttaac atggatacct agatgagctc catatttctt
    27361 agccttctca attagggtct tgaagtcttc gacaccaccg atacgcttac caatatcagc
    27421 atagttcaag tgaccagagt catgaccttc actaccatat cctttaagga gaacaccttg
    27481 cccaagacca tctgtgtgga gattgatttt cttgatacca tccaaggtca taaggaatgg
    27541 attttgtgct tgagaaccaa agttcatcgc gatacggtaa gctgtgatat ccttaacttt
    27601 ttcccaacct tgagggttgt tcataatgct acgataagca atggcaccat cctgccaatc
    27661 aactttcttg tctgcattgg catcttcagt gataacaacc ttagcacttg gaagttcctt
    27721 cgtgtattct gggaaaacaa tgcccttata agctttttcc cattgccatt cagagctgtg
    27781 gattcctaca tagttggcat ttccgactgt ttctttataa gctgtcaaac gagtccagtc
    27841 attcgaacca ccaccatagc tgttttgaga gttactccaa acaccagcag caagcttatc
    27901 tgtagaaaca aatccataca tgtaaccctt agccaaatcc ttcattggat tggttacatc
    27961 gatatgatca tctccgctga catgtgtatt gtttgacatg gttgccccat caaacttagc
    28021 accagtttga tcactagaaa cagagactaa agcattgccg aggaaactaa tagaagaaag
    28081 tagttttctt tcgtcatcga tcttttgacc tggagtgact tgattgtggt tgacaatctt
    28141 ggtcacatca aagtgcaatt gattgtccac aacttgcaag cgtactgtca tttccgcatt
    28201 gattaagtga gcatcatcgc gaagcttcat caagtactct gctgttgtct cattgatttt
    28261 cttataagtg acttcagggg tgattcggtg gttattgata aagacttggt tgaactgttg
    28321 cacctgtcct ggcaaagtat gtccattcaa ggtgtattcc ttgacacgag ggaaggcttg
    28381 gtcaatcact gctttgagga ccttagactg aatcgtgtca taagtcacct tgctatcatc
    28441 aacttcagga cctgtttctt tttcagcagg ggtatcctct gtttttaccc cctcttggtt
    28501 atccgtttta acgctaacaa ctgttcgctc atcgtcataa gagcccgcct tgagaagaat
    28561 cttcttctca tttttaagat ggtcattgac cgcagctggt agagtcactg tgtcaaagag
    28621 attgacatcg ttattgctgg catttagctg accgtctgac ttgagagtga tagaaagacg
    28681 gtttattgat cctgtttcag gagcagcaac acggttgcct ttataccatg tgctattacc
    28741 tggagttttg tattcccaga accagccatc cttgtcataa ccgacaaaaa cattattatt
    28801 ggtatcttta aatttcaaga agacaccaaa gcgtgatttg cccttttcag aatcttcttt
    28861 gaaggttaaa tcaacagttg catttccatt ggcatcaacg gtcaagccct tcttttcaaa
    28921 cagggctggt ttgcctgcgt tatcattttg agcagttgag gatagttggt tgtagcggac
    28981 acctttttct tctcggatag tgactgttcc ctgttgttct tttttctcta ccgtttgcca
    29041 ttcaggagtt accgtcttag gggttaccgt cttaggggtt tcaggtttag cagctgcagg
    29101 tttatcctct tttggttttt cttcagccgg tttttctttt tcaagtgcta atagttcttc
    29161 ttctgtctta ggtccatctg taacttctgg agaaccttgg tcttctccca ccttaggcgc
    29221 ttcaaaatca cgcccatcat tctcttttgc tgttgcaaga gcagtagcta aatcagctgg
    29281 taagttcgcc gtggaaccag actgcacgct atctgcaaga accggacttg tcccaaagaa
    29341 tgcagctcca atcataacag aagcaacacc taatgaaaat ttccgaatac tatatttaca
    29401 acgtttttca aataatcctt tattcataaa cttctaaatc ctttcatttt tgagcaagcg
    29461 tttacatttc ctttttaaaa aatactcctt cctctgaaaa tgcaatgctt aaccctgata
    29521 aataaaaata attatacttt taatataaca aataataact gagaaagcaa taggaaacaa
    29581 gtaaaattaa caaaaatttt ctctattctg acaaaaagag gctccaactt ttgggggtca
    29641 gtacatttag aatctttctt tacaaatgta aaaaaggatt cagcattcaa gagaaatact
    29701 aaatcctttc ttatattttg caacagttat ttcacatgtt ttgcgagatc ttcttgagcc
    29761 tttttattag actcttcttt ttctttcatc catttttcct gagctttttg gtattcatct
    29821 acagtgactg ccttgtcttg aagttccaag tatttatata agattggttc acttgtacct
    29881 ttatttcctg acaatgcaaa tggtattgta aatggtacca tcttagacaa gattggacgc
    29941 cctgtacgag atgtagttgg aataatcaaa gcactatctg tcaaccaagc ttgggctgca
    30001 gcgtatttat catagcgttt agcaacatct gtagcctcat caccagcctc agtaaccaat
    30061 ttttcgtagt catatagacc tactttttta gcagctacat tatcttcccc tgagtcaaac
    30121 cctaaatatg ttttagtact ttctcctaca gatggtttga tgatatcaag gtaggttgat
    30181 ggatcggcaa agtctggacc ccaaccgaca ttatctgata aatcccagtc ttcgccagca
    30241 gcattttcag caaaatatgt aatattgttt acttcgtctt tttgtagttg ttggatatca
    30301 ataatgacat tatcagctcc taaagttgct tccaaggatt gtttcataga ttggacgcgc
    30361 tgaacttttg tagttgctgt ctggtcaact ggcatatcca aatgaattgg gaaagtcaca
    30421 ccttctgctt gtaaggctga tttagcttta gcaaattcag ccttggcttt ttctggattg
    30481 taaagaccat cctgagaatc tgcaagatta acatccttcc attcatcccc ataagtaacc
    30541 aatttctctt tgaccatatc gccaaagttt ttaccatctg cttgaacaaa tgttggtgga
    30601 acaaagatat tacgtaagat tttgcttgct ccagtttgtc cattcaactg agaggcatag
    30661 gctgtacgat caaaaccaaa ggcaatagcc tgacggaaat ccttgtttaa gagagccttt
    30721 ttagtcgatg ccttttgttc gtcgctggtc ttagatgtgt atttatagga ctgacggtca
    30781 atatttgtac caactaaata cgtaatagag tcttgttgag tatagacaat attgtccttc
    30841 atactcttct caagctctgc gaaacttgca cttgttggat agagacgagc tgctgtaagg
    30901 ctaccatctt taaagttttc tgcaggtttg ctggtatctt gaccatccca gaatgacaat
    30961 ttaactttgt caatatgcac attgtcctta tcccagtagt tcggattttt cgcaaattca
    31021 acagaagatt tggtcacaat ggatttcaac aaataaggac cgttatacaa gagactattt
    31081 ggatccgtag ctttggcaaa atcatcccct tttgaattca aaaactcttc attaactgga
    31141 gccattactc ccattgttgt cttagaattc cagaagcttt ctggtttgtt caaagtgtac
    31201 tgaactgtct gttcatccag agccttaatt cctacttgtg agaaatcttt gatttcccct
    31261 tttacatagc catccaatcc tttgattgat tcttgaacaa ggtaaagagc atctgatttt
    31321 ttatcagcag catattttag tcctgttaca aagtcttgag ctttgactgc cgcgtattct
    31381 tcaccttcag aagtatacca ttttgcatcc ttacggatag tataagtgta agtcaatcca
    31441 tccttggata cagaccaatc ctcagccata gacggcacaa agttcccgta gcgatcattt
    31501 tctagcaaac catcaaccac gttactggta atatttgctg tcgcagcctt agcagttgtc
    31561 aaatagttga ggttatcagg gtctgtctca taaatgtatg agaatgtctt ctcaccttta
    31621 gtgcttgaac ctgatccaga gcatgcagct aaagtagtcg ccgccaataa tgtcacgccc
    31681 gcaagggcaa gtagttttga acttttcatc attttctcct ttaaaacttt ctctccatta
    31741 tagactcttt tcagaaagat gtcaacagaa ttttcagaat ttttgaaaat tatttttcaa
    31801 acaacatctt tgcaaaaaat atgaatatcg taaccgccca ataacgaggt ctattgaaaa
    31861 atctccagat tagtgaactc acggatagtt cctaatctgg agatttctta tttgcacttt
    31921 tcttgtacaa ctttagtcca tggtaaatag gcctctaaaa cctctttgtt tacgagagtt
    31981 tcctcgtttg gaagacatt
//
LOCUS       DAYYYC010000023        29920 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.023, whole genome shotgun sequence.
ACCESSION   DAYYYC010000023 DAYYYC010000000
VERSION     DAYYYC010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29920
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.023"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            426..686
                     /locus_tag="ACHBV5_001100"
     CDS             426..686
                     /locus_tag="ACHBV5_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966908.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            640..860
                     /locus_tag="ACHBV5_001101"
                     /pseudo
     CDS             640..860
                     /locus_tag="ACHBV5_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1179..2108
                     /locus_tag="ACHBV5_001102"
     CDS             1179..2108
                     /locus_tag="ACHBV5_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9966909.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGTLWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            2122..3045
                     /locus_tag="ACHBV5_001103"
     CDS             2122..3045
                     /locus_tag="ACHBV5_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM9966910.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            3255..4730
                     /locus_tag="ACHBV5_001104"
     CDS             3255..4730
                     /locus_tag="ACHBV5_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM9966911.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            5002..5988
                     /locus_tag="ACHBV5_001105"
     CDS             5002..5988
                     /locus_tag="ACHBV5_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFM9966912.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEEREQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            6263..7123
                     /locus_tag="ACHBV5_001106"
     CDS             6263..7123
                     /locus_tag="ACHBV5_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HFM9966913.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFERVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(7301..8365)
                     /locus_tag="ACHBV5_001107"
     CDS             complement(7301..8365)
                     /locus_tag="ACHBV5_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HFM9966914.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(8428..9339)
                     /locus_tag="ACHBV5_001108"
     CDS             complement(8428..9339)
                     /locus_tag="ACHBV5_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HFM9966915.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(9332..9925)
                     /locus_tag="ACHBV5_001109"
     CDS             complement(9332..9925)
                     /locus_tag="ACHBV5_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFM9966916.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYATRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            complement(9912..10238)
                     /locus_tag="ACHBV5_001110"
     CDS             complement(9912..10238)
                     /locus_tag="ACHBV5_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFM9966917.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            complement(10377..11543)
                     /locus_tag="ACHBV5_001111"
     CDS             complement(10377..11543)
                     /locus_tag="ACHBV5_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HFM9966918.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            11601..12758
                     /locus_tag="ACHBV5_001112"
     CDS             11601..12758
                     /locus_tag="ACHBV5_001112"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFM9966919.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKEDIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINQNML"
     gene            12800..14650
                     /locus_tag="ACHBV5_001113"
     CDS             12800..14650
                     /locus_tag="ACHBV5_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HFM9966920.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(14736..14993)
                     /locus_tag="ACHBV5_001114"
     CDS             complement(14736..14993)
                     /locus_tag="ACHBV5_001114"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966921.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVADRTDEVRSKHCFKVVDGTDEVR
                     SKHCFEVADRTDEVRSKHCFEVVDRTDEVSNHIRQGDVDVV"
     gene            complement(15043..15675)
                     /locus_tag="ACHBV5_001115"
     CDS             complement(15043..15675)
                     /locus_tag="ACHBV5_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFM9966922.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(15697..16569)
                     /gene="sdaAA"
                     /locus_tag="ACHBV5_001116"
     CDS             complement(15697..16569)
                     /gene="sdaAA"
                     /locus_tag="ACHBV5_001116"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFM9966923.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(16578..17249)
                     /gene="sdaAB"
                     /locus_tag="ACHBV5_001117"
     CDS             complement(16578..17249)
                     /gene="sdaAB"
                     /locus_tag="ACHBV5_001117"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFM9966924.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            17491..18063
                     /locus_tag="ACHBV5_001118"
     CDS             17491..18063
                     /locus_tag="ACHBV5_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFM9966925.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(18116..18442)
                     /locus_tag="ACHBV5_001119"
                     /pseudo
     CDS             complement(18116..18442)
                     /locus_tag="ACHBV5_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268159.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            19194..19565
                     /locus_tag="ACHBV5_001120"
     CDS             19194..19565
                     /locus_tag="ACHBV5_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HFM9966926.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
     gene            19573..19785
                     /locus_tag="ACHBV5_001121"
     CDS             19573..19785
                     /locus_tag="ACHBV5_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966927.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            20159..20284
                     /locus_tag="ACHBV5_001122"
     CDS             20159..20284
                     /locus_tag="ACHBV5_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966928.1"
                     /translation="MATITNALNIVATVAEVFSLGGAIAYGLDIVDGKFDGYLWA"
     gene            20265..20510
                     /locus_tag="ACHBV5_001123"
     CDS             20265..20510
                     /locus_tag="ACHBV5_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966929.1"
                     /translation="MGIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            20667..21725
                     /locus_tag="ACHBV5_001124"
     CDS             20667..21725
                     /locus_tag="ACHBV5_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966930.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEDGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            22039..23016
                     /locus_tag="ACHBV5_001125"
     CDS             22039..23016
                     /locus_tag="ACHBV5_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966931.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKSLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            23393..23767
                     /locus_tag="ACHBV5_001126"
     CDS             23393..23767
                     /locus_tag="ACHBV5_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HFM9966932.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            23774..23956
                     /locus_tag="ACHBV5_001127"
     CDS             23774..23956
                     /locus_tag="ACHBV5_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966933.1"
                     /translation="MGIKMEKIFVIIFFVCLFISSITFLAYDFVSEEIKKLIIWMNVV
                     FLILIIAMIIYPKLRK"
     gene            23975..24877
                     /locus_tag="ACHBV5_001128"
     CDS             23975..24877
                     /locus_tag="ACHBV5_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966934.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            24933..25286
                     /locus_tag="ACHBV5_001129"
     CDS             24933..25286
                     /locus_tag="ACHBV5_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HFM9966935.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKSDCQGICAALAMSPGT
                     FIALAGSAVLTKKLINYIKFGGLGGWLIGAAAGVLATAAGKIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            25283..26011
                     /locus_tag="ACHBV5_001130"
     CDS             25283..26011
                     /locus_tag="ACHBV5_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966936.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            26490..26687
                     /locus_tag="ACHBV5_001131"
     CDS             26490..26687
                     /locus_tag="ACHBV5_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966937.1"
                     /translation="MKHFFAGIGEIKLVGYLLYICVGLAPLFHIYVIGSELSFVKIVL
                     SILGVIFVSMLTIARIYRTFL"
     gene            27164..27646
                     /locus_tag="ACHBV5_001132"
     CDS             27164..27646
                     /locus_tag="ACHBV5_001132"
                     /inference="COORDINATES: protein motif:HMM:NF037419.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR4 domain-containing protein"
                     /protein_id="HFM9966938.1"
                     /translation="MDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLFGLHKITR
                     DYASQTKPAIQDGVFILEDFRNILLYNDVIERISLYEFIGDIFYSKITSCCIVAKDLS
                     KNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTDVKEMKWL
                     "
     gene            27933..>29920
                     /gene="pspA"
                     /locus_tag="ACHBV5_001133"
     CDS             27933..>29920
                     /gene="pspA"
                     /locus_tag="ACHBV5_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HFM9966939.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTLVRAEEAPVANQSKAEK
                     DYDAAVKKSEAAKKDYETAKKKAEDAQKKYDEDQKKTEEKAELVRKADEKRQKANLAV
                     QEAYVKFQEAQREFNESPSRKKSDAKKKLDDASAHIEEVKLKQKEADANFNKEQAKVI
                     PEASDLAVTKQKAEEAKKEAEVAKEKYDKAVQEVEVEKNKILEQDAENEKKIDVLQNK
                     VADLEKGIAPYQNKVAELNKEIARLQSDLKDAEENNVEDYIKEGLEQAIADKKAELAT
                     TQQNIDKTQKDLEDAELELEKVLATLDPEGKTQDELDKEAAEDANIEALQNKVADLEN
                     KVAELDKEVTRLQSDLKDAEENNVEDYVKEGLDKALTDKKVELNNTQKALDTAQKALD
                     TALNELGPDGDEEETPAPAPKPEQPAEQPKPAPAPQPAPAPKPEKTDDQQAEEDYARR
                     SEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAPKTGWKQENGMWYFYNTDGSMATGWLQ
                     NNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGW
                     LQYNDSWYYLNANGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMAT
                     GWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMA"
BASE COUNT         9462 a         5010 c         6093 g         9355 t
ORIGIN      
        1 agtgtattga atttataaca gtacaccttg gctgctaaaa tatttctata aattaatttg
       61 actttcctga tagagttgtt cacatcttat ttcaaatcac tataaaagct ctataatctc
      121 tttattaaga tttgcccatc agacgaaata taatggattg aaactagaat agtacacatc
      181 tacttctaaa acattgttag aaatcgattt gactgtcctg atcgatttgt cctgttcttg
      241 tttcatttta ctatagaacg atttgaaggc gtttatgata tttagctgta cgagagtctt
      301 ttaaaagtgt tttgatagtt tggatttctt ctttagttga tttcatatca ctgttatata
      361 atgctttttg attttagtct agtattagta agcagactca aaccttagaa aatcttttga
      421 gatcattgac aggtgtatcg aatcctacca cagattcagc acgtctggtt ttggcagagg
      481 ctaagaaagc ttttgcagat gatagtttga cagagcaagg tttacgtgat attttgcaaa
      541 cagtcaaaga tgccattgct tccctagagt ccattaagga aagccagtca gcaactaagg
      601 atggaggaca aacagcgggc aaagaaacag caggagaaga tgagtctgca aatcaaactc
      661 aagaaattag ccaaggaatt aagtaaactt cttaaagact caaaccttga aacagtagat
      721 aaggatgtcc ttgaaaactc tcaaaaagaa cttcaaaaag cagttttgtt cttggcagat
      781 gaaaaagctc tgagcatact gaagcagagg tgattgataa tcttaaagag gttattgcta
      841 agttgaaagc aaacgcctaa taacatatta aaaatctcca gattaggaac tatctctgag
      901 ttccctagtc tggagatttt tcagtatacc ccgttgttgg atgcttataa cagagtgacg
      961 ccatcactgg gctaatagag ataaaataaa caattgattt aggacatttg tttgatagtg
     1021 gtgataaagt tttaaatctg ctacataatt tgtggagttt tttctataat taggagttta
     1081 acctaacctg caaataggag tatactaata atgtaatcgt tatcaaaagt ctaaaaaaga
     1141 atttttagat ggatatcaaa ataaaaaggg aggaaattat gaaaaagttt tcaaaaacat
     1201 tgagagacaa ctggatcttt ctcttgatgg ttttgccagg gacactctgg ttgattctat
     1261 tcttttacat tccagtattt gggaacgtgg ttgccttcaa agactaccac atgaccagta
     1321 atggtttcat agatagtatc ataaatagta aatgggtcgg actcgataat ttcagattct
     1381 tatttagttc aagagacgcc tttattatca cacgaaatac tgtcctctac aatcttggct
     1441 ttatctttct aggtttagtt gtatctgtag ggattgccat tatcctcagc gagctccgtt
     1501 ctaagagaat ggtgaagatt ttccaaactt ctatgttgtt cccttacttc ttgtcttggg
     1561 ttatcatcag tttctttaca gatgccttcc taaatattga taaaggggtg ttcaatcatc
     1621 tattggaaag tcttggtctc aaagaagtca atttttacgc tgacctgggc atctggccct
     1681 atctcctact tttcctaggt atttggaaag gctttggata tagcagtgtc atgtactatg
     1741 cgacgatcat gggaattgat ccaacctact acgaagcagc gacagtggac ggagctagca
     1801 agtggcaacg tattcgcaac gtaaccattc ctcagttgac tccgcttgta actgtattga
     1861 ccatccttgc agtcggaaat atcttccgcg cagactttgg tctcttctat caaatcccac
     1921 acaatgctgg tcagctttac aatgtaacca acgttttgga cgtatatgtc tttaatggtt
     1981 tgactcagac agcagatatc ggtatggctg cagcagccgg tctttaccaa tccgttgttg
     2041 gtttgattct ggttatccta tcaaacttgc ttgcaagacg agtcgatcca aactcagctt
     2101 tgttctagaa aggaggagaa tatggcaaaa aagaaaatta aaaaagaaaa aattgataat
     2161 gtcggcattc actccttcag taagaaagca gatatcttct tcagtatcat ttcgggtttg
     2221 attgccctct cttgtatcct accttttgta ttcgttatca ttatttcagt gacagacgag
     2281 aaaagcctcc tccaatacgg ctatagcttc ttcccatccc aatttggctt agacggtttt
     2341 gagtttttgg cacagtttaa ggataaaatc ctacaagccc tcttcatctc tgtctttgta
     2401 accgtagttg ggacattgac aaatgtcttt atcacaacaa cctatgccta cgctatttca
     2461 cggacaacct ttaagtatcg cagattcttt accatcttcg ttctgctcag tatgttgttc
     2521 aacgctggtt tggtaccagg ttatatcatg gtgactcgtg tgcttcagct tggggatact
     2581 gtttgggcct tgattgttcc aatgcttctc tcaccattta acatcatctt gatgcgttcc
     2641 ttcttcaaga agaccattcc agaagccatt ctagaatcgg ctcgtatcga tggtgccagt
     2701 gaagcccgga ttttcttcca aatctgtttg ccattgtcac taccaggtat cgcaaccatc
     2761 acgctcttaa cagctcttgg tttctggaat gactggttca acgcccttct ttacatcaag
     2821 agtgacaact tgtatccatt gcaatatttg ctcatgcaaa tccaacaaaa tatggactac
     2881 attgccaaag cggtcggctt gactggtcaa ctgggagttg ctctaccgaa agaaacaggt
     2941 cgtatggcca tggttgtggt tgcaaccctt ccaatcgcga ttttgtatcc atttttccaa
     3001 cgctactttg taaaaggttt gactatcggt ggtgtgaaag aatagtgctt attgagaaat
     3061 aacatttctc agttcccaac ttcccttgtg tgaagttaat actcttcgaa aatcaaattc
     3121 aaaccgcgtc aacgtcgcct tgccgtactc aagtacagcc tgcggctagt tttctagttt
     3181 gctctttgat tttcattgag tataagatca ttacattgtt tataagttta aaaataaaaa
     3241 aaggagtttt tatcatgaaa aactggaaaa aatatgcttt tgcatctgct agtgtagtcg
     3301 ctttggctgc aggtcttgct gcttgtggca acttgacagg taacagtaaa aaagctgctg
     3361 attcaggtga caaacctgtt atcaaaatgt accaaatcgg tgacaaacca gataacttgg
     3421 atgaattgtt agcaaatgcc aacaaaatca tcgaagaaaa agttggtgcc aaattggata
     3481 tccaatacct tggctggggt gactatggta agaaaatgtc agttatcaca tcatctggtg
     3541 aaaactatga tatcgccttt gcagataact atattgtaaa tgctcaaaaa ggtgcttatg
     3601 ctgacttgac agaattgtac aaaaaagaag gtaaagacct ttacaaggca cttgatccag
     3661 cttatatcaa gggtaatact gtaaatggta agatttatgc tgtaccagtt gcagccaacg
     3721 tagcatcatc tcaaaacttt gccttcaacg gaactctcct tgccaaatat ggtatcgata
     3781 tttcaggtgt tacttcttac gaaactcttg agccagtctt gaaacaaatc aaagaaaaag
     3841 ctccagacgt agtaccattt gctattggta aagttttcat cccatctgat aattttgact
     3901 acccagtagc aaacgggctt ccattcgtta ttgaccttga aggcgatact actaaagttg
     3961 taaaccgtta cgaagtgcct cgtttcaaag aacacttgaa gactcttcac aaattctatg
     4021 aagctggcta cattccaaaa gatgtcgcaa caagcgatac ttcctttgac cttcaacaag
     4081 atacttggtt cgttcgtgaa gaaacagtag gaccagctga ctacggtaac agcttgcttt
     4141 cacgtgttgc caacaaagat atccaaatca aaccaattac taacttcatc aagaaaaacc
     4201 aaacaacaca agttgctaac tttgtcatct caaacaactc taagaacaaa gaaaaatcaa
     4261 tggaaatctt gaacctcttg aatacgaatc cagaactctt gaacggtctt gtttacggtc
     4321 cagaaggcaa gaactgggaa aaaattgaag gtaaagaaaa ccgtgttcgc gttcttgatg
     4381 gctacaaagg aaacactcac atgggtggat ggaacactgg taacaactgg atcctttaca
     4441 tcaacgaaaa cgttacagac caacaaatcg aaaattctaa gaaagaattg gcagaagcta
     4501 aagaatctcc agcgcttgga tttatcttca atactgacaa tgtgaaatct gaaatctcag
     4561 ctattgctaa cacaatgcaa caatttgata cagctatcaa cactggtact gtagacccag
     4621 ataaagctat tccagaattg atggaaaaat tgaaatctga aggtgcctac gaaaaagtat
     4681 tgaacgaaat gcaaaaacaa tacgatgaat tcttgaaaaa caaaaaataa tcagctaaat
     4741 tgatttcgtg tattcattcc taactcctaa aataagaatc actgctttcc tcaggttggt
     4801 ctggggaggg cagtggtttt tttggcacaa ggatatagat atccatgttt tctcttgtcc
     4861 ttattttaac cattcaggaa atttcgagaa ccctctacaa tttccagtca aataaattgc
     4921 attcgttttc tcaagcaggt atactagtat ggataaataa aaaatttaga aaatttaaga
     4981 atagaaaaga gaacaaatct tatggcaaaa gatattcgtg tcttacttta ctacctttat
     5041 actccaattg aaaatgcaga gcaatttgct gcagaccact tggctttctg taaatcaatc
     5101 ggccttaaag gccgtatcct agtcgctgac gagggaatta acggaacagt ttcaggtgac
     5161 tatgaaacaa ctcaaaaata catggactac gttcacagcc tcccaggtat ggaagatctc
     5221 tggttcaaga ttgacgaaga aagagaacaa gccttcaaga agatgtttgt tcgctacaag
     5281 aaagaaattg tccaccttgg tttggaagac aacgactttg acaatgacat caacccactt
     5341 gaaacaacag gtgcttactt gtctccaaaa gagttcaaag aagcgcttct tgataaagat
     5401 accgttgtcc ttgacacacg taacgattat gagtacgacc taggacattt ccgtggggct
     5461 attcgcccag atattcgcaa cttccgtgag ttaccacaat gggtccgtga taacaaggaa
     5521 aaattcatgg acaagcgtgt cgtggtttac tgtacaggtg gcgttcgctg tgagaaattc
     5581 tcaggctgga tggtccgtga aggctacaaa gatgtcggcc aattgcacgg aggaatcgca
     5641 acttacggta aagacccaga agttcaaggt gagctttggg atgggaaaat gtacgtcttt
     5701 gacgagcgta ttgccgttga tgtcaaccat gtcaacccaa ctatcgtagg gaaagactgg
     5761 tttgatggaa caccatgtga acgttatgtc aactgtggaa atcccttctg taaccgtcgt
     5821 atcttgacat cagaagaaaa tgaagacaag taccttcgtg gatgctcaca cgagtgccgt
     5881 gttcacccac gtaaccgcta tgtttcaaaa aatgaattga cacaagctga agtgattgag
     5941 cgcctagccg ctatcggtga aagcttggat caggcagcta ctgtataaga tcaaacagtc
     6001 cttaggggct gtttttctat gctttgtact caaaaatcta atactcaatg aaaatcaaag
     6061 agcaaactag gaagctagct gcaggctgct caaagcactg ctttgaggtt gtagataaga
     6121 ctgacgaagt cagttacata tatctacggc aaggcgaagc tgacgcggtt tgaagagatt
     6181 ttcgaagagt ataaagtttg tttttgtatc tttcagaaaa ataaggtata ctgtatgtaa
     6241 acgatttcaa aggagtccag ttatggcgaa aacatttttt attccaaata aacagagcat
     6301 tttaggagaa caagagattt tgaatgccaa gtcgatcttg gccttgctag acggtttgga
     6361 gtcacatagc tatgatgtag tctatctccg tcagcctctt aatcgtctcg aatatatcga
     6421 gtgtgcgata gtggggcaat cacaatttct ctttaaggtc agttatgctg atggtcaaaa
     6481 ggcttaccgt gtcgatcttc ctgacctact aacaaagaca gactggcaga ttatcaagtc
     6541 atttttagat gctttgcttg cttatacagg gactgatatt gaagggctag atggttttga
     6601 ttttgaagct tatttccaag caagtattca agcctatcta gcagaccctg tagctcgttt
     6661 tacgatttgc caaggaattt ttaatcctat tttctttagt cgtgagaact tgaaaagctt
     6721 tttagaggca gatggcttgg ctcagtttga agcgcgtgtg cgtgcggttc aagagacaga
     6781 tgcctacttt gagagagttt ccttctatca ggatggagaa ggaaaagtgc atggcgttta
     6841 ccatctagct caaggagtca agacagtttt accgagagaa ccgtttgttc ctgcagccta
     6901 tattgagcaa ttggtggata aggaagtcca gtgggagatt gacttggttc aaatcacagg
     6961 agatggctct aaaccagaag actatgaagc cattgctcgc ttggactatg caaaattctt
     7021 agaggtatta cccccatctt tttaccacca actagacgcc aatcaaatag aagtgcaacc
     7081 catattagac aaagatttta aaacattagc acaagaaaag taaagcagaa gcaggtcaat
     7141 cgacttgctt ttttgacata gaaaaaatcc tgccaaggat gacaggattg ctactcaatg
     7201 aaaatcaaag agcaaactag gaagctagcc gcaggctgta cttgagtacg gtaaggcgaa
     7261 gctgacgtgg tttgaatttg atttttgaag agtatgaagt ttaaagaaag gccaagatac
     7321 gaagataatc tccaatcagt gccacttcag ctacaaagaa gaggaggata ataactccgt
     7381 tcacaaggac agacaagaat aattgataga aggagtcggt ttcacttgct tgacttggtc
     7441 ttgtaatgat atggagactg gcaagcagaa tgattccaat gctaatcaca cacaagaggg
     7501 ctgtaaatcg taggctatca aagaaagcaa agaaactagc aatagcagtg aggaagattg
     7561 gaattgccaa gagttgacta tattgttgga gaaccttgtc tagcgtccag tccttttcct
     7621 ggtggataaa tcgtctcaca acgaaactac ccaagaggaa tgaaaagaag aagagtgttg
     7681 tcgctactag gatagagatg atagaaaaaa gagttaaagg agctagctgc tcagggaagc
     7741 gactgttaat gcttgctata tgtccatagt aagcatgttt gatgtgatag atactaaaga
     7801 aaaaggaaga tgcagaaaac agaatgagca agagaaaggc tgtgtaactg tgtgtgatac
     7861 ttgtttccaa cttacttgta ggagatttga tcgcttccac tagccaagac caaaaatcaa
     7921 gcacttgctc tttccattta tccctagatt ttggagcttg gtcggggata taaggacttt
     7981 ctaaagattt actgataaga agtggctctt tcgtggttgc tttttgctga ggaagagctt
     8041 cttggctctc ttcagctata gtgacttttt ctgtttcttt agaaaggtct ggctcttctt
     8101 cagtagaatt agatgccttc ttttcttcta tttctgttct cgcttcactg tcttcaggag
     8161 cttcaatttt ctcttcttgc tggctttcca attcgacttc agcttgaggg acttcctcct
     8221 ctaactgagt atttttttca attggtgtat cgagatcggc tatcgtttct tcagccttgt
     8281 ctgcaacctc ttgagcttgc tcttcaggct tgttcttgct tgttgttttt acaaaatcat
     8341 tactttcaaa ccattcttgt ttcatggtag aacctccttt ttagttagat aaatatgttt
     8401 ccatagtagc aaatgtaagc gtttttgtca acgtctgctt ggtgtggata ttagatcaat
     8461 attatcatca gatctcgcaa tgagttgatc cttgacatcg gttttttcag ttttgtaagg
     8521 gttgcttaat tccgtacctc ttgattcagg cttttctctt gtgaattgga agatagaacc
     8581 atagttgctt gagatgtccc agttaattcg ttggctttct ttctggtcta ggatgattct
     8641 gagataatct ttggcagtca gttcaacctt gccatggact tggatatttt cagcgtggaa
     8701 gtgattctct gttgactcta gctgactatc tgtaagaact gtatcaaaga tattaacgat
     8761 attgggcgtt gtgagtttac tgtttttgat acgacttcct tcaattcgga ggatatagct
     8821 gtttgtattg agggtcgcat tttcaaggct agcatttatg atggtggttt gtccgcgatt
     8881 ggctgagatg ttgatccctt ttagagttct cccttttggt agtcggagaa taacttcttc
     8941 aaaacgacta gagtagctac ttgcgatatg aagaatccca ccaattccag aagagagaaa
     9001 cggagtttca gacagtttct tatcagtgag actcagagtt ctatcgttct gattggtgat
     9061 aagatcatgg tgagcagaaa gagatggatg gtaagaaatg tggatttgat catcgaaaga
     9121 gtctgtgatg gtgagcgtgt gttggtggag agtaatttct aggttttcga cttccttgcc
     9181 aaaggttagc ttttccgtac ggctatcata gacaggttct ttggacatgg aaagtaggct
     9241 cttaatcccg tcagattgga tacctacaaa aagcaggata aagccgataa cggtagtcac
     9301 cacaccaaag atgagaaatc cttttgtcca tttacgcatg ctgattacct ctctttcctt
     9361 ttttaagaac aaattgtacc agacgaacaa tgagtagacc gaagaagcga gttgcatagg
     9421 aaatgccaag taaaactagc gaagaagcac cgatagccag taaaccagaa ccaaaaatca
     9481 agataaaggc tgatttggct tgggcgagga cagtgaaact ttcaactaaa aataggaatc
     9541 cgccgatgat acccagtatg gaaactgcaa agaaagccag aatgacagtc aaagcggcta
     9601 caagaattgc gaacagggtc acgaggatgg cgattcccag aggaatgccg ataggtgctg
     9661 caaggagggc taacaaggcg atatgtaaaa tttgtcggtt atttttttga gcgggtgctt
     9721 cattgatttt tttatcgaga agattggata gaacttcgtg ggccgcttct ttgggagttc
     9781 ccaaactagc gatgagttct tcttctcctt cgactccagc atcgtcaaag agctctctga
     9841 aatagtccat ggcttcgata cggtcagctt caggtagttt cttgagatag agttctagct
     9901 gagtcaggta ttcagttctt gtcatggcgg atactccctt ctatgatgcc attgatggtg
     9961 tctgtataga gtgcccattc atcttttagg gtcaagagct gctctatacc accgtttgtc
    10021 aaggagtagt atttgcgcat gcgaccttgg aactctctag agtaggttgt cagaaagcta
    10081 ttgccttcca attttttgag aatgggatag agtgtggatt ctttgatatt agcgatcagc
    10141 ttaatggttt ggctaatctc ataaccataa gaatcaccct gctccagtac agccaagatg
    10201 agaaattcaa tcaaggcaga ggatgttgga aagtacatgg gaaacctcct tttctaatgt
    10261 gtaagatttt tatatataat ttttctacac atacattgta catctaaaag aaagccctgt
    10321 caagagaaat gtgtaaaatt tttatatata aaaaacttct agctaaaact agaagtttaa
    10381 aggatcttat ccgctctgtc cactgtaaag agggccacag tcatcaggat atcgatgagc
    10441 aagagggcag ctacagatgg tacccaagag tggaacaggt caaaactgta accaaagagg
    10501 gttggcccaa aggctgctag gatatagcct cctgtttgag ataggccgga caattgggct
    10561 gtcttttcag gggcgcttgt cttgagtgaa aagttgacca tgagataagg gaagagggca
    10621 ctggttgcgg ttccgatgag gagatggatg gcaagccagt aaatgaaatt attgattggg
    10681 aaaaagagca tggaaatgcc gaccacacca gctagtgaaa ccagagtgag catgagctga
    10741 cggttgcgag tagataaact ggttgtcagg cttgggatgg tcattgaaaa aggaatgcta
    10801 atcagagata agatagaagt cagcaagcca gcttcgtgac tggatagacc tgcatggata
    10861 gacatggtag gtaaccaggt catgacggtg taaaagatca aggattgaaa acctgaaaag
    10921 ataataattg cccaaacctg tttattacgc atgaccttta tttgactttt ttgtttggtt
    10981 tgtggagcta gtctatgatt atagcggtga tttgggagcc agaccaaaaa agttgctaga
    11041 cagagtaacg tgaggagaag gataagtcct ttccaagaac tggcttgtgt aatgggcaca
    11101 gctagatagg aagccagagc cgttgcaatc cccatagacg ttacatataa ggtggtcaga
    11161 aaaccaattt tctttggttg attggcttgg ataagactag gaagcaggac attgatgact
    11221 gcgacacttg ccccaaccat caaggttcct agatagagca ggggcagatt gattagtcga
    11281 ataagtgagc cgatggtcaa gaagaagagg ctgtaggtga agagatgctc caagccgatt
    11341 ttctgagcca gttgggtaga aaatggtgaa aagagggtaa acataaggag aggcaggctg
    11401 gtcaagacac caagcgaact aacttctacc tccagacctt gcgaaatatt tcccaaaata
    11461 atgggtaaaa cagtaaaagg agttcgcaag gaaacaccaa tcaggataat acctggaaca
    11521 aaaaagagtg attgcttttt catataatac ctcttctagc tgattttaat aacagcttat
    11581 tttaaggctt tttcactata atgtcaagta aggtttctgg ctttcaagat aaaaatggga
    11641 aagtcttgaa aattatgata gaatggtgga aggaaaaatt caggagagta gtagtgactc
    11701 aaaatgttga aagtcttctc gtatccattg taatcagtgc atacaatgaa gaaaaatatc
    11761 tgcctggtct aattgaagac ttaaaaaatc aaacctatcc taaagaggat attgaaattc
    11821 tatttataaa tgctatgtcc acagatggga ccacagctat cattcagcaa tttataaagg
    11881 aagatacaga gtttaactca attagattgt ataacaatcc taagaaaaat caagctagtg
    11941 gttttaacct gggagttaaa cattctgtag gggaccttat tttaaaaatt gatgctcatt
    12001 caaaagttac tgagagtttt gtaatgaaca atgtggctat tattcaacaa ggtgaatttg
    12061 tctgtggggg gcctagaccg acgattgtcg aaggaaaagg aaaatgggca gagaccttgc
    12121 atcttgttga ggaaaatatg tttggcagta gcattgccaa ttatcgaaat agttccgagg
    12181 atagatatgt ttcttctatt tttcatggga tgtataaacg agaggttttc cagaaggttg
    12241 gtttagtaaa tgagcaactt ggccgaactg aagataatga tattcattat agaattcgag
    12301 aacatggtta taaaatccgc tatagcccaa gtattctatc ttatcagtat attcgaccaa
    12361 cattcaagaa aatgctgcat caaaagtatt caaatggttt gtggattggc ttgacaagtc
    12421 atgttcagtt taagtgttta tcattatttc actatgttcc ttgtttattt gttttgagtc
    12481 ttgtgtttag tctagcattg ttaccgatca cattcgtatt cataacttta ctattaggtg
    12541 cctattttct acttttgtca ttactcactt tgctgacttt attaaaacat aaaaatggat
    12601 ttctaattgt gatgcccttt cttttatttt ccattcactt tgcttatggc tttgggacga
    12661 ttgtaggttt aattagagga tttaaatgga agaaggagta caagagaaca ataatttatt
    12721 tggataaaat aagccaaata aatcaaaata tgctataata acaatatagt aaaactcttt
    12781 taaggaggag tagatttcta tgaataaaaa actaacagat tatgtgattg atctggtgga
    12841 aattttaaat aaacaacaaa agcaggtttt ctggggaata tttgatattt tcagtatggt
    12901 ggtttccatc attgtatctt atattttatt ttatgggctg attaatccag cacctgttga
    12961 ctacattatc tatacgagtt tggccttcct gttctatcaa ttgatgattg gtttttgggg
    13021 gttgaacgcg agcattagtc gttacagcaa gattacggat ttcatgaaaa tcttttttgg
    13081 tgtgactgct agcagtgtct tgtcatatag tatctgttat gccttcttgc cactcttctc
    13141 catccgtttc atcattctct ttatcttgtt gagtaccttc ttgattttat tgccacggat
    13201 tacttggcag ttaatctact ccagacgcaa aaaaggtagt ggtgatggag aacaccgtcg
    13261 aaccttcttg attggtgccg gtgatggtgg ggctctcttt atggatagtt accaacatcc
    13321 aaccagtgaa ttagaactgg tcggtatttt ggataaggat tctaagaaaa agggtcaaaa
    13381 acttggtggt attcctgttt tgggctctta tgacaatctg cctgaattag ccaaacgcca
    13441 tcaaatcgag cgtgtcatcg ttgcgattcc gtcgctggat ccgtcagaat atgagcgtat
    13501 cttgcagatg tgtaataagc tgggtgtcaa atgttacaag atgcctaagg ttgaaactgt
    13561 tgttcagggc cttcaccaag caggtactgg cttccaaaaa attgatatta cggacctttt
    13621 gggtcgtcag gaaatccgtc ttgacgaatc gcgtctgggt gcagaactga caggtaagac
    13681 catcttagtc acaggagctg gaggttcaat cggttctgaa atctgtcgtc aagttagtcg
    13741 cttcaatcct gaacgcattg tcttgctcgg tcatggggaa aactcaatct accttgttta
    13801 tcatgaattg attcgtaagt tccaagggat tgattatgta cctgtgattg cggacattca
    13861 agactatgat cgtttgttgc aagtctttga gcagtacaaa cctgctattg tttatcatgc
    13921 ggctgcccac aagcatgttc ctatgatgga gcgcaatcca aaagaagcct tcaaaaacaa
    13981 tatccgtgga acttacaatg ttgctaaggc tgttgatgaa gctaaagtgt ctaagatggt
    14041 tatgatttcg acagataagg cagtcaatcc accaaatgtt atgggagcaa ccaagcgcgt
    14101 ggcggagttg attgtcactg gctttaacca acgtagccaa tcaacctact gtgcagttcg
    14161 ttttgggaat gttcttggta gccgtggtag tgtcattcca gtctttgaac gtcagattgc
    14221 tgaaggtggg cctgtaacgg tgacagactt ccgcatgacc cgttacttta tgaccattcc
    14281 agaagctagc cgtctggtta tccatgctgg tgcttatgcc aaagatgggg aagtctttat
    14341 ccttgatatg ggcaaaccag tcaagattta tgacttggcc aagaagatgg tgcttctaag
    14401 tggccacact gaaagtgaaa ttccaatcgt tgaagttgga atccgcccag gtgaaaaact
    14461 ctacgaagaa ctcttggtat caaccgaact cgttgataat caagttatgg ataagatttt
    14521 cgttggtaag gttaatgtca tgcctttaga atccatcaat caaaagattg gagagttccg
    14581 cactctcagt ggagatgagt tgaagcaagc tattatcgcc tttgctaatc aaacaaccca
    14641 cattgaataa aaaagaaaaa cgcatagtat ccagttacac aaccttggta atatgcgttt
    14701 tattatgtag agacttatac tcttcgaaaa tctcttcaaa ccacgtcaac gtcgccttgc
    14761 cgtatatggt tactgacttc gtcagttcta tccacaacct caaaacagtg ttttgatctg
    14821 acttcgtcag ttctatctgc aacctcaaaa cagtgttttg atctgacttc gtcagttcca
    14881 tccacaacct taaaacagtg ttttgatctg acttcgtcag ttctatctgc aacctcaaaa
    14941 cagtgttttg agcagcccgc agctagtttc ctagtttgct ctttgatttt cattgagtat
    15001 tacttcattt tcttctgaaa tggaattgtt acccagtcta tgctattgaa aatacgccaa
    15061 aacttctaag ggtttgtgag cgatataatc aggttgatag tttagtagat ctgcttgctc
    15121 tccaaatccc caagtgatgg ccaatttctg aatacctgtt tctcgagctc ccagcatatc
    15181 aaacttggta tctccgatga tgatggcttg ttctggtgct agttgatgtg tctgcaaggc
    15241 ttggtgaatg acatctgcct tatggggtgc ttcagggcta gaaccataaa tgccatcaaa
    15301 gaaatgatgg atttccaagt tttttgccat gtcttgagca gtagatgtat cctttgtcgt
    15361 ggtgatgtag agtggataac tgctcgataa ctcctcaagc aagtctataa tctgaggaaa
    15421 gagttgagct tcatagatgc cttttgcctt atagtaagaa cgatatatct gcacggcttc
    15481 agaaatttgg tctttggaca ggcaggtcgc aaaactactt tcgagaggtg gtcccataaa
    15541 accacgaata gttttggcat cagggctagg cacccccagc tctttaaagg tataggtaaa
    15601 ggcattgtga atcccgatag aactatcaac gagggttcca tccaaatcga aaaaaatcgc
    15661 tgtgatagag gtcatggttt ctcctatttg ataagcttat tctccgaaaa tttctttttg
    15721 gaggcgacga ccagtagggg tggtagcgag tccaccttca gctgtttcac gaaaggcagt
    15781 tggcatgctt gctcctactt ggtacatggc atcgatcact tcatccacag ggattttaga
    15841 ttcgatacct gccaaggcca tgtctgctgc gatgaaagca aagctagctc ccatggcatt
    15901 acgtttgaca cagggaactt cgaccaaacc tgcaacaggg tcacagatga ggcctagcat
    15961 atttttaatg acaaaggcaa tagcttgact ggcctgataa ggtgttccac ctgcagccag
    16021 agtcaaggcg gcagcactca tagcagaggc tgaaccaact tcagcttgac acccaccctc
    16081 agcacctgag atggaggcat tgtttgcgat gactagtcca aaggcaccag cagcaaagag
    16141 gaaatccaat tgttgctcgt ggctgaggtc taatttttca atagcagcag tgagaacgga
    16201 tggcagacag ccagcacttc cagcggttgg agtggcacag accaagccca ttttggcatt
    16261 gtgttcattg actgcgatgg catttcgggc agcagagaga atcgtgtaat ctgacagagt
    16321 ttttccgttt tcgatgtagt gatccaattt ggcagcatct ccacctgtca ggccactacg
    16381 agatttattt tcattgaggc caagttggac agaggctttc ataacttcca gattgcgttc
    16441 catgagaagg aagacttctt cacgttcgcg accggtcaat tcaaactctg ttgtaatcat
    16501 gagttctgcg acatttcctt gaaagtctag atctgcttgc tcgaccaatt ctttgataga
    16561 ataaaacatg cttcctccta tttaaagaaa ttgacattgt ggagatgagg gatttttcga
    16621 atttcttcga tagcctcatc acagttgcga ctgtcaactt cgataatcat aatggctttt
    16681 tcaccagctt tttcacgagt gacattcatc tgggcgatat tgataccata gcgggaaagc
    16741 gcctctgtaa caagggcaat catacctgga atatcttgat gaacgatgat gatagtcggt
    16801 gtattcatat tgagagagac ggcaaaacca ttgagttcgg ttacctgaat atttcctcca
    16861 ccgatagaaa taccagtcac gctgatggtc ttgtgggcat ttttaacagt aattttagtg
    16921 gtgttagggt gaggggcatt gctgtctttc tgaatggtcc agacaatctt gataccacgc
    16981 ttgtgggcaa tttccagact atttggaatt tcaggatcat ctgtatccat tcctaaaata
    17041 cctgcaacaa gggctaggtc tgttccgtga ccacgatagg tcttggcaaa tgagttaaaa
    17101 agttggaatt caacttctgt cggagtatca tcaaaaatgg aagagacaat cttcccaata
    17161 cgaacagcac cagcggtatg gctactagat gggccaatca taactggtcc gatgatatca
    17221 aagacagatt gaaaacgaag tgatttcatc agtttcccct tataaaaatt cttatctcta
    17281 ttatatcaaa gaatgagggg cttggcttta attgtggatg aaaacctttc taatacctca
    17341 aatagcataa aaatagtatc ttttatgaca aaaaacacct tatttaggga aataaaaaat
    17401 aattttgtaa tatttctaca taaaagtgtc aagaaacggt aatatttaaa gggtatgata
    17461 gaactataga aagaaggaga attttcgaat atgaaatcaa taactaaaaa gattaaagca
    17521 actcttgcag gagtagctgc cttgtttgca gtatttgctc catcatttgt atctgctcaa
    17581 gaatcatcaa cttacactgt taaagaaggt gatacacttt cagaaatcgc tgaaactcac
    17641 aacacaacag ttgaaaaatt ggcagaaaac aaccacattg ataacattca tttgatttat
    17701 gttgatcaag agttggttat cgatggccct gtagcgcctg ttgcaacacc agcgccagct
    17761 acttatgcgg caccagccgc tcaagatgaa actgtttcag ctccagtagt aagtgaaaca
    17821 gttgtttcaa ctgtaagcgg atctgaagca gaagccaaag aatggatcgc tcaaaaagaa
    17881 tcaggtggta gctatacagc tacaaatgga cgttatatcg gacgttacca attaacagat
    17941 tcatacctga acggtgacta ctcagctgaa aaccaagaac gtgtagcaga tgcctacgtt
    18001 gcaggacgtt acggttcatg gactgctgct aaaaacttct ggcttaacaa tggctggtat
    18061 taagaactaa cgaacaaata atatgtaaaa ggtcgaggag ctccctcgac tttttttata
    18121 atttctttgg ttgataatgg gtctctactt cttttttgag atgagacagc atagaagttt
    18181 cctcggtcag ctccagaagt gagaaacctt tttggataag tttagcatta tctgtacaaa
    18241 tcccaatagg gacatagcag atagcaagcc tatcgtagct tttcttattc ttggcgtcct
    18301 ccagtaaagt gtagcagatt tgcttacaca tgtttttatc ttgattgtat agatagagtg
    18361 tggaaaggtt tagcaggatt gctattcgca agtcatataa atgttgatag tttttataga
    18421 cttctaagcg ttgcaagatt ttctcggatt attgacaaat aaacggacat tctgatagac
    18481 gattgcccta gcggcttagt gtaaacttta caaatttggc ttgtaatttt tttataaaat
    18541 tcacttcagt tacttgacag ttattatatt ttcgcttatt atatagataa aaggatggga
    18601 taggagttta aaaatttgaa agcgctatcc ataatcataa cgcataattg tctccttttc
    18661 gtgaaaaaag ttaacgtaat tttgaaatga gcttaataag aggtatgatg taggtagaaa
    18721 ataaagatag gagaaaaagt atgaataaaa aaatattttg tattctagta tgtattatat
    18781 cattgattag tctagctata atctttccat ggggctggtc gatataatgt aagggagctt
    18841 gagttgttag tggaggataa aatgttaaga gtaatagtag ttattcaatc tttagtaata
    18901 atactgcttg ctgttgcttt attattatct cggaaaaact ttgattcgtt aaatgttgtt
    18961 cttataatga tgatcgtatc acaattgttg ttattagtat atttgataaa atcagggaat
    19021 cagtgattag ctgttatttg aattaagtaa actgttaagc ttcaagcagt aactggtttt
    19081 aaatatttaa aataagataa aggaaggaag tctaatttag gtaactaaac aaagcctgcg
    19141 atcacttgtt aggaaaccat cctaagcatg cttaataaaa aaggagaaaa taaatggaac
    19201 ttgtattacc aaataattat gttgtgattg atgaagaaga gatgatgtac cttgatgggg
    19261 gggctatata tatacccagg tgggcaatta caggagccat tactggtgca gcatatgcag
    19321 cattagcagc agcaggaggt ggaggccttc aactagttct tgcatcttat ggattacgct
    19381 ccgcactggt agctgggatt gttaaaggtt taggagtatt aggaattcat attggaaatg
    19441 cttttgcaaa tactgttatt agaagtattg catctgctgg aattggtgct ggagctgatt
    19501 ggatttttac caatattatt gatggctggg atgggcgacg tgataatcaa ttgagaatag
    19561 gttaataatc ttatgttgat tgttttaatt tcagttattg ttgcattcct gtatcataaa
    19621 attacagagt atgtcaacaa caggaaaatt gatattgtta tttttctatc attgctgatt
    19681 tctcatttta tttggaatta ctatttttta ccaattgaaa tattgatagc aatcagtgga
    19741 gcaaatttat tattaagttt tttaaaaaaa ttacagatta aataatatta ttccatatga
    19801 catatcaact aggtcattag attttattga agatataaat taaaaacgag gttgggaaaa
    19861 aactcaattt gaaagtgaga ttgagtaaat ctttctatct atataacgta tatcatcaat
    19921 atttttgaac acctgataat atgcactttt cttattttaa agattttttg cctttattca
    19981 tttcttgaat gaattggaga gatgacttta tttaggtgtt tgacattact atagatagga
    20041 tttagcagta ctaatatgaa ctcatattat aggtgtagac ttaaattttg gaagcaagct
    20101 aaaggatatc ttatctaggt aactaagtgc tataacaaga tatattggtg gagttagtat
    20161 ggcaactatt actaatgctc ttaatattgt ggctactgtt gctgaagtct tctcattagg
    20221 aggagccatt gcatatggtt tagatatcgt agacggtaaa tttgatgggt atttatgggc
    20281 gtaaaactat agctatgaaa catttttttg caggaattgg tgaaattcat tttttgttat
    20341 ttttattata tctaagcatg tctgctagtc caattattgg actagtgatt ggatatacta
    20401 aaataaatct aataaattct attattatag ctcttggtat gatattggca ttaattttgg
    20461 tattatcaag agtgtataga aaatattttt atagagacga tgatgactaa agtttttatc
    20521 aataatttgg gctccttgtc aactgtagtg ggttgaataa aagctaacgt ctggggaagg
    20581 gtttaaagct ttgctttatc aaatattgac ttacagagtt gctctattgt attgatgcat
    20641 tcttagtaaa taatatggtg ttttaaatga aagatgatca gaaatattta ttagcgggac
    20701 tttattcgct tctagttgca atattttatt ttccattgat tgattccaag gggatttttg
    20761 taagtatatt gatggcggtt ttacttttat atttaatata cttcattgca acagtcattc
    20821 atattgtgat aattaagttt ataagaaaaa aatcttttaa gtatttggtt ctatatccat
    20881 ttacttatga tgggagctgg agatttcaac ctataaactt actctacttt ccagaaatgg
    20941 tgagagatgt cattccgatt aatttagttc aagaatattg ccaaggacaa ccttacggac
    21001 tgttaaaaaa gatgctgaaa agaattcgat tgtcacgaga gatatcttta ctcctggcta
    21061 ccattatcgt ctattttttt acgcatagaa ttctacctct ttcagtattt acgttcatat
    21121 tttcttacat attgctattt gcacaatctt atttgggtgg taataccgct tggattggaa
    21181 atagaagatt aataatagat gatgaatttg aaaaaatctt gctttcaaaa agttatataa
    21241 aagaaatatc atctgcacga tactcagaat acttgacatg tgaatacaaa aactttacac
    21301 caatcatatt gttagctatt tttgaaaatt tgcttgactc ctacttgctt cagaatcaga
    21361 gtgaggttga cttagatatt ttttataaag ttttaccttt gctttataaa gaaaaatata
    21421 ctatgggatt caattacttt gtaagtttaa attatttact atataaggtt ggatttttgg
    21481 gaatcattta cgataatgaa gcattaagag atttgtcaaa acaatattta aacaaaaata
    21541 tttcggaatt acaagatggt tctttcgagg acggtataca agatgctgtt gcctctaaac
    21601 aaatagtagt tataaatgaa tttatagctt gtttaaattc cagatgcgtg ccatcccaat
    21661 atgatagatt tttttataaa gatagacctt atattttttc cagaaagagt cctattaagg
    21721 ggtgaaaatt tgttacattt ggattaacaa gtgtcctagg gattagaaat aactctagta
    21781 tagctagata tttttgagta actagaaata tcattagtct acccatatga ttgccagaaa
    21841 agatggctga tgaatcttat ttatactgtt gcagtaggcg ttgtctagga taaataagct
    21901 atcttgatgg gggagattgg aataatttta gtagaaacat taaaggatta tggacaagta
    21961 gcgcaggatt aggtgatgca atgtgctaag ttggcttggt gttagcagta gtattattta
    22021 acaatggaaa gtagactaat gaaaaataag cgttattttt ttgacacaat tttaataatt
    22081 ttactgctta taagcacgat attttgtgtc agcccagtat ttataaaatt ggacatctta
    22141 ggaactccct ctcatgccat cttaaccttt gtattggcga taccgttatt ctatattttg
    22201 tctcaatgct tacatacttt gctattacta gtttcctcaa tcttttgtaa attaagacca
    22261 atttattttt attttatatt tgtgatcatt ataggagcta ggaaatacta tcgaattctc
    22321 tttcaccaac taatgggatt tagtccagga atagcagtgt tttataagga gagtcaaaca
    22381 actaagaatc tgtttaaatt ttactacttc ttgtacttta caacactaat ttcatactat
    22441 tttttcttta cttttgtgta tgacaaatcg ttgcttttgc ctcttattcc attttctatt
    22501 atcatagcat tagtacaaaa actttataga attgagaatc aacaattatt tctgttaaaa
    22561 tcaaaagtac taacaatact ggaatctaag agggattgtg agtttaatct tcaggattat
    22621 catgaaattt ggaaattgca atcaaaatct gagttgccat gcgtggcttt atcttatatc
    22681 agtttgatca agccatatct ttcagagagt gtgcgtgaac aaattgattt attagaagtt
    22741 aagcgattta aaaaaataaa tcatccaata tcactttatg gtatgttgga tgttataaaa
    22801 ttaaatctat atttacggca ttataatgaa aaaaataaat atgaatcaat gttaaagaaa
    22861 attttagagg taagaccaga ctttgtttta atcgagcaga atattgatga tagtttaaat
    22921 agctcgcaac ccttatcttt atctttagcc atttcagaaa tccaactttt gcttgaagtg
    22981 tatatgggga tcaaacatgt ttcaattagg agataaaacc agaataatat ttgccattat
    23041 aggggcaagt tgcatattag tcagtatgta tcttattcca cttattaaaa ctgagaataa
    23101 attttgggaa atacttttat ttatattagg tgtattgcta attggaattg cgttactaag
    23161 tcaaaaaaaa taaattttga aatagtatta gtgagttcgc aattatttat tgctagtggt
    23221 ttagaactgt taagtttcaa acaataattg attttaaacc ttaggtaacc tataaaaaca
    23281 aataaggtag agaaaggata tcttatatag gtagctaagt gataaaaaca cagtcgtcta
    23341 tcacttgtta ggaaactatc ctaactatgc ttaataaaaa aggagaaaat aaatggaact
    23401 cgtattacca aataattatg ttgctcttga gcaagaagag atgatgtatc ttgatggggg
    23461 attttctatt ctgagatggc ctgttgcaac agccattaat atagctttta atggtgtttt
    23521 aggtggagga gcaatcagtc tagttagaaa ttatattcgt aattatggtt tgcggcgagt
    23581 tacaagcgca attgctggag cagctgcaag atatgttggg gtacgagttg caaatagagt
    23641 ggcaggattt gcactgtctg ctattaatgg atttgcagct tggatgtcaa ttggcgatgc
    23701 tattacaaca atctgggcca acaatgatgt aaataggaga gacccaaatt taaacgcctt
    23761 gtggtaacta gatatgggta ttaaaatgga aaaaattttt gttattattt tttttgtatg
    23821 tctatttata tcatccataa cttttttagc ctatgatttt gttagcgaag aaataaaaaa
    23881 attgattatt tggatgaatg tcgttttttt gattttaatc atagcaatga taatttatcc
    23941 aaaattaaga aaatgataag gacactgtaa aattatgata cgtaaactaa tcattttttt
    24001 attaatgctc cctctttttg tcttgtggct agagttgcat gtcctagtga ataacttact
    24061 attgaatcta gaatctcccc ttgattttgt gattagtatg agtcttgctt tctgtagttt
    24121 gattttatca aaaatagttt tagacatact atacgcattg aaagatttgt acaagaaaga
    24181 agctcttatt acgatttttc cttttatttt tataggcagg aagaaagtaa atgtgaggtt
    24241 ctcgccctat ttttcattcc atcgtaaaag tttgtcgcct gatgatttaa gatctaggat
    24301 tatatggagt tttattcttg aaattgctat tatcctagta tttattttaa aaattccttt
    24361 tgcaatcatc atgcttacta caatattttt ctggactata atggatatca atcatctcgt
    24421 ttttaataag acggaatttc ttttcaatca aaataaatgg gaaaaagaag attcgtttga
    24481 aagtgatttg acaaatacgt taaaggataa aatacaaaaa tcagatctca gttattctga
    24541 cttaatgtct cttcagctgt atgatgcgat gaatcaatct acctttttaa cggatagtga
    24601 actctttgag gatattctga gtaaaattga agattctcat aacacccttc tgtgtacagg
    24661 tcttgtcgag ttactgctgt atgagatttc tattagtaac aataacaact ggtccaacaa
    24721 ggttgataaa attaggatac acctcatcag aatcaatcaa ttagattttt tctattatac
    24781 aagttggtta aggcaaaatt ttgatttctg tatgaataga gagtatcata aaatgaaatc
    24841 tcggaaatta ttactgagta ataaaaagat agtttaagtt cgtcctattt gtaaaacaaa
    24901 tgaaacaatt tcaactaagg aggagaaaac aaatggaact tgtattacca aataattatg
    24961 ttgtgattga tgaagaagaa atgatgtatc ttgatggggg ggcttattta agcaagagtg
    25021 attgtcaagg aatttgtgca gctttagcta tgagcccagg aacttttata gcattagctg
    25081 gatctgcagt tttaactaaa aaactaataa actatattaa gtttggaggt cttggaggct
    25141 ggcttattgg tgcagcagca ggtgtattgg ctacagcagc aggaaaaata gcttactgta
    25201 ttggatatgg tgctcttaat agaggttgtg atattagcgg gaacccttat ccttgggatg
    25261 gattcatatc tgcgacagta agatgaataa tgtagataag attcgaaaaa tacatattat
    25321 cgtatgttgg atgtatatat ttttatcatt cagggcgatt ataaatgaca cggagtattt
    25381 tttgcttatt tttttagctt ttatctactc aatagtatca ctacctctat attctgtgaa
    25441 aaataaaata gtatctatct gtctagccat aaattcgatt ctgttaatga gtttccccat
    25501 tttaatcaat aagtttttcc cagaaagttt tttgacttat accgtattaa taagtgtttt
    25561 tatcctagag ttagcaatct ttcatttaat tggggaagat tttgctacta aattgactaa
    25621 cgaatataag aaaattagtc agtttagaag caaggtgtct caatctcctt ggataaaata
    25681 tttagagatt tctagtttta tattaactat atttccatct attctttacg gtacagttga
    25741 taatcgtgta ttggctctta tctttttgat aaaaatttgt gtagatacta cgataaaatt
    25801 tttattcatc agattatttg acacaagtac tttaatgaag aggagaatat tttttctttt
    25861 cgcattggat gttatagctt acttattttt aggatatctt ttagtgattc aaaaagcagg
    25921 ctatttgttt tcggttttac ttcttttttc taatttttca gttccattta tcaaagcaaa
    25981 ggaatacgaa ttatttaaaa atagcaagta atagaaacat aggttaaatc ttagaacggc
    26041 ttaaaatcag atatgataaa gggaaatagt cttatctagg taactaagtg ctacaaacac
    26101 agtcgaggat cacttgttag gattacattt taatcatgct taataagaat ggagaattcc
    26161 tatggggatt gtattactct gaagtttcga ataccttagt tctcgtgatt ttgagctgtt
    26221 ctagctttag aatccttcag aatgtaaaat tttaagcagt caaagactta gaatagcctg
    26281 gaaacattta ttttatagca attctaggct tagaattgct catatatatg tatttgagct
    26341 gctcgatagt taggacagct ctattctgag aaatctgagc tatcaatgct tcagaatagt
    26401 atttcgcaaa tggtttttat tgaagaggtg attgttttat gatagtctaa aataaaactg
    26461 atttaatgga gtaaatggag aatcgtcaca tgaaacattt ttttgcagga attggtgaga
    26521 taaaacttgt tggctactta ttgtatatat gtgtaggact agcccctctt tttcatatat
    26581 atgtcatagg ttcggaactg agttttgtga aaatagtgtt atctattttg ggagttatat
    26641 ttgtaagtat gttaactatt gctcgaattt atcggacttt tctataaaga atagtttgga
    26701 cttgaactgt atctaaaaac agaggttggt cgattatcag cctctttctt gtcgttgaaa
    26761 agagtgagat atattgactt ttgaaaaaaa tgtcataatt gagttgggat aaacctaaaa
    26821 gtaatatagt agattgaatc tggaatagtc cgttatgact gttaaaatat ttctagaaat
    26881 taatttgact ttcctaatcg atttgttcac atcttgtttc aatctactat actttctcgt
    26941 taaaccgttc ggcaattcat ggtgacatgg acacatagta gtaagcacat tatgtggctt
    27001 ggcagagcta aaaactgttc ccttgcgata agcctaataa gcacaacata gggagttaga
    27061 gaagccgact ctaatcaacc actttgggca gtagtgagaa ctgccccgtg ctttttattt
    27121 tgagaaaata tggagtttgt cgttgaaatt acttgattgt attttggact atcaagaaag
    27181 attcaatgga aaaacatgtc aagtatcaac gaattataag tatttagaga ctttcaaagt
    27241 gaatttttgc ttgactgatt tacatcattt atttggctta cacaaaatca cacgagatta
    27301 tgctagtcaa acaaaacctg ctattcaaga tggtgttttt attttagaag attttagaaa
    27361 tatcctattg tacaatgatg taatcgaaag gatatcttta tatgagttta taggtgatat
    27421 tttctattct aaaataacaa gttgttgcat cgtagctaag gatttatcta aaaatactat
    27481 gaaattggac gtcatatttt ttgaggataa aaataaaaga tccgcagttt taggtttacg
    27541 aagagacaaa agcggagtat ttaaaccagt taccctacat tttacaagcg ctaagaaata
    27601 tgctaaagtt cgtaaaacag atgtgaaaga aatgaaatgg ctataaagat tgtccgcagg
    27661 cttaagcttg cgttttttgt tgtttaacga aattaaaaaa acaagctctc tcatcggaaa
    27721 tgtttttata ggaatgaagg aagatgatgc tatgtttaaa aagagaatcg aaaagggcaa
    27781 aagtagtgtc tttatctttt tggagtagaa gcttatgata tagaaatttg taataaaaat
    27841 gtaatataaa acatttgaca aatatttacg gggggagtat acttaatata agtatagtct
    27901 aaaaatgact atcagaaaag aggtaaattt agatgaataa gaaaaaaatg attttaacaa
    27961 gtctagccag cgtcgctatc ttaggggctg gttttgttac gtctcagcct actttggtga
    28021 gagcagaaga agctcccgta gctaaccagt ctaaagctga gaaagactat gatgcagcag
    28081 tgaaaaaatc tgaagctgct aagaaagatt acgaaacggc taaaaagaaa gcagaagacg
    28141 ctcagaagaa atatgatgag gatcagaaga aaactgagga gaaagcagag cttgttcgaa
    28201 aagcggatga aaaacgtcaa aaagcgaatt tggcagttca agaagcatat gtaaaattcc
    28261 aagaagcaca aagagaattt aacgaaagtc caagcagaaa aaaatctgat gctaaaaaga
    28321 aattagatga tgcatcagct catattgaag aggtaaaatt aaaacaaaaa gaggcggatg
    28381 cgaattttaa taaggaacaa gcaaaagtaa ttcccgaagc aagtgactta gctgttacta
    28441 aacaaaaagc ggaagaagct aaaaaagaag cagaagtagc taaggaaaaa tatgataagg
    28501 cagttcaaga ggtagaagta gagaaaaata aaatacttga acaagatgct gaaaacgaaa
    28561 agaaaattga cgtacttcaa aacaaagtcg ctgatttaga aaaaggaatt gctccttatc
    28621 aaaacaaagt cgctgaatta aataaagaaa ttgctagact tcaaagcgat ttaaaagatg
    28681 ctgaagaaaa taatgtagaa gactatatta aagaaggttt agagcaagct atcgctgata
    28741 aaaaagctga attagctaca actcaacaaa acatagataa aactcaaaaa gatttagagg
    28801 atgctgaatt agaacttgaa aaagtattag ctacattaga ccctgaaggt aaaactcaag
    28861 atgaattaga taaagaagct gcagaagatg ctaatattga agctcttcaa aacaaagttg
    28921 ctgatctaga aaacaaggtt gctgaattag ataaagaagt tactagactt caaagcgatt
    28981 taaaagatgc tgaagaaaac aatgtagaag actacgttaa agaaggctta gataaagctc
    29041 ttactgataa aaaagttgaa ttaaataata ctcaaaaagc attagatact gctcaaaaag
    29101 cattagatac tgctcttaat gaattaggtc ctgacggtga tgaagaagaa actccagctc
    29161 cagcaccaaa accagagcaa ccagctgaac aaccaaaacc agcgccggct cctcaaccag
    29221 ctccagcacc aaaaccagaa aaaacagatg atcaacaagc tgaagaagac tatgctcgta
    29281 gatcagaaga agaatataac cgcttgcccc aacagcaacc gccaaaagca gaaaaaccag
    29341 ctccagcacc aaaaccagag caaccagttc ctgcaccaaa aacaggttgg aaacaagaaa
    29401 acggtatgtg gtacttctac aatactgatg gttcaatggc tacaggttgg ctccaaaaca
    29461 acggttcatg gtattacctc aacagcaatg gcgctatggc tacaggatgg ctccaataca
    29521 atggttcatg gtattacctc aacgctaacg gcgctatggc tacaggttgg gctaaagtca
    29581 acggttcatg gtactacctc aacgctaatg gtgctatggc tacaggttgg ctccaataca
    29641 acgattcatg gtattaccta aacgctaacg gcgctatggc tacaggatgg ctccaataca
    29701 acggttcatg gtactacctc aacgctaacg gtgctatggc tacaggttgg gctaaagtca
    29761 acggttcatg gtactacctc aacgctaatg gtgctatggc tacaggttgg ctccaataca
    29821 acggttcatg gtactacctc aacgctaacg gtgctatggc tacaggttgg gctaaagtca
    29881 acggttcatg gtactacctc aacgctaacg gttcaatggc
//
LOCUS       DAYYYC010000024        28752 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.024, whole genome shotgun sequence.
ACCESSION   DAYYYC010000024 DAYYYC010000000
VERSION     DAYYYC010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.024"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            1..1098
                     /gene="ald"
                     /locus_tag="ACHBV5_001134"
                     /pseudo
     CDS             1..1098
                     /gene="ald"
                     /locus_tag="ACHBV5_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(1399..1725)
                     /locus_tag="ACHBV5_001135"
                     /pseudo
     CDS             complement(1399..1725)
                     /locus_tag="ACHBV5_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(1728..2228)
                     /locus_tag="ACHBV5_001136"
     CDS             complement(1728..2228)
                     /locus_tag="ACHBV5_001136"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9966940.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVIDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            complement(2421..3389)
                     /locus_tag="ACHBV5_001137"
     CDS             complement(2421..3389)
                     /locus_tag="ACHBV5_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFM9966941.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(3475..3690)
                     /locus_tag="ACHBV5_001138"
     CDS             complement(3475..3690)
                     /locus_tag="ACHBV5_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFM9966942.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(3699..4553)
                     /gene="cvfB"
                     /locus_tag="ACHBV5_001139"
     CDS             complement(3699..4553)
                     /gene="cvfB"
                     /locus_tag="ACHBV5_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HFM9966943.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGCVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(4613..5170)
                     /gene="frr"
                     /locus_tag="ACHBV5_001140"
     CDS             complement(4613..5170)
                     /gene="frr"
                     /locus_tag="ACHBV5_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFM9966944.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(5179..5916)
                     /gene="pyrH"
                     /locus_tag="ACHBV5_001141"
     CDS             complement(5179..5916)
                     /gene="pyrH"
                     /locus_tag="ACHBV5_001141"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFM9966945.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(6000..7334)
                     /gene="trmFO"
                     /locus_tag="ACHBV5_001142"
     CDS             complement(6000..7334)
                     /gene="trmFO"
                     /locus_tag="ACHBV5_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HFM9966946.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(7629..7901)
                     /locus_tag="ACHBV5_001143"
     CDS             complement(7629..7901)
                     /locus_tag="ACHBV5_001143"
                     /inference="COORDINATES: protein motif:HMM:NF036719.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFM9966947.1"
                     /translation="MFTCFIIHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSG
                     KIKYHEDSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            7878..8682
                     /locus_tag="ACHBV5_001144"
     CDS             join(7878..8246,8248..8682)
                     /locus_tag="ACHBV5_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HFM9966948.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRPKKQLANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     CRDMKLFKMSRRNIGQAGKILSDSGYQGLMKIYPQVQTPRKSSKLKPLTAEDKACNHA
                     LSKERSKIENIFAKVKTFKMFSTIYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(8674..9317)
                     /locus_tag="ACHBV5_001145"
                     /pseudo
     CDS             complement(8674..9317)
                     /locus_tag="ACHBV5_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(9426..9944)
                     /locus_tag="ACHBV5_001146"
     CDS             complement(9426..9944)
                     /locus_tag="ACHBV5_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HFM9966949.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(9981..10109)
                     /locus_tag="ACHBV5_001147"
                     /pseudo
     CDS             complement(9981..10109)
                     /locus_tag="ACHBV5_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            complement(10171..11040)
                     /gene="rsmI"
                     /locus_tag="ACHBV5_001148"
     CDS             complement(10171..11040)
                     /gene="rsmI"
                     /locus_tag="ACHBV5_001148"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFM9966950.1"
                     /translation="MQIQKSFKVQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(11043..11360)
                     /gene="yabA"
                     /locus_tag="ACHBV5_001149"
     CDS             complement(11043..11360)
                     /gene="yabA"
                     /locus_tag="ACHBV5_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFM9966951.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(11400..12290)
                     /locus_tag="ACHBV5_001150"
     CDS             complement(11400..12290)
                     /locus_tag="ACHBV5_001150"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFM9966952.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(12287..12925)
                     /gene="tmk"
                     /locus_tag="ACHBV5_001151"
     CDS             complement(12287..12925)
                     /gene="tmk"
                     /locus_tag="ACHBV5_001151"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFM9966953.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLELHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMDLAK"
     gene            complement(13145..13942)
                     /gene="proC"
                     /locus_tag="ACHBV5_001152"
     CDS             complement(13145..13942)
                     /gene="proC"
                     /locus_tag="ACHBV5_001152"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFM9966954.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFYQLLAKAGLLVELGES
                     LIDAATGLAGCGPAFVYLFIEALADAGVQTGLPREIALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(13946..15208)
                     /locus_tag="ACHBV5_001153"
     CDS             complement(13946..15208)
                     /locus_tag="ACHBV5_001153"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFM9966955.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAIGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(15218..16327)
                     /gene="proB"
                     /locus_tag="ACHBV5_001154"
     CDS             complement(15218..16327)
                     /gene="proB"
                     /locus_tag="ACHBV5_001154"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFM9966956.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQ
                     ADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(16428..18311)
                     /gene="cbpE"
                     /locus_tag="ACHBV5_001155"
                     /gene_synonym="pce"
     CDS             complement(16428..18311)
                     /gene="cbpE"
                     /locus_tag="ACHBV5_001155"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HFM9966957.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(18314..19201)
                     /locus_tag="ACHBV5_001156"
     CDS             complement(18314..19201)
                     /locus_tag="ACHBV5_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFM9966958.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(19191..19652)
                     /gene="lspA"
                     /locus_tag="ACHBV5_001157"
     CDS             complement(19191..19652)
                     /gene="lspA"
                     /locus_tag="ACHBV5_001157"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFM9966959.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(19649..20557)
                     /locus_tag="ACHBV5_001158"
     CDS             complement(19649..20557)
                     /locus_tag="ACHBV5_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFM9966960.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            20586..20747
                     /locus_tag="ACHBV5_001159"
     CDS             20586..20747
                     /locus_tag="ACHBV5_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFM9966961.1"
                     /translation="MIPYFRSFPKRKKEHPILLNYLHYLPFSRQSYFQNQFKKISGYT
                     PLQYRKEKR"
     gene            complement(20799..21470)
                     /locus_tag="ACHBV5_001160"
     CDS             complement(20799..21470)
                     /locus_tag="ACHBV5_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HFM9966962.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(21524..21745)
                     /locus_tag="ACHBV5_001161"
     CDS             complement(21524..21745)
                     /locus_tag="ACHBV5_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HFM9966963.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            22017..22826
                     /locus_tag="ACHBV5_001162"
     CDS             22017..22826
                     /locus_tag="ACHBV5_001162"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFM9966964.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(23007..23882)
                     /gene="aguB"
                     /locus_tag="ACHBV5_001163"
     CDS             complement(23007..23882)
                     /gene="aguB"
                     /locus_tag="ACHBV5_001163"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HFM9966965.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(23892..24977)
                     /gene="aguA"
                     /locus_tag="ACHBV5_001164"
     CDS             complement(23892..24977)
                     /gene="aguA"
                     /locus_tag="ACHBV5_001164"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HFM9966966.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(24974..26101)
                     /gene="nspC"
                     /locus_tag="ACHBV5_001165"
     CDS             complement(24974..26101)
                     /gene="nspC"
                     /locus_tag="ACHBV5_001165"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HFM9966967.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(26101..27360)
                     /locus_tag="ACHBV5_001166"
     CDS             complement(26101..27360)
                     /locus_tag="ACHBV5_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HFM9966968.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(27357..28217)
                     /gene="speE"
                     /locus_tag="ACHBV5_001167"
     CDS             complement(27357..28217)
                     /gene="speE"
                     /locus_tag="ACHBV5_001167"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HFM9966969.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            28472..>28752
                     /locus_tag="ACHBV5_001168"
     CDS             28472..>28752
                     /locus_tag="ACHBV5_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM9966970.1"
                     /translation="MLYVGIDIAKNKHDVTALNVQGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALEDTGHYAFNLLNFLHEQGYKVYTYNPLLIKEFAKSLSL"
BASE COUNT         8281 a         6599 c         5275 g         8597 t
ORIGIN      
        1 cccaaaagaa attaaaaata acgaaaactg tgtcgccctc acacctgcag gtgttcatag
       61 cttagttagt cgtggtcatc gtgtccttat cgaaacaaat gctggtctcg gttctggctt
      121 tactgatgct gactatcaaa agcaaggagc tgagattgtc gctactgctg gtgaagcttg
      181 ggcagcagag ttggttgtga aagtaaaaga acctttaagt tctgaatacg gttacttgcg
      241 cgacgttctt cttctcttca cctacttgca catggccgct gctccagaat tagcagatgc
      301 tatgttagca gcaaaaataa caggaattgc ctatgaaact gttcgtgaca atcaaggaca
      361 actaccgctc ctcgttccta tgagtgaggt tgcaggtcgt atggctgttt aaatcggagc
      421 tcacttcctt actaagcaag ctggtggctc tggtgttcta cctggtggtg taccaggtgt
      481 tccaaaagga aaagtaacta tcatcggtgg tggtgtcgtc ggtacacatg ctgcccgcat
      541 cgcccttggt cttggtgctc aagtgactat tttagatatt agtgccaagc gtctctcagt
      601 tctagaagaa gtctttggaa gtcaaattca aactcttata tctaattcat tcaacattga
      661 agcaagtatg agagatgctg atgtggtgat tggagccatt ctcatccctg gtgcaaaagc
      721 accggaattg gtgacagatg agatggtcaa acaaatgcgt ccaggctctg tatcgttgac
      781 gttgctgttg accaaggtgg cgttatcgaa acagctgacc gtgtgacaac gcacgatgaa
      841 cccgtctatg aaaaacacgg tgttctccac tatgccgttg ccaatatccc tggtgcggtt
      901 gctcgcactt caaccatcgc cctaaccaat gtcactcttc cttatatcga agctttggct
      961 ggcaaaggat tcgcacaagc aatctctgaa gatgaaggct tgcgtcaagg tgtgaccact
     1021 tatcaaggtt acttgactag cctaccagtt gctcaaggac ttaatcgtga ctacactgat
     1081 atcaatgatt tagtataaat tttgaaaaga aaagggtgac ttcgcaagtc ctacccactg
     1141 tgctttgtgt catcagctat tacatcgttg gtttattgta ctgtatactt tgcaactgga
     1201 gactttcgtt ccagactcaa ttgtgcataa gaaactctaa attgaataaa gtcaacagag
     1261 tttcgcccaa ccacttcgtc ttgtaatgac aattatataa accaaaggaa gctgagctct
     1321 ttagtcccag cttcttttta tatataaaat tttacccgtg caaagacagg gccttagcag
     1381 acttcttttt tacttcgttc acccttgctt tttcttttta ggtttgggcg ttggcagttg
     1441 gttatacata gctaaaatca ggtcttatag aaacatctta ttatcaagtt cttccactca
     1501 aatcatttct ttggcacctt tgtatggaaa ctcaaaaaaa gattggtcaa tcttatctaa
     1561 gactgcttgc acgggtttaa ctaaaaagcg atcatcataa atgccgccaa taatcttgcc
     1621 gcggaagtaa agaatatact cccccatcat ggaacggtaa gtcacatcat ctaatcctga
     1681 taattgttcc aaaacaaatt ccaaatagtt cttacttgat gccatttcta atcttctagg
     1741 ctctgttcag cgataacaac cgtatagagt tcttgcttaa cctcgcatcc aattgattta
     1801 aagccctgct tttcccaaaa atgctgagat tgcggatttc ccttaacata agccaaacgt
     1861 gcctttcgaa agttcttagc aaaataagct agtgcttctg tcacaatatg actaccaatc
     1921 cctttcctct gataggcttg atcaaccata aacaaaccaa taaaaacagt ctcctcatca
     1981 ggatgtgcat agacaaaatc tataacagcc acaaggtcag atccattcca aaatccaaca
     2041 aaaaacttat cagccttagc tttaccttca ggtagacaaa gcatgtcctc ttttacagtt
     2101 gcaaaatttg gctctggtgg acaatgctga aaatacagag gattactttc atataaagat
     2161 aaaatacttg gaatatcctt ttcagttagt atcctacaac tgtaatactt agatagttgg
     2221 tcaatcatct tttcaaattc ctactttctt gtgccctgtg attatgacac aggaagatgc
     2281 actgatcgtc atcagccaca taaaagttct ttccatcgtg cctaatcgtt gtctcaaacc
     2341 tttggataaa acctttagcc tatacaactg gattttcctc tctcaaaagt atattctttt
     2401 gcaggcaaac ttcctcaaaa tcagtcgtgt gcaacttcag tagaatattc ataggctcgg
     2461 ataatctgag cgacaactgg atggcgaacc acatccttgg ctgaaaaatg aacaaagtca
     2521 atctgatgga tgttcttgag tttctcttga gcatcaatca aaccggactt gacattacgt
     2581 ggcaggtcaa tctgactaat atctccattg acaatcatct tagaatgaaa acctaaacga
     2641 gtcaagaaca tcttcatctg catgatggtc gtattttgcg cctcatcgag aatgacaaag
     2701 gcatcatcca aggtccgtcc acgcatatag gcaaggggcg caatctcgat aatttcacgc
     2761 tccatgagtc gagttgtttg gtctttcccc agaatctgat acaaggcatc gtaaacagga
     2821 cgaaggtaag gatccacctt ctccttaaga tcacccggaa gaaatccaag actctctccc
     2881 gcttccaccg ctggacgagt taggataatt cgcttgactt gcccacgttt aagggcagtc
     2941 actgccaagg tcactgcaag gaaggtcttc cctgtacctg ctggcccaat tccaaaggtc
     3001 acatcatgct gtttgacact gtccacataa agcttttgcc ctagggtttt gacacggata
     3061 ggtttcccag tattatcttt gataatttct tcttcgtaaa gggcgacaaa cttgtcaatt
     3121 tcatcatttt tgaccatgct aatcgcagtg actacatctg gcgtaccaac ggtcatccca
     3181 cgatttacca agaccatcaa agcctgaata acttgacggg cttcctcaca ggcagactct
     3241 tctcccaaaa cctggacaat ctccgtacga gcatgaatca caacatcaag ctcttcttcc
     3301 atcaaacgaa gatggcgttc attggaacca aaaagatgaa acaggtcatc tggatgactc
     3361 agttgaatgt ctattgaatg ttccttcaaa taaagaacct ctctaatcct tttatttctt
     3421 tttattatag cagagggatg gagaaattac tagcccaaac ccaatgaata aatgctagtg
     3481 ttctagatat tcctgccaaa tgctgtcaaa atctcctagg ttaaaagaga aactggcatg
     3541 ctcctccaaa aagcgactga cctcatcaaa atcatctgta tgttttggaa aagctgcctc
     3601 ttcaaaagcg aggtctgcca aaattgcttt gggactgtta cttttaggat tgcgctcggt
     3661 catgagccaa gtgtaaaatg attttctcat aagcctccct aaatcaactc tgtcccaaac
     3721 tggtcctgct tgattttacc agccttcata agaccaccta aagctttctt gaactgacct
     3781 ttagaaatgc caaaggttgc cttgatgtcg tctggagatg acttatcatt taaggtcatg
     3841 aaaccgccat tactttccaa ataagtcaaa atcatctgag catcgttttc caacatttca
     3901 aaggagcgtg gtttgaggga gaggttcaga gtgcggtcca cttcacggaa accaataacg
     3961 cgcgcatcta atacttgccc caaacgtggc tctgcgtaac gctcgctagg atgaataaaa
     4021 ccaagcatat tattttctgg taggtaaaca aaagttcctg acagcttgag acggtaaaca
     4081 atggctggcc agttttggtt ctgcatgttg ttgtaggcag gacgagcaag acgttggaag
     4141 tcttcttgat aagccaagag gccccagata cggtctttct tatccacttc aagacggatg
     4201 tagagttggt cgcccttctt aggccagagt tccttgagct cagggagaat atcgagtgac
     4261 acaacgattt ccttgtcagg aaggcctgta tctacaaaga cacccaagtc cttacgaacc
     4321 tctgtgacac atccccaacc aaattggtcc tgagtggcag tcacttctaa ggttgtcagg
     4381 cggagttttt gcttcatatc cgtgtatgca aaacctttga ccgtatcccc tactgtatgt
     4441 tggccctctt ccttagcaag agcataggtt tgaccatcct tttgcacaaa gtaaaaacgg
     4501 tcattttcat cgatgatcag tccaacgata aaacttgcaa gatttgtatt catatttcct
     4561 tctttcgaat aaaactcagc cagcaatgcc aactgagttt ttctgtttat ttttagactt
     4621 ccaaaagttc tttctctttg ttagcagtca tgtcgtcgat gtgtttaaca gcatcgtctg
     4681 ttactttttg aatatctttt tcaagagtct tcaattcgtc ttcagtgatt tcttttgctt
     4741 tttcttgttt cttagcttcg tccatagcat cgcgacggat attgcggaca gccactttag
     4801 cattttcgcc gaccttcttc acttctttag caaggtcacg acgagtttct tctgtaagag
     4861 ctgggataac caagcgaatc acagaaccgt cattagccgg tgtgatacca agatcagaag
     4921 cgttcaaggc acgttcgatg tctttcaatg aagacttgtc aaatggtgtt accaacaaaa
     4981 cacgcgcttc tggaatcgta attgaagcga tttggttaag aggagtttcg actccatagt
     5041 attctacatg tacacggtca agcaagcttg cattggcacg accagcacgg ataccaccaa
     5101 attcacgagc aagtgattgg tgagattggg tcattctctc tttagctttt tcaataatta
     5161 cgttagccat attctttctt attccttttc ttcgatatta tttgaaactg ttgttccgat
     5221 attttcacca aatacgacac gtttgatgtt gcctgattgg ttcatgttga agacaaccaa
     5281 gtcaatgtcg ttgtccattg agagggttga ggctgttgag tccatgatac gaagaccttt
     5341 gttgataaca tcacggtggg tcaattcttc aaacttaacg gctgtcttgt ccttcttagg
     5401 atcggcattg tacacaccat cgacgccatt tttagccatg aggatggcat ctgcttcgat
     5461 ttcagctgca cgaagggccg ctgttgtatc tgtcgagaag tatggtgaac caattccagc
     5521 accaaagata acgatacggc ctttttcaag gtgacgaagg gcacgtccac ggacataagg
     5581 ctctgccact tgttgcatag caatagctgt ttgtacacgc gtatcaaccc caacttgttg
     5641 caatgaatct gccatcacaa gagcattcat aacagtccca agcattccag tgtaatctgc
     5701 ctgaacacgg tccatacctg cttctgctgc aggttctcca cgccaaagat ttcctccacc
     5761 aataacaagg gcaatttcga tacctaagct atgaacttct tgaatctctt ttgcgattgt
     5821 ttgaactgtt tggatatcaa tccctacgcc acgttcaccg gcaagggctt cacctgataa
     5881 cttgattaaa atacgtttat acttgggatt cgccattttc actctccttc tttcatccta
     5941 cctattttat cacaatttct aagattttta tagtatcatg agcaattctt tcaaaaaaat
     6001 tagacagtca aaaattcctc taagtcggca agggcacgct ctgcaatttt ttcataacga
     6061 gccttcttat cacggatacg ctcgccttcc aactccttga tgatcccaaa attgacattc
     6121 attggttgga aatgtttgct gtcggcatgg gtaatgtaat gagctaagct tccaatcgct
     6181 gtcgtctcgg ggaaaataac ctcgctttct tccttgaaga gacgagctgc gttaattccc
     6241 gcaactaagc ccgaagccgc cgactcaaca tagccttcca cccccgtcat ctgaccagca
     6301 aagaagagat ttggttgttt cttggaacgg taagtctgct caagaagatt tggtgaatcc
     6361 atgtaagaat tgcgatgcat gacaccataa cggacaaact ccgcattttc aagacccgga
     6421 atcatttgga agacacgctt ttgttctccc catttgaggt gggtctggaa accaacaata
     6481 ttgtagaggc taccagctgc attatcctga cgaagttgca caaccgcata aggtgtttta
     6541 aattctccat cacgaggtcc tgtgtagtcg tccggatact caagaccgac tggcttcata
     6601 gggccataaa gcatagtttt aatgccacgt ttggccataa cttcgattgg catacatcct
     6661 tcaaagtact tttctttttc aaaagaattg agcggtgctt cttccgcatt gaccaaggct
     6721 tcatggaaat ccataaactc ttgcttggtc attggagcat tgagataggc tgcttctccc
     6781 ttatcataac gagatttgag atagacctta ctcatatcga tagtgttgac atcgataata
     6841 ggcgctgctg catcgtagaa atagaagcca tcgccattat taagggcatg aatcttttca
     6901 gccagggcat cgctagtcaa gggaccagtc gccacaactg taataacatc tgttggcaat
     6961 tctgtaattt catcacgcac cacttcaatc aaggggtggt tgaccacttt ttcggtcacc
     7021 atttgagaga aaccatcacg atccaccgca agggctccac cggcaggaac acgtgtagcc
     7081 tcagcagatt ccaagataac agaacccaag cgacgcattt cttccttgag aagaccaact
     7141 gcatttgtca aagcatcccc acgcaaagaa ttggaacaaa ccaactcagc aaaattgtct
     7201 gttttgtgct gaggagtcga cttgacacca cgcatttcat aaagtttaac tggaatacca
     7261 cgctctgcga tttggtaggc tgcttcagaa cctgccaaac cagcaccgat aacattgata
     7321 taagattgag acacgacact aatacctctt tgggagtgtg aagttaagat tcacattgaa
     7381 aaagccaatc agacttacga gatttcgagt ttcttggctc aggctgaaaa agtcccccag
     7441 actttcctcg ctctcgaatt tcttggctca agctgaaaaa gtcccccgga ctttttcact
     7501 cccacaaatc tttctatttt tttcttctac tagtataaca aaaaaaggga agaaggcaaa
     7561 cttccctgtt tagtcatttt cttgatgtaa agagatagag agtattccag ttaagaatca
     7621 attatatgct actctataaa atcttttcca cataacggat cgatagggac tgttattcta
     7681 tctcttgcta taaccgtatt atctaaaaca gcataacatt caacatagtg atctccttta
     7741 aactgtgaat cttcgtgata ttttatttta cctgaaaaaa tagcaccacg ctcacaattt
     7801 cttctaatag cctcagcttc aatatttctt actttccaat agacttcctg cgaaacaaaa
     7861 tatggtatag tagttctatg aatgatgaag caagtaaaca actaactgat gcacgattta
     7921 agcgtcttgt tggtgttcag cgcacgactt ttgaagagat attagctgta ttaaaaacag
     7981 cttatcaact taaacacgca aaaggtggac gaaaacctaa attaagccta gaagaccttc
     8041 ttatggccac tcttcaatat gtgcgagaat atcgaactta tgaacaaatt gcggctgatt
     8101 ttggtattca cgaaagcaac ttaatccgtc ggagccaatg ggttgaagta actcttgttc
     8161 aaagtggtgt tacgatttca agaactcctc tcagttctga ggacacggta atgattgatg
     8221 cgacggaagt aaaaatcaat cgccctaaaa aaacaattag cgaatcattc tggtaaaaag
     8281 aaatttcacg ctatgaaggc tcaagcgatt gtcacaagtc aagggagaat tgtttctttg
     8341 gatatcgctg tgaactattg tcgtgatatg aagttgttca aaatgagtcg cagaaatatc
     8401 ggacaagctg gtaaaatctt gtctgacagt ggttatcaag ggctcatgaa gatatatcct
     8461 caagtacaaa ctccacgtaa atccagcaaa ctcaagccgc taacagctga agataaagcc
     8521 tgtaaccatg cgctatccaa ggagagaagc aagattgaga acatctttgc caaagtaaaa
     8581 acgtttaaaa tgttttcaac aatctatcga aatcatcgta aacgcttcgg attacgaatg
     8641 aatttgattg ctggcattat caatcatgaa ctaggattct agttttgcag gaagtctaat
     8701 gtaattctca agctgtgagt tcattatgat ttgtaaatcc gatatatctt cagcagctaa
     8761 aaacacattt tgaaatgttc caagtccgtt ttcaccaaaa ctatattctc tcttactata
     8821 cttactctta ttattctcta tatagttaga gtcaaggttc ttaacctctt gaagttcatt
     8881 ttctttactt ctgaggttaa aatcttttac ttctgaagtt aagttttttg acttctgtaa
     8941 gtcattttct tttacctgaa atatactcat aaagtcttta acataaatga tgttcggctt
     9001 accaagtcca agccttactc tttcgatcag tcctattcct tttttacatc aagctcatct
     9061 aatgttttta tggcagttgg ctttgagata tttcttcttt tcataatttc ttcgacagta
     9121 aaatagataa atactctgcc ttccttgtct atccagttat tcttaaatga cattcctgtc
     9181 tgtttaagaa gtatggaata aaggataatt gcttctgctg ataagccccg aaattcttct
     9241 ctatcaacta atatctccgg tacttttaag aagttaaatc tttccgcttc tctgttataa
     9301 aaatattcaa agtccatgca agatcacctc ccttcttaaa aatttgcaaa gaaaaagacg
     9361 atagtttttc ttctatcgcc tttggtaacc atttttatga aattttttaa agttaaaaat
     9421 ataatttata atactatctt cttccatttt ctgattttag ttctgaaagt tccaaaaggt
     9481 gcaaccgtat ttacatgaat aaacttatac acttcccaag tcgctgtttt agtcgcttca
     9541 tcagcccact ttctcatatg cggttcaaat aattcttcct cactcaacga atcaatcatt
     9601 gcagagatag aattaatatt ttcatttaat tttgctttca actcttgcag agataaatga
     9661 gcgtaggtat ctgtgaacca ctgatataat tcaccaagtt gattccattt aaatttatcc
     9721 gatggtgttt ttacttgaag cccctttctt tcatcttctt cccatttaag aaccaagttg
     9781 gtccaaccaa cctgataagc aaggttttct gctggagttc tgtcaacttc atcagctctc
     9841 ttatctttta aattttctgg aatattatca aattctaaaa tatatttctc aaatgttttc
     9901 tctatctcag cttttagttc ttctttattt tcgtatgttc gcaaaaaatc accttctttc
     9961 tgatttatca atcctttgat ttaaaatgac cttatttttc tatttatacc ttctaagaac
    10021 gctataactg ctgctccaac catcggtatt ccgtatgggc ttaataaaaa acttaatacc
    10081 aaagcttcta taccaagtga tacatcttta tattatcatc actaattaag ttaaacagaa
    10141 acagacagaa ttattacatc ctgtctccct ttattgtttt tcttcccagt cgtggtaggc
    10201 agcgtagagc tgacttttat tccactggta aatcttagcg acttccttga tagcttggtt
    10261 tttcttcaca ccttgctgga tgcgggtttg aatttctacg aacaagtctt cctcgtcctt
    10321 ttcctccaca ccctgactgg caccctcaac aatgagaaga cattcgccct tgagtggcgt
    10381 ttcagcaatg ctttctaata actcagagat agtacctcgt tggtattctt catagatttt
    10441 ggtcaattcc ctgaccaaga caacggagcg gtcaccgtag acttctaaca tattttccaa
    10501 cgtgtctgct acacgatgag gtgattcata aaaaatctgt gtttcaggat aatctttttt
    10561 caagccaaaa aattgcttct gctgacctga ttttctcggt aaaaaaccgt aaaagatatg
    10621 tggctgtggc gctaaaccac tggcaatcaa ggcagaaatt cctgcagagg cacctggaac
    10681 tgtcacaact gcaatttctt cctcaatagc tgccttaact aaatcatgac cagggtctga
    10741 aatgctaggc aaaccggcat cagagacctg agcaatactt tgccctgctt tcaagaaacc
    10801 aatcaaatca ggaatttttt ccttggcatt gtgctcatga aaactgatct gcttggtgga
    10861 aatgtcaaaa tgcttgagca aaagccctgt attgcgcgta tcctcagcag caatccagtc
    10921 cacttctttc aaggtctgga tagcacgaaa agtcatatca tctagattgc caatcggcgt
    10981 tgccactaga tacagcttgc catagggaga ctgcacctta aaactttttt gaatttgcat
    11041 gcttactccc tgtataacaa ctcatcacag aacatacatt cttcgtcctg ctctcgacgt
    11101 tgtccataaa aatcattaca tacgtgaaat ccatcacggt aaatacgacg gacactttcg
    11161 cgaacatgct tggccttgac gggagcgtct gcttccacct cacccaagcg ttctcgcaac
    11221 ttactatttt ccaagcgaag agctgtattt tcttctacca agctcttgag atttttcttg
    11281 atggcttcca catcggctaa ggttaccaat aattgttggg aaaaatcatc cagcgcgtca
    11341 aataattctt ttttgtccat aaaacagccc tttcctttct ttatcattca tttttgagtt
    11401 tatatttctt tcaagaccag atattccatg gcattttgaa agctgacatt agcttgccac
    11461 atttttctag cttctagtaa atcttgtaga atcactctta ctcttacctg caagaggtcc
    11521 tgcccacaga gaacttcaag aatccgtaaa acctgatcct gtttttcctt atcatctgcc
    11581 aagttggcta atttggcaac ctgtagataa ctttcttttt tcttagctac taaccaagtc
    11641 agcaggcgtt cactttcatc gaccaaggtc caaaaacttg cctgattagc caacttttct
    11701 gcttcagctc gcgattgact aaacttagct aaaagagtcg cttttttctt aacaagtccc
    11761 atttgttcta agagtaagat aagtttttct tcttgctttt taaagtggaa gatctgagtc
    11821 cgacttcgga ttgtcggtaa catcttttcc tcatcgctag tcaagaagaa aatataaact
    11881 tcactctggg gttcttcgat gaccttgagc agagaattgg ctgcgttggg atgcatttta
    11941 tccgcttgct cgataataaa gacctgttgc tggctttcaa tccctgcttg agaaaactgt
    12001 cccaccaatt cccgaatgcg ttctgtcttg atgacctgat tgactggctt aatcaaggtg
    12061 acatctggaa actcttcctg ttcaatcagc ttgcaacttc ggcatttctc acatggtaag
    12121 acgccaactt tatccgtaca aaagaggctc ttagctaaaa attgcgccat ttccaagctt
    12181 ccaaagaaac ctgaaaagag ataggcgtga ttgagctggt cttgttctaa gatacggaca
    12241 aaacggtcaa actgagctgg ttgccaagcc tttagttgat cttgtttcat ttggccaagt
    12301 ccattccgtc aaacaagaca gccttggtag tttccacaac ttgctccaaa gggagactag
    12361 catcaatctt gacaatgcga tttccttctt tttccaggag agaaaggtag ccttgacgga
    12421 ctttcttgtg caattccaaa ccttccaagt ccagacgatt gacctcgcgg tcactattcg
    12481 cagcaatgcg agccagccct tcttccacct cgatgtcaaa atagagtgtc aaatcgggtt
    12541 tgaggccatc tgtcgcaaac tgattgagcc agtcaatggc ttcaatatct aagccacgac
    12601 caaatccctg ataggcaaca gaactatcga taaaacgatc catgatgacc aacttgccag
    12661 cttcaagggc tggaagaact ttttccacca aatgctgtct gcgactggca atatagagaa
    12721 gtagctctgt tttagcatcc atctgagtat gacttggatc caaaatcact tcccgaatct
    12781 tctccccaat caagactccg ccaggttcac gggtcgtcag cacctttact cctttttcct
    12841 ctaaaattgg tagcagagcc tctaaaacac tggtcttgcc tgctccctct ggtccctcaa
    12901 gagagactaa aaatcctttt gacatgtcta actcatttct tttttactac ttctattcta
    12961 tcaaaaaaat aggggtttgt gacaatcttt ttgtcttctc atttcatact caatgaaaat
    13021 caaagagcaa actaggaagc tagccgcagg ctgtacttga gtacggcaag gtgaagctga
    13081 cgcagtttga atttgatttt cgaagagtat caaccaccat aaaagaggca gataaaacta
    13141 cctcttattt acctagttct tgtgttcgtt tgtaggcttg atgaactgca tccatgactg
    13201 ttcctcggaa agcatgcgct tctaggcttg ctacaccagc gatagtcgaa ccgcctgggc
    13261 tacagacttg gtctttcaat actccaggat gttgctgact ttcaaggacc aattgcccag
    13321 ctcctaccac agtttgtgct gccattttca atgctatttc tcgtggtaat cctgtctgaa
    13381 cacctgcatc tgccaaggcc tcgataaaaa gatagacaaa ggctggtcca caacctgcaa
    13441 gacctgtcgc tgcatcgatt aaactttctc ctagttcaac caagagacca gccttggcta
    13501 aaagctgata aaagagctca ctgtcctcag ccctgcaatt aggagacaag gcataactaa
    13561 tcactccttg cccgatagaa gcaggggtat taggcatcat acgaataatt cggtgttgac
    13621 ttgggataag acttgctagt ttttctaagg tcaatccagc tgccatcgaa atcaaaagaa
    13681 gactttctct tttttcaagg atggtctggt attgagaaag cagttcagaa aactgagcag
    13741 gcttaactcc tagaaaaatc acatctgctt ctgcaaacat ttcttcattg ctggaagcct
    13801 gaccaccaaa gtctgcaatg aaagcatcta ccttagcttg actacgattg gcaaggagaa
    13861 tctcatctga cgtcctagtc tgcaagacag attttgccaa gctagcaccc atattcccca
    13921 aaccgataaa tccaatcttc atctcttact cccttatctg cccatcaccg gcaaccacat
    13981 acttgtagct ggtcaactct ttcaagccca tgggaccacg cgcgtgcaat ttctgagtag
    14041 aaatccccat ttcacaacca agaccaaatt gtcctccatc tgtgaaacga gttgaggcat
    14101 taacatacac cgctgcagag tccacttgat ctgtaaagta tgctgcagct tcagcatttt
    14161 ccgtcacaat agcatccgaa tgatgggtgc tgtgggattc aatgtgcgca accgcttctt
    14221 ctaaactgct cacaacctta acagcaagga catagtctaa aaactcggtg tcaaagtctt
    14281 gggtctcagc tgcttgacct gaaacaaact ggcttgcttt gctatccaag cggaattgaa
    14341 ttggttccag tccagcttcc ttacgctctg caaccagcat ttgatccaag cgaggaagga
    14401 tgcttgctgc cttgttttca tgaaccagca gaacctccat ggcattacaa acagaaggac
    14461 gactggtttt agcattgttg atgatagaca gcgccttgtc ttcgtctgca tccttatcca
    14521 catagacatg gacaatccca gtccctgtct cgataacagg tacaatcgca ttctcaacca
    14581 ctgcattgat caagccagct cctccacgag gaatgagaag gtctagatag cccttggcct
    14641 tcatcatagc ataactactt tcacggctag tatcctccac cagttgaatc acatttggat
    14701 gaatagtagt cgtctccaag cccttcttca aggctgtgac aatggcatgg gttgtttgat
    14761 aggcatcctt accactacga agaacaaccg catttccact cttaagagtc aaagcagccg
    14821 catcagacgt cacatttgga cggctttcat agataatacc gatgacacct atagctacac
    14881 gtttttttgt gataaccaaa ccattttcaa gctgacttgt ttctaaaact tcaccgattg
    14941 gatctggtaa ggcaaccact tcacgaattc ctcttgccat cgcttctata cgatctgcat
    15001 ccaaataaag acgatccaac atcacatctg agattttccc cttagccgct gccatatcga
    15061 gggcattagc cgctaaaatt tcctcagtag cagccactaa gtgatcagcc atggctagca
    15121 aggcttggtt tttcacttct tcactagctg tgttaatcga ttttttaaca gcctgtacct
    15181 gttcaaattg ttcttgtcta ctcaccatag tttacctcta aaattctgta aaaagtagtt
    15241 ggatttcagg agtaatggaa atccagtcgt cacggtaaat caagacaccc ttggcttttt
    15301 gagaacgcaa catatcctcc aaagcagatg ctccaaattg cacgcgtcct tttccaagtg
    15361 attttccact ttccttgtca aatactgtca cgatatcacc gtaagaaaag gctccttctg
    15421 cttcaacgat accagataag agaagactct ttccatgttg agagagagct tccgcagccc
    15481 ctttatcaac ccaaatagaa ccttgactct gagcatagaa ggcaagccat tgtttctggg
    15541 tacgaagccc cttctcttga gcaacaaagt aagaaccatc ctcggtctcc tctgccgcct
    15601 caatcatgga atctgatttc aaggatgagc agatataaac aggaactcct gattccgtcg
    15661 cgatagttgc agccttgatt ttggttaaca tacccccagt tccgtttgac gaaccagctc
    15721 caccagccat atcaataatc tcacgattga tggtctcgat tctctccaag cgtttggctc
    15781 ttggatctga attaggattt ccagtataga gaccgtccac atctgtcaag aaaactaaaa
    15841 ggtctgcttg gaccatcgcc gctacttgag cacttagagt gtcattgtcc ccaaccttga
    15901 gctcatcaat aacgacacta tcattctcat tgatgatagg aattgcccca cggttgagca
    15961 aaaccgacaa agcctgatgg gcatttttat aacgacgctt atccacaaag tcatcttggg
    16021 tcagcaagat ttgtgcagaa acgatttgac gcaagagaag attggtcgta tattcttcca
    16081 acaaaagtcc ctgccctacc gctgctgaag cctgtttatc agcaatttta gtcggacgct
    16141 ttttaaatcc taaggctcca aaaccagccg caatggcacc tgaagacacc aaaatcaact
    16201 catgaccagc ctcgtgcagc atagccaact gctgggtaat atcctttacc ttactacgtg
    16261 ataaacttcc atcctcattt gtcagagaag aagtacccac cttaaagaca atccgtttgt
    16321 atttcatagt ctcactccga ttattcatat ttatccatta taacatgaat aacaggaaat
    16381 agaaaagagt tgataggaaa aagaaggccc taaaaccttc ttttctacta ctgttctgat
    16441 tccgatttgt ttacactcgt ttcagagctt tgtgaagttg aggatgtcaa atcttgacta
    16501 gttgaaaaat ttgtaacact ttcatgttga ctcgtttctt tattttcaag atcctttttc
    16561 actacttctt tggattcttt tatttctgaa tgacttgtag ttttaattgt agcagatttc
    16621 tcgatcgaaa catccactaa ccaggcacca cttgaatcca cagtataacc ttctggtgtc
    16681 ttaccgttca caagtaattg accattttct ttcaagaagt accatttatc cttgtccttg
    16741 atccaaccca cagctcgtga accgtctgtc ttgtagaaat accaatcatt tgccttttta
    16801 tgccagcctt gcttcatagc tcctgaatct tccagataat aatgttgacc agcaacttct
    16861 atctcacctg tcttcatgac accagtagaa tccatatagt accaggtttc tttatctttt
    16921 acccagccca ttttcatttc ccctgatgga gcaaagtaat accattgccc catatattga
    16981 agccatcctg tcttcataga accatcaaca tccaaataat accactgctc tttatcttga
    17041 atccaaccaa tttccatctg gttttctttg ttaaaataat accagattcc agcgattttc
    17101 ttccaatttt tagcagaagc accagagtct gtcaaataga accaatgatt gttccatttt
    17161 ttccattgat tctgtaacaa gatacccgtt tggttaaagt aataccattc accttcgatt
    17221 tcattccaac cgacagcata ctctcctgta gaatcaggcg cttgatacca ccagttccca
    17281 tatgcactct tatgccaacc agcttgaaaa cttggaatcg gcttgtagga tgttgaaata
    17341 ttgacaaaac cgtcttttcg aatatcaaaa actgttgcat catagtcttt gctggctgcg
    17401 ttgattctct caattcctcg ttctttgagc caattaacat actcactatc aacaccattt
    17461 ttccaaggta gactatccga agtttgaaca atcaaactcg gactcaaatt tttaatgaaa
    17521 tccttggtat ttgatttgtt ggtatcatgg tgatgattaa acttcatcaa atcaactttt
    17581 ccaatgagag gaccatactt gtcttctgct ccatgaacat tatctaaatc gcccccaagg
    17641 taaattttct tgccattgac tttcaccacg ctaatcaagg aattggaatt gtcatcccaa
    17701 attttcttta attcacccga tgaatcagtt tcattttcat aattatagag ctgaatatcc
    17761 atgtccccaa actgaaaatg agcatcccct tgtgtgatat tttgaataac tgaaacacct
    17821 ttttctgcag cagtctgtaa aaccttatca tagccataca gattatccca tagacgttca
    17881 gaattagtaa tacgactatc actatatttc ttaagataga ctcggtcaac tggataggta
    17941 gacagtaatt catcaacatt tccaatatga tcactgtggg tatgggtcac caaaataaaa
    18001 tcaagttttt ggacacccaa ttccttcaaa cgacgaaaga cacggtctgt tagaacatgc
    18061 ttataagacg tttcaattcc ttctctccat ggatagcgag aatcacttcc atctgggaaa
    18121 tcataatctt ctcctgtatc caccatggca aaatgtccat tgctttcaag aataatcgca
    18181 tcactgccac cttcttgaac attgataaag tggattttat ttcctgaact ttcttgagcc
    18241 tgaacattcc cataccatga caaacctaaa aaagcgccta caagtgctaa actagttaat
    18301 ttctttttca ttcttacttt ctcaatctct ccaaggtttc cttaaaaatc tctgggatat
    18361 ctgctttaaa ttccaaggtc ttacctgttc tcggatgagt aaaacctaaa gtcttggcat
    18421 gaagaaattg tccatgtcct ttcaaagtct tgcgaggacc atagacctca tcaccagcga
    18481 ctggatggcc gatataagcc atgtggacac ggatttgatg agtgcgccct gtctccagtt
    18541 gcaactctac taagctataa tcgccaaagc gttccaagac gtgaaaacgc gtcactgcag
    18601 gcttcccttt agcagttaca gcctgtttct tacggtcttt ttcactccgg ccaatcggcg
    18661 cttcaattac accacgatca ttaggtagat ttccatgaac aatcgcccaa tatttgcgga
    18721 gagacttttt atccttgagt tcttgggcaa gtgctagatg cgcatcatcg tttttagcaa
    18781 tcatgagaag acctgacgta tccttatcaa tacggtgaac aatccctgga cgcagaaccc
    18841 cattgatacc cgacaagtcc ttaatatgat acatgagggc atttactagg gttccactgg
    18901 tatgaccagc actcgggtgc acaaccattc cctgaggttt gttaacgaca gccacatcct
    18961 catcttggta gactatttct agcggaagat cctcagccac atactctaat acctctggtt
    19021 ctggcacatg gtaagtgacg acatcaccct cttggactgt gtatttagct ttcttgactt
    19081 gaccattgac caagacctgg cctgatttaa tttgttcatt cgcgagacta cgtgataatt
    19141 ctgacaaatc tgacaaagcc ttatccaaac gcagaccacc agtttcaatt ttaatttcca
    19201 tttatttcct cttttagcat tgcaatcaat aaaataatca ctccaaccgt cagatagcta
    19261 tctgccacat tgaaaattgc aaagttgata aagtcaaggt ggaacatatc cacaacaaag
    19321 ccctgactga ccctgtcaat aaagtttcca agaccacccg cgattattag agtcaaaccc
    19381 aagaccatcc agaatgagtc ctccatgtgt ttatgtaaat accaaatggc acctatcacg
    19441 acaaccagag taatgacagc gaataacaac tgctgatctt gtaagataga aaaggctgca
    19501 cctcgatttt gcaggtaggt caagctaacg aaattgggga tccaggagcg cacttcaccc
    19561 agtggaatct gctggacgat ataggatttg accaactgat ccagcccaat caaaagcagt
    19621 acaatgactg ccactattgc tctttttttc atgatttcct cttttgatca aaatattctt
    19681 gcatgacttc tacgaagaga gtcccagctt gactaagctc cacttcttca cgtttaacat
    19741 agaccatgcg gttatctagg ttatccttga gacgaataac tgtaatgcca ttaacactgt
    19801 cactatctaa aaatccagaa cctgtcgcat aggcgtccgt ccgctccaaa ataccattca
    19861 aggtggcacg gtctgtcaca ttaaacatct gtgagctagc gctggtatca acaaagttct
    19921 ctgaataata aaggtactcg tctttctctt gagtgaaacg aaccgttggt aaatccgcta
    19981 aatcctccat gactaattcc tctttctggg ctaaaggatg accctcacag agataaatat
    20041 gggtatggaa aggaatcaat tcgatgacct ccagacctaa cttttcaacc cgttgcataa
    20101 tccccttttt attttgattg ttgaggtaga taatcccaat ctcactatgc ccttgcgcca
    20161 cttcatctaa tatttgaaca gtagttgatt caaaaatacg gaagttctta tagtcaggat
    20221 agcgctctga aaaggccgta atagttggtg gtaagaagtc atagtgctgg ctagcaacgg
    20281 aaaattcatc tttttcttct tcaggattgg catactgatt ttgaaaaata tcaaatcctt
    20341 taaccaattc ttgcgctttt tcataaaatt ccatcccacg acgggtcaag aaagtccctg
    20401 agctggtccg acggaaaatc ttaaaaccca actctttttc caaatcccga acagaaatag
    20461 acagactcgg ctgactaaca tacatctttt cagcagcttc acgaaaagta ccactattgg
    20521 caatagccac aacatagcgt aattgttgaa tgttcatctt ctacccctaa cttctttatc
    20581 ttttcattat accatatttt agaagttttc caaaaaggaa aaaagaacat cctattcttc
    20641 ttaactatct tcactatctg cctttctcac gccaatctta ttttcaaaat caattcaaaa
    20701 aaataagtgg ctacacacca cttcagtatc ggaaagaaaa acgttgacta tttgtgaaaa
    20761 aagaaaatgc cggaaaattc cgacattttt ttagtaagct aacttcctga aaataggagt
    20821 aaccaaacat cccagaaggc agtgatattg atgagaatat gaactagtat tggatagtag
    20881 agatttttag tcatgcgata caatagagct aaaatcagac ctccactagc ataaatgaaa
    20941 aaagcaagag gagttaaagc aaaattgata tgaatataac cgaaaataat agcagaaagc
    21001 aaaacatctc cgtaccaagg tgagtttttg aaaaaggttg tcataagcac acctcgataa
    21061 atcaattcct cagcaatagg ggcgatgaag caaacgatga gcaagaaata agggaactcc
    21121 tgtctcccca tcatttctat cgtttcattc aaagaaatct gatttgaaga cagggatatg
    21181 aaatacgaaa agaggaagtc agacatatat gaaatgatgt agcccagtaa aaggtagatg
    21241 aagtacctca gctgccactt gaaatgaaaa attttctttc ctgcaaaaac cagtagatag
    21301 atgaccgcta agaaaagaac tccgctctcc atcaaaagca gaatctgaaa aaattcacga
    21361 cttgctggta gatagggctt tgcgaggtga ttgaaaactc tccaaaacca agttgatttg
    21421 taaaaaatta aggacaatgc tagtaaaatt tgaatagccc gttttttcat attaaattct
    21481 ctgctttctc cccttgtttc ttcatattac taataaattt tacttaaaat ctcgcagcac
    21541 ttcctttgca aagatgattg cctcctccaa tatatcctaa atcataggtg cctctgggac
    21601 aaaatccatg aaccggcaga gttaatactg gttctatttc ccaatcgtac ctaccattag
    21661 gatttttacc atatgaatct gctccacctt gtatcagctc taattcttca tttgttagat
    21721 ttatattttt tgtcattaaa atcatgatat atttcctcca ttattcttca gattagttga
    21781 gtaatctgat actcatacct acttacaaaa aaactattat attaagttgg ttttttaatt
    21841 tgtctagttg caacattgac aaacatagta tagcatatct ttgcgaaata tcctcttcaa
    21901 atcatgaatt gtcatcaaaa catcttaaac tataaaatca attagtctca agctttctat
    21961 caatttcttc tccaaaatat gctataataa tagcaaaaga taaagaagga agacctatga
    22021 ttaaactact agccttggat atggacggca ccctcctcaa tgaagccaag gaaatcccac
    22081 aagctcacat tactgctatt cacaaagcca ttgaaaaagg tgtcaaactg gttctctgta
    22141 cgggtcgccc ccttttcggt gtcctcccct actacaaaaa actgggactc gacctccaga
    22201 atgagtatgt gattgttaac aacggttgtt caactcacca gactagcgac tggggcttgg
    22261 ttgactggca agaacttagt ccagctgaca tcgaatacct ctatgacctt gctgaaaaga
    22321 gtgatgttca gttgacactt tttgacgagt cacattattt tgttctcggt ggaaagccca
    22381 atcaagttat tgaaaatgat gctaaactag tattttcaga cctgactgaa atttctcttg
    22441 aggaagcgac tagtggaaag ttccggatgt tccaaggtat gtttttagga acaaaagaac
    22501 aaacagacga ttttgagcag cgttttgctg aagagctttg ccaacgattc agtggagttc
    22561 gttcgcagcc tgtcatttat gaagcaatgc cacttggaac gacaaaggct actgctcttt
    22621 cacgactagc tgagattttg aagattgatt cctcagagat tatggccatg ggcgatgcta
    22681 ataacgatat cgaaatgctc cagtttgcag ggcttgggat tgcaatggga aatgccagcg
    22741 attatgtcaa atctcttgcg gatgccgtta cctcaagcaa cgaagaagac ggcgttgcgc
    22801 gtgctattga gaaatatatt ctataaaaaa gaaaagcaaa tagacagaag ttactgctat
    22861 ttgctttttt gctaatattt taaaatacgg actaatcaat agagaagaat agcgaatcat
    22921 aaaaatcgat ttactagatg ccatagtatc ttatagttgc taataagaag ttagtctagc
    22981 agaatgaatc tctcatttct cccacactaa tctgtaattt gtctatacat ttctggtctt
    23041 ctatctcgaa acaagcccca gtttaggcgt tcacttgctc ccttgtctag gttataagta
    23101 gctaacagaa cagcttcttc ttgtctttca gctcgttcta gaatagctcc tgtttcatcc
    23161 gtcataaagg aggaaccgta gaagtcaaga ctggaactct gtccgccatt ttcctcacta
    23221 ggagtaacct cctctaaacc ataacgattg gctgcgatga ctggaacaat attcgctgct
    23281 gcgtgccctt gcatagtacg ttgccagtga ccacaactat ctgtatccaa aatcggctct
    23341 gaaccgatgg ctgttggata aaagagcaat tcagcaccat tcaatgcaag acagcgcgct
    23401 gtttcaggga accattgatc ccaacagata ccgataccaa tcttagcata gcgagtattc
    23461 cagaccttga aaccagtgtt accaggcgtg aaatagaatt tttcttgata ataatggtca
    23521 tctggtatgt gggtctttcg ataaacgccc agcacttccc catctgcatc aatgacggca
    23581 atagagttat acaagacatt accatctttt tcatagaaac tgattggtaa aacaacttgt
    23641 agttccttag caatcacctt aaaatgctga atggcagtat tttccgctac agattgggca
    23701 tactggtagt agtcatactg acgttcctga cagaaatagg gatgttcaaa caactcgggc
    23761 aagagaataa tttgggctcc ttgctcagca gcctgacgta ctaaacgctc tgcggtttgg
    23821 atatttgttg ccacatcctt agcgcattgc atctgaatgg ttgcaactct tacatttctc
    23881 atctttttct cctattctgg aatttgttgg gtgatacagt ggatattgcc accacctaag
    23941 agaatatctc tggctggtat tccgacaact ttacggtctg ggaaacactt gctgaggata
    24001 tctaaggcca cttggtcgtt tacatcctca aactgtggaa ccaagacagc cttgttggcg
    24061 atataaaagt ttacgtagga agctgctagt cgttcacctg cgtatcgctt ttcttctcct
    24121 tcttcataga tgtagcctgg caaatcttct tctgtcacaa cttgtcgaac tgcagggata
    24181 ggcaatttat gaatggtgaa gtgacaacct tttgcatctg tttcctgttc taagagttcg
    24241 agatctgctt ttgacatggc atactgggga tcattttcgt catctgtcca agccaaaaca
    24301 agctcagcag gaccaacaaa ggcagcaaca ttatcgacgt gttcattggt ttcatcctga
    24361 taaataccat aaggaagcca aataactttt tcagcaccaa gactttctaa taatgtgttt
    24421 tcaatctcct ctttagtcag gttaggattg cgaccaggac taagcaagca actttcagtt
    24481 acgagaatag ttccttgacc atcgctatgg attgcgcctc cttccagtac aaaaggttta
    24541 gcatcataga caggcctttc caaggcctca gcaaaacgac tggctacttg gtcatcctct
    24601 tcataatctt gataaagacc atcataggtg cctccccaag cattaaaggc ccaatccacg
    24661 gctaatttct tacctttatc attgacgaga atggttgggc cagtatcacg cgcccaggca
    24721 tcattggtgg gaatgtctaa ataaacaacc ttgtctccaa gataggattg ggcttcagat
    24781 agataggcct gctccaccaa aagatagact ctttcccctt ctgctatggt ctcgatgatc
    24841 tgagtaaatg ctcttttagc agcctttcct tgaaaaggcc atgatcctgg tcgagtcggc
    24901 catatcatga gggtaccatg atggggttcg tactctgctg gcatgtgata gcctaatttt
    24961 tttggactgt ccatcatgat aatctccctt taaagtcttg atagccaaaa gctttgagta
    25021 agctacagtc tccctgttcg tccatgagat agagacttgg caatccaata ccattaaagg
    25081 tattattttt gacaaaagaa taaatggcca tgtcttgaaa ataaagtctg tctccgattt
    25141 ggactggatt ttcaaaacta taatcaccaa tcacatcgcc cgtcagacag gtattagaag
    25201 aaagtctgta ggtatgggct ttttcctgtg actcaaagcc atttctcaaa ggtggacgat
    25261 agggcatctc aagtacatca ggcatatggc aggtcgcaga ggcgtctaaa accaagattt
    25321 ccataccgtt ttctacaata tctaatacct cagttgctaa ataacccgca ttaagcgcaa
    25381 tggcttcacc aggctcgata tagatttcaa gattgtaagt ttttcggata cgcttgattt
    25441 ctgaaatcag caaatccaca tcgtaacctt ctcttgtaat atgatgacca ccacccatat
    25501 tgagccattt tacctcatgt aagtagggac caaactgttc ttctactgct ttcaaagttg
    25561 tttgtaaatc atctgctccc tgctcgcaaa gggtatgaaa atgaagtccg tcaaccaaat
    25621 ctagcaaatc actcggaatc ttgtctatag taactccaaa gcgagaacct ggtgcacaag
    25681 ggtcatagag cgcgtgatct ccttgagttg aacactgagg gttgaggcgc aaaccaacac
    25741 tgacaccagc ctctcgacaa cgcggaccgt gtttacgcaa ctgtctctct gagttaaaga
    25801 cgatatggtc cattatctct agcaattcct ccaagtctgc atccttgaaa gcaggcgcaa
    25861 atacatggac ttcaccagga aattcttccc ttgccaattt ggcctcatag agtccactag
    25921 ctgtcgtacc tgatagatac tggctaatca agggataagt tttgtagagg gaatatgcct
    25981 tctgggcaag caagaccttg caaccggcct cttcttgtac atattgtaga atgcggcaat
    26041 tagcttctaa cttggccaag tcaataacat aggctggtgt tggtacttgt tctaacttca
    26101 ttagtccacc atttgtggat tttcaaccac aacccatggc aaaccatact cattcaaagc
    26161 ttccatgaat ggatctggat ctaactcctc aaggttatac actccagctt gtttccaagt
    26221 tccgttcatg actaattttg tcccaatcat ggctggaact cctgtcgtat aagaaatagc
    26281 ttgcgaacca acctctgcgt aacattcctg atggtcgcag acattgtaga tatagatagt
    26341 ctttttgaca ccgtctttga cacctgtaaa gatacatcca atattggttt ttccgactgt
    26401 acgtggccca agactggcag gatctggaag caaggctttc aaaaattgaa ttggaacaat
    26461 ttcttggccg ttaaagttaa tggtatccgt acgaaggagt ccaacatttt caagacattt
    26521 catgtgcgtc aagtaagatt gaccaaaagt cataaagaaa cgaatgcgtt tgacacctgg
    26581 aatgttcttg gccaatgatt cgatttcttc atggtgaagg agatacatat ctttttgtcc
    26641 aacttgaggg aaatcatact cacgcttgat agacatagct tcgacttcga cccatttccc
    26701 atcttcccag taagaacctg gcgcagaaac ctcacggaga ttaatttctg gattaaagtt
    26761 ggttgcaaat ggataaccgt ggtcaccgcc attacagtct aaaatgtcga tataatggat
    26821 ttcatcaaaa tagtgtttga gggcataagc tgaaaagaca ctagttacac ctgggtcaaa
    26881 accagaacca agaagagcag tcaagcctgc ttctttgaat ttctcttgat aagcccactg
    26941 ccatgagtag tcaaagtagg ctgtaaaacc aagttcctta caacgttttt cgtagatagc
    27001 acgccactca gggtcttctg tgtcttctgc ttcgtagttg gctgtatcga tatagtgaac
    27061 acctgttgcc aaacaagcat ccataatggt taaatcttga taaggcagag ctacattcaa
    27121 aacagcttct ggtttgtagc tttcaatcag ggcaatcact tcttcaacct tgtcagcatc
    27181 aagtgctgca gtttcaattt tagtacttgt tttgccttct agcttcgctt tcaagtcatc
    27241 gcattttgac ttggtacggc tagcaatcat aatctctgta aatgtttcgc tatcttgaca
    27301 aatctttgaa atagcaactt gggcaacgcc cccacaacca ataactagta aacgactcat
    27361 ttttttcctt cctcttcttc taaaatgtcc tcaacatact tgggcaacat aaaggctccc
    27421 acgtgtaagt ttgcagtgta gtattctgtg aaaagctggc gttttttcca gccttccttg
    27481 tcaaaatctt tgacagggtg gtattttttc gatgcaaatc caaacaacca atagccagct
    27541 gggctagttg gaatatgggc ctgataaacc cgactgattg gaaaggcttg attgaccttg
    27601 cggtgcatgc ttcggcaggc cgactcatcc tcgtcaaaga agggactccc atgctggtaa
    27661 atcatgatgc cgtcttcctt cagagctcga taactattgc cgtagaattc cttggtaaag
    27721 agtccttccg tatggccaaa tggatctgtc gcatcgttga tgataatatc gtaatcatct
    27781 tcgcagtttc gcaaaaagcg tagcccattt tggtagtaaa tggtaacacg aggatcatct
    27841 agccctgcag caaagtctgg gaaatactca cgacagacct cgaccaacat ctcatccggt
    27901 tccacaatat caatttgctc cagttcagga tagagggtta atacttgggc aacaccgccg
    27961 tcaccacccc caataaccaa tactttcttt ggatttgggt ggacagccat gggaacgtga
    28021 acggtcattt cattgtagac gaaatcatcc gcatctgaga acaagacatg gccatttaaa
    28081 atcagtattt tcccaaaagc tggcgtatcc aagacttcga tatcctgcca ttcacttttt
    28141 ccagcgtaaa gttgcttggc tgttctcaga gacaatttga catctggagt atgaacttca
    28201 gaaaaccata aatccatcta tttctcctta tattatattt agcgcagtta gctactgcca
    28261 aagcccaagt ggtatacttg gaataagcca ctgtggatta gttcatttcc tccaatcgct
    28321 tgacgatttc cgaaaggctc taaccacagc ttttgtttca attggtaatg agtttgataa
    28381 cgcatagacg ttttatctcg tctaaggtaa caaggcaaaa agttcgtgga taaccaagta
    28441 gacttgaaat actacatctg gaggtactcc catgctttat gtgggcattg atatcgctaa
    28501 aaataaacac gatgttacag ccttgaatgt tcaaggaaaa actgttctta aaccactcac
    28561 tttttcaaat aataaagctg gttttgaact cttagatctg tctcttcgac agctcaacca
    28621 agactgtctc atcgctcttg aagatactgg acattatgcc tttaatctac tgaacttcct
    28681 gcatgaacaa ggatataaag tttacaccta caatcctttg ctcatcaagg aatttgccaa
    28741 atcattatca ct
//
LOCUS       DAYYYC010000025        27195 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.025, whole genome shotgun sequence.
ACCESSION   DAYYYC010000025 DAYYYC010000000
VERSION     DAYYYC010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27195
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.025"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(<1..203)
                     /gene="blpZ"
                     /locus_tag="ACHBV5_001169"
     CDS             complement(<1..203)
                     /gene="blpZ"
                     /locus_tag="ACHBV5_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HFM9966971.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLL"
     gene            complement(245..934)
                     /locus_tag="ACHBV5_001170"
     CDS             complement(245..934)
                     /locus_tag="ACHBV5_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HFM9966972.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            complement(986..1369)
                     /locus_tag="ACHBV5_001171"
     CDS             complement(986..1369)
                     /locus_tag="ACHBV5_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HFM9966973.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            complement(1998..2317)
                     /locus_tag="ACHBV5_001172"
                     /pseudo
     CDS             complement(1998..2317)
                     /locus_tag="ACHBV5_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826248.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
     gene            complement(2838..2957)
                     /locus_tag="ACHBV5_001173"
     CDS             complement(2838..2957)
                     /locus_tag="ACHBV5_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HFM9966974.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(3061..3210)
                     /gene="blpO"
                     /locus_tag="ACHBV5_001174"
     CDS             complement(3061..3210)
                     /gene="blpO"
                     /locus_tag="ACHBV5_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HFM9966975.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(3454..3657)
                     /gene="blpN"
                     /locus_tag="ACHBV5_001175"
     CDS             complement(3454..3657)
                     /gene="blpN"
                     /locus_tag="ACHBV5_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HFM9966976.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(3673..3927)
                     /gene="blpM"
                     /locus_tag="ACHBV5_001176"
     CDS             complement(3673..3927)
                     /gene="blpM"
                     /locus_tag="ACHBV5_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HFM9966977.1"
                     /translation="MNTKMMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            4207..6332
                     /gene="blpA"
                     /locus_tag="ACHBV5_001177"
                     /pseudo
     CDS             4207..6332
                     /gene="blpA"
                     /locus_tag="ACHBV5_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
     gene            6343..7704
                     /locus_tag="ACHBV5_001178"
     CDS             6343..7704
                     /locus_tag="ACHBV5_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HFM9966978.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVISSIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     TTQLQRLEKQKEGLGIFKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIVNKRARLPTGNPHQSILNRY
                     LIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            7761..7916
                     /gene="blpC"
                     /locus_tag="ACHBV5_001179"
     CDS             7761..7916
                     /gene="blpC"
                     /locus_tag="ACHBV5_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HFM9966979.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(7960..9300)
                     /locus_tag="ACHBV5_001180"
     CDS             complement(7960..9300)
                     /locus_tag="ACHBV5_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFM9966980.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLLKFLL
                     GIIFTTFQFLAVSKYLSYFIEPLFGIGLSFLLLRGLPKKILIFYGLFPMILVELFYRG
                     VSYFVLPFLGQGIVDGDGNPIFLLIMIFVCFIVLVFLKWLDYDFTRLRREFLDTGFQK
                     SLTKINWAMGAYYLVMQSLSYLEYEQGIQSTTVRHLILVFYLLFFMGGIKKLDTYLKE
                     KLQEELNQEQTLRYRDMERYSRHIEELYKEIRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLRDSSQKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(9314..10051)
                     /locus_tag="ACHBV5_001181"
     CDS             complement(9314..10051)
                     /locus_tag="ACHBV5_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFM9966981.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(10056..10394)
                     /locus_tag="ACHBV5_001182"
     CDS             complement(10056..10394)
                     /locus_tag="ACHBV5_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HFM9966982.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            10670..10999
                     /locus_tag="ACHBV5_001183"
     CDS             10670..10999
                     /locus_tag="ACHBV5_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HFM9966983.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(11167..12216)
                     /locus_tag="ACHBV5_001184"
     CDS             complement(11167..12216)
                     /locus_tag="ACHBV5_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9966984.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(12213..12944)
                     /locus_tag="ACHBV5_001185"
     CDS             complement(12213..12944)
                     /locus_tag="ACHBV5_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9966985.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            13012..13422
                     /locus_tag="ACHBV5_001186"
     CDS             13012..13422
                     /locus_tag="ACHBV5_001186"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFM9966986.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            13432..13719
                     /locus_tag="ACHBV5_001187"
     CDS             13432..13719
                     /locus_tag="ACHBV5_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966987.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            13881..14120
                     /locus_tag="ACHBV5_001188"
     CDS             13881..14120
                     /locus_tag="ACHBV5_001188"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966988.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(14442..15578)
                     /gene="dnaJ"
                     /locus_tag="ACHBV5_001189"
     CDS             complement(14442..15578)
                     /gene="dnaJ"
                     /locus_tag="ACHBV5_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFM9966989.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(15783..16058)
                     /locus_tag="ACHBV5_001190"
     CDS             complement(15783..16058)
                     /locus_tag="ACHBV5_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9966990.1"
                     /translation="MDYNPTEMLVTVERNGNVIYKEFTEVAVGKSKYDHTSVFKDVMI
                     YFSDHICQELHLYKTQDPHYNKFEFDLAKRSLKITTRDNTTIFISNE"
     gene            complement(16150..17973)
                     /gene="dnaK"
                     /locus_tag="ACHBV5_001191"
     CDS             complement(16150..17973)
                     /gene="dnaK"
                     /locus_tag="ACHBV5_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFM9966991.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMSMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSDLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(18453..18977)
                     /gene="grpE"
                     /locus_tag="ACHBV5_001192"
     CDS             complement(18453..18977)
                     /gene="grpE"
                     /locus_tag="ACHBV5_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFM9966992.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(19004..20038)
                     /gene="hrcA"
                     /locus_tag="ACHBV5_001193"
     CDS             complement(19004..20038)
                     /gene="hrcA"
                     /locus_tag="ACHBV5_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFM9966993.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(20202..20711)
                     /locus_tag="ACHBV5_001194"
                     /pseudo
     CDS             complement(20202..20711)
                     /locus_tag="ACHBV5_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
     gene            21319..23652
                     /gene="hsdR"
                     /locus_tag="ACHBV5_001195"
     CDS             21319..23652
                     /gene="hsdR"
                     /locus_tag="ACHBV5_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HFM9966994.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            23665..25128
                     /locus_tag="ACHBV5_001196"
     CDS             23665..25128
                     /locus_tag="ACHBV5_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HFM9966995.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFKDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            25128..26696
                     /locus_tag="ACHBV5_001197"
     CDS             25128..26696
                     /locus_tag="ACHBV5_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFM9966996.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNS
                     YYGNKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTEIPWVSISDMP
                     ISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPATHNEAIISIF
                     PYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPISNHEEMKRIIF
                     KVDLLFQKVSQLFE"
     gene            complement(26650..>27195)
                     /locus_tag="ACHBV5_001198"
     CDS             complement(26650..>27195)
                     /locus_tag="ACHBV5_001198"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFM9966997.1"
                     /translation="IPMNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKP
                     LEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGF
                     IFQLTPFESSEIISKFLLFNLSSPLFYKQLKALTKLSGQALYNIPKTTLSELLIPLAP
                     FEEQELITQKVEKLFEKVNQL"
BASE COUNT         8959 a         5411 c         4816 g         8009 t
ORIGIN      
        1 agtaaccaaa atccgaccac atagccagcc cctatgaata tagccattaa agctagcatg
       61 gaatttagga aattaaaaac caccgcagat acaaaggtta gcacaaaaac attaaaagca
      121 atggtgtcag aagccaagac tagaatatag ggtgtcaacc gatctaaagt tttggaatct
      181 aggaaaaata agtgtttata catgatgacc tcctctatgg ctgaaaagca agccttttgt
      241 ttttttaccc caagacccta tgtagaaaag tgagcaaaaa cgggaaggtc gctacaatat
      301 tattgatcac atgcaccgca taggatggat aaatgctctt ggtatagcgg gtcaaaccag
      361 caaagatgat tccaactgtt gcaaagacga agatatctaa cagactaggc aggcttgaaa
      421 aatgagggag agcaaataaa atagaaggaa gaagcaaatc aagaccaaat cgcgaatgct
      481 taaagaaagc atgttgcagt aatcctctat aaatcaattc ttccatcagt ggaaccagaa
      541 agaacagggc tatataaata cctagctctg caaagttagt cccactataa ccaatcaata
      601 cagcccaacc ttccgcagtt gactgaacat gtttagctgt ctgaacgtta aaagagatct
      661 ggaacactac cactaatact gtcaaaatcg aataccaaag ccattttttt cttggaatgc
      721 ggaagagata accatggcct gtcttaacaa gaaccacaat catgactcca ataaaaagta
      781 aactcaagat attttgaatc cagaataaat tgcctatctg agaagaaaat tgccaatagt
      841 tttggacgat aagcgtcagc tgagaaagac caaatacgaa aaataagtaa gagaagactg
      901 cacttatttt gaatagaagt tgatactttt tcatagaaat cctccctact ataacctcac
      961 cttgtcaggc tctactgctg taagattaag aagacagttt gtttttttta aggctaacct
     1021 gactactaga taatagatac attaaggcat taaagacaat gaaaatatgt ccatagaata
     1081 aaatcaacct cgcatccaaa ccaagataaa gtttgattat caaaaagatg agcaaaagaa
     1141 tttgaaacca taaggttttt ccaaaaataa atttaaagcg atttcgaata tctacttcct
     1201 tgatttttac cgccacccct ttattagcaa gaaggaaaac tcctgcttca aacaaaccac
     1261 tgtaaagaac aagccaccca atagatacga tagagatttg taaaaatgtc cctaaaagaa
     1321 tatccaacac actactcaag aaaataacaa aaaataatct gtatttcata ttaaatacct
     1381 ccattcattt atttcactaa caatttaata gagccttcta ctcaaatatc ctgtcagaaa
     1441 aggatagaaa gctacttttt ataatacttc aagccccaca tgagcagaag cgtgataaac
     1501 aagcagagaa tacacctata taagcgatta gttgttgata gaattctgtt tctgaaatac
     1561 ctctatacaa acaaatgaca aacataaaat ctgccaagcc gataaacata agttgattgg
     1621 ttctaggact aaccaaatca tcatttactt atatttaaga gtatctcttt tatgttagtg
     1681 tatgttaaca ctaaaaaaca agttaggcca ataatattta aaatgaacaa taacggggtt
     1741 aagtctctaa aaaaattatc tactgacact acaagaaata ctatacatat tatagtcgaa
     1801 actatctttt tcttatccat aattatttac tcctttccta acaaatccaa cttatcaatc
     1861 aagagcgatt tttaacataa tgtagcagca cccgttgcaa ctttgacaag tttagtatat
     1921 cattgttttt taaaattttt catccaaatc ttgaattgtc atcgaaacct cctaaattgc
     1981 aaaaacttca ttagccccta ctttttataa tacttcaaac cccaaatgag tagaagcatg
     2041 atgatcaagc aaagaatagc accaatataa gcgattagtt gttgataaga ttctcctgct
     2101 gtgatacctc tatacaaaca aataatagac ataaagcctg tcaagccgat aaacatgagt
     2161 tgattggttc taggactaac caaatcatcg tcttcaaact cttttatccg catttcccta
     2221 gtgaggtaaa cagtgaccaa aatagaagct aagttaataa ccactaaaag aaattggaaa
     2281 actgacgaaa tagaaataga taagtagaaa caagcaaagg caactgcccc aggaacaatc
     2341 tcacaaagaa tatgattctt tttaatcaag aaaatctttc atttcttttc tttcttttta
     2401 attaaagaaa aatagatcat aaccgcaatc atataggcta tggtataaaa tagattatac
     2461 caaatactct ccctaagcgg ataaagaaag atggacatga tcagatacag aacgaaaata
     2521 atcagtattt ttttcttcat aagatttcct cctaaatgtg cgatttatct tagttgagca
     2581 agaacattta cactgctagt atagcactta ttttgacctt ggatcactca aatcataaat
     2641 ggtcatcaaa acctcttgaa ttgtaaaaat taaaaaaagc aagcatgaaa aacatacttt
     2701 cctctttatg ttgtattgat accaacttgt ttgtagactt ttcatcctgc tatcacatat
     2761 cattttgaca ggcgaaacaa tattaaagaa actcccctgt aaattaagct agcaaataca
     2821 ggggagaaat ttatttttta gagagtacta tccgtatcct ttttggaaga ttttgaaaat
     2881 atttttctaa ttaagtcatc catataagga ccaaatatac caactactaa accaataata
     2941 aaacttttaa aatccataat taccaccaac atgttgctac ataggctaca cctccaagta
     3001 tagctccacc tgcagcacca gttacaccta ttcctatagc aaatggtccc aatagaaatg
     3061 tcaaaccgtt gttgcacacc catcaattgc gccatatgca acccctgctg cacaactaat
     3121 ttttcttccc caatcaatat ctccaccttc aacgcaagca agcatttcat tatccataac
     3181 agaaaattgt gacatcattt ttgtattcat atagtatgtc acttttcagt tacggaacaa
     3241 gtttaatata aaaattatca aaaaaacata ggcaataaag agaaaaatta atttatcata
     3301 gattagaaat aatatgacaa aacaattcaa tgatgttaat tcaatagtct tttgtttttt
     3361 atcagagata cttatggata gataaataag ataggtttga aaagcgaaga gaataataaa
     3421 gaatatagcc ttcataaaat ttagctttca tttttatgat gtagcggtat aggctaaata
     3481 tccacaaacc actgctcctc caattcctcc tattgcagcg ccccatggtc ctagaatttt
     3541 cccatatttc actccacccg ctgcacaacc taaagcagca actacagctg ctcctccgga
     3601 attacctcca taaacctcac tcagcattgt ttcatttata ttacaataag tattcataca
     3661 agtctccttt tattaaaatc cacccgttgc ccctgttact cctgcccaaa gatccacacc
     3721 aaatttagct cctatgtatc cacatgctcc cataaatggt gctccaacac cactcgcagc
     3781 acaaatagct gtccctagcc cccagccacc aaaagcagca ccaccacctt ctaagacatt
     3841 agtttgccaa ttattcttgc ctccttcaat actagataac atagttatat ccatttcatg
     3901 aaattgttcc atcatttttg tattcatgac aaatactctt ttttattttt aatttttgtc
     3961 ttgttgtaac tttgacaagt ttagtatatc atcgtttttt aaaatttttc atccagatct
     4021 tgaatagtca tcgaaacgtc ttgaattagc ttttcatttg aaaccacctc taaatttttt
     4081 aaaaaaagat aatttctaat tattttttac cattcaggaa gtttcaatga ctattcaaga
     4141 tttaataaaa tatgaactta tttttatggc ataatatacc tatctactat atgaaaggaa
     4201 ttgccaatga cttcttataa acgtacattt gttcctcaaa tagatgcgag agactgcggt
     4261 gttgctgcct tagcctcgat tgctaaattc tatggttcag atttttctct agctcacttg
     4321 agagaacttg caaagaccaa taaagaaggg acgactgctc ttggcattgt aaaagccgct
     4381 gatgaaatgg gctttgaaac aagacctgtt caagcagata aaacgctctt tgacatgagt
     4441 gatgtcccct atccatttat cgttcacgtt aacaaagaag gaaaactcca acattactat
     4501 gttgtctatc aaacaaagaa agactatctg attattggtg atcctgaccc ttctgtaaaa
     4561 atcactaaaa tgtcaaaaga acgctttttc tctgaatgga ctggagtagc tatttttcta
     4621 gctcccaaac ccagctatca accccataaa gataaaaaga atggtctact aagcttcctt
     4681 cctctgattt tcaaacaaaa atctctcatt gcttacattg ttctctcaag cttattggtc
     4741 actattatca atatcggtgg ttcttattat ctccaaggaa tcttagatga atacatccca
     4801 aatcagatga aatcaacttt aggaatcatc tcagttggtc tggttatcac ctatatcctc
     4861 caacaagtca tgagcttctc cagagattaa gcattgatgt gattttatcc tatattcgcc
     4921 atatttttga acttcccatg tctttctttg cgacacgtcg tacaggagaa atcatttcac
     4981 ggttcacaga tgctaactct attatagatg ccttggcttc taccattctt tctctttttc
     5041 tggatgtttc tattctgatt cttgtagggg gcgtcttact ggcacaaaac cctaatctct
     5101 tcctcctttc tcttctttcc attcctatat acatgttcat catcttttct tttatgaaac
     5161 ctttcgaaaa aatgaaccat gatgtcatgc aaagtaattc tatggttagc tctgccatta
     5221 tcgaagatat caacgggatt gaaactataa agtcgctcac gagtgaagaa aatcgctatc
     5281 aaaatataga cagcgaattt gtagattatt tggaaaaatc ctttaagctc agtaaatatt
     5341 ctattttaca aacgagttta aagcagggaa caaaattagt tctgaatatc cttatcctat
     5401 ggtttggcgc tcaattagtc atgtcaagta aaatttctat cggtcagctg attaccttta
     5461 acacactttt ttcttacttt acaactccta tggaaaatat tatcaacctc caaaccaaac
     5521 tccaatctgc gaaggtcgct aataaccgtt tgaacgaagt ctatctagtc gaatctgaat
     5581 ttcaagttca agaaaaccct gttcattcac attttttgat gggcgatatt gaatttgatg
     5641 acctttctta taagtatggt tttggacgag ataccttaac agatattaat ctcacgatta
     5701 aacaaggaga taaggttagc ctagttggag ttagtggttc tggtaaaaca actttagcca
     5761 aaatgattgt caatttcttt gaaccctaca aagggcatat ttccatcaat catcaggata
     5821 ttaaaaacat tgataaaaaa gtcttgcgcc gtcatattaa ttacctaccc caacaagcct
     5881 atatctttaa tggctctatt ttggaaaact taaccttggg cggtaatcat atgattagtc
     5941 aagaagatat tctaaaagct tgtgaagtag ctgaaatccg tcaagacatt gaaagaatgc
     6001 ctatgggcta tcaaactcag ctctctgatg gagctggtct atcaggagga cagaagcaac
     6061 gaatcgctct cgctcgtgct cttttaacta aatctcctgt tttaatacta gatgaagcta
     6121 ctagcggtct tgatgtcttg actgagaaaa aagttataga taatcttatg tccctaactg
     6181 ataaaaccat tctctttgta gcccatcgtc tcagtatagc cgaacgaacc aaccgtgtca
     6241 ttgttcttga ccaggggaaa atcattgaag ttggtagcca ccaagagtta atgcaggcgc
     6301 aaggtttcta ccatcatcta ttcaataaat aaggagaatg tcatgaatcc taatcttttt
     6361 agaagcgtcg agttttatca gagacgttac cataactatg cgacagtgtt aattatacct
     6421 ctttcattac tatttacttt catcttgatt ttctcccttg ttgccacaaa agaaattact
     6481 gtcacttccc aaggagaaat cgcccctaca agtgtcattt catctattca gtcaaccagt
     6541 gataatccta tccttgctaa tcatttagtg gcaaatcaag tagttgaaaa aggggactta
     6601 ctcatcaaat actctgaaac aatggaagaa agtcagaaaa ctgccttaac aactcaatta
     6661 caaagacttg agaagcaaaa agaaggactt ggaattttca aacaaagctt agaaaaagcg
     6721 actgatcttt tttctggcga ggatgaattt ggctaccata atacctttat gaattttact
     6781 aaacaatccc atgatattga actgggtatc tcaaagacta acactgaagt ttcaaatcaa
     6841 gctaatctta ccaatagcag ttcatcagcc atcgaacaag aaattacaaa agttcaacaa
     6901 caaattggag aatatcaaga gctgagagat gctatcgtaa ataaaagagc tcgcttacca
     6961 actggcaatc cgcaccagtc aattttaaat cgttatctta tagcctctca agaacaaaca
     7021 caaggaacgg cagaggagcc atttttatct caaattaatc aaagtattgc aggtctggaa
     7081 tcatctatcg caagcctcaa aattcagcaa gctggtatcg gaagtgtagc aacttatgat
     7141 aatagtttag caaccaaaat tgaagtactc cgcactcagt ttttacaaac agcctcacag
     7201 caacaactaa ccgtggagaa tcaattaaca gaattaaaag tacaactaga tcaagcgaca
     7261 cagcgcttag aaaataatac cttaaccgct ccaagtaaag gtatcgttca tctgaacagc
     7321 gaatttgaag gtaaaaatag aattccaact ggtacagaaa ttgctcaaat attccctgtc
     7381 atcacagata caagagaagt actaatcact tactacgtat cttctgacta tctacctcta
     7441 ctagataaag gacaaactgt aagattaaaa ctggagaaga ttggaaatca cggcaccacc
     7501 atcatcggcc aacttcagac aattgatcaa actcctacca gaacagagca aggaaatctc
     7561 tttaaattaa ccgctcttgc aaaactatct aacgaggata gtaaactcat ccaatatggc
     7621 ttacaaggtc gcgtcactag tgtaactaca aagaaaacat attttgatta tttcaaagat
     7681 aaaattttaa cccattctga ttaattttca gataacactc tataactatt tattatctta
     7741 tcaaaaagga gaatcataac atggataaga aacaaaacct aacttcattt caagaactaa
     7801 caactaccga actcaaccaa attataggtg gaggatggtg ggaagatttc ttatatagat
     7861 ttaatataat tgaacaaaaa aatacaaaag gatttcatca gccaatacaa ctataaaaaa
     7921 acaagaccaa gagaacgcac tctcggtctt attttttctt cattctatat gtattacagt
     7981 aagtacctga cgaaaaacgt gatcttggca ggtggtattg agactggtat tgggatgact
     8041 ttccacaatt ttcataacgg tatagagacc aactcctctc tcctcccctt tagaacttgc
     8101 tccaaaggag aagatttcag aaatatcgat tccctcttct ttgatggaat tttcaatgat
     8161 aaaggtctcc tgtgctccat ttttaaaaaa ggcaattgaa acatgaggtt gacaggcttc
     8221 tacactagct tcaatagcgt tgtcacaaag gatagacaca acggttagaa aatcaagtag
     8281 actcatcccc tctacctgaa tctcctctgg aacttcgaca ttaaagacaa tgttcttatc
     8341 tctagctttt ataaattttc cagctaggag acttttgagg gcacgatccc gaacattcac
     8401 caatcggcca aggtcatatt tattgtcctg caatttctga ctggaatccc ttaagaccga
     8461 gtcgtagatc tcttttatct gctccatatc ctcctcttca atgcccaaac gtaagctggt
     8521 taagaggtta gtgtagtcat ggcgaaaact ccgaatttcc ttgtaaagtt cctctatatg
     8581 ccgactatag cgttccatat ctctgtagcg caaggtctgc tcttggttca gttcctcctg
     8641 aagtttttcc ttcaaatagg tatccaattt cttgataccc cccataaaaa agagtaggta
     8701 aaacactagg atgagatggc gaacagtcgt tgattgaata ccttgttcat attcaaggta
     8761 agatagactt tgcatcacta gataataagc ccccattgcc cagttaatct tagtaagaga
     8821 cttttgaaaa cctgtatcta gaaactccct tctcaatcta gtgaaatcat agtctaacca
     8881 tttcaaaaag actaaaacta tgaagcaaac gaatatcata atcaataaaa agataggatt
     8941 gccatcccca tctacaattc cttgccccaa aaatggaagc acaaaatagg aaacacctct
     9001 gtaaaagagc tctactaata tcattgggaa gagaccataa aaaataagga tttttttagg
     9061 aagccctctt aacaataaga aagatagacc tataccgaac aaaggttcta taaaatagga
     9121 caaatattta cttacagcca aaaattgaaa agtcgtaaaa atgatcccta gaagaaattt
     9181 cagaagaaag gccttaaaaa tcctctcgaa agtaagatca attccatcca ccttaaagaa
     9241 gatgacaatt tctagtccat tagtaacaag tgtatacaac aatatccaag caatgttcat
     9301 aaattctcct agctcagtgt aatttattga tggcctcaga cacttccctg accttataac
     9361 gggcgattag acaacttcca ccattgggaa agaaaagcag tttttctttc ttatccaaat
     9421 gcaccacatt tgcaggattg atgagaaaag agcggtggca ctgcaagaga cggggctcct
     9481 gcttgaaaac ctcctctaaa ctcgctgtaa attccagcct gtctgtcttg gtatagagaa
     9541 taacacgatg ggctctgggc gacgtttcga gatagtaaac ctctttaaaa ggatactgaa
     9601 attgggcaaa ttttgattta aagtaaaagc aatcttccgc cagactttta ctatcttgac
     9661 tattggcata gaggagggct gtctcgatcc gagattcaaa ctcctctgct gacaaggcct
     9721 tatcaatgta gtccaaagca gacacttggt agcgaaaaga caggggcata aactccgagt
     9781 gagtcgtcac aaagacaatc agggcataag gatcccgatc ccgaatcttt ctagccactt
     9841 ccagtccctt catctcttca tttcgaatct caatatccaa aaagaatagc tgatgggccc
     9901 ccttctcatg cacttcagcc agcagttggt ccggcttgcc aaatacctca aaagagctag
     9961 gaatgatatg atgtgctttc aaaagtttct caatcgtcgt ttcaattcta gtctgttggg
    10021 aaaaatcatc ctctaaaaca aatattctca tcttcttact ctccctcttt caaccatttt
    10081 tgacgaattt ctctatagcg acgtctggca tacttgacag cgtattgacc ttcttctccg
    10141 agaaaaagga ttctttcttg aaaatcaatc gattttaatt tatcaagatt aaccaaacaa
    10201 tttcgatgac atctcatcaa ggtttcccca cattggttct caagattact taaattttga
    10261 agcatattaa aactagcttc ttctgtaaca atctgtacgg tatgggcttt agttggatgt
    10321 gtttggatat agtagatatc gtcgatgttt actttataga ctgttttctg cgtctgaata
    10381 atcatatatt tcattggatt ctcctcctaa gaaaagaata acagaaaagg tctagcccaa
    10441 gcacacccaa tcctaaacag tctttgaaaa ctcctaaaag gattattttc tacaacatca
    10501 tgatgagctt acaactattt tatcataaaa ttcactcagc gcaattcaag acatttcaat
    10561 gacaattaaa gatttgaata aaaaaaaaga attaaaagtg ataaactaac agtatcaaaa
    10621 cacagttgcc agaagtaaga ctggcaccca gattaaagga ggcattccca tgacagatac
    10681 agaccccatc aaaagagctc atactttgat tactgactta aacaaagcct accaagcatg
    10741 caaacaggca agcgctgacg acgtccgctt tcaggagcaa ttaaactcta ttcttggttt
    10801 tctagccaag gctgaaacag tggataatcg attcttgatt gaactagaaa aattttacca
    10861 gacttccagt cttctcatgg gactcagcgc tcttgatcca gatgctccaa ctcgcgccgc
    10921 ttggcgggcc tatgaccgct tccactttga ccaagtcaag accaagttaa tactcaatga
    10981 aaatcaaaga gcaaactagg aagctagccg caagctgtac ttgagtacgg taagacgacg
    11041 ctgacgtggt ttgaagagat tttcgaagag tataagtctc tacggaccaa ccattatcct
    11101 gtagtaacaa aaaagaagtt gagacagact gaactcaact tcttttttag tgtcgtatca
    11161 gcaatgttag tcctgcatct gacgttttac ctgataaggc aaatacaaga ctagtaaaac
    11221 caaaccagct cctagtaagg ctagaagggc tagtttttct tggaaggtaa tcaacccaac
    11281 aactaattcc acaagtaaaa caaaactggt caatcctcga actacctcct gtaagccttt
    11341 ttccttttgc cccttgtcca gcggaaagag ttgggtcaaa tactggtagt caaaggcatg
    11401 atagagggcc agcaactgga agagcaagag gtagttaaag agaactacca ctgctgtcgc
    11461 aatccaagct tgctcgataa aaacctgcgc cagtacggaa agtaagagaa gacgaagact
    11521 gagagcaaag aggtcgccat ttcgcagata agaacgcaga tagagatttt gccaaatctt
    11581 cccaggcacc ttctgaacag cctttaagat aaagtccaga taggcacgac gcttaacgct
    11641 gtttgaaatt cccttgacct gcgtaaagag ggcaaagaaa cgaagcaaga cttgcttacg
    11701 cttgctttct tgggaaatga catagtccca gtccagccca gtttcagtga aaaatttgct
    11761 ggccttttga cgaaagtgga aatattttcc tacccccaat aaaagcacat agagcagaaa
    11821 aactggcaag ccataaccca ttgctaaaaa taaaggcgca aataacagca agaaaagggt
    11881 ctgtacaaag agccaaaaga ctagggaaat gccagtttga cgcttgagat ggagcttgat
    11941 ttcctcttct ccaactaaga gaaagagctt gtctggagcc tccatatagg tggcaattcc
    12001 tccccaaagt aaaagtaaaa cagacgtaat tcctacaaac aaaaggatag gccaatgatt
    12061 ttcaggaaaa tgttgtaaga gttgactgta ctggtaggct agaaagccca acaggacaag
    12121 caggaacaag acaaagtggt cattgagcac atagcgcaga taaccaagac actccttacg
    12181 aaaggcctgc tttctcttta aaaacaagtc tttcatagat cctcctcttt ggtcagagcc
    12241 aagtaaatat cattcaaact agcctcaggc atatcaaagg cttcacgtag ttgcaggaga
    12301 ttgcctttgg cacgcacctc tcccttgtga agaatgacaa aggcatcaca catcttctcc
    12361 gccgaatcca gcacgtgggt actcatgaga atagacttgc ccttttgctt ctccacttcc
    12421 aaaagctgaa tcaaatcaga aatagccagc ggatcaagac caaggaaagg ctcatccacg
    12481 atgaaaagac ttggatccac cacaaaagca cagataatca tgaccttctg cttcatccct
    12541 tttgaaaaat gaacagggaa ccagtctaat ttctgttcca aacggaacat ttttaacaag
    12601 ggctctactc gttcgaaagc cactttttgc tcaataccgt aagccatagc aaccgtttcg
    12661 atatgctctc tgagggtcaa ttcctcatac agactaggcg tctcaggaat gtagccaatc
    12721 tgcttgcggt agctagtcgc atctccttgc agagtcaggc cattgatatt gatggagcca
    12781 ctataaggtg ccaacagacc gataatctca ttgatcgtcg ttgatttccc agcaccattg
    12841 agaccaatca aaccgaccaa ctgcccactt tcaacagtaa aggacacatc tttcaaaaca
    12901 ggaacatgaa catagccacc tgtcaggttt ttaatttcta acatattttc tccaaatctg
    12961 gtataatgta gctatattat atcaaaattc agtacagtag aggtagattt tatgtcagat
    13021 tgcatttttt gtaaaatcat cgcaggggaa attcctgctt caaaagtata tgaagatgag
    13081 caggtccttg cctttcttga tatctctcaa gtaacactag gacacacctt ggtcgtgcca
    13141 aaagaacact atcgcaatct tttggagatg gatgctacga gcgccagcca actctttgcc
    13201 caagtaccaa aagtagctca aaaagtcatg aaagtcacta aggctgctgg tatgaatatc
    13261 atttccaact gtgaagaagt cgctggtcaa acagtttttc atactcacgt tcaccttgtg
    13321 cctcgctaca gtgctgacga tgacctcaag attgatttta tcgcccacga accagacttt
    13381 gacaaacttg ctcaagtcgc tgaaaccatc aaaaacgctt aaggagttgc tatgaaatta
    13441 tccaacctac tgctatttgc aggagctgca gccggaagtt atctggttac aaaaaatcgc
    13501 caaaccatca cagatgaagt cttgaatacc actgaccgcg ttcaagctat caaggacgat
    13561 gtggatatta tccaaaacag cctgcaaatc attaaccagc aaaaagaact tatcaaggaa
    13621 taccaagaag acttgactta caagtttaag gtcttggaaa aggatatcca gactagacta
    13681 gctgtgataa aagaaatgca gggaactgaa gataagtaaa aagagcccga cggctctttt
    13741 ttaaaacgta aacaagttat agtgaattga atttagaata gcacatcata gtttctaaag
    13801 cattgttaga gattacttta aaatcctctt atcaatttgt tcatattcta tttcaatcta
    13861 ctatatatat cccatcaact atgcatcata atttaggtaa ctcatactca ataaaaatca
    13921 aaaagcaaac tagaaagcta ggcacagact gctcaaaaca ccgttttaag gttgtggata
    13981 gaactgacga agtcagctca aaacactgtt ttgaggttgt ggatagaact gacgaagtca
    14041 gtaaccatac ccatgacaag ccgacgctga cgtggtttga agaaattttt gaagagtatc
    14101 attcaccatt tcacaactaa atcgaagact ttctgccgta atgaaaacac ctgaaacagc
    14161 ttggtttcag ctgtccggaa actttaagac ttaggttcaa agtttaggta tggaacttcg
    14221 aaggaggtcg ctaccgtccg tcattactta ggaaagtctt aaaaaatcta taaagtaaaa
    14281 agagcccgac agctcttttt gtttatactc aatgaaaatc aaaaagcaaa ctaggaaact
    14341 agccacgggc tgctcaaaac actgttttga ggttgtagat acgactcaca tatatacggc
    14401 aaggcaacgc tgacgtggtt tgaagagatt ttcgaagagt attattctcc atcaaaggca
    14461 tcttttatat ggtcaaagaa gccttttttc tttggattta ctttcaagtc accagcagtc
    14521 gcgaattctt tcaaggctac tttttggcgg tcgttcaagc ctgtcggtgt tacgacatta
    14581 acagtaacgt attggtcacc aactgcaccg ccacgaaggc tcggtgcccc cttactacgt
    14641 aggcggaatt tcttaccagt ctgagttccc tctggaataa ccaattcaac atcaccgtga
    14701 acagttggaa tatctactgt atcaccaaga gccgcttgga caaagttgag gttgagattg
    14761 tagaagatag tcgttccttc acgttcaaac ttgtcgctag cttctacaga aactactaca
    14821 tacaagtcac cataaggtcc accgttaaag cctgcttcac cttgaccagc gaggcgaatt
    14881 tgttgacctg tttccacacc agcagggatt ttcacatgta cgctatgagc ttgtttctca
    14941 tgacctgttc catgacaggt tgtacatgga tatttgattt cttttcctcg accgtgacag
    15001 acatcacagg ttacttggcg acgcatcata ccaagaggag tctgcgtatc gacgttaatg
    15061 acaccagcgc catgacagcg tccacaagtg actggacttg tccctggctt agcaccagag
    15121 ccattacatg tacgacagcc agcttcacga tgatacttaa cttccttctc agttccgaag
    15181 atagcttctt caaaggtcaa attgacacga tactggagat catctccttg gcgaggagcg
    15241 tttggattgc gcgaagaacc gcctccgccg aagaaacttg agaaaatatc ctcaaaacca
    15301 ccgaagccac ctgccccatt gaaaccaccg aaaccaccag ctccaccaaa accaccattg
    15361 gcgcctgcag caccatactg gtcataggca gcacgttttt ggtcgtcact caaagtctca
    15421 taggcttctt gaacttcctt gtacttgtcc tcagcaccag gctccttgtt gatatctggg
    15481 tgatattttt tggaaagctt acgataagcc tttttgattt cgtctgccga agcgtttttg
    15541 gataccccca gacgatcata aaattcagta ttgttcatac aagataccaa gaccgtaaaa
    15601 ttcgactgaa aaataggaaa tctgacgctg gagcgacgct cctagacaga tttctctttt
    15661 ttccgagaat ttaggtcggg ttcaattcct ttcttttata ttgatgagat aatactccag
    15721 ccactcggcc ctatcccttt ttaccgaaaa acagaggctg ggttgcaacc tctgtggtta
    15781 gattattcat ttgaaataaa aatggttgta ttatctctag tagtaatctt caaagacctt
    15841 ttagctaaat caaactcaaa tttattatag tgtgggtctt gtgttttata taggtgtaac
    15901 tcctgacata tatgatccga aaagtaaatc ataacatctt taaacacaga agtgtggtca
    15961 tatttactct taccaacagc tacttctgta aattctttat aaatgacatt tccatttctt
    16021 tccacagtca ccagcatttc tgttggatta taatccaaat taaataatta ttcaaaaaaa
    16081 ctttatcttt tcatgataat ctgcaatgtc agaaagatta tttttattaa cactcataac
    16141 actagcccct tatttttcag taaactctcc gtctacgacg tcatcgcctg cgtttcctgt
    16201 tgcttgtgcg ccttctgctc cttcttgagc ttgttgcgct gctgcggctt gttcgtagag
    16261 tttcacagca aggccttgag ctttttcgtt caacgcttca agtttcgctt tcatgtcgtc
    16321 caagttgttg tcttcttgag ctttcttaag gtcatcaagg gcagcttggg cagcgtcacg
    16381 ttctgcgtcg aagcctttac cttcagtttc cttgattgtc ttttcagtcg caaagattgc
    16441 ttggtctact tcattacgaa ggtctacttc ttctttacgt ttcttatcgg cttcagcgtt
    16501 tgcttctgca tctttcatca tgcggtcgat ttcttcgtca gtcaaatctg agttcgattg
    16561 gatgacaata gtttgttctt tttgagttcc aaggtctttg gccttaacag acacgatacc
    16621 gttcttgtcg atgtcaaatg ttacttcgat ttgaggaatt ccacgaggtg cagctgggat
    16681 atcagtcaat tggaagcgtc caagagtctt gttatctgct gccattgggc gttcaccttg
    16741 aagaacgtgg atatcaacgg ctggttggtt gtctgctgct gttgagaaga cttgtgattt
    16801 agatgttggg attgtagtgt tgcgatcgat aagttttgta aatactccac ccattgtttc
    16861 gataccaagt gacaatggcg ttacatcaag aaggacaacg tccttgacat caccagtaat
    16921 cacaccacct tggatagccg cacccatagc aactacttca tcagggttta ctgatttgtt
    16981 tggttcttta ccagtttcag ctttaacagc ttcaacaacg gcagggatac gagttgaacc
    17041 accaacaagg ataacttcgt cgatttctga caagctcaaa cctgcatctg aaagggcttg
    17101 acgaactgga acttttgtac gttcaacaag gtcacgagtc aaatcatcaa atttcgcacg
    17161 agtcaaagtc atttccaagt gaagaggtcc agcctcacct gcagtgataa atggcaagct
    17221 gatttgtgtt gaagttacac cagaaaggtc tttcttcgct ttttcagccg catctttcaa
    17281 acgttgcatt gacatcttgt cagtagacaa gtcgataccg ttttctttct tgaattctgc
    17341 taccaagtgg tcaatgattt tttggtcaaa gtcgtcacca ccaagtttgt tgtcccctgc
    17401 agttgacaat acgtcgaaga caccgtcacc caattcaagg atagagacgt cgaatgtacc
    17461 accaccaagg tcaaatacca agattttttc ttctttgtca gtcttgtcca aaccataagc
    17521 aagagctgct gcagttggtt cgttaacaat acgttctact tcaagaccag caattttacc
    17581 agcatctttt gttgcttgac gttgagcgtc gttgaagtaa gccggaactg tgataacagc
    17641 tttggttact ttctcaccaa ggtagtcttc agcgtagcct ttcaagtatt gaaggatcat
    17701 agctgagatt tcttgtggag tgtattcttt tccatttgca gaaacttttt cagaagttcc
    17761 catcttagat ttgatagaga taactgtatc tgggtttgtg actgcttgac gttttgcagc
    17821 atcaccaacg atgatttctc cgtttttgaa tgagactaca gatggagttg tgcggtttcc
    17881 ttctgggttt gcgatgattt tgctttcagt tccttcaaga actgcaactg ctgagtttgt
    17941 tgtacctaag tcaataccga taattttaga catgtgtttt tctccttgtt agttaatttt
    18001 ctatttttct ttttgatact cttcttaagt ggcgacgccg tcagagcttg acttcgtcaa
    18061 tctctttgac taaactttga gcctaaggtc tcaaaatttg cgcaaatagc accacggcga
    18121 agagtatcgt ctttggttcg cttcgctcac tattacaaag ccaaacatat tttatctttc
    18181 ttcatagttt attgtcgttt cggacaagtt ttctattatg taaattgcga cacgaggagt
    18241 cgaaatcgat tttatttcga cgacgagtta gtaaggaagc taggcaaacg tcatagcgat
    18301 tgccgttttc tgacgagttg ctttagctac cgtcagaatt gccgaatcga acacgcccta
    18361 agctctgagt aaaaaagata gattttcttg tgttcatcga acacttcgtc aatctcctat
    18421 ttttactgcg agctttttac gagctttgta tcttagttat acaccactac cattgctggg
    18481 cgtaggatgc ggtcatggag tttgtagcct ttttgaaaga cttgggcgat ggtatctact
    18541 gggtgttcat cgtctgctgg gagagtttgg atggccatat ggtagttatg gtcaaattcg
    18601 ccatctgctg cgatttcttc aattccttct tctttcaaag cgtgaatcaa gctttcttgc
    18661 accatcgcca agcccttctt cacatcatct gtcaaacctt caactgcaag tgcacgctca
    18721 aggttgtcaa gagatggtaa gattgctttt gccaagtcct ggctacgata acgttgcaag
    18781 ttttgacgtt cttcattggc acggcgttgg atattttgca tttctgcatg agcgcgaaga
    18841 tatttgtttt cgaactcatc tgcacgttca tttgccaagt ccaactcaga cttttcagga
    18901 gttgtttctt cagctgtttc cacaacttcc tcttcttgaa cttcttctac ttcttcattt
    18961 tttatatctt gggccatgtt cgcctccttt aatgatttca atcttaatgt acttcgtaat
    19021 gattactgct gaggtagcgg taaaaatctg tcaacttcat ggtcaaaaca cggttgacca
    19081 cattgacttg attgattagc tgttggtaat ccagattaac tggaccgata atggctagaa
    19141 ttccaactcc tcgataagga atgaggaact tactactaat caccgctagg tcagctaaac
    19201 aggactcttg accgtctgca acacgaacat tttgcatctg atcctcacgc aacccctcac
    19261 gaatctccaa ggccaccttt tgcggttggt caaagaactg ataggcttct agattggcaa
    19321 aattcaagag attgaccttg cccgccatca caatgttttc gttgaacatt tccttaaaga
    19381 tgtgttcaaa gagatcgatg acattatccg ttgttgtaaa gtaacgctgg ataatctgcg
    19441 gaatctccgt ccgaatcttg tagtgaatat ctaaaacggt gtgaccgagg aaacgttcct
    19501 gaatgatgct cttcagtttc agcaaatcct cctgcaagaa gttccttgga atcagaaact
    19561 gactagtaac cgttcgcgac tcgtctaggg taaataccgc caaggctgta tgttgcccca
    19621 aaacaacgat atcaaaggct gtcaaacgtt gcctgctcgg ctcaacatcc agtgccacta
    19681 ccgtacagcc actcaggtct gttagcaagt tagcagcctc ttgcagaata tcctccaatt
    19741 tgaagaattc ctgatcaaag gctttgacaa tctcatatac ctcattttca gccagccggt
    19801 gaaaatccag tgagtgtttc acatagtact gaaaaccagc aacacttggc atccgaccgc
    19861 ttgaagtatg agccttctca agcaaccctt gtttttctag ttccgccatg tcattacgaa
    19921 tggttgcact gctagagtta atagactctt gcaaggcttt tgatccgaca ggttcgtgcg
    19981 ttttggtaaa gatgtcaata atcagattta aaatatcctg ctgacgctct gtaaccatct
    20041 catcactcct ctctgtctga tcaattagca ctcaatgcat ccaagtgcta acttatgatt
    20101 ctattataca cccttaaaag agaatgtcaa gacaaaaact caaaaaatta gcactctttt
    20161 atcaagagtg ctaaaaatca atctgaagac ctagaacctt gctattcatc tactcgatat
    20221 ttccttttta gtctgaaata accatgaatt agataagaaa tcagaaaagc atataaaaca
    20281 aaaataagaa agaaagacat agaaagatcc tctctaaaca aactcgtaca aacaacaaga
    20341 ccacctaaga aagtagttgt acaggaacga agtctagatc gcataacttc ccatttgagc
    20401 cccttactca tatagacttg atcctctgga agtaaatcag aagacgattt acgaagaatc
    20461 gaacaagaac ctgctcctat caattcccaa cctctatctc taaaatcttg cagttcatgc
    20521 ttatattttt taagaaatct agaatcatag atacggtaga tgacatcgtc tggttgacat
    20581 tggtcaaaat agaacaaacc aaaacgactc gttctatacc tccaaccttt caaatgcatc
    20641 tcatgtaaat attcttctta cttgtccaaa tcaacaatgg tgaaaatccg aaattctact
    20701 ctgctattca ttgtcttacc ccaaaattag aaaacatgcc tggcgttatt tattagataa
    20761 ttctttccac ttttgactca atctccaaaa aatataagaa atctgaatcg caaaaactat
    20821 caataaaacc caatctatta tgaaaatcaa aaacactttc caactgaaag aactacctcc
    20881 agtgacaaac tttgagaaaa acggtagtag agctaaaaag agaagtaaaa taggaagcat
    20941 ccgcattgtt aaaatccgtt tggcataaaa aaatctttat ttaaactaaa atattatatc
    21001 aaaatttacg ccagtttttg aacggctgat gtagatattt tatactttca aaatgtttaa
    21061 atgtgattat ttatttttga aaaatagctc accagcccga ctgaaagtgc ttatagaatg
    21121 ataataagtc gcctgccgaa aacagcggaa aatagcggtg ttatgcggag ataatctgac
    21181 gcgatgcgaa agtatattgc atacttattt tcaacaattt agcagagtat ttttataagt
    21241 gtgatataat agaagtataa tttgttctga tagtttattt tatggagaag tagattttta
    21301 gaatgcggag ggttcaatat ggttgagttt ataaagtcta agaaagaaat gagtgaggag
    21361 gatattaaag caaatttcat cactcctgct attgtatcca aaggatggaa aaatggtgag
    21421 catatcgctt acgaagaata cttcactgat ggtcgaattg aggttagagg agataaggct
    21481 cgtcgtaaag aaggaaaaaa atcagactat tcactgtatt accaatttgg aactcgaatt
    21541 gcaattgttg aggcaaagga taataaacac agcgttcgag caggattaca acaagctatt
    21601 gaatatggag agattttaga tgttccattt gtttattctt cgaatggtga tggctttatt
    21661 gaacacgacc gtatcacgag agaagaacgt gagctggagt tagacgaatt ccctactcgt
    21721 gaagaattat tttctcgtat gacgaaggaa aaaggattga cgtacgaaat tacagaagct
    21781 atctcaactc catactatac agacgccttc tcaatgaaaa cgccacgcta ttatcagcaa
    21841 atagctatca accgtactat tgaaacagtt gccagaggac aaaaacgagt aatgtttgtg
    21901 atggcaacag gaacggggaa aacgttcatg gcttttcaaa ttattcatcg ccttcgaaaa
    21961 gctggtttgg ctaaacgagt tttattctta gcggatagaa acatcttagt agaccaaacg
    22021 atggctgaag actttaggcc attcgaaaag gtaatgacga aaattacacc aaaacttttg
    22081 actgctcctg aaaaattaaa ttcttttgaa atttatctag ggctttatca gcaactaact
    22141 ggtgaagatg gaactgaaac acattatcaa aaatttgaca aagacttctt tgatttaatc
    22201 gtaattgatg aagcgcaccg tggttcagct aaggaaaaca gtaactggcg taagataatt
    22261 gattatttca gttctgcgac acagattggg atgaccgcta ctcctaaaga aaccaagaat
    22321 gcttccaata cggaatactt tggtgagcca atctatactt atagtttaaa acagggaatc
    22381 gaggatggtt ttttggctcc atatcgtgtt atgagagtta atttagatgt agatgtggat
    22441 ggttatcgtc cagaaactgg aaaagttgat gctaacggac aattaataga agataggtac
    22501 tacggcagga aagattttga taaaaccatt gtcattgatg atagaacgca aagagttgcc
    22561 aagtttgttt ctgattatat gaagcaaaac aatgcacgat ttgataaaac aattgttttt
    22621 tgtgttgata ttgaccatgc cgagcgaatg cgtgctgcac ttgtaaaaga gaatctagac
    22681 ttagtccaag aagactatcg ttatgtcatg caagtaactg gtgacaacgc tgaaggaaaa
    22741 gctcaactgg ataactttat ggatgtcaat tctaattttc ccgctattgt aacaacgtct
    22801 aaattattaa cgacaggagt taatgctaaa acatgtcgtt tgattgtttt agactctaat
    22861 atccaatcca tgactgaatt taaacaaatt attggtcgtg gcacacgtct ttatcctcaa
    22921 aaggggaaag aattttttac gattattgat tttcgaaatg ttaccaattt gtttgctgac
    22981 cctgattttg atggtgatcc agtgaaggtg ctggaaacag gtgcgaaaac agtcagtggt
    23041 tctacgcccg gtttcgtaag tgaggaaggt gacccagtag aaaaatatat cgttacagac
    23101 aagcaggtta ccattcttaa ttctactgtt caagtattgg atgaaaacgg gaaactgatt
    23161 accgaaagcc tgaccgacta cactcggaag aatatcttag gtagctacgc cactttgaac
    23221 gattttatca cagtttggca tacggcggat aaaaagaagc ttatcttaga cgaactttat
    23281 aaaaaaggag tttatctaga tgctattcga gagtcggagg gaatatcaga acaagaaatc
    23341 gatgattttg atttactcct aaaacttgcc tatggtcaaa aagaattaac caaaacggaa
    23401 cgtatcaata agctcaaaca aagcggatat ttatataaat atagtgagga agcgcgtgct
    23461 gttttggaaa ttttactgaa caaatacatg gataaaggta ttggagaact cgaaagcatt
    23521 gaaacattaa aacttccaga atttcagata tatggtggaa ccttcaaaat catcaatact
    23581 tattttggag ataaaaaacg atatttacaa gcaattaaag aattggagca agagctattt
    23641 acagtagctt aatgaaagga aagtatgtca attacatcat ttgtaaaaag aattcaagat
    23701 atcactcgaa acgatgctgg tgttaatggt gatgctcaac gtattgagca aatgtcttgg
    23761 ttattattct taaaaattta tgatagccgt gaaatggttt gggaattaga agaagacgag
    23821 tatgagtcaa ttatcccaga ggaattaaaa tggcgaaatt gggctcatgc tcaaaatggg
    23881 gaacgggtat tgacaggcga tgaattactt gattttgtca ataacaagtt attcaaagag
    23941 ttgaaagagc ttgaaataac ttcaaatatg cctattcgaa aaacgattgt taaatcagct
    24001 tttaaagatg cgaacaacta tatgaaaaat ggcgtcttgt tacgccaagt catcaatgtt
    24061 attgatgaag ttgatttcaa tagccctgaa gatcgtcatt cgtttaatga tatttacgaa
    24121 aaaattctta aagatattca aaatgctggg aactcaggag aattttatac accacgtgca
    24181 gcgactgatt ttattgccga agttcttgac ccaaaacttg gagaatcaat ggcagacctt
    24241 gcttgcggaa caggaggctt cttgacttcg actctgaacc gtttaagtag tcaacgtaaa
    24301 actagtgaag ataccaaaaa atataataca gctgtttttg gtattgaaaa gaaagcattt
    24361 cctcatcttt tagcagttac aaatctgttt cttcacgaaa ttgatgaccc taaaattgtt
    24421 catggaaata ctttagagaa aaatgttcgt gaatatacgg atgatgaaaa atttgacatt
    24481 attatgatga atccaccttt tggagggtca gaattagaaa caataaaaaa taactttcca
    24541 gcagaattac ggagttctga aacagctgat ttatttatgg ctgtcattat gtatcgtttg
    24601 aaagaaaatg gtcgtgttgg agttatttta cctgatggtt ttctatttgg tgaaggtgta
    24661 aaaactcgct tgaaacaaaa actggtagat gagttcaact tgcatacgat tattaggttg
    24721 cctcatagtg tctttgcacc gtatacagga atccatacga acattctttt ctttgataaa
    24781 acaaagaaaa cagaagaaac ttggttttat cgtttagata tgccagatgg ttataaaaat
    24841 ttctcgaaaa ctaagccgat gaagtcagaa cacttcaatc ctgttcgtga ctggtgggaa
    24901 aatcgtgaag agattctgga aggtaagttc tacaaatcta aatcatttac acctagtgaa
    24961 ttggctgagt tgaattataa tttagaccag tgtggttttc caaaagagga agaggaaatc
    25021 ttaaatccct ttgagttgat tcagaattat caagcggaaa gagcaacttt aaatcataag
    25081 attgataatg tattagctga tattttgcag ttgttggagg acaaataatg acaccagaac
    25141 aacttaaggc aagtattctc caaagagcga tggaagggaa attagtgccg caaaatccca
    25201 atgacgaacc tgcaagtgaa ttattaaaga gaattaaagc tgaaaaagaa aaacttatca
    25261 gtgaaggaaa aatcaaacga gataaaaagg aaactgagat atttcgtggt gatgatggga
    25321 aacattatgg gaagtttgct gatggaagta ctcaagaaat tgatgttcct tatgatattc
    25381 ctgatacttg ggagtgggtg aggttttcta cattggttga aattgtcaga ggtggctctc
    25441 cacgaccaat caaagattat cttacttctg aagtagatgg aataaattgg ataaaaatag
    25501 gtgatactga aaagggtgaa aagtatataa ataatgttaa agaaaaaatc aaaaaatcag
    25561 ggcttaacaa aactagattt gtaaaaaaag gtacattttt gttaactaat tctatgagtt
    25621 ttggtagacc ttatattttg aatgttgatg gtgcaataca cgatggatgg ttggctattt
    25681 cgaactatga aaactcatta aataaagatt acctattcta tattctttca tcaaatgtag
    25741 tttattctca atttctatct ctaattagtg gagctgttgt gaaaaacttg aatagtgata
    25801 aagttgcttc tattcttatc cctctccccc cactatccga acaacaacgc ataatagaag
    25861 caatcgaatc agctttagaa aaagtagatg aatatgctga aagttataat agactagaac
    25921 agctagataa agaatttcca gataaactaa aaaaatctat tcttcaatat gctatgcaag
    25981 gaaaattagt tgaacaagac ccaaatgatg aatcagtcga agttttactt gaaaaaatac
    26041 gagcagaaaa acaaaaactc tttgaagaag gcaagattaa aaagaaagat ttggacattt
    26101 ctattgtttc ccaaggagat gataactctt attatgggaa caaagacgaa acaacctctt
    26161 atcctatata tgaaatccca gaagcatgga gatatattaa atttgctagc ctagttaact
    26221 tcagaatagg aaaaactcct ccacgcagtg aagctacttt ttggggaact gaaatacctt
    26281 gggtatctat atcagatatg cctatatctg gttatgtaac taatacgaga gaatctattt
    26341 ctaaattagc attaaaatca aagaaaatag acatttcacc taaaggaact ttattaatga
    26401 gttttaaatt atctattgga aaagttgcca tattggatat tcctgccact cataatgaag
    26461 ccattatatc gatattcccc tatgctaata aagaaaatat tatcagagat tacttaatga
    26521 tatttttgcc acttatctct actttaggtg attcaaaaga tgctatcaaa gggaaaacat
    26581 taaatagtac cagtatctcc gaattattaa tccctatttc taatcatgaa gagatgaaaa
    26641 gaatcatttt caaagttgat ttactttttc aaaaagtttc tcaacttttt gagtaataag
    26701 ttcctgttcc tcaaaaggag ctaacggaat taatagctcg ctcagtgtag ttttaggaat
    26761 attatataaa gcttgacctg atagtttagt taatgctttc aattgtttat aaaataacgg
    26821 agaggacaag ttaaataata gaaattttga aataatctct gaactttcga atggtgttaa
    26881 ttggaaaata aatccaccag ccacaacacc atcatagtct ttatcgattc ttgcaaactt
    26941 tccaatatgt tctaaagagg ttgatacagg tgttattagc tgattatgtt ttaaataaac
    27001 ttgctcagag gagatgaatt gtgtatcaat gtagtaatcg ttatccaaca gagaaaattc
    27061 taaaggctta atattaccac cacgtataat tctaacacct ttattattaa tgcttaaatc
    27121 gcccttcttg taagaaagac ctgtattcat tgaaaaaata tcttttattt ttataacaac
    27181 ccaattcata ggtat
//
LOCUS       DAYYYC010000026        26297 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.026, whole genome shotgun sequence.
ACCESSION   DAYYYC010000026 DAYYYC010000000
VERSION     DAYYYC010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.026"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..906
                     /gene="lytB"
                     /locus_tag="ACHBV5_001199"
     CDS             <1..906
                     /gene="lytB"
                     /locus_tag="ACHBV5_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HFM9966998.1"
                     /translation="YMAKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDS
                     DGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYES
                     DGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNY
                     SAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKD
                     KNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEY
                     ASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(967..2622)
                     /gene="pavA"
                     /locus_tag="ACHBV5_001200"
     CDS             complement(967..2622)
                     /gene="pavA"
                     /locus_tag="ACHBV5_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HFM9966999.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2727..3224
                     /gene="ybeY"
                     /locus_tag="ACHBV5_001201"
     CDS             2727..3224
                     /gene="ybeY"
                     /locus_tag="ACHBV5_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFM9967000.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLGYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3205..3600
                     /locus_tag="ACHBV5_001202"
     CDS             3205..3600
                     /locus_tag="ACHBV5_001202"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFM9967001.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3617..4516
                     /gene="era"
                     /locus_tag="ACHBV5_001203"
     CDS             3617..4516
                     /gene="era"
                     /locus_tag="ACHBV5_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFM9967002.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4565..5389
                     /gene="mutM"
                     /locus_tag="ACHBV5_001204"
     CDS             4565..5389
                     /gene="mutM"
                     /locus_tag="ACHBV5_001204"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFM9967003.1"
                     /translation="MPELPEVETVCRCLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5389..5994
                     /gene="coaE"
                     /locus_tag="ACHBV5_001205"
     CDS             5389..5994
                     /gene="coaE"
                     /locus_tag="ACHBV5_001205"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFM9967004.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5981..7180
                     /locus_tag="ACHBV5_001206"
     CDS             5981..7180
                     /locus_tag="ACHBV5_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFM9967005.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7180..7329
                     /gene="rpmG"
                     /locus_tag="ACHBV5_001207"
     CDS             7180..7329
                     /gene="rpmG"
                     /locus_tag="ACHBV5_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFM9967006.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7369..7602
                     /gene="secG"
                     /locus_tag="ACHBV5_001208"
     CDS             7369..7602
                     /gene="secG"
                     /locus_tag="ACHBV5_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFM9967007.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KVRGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7704..10058
                     /gene="rnr"
                     /locus_tag="ACHBV5_001209"
     CDS             7704..10058
                     /gene="rnr"
                     /locus_tag="ACHBV5_001209"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFM9967008.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAANYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10021..10488
                     /gene="smpB"
                     /locus_tag="ACHBV5_001210"
     CDS             10021..10488
                     /gene="smpB"
                     /locus_tag="ACHBV5_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFM9967009.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10504..11364
                     /gene="tehB"
                     /locus_tag="ACHBV5_001211"
     CDS             10504..11364
                     /gene="tehB"
                     /locus_tag="ACHBV5_001211"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HFM9967010.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11437..12390
                     /gene="coiA"
                     /locus_tag="ACHBV5_001212"
     CDS             11437..12390
                     /gene="coiA"
                     /locus_tag="ACHBV5_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HFM9967011.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12409..14211
                     /gene="pepF"
                     /locus_tag="ACHBV5_001213"
     CDS             12409..14211
                     /gene="pepF"
                     /locus_tag="ACHBV5_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFM9967012.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEVLKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14213..14926
                     /locus_tag="ACHBV5_001214"
     CDS             14213..14926
                     /locus_tag="ACHBV5_001214"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFM9967013.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELENFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            14993..15934
                     /gene="prsA"
                     /locus_tag="ACHBV5_001215"
     CDS             14993..15934
                     /gene="prsA"
                     /locus_tag="ACHBV5_001215"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HFM9967014.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFKKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16051..16392)
                     /locus_tag="ACHBV5_001216"
                     /pseudo
     CDS             complement(16051..16392)
                     /locus_tag="ACHBV5_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            16805..16900
                     /locus_tag="ACHBV5_001217"
                     /pseudo
     CDS             16805..16900
                     /locus_tag="ACHBV5_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(17153..17773)
                     /locus_tag="ACHBV5_001218"
     CDS             complement(17153..17773)
                     /locus_tag="ACHBV5_001218"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFM9967015.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(17773..18255)
                     /locus_tag="ACHBV5_001219"
     CDS             complement(17773..18255)
                     /locus_tag="ACHBV5_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFM9967016.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSADEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(18255..19097)
                     /locus_tag="ACHBV5_001220"
     CDS             complement(18255..19097)
                     /locus_tag="ACHBV5_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFM9967017.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(19192..19992)
                     /locus_tag="ACHBV5_001221"
     CDS             complement(19192..19992)
                     /locus_tag="ACHBV5_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HFM9967018.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            20136..21515
                     /gene="glmU"
                     /locus_tag="ACHBV5_001222"
     CDS             20136..21515
                     /gene="glmU"
                     /locus_tag="ACHBV5_001222"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFM9967019.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            21525..22070
                     /locus_tag="ACHBV5_001223"
     CDS             21525..22070
                     /locus_tag="ACHBV5_001223"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFM9967020.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            22082..22396
                     /gene="macP"
                     /locus_tag="ACHBV5_001224"
     CDS             22082..22396
                     /gene="macP"
                     /locus_tag="ACHBV5_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFM9967021.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAAIFLLILLVLAMK
                     LL"
     gene            22413..23105
                     /locus_tag="ACHBV5_001225"
     CDS             22413..23105
                     /locus_tag="ACHBV5_001225"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFM9967022.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            23182..23673
                     /gene="rocS"
                     /locus_tag="ACHBV5_001226"
     CDS             23182..23673
                     /gene="rocS"
                     /locus_tag="ACHBV5_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HFM9967023.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            23771..24361
                     /locus_tag="ACHBV5_001227"
     CDS             23771..24361
                     /locus_tag="ACHBV5_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFM9967024.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAD
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            24370..26133
                     /locus_tag="ACHBV5_001228"
     CDS             24370..26133
                     /locus_tag="ACHBV5_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFM9967025.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         7987 a         4777 c         5770 g         7763 t
ORIGIN      
        1 tacatggcga aaaatgagac agtagatggt tatcagcttg gaagcgatgg taaatggctt
       61 ggaggaaaag ctacaaatga aaatgctgct tactatcaag tagtgcctgt tacagccaat
      121 gtttatgatt cagatggtga aaagctttcc tatatatcgc aaggtagtgt cgtatggcta
      181 gataaggata gaaaaagtga tgacaagcgc ttggctatta ctatttctgg tttgtcaggc
      241 tatatgaaaa cagaagattt acaagcgcta gatgctagta aggactttat cccttattat
      301 gagagtgatg gccaccgttt ttatcactat gtggctcaga atgctagtat cccagtagct
      361 tctcatcttt ctgatatgga agtaggcaag aaatattatt cggcagatgg cctgcatttt
      421 gatggtttta agcttgagaa tcccttcctt ttcaaagatt taacagaggc tacaaactac
      481 agtgctgaag aattggataa ggtatttagt ttgctaaaca ttaacaatag ccttttggag
      541 aacaagggcg ctacttttaa ggaagccgaa gaacattacc atatcaatgc tctttatctc
      601 cttgcccata gtgccctaga aagtaactgg ggaagaagta aaattgccaa agataagaat
      661 aatttctttg gcattacagc ctatgatacg accccttacc tttctgctaa gacatttgat
      721 gatgtggata agggaatttt aggtgcaacc aagtggatta aggaaaatta tatcgatagg
      781 ggaagaactt tccttggaaa caaggcttct ggtatgaatg tggaatatgc ttcagaccct
      841 tattggggcg aaaaaattgc tagtgtgatg atgaaaatca atgagaagct aggtggcaaa
      901 gattagtact ataagtgaat atgatttgag tgaatagtaa gttaaaaatc ctgatttcaa
      961 gtaaaatcag gattttttca tggatgcaat ttttttggag tctggtgtga cgcggagggt
     1021 cttttgtcct gtgtaagtga caaagccggg ttttccacca gttggtttat tgagtttttt
     1081 gacttcaatc atatctacct gcaccagatt cgacaggcgc ccttgagaga agtaggcagc
     1141 taactctgct gcgtctgtct tgactgcatc agatgggtca agatttcctg agatgacaac
     1201 atggcttcca ggaatgtcct tagcatggaa ccaaagttcc tccttgcggg ccattttaaa
     1261 ggtcaattcc tcattttgaa gattgtttcg tccgacatag atgatggttt tgccatcgct
     1321 tgctagatat tgttctagtt ttttgcgttt ctggattttc tcccgttgtc ttctgcggat
     1381 aaaacctgtt tgaatcaatt cttcacggat ttcagcgatt tcttccagtc cagcttggtt
     1441 gaggacggtt tctacacttt ccagatagag aatagtggct ttggtttctt caatcaaatc
     1501 agtcaagtat ttgacagctt ctttgagttt ctgataccgt ttaaaatagc gttgggcatt
     1561 ctggttggga gtcagagcct tatcaagcgc aatcatgata ggttggttgg tatagtagtt
     1621 gtctaggata acctggtctt ggtcgttagg cacttggtgg aggaaggttg tcagcaattc
     1681 tcctttttga cgaaattctt cagcgttgtc tgtcgccagt aactcttttt cctgtttttt
     1741 gagtttgtgt cggtttttct gaagttcatt ttcaacacga cgaatcagtt cactggcctg
     1801 ctgtttgacg cggtcgcgct cagccttatc cttatagtag gtgtccaaca aatcagaaag
     1861 atttgcaaga ggctctccca cctgatttgc aaaaggaact ggactgaagg aagtctcagt
     1921 caagcatggc ttggtttctt gattgaaaaa atttcggaaa gcggaaagtt tttcactaac
     1981 cagtatcctt tccaattcat ttgccgtatc gcgtcccaga ccttgaaaga ggctttgaag
     2041 attttttgct gttagttctt gggtttgcag gatttcaaag agcttttcat ccttgatagt
     2101 aaaaggattg agagattttg tacttggcgg agcgatatag gtcgatcctg gaagtaaggt
     2161 gcggtagcta ttttgtgaaa agccgacgtg tttgataact tcgaggattt tatgactgct
     2221 tttatcgacc agtagaatat tactgtgttt ccccataatt tcgataatca aggtagcctg
     2281 gatatggtct ccaatctcgt ttttattgga aactgtaatt tccacaatac ggtcattttc
     2341 cacttgctca atcgactcaa tcagggcccc ctgcaaatac tttctcaaaa ccatgataaa
     2401 ggtagaaggt tgggctggat tttcaaaagt cgtttgggtc agctgaatgc gtccaaaaac
     2461 tggatgggca gaaaggagca ggcgatggct ttggcgattg ctgcggattt gcaagaccaa
     2521 ctcttgttca aaaggctgat tgattttctg gatgcgacca ttcactaatt cgcttcgcaa
     2581 ttcctcaact atgtggtgta aaaaaaatcc gtcaaatgac atcgttctct ccttgtgatt
     2641 gtattccata gtattatatc aaaaaggtag aataaaatca tggaaatgtg gtataataaa
     2701 gccaagtaaa gagaaacgag aagcacatgt atattgaaat ggtagatgaa actggtcaag
     2761 tttcaaaaga aatgttgcaa caaacccaag aaattttgga atttgcagcc caaaaattag
     2821 gaaaagaaga caaggagatg gcagtcactt ttgtgaccaa tgagcgtagt catgaactta
     2881 atctggggta ccgtgacacc gaccgtccga cagatgtcat cagccttgag tataaaccag
     2941 aattggaaat tgcctttgac gaagaggatt tgcttgaaaa tccagaattg gcagagatga
     3001 tgtctgagtt tgatgcctat attggggaat tgttcatctc tatcgataag gctcatgagc
     3061 aggccgaaga atatggtcac agctttgagc gtgagatggg cttcttggca gtacacggct
     3121 ttttacatat taacggctat gatcactata ctccggaaga agaagcggag atgttcggtt
     3181 tacaagaaga aattttgaca gcctatggac tcacaagaca ataaacgaaa atggaaaaat
     3241 cgtgacctga tatccagttt agaatttgcc atcacaggga tttttactgc tatcaaggaa
     3301 gaacgcaata tgcgaaaaca tgcagtgacg gctctagtgg tcatccttgc aggttttggt
     3361 tttcaggtgt cacgaatcga atggctcttt ctcctattga gcattttctt ggtggtagcc
     3421 tttgaaatta tcaattctgc tatcgaaaat gtggtggatt tggccagtca ctatcacttt
     3481 tccatgctgg ctaaaaatgc caaggatatg gcggctggcg cggtattagt ggtttctctt
     3541 tttgcagcct taacaggcgc attgattttt ctcccacgaa tctgggattt attattttaa
     3601 acagtaagag gaaattatga cttttaaatc aggctttgta gccattttag gacgtcccaa
     3661 tgttgggaag tcaacctttt taaatcacgt tatggggcaa aagattgcca tcatgagtga
     3721 caaggcgcag acaacgcgca ataaaatcat gggaatttac acgactgata aggagcaaat
     3781 tgtctttatc gacacaccag ggattcacaa acctaaaaca gctctcggag atttcatggt
     3841 tgagtctgcc tacagtaccc ttcgcgaagt ggacactgtt cttttcatgg tgcctgctga
     3901 tgaagcgcgt ggtaaggggg acgatatgat tatcgagcgt ctcaaggctg ccaaggttcc
     3961 tgtgattttg gtggtgaata aaatcgataa ggtccatcca gaccagctct tgtctcagat
     4021 tgatgacttc cgtaatcaaa tggactttaa ggaaattgtt ccaatctcag cccttcaggg
     4081 aaataacgtg tctcgtctag tggatatttt gagtgaaaat ctggatgaag gtttccaata
     4141 tttcccgtct gatcaaatca cagaccatcc agaacgtttc ttagtttcag aaatggttcg
     4201 cgagaaagtc ttgcacctaa ctcgtgaaga gattccgcat tctgtagcag tagttgttga
     4261 ctctatgaaa cgagacgaag agacagacaa ggttcacatc cgtgcaacca tcatggtcga
     4321 gcgcgatagc caaaaaggga ttatcatcgg taaaggtggc gctatgctta agaaaatcgg
     4381 tagcatggcc cgtcgtgata tcgaactcat gctaggagac aaggtcttcc tagaaacctg
     4441 ggtcaaggtc aagaaaaact ggcgcgataa aaagctagat ttggctgact ttggctataa
     4501 tgaaagagaa tactaagtag aggtgggctc atgcctgctt cttgttttta cagaaggagg
     4561 acttatgcct gaattacctg aggttgaaac cgtttgtcgt tgcttagaaa aattgattat
     4621 aggaaagaag atttcgagta tagaaattcg ctaccccaag atgattaaga cggatttgga
     4681 agagtttcaa agggaattgc ctagtcagat tatcgagtca atgggacgtc gtggaaaata
     4741 tttgcttttt tatctgacag acaaggtttt gatttcccat ttgcggatgg agggcaagta
     4801 tttttactat ccagaccaag gacctgaacg caagcatgcc catgttttct ttcattttga
     4861 agatggtggc acgcttgttt atgaggatgt tcgcaagttt ggaaccatgg aactcttggt
     4921 gcctgacctt ttagacgcct actttatttc taaaaaatta ggtcctgaac caagcgaaca
     4981 agactttgat ttacaggtct ttcaatctgc ccttgccaag tccaaaaagc ctatcaaatc
     5041 ccatctccta gaccagacct tggtagctgg acttggcaat atctatgtgg atgaggttct
     5101 ctggcgagct caggttcatc cagctagatc ttcccagact ttgacagcag aagaagcgac
     5161 agctattcat gaccaaacca ttgctgtttt gagccaggct gttgaaaaag gcggttccac
     5221 cattcggacc tataccaatg cctttgggga agatggaagc atgcaggatt ttcatcaggt
     5281 ctatgataag actggtcaag gatgtgtacg ctgtggtacc atcattgaga aaattcaact
     5341 aggtggacgt ggaacccact tttgtccaaa ctgtcaaagg agggactgat gggaaaaatc
     5401 atcggaatca ctgggggaat tgcctctggt aagtcaactg tgacaaattt tctaagacag
     5461 caaggctttc aagtagtgga tgccgacgca gtcgtccacc aactacagaa acctggtggt
     5521 cgtctgtttg aggctctagt acagcacttt tggcaagaaa tcattcttga aaacggagaa
     5581 ctcaatcgcc ctctcctagc tagtctcatc ttttcaaatc ctgatgaacg agaatggtct
     5641 aagcaaattc aaggggagat tatccgtgag gaactggcta ctttgagaga acagttggct
     5701 cagacagaag agattttctt catggatatt cccctacttt ttgagcagga ctacagcgat
     5761 tggtttgctg agacttggtt ggtctatgtg gaccgagatg cccaagtaga acgcttaatg
     5821 aaaagggacc agttgtccaa agatgaagct gagtctcgtc tggcagccca gtggccttta
     5881 gaaaaaaaga aagatttggc cagccaggtt cttgataata atggcaatca gaaccagctt
     5941 cttaatcaag tgcatatcct tcttgaggga ggtaggcaag atgacagaga ttaactggaa
     6001 ggataatctg cgcattgcct ggtttggtaa ttttctgaca ggagccagta tttctttggt
     6061 tgtacctttt atgcccatct tcgtggaaaa tctaggtgta gggagtgagc aagtcgcttt
     6121 ttatgcaggc ttagcaattt ctgtctctgc tatttccgcg gcgctctttt ctcctatttg
     6181 gggtattctt gctgacaaat acggccgaaa acccatgatg attcgggcag gtcttgctat
     6241 gactatcact atgggaggct tggcctttgt cccaaatatc tattggttaa tctttcttcg
     6301 tttactaaac ggtgtatttg caggttttgt tcctaatgca acggcactga tagccagtca
     6361 ggttccaaag gagaaatcag gctctgcctt aggtactttg tctacaggcg tagttgcagg
     6421 tactctaact ggtcccttta ttggtggctt tatcgcagaa ttatttggca ttcgtacagt
     6481 tttcttactg gttggtagtt ttctattttt agctgctatt ttgactattt gctttatcaa
     6541 ggaagatttt caaccagtag ccaaggaaaa ggctattcca acaaaggaat tatttacctc
     6601 ggttaaatat ccctatcttt tgctcaatct ctttttaacc agttttgtca tccaattttc
     6661 agctcaatcg attggcccta ttttggctct ttatgtacgc gatttagggc agacagagaa
     6721 tcttcttttt gtctctggtt tgattgtgtc cagtatgggc ttttccagca tgatgagtgc
     6781 aggagtcatg ggcaagctag gtgacaaggt gggcaatcat cgtctcttgg ttgtcgccca
     6841 gttttattca gtcatcatct atctcctctg tgccaatgcc tctagccccc ttcaactagg
     6901 actctatcgt ttcctctttg gattgggaac cggtgccttg attcccgggg ttaatgccct
     6961 actcagcaaa atgactccca aagccggcat ttcgagggtc tttgccttca atcaggtatt
     7021 cttttatctg ggaggtgttg ttggtcccat ggcaggttct gcagtagcag gtcaatttgg
     7081 ctaccatgct gtcttttatg cgacgagcct ttgtgttgcc tttagttgtc tctttaacct
     7141 gattcaattt cgaacattat taaaagtaaa ggaaatctag tgcgagtaaa aattaatctc
     7201 aaatgctcct cttgtggcag tatcaattac ctaaccagta aaaattcaaa aacccatcca
     7261 gacaagattg aggttttaaa gtattgtccc aaggaaagaa aagtaaccct acatcttgaa
     7321 tctaagtaga ttttatggta aaataatagg gattttaagg agtttgatat gtataaccta
     7381 ttattaacca ttttattagt attatctgtt gtgattgtga ttgcaatttt catgcaacca
     7441 accaaaaacc aatccagcaa tgtatttgat gccagttcag gtgatttgtt tgaacgtagt
     7501 aaagttcgcg gttttgaagc tgtaatgcag cgtttgacag ggattttagt ctttttctgg
     7561 ctagccattg ccttagcatt gacggtatta tcaagtagat aagaaaataa tgggcaggac
     7621 taggtctttg cctcttttta tttttaaagg atgtttgaga aggttttaca gtaaaagaaa
     7681 attaaaaaat ctagaaagaa aatatgaaag atagaataaa agaatattta caagacaagg
     7741 gaaaggtgac tgttaatgat ttggctcagg ctttgggaaa agacagttcc aaggattttc
     7801 gtgagttgat taaaaccttg tccttaatgg aaagaaagca ccaaattcgt tttgaagaag
     7861 atggtagtct gacattagaa attaagaaaa aacatgagat taccctcaag gggatttttc
     7921 atgcccataa aaatggcttt ggctttgtta gtctggaagg cgaggaggac gacctttttg
     7981 tagggaaaaa tgatgtcaac tatgctattg atggtgatac cgtcgaggta gtgattaaga
     8041 aagtcgctga ccgcaataag ggaacagcag cagaagccaa aattattgat atcctagaac
     8101 acagtttgac aacagttgtc gggcaaatcg ttctggatca ggaaaaacct aagtatgctg
     8161 gctatattcg ttcaaaaaat cagaaaatca gtcaaccgat ttatgttaag aaaccagccc
     8221 taaaattaga aggaacagaa gttctcaaag tctttatcga taaataccca agcaagaaac
     8281 atgatttctt tgtcgcgagt gttctcgatg tagtgggaca ctcaacggat gtcggaattg
     8341 atgttcttga ggtcttggaa tcaatggaca ttgtatccga gtttccagaa gctgttgtta
     8401 aggaagcaga aagtgtgcct gatgctccgt ctcaaaagga tatggaaggt cgtctggatc
     8461 taagagatga aattaccttt accattgacg gtgcggatgc caaggacttg gacgatgcag
     8521 tgcatatcaa ggctctgaaa aatggcaatc tggagcttgg ggttcacatc gcagatgttt
     8581 cttattatgt gaccgagggg tctgcccttg acaaggaagc ccttaaccgt gcgacttctg
     8641 tttacgtgac agaccgagtg gtgccaatgc ttccagaacg actatcaaat ggcatctgct
     8701 ctctcaatcc ccaagttgac cgcctgaccc agtctgctat tatggagatt gataaacatg
     8761 gtcgtgtggt caactatacc attacacaaa cagttatcaa gaccagtttt cgtatgacct
     8821 atagcgatgt caatgatatc ctagctggcg atgaagaaaa gagaaaagaa tatcataaaa
     8881 ttgtatcaag tatcgaactc atggccaagc ttcatgaaac tttagaaaac atgcgtgtga
     8941 aacgtggagc tctcaatttt gataccaatg aagcgaagat tttagtggat aaacaaggta
     9001 agcctgttga tatcgttctt cggcagcgtg gtattgccga gcggatgatt gagtctttta
     9061 tgttgatggc taatgaaaca gttgccgaac atttcagcaa gttggatttg ccttttatct
     9121 atcgaattca cgaggagcct aaggctgaaa aggttcagaa gtttattgat tatgcttcga
     9181 gttttggctt gcgcatttat ggaactgcca gtgagattag tcaggaggca cttcaagaca
     9241 tcatgcgtgc tgttgaggga gaaccttatg cagatgtatt gtccatgatg cttcttcgct
     9301 ctatgcagca ggctcgttat tcggagcaca atcacggcca ctatggacta gctgctaact
     9361 attatactca ctttaccagt ccaattcgtc gttatccaga ccttcttgtt caccgtatga
     9421 ttcgggatta cggccgttct aaggaaatag cagagcattt tgaacaagtg attccagaga
     9481 ttgcgaccca gtcttccaac cgtgaacgtc gtgccataga agctgagcgt gaagtcgaag
     9541 ccatgaaaaa ggctgagtat atggaagaat acgtgggtga agagtatgat gcagttgtat
     9601 caagtattgt caaattcggt ctctttgtcg aattgccaaa cacagttgaa ggcttgattc
     9661 acatcactaa tctacctgaa ttttatcatt tcaatgagcg tgatttgact cttcgtggag
     9721 aaaaatcagg tatcactttc cgagtgggtc agcagatccg tatccgtgtt gaaagagcgg
     9781 ataaaatgac tggagagatt gatttttcat tcgtacctag tgagtttgat gtgattgaaa
     9841 aaggcttgaa acagtctagt catagtggca gagggcgtgg ttcaaatcgt cgttcggata
     9901 agaaggaaga caagagaaaa tcaggacgct caaatgataa gcgtaagcat tcacaaaaag
     9961 acaagaagaa aaaaggaaag aaaccttttt acaaggaagt agctaagaaa ggagccaagc
    10021 atggcaaagg gcgagggaaa ggtcgtcgca caaaataaaa aggcacgcca cgactataca
    10081 atcgtagata cgctagaggc agggatggtc ctgactggaa ctgaaatcaa gagtgtacga
    10141 gctgctcgaa ttaatctcaa ggatggcttt gctcaagtga aaaatggaga agtttggctg
    10201 agcaatgttc atatcgcgcc ttacgaagag ggcaatatct ggaaccagga accagaacgt
    10261 cgtcgtaaac tcctgctcca taaaaagcaa attcaaaaat tggaacaaga gaccaaaggg
    10321 acaggaatga ccttagttcc ccttaaggtc tatataaaag atggctacgc taagcttctt
    10381 ttaggacttg ccaaagggaa gcatgactat gacaaacggg agtctatcaa acgtcgtgag
    10441 caaaatcgag atatcgcgcg tgtgatgaaa gctgttaatc agcgataaaa agaggaattg
    10501 aaaatggaaa aattagttgc ctataaacgc atgcctttgt ggaataaaca aacaatgcct
    10561 gaagctgttc agcaaaagca caatacaaaa gttgggactt gggggaaaat tactgtcttg
    10621 aagggagctc tcaagtttat tgaattgaca gaagaagggg aagttctagc tgaacacctc
    10681 tttgaagcag gggcagacaa tccaatggcc caacctcaag cctggcaccg agtggaagct
    10741 gccacagatg atgtggaatg gtacttggaa ttttattgta aacctgagga ttattttgct
    10801 aaaaaataca ataccaatcc tgttcattca gaggtcctag aggccatgca gacagtgaaa
    10861 caagggaaag ctttggattt gggttgtggt caggggcgta attctctttt tctagcccag
    10921 caagattttg atgtgacggc tgtagatcaa aatggactag ctcttgaaat cttgcaaagc
    10981 attgtggagc aggaagattt ggacatgcct gttggccttt acgatatcaa ttcagctagc
    11041 attgaacaag aatatgattt tatcgtttca acagttgttc tcatgtttct acaagcggac
    11101 cgcattccag ctattattca aaatatgcag gagaaaacca gtgttggtgg ttacaacctt
    11161 atcgtttgtg ccatggacac ggaggattat ccttgctcgg ttaatttccc attcaccttt
    11221 aaagaaggag aactggcaga ctattacaag gattgggaat tggttaagta caatgaaaat
    11281 ccaggccatt tgcaccgtcg cgatgagaat ggcaatcgta ttcaactacg ctttgcgacc
    11341 ttactagcta agaaaatcaa gtaaacacac atgaagatta ggaattttcc tgatcttttt
    11401 tcttttttac gaatgatata gaaaaggagg gaattcatgt ttgttgcgag agatgctagg
    11461 ggagaattgg taaatgtgtt agaggataaa cttgagaagc aagcatacac ctgcccagct
    11521 tgtggaggcc agctccattt gcgtcaagga ccaagtgtac ggacgcattt tgcccataaa
    11581 tccttaaaag actgtgattt tttctttgaa aatgaaagtc cagaacacct ggccaataag
    11641 gaatccctct atcactggtt gaaaaaagag acaaaggttc aattagagta cccgctttca
    11701 gaacttaaac agattgcgga tgtatttgta aatggcaatc tagctctaga agttcagtgt
    11761 agtcccttgc ctcagaaagt ccttaaagag cgaagtgagg gatatcgtag tcagggttac
    11821 caagtactgt ggttgctggg tcaaaaactg tggctcaagg agcgtttgac tcgtctacag
    11881 caaggttttc tttatttcag tcaaaacatg ggcttttatg tttgggaatt agacaaggaa
    11941 aaacaagttt taagactcaa atacctgatt taccaggatc tccgcggtaa actccattat
    12001 caaatcaagg aattttccta tggtcaaggt agtttattgg aaatattgcg tcttccctat
    12061 aagaaacaaa aaatatctca ttttacagtt tctgaggaca aggacatctg tcgctatatc
    12121 cggcaacaac tttattatca aaatctcttt tggatgaaag aacaagcaga agcctatcaa
    12181 aagggagaaa atatcctgac ttatggactg aaagaatggt atccacaaat tcgaccaata
    12241 gtgggcaaat ttttccagat tgaacaagac ttgactagct attatcagca cttttatacc
    12301 tattaccaaa aaaatcctca aaatgattgg caaaagcttt atccaccagc cttttatcag
    12361 caatatttct tgaaaaatat ggtagaatag aaaggatgga ggaatctaat ggtattacaa
    12421 agaaatgaaa taaatgaaaa agatacatgg gatctatcaa cgatctaccc aactgaccag
    12481 gcttgggaag aagtcttaaa agatttaaca gaacaattgg agacagtagc ccagtatgaa
    12541 ggccatctct tggatagtgc ggataaccta ctagaaatca ctgaattttc tcttgaaatg
    12601 gaacgccaga tggagaagct ttacgtttat gctcatatga agaatgacca ggatacacgt
    12661 gaagctaagt atcaagagta ctatgccaag gccatgacat tctacagcca gttagaccaa
    12721 gccttttcat tctatgagcc tgaatttatg gagattagcg aaaagcagta tgctgacttt
    12781 ttagaagctc aaccaaagct gcaggtttat caacactatt ttgacaagct cttgcaaggc
    12841 aaggatcacg ttctctcaca acgtgaagaa gaattattgg ctggagctgg agaaatcttt
    12901 ggttcagcaa gtgaaacctt cgctatcttg gacaatgcgg atattgtgtt cccttatgtc
    12961 ctagacgatg atggtaaaga agttcagcta tctcatggga tttacacacg tttgatggag
    13021 tctaaaaaac gtgaggttcg ccgtggtgcc tatcaagctc tttatgcgac ttacgaacaa
    13081 ttccaacaca cctatgccaa aaccttgcaa accaatgtta aggtgcaaaa ttaccgtgct
    13141 aaagttcgta actacaagag tgctcgtcat gcagccctcg cagcgaattt tgttccagaa
    13201 agtgtttatg acaatttggt agcagcagtt cgcaagcatt tgccactctt acatcgctat
    13261 cttgagcttc gttcaaaaat cttggggatt tcagatctca agatgtacga tgtctacaca
    13321 ccgctttcat ctgttgaata cagttttacc taccaagaag ccttgaaaaa agcagaagat
    13381 gctttggcag tcttgggtga ggattacttg agccgtgtta aacgtgcctt cagcgagcgt
    13441 tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg cctactctgg tggttcttac
    13501 gataccaatg cctttatgct tctcaactgg caggacaatc tggacaatct ctttactctt
    13561 gttcatgaaa caggtcatag tatgcattca agctatactc gtgaaactca gccttatgtt
    13621 tacggagatt actctatctt tttggctgag attgcctcaa ctaccaatga aaatatcttg
    13681 acggagaaat tattggaaga agtggaagac gacgcaacac gctttgctat tctcaataac
    13741 ttcctagatg gtttccgtgg aacagttttc cgccaaactc aatttgctga gtttgaacac
    13801 gccattcacc aagcagatca aaatggggag gtcttgacaa gcgatttcct aaataaactc
    13861 tacgcagact tgaaccaaga gtattatggt ttgagtaagg aagacaatcc tgaaatccaa
    13921 tacgagtggg ctcgcattcc acacttctac tataactact atgtatatca atattcaact
    13981 ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc atggtagtca agaagaccgt
    14041 gaccgctata tcgactacct caaggcaggt aagtcggact atccacttaa tgtcatgaga
    14101 aaagctggtg ttgatatgga gaaggaagac tacctcaacg atgcctttgc agtctttgaa
    14161 cgccgtttaa atgagtttga agcccttgtt gaaaaattag gattggcata aaatggttga
    14221 atcgtatagt aagaatgcta accataacat gcgtcgtcct gtcgtcaaag aagaaattgt
    14281 agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc ttgaaagaat tggaaaactt
    14341 tgcccgcaag gaaaatattc ctattattcc ccatgaaacg gttgcttatt tccgttttct
    14401 tatggaaacc atgcagccta aaaatattct ggaaattggg acggctatcg gtttttcagc
    14461 tctcttgatg gctgaacatg cgccaaatgc taagattaca actattgatc gtaatccaga
    14521 aatgattggt tttgccaagg aaaattttgc ccagtttgac agtcgcaagc aaatcactct
    14581 cctagaggga gatgcggtgg atgtcttatc tacactgaca gagtcttatg atttcgtctt
    14641 tatggattct gccaagtcta aatacatcgt ctttctgcca gaaatcctca aacatttgga
    14701 agttggtggt gtggttgtct tggatgatat ttttcaaggt ggtgatgttg ccaaggatat
    14761 tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc cttcaaaaat tatttgatgc
    14821 aaccttagac aatccagaac tcaccgcaac attagtgcct ttaggagatg gtattctcat
    14881 gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc gaatgatttt cagaaaaatt
    14941 taagaaaaaa tagtaaaata gatagagtaa cacttatctc aaaggagtag acatgaagaa
    15001 aaaattattg gcaggtgcca tcacactatt atcagtagca actttagcag cttgttcgaa
    15061 agggtcagaa ggggcagacc ttatcagcat gaaaggggat gtcatcacag aacatcaatt
    15121 ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc ttgttaaata tgaccatcca
    15181 aaaagttttt aaaaaacaat atggctcaga gcttgatgat aaagaggttg atgatactat
    15241 tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt gtcttgtcac aagcaggtat
    15301 gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa ttagttgagt tggcagttaa
    15361 gaaggtagca gaagctgaat tgacagatga agcctataag aaagcctttg atgagtacac
    15421 tccagatgta acggctcaaa tcatccgtct taataatgaa gataaggcca aagaagttct
    15481 cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta gccaaagata attcaactga
    15541 tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat tctgcttcaa cagaagtacc
    15601 tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat ggtgtttctg atgtgattac
    15661 agcaactggc acacaagcct acagtagcca atattacatt gtaaaactca ctaagaaaac
    15721 agaaaaatca tctaatattg atgactacaa agaaaaatta aaaactgtta tcttgactca
    15781 aaaacaaaat gattcaacat ttgttcaaag cattatcgga aaagaattgc aagcagccaa
    15841 tatcaaggtt aaggaccaag ccttccaaaa tatctttacc caatatatcg gtggtggaga
    15901 ttcaagctca agcagtagta catcaaacga atagtccaaa tcaatgagtc agggaaaaaa
    15961 actcgacttc aggaaaaaat gaagcaaaca ttcccacaat aaaacgcata gtacaaggtt
    16021 tgtactgacc ccaaaagtta gacaattaat ttatctgaag gatttagttc tgtattgcac
    16081 agggctaagt ccttttagtt ttaccttaat tctcttattg ttgtaataat caatatagtc
    16141 tataatggct tgttccaatt gattaagtga tttaaatgtt ttctcatagc cataaaacat
    16201 ttcggatttt aaaatgccaa agaaagattc catcctaccg ttgtcttggc tgtttccttt
    16261 gcgtgacata gatgcttgaa ttcccttact ctctaggaag cgatgataag aatcgtgttg
    16321 gtattgccag ccttggtcac tatggagaat cgtattctcg tagtgcttct ctttgaatgc
    16381 ctgttccaac attaacgatc aatcaattta atcatgtacc taatattaga attgtttatc
    16441 ccaaatttat ttgaaagctt ctctaagcta tatccttgtt ttctaagttc atagatctga
    16501 actttatcat cataagttaa tttcataata aaaacacccc aaaagttaga ttttttctgt
    16561 ctaacttttg gggtgtagtt catgtacacc tgatatgatg cgttttataa ttttaaagac
    16621 tttttgacca gcctcatttt tttaacttga tactcagtga aaagcaaaga ttaaactagg
    16681 aagctagctg taggctgctc aaagaacagc tttgaggttg cagataaaac ttgtgaggtc
    16741 accaacatat ataatgtgaa gctgacgtgg cttgaataga ttttagaagg gtatgagtct
    16801 ggaagtttta atggataatg caagattcca tagaatgggt aagctagagt tcttatgtga
    16861 agagtttggg cataaacttt taccttttcc tccctactca tcttagtata gaaaagtgaa
    16921 tctaaaatag tacataactg cttctaaaac attcttataa attgatttaa attctcaaat
    16981 catattattc agttcttatt tcattttgct ctacaatcct gttgagaaga cacgtgttca
    17041 tatcaaaaag gtattggcaa gttgcaatac ctttttacaa ggttcttttg tcttattttt
    17101 gtttcaactg actatatctc ctatggttct agttcagaag gctaggctat aattatgatt
    17161 gataagaagt atcattccaa gtattgagag tgaatgtttc aaaatcatgg gtttctataa
    17221 tggtcaggct ggcatttgct agaccgccat ctttacgaag aagtggttct ttatagccta
    17281 ggagagtacg aagactggca gtaagattgg cgccgtgtcc gacaattaga atacgctcag
    17341 ctggactatc ttttaatgat ttgataaatt ggatggtccg ttgagttgta ctatagaggg
    17401 attcggctcc gaacattcga gtgtcaaatt gagcaagatt tgaacgaaaa gcctggattt
    17461 gttgcgggta aatagcttcc aaggttgcaa ttttcaaacc ttctaacttc ccaagttgcc
    17521 attcacggag attaggaacg atttctaaag aacagggggt atagagttga ctttggataa
    17581 tctcagcaga tttgaccgct cgaggtaaat cacttgaata aatctgatca aaaggaattt
    17641 ccttgagata ctggccaagt cgttttaggg tttcaatgga ttcaggaaga agaggagaat
    17701 caccgctagc accttgaaaa cgaccttctt ggttccagag ggtacgaccg tggcggacaa
    17761 agtagagttt cattacttga tgtcctccaa aatatctaca aagtctgcct ttacaaagct
    17821 agccaagtct tgtggcgcga cgataatgct gtgtccgact tcgtctgcag agacaatcat
    17881 tcgatccaaa tctagagcaa ttttatcgat aaaaatggga taattgtgtt tctgacgaat
    17941 tccgacagga ttattggctc catgaatgta accagttgtt ttttctaagt ccttttgtgg
    18001 aatcatgctc acttttttat tgccagaaat tttagctagt ttcttttcag acaagtgctg
    18061 agtgataggg acaattccga taatcggtcc ggtcttgtct cccaaaagcg ccaaggtttt
    18121 gaaaatctga tctcgttcat aaccttgagg aagctctcct tctagggcat tgatttgaat
    18181 cccctgatga gggatagctg ctttagatag gatttgttcc accaatgttt ttttgatttt
    18241 aacttttttt gccattattt atatttatcc tccaattgac tcatccaaat accaagccag
    18301 attcccagcg caaagaagaa ggcgatgatg acataaccga caagtgaaag tcctgtgtat
    18361 tggatacttt cagcgtttcc tgcatttgga attaagatca aaagggtact tgataggacg
    18421 ataccgatga tgaaatgata gacgcgtgag tggtagttgt ttaaggcata atccatcaat
    18481 tttgaaaaaa cgatgagagt tgcacctgca ccaattccaa tcggaaagaa ggttcccaag
    18541 agatcaaaag ttttaaaacc agtcaacata ggagcataga gtcccaaaat caaaagtaag
    18601 ttcgatgggc tgaggccagg aaccaagacg ccaagggcca atagtgcgcc tgctaggacg
    18661 aagttaagaa agctggcgct taaggttcca acgacaaaat ttaaggcata gagtcctaat
    18721 ccagaaatga taaaggttgt ccataaccaa gctaaatcaa tcttgtctcg gtcagattct
    18781 cgagttgatt ctttgaggag gctaggaact gtaccgataa tagctcccgc aaagctccat
    18841 aatacaaaga cctgataatt ttcaagcagg tattcaatcg ggtaggaaaa taagccgatt
    18901 cccagaagca taccgatggc aactggaata aagtacaaaa cattttcttt aaggtcttta
    18961 aagggatggg ccagaaagcc aatcattcgt tcatagattc ctaagattgc tgctagaacc
    19021 cctccggaaa ttcccggtag gataaatcca agagcaatta caatcccttt aataacgcgt
    19081 gctaaccatg agagcatata tttcctccaa ctatttctat ttcaaaaaat ccttactata
    19141 ttgtatcaca atcagacaca aaaagaaaaa gcaaatgata aacaaatgct tttaaggttt
    19201 taaaaaaagt tttcgaaagg tttcttcttt attttttaag ggagagataa cgttgatatc
    19261 taaatcgtgg tcaaagccgg caatttttcc tttagatgtg tattggtgaa tatcataatc
    19321 taaatcagtt ttaggactgc tctccaaaaa tcctgagtct gagccgtagg acggaatcca
    19381 aacagaggta aacttgcctg tatcaatact gtgttcttcc atgaagtaga caccaacgta
    19441 gatgccgatg tttttagcac ctagtgatgc tagttttgct cgaaagtttt cgacaccttc
    19501 gttcatatta gacatggttt tgtcttccac gtcaagccaa tagtaactag ggctgtaagg
    19561 agaggcagca ttgtagaaaa cttcggcagc cttttccatt tcttggacac tttttccagc
    19621 tacataagcg tagacagcaa ctgggacatt ccgcttttga agttcagtga tatgactctt
    19681 ataggccttg tctattccat tgataaatga agcatcattt tcttttgttg tttgagcacc
    19741 actgtgaaca cgaacaatag cacctgaaat attttgtgag agggcatcgt agttgatttc
    19801 ctcaggacgc tgccagccag agaggtcaat aatcggtttg tctaagtgtt tcaaagcctg
    19861 tgcttcaatc tgtgctatat tggattttgt tttaaacgat tggctgtcat taagtgggcg
    19921 attgatgatt aaaatgaaca tcataatccc aaaaaaacta aataaaataa gtggatgaat
    19981 ttgttttctc atatcttata agtctaccct aaaaatcaaa aaaaatcaaa aaaatgggtt
    20041 aaggaagaga ctttagagca ttttttcatt caagagtgcg gaatgatttg aaatatggta
    20101 taataaaagg gaatttctac agaaaagaga agattatgtc aaattttgcc attattttag
    20161 cagcgggtaa agggactcgc atgaaatctg atttgccaaa agttttgcac aaggttgcgg
    20221 gtatttctat gttggaacat gttttccgta gtgtgggagc tatccaacct gaaaagacag
    20281 taacagttgt aggacacaag gcagaattgg ttgaggaggt cttggctgga cagacagaat
    20341 ttgtgactca atctgaacag ttgggaactg gtcatgcagt tatgatgaca gaacctatct
    20401 tagaaggttt gtcaggacac accttggtca ttgcaggaga tactccttta atcactggtg
    20461 aaagcttgaa aaacttgatt gatttccata tcaatcataa aaatgtggcc actatcttga
    20521 ctgctgaaac ggataatcct tttggctatg gacgaattgt tcgtaatgac aatgctgagg
    20581 ttcttcgtat tgttgagcag aaggatgcta cagattttga aaagcaaatc aaggaaatca
    20641 acactggaac atacgtcttt gacaacgagc gtttgtttga ggctttgaaa aatatcaata
    20701 ccaataacgc tcaaggcgaa tactatatta cagacgtcat tggtattttc cgtgaaactg
    20761 gtgaaaaagt tggcgcttat actttgaaag attttgatga aagtcttggg gtaaatgacc
    20821 gtgtggcgct tgcgacagct gagtcagtta tgcgtcgtcg catcaatcat aaacacatgg
    20881 tcaacggtgt tagctttgtc aatccagaag caacttatat cgatattgat gttgagattg
    20941 ctccggaagt tcaaatcgaa gccaatgtta ccttgaaagg gcaaacgaaa attggtgctg
    21001 agactgtttt gacaaacggt acttatgtag tggacagcac tatcggagca ggagcggtca
    21061 ttaccaattc tatgattgag gaaagtagtg ttgcagacgg tgtgacagtc ggtccttatg
    21121 ctcacattcg tccaaattca agtctgggtg cccaagttca tattggtaac tttgttgagg
    21181 tgaaaggatc ttcaatcggt gagaatacca aggctggtca tttgacttat atcggaaact
    21241 gtgaagtggg aagcaacgtt aatttcggtg ctggaactat tacagtcaac tatgacggca
    21301 aaaacaaata caagacagtc attggagaca atgtctttgt tggttcaaat tcaaccatta
    21361 ttgcaccagt agaacttggt gacaattccc tcgttggtgc tggttcaact attactaaag
    21421 acgtgccagc agatgctatt gctattggtc gcggtcgtca gatcaataaa gacgaatatg
    21481 caacacgtct tcctcatcat cctaagaacc agtaggagcc tatcatggag tttgaagaaa
    21541 aaacgcttag ccgaaaagaa atctatcaag gaccaatatt taaactggtc caagatcagg
    21601 ttgaattacc agaaggcaag ggaactgccc gacgggattt gattttccac aatggggctg
    21661 tctgtgtttt agcagtaacg gatgaacaaa aacttatctt ggtcaagcag taccgcaaag
    21721 ctatcgaggc tgtctcttac gaaattccag ccggaaaatt ggaagtagga gaaaacacag
    21781 cccctgtggc agctgccctt cgtgaattag aggaagaaac agcctataca gggaaattag
    21841 aactcttgta cgatttttat tcagctattg gcttttgtaa tgagaagtta aaactatatt
    21901 tagcaagcga tttgacaaaa gtggaaaatc cgcgtccgca ggatgaggat gaaaccttgg
    21961 aagtccttga agtgagctta gaagaagcga aagaattaat ccaatcaggt catatctgtg
    22021 atgccaagac aattatggct gttcagtatt gggagttgca gaaaaaatag aggaggtcag
    22081 tatgggtaaa tctttattaa cggatgaaat gattgaaaga gctaatagag gcgaaaaaat
    22141 ttcaggtcct cctttgctag atgataatga ggaaactaag attttaccaa cctcttcttc
    22201 ccgttttggt tatgccaatc ctaaggatca tggttttagc caggaaacct tgaagattca
    22261 ggtcgaacca tctattcata aaagccgtcg tattgaaaat accaagagaa atgtcttcaa
    22321 ttctaagttg aataaaatct tatttgcggc catctttctc ttgattttgc ttgttttagc
    22381 aatgaaactt ttgtaataga aaaggaattg aaatgaaaat aggaattatt gctgctatgc
    22441 cagaagaact ggcttatctg gtccagcatt tagataatac ccaggagcaa gttgttttgg
    22501 ggaataccta tcatacagga accattgctt ctcatgaagt cgttcttgta gaaagtggaa
    22561 ttggtaaggt catgtctgct atgagtgtgg cgattttggc tgatcatttc caggtggatg
    22621 cccttattaa tacgggttca gctggggcag tagcagaagg tatcgctgtt ggggatgtcg
    22681 tgattgctga caaattagcc tatcatgacg tggatgtcac agcttttggc tatgcttatg
    22741 gacaaatggc gcaacaaccg ctttatttcg aatcagacaa aacctttgtt gctcaaatcc
    22801 aagagagttt atctcaattg gaccaaaact ggcatcttgg tttgattgct acaggagata
    22861 gttttgttgc aggaaatgac aagatagaag cgattaagtc ccatttccca gaagttttag
    22921 ccgtggagat ggagggggca gctattgctc aagcagcgca tgccctcaat ctcccagtct
    22981 tagtcatcag agctatgagt gacaatgcca accatgaagc aaacatcttt tttgatgagt
    23041 ttattatcga agctggacgt cgctctgccc aagtcttgtt gacctttttg aaggctttag
    23101 attaagcgga aatttgacag tttttctagc ttatgataag atttaagtaa agaaaagcta
    23161 gaaaacgttt cagaggatat tatgagtatt gaaatgaccg tcagtgagat tgcagaggtc
    23221 ttaggattat ctcgccaagc aatcaataac cgtgtcaaag aattaccaga agaagacaca
    23281 gataaaaatg acaaaggggt aacagttgtt accagaagtg gcttgattaa gctagaagaa
    23341 atctataaaa aaacgatttt tgaagatgag cctgtcagtg aagatgtcaa acaacgtgaa
    23401 ctgatggaga ttctagtgga tgagaagaat gcagaaattc ttcgtcttta tgaacaatta
    23461 aaagccaagg atcgtcagtt atcagaaaaa gacgagcaga tgcgtatcaa agaccgtcag
    23521 attgctgaga aagacaaaca attagatcag caacaacaat tgacccttca agccatgaag
    23581 gatcaagaaa atcttaagct agagctggac caagcaaaag aagaagtcca atccactaag
    23641 aaaggctttt ttgctcgttt atttggagga taatcaagga gctgtttagg ttaaatgcta
    23701 acctgatggc ttcttttgtt tgtgaatagt atagttgatt agaacagaga cagtagagga
    23761 gaggtacaga atggaacgat tagaagatta cattgctttt gacttagaat ttaatcagca
    23821 cgaaggacaa acacacttga ttcaagtatc ggcagtgcgt tttagagatg gtcgggaaat
    23881 cgatgcctat gattcctatg ttcataccag cgtccctcta aaaagcttta tcaatggttt
    23941 gaccgggatt acagctgaga ccttaaaaga tgctcctcca gttgagaaag tcttagaaga
    24001 attccaagag tttgtgggtt ctttgctgat gataggctac aatgctgcta aaagtgattt
    24061 acctatttta gcagatcatg gtttagacta tagccaacag tacaaggtgg atttgtatga
    24121 tgaagctttt gaacgtcgga gttcagattt acatggtatt gccaatctca aattgcaaac
    24181 tgttgcctca tttcttggat ttcaaggtca gtctcataat agtttagagg atgctcggat
    24241 gacggcgcgt gtttacgaat ccttcttaga gtcggatcaa gctagggaat tgttagagac
    24301 agaaagtagc ttatcaaaca atccttttgg tgtcttggac ttgtctcaat tatttgacta
    24361 ggagtgccta tgaaacctga aaaacctaaa aaattgggtc ttaaacagat ttacctcaat
    24421 cttgataaaa tcctctttct atttttcttg atttttatga tagtggagta tttgtgggta
    24481 ccattcaatt catggttggc tagcttctta ttagatcaga caggttatct ttttatttcc
    24541 tataacaatg tcttagccat ccttactcat tctccattga ttagtctagc ttttttagcc
    24601 ttgattgtaa ttaaccttct ggttgcttat tttcaaatag gactcctctt tattggtgct
    24661 cgtcatctcc tctataatga aaagcgaagg ctaattgagt atatccgcaa ggttttccat
    24721 gaaagttttg gatttatgaa aaagctaact tgcgctaaag ccttgtttat ctttttctat
    24781 atagctatgc tttttccttt tatacggaaa atgctgaaga tttattatct taataaaatc
    24841 gtcattccag agtttatcca agcttattta gaagataaat attggatgtg gtggctgagc
    24901 atcctacttc tatctcttat ctttctctat gtctctgtca gattgatgtt tgcccttccg
    24961 aagattgtat atgatcagct gactgttcga gaagcagtga tgtttagctt ggagaaaacc
    25021 aagaagagag ttacttttta tgcttggaat ttattttaca tcttgctcaa agcacattta
    25081 ttattttatc ttcctttgat tcctttatta ttggctcaaa ctttggtaga tgatatcact
    25141 cagagagagt ctctgattct tggtattttg aattttgtcg tgattaaaaa tctctattat
    25201 atggctctga cttatttttt ggttaaattt gtttcatttt tgacaggaaa ggagctggat
    25261 atgcttccta ggagagaaaa agatcacatc gtgcgatggg gtgtcatgac ttgtgccagt
    25321 cttttctttg ccttagaagg ttatatttat ctggaggctc ccatggttca tctacctcaa
    25381 cttatttctc accgaggggt ttccaatgca aatgggattc aaaatacagt agagtccttg
    25441 gaaactacag cacaactcaa accagacttg gtggagacgg acgtgcagga aacaaaagat
    25501 gggcagtttg tcatgatgca tgatgctaac ttgaaaaatc tagcaggtat caataaaagt
    25561 cctcaagact taaacttgga ggagcttaaa gggattgata tttttgaaaa tggctaccag
    25621 actaaaattt caagctttga agattatctc agtcgagcca acgaacttgg tcaaaaatta
    25681 ctaattgaaa ttaaaaccag taaaaaagat agtccagaca tgatgaaccg ctttttagcc
    25741 cgttatgctg caaagctcaa gatttatgga catcaaatcc agtctttaga ctaccatgtt
    25801 gtcgaaaaag taagacagta tgatgccgaa ctgccagttt atttcatcat gccctacaat
    25861 tctgtctttc ctaaaacaag agcgacagga tatactatgg agtactcaac cttggatgaa
    25921 tattttgtaa gcaaactatg gacaacggat cagaaacttt atgtctggac tgtcaatgat
    25981 tcagaagcta tcagcaaatc tcttcactta ggagtagatg gagtgattac agatgatttg
    26041 gaaaaagttc agcgggaaat agaagtagcc caagaagatc cagaatatac ggatttgctc
    26101 ttgaaaaaag cattggaatt ctttgaattt tagtaataaa aaagaggaac ggttgttcct
    26161 cccatgatag gtaagtattc ttgtgaatgc ttgctttttt gtggttgcaa tccgtttacg
    26221 agaattgttt gtattgttct tgtttcaatt tactttatag tgctttgaag ttggaatgct
    26281 acactataac ttctaaa
//
LOCUS       DAYYYC010000027        25154 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.027, whole genome shotgun sequence.
ACCESSION   DAYYYC010000027 DAYYYC010000000
VERSION     DAYYYC010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25154
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.027"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            78..149
                     /locus_tag="ACHBV5_001229"
     tRNA            78..149
                     /locus_tag="ACHBV5_001229"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Glu,seq:ttc)
     gene            155..228
                     /locus_tag="ACHBV5_001230"
     tRNA            155..228
                     /locus_tag="ACHBV5_001230"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:189..191,aa:Asn,seq:gtt)
     gene            complement(269..811)
                     /locus_tag="ACHBV5_001231"
     CDS             complement(269..811)
                     /locus_tag="ACHBV5_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFM9967026.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(1071..2324)
                     /locus_tag="ACHBV5_001232"
     CDS             complement(1071..2324)
                     /locus_tag="ACHBV5_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFM9967027.1"
                     /translation="MKCFVGLDISSTKLDVCIMLSDTSTPVTASLSNDLSGATEIKNH
                     ILDLNHTYHFERIVIGMEATSLYSFHPAMFFHEDRQLKELHVEIMVEQPNKIKKYRDA
                     FEENKNDTIDAFYIADYFRIERFSPSFLKEEKYMALQHLTRTRLQIIEQLTRTKQHFI
                     ENIYYKCNTLAYQFKKEELSTNLWSSTMMTLMTDEMTLDELANMPLQELDDWLQKLGK
                     GHFKDSEKLAQTIQAAIRGSYRLSKLQQDSVNVILGLLAREIRNLEKMIKEIDKAIED
                     MVETIPEYQCLTSIPGVGKVYAAGIIAEIGQIERFKDHPQVAKFAGLNWREKQSGNSN
                     SQHTSLVNRGNRYLRYYLVEAANSVRRYDDEYKDFYKKKYHEVPKHQHKRAILLTARK
                     FVRLVDVLLRNHQLYTPPRRIMEDN"
     gene            2680..4438
                     /locus_tag="ACHBV5_001233"
                     /pseudo
     CDS             2680..4438
                     /locus_tag="ACHBV5_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(4468..7011)
                     /locus_tag="ACHBV5_001234"
     CDS             complement(4468..7011)
                     /locus_tag="ACHBV5_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFM9967028.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLSPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYTLMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVLFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSTYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVDFDY
                     FSPIPYEKIENTNNLISVTSSSNEDAAIQYQIEVPENSQIYLSFINLHFSNDKQKKVD
                     ILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFT
                     EAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQT
                     GFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(7073..8695)
                     /locus_tag="ACHBV5_001235"
     CDS             complement(7073..8695)
                     /locus_tag="ACHBV5_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFM9967029.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            8901..9926
                     /gene="trpS"
                     /locus_tag="ACHBV5_001236"
     CDS             8901..9926
                     /gene="trpS"
                     /locus_tag="ACHBV5_001236"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFM9967030.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            10078..11556
                     /gene="guaB"
                     /locus_tag="ACHBV5_001237"
     CDS             10078..11556
                     /gene="guaB"
                     /locus_tag="ACHBV5_001237"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFM9967031.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(11607..12704)
                     /gene="recF"
                     /locus_tag="ACHBV5_001238"
     CDS             complement(11607..12704)
                     /gene="recF"
                     /locus_tag="ACHBV5_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFM9967032.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKTSVNGN"
     gene            complement(12707..13075)
                     /gene="yaaA"
                     /locus_tag="ACHBV5_001239"
     CDS             complement(12707..13075)
                     /gene="yaaA"
                     /locus_tag="ACHBV5_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFM9967033.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            13234..14484
                     /locus_tag="ACHBV5_001240"
     CDS             13234..14484
                     /locus_tag="ACHBV5_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFM9967034.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            14481..15764
                     /locus_tag="ACHBV5_001241"
     CDS             14481..15764
                     /locus_tag="ACHBV5_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFM9967035.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTIDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            15806..16627
                     /gene="rodZ"
                     /locus_tag="ACHBV5_001242"
     CDS             15806..16627
                     /gene="rodZ"
                     /locus_tag="ACHBV5_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HFM9967036.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            16638..17183
                     /gene="pgsA"
                     /locus_tag="ACHBV5_001243"
     CDS             16638..17183
                     /gene="pgsA"
                     /locus_tag="ACHBV5_001243"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFM9967037.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            17180..18007
                     /locus_tag="ACHBV5_001244"
     CDS             17180..18007
                     /locus_tag="ACHBV5_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFM9967038.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            17992..18831
                     /locus_tag="ACHBV5_001245"
     CDS             17992..18831
                     /locus_tag="ACHBV5_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HFM9967039.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            18824..19618
                     /locus_tag="ACHBV5_001246"
     CDS             18824..19618
                     /locus_tag="ACHBV5_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFM9967040.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            19677..20495
                     /gene="mreC"
                     /locus_tag="ACHBV5_001247"
     CDS             19677..20495
                     /gene="mreC"
                     /locus_tag="ACHBV5_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFM9967041.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            20495..20989
                     /gene="mreD"
                     /locus_tag="ACHBV5_001248"
     CDS             20495..20989
                     /gene="mreD"
                     /locus_tag="ACHBV5_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFM9967042.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            21083..22261
                     /gene="pcsB"
                     /locus_tag="ACHBV5_001249"
     CDS             21083..22261
                     /gene="pcsB"
                     /locus_tag="ACHBV5_001249"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HFM9967043.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            22485..23264
                     /gene="rpsB"
                     /locus_tag="ACHBV5_001250"
     CDS             22485..23264
                     /gene="rpsB"
                     /locus_tag="ACHBV5_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003036542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFM9967044.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNK"
     gene            23330..24370
                     /gene="tsf"
                     /locus_tag="ACHBV5_001251"
     CDS             23330..24370
                     /gene="tsf"
                     /locus_tag="ACHBV5_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFM9967045.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            24616..24939
                     /gene="tnpB"
                     /locus_tag="ACHBV5_001252"
     CDS             24616..24939
                     /gene="tnpB"
                     /locus_tag="ACHBV5_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFM9967046.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSDQV
                     FLFCGGRKDRFKVLYWDGQGFWILYKRFENGKLTWSSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
BASE COUNT         7948 a         4095 c         5154 g         7957 t
ORIGIN      
        1 ttttagagaa aaaatctcaa aagtgattga caattagcaa gaaattgata taatggttat
       61 atctgctaca gatagaaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg
      121 taacacgggt tcgaatcccg tacggactat tttatccgcc atagctcagt tggtagtagc
      181 gcatgactgt taatcatgat gtcgtaggtt cgagtcctac tggcggagta tagataaaag
      241 ggaacacagc tgtgttcctc tttttgtatc aatttgtatc accaagcatt ttcataagga
      301 agtctgttat ttcttgagaa ctttcttttt ttccatgtgc aatccaagtt tggcagacac
      361 caaaaagtgc atgagttaga tagatgctac tatattctaa ttcagtggta tttagattca
      421 gttgcataaa tcgcttttgt aaatctgtac taagcatgat atgaagttta tttcgtaaga
      481 aattttggat ttctttagtc ccattttcag aaagaagggc agccagaagt ggttctgact
      541 ctagatattc aaaaacttct aaaatagcgt ctcttttgtg atgagcatgt ttttgaaaaa
      601 tatattcaaa tgtatggaat agcttgcttt gatagtgctc aatcatatca tacttatcct
      661 tatagtgagt atagaagctg gaacgactaa ttccggcttt ttctactaat ttgacagtag
      721 aaattttatc aaatggctgt tccatcagta attgtaccat agcgttttca atagttcgct
      781 ttgtttttaa gcgtttgtta ctttcttgca tatttcctcc ttgtaaacaa attagactat
      841 atgtctaaaa atagattttt tatcttgtaa tttagatttt ttaatgtata atctattata
      901 tcaaaatttt agacaatatg tttaaaaaag tctagtggta aaatgtcaag cgaccccccg
      961 ctcaaagttt gaaaactatt tcaaaaaaag ggtgcactaa agaagcccta ctgaaaacga
     1021 tgttttcaca ctgtttttag tagattttca aggagaggtg cagatataac ttagttatct
     1081 tccataatcc tccttggtgg cgtatagagt tgatggttgc gtagtagcac atccaccaga
     1141 cgcacaaatt ttctagcggt tagtaagatg gctcgtttgt gttggtgttt aggtacttca
     1201 tggtatttct tcttatagaa atccttgtat tcgtcatcat aacgccttac cgagttggcg
     1261 gcttcaacca ggtagtagcg cagataacga ttgcccctat tcacaagcga agtatgttgt
     1321 gagtttgagt taccagattg cttttctctc caattcagac cagcaaattt tgcgacctgg
     1381 ggatggtctt taaagcgttc gatttgtcca atttcggcaa tgataccagc agcgtagacc
     1441 ttcccgaccc caggtatgga ggtcaggcat tgatattcag gaatggtttc caccatatct
     1501 tcaatggcct tatcaatttc cttgatcatt ttttccaggt ttcgaatttc ccgagccaga
     1561 agtccgagaa tgacattgac tgaatcttgt tggagtttag agaggcgata agaacctctg
     1621 atagcggctt gaatggtttg agcaagcttc tcagagtcct taaaatgccc tttacccagt
     1681 ttttggagcc aatcatctaa ttcttgaaga ggcatgttag caagttcgtc taaggtcatc
     1741 tcatctgtca tcaaggtcat catcgttgaa ctccataggt tagtagagag ttcttctttc
     1801 ttgaattgat aagccaaggt attgcacttg tagtagatat tttcaatgaa gtgctgtttg
     1861 gttctggtta attgctcgat gatttggagt ctggttcttg tgagatgttg gagagccatg
     1921 tatttctctt cttttaaaaa agaaggtgaa aatcgctcaa tacggaaata atccgcaatg
     1981 tagaaagcat caatggtatc gtttttgttt tcttcgaaag catcccgata cttcttgatt
     2041 ttattaggtt gttcgaccat aatctcaaca tgtagttctt tcaactgcct atcttcatgg
     2101 aagaacatag cagggtggaa actgtagaga ctggttgctt ccatgccaat gacaatcctt
     2161 tcgaagtgat aggtatgatt caaatcaagg atatgattct taatctctgt tgccccagaa
     2221 aggtcattag agagggaagc agtgacgggg gtgctagtat cactcaacat gatacacaca
     2281 tctaattttg tagagctgat gtctaaaccg acaaaacatt tcattaagga aggtctcctt
     2341 tccattagat ttggaagttt ttttgactac tgtaaggttt cccagaaaca ccttgttcca
     2401 acatcctcgc ataagagaat ccttatcaca gcctgacaga gccgcctgca tcctactaga
     2461 tacagaagtc aagctgtgga aacagctagt gtgttggaag tttgaacaag gcttgggtaa
     2521 cagacttttt aatgaagtcc aagcaacaag gagaaaaaga aacaaccatg agtccattcc
     2581 atgactctat tgttctagaa aaccttgcaa tagtcaagtg ataacgaata aaacttggga
     2641 ttgaaatatc cccatgatta tatattacga ggagaaacta tgtttaaaga atggaaagca
     2701 atttaaaaaa aacaaccttt attattgtca tgatcgggat ttctcttatt ccagctctgt
     2761 acaatatcat atttttgtca tcaatgtggg atccatatgg gcaattgtct gacttacctg
     2821 tggcagttgt aaataatgat aaagaggctt cctataatgg taatactatg gcaataggaa
     2881 aagacatggt gtccaattta aaagaaaata aaaccttgga ttttcatttt gtagatgaag
     2941 aggaaggaaa gaagggattg gaagatggcg attactatat ggtagtgact ttaccaagtg
     3001 atttatctga aaaagcaact acattatcca atattcaatc gacagcagct tatcaatcat
     3061 tgacaagtga gcaacaaact gagataagtg attctgtatc tcaaaattca actgatagta
     3121 ttcaatcggc tcagtcaatt gtagctttag tacaagattt acagggaagt ttagaaaact
     3181 tacaaaatca atcttctaat ctttcgactt taaaaaatca agctaatcaa gtattaccta
     3241 ttacttctac ttctttgata ggattgtcaa gtggattaac agagatacaa ggagctgtta
     3301 ctagcaaatt agttcctgcc agtcagtcga ttgcatcagg tgtaaacgca tatactacag
     3361 gtgttgataa agtttctcag ggcgcaagtc aactaagtga aaaaaatgct accttgacag
     3421 gtagtttgga tcaattagtt tcaggctcaa acaccttgac acaaaaatct tctagcttga
     3481 cagcaggagt tggtcaatta gttgaaaaaa ctccagaatt agtatctggt attgaaaaat
     3541 tatcaactgg ctccaattaa ttgaatcaaa agagtcaaga attgatagca ggagttgata
     3601 aattgcagtc aggctctagc caactagctg acaaatccag tcagttactt tcaggtgttt
     3661 ctcaattaga aagtggagct aataaattgg cagatggagc tgggaaacta gcagaaggtg
     3721 gaacaaagtt aacttctgga ttggaaggtt tacagacagg acttgcttct ttaggacaag
     3781 gactaggtaa tgctagtgat caactcaaat cagcatcaac agaatctaaa aatgcagaga
     3841 ttttgtcaaa tccactcaat ctttccaaaa cagacaatga ccaagttcct gtaaatggaa
     3901 ttgcaatggc tccttatatg atatcagttg ctctttttgt tgcagcaata tcaacgaata
     3961 tgatctttgc gaagttacct tcaggacgtc atccagagag ccgttgggct tggttgaaat
     4021 ctcgagctga aataaatggt attatagctg ttttggcagg gattttggta tatggaggag
     4081 ttcatcttat tggtctaact gctaatcatg aaatgagaac atttattctc atcatcttaa
     4141 caagtttagt attcatgtct atggtgaccg ctttaacaac atggaatagc cgtataggag
     4201 ctttcttctc gcttattttt cttttattac agttagcatc aagtgcaggt acctatccgc
     4261 ttgctttgac aaatgatttc tttagagcta ttaatccttg gttgccaatg agttattcag
     4321 tttcgggatt acgacaaaca atctccatca acaagtcatt ttcctagctg tcatactagc
     4381 tctatttact ggtttaggta tgctagccta tcaacctaag aaaatggaag aagattaaaa
     4441 aaatcgaccg attaactggt cgatttttta tgccttagat gactttcgtc tgtgattata
     4501 gattccaaat agtaagagag aagtaaagga acagattgct ccagtaataa aaccattggg
     4561 aatgaaggaa agtgtaatag ttcctttccc cttgggaatg tcaactttca taaatccagt
     4621 ttgagcttgt ttaatttcta ttttcttacc atcttggtag gcagaccaac ctttgtcata
     4681 aggaatggtg aagaaaatag atgtatcttg ttggacatca tatgtagcaa aaaccttgtt
     4741 tttagaagtt gatactgtga caggttgttc tttaattttt tgaattgcct cggtgaaagt
     4801 tttggtatct aaacgataga aggtaggaga ttcaaatgat acttgtgaat ttccagggaa
     4861 actaacattg atattgaaag tttttttctc tttagtatat cctagattaa agaaggagaa
     4921 gacattatca gttgtaaaag tctttttttc accatttaca aggatgtcaa ccttcttttg
     4981 tttatcgtta gaaaagtgaa ggtttatgaa agagagataa atttggctgt tttctggaac
     5041 ttcaatttga tactggattg ctgcatcctc atttgaagaa cttgtgacac taatcaaatt
     5101 attagtattt tctatttttt cataagggat tggagaaaaa taatcaaaat caacgttagc
     5161 aagttgattt aaaaacgagg cctgattatc caaggtatgt tcattgaact tgacatcatt
     5221 gtaaacagat tgactagcaa ctgcaatcgg aagagagtat tgattttcat atagggtaag
     5281 attatctttt tgatagatat ctttaaaacc atacttatca ataggactgt ctgagatatt
     5341 gtactggata ccaaataaac tatcagccaa aatactatta tttgcatatc ggagattgag
     5401 attagtccca gaggatttaa acccaagttt atctaaagta gagcttgatg aacgatttcg
     5461 aacagatgaa aattgagaga ttccattgta gttgaatttc atactgtcat ttcctgtctg
     5521 agtttgtagt ttttcagtac gagtaaattg atttccaata tatgttgaga aagattccat
     5581 agctgggata tctcgactat aagtacttcg agaagcaaat ccccattcct tagcaattcc
     5641 gtccatttga gatgaagcat ttaaactcat ttcaaccagt ataaataaag agattagaat
     5701 ggcaaataga ttcacagata taaacttttt gataactgca aggagtaaaa gagaatagac
     5761 aaccaaaaat tcaagagtaa gcagaatatt caaatctgtt aaaaaagaat aatgcgattt
     5821 tagatagatg gtagctaaaa atcctgttac tacaagaaaa agcgaaacta aaaaattcca
     5881 gactttaagt tctttcagac gctttaagac ttctgctgct gtgtaaatta acaaggtaga
     5941 gaaaatccaa gcatagcgat gtaaaaacat gtttggagta tgcatgcctt gccaaaataa
     6001 gtcaagagct tctatgtaaa agcttgcaat tagaaatgca aagaataata catatatgag
     6061 tttcacgtga aacttaatag atttcagcgt aaaaaataaa atggtcaaaa taaaaggaag
     6121 tagtccaaca aaaatcattg ggatggcccc atactttgtt gtgtcaaagg aaccaatgaa
     6181 ttgcttagca aagagatcaa gataccagct actttcagtt tgaaactttg taacttcagt
     6241 caatttttcc ccatgtgtct gtaaatcaaa cagagtggga agagtcataa tcaaactagc
     6301 cataccagct aaaaaggaga taactatgaa atcaagaaca gatgattttc gagtcttaaa
     6361 gtcccacgaa atttgacaga gataccagaa aataagaaac aatactgtca tatatccaaa
     6421 ataataattt tgaataaata agattgacag acttgtaaag tacaatagga gtttcttttc
     6481 agttatcagt agatgtaaac cagttataat taaaggaatc aagataaaaa catctagcca
     6541 ggtttttatc tctaattgac tgacagtgaa actcatcaga gtataggaag tagataaggc
     6601 tagttttaaa gtctgaggga tagattgaaa caatttattc aaactaaaaa aggttgacag
     6661 accaatcaat ccaaatttta agagagtggt cagataaaca gcatctggca tattcgttag
     6721 atcaaaaaag taaaccagag gtgagagaaa actacccaag taataactag acagagcata
     6781 gaagtttagc cctagaccac ttgtaaaggt gtaaaacaga ctactatttc catgtaggat
     6841 atttcgtaag gctacatcaa aaataacgta ttgatgaaag ccatctccta atagaggaga
     6901 gttgtcgcta ttccagtaga taccttgaga tagatatact ccagacataa tcactacagg
     6961 aatgatgaga gaaataaaat aggttcgata tgtttttaaa aatgatttca tgttacctcg
     7021 tagaatgata gaaaactcag ttggttaacc caactgagtt ttgaagtttt atttagtctt
     7081 tccaaagttc tttaactttt gcttgtactt ctgcattttc taggaattca tcgtaggttt
     7141 catcgatacg gtcaatgacg ccatttttag ataagacaat gatatggtta gccaaagttt
     7201 gaataaattc gtggtcatgg ctagcaaaga tgattgattc tttaaagttt ttcaatccat
     7261 cattcaagct tgagatagat tccaagtcca agtgatttgt tggatcatca agtacaagga
     7321 catttgattt taagagcatg agttttgaaa gcatgacacg aactttttct ccccctgaca
     7381 agacatttac aggtttgtta acttcatctc cagagaagag catacggccg aggaagccac
     7441 gtaggaaagt attgtcatct tcttctttac ttgcgaattg acgcaaccag tcaagaattg
     7501 attctcctcc tgcaaaatca gctgagttat cttttggtag gtaagattga ctagttgtaa
     7561 ctccccactt gacagttcct tcatagtcaa tatctcccat gattgcacga attaatgcag
     7621 tcgtttgaat atcattttgt ccaataagtg ctgtcttatc atctggacgc aagatgaaac
     7681 taatattatc caagatagtt tcaccatcaa tctttacagt tagattttct actgtcaaga
     7741 gatcattacc aatctcacgt tccgctttaa agttgataaa tggatattta cgactagatg
     7801 gtacaatctc ttctagctca atcttatcaa gcattttctt acgtgatgtt gcctgccttg
     7861 acttagaagc attggcagag aaacgagcaa cgaattcttg caattgttta attttttctt
     7921 ctgctttagc attacggtct gctagcaatt tagcagcaag ctcagaagat tccttccaga
     7981 agtcgtagtt tccgacatag agtttgattt ttccaaagtc aaggtcggcc atgtgagtac
     8041 aaactttgtt taagaagtga cggtcgtggg atactacgat aactgtgtta tcaaagtcaa
     8101 tcaagaagtc ttctaaccaa gtaatcgatt ggatatccaa accgttagta ggctcgtcca
     8161 agagaagaac atctggttta ccaaaaagtg ctttggcgag gagaaccttt actttttcac
     8221 cgttggccaa ttcgctcatg ttttggtagt gtaattcttc tggaatgttt aggttttgaa
     8281 gtagttgaga ggcttcactc tctgcttccc aacctccaag ttcggcaaac tctccttcga
     8341 gttcggcagc acgaaccccg tcctcgtctg agaaatcttc cttcatgtag atagcatctt
     8401 tctctttcat gatgctataa agtttttcat ttcccatgat aacgacatca atggcacgtt
     8461 catcttcgta gtcaaagtga ttttgacgaa gaacagagag acgttcatct ggaccaagag
     8521 agatgtgacc agtagtaggt tcgatatctc cagctaaaat ttttaaaaag gttgattttc
     8581 cggcaccatt agcaccgatt aatccgtaag tatttccttc tgtaaatttg atattgacat
     8641 catcaaaaag tttgcgatca ctaaaacgta gtgaaacatc agatactgta agcaatattt
     8701 ttctcctata tgtgtaatat atttattcta ctagaaaata cagaaatatt caaattttta
     8761 tttgtcaatt ttgtgtaaat tatatttaca gtatccttta cacaaatctg taaaaagcaa
     8821 ggctgattta ttttgataaa ttacggttat ttcattaaaa aaatgctata attgaaagga
     8881 ctatatcgaa ggagaacaaa atgactaaac ccattatttt aacaggagac cgtccaacag
     8941 gaaaattgca tattggacat tatgttggaa gtctcaaaaa tcgagtatta ttacaggaag
     9001 aggataagta tgatatgttt gtgttcttgg ctgaccaaca agccttgaca gatcatgcca
     9061 aagatcctca aaccattgta gagtctatcg gaaatgtggc tttggattat cttgcagttg
     9121 gattggatcc aaataagtca actattttta ttcaaagcca gattccagag ttggctgagt
     9181 tgtctatgta ttatatgaat ctagtttcgt tagcacgttt ggagcgaaat ccaacagtca
     9241 agacagagat ttctcagaaa ggatttggag aaagcattcc gacaggattc ttggtctatc
     9301 caatcgctca agcagctgat atcacagctt tcaaggctaa ttatgttcct gttgggacag
     9361 atcagaaacc aatgattgag caaactcgtg aaattgttcg ttcttttaac aatgcatata
     9421 actgtgatgt cttggtagag ccggaaggta tttatccaga aaatgagaga gcagggcgtt
     9481 tgcctggttt agatggaaat gctaaaatgt ctaaatcact aaataatggt atttatttag
     9541 ctgatgatgc ggatactttg cgtaaaaaag taatgagtat gtatacagat ccagatcata
     9601 tccgcgttga ggatccaggt aagattgagg gaaatatggt tttccattat ctagatgttt
     9661 ttggtcgtcc agaagatgct caagaaattg ctgatatgaa agaacgttat caacgaggtg
     9721 gtcttggtga tgtgaagacc aagcgttatc tacttgaaat attagaacgt gaactgggtc
     9781 ctattcgtga gcgccgtatt gaatttgcta aggatatggg agaagtttat aatatgattc
     9841 aaaaaggtag tgaaagagcg cgtgaagttg cgggtcaaac cctatctgag gtaaaagggg
     9901 caatgggact tcattacttt aactaagttt attttacaag aaactatcat ttctatctcg
     9961 aagaaaagat agttttttat ttacccctgt aacatttgac aaatttttat agaatggtat
    10021 gatagataca atataaaaag agtcaagctc aaaaagaaag aaaagaggaa acttcgaatg
    10081 tctaattggg acactaaatt tttgaaaaaa ggttttacct ttgatgatgt attgcttatt
    10141 ccagctgaaa gtcatgtgtt gcctaacgat gcagatttaa caactaaatt ggcagataat
    10201 ttgactttaa atatcccaat tattaccgct gccatggaca cagttacaga gagtcaaatg
    10261 gccattgcta ttgctcgtgc aggtggtctc ggagttatcc ataaaaacat gtcaattgct
    10321 caacaagcag acgaggttcg taaggtaaaa cgttctgaaa atggagttat tattgatccg
    10381 ttcttcttga cgcctgaaca tacaattgct gaagcagatg agcttatggg tcgttaccgc
    10441 atcagtggtg ttccagttgt tgaaacactt gaaaatcgta aattggttgg tattttgaca
    10501 aaccgagatc ttcgttttat ttcagattat aatcaaccaa tttcaaacca tatgactagt
    10561 gaaaatcttg ttactgctcc tgtgggtacg gatcttgcaa cggctgagag tattcttcaa
    10621 gagcatcgta ttgaaaaact tccgttggtc gatgaagaag gcagtctttc tggtttgatc
    10681 actatcaaag atattgaaaa agttattgag tttccaaatg cggctaaaga tgaatttggt
    10741 cgtcttctag ttgcaggtgc agtaggtgtt acttcagata catttgaacg tgcagaggct
    10801 ctttttgagg caggagcgga tgcgattgtt attgatactg cacatggtca ttctgcaggt
    10861 gtcttgcgta aaattgccga gattcgtgct catttcccag atcggacttt gattgctgga
    10921 aatattgcta ctgctgaagg tgcacgtgcc ctttatgaag cgggtgtaga cgttgttaag
    10981 gttggtattg gaccaggttc tatctgtact actcgtgtga ttgctggtgt tggtgttccg
    11041 caagtaacag ctatctacga tgctgcagct gttgcgcgcg aatatggtaa aacgattatt
    11101 gctgacggtg ggatcaagta ttctggagat attgtaaaag cacttgctgc aggtggaaat
    11161 gctgttatgc ttggatctat gtttgctgga actgatgaag ctccaggcga aactgaaatc
    11221 ttccaaggac gtaaattcaa gacttaccgt ggtatgggat caattgctgc tatgaagaaa
    11281 ggttcaagcg accgttattt ccaaggttct gtcaatgaag caaacaagct cgttccagaa
    11341 ggaattgaag gtcgtgttgc ttataaagga gcggcagctg atattgtttt ccaaatgatt
    11401 ggtggtattc gctctggtat gggttactgt ggtgcagcta accttaaaga actacacgat
    11461 aatgctcaat ttattgaaat gtctggtgct ggtttgaaag aaagccatcc tcatgatgtg
    11521 caaattacta atgaggcacc aaattattct atgtaaaaaa caatgaaaag aactccagtg
    11581 aaaacaggag ttcttttaca atgttgtcaa tttccattta cagaagtttt accatcctga
    11641 atagtgaaga tacttagatt ttctggcaga ttttgaagat ggtctaagct tgttgttgtg
    11701 ataaaggttt ggattgattg agaaatcgtt tctaataatt ttaactgtct agtgttgtca
    11761 agttcactca tcacatcgtc aagcagtaat ataggagatt ctgtggtaat gctttccatt
    11821 aattcgattt ctgctaattt tatcgagagg acgagactac gatgttgacc ttggcttccg
    11881 aaactagcat ccatcccatt tatataaaaa gaaatgtcat ctcgatgagg accgacacca
    11941 gtattctttt taaataaatc tctggatcta cttttttcta aagcaatttt gaaagattcg
    12001 gataagtttt gtttgtcagt tatattgaca gaagattgat aggatattga caactcttcg
    12061 atctgattag agagttcaaa atgtttctta cgcccaaatg attctagttt ttttatgaaa
    12121 tctaagcggt gattcattac acgacatcca taatcaacta gctgatcatc taacacagaa
    12181 aggaatgttt catctatttt ttgagctgat tttaggtaag tgtttctttg ctttaggatg
    12241 tggttataat tggttaagtc agataaatag attggcttaa tttgcccaag ttccatatca
    12301 atgaattttc gtcgaatcga aggtgctcct ttaattagtt gtaaatcttc aggagcaaat
    12361 aagacaacat tcatgtgtcc tacataatct gaaaggcgtg cctgttttaa gtgattaact
    12421 tttgttacac ggcctttttg tgttagttcg atttctaggg gaatggatcc agtttttttc
    12481 tgaacgagac ctgaaagatg aagttgttcc tcatcaaaat gaatgagatt tttatctgtt
    12541 cgagttcgat gactacgcgt taaggctaaa aaatagatag cctctaacat gtttgttttt
    12601 ccttgtgcat tacgtcccaa aaagacattc aatttaggat taaagtctat tttcgtttct
    12661 ttgtaattac gaaaagtctt gagagataga tgttgtagcc acatgattat ctaccaggga
    12721 atcgtggagc ttgttggctt ttaggtgatg aagcaggttt cgatttgtct tttttaactc
    12781 ccttattcat ctttttgaca agtttagcga tccgttcttt ttcaacttta tcagcttggt
    12841 attcatcttg ttcttcagaa gtaggttgtg tcaacaagat gtcaatgttc atgtcaggga
    12901 tgtcaacttt atcgccaata cgaagttttt ttccacgacg actctctaat tccctattaa
    12961 agtaaacaga atgttcagag agaaatgatt taatagctcc tccgctatgt gtaattccaa
    13021 gttctttgag tagtgcttgg agggtaataa attcttcaaa taatttgtat tccataattc
    13081 acctcaatct ttggtattat accatatttt cctaaaaata gtgagagaga cagcgagaaa
    13141 tgtaagcgat ttttatttca aaagtgttac agggaacaag aaaatttcag gttttcgtga
    13201 tataatagaa gtctgtatat aaggaggtaa atcatggagt tagtgcatgg aatttcaaca
    13261 cattttatcc aatcaaaaaa gtttaaaaca aacaaaatta ccgtgcgttt taccgctcca
    13321 ttatcccttg atacgattgc aggtcacatg ttgagtgcaa gtatgctaga gactgctaat
    13381 cagatgtacc ccacttctca agatttgagg agacacttgg ccagtctata cggtacagat
    13441 atgtcaacca attgtttcag aagagggcaa agccacatta tagaattgac atttacctat
    13501 gttcgtgatg agtttttaag taggaaaaac gtgctaacct ctcagatttt ggaacttgta
    13561 aaagaaactc ttttttcacc cgcagtagtt gataatgggt ttgatccggc cttatttgaa
    13621 attgagaaaa aacaattgct agcaagttta gcagctgata tggatgattc tttttatttt
    13681 gcacataaag aattggataa attgtttttt catgatgaac gtcttcaatt ggaatatagt
    13741 gatttacgaa atcgtatttt agctgaaact ccacaaagtt cttattcttg tttccaagaa
    13801 tttttagcca atgatcgaat agatttcttt ttcctaggtg attttaatga ggttgaaatt
    13861 caaaatgtat tagaatcatt tggctttaaa ggtcgaaaag gagatgtgaa ggttcagtat
    13921 tgtcaacctt attctaatat ccttcaggaa ggtatggttc ggaaaaatgt gggacaatcc
    13981 attttggaat taggttatca ttaccgttct aaatatggtg atgagcaaca tttacccatg
    14041 attgtaatga atggtttact tggtggattt gctcactcta agctctttac aaatgtccgt
    14101 gaaaatgctg gattagctta taccatttca agtgagcttg atttatttag tggattcttg
    14161 aggatgtatg ctggtatcaa tcgagaaaat cgtaaccagg ctcgtaaaat gatgaataat
    14221 caactgcttg atttaaaaaa aggttatttt acagagtttg agttaaatca gaccaaggaa
    14281 atgattcgtt ggtcgttgtt actttctcaa gataatcaat cttcattgat tgaacgtgct
    14341 tatcaaaatg ccttatttgg aaaatcttca gcagacttta aaagttggat tgcaaagctt
    14401 gaacaaattg acaaagatgc tatttgtaga gtagctaata atgtgaaact acaagcgatt
    14461 tactttatgg aaggaataga atgacaaagg ttgtttttga agaaaaatac tatccagctg
    14521 taaaagaaaa ggtttatcga actcgtttgg ccaacggatt gacagttgct cttttgccta
    14581 aaaaggaatt taaagaggtt tacgggagtg tcactgtaca gtttggttcg gtagatacgt
    14641 ttgtcacaga agttgacgga tatgtaaaac aatatcctgg aggaattgct cattttcttg
    14701 aacataaatt atttgagaga gaagattcta gtgatttgat gtcggctttt acgagtctag
    14761 gtgcagatag taatgccttt acaagcttta caaaaacaaa ctatcttttt tcagcaacgg
    14821 attatttttt agaaaattta gatttacttg atgaattggt aacatcagca cactttactg
    14881 aagcttccat tctgacagag caggatatta ttcagcaaga acgagaaatg taccaagatg
    14941 atccagattc gtgtttattc ttttcaactt tagcgaattt gtatcctggt acacctttag
    15001 caactgatat agttggaagt gaggagtcca tttcccaaat caatctaact aatttgcaag
    15061 aaaattttac aaagttttac aaacctgtaa acatgtctct gtttttagtt ggtaattttg
    15121 atgtggagcg agtacaggac tattttgaaa gcaaagaact gaaagattca gattttcagg
    15181 aagtagcaag agaaaagttg tttttacagc ctgtaaagcc aacagatagt atgagaatgg
    15241 aagtatcttc tcccaaacta gcgattggag ttagaggtaa gcgagaagtt tctgaagcgg
    15301 attgctatcg acatcatatt ttattaaaat tattgtttgc aatgatgttt ggttggactt
    15361 cggatcgttt tcaaaaatgt tatgaatcag gtaaaattga tgcgtcctta tctctggaag
    15421 ttgaaataac aagtcgcttt cattttgtca tgttgacaat agatacgaaa gagccagttg
    15481 ctttgtctca tcaatttagg aaggctattc gtaattttac aaaggattta gatattacag
    15541 aggaacattt agatattatc aaaagagaga tgtttggcga atttttcagt agcatgaact
    15601 ctcttgaatt tattgcaacg caatatgatg cttttgaaaa tggtgagaca atttttgatt
    15661 tgccgaaaat tttacaggaa attactttag aggatgtcct tgatgctgga catcatttaa
    15721 tagatgatgg tgacatagtt gattttacaa tattcccatc gtagtaacct atcataatag
    15781 acactagaaa gaagggatga caagtatgag aaaaaaaaca attggagagg ttttacgatt
    15841 agctagaatc aatcagggat tgagtttaga tgaattgcag aaaaagacag aaatccagtt
    15901 agatatgttg gaagcaatgg aagcagacga tttcgatcaa cttccaagtc ctttttacac
    15961 gcgttctttc ttgaaaaaat atgcatgggc tgttgagtta gatgaccaaa ttgttttgga
    16021 tgcttatgat tctgggagta tgattactta tgaggaagta gatgttgatg aagatgagtt
    16081 gacaggtcgt agacgttcaa gtaagaaaaa gaagaaaaaa acatcatttt tacctttatt
    16141 ttattttatc ctttttgctt tatcgatttt aatttttgtg acttattatg tttggaacta
    16201 tattcaaact caaccagagg agccttctct ttctaattac agtgtggttc aatcaacaag
    16261 ttcaactagc tctgttcccc actcctcaag tagtagttct tctagtatag aatcagctat
    16321 aagtgtatca ggcgaaggaa atcatgtaga aatcgcttat aagacaagta aggaaacagt
    16381 taaattgcaa ttggcagttt cagatgttac aagttgggtc agtgtttcag aaagcgaact
    16441 tgagggcggt gtaaccttat cgccaaagaa gaaaagtgca gaagcaacag ttgcaactaa
    16501 aagtcctgta acaattacgt taggtgttgt aaaaggtgtt gatttgacag tagataatca
    16561 gactgttgat ttatcgaaat taacagctca gactggacaa atcactgtaa cctttactaa
    16621 aaattaagga aaaacgaatg aaaaaagaac aaattcccaa tctcttaaca ataggtcgaa
    16681 ttctctttat acctattttt atctttattt tgacgatagg aaattcgata gagagtcata
    16741 tagttgcagc tattatcttt gctgttgcca gtattaccga ctatttagat ggatatttag
    16801 ctcgtaaatg gaatgtggtc agtaattttg gtaaatttgc agatcctatg gcggataagt
    16861 tactagttat gtcggctttt attatgttga ttgagttagg tatggctccg gcttggattg
    16921 ttgcagtgat tatctgtcgt gagttagctg tgacaggttt aaggctttta ttggttgaaa
    16981 ctggtggaac aattttagca gcagcaatgc ctggaaaaat taaaactttt agtcagatgt
    17041 ttgctattat tttcttgcta ttacattgga ctttgcttgg tcaagttcta ctttatgtag
    17101 ccttattttt cactatctac tctggctatg actatttcaa gggtagtgcc tatgtattta
    17161 aagggacatt tggttcgaaa tgaaatcaat aattgatgta aaaaatcttt cttttcgcta
    17221 taaagaaaat cagaactact acgatgtgaa ggatattacg tttcacgtga aacgtggaga
    17281 atggctttcg attgtagggc ataatggtag tggtaaatca acgacggttc gattaattga
    17341 tggcttactg gaagcagaat ccggagagat tgtaattgat ggccaacgtt tgactgagga
    17401 aaatgtttgg aatatacgtc gtcaaatcgg tatggttttt caaaatccag acaatcaatt
    17461 tgttggagcg actgttgaag atgatgttgc ttttggtttg gaaaatcagg gactttctcg
    17521 tcaagaaatg aaaaagagag tggaagaagc tctggcttta gttggcatgt tggactttaa
    17581 aaagagagag ccagcgcgtc tatcaggtgg ccaaaagcaa cgtgtggcca ttgcaggtgt
    17641 tgtagcccta agaccagcta ttttaatctt agatgaagca acgagtatgt tggatcctga
    17701 ggggcgtaga gaacttattg ggacagtaaa aggaattcga aaagactatg atatgacggt
    17761 catttctatt acccatgatt tggaagaagt cgccatgagt gatcgcgtat tggtcatgaa
    17821 aaaaggggaa attgaatcaa ctagtagtcc aagggagctt ttctctcgaa atgatttaga
    17881 tcaaattgga ttagacgatc cttttgctaa tcaattaaaa aaatctttga gccagaatgg
    17941 ctatgattta cctgaaaatt atttgacaga aagtgagcta gaggataagc tatgggaatt
    18001 gctctagaaa atgtgaattt tatatatcaa gaaggtactc ccttagcttc agcagctttg
    18061 tcggatgttt ctttgacgat tgaagatggc tcttatacag ctttaattgg gcacacaggt
    18121 agtggtaaat caactatttt acaactctta aatggtttat tggtgccaag tcaagggagt
    18181 gtgagggttt ttgatacctt aatcacctcg acttctaaaa ataaagatat tcgtcaaatt
    18241 agaaaacagg ttggcttggt atttcagttt gctgaaaatc agatttttga agaaacggtt
    18301 ttgaaggacg ttgcttttgg accgcaaaat tttggagttt ctgaagaaga tgctgtgaag
    18361 actgcgcgtg agaaactggc tctggttgga attgatgaat cactttttga tcgtagtccg
    18421 tttgagctgt cagggggaca aatgagacgt gttgccattg caggcatact tgccatggag
    18481 ccatctatat tagtcttaga tgagccaaca gctggtctag atcctctagg gagaaaagag
    18541 ttgatgaccc tgttcaaaaa actccaccag tcagggatga ccatcgtctt ggtaacgcat
    18601 ttgatggatg atgttgctga atatgctaat caagtctatg taatggaaaa gggacgttta
    18661 gtaaaggggg gcaaaccaag tgatgtcttt caagacgttg tttttatgga agaagttcag
    18721 ttgggagtac ctaaaattac ggccttttgt aaacgattgg ctgatagagg cgtgtcattt
    18781 aaacgattac cgattaagat agaggagttc aaggagtcgc taaatggata gtatgatttt
    18841 ggggcgttat atcccagggg attcgattgt tcaccgattg gatccacgta gcaaattgct
    18901 tgctatgatg ctactgattt tgattgtgtt ttgggctaat aaccccttga cgaatctgat
    18961 tctttttata gcgacaggga tatttattgc cttgtcagga gtatctcttt cattttttat
    19021 tcagggcttg aagtctatgt ttttcttgat tgccttcaca actatttttc aactattttt
    19081 catttctaat gggaatgttt tatttgagtt ttcgtttgtg agaatcacgg attatgcttt
    19141 gcaacaagct gggattattt tttgtcgctt tgtattgatt attttctttt caactttgtt
    19201 aaccttaaca accatgcctt taagtttggc atcagctgtc gaagctttat tagcaccttt
    19261 aaagcgtgtg aaagttccag ttcatgaaat tggattgatg ctgtctatga gtttgcgttt
    19321 tgtcccaacc ttgatggatg atacgactcg gattatgaat gcacagaaag ctcgtggagt
    19381 ggattttgga gaaggaagca tcgttcaaaa agtaaaggcg atgattccca ttttgattcc
    19441 tctttttgcg acaagtttaa aacgtgcaga ttccttggct atcgctatgg aagcgcgtgg
    19501 ctatcagggt ggaaaaggca gaagtcaata ccgacaattg aaatggactc taaaggatac
    19561 gctgaccatt cttgttattc tcgtacttgg ttgttgttta tttttcttaa aatcttagta
    19621 gctttcagga attgataaaa agttactgta acagtttttg atataaaggt agggatatga
    19681 accgttttaa aaaatcaaaa tatgtcatta ttgtttttgt cactgttctg cttgtgtcag
    19741 ctctcttagc gacgacttat tcaagtacaa ttgtgacaaa attaggagat ggaatctcat
    19801 tggttgatag agttgtacaa aaaccttttc agtggtttga ttctgtcaaa tcagatttgg
    19861 ctcatttgac acgaacatat aatgaaaatg aaagtttgaa gaaacagctt taccaattag
    19921 aagttaaatc aaatgaggtg gaaagtttaa agacagaaaa tgaacaactg cgccaattgc
    19981 ttgatatgaa gtctaaattg caagccacaa agactttagc agcagatgtt attatgcgtt
    20041 ctccggtatc ttggaagcag gagttgacct tagatgcagg tagatcaaaa ggtgcttctg
    20101 agaacatgtt agctattgca aatggtggct tgattgggag tgtttcaaaa gtagaggaga
    20161 actctactat agtcaacctt ctgacaaata cggaaaatgc tgataagatt tctgttaaaa
    20221 ttcaacatgg ctctactaca atttatggaa ttattattgg ctatgacaag gaaaatgacg
    20281 ttcttaaaat tagccaatta aatagtaata gcgatattag tgcgggagat aaggtgacta
    20341 ctggtggatt aggaaacttt aacgttgctg atattcctgt tggtgaagtg gttgccacaa
    20401 cgcatagtac agactatttg acacgagaag taactgttaa attgagtgca gatactcata
    20461 atgtagatgt gatagaatta gtggggaatt cataatgaga cagttgaagc gagttggagt
    20521 atttttattg cttcctttct ttgttctaat tgacgcccat attagccagc ttctgggctc
    20581 atttttcccc catgtacatt tggctagtca ttttcttttt ctatttctct tatttgagac
    20641 gatagaagta tcagagtatc tctacctagt ctattgtttt gttataggct tggtttatga
    20701 tgtttacttt ttccatctaa tagggattac aactctctta tttatcttat tgggagcctt
    20761 ccttcataaa ttgaatagtg ttattttgtt gaatcgttgg acaagaatgc tagctatgat
    20821 tgtgctgaca ttcctgtttg aaatgggtag ttatcttttg gcttttatgg tagggttgac
    20881 agtagatagc atgtcgattt ttatagtcta tagcttggta ccgacgatga ttttaaattt
    20941 tttatggatt actgtttttc aatttatttt tgaaaaatat tatctataag aacgacatat
    21001 aaatgtaaca aaggcgtaat atttattagg cctttttttg gtatactagt attgtcttta
    21061 aaagaaggag tatctacgta atatgaagaa aaaaatctta gcgtcacttt tattaagtac
    21121 agtaatggtt tctcaagtag ctgttttaac aactgcgcat gcagaaacga ctgatgacaa
    21181 aattgctgct caagataata aaattagtaa cttaacagca caacaacaag aagcccaaaa
    21241 acaagttgac caaattcagg agcaagtatc agctattcaa gctgagcagt ctaacttgca
    21301 agctgaaaat gatagattac aagcagaatc taagaaactc gagggtgaga ttacagaact
    21361 ttctaaaaac attgtttctc gtaaccaatc gttggaaaaa caagctcgta gtgctcaaac
    21421 aaatggagcc gtaactagct atatcaatac cattgtaaac tcaaaatcaa ttacagaagc
    21481 tatttcacgt gttgctgcaa tgagtgaaat cgtatctgca aacaacaaaa tgttagaaca
    21541 acaaaaggca gataaaaaag ctatttctga aaaacaagta gcaaataatg atgctatcaa
    21601 tactgtaatt gctaatcaac aaaaattggc tgatgatgct caagcattga ctacgaaaca
    21661 ggcagaacta aaagctgctg aattaagtct tgctgctgag aaagcgacag ctgaagggga
    21721 aaaagcaagt ctattagagc aaaaagcagc agctgaggca gaggctcgtg cagctgcggt
    21781 agcagaagca gcttataaag aaaaacgagc tagccaacaa caatcagtac ttgcttcagc
    21841 aaacactaac ttaacagctc aagtgcaagc agtatctgaa tctgcagcag cacctgtccg
    21901 tgcaaaagtt cgtccaacat acagtacaaa cgcttcaagt tatccaattg gagaatgtac
    21961 atggggagta aaaacattgg caccttgggc tggagactac tggggtaatg gagcacagtg
    22021 ggctacaagt gcagcagcag caggtttccg tacaggttca acacctcaag ttggagcaat
    22081 tgcatgttgg aatgatggtg gatatggtca cgtagcggtt gttacagctg ttgaatcaac
    22141 aacacgtatc caagtatcag aatcaaatta tgcaggtaat cgtacaattg gaaatcaccg
    22201 tggatggttc aatccaacaa caacttctga aggttttgtt acatatattt atgcagatta
    22261 atttacagag ggactcgaat agagccctct tttcaggttt taccgtgaca atccctatta
    22321 aaaattatat caaaatagct tgaaaatatt ggaaaagtat ggtaaaatga aaattgtcgt
    22381 gtgaacgata atactcattc ttgatgaatt gtgaagcagt tgcccttggg tcgttttgcg
    22441 agttgaagtc aagaagagga aaaaaacaaa aaggagaaat actcatggca gtaatttcaa
    22501 tgaaacaact tcttgaggct ggtgtacact ttggtcacca aactcgtcgc tggaatccta
    22561 agatggctaa gtacatcttt actgaacgta acggaatcca cgttatcgac ttgcaacaaa
    22621 ctgtaaaata cgctgaccaa gcatacgact tcatgcgtga tgcagcagct aacgatgcag
    22681 ttgtattgtt cgttggtact aagaaacaag cagctgatgc agttgctgaa gaagcagtac
    22741 gttcaggtca atacttcatc aaccaccgtt ggttgggtgg aactcttaca aactggggaa
    22801 caatccaaaa acgtatcgct cgtttgaaag aaattaaacg tatggaagaa gatggaactt
    22861 tcgaagttct tcctaagaaa gaagttgcac ttcttaacaa acaacgtgcg cgtcttgaaa
    22921 aattcttggg tggtatcgaa gatatgcctc gtatcccaga tgtgatgtac gtagttgacc
    22981 cacataaaga gcaaatcgct gttaaagaag ctaaaaaatt gggaatccca gttgtagcga
    23041 tggttgacac caatactgat ccagatgata tcgatgtaat catcccagct aacgatgacg
    23101 ctatccgtgc tgttaaattg atcacagcta aattggctga cgctattatc gaaggacgtc
    23161 aaggtgagga tgcagtagca gttgaagcag aatttgcagc ttcagaaact caagcagatt
    23221 caattgaaga aatcgttgaa gttgtagaag gtgacaacaa atagtaatta cctaggaggg
    23281 cggggcttag cccggctctc ctattttcaa aaaatatagg agaattaaaa tggcagaaat
    23341 tacagctaaa cttgtaaaag agttgcgtga aaaatctggt gccggtgtta tggacgctaa
    23401 aaaagcgctt gtagaaacag acggtgacat cgaaaaagcg attgaattgc ttcgtgaaaa
    23461 aggtatggct aaggcagcta agaaagctga ccgtgttgct gcagaaggtt tgactggtgt
    23521 ttatgttaac ggtaatgttg cagcagttat tgaagtaaac gctgaaactg acttcgttgc
    23581 aaaaaacgct caattcgttg aattggtaaa tactacagct aaagtcattg ctgaaggaaa
    23641 acctgctaat aatgaagaag ctcttgcttt gataatgcct tcaggtgaaa ctcttgaagc
    23701 tgcatacgta tctgcaacag caactatcgg agagaaaatc tcattccgtc gctttgcatt
    23761 gattgaaaaa acagacgcac aacactttgg agcataccaa cataacggtg gacgtatcgg
    23821 tgttatttca gttgttgaag gtggagacga agcacttgct aaacaattgt caatgcacat
    23881 cgcagcgatg aaaccaacag ttctttctta caaagaattg gatgagcaat tcgttaaaga
    23941 tgagttggca caattgaatc acgttatcga ccaagacaac gaaagccgtg caatggttaa
    24001 taaaccagct cttccacact tgaagtatgg atcaaaagct caattaactg atgatgttat
    24061 tgctcaagct gaagctgaca tcaaagctga attggctgca gaaggcaaac cagaaaaaat
    24121 ctgggacaaa attatcccag gtaaaatgga tcgcttcatg cttgataata ctaaagttga
    24181 ccaagcttac acacttcttg cacaagttta catcatggat gacagcaaga cagttgaagc
    24241 ataccttgaa tcagttaacg cttcggtagt tgagtttgct cgctttgaag ttggtgaagg
    24301 tatcgagaaa gctgcaaacg acttcgaagc tgaagttgca gctacaatgg cagcagcctt
    24361 gaataactaa taatagaaag gaagcaaatt gcttcctttt ttgtataggg cttagatttt
    24421 tcctgaaatt gttttttccc cagtctcact cgattagaat aattaaaaca aaaagcccta
    24481 taataagggc taagtgcatt taggagacta tacttcaaat tcatagtaag cgcgtcataa
    24541 caaggtatct atcctaattc cccaacttcc agtataccag ataaaaaata attatcggag
    24601 gaaaggtatt gtactatgat aattcaacta agtgatttag gtcaagttca ccttgtttgt
    24661 ggcaagacag atatgaggca gggaatagac tcattagcct atgtagttaa aacccacttt
    24721 gaattggatc ctttctccga tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
    24781 aaagttcttt actgggatgg tcaaggattt tggatattat ataaacgctt tgagaacgga
    24841 aaactgactt ggtccagtac agaaaaggat gtcaaagctc tcacatctga acaagtagat
    24901 tggctgatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
    24961 cacctctgct tctaaaacat tgttagaaat cgatttgact atcctgttct tatttcattt
    25021 tactataaat tcatcagaaa gtcgtgattt ctattgaaat gaggactttc tttttatact
    25081 catctgtttt caaaaagcat tctagtccgt ctccgattaa cgatggactt tatcacctcc
    25141 ttctccagtc cttg
//
LOCUS       DAYYYC010000028        24323 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.028, whole genome shotgun sequence.
ACCESSION   DAYYYC010000028 DAYYYC010000000
VERSION     DAYYYC010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24323
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.028"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(68..1843)
                     /gene="spxB"
                     /locus_tag="ACHBV5_001253"
     CDS             complement(68..1843)
                     /gene="spxB"
                     /locus_tag="ACHBV5_001253"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HFM9967047.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2050..4293)
                     /locus_tag="ACHBV5_001254"
     CDS             complement(2050..4293)
                     /locus_tag="ACHBV5_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFM9967048.1"
                     /translation="MTEIVKASLENGIQKIRIRSEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4303..4674)
                     /locus_tag="ACHBV5_001255"
     CDS             complement(4303..4674)
                     /locus_tag="ACHBV5_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HFM9967049.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(4685..5080)
                     /locus_tag="ACHBV5_001256"
     CDS             complement(4685..5080)
                     /locus_tag="ACHBV5_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFM9967050.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5264..5362
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5446..6237
                     /gene="thiD"
                     /locus_tag="ACHBV5_001257"
     CDS             5446..6237
                     /gene="thiD"
                     /locus_tag="ACHBV5_001257"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFM9967051.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQAKDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(6446..7078)
                     /gene="thiE"
                     /locus_tag="ACHBV5_001258"
     CDS             complement(6446..7078)
                     /gene="thiE"
                     /locus_tag="ACHBV5_001258"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HFM9967052.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7071..7874)
                     /locus_tag="ACHBV5_001259"
     CDS             complement(7071..7874)
                     /locus_tag="ACHBV5_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HFM9967053.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLNYRPTVIKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEAYE"
     gene            complement(7874..8398)
                     /gene="thiW"
                     /locus_tag="ACHBV5_001260"
     CDS             complement(7874..8398)
                     /gene="thiW"
                     /locus_tag="ACHBV5_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HFM9967054.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(8403..9095)
                     /gene="tenA"
                     /locus_tag="ACHBV5_001261"
     CDS             complement(8403..9095)
                     /gene="tenA"
                     /locus_tag="ACHBV5_001261"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HFM9967055.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9106..9756)
                     /locus_tag="ACHBV5_001262"
     CDS             complement(9106..9756)
                     /locus_tag="ACHBV5_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HFM9967056.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(9758..11143)
                     /locus_tag="ACHBV5_001263"
     CDS             complement(9758..11143)
                     /locus_tag="ACHBV5_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFM9967057.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11144..11704)
                     /locus_tag="ACHBV5_001264"
     CDS             complement(11144..11704)
                     /locus_tag="ACHBV5_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFM9967058.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(11966..12054)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12263..12892)
                     /gene="thiE"
                     /locus_tag="ACHBV5_001265"
     CDS             complement(12263..12892)
                     /gene="thiE"
                     /locus_tag="ACHBV5_001265"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HFM9967059.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGAITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(12894..13676)
                     /gene="thiM"
                     /locus_tag="ACHBV5_001266"
     CDS             complement(12894..13676)
                     /gene="thiM"
                     /locus_tag="ACHBV5_001266"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HFM9967060.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEIAEKRPNGHLPGTFKAEFINALYEITDEDVKEFKRVK"
     gene            13779..14006
                     /locus_tag="ACHBV5_001267"
     CDS             13779..14006
                     /locus_tag="ACHBV5_001267"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967061.1"
                     /translation="MKIKEQTRKLTAGCSKHCFEPVDKTDEVSSKHCFEVVDRTDEVS
                     NHTYGKVKLTLFEEIFEESYLIKFVNIMSLL"
     gene            complement(14003..14671)
                     /locus_tag="ACHBV5_001268"
     CDS             complement(14003..14671)
                     /locus_tag="ACHBV5_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HFM9967062.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYNV"
     regulatory      complement(14886..14974)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15228..16364)
                     /gene="lctO"
                     /locus_tag="ACHBV5_001269"
     CDS             complement(15228..16364)
                     /gene="lctO"
                     /locus_tag="ACHBV5_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HFM9967063.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(16989..18479)
                     /gene="lysS"
                     /locus_tag="ACHBV5_001270"
     CDS             complement(16989..18479)
                     /gene="lysS"
                     /locus_tag="ACHBV5_001270"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFM9967064.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINKPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(18619..18753)
                     /locus_tag="ACHBV5_001271"
                     /pseudo
     CDS             complement(18619..18753)
                     /locus_tag="ACHBV5_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            18786..19046
                     /locus_tag="ACHBV5_001272"
                     /pseudo
     CDS             18786..19046
                     /locus_tag="ACHBV5_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc.;
                     incomplete; partial in the middle of a contig; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
     gene            19026..19703
                     /locus_tag="ACHBV5_001273"
     CDS             19026..19703
                     /locus_tag="ACHBV5_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFM9967065.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSVIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTTSFWIYGTILILYFAVCYPISKLSTH
                     LEKHWRN"
     gene            19704..20462
                     /locus_tag="ACHBV5_001274"
                     /pseudo
     CDS             19704..20462
                     /locus_tag="ACHBV5_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            20474..21334
                     /locus_tag="ACHBV5_001275"
     CDS             20474..21334
                     /locus_tag="ACHBV5_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM9967066.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDAAK
                     ADDLVVEGGH"
     gene            complement(21414..22061)
                     /locus_tag="ACHBV5_001276"
     CDS             complement(21414..22061)
                     /locus_tag="ACHBV5_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9967067.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKPGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(22058..22756)
                     /locus_tag="ACHBV5_001277"
     CDS             complement(22058..22756)
                     /locus_tag="ACHBV5_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967068.1"
                     /translation="MGKLSSYMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(22766..23518)
                     /locus_tag="ACHBV5_001278"
     CDS             complement(22766..23518)
                     /locus_tag="ACHBV5_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967069.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(23518..24282)
                     /locus_tag="ACHBV5_001279"
     CDS             complement(23518..24282)
                     /locus_tag="ACHBV5_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967070.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
BASE COUNT         7523 a         5265 c         4384 g         7151 t
ORIGIN      
        1 agttctgctc tatgaaaatc aaagaataaa gtctacaagt ttcatatttg attttcggcg
       61 agaggaatta tttaattgcg cgtgattgca atccttcttc ttccaagaag agacggaatg
      121 gtacgagttc ttctgcttcg tatttttcct tgaaggcttt gatagcttct tctgagtgaa
      181 gttttggatc caattcaagt acttctactg gaagtggacg gtgttgagtg atgcgagcat
      241 cgatgacaac agttttacct tctttgttca atttaacagc ttctgcaaca actgcatcga
      301 tgtcttcgat acggtcaact gtgaatccaa cagctccttg agcttccgca attttagcgt
      361 agtcagcgtt tgtgaagtct acaccaaaca agtgtttgtt tgtatcttcg tatttgttct
      421 tgatgaagcc gtactcagca tttgagaaga caaggttgat aactggaagg tcgtattgaa
      481 cgtttgtgat aacgtctggg tagcacatgt tgaatgctcc gtcacccatg atgttccata
      541 cttggcgatc tggattgtct ttcttagcag cgataccacc aggaagggca atacccattg
      601 tcgcaaagag tggagatgta cgccacatgt tcttaggtgt catgtgaagg tgacgagtag
      661 atgtttgagt agtgttacct acgtcgattg agtagatagc gtcttgatca gcatgtttgt
      721 tgattgcatt gtaaacttga tacaattgca attcaccctc agttttacct tcgagtttgt
      781 tcatgtaatc acgccagttt tggttgttct taacgtttgc acgccaccat ggagttgatt
      841 caactgggtt tactttgtca aggatagctt tagctgcttg accagcatca ccaaggattg
      901 aagcgtcaag agcatgacgt ttaccaagtt tgtaagggtc gatatcgact tggataaatt
      961 tttcagtgtt cttgaatgct tcgtaaactt cagcgaatgg gaagtttgaa ccaaggaaaa
     1021 gaactgtgtc tgcttcaaag accacttcgt tggctggttt ccaaccaaca cggtaagcag
     1081 aacctgtcaa accttcatag ttccattcga aagcttcaaa gtttttacca gttgtgatga
     1141 ttggtgcttt gattttacgt gacaattcag taatcacttc accagcttta acaccaccaa
     1201 atccagcata gataactggg cgttcagcat tgttcaagat ttcaacagct ttgtcgattt
     1261 caacttcgtt caaagcagga gcgatgaatg agcgttcgta tgaacctgaa ccgtagtatg
     1321 agttttcatc gatttcttgg aaaccgaagt ttactggaat ttcaacaaca gctggacctt
     1381 ttttagaaac tgcagcacgg caggcttcgt caattacttt tggcaattgc tcagcgtaag
     1441 ctacacgttt gttgtaaaca gcgataccgt tgtacattgg gttttgatta agctcttgga
     1501 aagcatccat gttcaattcg ttaactggac gtgatccaag gatcgctagg aatggagtgt
     1561 tatccatagc tgcatcgtaa acaccgttaa tcaagtgagt cgcacctgga ccacctgaac
     1621 caactgcaac cccgattgag ccgccgaatt tagcttgcat aaccgctgca agagcacctg
     1681 tctcttcgtg gcgaacttgt aagaaacgga tatctttgtc ttcagccaaa gcatccatca
     1741 atgagctgag tgttcctgat gggataccgt agattgtatc tacgccccat gttttcaata
     1801 cgttaagcat tgctgcagat gcagtaattt tcccttgagt cataatgata actctccttc
     1861 aattttttta aacttggaga atacgattac atagaattgg aaacgttctc caaattttta
     1921 ctattccact gtatcatatt tatgctgact tttctaaaaa tctgctcaaa actctctatt
     1981 ctctattcta atacagtttt gaaagtgttg tcgtttctgt tttataacaa agaaatctag
     2041 tcattacttt tagtctattt tactaaaatt taacagaagg gaactggtca gaacagatac
     2101 agaactaaag gccatggcta gacctgccaa ttctgggttg agagccagtc caacacctga
     2161 aaagactcct gctgcaatcg gaattccgac aacattgtag ataaaagccc agaaaagatt
     2221 gagtagaatt cgatgaaagg ttttcttact catatcaaag gcacgaacca ctcctaaaag
     2281 attattggtt gtcaacacca aatctgctga ctcgatggcg atatctgttc cagcacccat
     2341 agcaattccc acatctgcta cactaagggc aggagcgtca ttgataccgt ccccaacaaa
     2401 ggctactttc cctgactgtt gcagtttatg gatttcatgg gctttttctt ctggcaagac
     2461 gcctgcaatg acctcttcaa ttccgatttg atctgcaata gcacgcgcca caccagcatt
     2521 gtctcctgtc agcatgactg ttcggagacc acgttttttt agctgactga tggctagctt
     2581 agcattttcc ttaggaatat cttgcaaagc aagcaagcct ttgatttcat tgtcaacagc
     2641 taagaacaca actgtcttag cttctttttc tagttcttct agtttatctt gataagtatt
     2701 agaaatatcc atgccatcca gcattttagc atttccaagt aaaacttgtt ttccattgat
     2761 tcgccctgaa acacctttcc cgtgcaaggt ctgaaaattt tcaacagttt gaaactcaag
     2821 tccagcttca ctcgctcgct taacgatagc ctcagccagt gggtgttgag aagcatcttc
     2881 caaggaggct gccaacccaa acacttctac ttcgtcgccg atgacatctg ttaccacagg
     2941 tttcccttcc gtcaaagtcc cggtcttatc aaagacaagg gtttgaactt tctggatttc
     3001 ctgtaagaca gttccatttt tgaggagaac ccccatcttg gcactacgtc ctgtccccac
     3061 cataagggct gtcggtgttg caagtcccaa ggcacaagga caggcgataa tcaaaaccgc
     3121 cactccgtag agaagagagg acacaaagct agctccaagc acaaccacac tatccctgag
     3181 caagacgaac caaacccaaa aggtcatgat tcctaaaatg acaactactg ggacaaaaat
     3241 ccctgaaatc ttatccgtca agtcctgaat cggcgcacga cttgtctgag ctttcttcac
     3301 aaaatccaca atctgagcca aaacagtctc tgagccaact ttttctgctc taaagacaag
     3361 cgttccacta tgattgatgg ttgagccaat gacagtatct ccaactgtct tgtccacagg
     3421 cagactctca cctgtcacca tggattcgtc aatactagag acaccttcta ctacgacacc
     3481 atcaacagca atcttttcac cgggacgcac tcgaatcagg tcgcctacct tgacttgttc
     3541 caaaggaact tggacataac tatcatcact caagacttct gcggttttag cttgcaagtc
     3601 cagtaatttc tccacagctt gggacgtatt ttttctcatt ttttcctcaa aaactgctcc
     3661 caaaagaacg aaaaagagga taaatccagc actttcgaag taaacaggga gaccagcaaa
     3721 gagagcaact aggctataga aataagccac tagagttccc agcgcaacca aggtatccat
     3781 gttggcattg tgctttttaa aactggccca agcactctgg atatatggct tacctgcaac
     3841 taacataata ggcgttgttg ctagaaaggt tccccaatgc atgacttgat gactaatgct
     3901 acctgtcaac atcccaatca tgagaatcac aagaggcaca gtaaagatac tagtaatcca
     3961 aaaacgttgc aggagagata gagattttcg agtcttctca acgactgtat agcttccctt
     4021 ttgcatcttc atgccacaag aaaattcatg tcgccctaat tcttgaggtg taaaacgaat
     4081 gactttctcc tcatctacgc cgattggttc caagatacct tcttcttcaa acagaatttc
     4141 cttataacag tttgaaggag tagcacgatg aaaggtaatc tcagctggaa ttcccttttg
     4201 aagctggata tgggctggat gatagccttt ttcagatcgg atacggattt tttgaatgcc
     4261 attttctaag cttgctttca caatttctgt catagtctcc acctactcta caatcatctt
     4321 gccgtgcatc atgttcatac cacaagcaaa gccaaattct ccagcctgtt caggcgtgat
     4381 ttccactaca tactcttccc ccattggcag gttcgtatgt acaccaaaat ctggaaaaac
     4441 aatttgatcc agacatggtg aaggatcctt gcggtcaaag acaatgcggg ctggcactga
     4501 tttcttgagg acaatcaact caggagtata gcctcccatg acttccactc gaatctcttg
     4561 gtatccgttt ttttgctggg ctttttgtcc agatttttca ggctttttga aaaaccaaaa
     4621 caagataaac gcgataaggg caatacaaat aatggttaca atactattta acatgacgtc
     4681 tcctttacat acaattacat cttacttctg ttacagcact tgatttcttc tctgaaatca
     4741 cagcttccaa gtcttccaag tcagtctgag taaattcaca ttctacaatc aagtcagcca
     4801 acaaattcct aatcctacgg gaacaaacct tgtctttgat atcttggaca agtaaatccc
     4861 gactttggtc tagagttaaa agggctgaat aaacaaagga cttgccttct tttttccgag
     4921 tcaaacactc tttctcaacc agacgagcca aaagtgtctg aaccgtggac ttggaccagt
     4981 caaaccgctc tgccaaaacc ctaatcaaat ctgtactggt ctgctccccc tgcatccaaa
     5041 taatcttcat gacctgccat tctgcatctg aaatctgcat taccatacct ccaaaatcta
     5101 catttgtcaa ttacactcat cagtatactc ttaaaatcta catttgtcaa ttatagaaat
     5161 aatattttct tcgaaaaata gaattttaat catttgaaaa acgatttgca gtcaaatatt
     5221 actatataaa caataaaaat atgctatact aaagaaaaaa gaaaacaacc actaggggtg
     5281 cgtaaagctg agattaacga ctgttagatc cctctgactc aatctaggta atgctagctg
     5341 atggaagtgg aaatgataat ggggactagc agtcttctat tgcctttcta aaacagacta
     5401 gcttgttctt aagaatacaa acttcagttg gttgggaggt tttagatgac ttatttaccc
     5461 gttgctttga ccattgcagg gactgaccct agtggtggtg ctggcattat ggcagattta
     5521 aagtcattcc aagcgaaaga tgtctatgga atggctgttg taaccagtct tgtcgctcaa
     5581 aataccagag gtgttcagct aatcgagcac gtttctcctc aaatgttgaa agcccaattg
     5641 gagagtgtct tttctgatat tccacctcag gctgtaaaaa ctggaatgtt ggctactact
     5701 gaaatcatgg aaatcatcca accctatctt aaaaaactgg attgtcccta tgtccttgat
     5761 cctgttatgg ttgctacaag tggagatgcc ttgattgact caaatgctag agactatctc
     5821 aaaacaaact tactacctct agcaactatt attacgccaa atcttcctga agcagaagag
     5881 attgttggtt tttcaatcca tgaccccgaa gacatgcagc gtgctggtcg cctgatttta
     5941 aaagaatttg gtcctcagtc tgtggttatc aaaggcggac atctcaaagg tggtgctaaa
     6001 gatttcctct ttaccaagaa tgaacaattt gtctgggaaa gcccacgaat tcaaacctgt
     6061 cacacccatg gtactggatg tacctttgct gcagtgatta ctgctgaact agccaagggc
     6121 aagagtcttt accaggcagt tgataaggcc aaggccttta tcacaaaagc tattcaagat
     6181 gcccctcaac tcggtcatgg ttctggtcca gtcaaccata caacttttaa agattaagaa
     6241 aaaaactctc tagttcccac tttaagggaa ttagagagtt tttataccct tcgaaaatct
     6301 cttcaaacta cgtcagcttc catctgcaac ctcaaaacac tgttttgagc tgacttcgtc
     6361 agtcttatct aaaacctcaa ggcagtactt tgagcaacct gcgactagct ttctagttta
     6421 ctctttgatt ttcattgagt attaattagg aaagaatgtc atgcaacttt gttaaaaagg
     6481 cttgcgtttt tgcctcaata tcttctgctt gcatcaaatc acgtacaaca gctacaccag
     6541 ctatgccagt gcccataagc tgatcaatat tctccgaagt caagccgcca atagcaacta
     6601 ttggaatggc aaccgtttgg caaattgttt tcaaggttga aatcagggtg atgggtgcat
     6661 tttccttggt ggttgtcgga aaaatggctc ctgtccccaa gtaatctgca cctgatttct
     6721 ccgcttccag agctctttta accgttttag cggtgacacc gaggattttt tcaggaccca
     6781 agacttgtcg ggcaaccgaa actgggagtt cgtcatctcc aatatgcaga ccagcagcat
     6841 caaccgcaag acaaacatcc aaccgatcat cgattatcaa gggtacctga taggcatctg
     6901 ttatttcctt gacttgtttt gccagttgat aatattgatt ggttgtgaga tttttttctc
     6961 gcaattggac tatggtaacc cctgaacggc aggccgtctc aacttttgca agaaagcttt
     7021 ccacggaatc ttgatagcga ttggttacca gatatagtct aagtgcttct ctattcataa
     7081 gcctctcctt tgatggtatc tagccaattt tcatctcttc ttaggagcga aagctgattg
     7141 agtacttggt aacgaaattc ttccaatccc attccttgaa caactatttt ctcagcagcg
     7201 atattgagat aagagactgc taagcaagaa gcttcaaaac cagtctttcc ttggctgaga
     7261 aaaacggctg ttaaggctcc aaccaaatct cctgtccctg ttatccagtc taattcagta
     7321 cagccattct ccagtacagc gacctgattt ttcgaaacga tgaggtcctt ggggccagta
     7381 actaagaatg acataccagg ataggtctga caccagtctt tcaagacttg aagcaaatcc
     7441 tccgtttctt gatctttagc actcgcatcg accccaacgc cgtggtgctt taagccaaca
     7501 agacttcgaa tttctgacat gtttccttta atgaccgtag gtctatagtt taaaaggtct
     7561 ttaactaagc tcttacgaat ggatgaagtc gttacgccaa ccgcatctac taccatcggg
     7621 agagaagatt ggtttgcata cgaagctgcc atgcggattg ctttttcctt ctcagctgac
     7681 aaatgcccca aattgatgaa aagagcctga ctttgcttag taaaatcaag aacctcacgg
     7741 ggatcatctg ccatgacagg tttgcatccc agagccaaaa tcccatttgc cagcatctca
     7801 caagaaatct cattggtcat acagtgaatt agggaactag agcctatagg aaagggattt
     7861 gtaaattcct gcatcagtct atcctttcac taaagaaata tccctgcact tttttaaaga
     7921 attcctgctt gattaaaaat cgaaaggcaa taaaggaaat cgctgtacca atcaaggttg
     7981 ctccgaaaaa tcgaggcgtg tagataaacc agctaagctt agcagctgat cctgtaaaga
     8041 gtaccataac aggataggaa acaatggaac caataatacc tgttcccaca atttctccca
     8101 aggcagaaaa ataaaatttt cgaccgtact tataaaagag acctgccaga agggctccaa
     8161 aagtcgctcc tgtgagagct aaaggcggaa tcccttgagt cgtcatacgg ataaaggctg
     8221 tgactgtagc catggccaag gcataaacag gtcccatcat gattcccgct agaatattga
     8281 ctacactgga catcggtgcc attccctcaa ttcgaaagat aggtgtaagg actacatcaa
     8341 gggcaatcat catagataaa atggtcaatt tgtgaacttg tagttggtgc tttctcatgt
     8401 ttctattctt ctcctttttc taaagactgt aaatcgctct tccatgtctg gtgttggtaa
     8461 gccatctccc aaaacttggc ttccatatga acactgatgt ggaaggcatc tagcattttt
     8521 tgcttatctg tctcatcact ttctcgatag agctgattga ccagtgctcc ctcctctctg
     8581 atctgttgct ctaactcatc cgtaatataa gtttcaatcc attgttgata gagaggattt
     8641 ggtgatggtt taagattaag tgatttgcct atatcatggt ataaccaagg acaaggaagc
     8701 aagcttgcaa aagctatggc taagttcggt tctgcaaatt gcctataaat atgagaaatg
     8761 taatgataac aggttggagc aattggatgt tgctccattt cctggtcgct gatttccatt
     8821 tccttgaaaa attgttggcg aataaataac tcaccctcca ctaaaccctg agcattttgt
     8881 ttcaagagtc ttttcatctc ttggtttgaa gtcttatcag ccaaaagatg atagatttct
     8941 gagaaggcct tcagatagta ggcatcctga atcaggtaat agcggaaaat ggcaggttct
     9001 aaattcccct cttgtaattg taaaataaag ggatgatgaa aggaagcctg ccaagctttc
     9061 ttggataatt ccatcgcaat atctgtaaat tccataataa ctcctttata aaaatagact
     9121 ggtttgaagc aataaaaaga aaagcaggta gattaatttt gtttttttag gaatataaaa
     9181 agtccgatag ctattcttca actgtgcatg ttcgtcatat ccatgagcag acagagctct
     9241 caggtaaaga tggcgccacc taaagactgt catcagaacc ttactgtaaa tcaagggcga
     9301 ccaaaaatgc agttcttgac cacgtaatag gcaagcttct ttgagggact tgatttcttg
     9361 ctgaatgaga ggaaaggaat tgaataccac aatcaaggca taggaccaag agcgtgatag
     9421 ccccttttga gccaagtaca agagaagctc ttttagtgaa atagaggaaa caaagacaag
     9481 gccgatacaa actgtcacaa aggccctcgt tccaagcatg actgcctgtg aagcatctcc
     9541 gtgtaactga actgcccagt agttggcaaa agatggtaaa atggcaagta tgatcatcca
     9601 agctaacatt ttaaatcgac ggtaatagag cataaagaga atacaaaatg cgactaccga
     9661 aagattcaga gcaatcgaag gaatgaaaga tgtttccaag gataaaatca gcaagaagag
     9721 actgataatc ggtgtctggg ttgctacttt gaccatacta tctcacctcc ccttgggtat
     9781 tgctactctg agatgtaagt ggtttggtaa tggtcacttc tttcacatgc cgaagaccct
     9841 gactagtcat ctcaatccaa taatcaacca cagaaatcaa agggtctaaa cgatgactaa
     9901 tgagcagaaa acttcttcct tgattcctct cctccacaat ccacttgcaa aaataatggc
     9961 aggctctatc atccaaacct gcaaaaggtt catctagcaa gatcacggaa gccttactgg
    10021 tcaagatggt caagagctga agaatttttt gctgaccacc acttaattga tagggactct
    10081 tatcgactgc ctgctccaaa tcaaaatatc gtaaagcttg aaaaatccgc tgatttcttt
    10141 cagaatcagg tccatctaat tgaagctcct ctcgcagact gactcggata aactgcttct
    10201 cagcttcctg aacaacacca gtcagatcac gatacaaact ctttttcttt ttcaggactg
    10261 tccccttcca tgcaatgcgc cccttatact tttgaaattg aagaatagag cgaaagaggg
    10321 ttgatttccc gacaccattg tcacccagga tacaggaaat cccttgatag aatgtgaaat
    10381 cagcaattga aaagaggggg cgattaccaa gctcaccagt cacacggttc atatggaata
    10441 gttccgggct agaagcaact tcctttgaag caacctgtgt catctcatag gaagggattt
    10501 gaaacacttc ccttagtttt ccgtctctta gctcaaccat atggtcgata taggctttat
    10561 agtcagataa atcatggtcg cacaaaataa ctgtcttccc atcaagagcc aactctttta
    10621 gaatctccaa tatctcgatt ctgctcttgc ggtcaataga agcgaagggc tcatccaaga
    10681 gatagaccct aggattcatg gcaaagagga cagccagcgc tgctttttgc ttttccccac
    10741 ctgataggtg atgaatggga cggtgtaaga ttgcctcgca acgacattgc tggacaacct
    10801 ctgctatttt agaatcaatt tcctgaaggt gatagccgat attctccaag gtgaaaatca
    10861 gctcctcaaa caagttctcc atggtaaatt gatgattggg attttgaaag agaatgccaa
    10921 ccttctggac acgtgcgatg atagaaagct gactgacctc gctcccatct atcaggactt
    10981 gaccactata gggaagagaa ctgacttggg caatgacttg aaaaaggctg gattttcctg
    11041 aaccactgct cccaactaac aaggtaaagg cttgcgcatg aaaagtaaaa tcaaacggct
    11101 cagagaagat tggggactga atcgctcgta gttccagacc catctatgct tttcctccag
    11161 ttgcaaactg atgatagagt ttgacaatgg cacgaaccaa gatggtacag aagaaataaa
    11221 cagaaataaa acgtaccaca agtaaggaaa ggacaaacgg aagggaaaag gcgtagtaac
    11281 ctaacttaat gtattcatag acaaagctaa caagcgtaat cccaatacta ttagcagtta
    11341 gagagagcca actttcatag cgattcttag ttacgataaa accaaattca cttcccaaac
    11401 cttgaaccaa gccagacaaa agagctccta gaccaaattg gctaccataa aggacttcag
    11461 caagcgcagc tagcacttct ccaatcgttg cacttccgac tctcggaaca aagatggcag
    11521 caatgggcgc agccatacac cagagaccga agaggatttc attggcaaag gcctgcaaac
    11581 caagaggtgt taagagtaga ctgagaatat tatacacata tcctgaacca acgaaaaccc
    11641 caccaaaaaa gatagacaag aaagcaagca agataacatc ttttaactgc cattttttca
    11701 acataaaaaa ctcctttttt aaaagaaaag tggggcactc aagaagaccg acctaaatac
    11761 tttgtatagc agattgaatt tagaacagta cacaggaatg ctaaaatatt tctagaaatt
    11821 aatttgaatt ttctaattga tttgttcgca tcttatttca atctactata tcatcttcat
    11881 ccagtttcgt aaaagaaaaa actctaatta cagatacgaa ttagagttca gcttacaaga
    11941 ttagacagtt cttttcgaca tacgaaaaaa acatttcaca tttcccttcg ccagtcttaa
    12001 ctgtatcagg ttcaatgggt atcatctcag cctaaagcac cccaaatgcc tttattattt
    12061 aattatgtga ttattataac acacatttta tactagttca agaaattgaa ctggaaatac
    12121 agccttgcac tcacaaagac agcagatctt tcttttgcaa aaaacaaatg acctgtttga
    12181 tgaattagcc attcaagctg aatctagaca tagcttttta aaaaaggaaa atcctactta
    12241 cttagaatcc aaggatagat atctattgtt cactcatttc ccgaacagtt ttttctatat
    12301 tttttgcata cgatattgcc gaaatgattg aaacgccgtc aacattggtc tttataatgt
    12361 ctttaatatg tttcgtctgt atcccaccaa ttgcaactaa aggcatttgt ggcaatagtt
    12421 ttctcatcaa ttcaagacct tcataaccta tagcaccacc agcatcatct tttgactggg
    12481 tatcaaatac aggcccaaca cctacataat ctacatattc aacttttgat tgttgaaatt
    12541 cttcttcgtt tcttatagaa agaccaatta ttttatctgg catcaatttt ctaatttcat
    12601 caacaccaat atcatcttga cctacatgta cgccatcggc gtcaatttcc attgctaaat
    12661 ctatatcgtc attaacgata aatggaacat tgtatttttt acaaagttct ttaatttgga
    12721 tagctagctc aagtttttct aagccttcta aagcaccctc acctttttct cgaaattgaa
    12781 ataaggttat agcacctttt aaggcttcct caacgactgt atatagattt tttccttggc
    12841 aagtagtcgt tccacaaata aaatatagtt ttagtaattc tttatgaaac atcttacttc
    12901 actcttttga attcctttac atcttcatct gtaatctcgt ataaggcatt tataaattca
    12961 gctttaaatg ttccaggaag atgtccattg ggacgttttt ctgctatttc tccagcgata
    13021 ttgtaaacca acattgctgt ttctaatgat ttcaattctt gacctttttc tagtccgata
    13081 aagcttgcta ctacagctcc taataagcat cctgtcccaa tgactttcgg catcatagca
    13141 ctaccattat gaatcgttac cacttctcca ttaacagcaa tggcatccac ttcacctgtt
    13201 actactattg gaatattgaa cttctcattt gctgctagag caatttcgtc aatattatct
    13261 acgcccgcac tatctactcc tttagatgcc acatctattc ctactaaaga ggcaatctcg
    13321 ccagcatttc ctctaatcgc tgctagttta taattgttga ttagatcatc cgctactttt
    13381 tttctatatt ctcctgctcc acaggctaca ggatctaaaa ctgctgggac attatatttc
    13441 tccgcaattt tcagagcagc ttggtataat ttccaatttt catctgtcaa tgttcctatg
    13501 tttattaata aaccaccagc atactttaac aaatcctcta aatctgctgg aaactcactc
    13561 atggctggtg aggcgcccag tgctactaat ccatttgctg tgaaattttt tactacatca
    13621 ttggttatac aaatgaccaa tggtgctttt tcttttaata attttaaact tgtcatattg
    13681 aaatccttcc ttttcacttt atacgatcta ctgatttcga tttatatcta tctttcgtta
    13741 agaaattttt ttcatttaca ttgaatgatt tatactcaat gaaaatcaaa gagcaaacta
    13801 ggaagctaac cgcaggttgc tcaaaacact gctttgaacc tgtagataag actgacgaag
    13861 tcagctcaaa acactgtttt gaggttgtgg atagaactga cgaagtcagt aaccatacct
    13921 acggcaaggt gaaactgacg ttgtttgaag agattttcga agagtcttac ctcatcaaat
    13981 ttgtaaatat catgagcctt ctctagacat tgtaaccaat atcaaaaaaa gctaattcta
    14041 aagcgactgc ttgattccag cgttgctgaa gttctgtcaa atcttctcga tttttaccga
    14101 cacgattgag ttcgtcaacc agaaattgaa cccactctgc aaagaaagga cctctgtgga
    14161 gattgatcca ttccgaatga atatagactt caggtagagc caaatcttta gaaccccagt
    14221 ctaaatagag accttctgca atgaccagca taaccaaaag atgggcatag tctgatgaag
    14281 ccactgccga atacattaga tcctgaaagg cttttgttac agggtgcaaa gtcacttcta
    14341 gatagtcatt ctctgctact tttaactctt taaaagcctt ttggaaataa ccatcttcat
    14401 ctgcttcaag aaagcctagt tgcttggcaa aacgaagctt ggattcaagt ttatctgcgt
    14461 gagctacgca ggcacccagc atggataaga aggcatcaaa gaagtgataa tcttgaatca
    14521 gatagtcctt taagacctta ttctcaattg tccccgcaaa aagttcctta acaaaacgat
    14581 gattgattgc agcctgccaa tccttctgac tgctttttaa taattctcca acagtcaaac
    14641 ctggctgaaa tgcatagtct tgtgtttcca tatttacttc tcctctcttt acttgttagt
    14701 aattaataaa acaccaagaa atatcaagca aaatcgtaat tccacttgat ccttttaaag
    14761 cacatcgaga gcatttgcag agagctaact aaacaagcct atccagttta tataaacaaa
    14821 aaactccaat tacaatcaag aattagagtt gacttacaag attagaccgt tcatttcacc
    14881 atacgaaaaa actgttcaca tttcccttcg ccagtcttaa ctgtatcagg ttcaatgggt
    14941 attatctcag cctaaagcac cccaaatgtc tctattattt aattactgaa ccagtatagc
    15001 aaaaaatgaa agccctagca agatatttga ccgaaaaata tctttatata taatatattg
    15061 aaactagaat agtacacctc tacttctaaa acattgttag aaatcgattt aactgtcctg
    15121 attaatttgt cctattctta tttcatttta ttatagtttt cgatagcgat ttattcttcc
    15181 aatacacgaa gaaaaacctc cacattcagt ggaggcaatc tgttttatca atacaatttt
    15241 aagtcacgag ggtcaactgg gaaggttggg ttgtatggat tgtgacggag cttaaagtgt
    15301 ttgacatctt caatggtctg agctccagac aattgcataa ctgtcttcaa ttccgcattc
    15361 aagtgttcaa agacttgacg cacaccgaca ctaccaccga gagccaagcc ataaataaca
    15421 gggcgaccaa tagctaccaa gtctgctcct gaagccaagg ctttaaagac gtgttgacca
    15481 cgacgaacac cagagtcaaa gacaatcggc acacgtctat caactgcttc tgccacttct
    15541 tgaagcgagt caaaggcagc tggtccaccg tcgatttgac gaccaccgtg gttggttacc
    15601 cagataccag aagctcctgc agcaagtgaa cgttcaacgt cctcacggca ttgtggtccc
    15661 ttgacataca caggaagacc agagtattca gcgataaatt ctacatcgcg tggagacaag
    15721 cgttgtttag ctgatttgta aacaaagtcc attgatttac cagcaccttc tggcaggtat
    15781 tcttcaacaa tcggcatgcc aactgggaag acaaaaccat tacgcttatc cacttcacga
    15841 ttccccccta cagtagcatc tgccgtcaag acaatcgctt tataaccttc agccttcaca
    15901 cggtccatga tgtggcggtt gataccgtca tccttactaa agtaaaattg aaaccaatga
    15961 ggtgtccctt gaagggcttc agaaatctct ggaaggtcaa cagtagagta agaactggtt
    16021 gtataaagag aaccaaactc atgcacacca cgcgcagtcg ccacttcccc ctgttcattc
    16081 gctaatttat gggccgcaac aggcgccata atgattggtg aagatagttt ttcacctgca
    16141 aattcaatct ctgtacttgg attttcaaca tcgcaaagtg tatgaggaac gatgagtttg
    16201 tggttaaagg cgcggatatt ctctcttaaa gtgaaagtat cttccgcccc actagcgata
    16261 tagccaaatg ctgctttagg aataacttgt tgcgccattg gctccaaatc ataggtattg
    16321 atgaagtcta catgaccttc tgcattgctt gttttgtatg acataaaatg ccctccttga
    16381 ttaagtaagc gtttgctttt tactacacaa ctataataac tcttttttca atcattttca
    16441 agagttttgc ttaaaaacca tcttattttt tcatacaata tactagccct actttcctta
    16501 aactctaaac tttagtctat attaagtgaa tcgttgagat tttttgctgc caggcatttg
    16561 aactactttt ttatttgcgg attctatcta ctaatactat aaaaaaacaa gtgaataaga
    16621 caccagaaca tcctctaata ggacctatgg acttatatca gtcccatata tactgtttaa
    16681 gcaagatact atcctagttg acgctaactt cctatcccac ttattaattt tttatttata
    16741 gtgaatctga acaaatcaat tgggaaatcc aagtcaattt ctagtacttt ttgaacagtt
    16801 tcagcgtact atcgtaaaat gaaataaaac atgcacaaat tgattaggga atttaaacca
    16861 atttctaaca gtgtcttaga aatcaaagtg tactatttca acttcaatat actacacttc
    16921 attttctcct taaattcagt ctctttttga atcaaaaaat cccctggtaa gagccagagg
    16981 gtaagaattt atttcattgt tgggaagagc aatacatcac ggatagttgt tgtatcagtg
    17041 aggagcatgc agagacggtc gataccgatt cccaaaccac ctgttggtgg cataccgtat
    17101 tcaagagcct cgatgtagtc atagtcgatg cctgtcgctt catcatcacc aagttcttta
    17161 gctttagctt gggcttcaaa acggctaagt tgatcgattg ggtcgttcaa ctcagtaaag
    17221 gcattaccgt actccttagt catgataaag agctcgaaac ggtcagtaaa gcgttggtct
    17281 tcaggatttt tcttagcgag tggagataca gctactggat gtccatagac aaaggttggt
    17341 tggattaaag tttcttcgac aaactcttca aagaaggcat tgatgatgtg accaacctca
    17401 gtgtagtgtt tctcaactgg aactttcttc tcagcagcga tagctttagc ttcttccaaa
    17461 gtcatgtctt gccagaaatc gacaccagta atttctctga tagcatccac catatgaaca
    17521 cgcttaaatg gtttgttaat cttgatttca gtaccttggt agttgactgg gccatcacct
    17581 ttgactgatt tagcagcgtg ttggataatg ccttccgtca agtccatgat gtcttggaaa
    17641 tctgcataag cttggtaaac ttcgatagaa gtaaactcag ggttatgagt agcgtccatt
    17701 ccttcgttac ggaagatacg gccaatttca tagacacgtt ccataccacc cacgataagg
    17761 cgttttaagt gaagctcagt cgcgatacga agcaccatgt caatgttttg ggcattgtgg
    17821 tgggtgataa atggacgggc agcagcacca ccggcttcat tatgaagaac aggtgtttcc
    17881 acttcaagga atcctttttg gtcaaggtaa cgacggattt cagagatgat ttttgaacga
    17941 gtgacaaagc gttcaaagct ttcacgatta gaaatcaagt caaggtaacg tttacggtaa
    18001 attgtttcaa cgtctgtcaa accatggaat ttctcaggaa gaggacgaag agccttagac
    18061 aagtgtgtga tgtgggttgc cttgatagag agttctccca tatccgtacg catcacttca
    18121 ccttcgacac caaggaagtc accaaggtct gcttttttga agatttcgta gttttcttca
    18181 ccgacagcat ccttacgaac atagatctga atctggcctt cgcggtcttg aaggtgggca
    18241 aaaccaactt ttcctttacc acgtttggtt accaagcgtc ctgcgatagt agctgtttcg
    18301 tttttatcgt gtaattgttc tttatcgagg ttggcatatt tatcttttaa ttcttgtgaa
    18361 tttgcagtac gttcaaaacg ttttccgaaa ggatcgattc cttgttcgcg gagcgcagcc
    18421 attttttcac ggcgaacgat ctgctggtca tttagttctt ccatatgttc tgtagacatg
    18481 ggatcctcct agttttactc aaaattgaat acgatgagtc attttttgcg atacccccat
    18541 tttatcataa ataagcaaga aattcacgga taatctttaa aaactaaaaa gaacctgacg
    18601 ctaaaatcac tggaaagaag tgaaagtatc ttccgcccca ctagcgatat agccaaatgc
    18661 tgctttagga ataacttgtt gcgccattgg ctccaaatca taggtattga tgaaatctac
    18721 atgaccttct gcattgcttg ttttgtatga cataaaatgc cctccttgat aagtaagcgt
    18781 ttactttgta tattgcagtt tggggaagtt tgggatcctt tctgctcggt ttaatcgtta
    18841 gtatcatccg acattatcga atccctgttt tggcgcaagt agcgacagcc tacattgaat
    18901 tgtcacgtaa tacgcccctt ttgattcaac tcttctttct ctacttcggt cttccccgaa
    18961 tcgggattgt cctatcttca gaagtctgtg caacgcttgg gcttgtcttt ttaggaggct
    19021 ccgccatgca ggattcggga atccaagtac tctttcaagg aaataacctc ctgagaatct
    19081 tacagggatt gggcgttacg attgggatat ccatcctgtc tgtcctctta tccatgatgt
    19141 tcggaacagt catgggaatc atcatgacct cccattctag aatcatacga tttttaacac
    19201 gattgtatct ggaatttatc cgtatcatgc cccagctggt gctactcttc atcgtttact
    19261 ttggcttggc tcgaaacttt aatatcaata tctcaggtga gacttcagtt attatcgttt
    19321 ttaccctctg gggaacagct gaaatgggag acttggtacg tggagctatc acttctctcc
    19381 ctaaacatca gtttgaaagt ggacaggcac tcggcttgac taatgttcaa ctttactacc
    19441 acatcatcat cccacaagtc ttgagaagac tgctaccgca ggctatcaat cttgtcactc
    19501 ggatgattaa aaccacttca ttagttgttt tgattggggt tgtggaagtg accaaagttg
    19561 gacaacaaat catcgatagc aatcgcctga ccatcccaac tacttcattt tggatttatg
    19621 gaaccattct aatcttatat ttcgcagttt gctaccctat ttccaaacta tccactcact
    19681 tagaaaaaca ttggagaaac taaatgtctg aaactatctt agaaatcaag gaactaaaaa
    19741 aatccttcgg agacaatccc atcctccaag gactttctct agaaatcaaa aaaggggaag
    19801 ttgttgtcat cctagggcca tctggttgtg ggaaaagtac cctccttcgt tgcctcaacg
    19861 gcttagaaag tattcaaggt ggagatattc ttctggatgg tcagtctatc gttgaaaata
    19921 aaaaagattt tcacctagtt cgccaaaaga ttggcatggt cttttaaagt tatgaactct
    19981 ttccccatct ggatgtctta caaaacctca tcctaggccc tatcaaaact caaggatggg
    20041 acaagaaaga agtaacggaa gaagctttgc aattactaga tcgtgtcggt ttgctggata
    20101 aacaacatag ctttgcccgt caattatctg gtggacagaa gcaacgtgtt gcaattgtcc
    20161 gtgccctcct aatgcatcca gaaatcatcc tttttgacga ggtgactgct tcgctggatc
    20221 cagaaatggt gcgtgaggtg ctggaactta tcaatgattt ggcccaagaa ggccgtacca
    20281 tgattttagt aacccacgaa atgcagtttg cccaagccat tgctgaccgg attatcttcc
    20341 tcgaccaagg gaaaatcgct gaagaaggaa cagctcaagc cttctttacc aatccgcaaa
    20401 ccaaacgagc ccaggaattt ttaaacgtct ttgactttag ccaattcggc tcatatctat
    20461 aaaggagatt cttatgaaac tattcaaacc actcttaact gttttagcac ttgcctttgc
    20521 ccttatcttt atcactgctt gtagctcagg tggaaacgct ggttcatcct ctggaaaaac
    20581 aactgccaaa gctcgcacta tcgatgaaat caaaaaaagc ggtgaactgc gaatcgccgt
    20641 gtttggagat aaaaaaccgt ttggctacgt tgacaatgat ggttcttacc aaggctacga
    20701 tattgaacta gggaaccaac tagctcaaga ccttggtgtc aaggttaaat acatttcagt
    20761 cgatgctgcc aaccgtgcgg aatacttgat ttcaaacaag gtagatatta ctcttgctaa
    20821 ctttacagta actgacgaac gtaagaaaca agttgatttt gcccttccat atatgaaagt
    20881 ttctctgggt gtcgtatcac ctaagactgg tctcattaca gacgtcaaac aacttgaagg
    20941 taaaacctta attgtcacaa aaggaacgac tgctgagact tattttgaaa agaatcatcc
    21001 agaaatcaaa ctccaaaaat acgaccaata cagtgactct taccaagctc ttcttgacgg
    21061 acgtggagat gccttttcaa ctgacaatac ggaagttcta gcttgggcgc ttgaaaataa
    21121 aggatttgaa gtaggaatta cttccctcgg tgatcccgat accattgcgg cagcagttca
    21181 aaaaggcaac caagaattgc tagacttcat caataaagat attgaaaaat taggcaagga
    21241 aaacttcttc cacaaggcct atgaaaaaac acttcaccca acctacggtg acgctgctaa
    21301 agcagatgac ctggttgttg aaggtggcca ttaactctta aaagggactg gattttaagc
    21361 tccaatccct ttttaagatt ttacctataa catcctgagt ctatctaaga tgttcaatct
    21421 gaacacagtg tacatacttt atcttctatt gcatatactt tatcacataa gatacgaata
    21481 tcctcttcac tatgactagc aatcaaaatt gttgtccctt tttcactaga gagctttcta
    21541 aacaatgttc tcatattttc tacacttgat ttatccaagg cattcatagg ttcatctagt
    21601 aaaagaatag agggattctc cataattgct tgagcaatcc ctagcttttt cctcatacct
    21661 agcgaataag ttttaacttt ctggtctttt tgctcatata gaccaactat tttcagtgta
    21721 tcattgattt cctgattacc aactactcct cgtatgcttg ccaaatattg taaattctta
    21781 aagccactat aataatttat aaaaccaggt tcttcaatca aagctcccaa attagctgga
    21841 atttttctct caggaacaat attttcccca ttgattaaca cttctccata agacggacta
    21901 tataaaccag ctattaattt aaacaataca cttttccctg agccattcgc accagtgatt
    21961 cctatgattt cccctggttt acaactaaag ttaaggtttt gaaaaacaca tgtctttttt
    22021 aatttcaact caatattttt taatatgatt atttcattca ttctataaac ctcctctttt
    22081 gacgagtgaa atagaaaata cttttaaaaa gaaagactaa aaatagcaac tgaagaaata
    22141 aatctcgtcc tatatctcca ttccctcgat tcaaaatata aaatagataa ttagttcgat
    22201 tccctacaaa tagaccacca aacacaatca tgagtaaaaa gaaactaacg caagcaaagt
    22261 tcatttgtac attcgctcct agtgcgtata acataaagca aagcaaggat agcacacaag
    22321 cattcaaaga atcaactata aacaaaactc ctatatccca gtttggtaac tgtaacataa
    22381 attgaatcac tagaactttt accatgatta aaatgagtcc ataaagaaaa caggtccaaa
    22441 tctgatacct aatccagagc ttaatagaag aaaatcgaat cacttccata aagaaatcgg
    22501 atgctcttct acgatataca actgctagaa aaaatgtatg aataataaac caatgaagca
    22561 accatatgga taagactaaa aaagagtttt gactcagatt aggccctttt aaaatttcta
    22621 taacaagtct atcatttcct tctaaccaat accataatcc taaacaaatc aatatccaaa
    22681 aaagaacata accccaaaag tacttggtat agattatctg attcaacctc cacatgtaac
    22741 tacttaactt tcccatttcc aacttttaca ctctcctcca gtttctatga acagaaaata
    22801 cagtcaatgg aattatgata gatagtaatg taagccaata aatcaatgca tacggattgg
    22861 aatttaccat atactgaaaa attggcaata atccaattat cccattgtcc aactgataaa
    22921 tccagaataa ggattctaca aataaaaaag taaacagaaa tactaagctc atgtttgatt
    22981 ttttaaacca agaaaaactg ctaatagtaa gtaaggataa aaagaaatag tatgctatat
    23041 aagagaaaaa aaatcctata aagaaactag cattgtttgc aatacttata ccataaaatt
    23101 ctcttaaaaa atcaacctcc tttatctcca aagagaagct aaaaccatta ctaaatgcaa
    23161 ttagaaaaat caataaaaat aaagtcgccg tccaaatccc cgtactaaga gctgctaatt
    23221 tgaaactaaa actggtaaag tgcttaattg atttcagacg aatgcgacac tccaacctat
    23281 taaaatagtt attcatcaaa taaaaaaaga acaatatata tgtgaacgga aagcaatata
    23341 ctccagtcgt catatcttga agtaaaacta agatccattc taatacattt ggatggattg
    23401 aatattggcg acagcgcaat aaatatactg tactagataa aacacaggat agcagtaata
    23461 taaaataaac caatactgct aagaaatctt ttttataaaa ttgaacaaat tgtttcatta
    23521 tacgtagtcc tctgaatgta gaaaaaatgt accataaaca accaaacaac taacaaataa
    23581 aataaaagca agatgcccac taactaagga aagactgata tctttctgat atcccaaagc
    23641 taatgttgtc acaggttcta agtaagatag ccctaaaata gcccaaaaaa taccaccaac
    23701 catcatatag gcaactggga tgaaaatagc tcctattttt ttcttcacta gcaaagcact
    23761 agctagtcca aaaatagaga acacagcgcc ccaaactcca taccagagag tcgtcacaag
    23821 actatagagc aactgattag aatcaaataa ttcttttaag gcaccactat aatctccaat
    23881 ataaatttcc tgataaggag tcactaaaag attaattcct aataataata aataggggag
    23941 aaaaaagact agaaaagaag aaataattgc agtactaccc acaatagcta gatacctctt
    24001 tttagaaatt cggcacaatt gtgctgttag aaaatgactc tcagcatcct ctattatctg
    24061 actagaatag ggcagtgtac agataagtgc agctactagg ctaatcggtg aaaatcctcg
    24121 aatagaagaa gcggcaaaaa aaatcgataa accttcaatt ttataaatac cattgaaagc
    24181 aaggaaattt cctaaactca tgcaaagaag ggtcaaaaat aaagacatat aaaatcgagg
    24241 tgattgaacg actcgtacaa gattacaaat gaaaaattcc atccttactc ctccttataa
    24301 taaaaatagg gtgtagcatt ctt
//
LOCUS       DAYYYC010000029        24275 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.029, whole genome shotgun sequence.
ACCESSION   DAYYYC010000029 DAYYYC010000000
VERSION     DAYYYC010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.029"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(315..1004)
                     /gene="rplA"
                     /locus_tag="ACHBV5_001280"
     CDS             complement(315..1004)
                     /gene="rplA"
                     /locus_tag="ACHBV5_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFM9967071.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1212..1637)
                     /gene="rplK"
                     /locus_tag="ACHBV5_001281"
     CDS             complement(1212..1637)
                     /gene="rplK"
                     /locus_tag="ACHBV5_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFM9967072.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            1769..1906
                     /locus_tag="ACHBV5_001282"
     CDS             1769..1906
                     /locus_tag="ACHBV5_001282"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967073.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEVADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            complement(1946..2662)
                     /gene="ldcB"
                     /locus_tag="ACHBV5_001283"
     CDS             complement(1946..2662)
                     /gene="ldcB"
                     /locus_tag="ACHBV5_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HFM9967074.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKTKNEDGETKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2665..3135)
                     /locus_tag="ACHBV5_001284"
     CDS             complement(2665..3135)
                     /locus_tag="ACHBV5_001284"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFM9967075.1"
                     /translation="MCLICQRIDLIKKEENPYFVKELETGYLVVGDHQYFEGYSLFLA
                     KEHVSELHHLKKETRLRFLEEMSLVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQAKPDEIKRLVKRLSSEVDKLLEIKE"
     gene            complement(3137..4174)
                     /locus_tag="ACHBV5_001285"
     CDS             complement(3137..4174)
                     /locus_tag="ACHBV5_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFM9967076.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREIADYLVKTLEGFGYQPVRTSK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKMDRIGGFPWNMIEGENCTI
                     HVASTGEKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTSEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRIYKEEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSTLVD"
     gene            complement(4378..5703)
                     /gene="brnQ"
                     /locus_tag="ACHBV5_001286"
     CDS             complement(4378..5703)
                     /gene="brnQ"
                     /locus_tag="ACHBV5_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFM9967077.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5874..6161)
                     /locus_tag="ACHBV5_001287"
                     /pseudo
     CDS             complement(5874..6161)
                     /locus_tag="ACHBV5_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(6321..6899)
                     /locus_tag="ACHBV5_001288"
     CDS             complement(6321..6899)
                     /locus_tag="ACHBV5_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HFM9967078.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6953..8353)
                     /gene="pepV"
                     /locus_tag="ACHBV5_001289"
     CDS             complement(6953..8353)
                     /gene="pepV"
                     /locus_tag="ACHBV5_001289"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFM9967079.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8366..8971)
                     /locus_tag="ACHBV5_001290"
     CDS             complement(8366..8971)
                     /locus_tag="ACHBV5_001290"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFM9967080.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVCEKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            9142..9942
                     /locus_tag="ACHBV5_001291"
     CDS             9142..9942
                     /locus_tag="ACHBV5_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM9967081.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKESSSQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTYLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSTDSPSN
                     YIVFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10120..10953)
                     /locus_tag="ACHBV5_001292"
     CDS             complement(10120..10953)
                     /locus_tag="ACHBV5_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HFM9967082.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLQGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSKGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQRHNLKLLASLIEKHRYVEDVKNFFDF
                     L"
     gene            complement(10943..12787)
                     /gene="uvrC"
                     /locus_tag="ACHBV5_001293"
     CDS             complement(10943..12787)
                     /gene="uvrC"
                     /locus_tag="ACHBV5_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFM9967083.1"
                     /translation="MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(12826..13527)
                     /locus_tag="ACHBV5_001294"
     CDS             complement(12826..13527)
                     /locus_tag="ACHBV5_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HFM9967084.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(13606..14838)
                     /gene="murN"
                     /locus_tag="ACHBV5_001295"
     CDS             complement(13606..14838)
                     /gene="murN"
                     /locus_tag="ACHBV5_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HFM9967085.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14843..16063)
                     /gene="murM"
                     /locus_tag="ACHBV5_001296"
     CDS             complement(14843..16063)
                     /gene="murM"
                     /locus_tag="ACHBV5_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HFM9967086.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16175..16954)
                     /locus_tag="ACHBV5_001297"
     CDS             complement(16175..16954)
                     /locus_tag="ACHBV5_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFM9967087.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17023..18684)
                     /locus_tag="ACHBV5_001298"
     CDS             complement(17023..18684)
                     /locus_tag="ACHBV5_001298"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFM9967088.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18859..21081)
                     /gene="recJ"
                     /locus_tag="ACHBV5_001299"
     CDS             complement(18859..21081)
                     /gene="recJ"
                     /locus_tag="ACHBV5_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFM9967089.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21358..22116
                     /locus_tag="ACHBV5_001300"
     CDS             21358..22116
                     /locus_tag="ACHBV5_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFM9967090.1"
                     /translation="MVLVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDRMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            22156..22920
                     /locus_tag="ACHBV5_001301"
     CDS             22156..22920
                     /locus_tag="ACHBV5_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFM9967091.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22933..23610
                     /locus_tag="ACHBV5_001302"
     CDS             22933..23610
                     /locus_tag="ACHBV5_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFM9967092.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGATLLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23620..>24275
                     /locus_tag="ACHBV5_001303"
     CDS             23620..>24275
                     /locus_tag="ACHBV5_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFM9967093.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     "
BASE COUNT         6846 a         5635 c         4530 g         7264 t
ORIGIN      
        1 ttgatagtgg tcgccccagc cagatacctt atccgctata taggccttat tatcacgttc
       61 ctgttcgtag agccacgatt tcgctatccc ttcctctgac gattcttatt tccagcgtca
      121 gacttaaaac ggtctatccc cagaccgttt taatccgcta cctcacgata gtcagacttg
      181 ggaatcgcta ttgggttcac cggtagtagg tgcccaccga ggacttacac ctcagatata
      241 cgacatgccc gtcgtacatc aaaaaaagtt gagacatagt gtcttcaact tttttacatt
      301 actttaacta ctgattaaag tgagtttacg tcaactttga taccaacacc ttgagtagtt
      361 gtgatagtca agtttgttac gtaagttcct ttagctgtag ctggttttgc tttttggatt
      421 gtttcgttga aagctttaaa gttttcaacc aatttttcag cttcaaatga tactttaccg
      481 atgattgctt gaacgttacc tgcacggtca gcacggtaag tgattttacc acctttagac
      541 tcttcaactg ctttagcaac atccattgtt acagtaccag ttttagggtt tggcatcaag
      601 ttacgtggtc caaggacacg tccaagacgt ccaacaagag ccatcatatc aggtgtagcg
      661 ataactacgt cgaagtccaa ccaaccgtcg ttgattttag caacaaggtc atcttcacca
      721 acaaagtctg caccagcagc ttttgcttct tcagcttttg caccacgtgc gaaaacaaga
      781 acacgtgaag ttttaccagt accgtttggc aataccattg ctccacggat ttgttggtca
      841 gcttttttaa cgtcgatgtt caagttgtaa gcaacttcta cagttgcatc aaattttgca
      901 aagttagttt cttttgcaag tgctacagct tcttctacac tgtatgcttt tgtgctgtcg
      961 attttctcaa gagcagcacg aagttgtttg ctttttttag ccattttcta ttctccttgt
     1021 aagtggttca atcgattttc atctcccacg tcacttctcg aaatgatgaa gtcttgcggg
     1081 ttttcagtct actatttttc tcttcctacg gccttaagct cccttgctgt acccaagtac
     1141 aagcctcagt cacttgccta gtatgaaaag caactaatag actgctgtga gattttctac
     1201 tgtgttattg attagtcaac aacagtgaat cccatagaac gagcagtacc ttcgatcata
     1261 cgcattgcag actctacgtt tgctgcgttc aaatctggca tcttagtttc tgcaatttct
     1321 tgtacttgtg cacgagtaac tgtagcaact ttagttttat taggtgtacc tgatcctttt
     1381 tcaacacctg cagctttttt caaaagaaca gcagctggtg gtgttttcgt aacgaaagta
     1441 aatgatttat cttcgtaaac tgagataaca actggaatga tcataccagc ttggtcagct
     1501 gtacgagcgt tgaactcttt tgtgaatccc atgatgttga taccagcttg accaagagca
     1561 ggtccaaccg gtggagctgg tgtagcttta ccagcaggga tttgcaattt tacaagtttt
     1621 tcgacttttt tagccatttt taaatcctcc tttgtggttt tggcggtaat tagagatttt
     1681 tacctcccac aagtatgttt ttcacatacc catccattat acactattta tctggaattg
     1741 caagagaaaa gtttattttt tgtactcaat gaaaatcaaa gagcaaacta ggaagctagc
     1801 cgcaggctgc tcaaagtaca gctttgaggt tgcagataaa actgacgaag tcagctcaaa
     1861 acactgtttt gaggttgtga atagaaccga cgcagtcagt aggtaaggcg acgctgacgt
     1921 ggtttgaaga gattttcgaa gagtattaat cgacgtagtc tccgccttca aagccatagt
     1981 attcttccaa actgagacca cttgcagcaa tttctttagc ttcttttcct acataacgca
     2041 ggtgccattc ttcagccata tagcctgttt ccttttcctt gcctttgaga taacggacaa
     2101 caaagccata atcagctgca tgatccaaga gccattgggc tgctttttct tctgtcacca
     2161 aatcaccatc agtcccaatc acatcaaagg ccaagcctgt ctggtgttcg ctatagccag
     2221 gacgggcaga gtaacggtca gctgctgcct ttccatcttg gttgacataa tcttgataga
     2281 gcttggtctg agtttcataa cttctaaaac cactgtaatg atcactaata gggaaacctg
     2341 cctcttgcat cgctttgatg agtttgacca actctgcctt ggctgttgga ttttcccctg
     2401 gattatagtc tttagacaat ggatagtgtt tgttggctac gatgatttca tcgtatttcc
     2461 cttgaatgct gtagtaatca cctttattga ccacttctgc tttcttctgg gcagctcctt
     2521 gagacttact accgactgtt ccatcagctt tggctgtctg ttctgtctta gtttctccat
     2581 cttcattttt tgttttttct tgtgaacaag ctgctagact caaggctagc aaagctgtca
     2641 agactaggta tcttttcttc atttctactc ctttatttct aatagtttat ctacttctga
     2701 cgataaacgt ttgactaatc ttttaatctc atccggtttt gcttggcagg tttctgctgt
     2761 catttcttca aagggaaccc accagactgg tccacgaccc ttgagaccat gaccattcat
     2821 atcacctgtc cgtcgtggaa acagatgcca atgaagatga gcatcgccat ttcctagcag
     2881 ttcgatattc attttctcag cagcaaaggc cttggcaact gcctcttgga ctaaactcat
     2941 ttcttctaga aaacggagtc ttgtctcctt tttcaaatgg tgcaattcgc tgacatgctc
     3001 cttggctaga aagagactat agccttcaaa atactggtgg tctccaacca caagatagcc
     3061 tgtttccaac tctttgacaa agtaaggatt ttcttccttc ttgatgaggt caattctctg
     3121 acaaataagg cacatattag tccaccaacg tgctcttaag ataagcatcg accattcgtt
     3181 ctgttgcgat caccgagtca atatgggtac gctcatagga atggctagac tctataccag
     3241 caccgagaag ggcgtgtttg acttctgccc ctgcagacat agccgctgaa gcgtccgaac
     3301 cataaaatgg atagatatcc agcttaaatg gaatatcttg ctctttcgcc aaagccacca
     3361 aatgttgacg gaagtcatag tgataaggtc cagaagcatc cttgacacag atagacactg
     3421 tatattcgtc tgtttgctgg tcatctccca tggctcccat atccacagcc agatattcta
     3481 ctacctgagc aggaatgtta gagtttgcac cgtgtcccac ttcttcaaag actgaaaaag
     3541 caaaatgagt tgttacgggc aattcaatct tctcttcctt ataaatgcga aggagattga
     3601 gcaaaatcgc cgcactgacc ttgtcatcca aatggcgaga cttgataaaa cctgtctctg
     3661 tcacgacagt tcgtgggtca aaactgataa aatcaccgac ctcaatgcca agagcacgag
     3721 tttctttttc actagttact ttggcgtcca aacgcacttc catattgtct tgcgtgcgtt
     3781 ctgcagttcc tgcatcctta tagacatggc aagaagtttg gtggatgagg atggttcctg
     3841 atactttttc acctgtgcta gccacatgaa tggtacagtt ttctccttca atcatgttcc
     3901 aaggaaagcc accgatacgg tccattttga gacggccgtc tggtttgaca gcacggacaa
     3961 tagcaccaag cgtatctaca tgggcagtca catagcgatg ttgctcatca ttttgacctt
     4021 taatagttac attgacaccg cccttggatg tgcgaaccgg ctggtaacca aaaccttcta
     4081 gagtcttaac taaatagtcc gcaatctcac gagtaaagcc tgttggcgac gcaatggctg
     4141 tcagttcttt gatatattct actgtttgat tcatttcttc acctcttttg ctacctatta
     4201 taacacattt atcatcggat aaaaaaagaa aatcactcct gtagacttga ctacaaaagt
     4261 gattttatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgtacttg
     4321 agtacgacaa ggcgacgttg acgcggtttg aatttgattt tcgaagagta ttagtgatta
     4381 ttccatttca aaaacatcgc tttcttgctt gtttggtaga accaatgaga gcaagattcc
     4441 aacaatggct ggcaccaacc atgggagaga tgccttggca aaaggaagaa cgctaacaag
     4501 atttgcaaga aactcaacct taaacgagct tcctagtacg cttgcaatgg caataactgt
     4561 aaccacagca attgtcaact gcatacctgg ttttgaaaga gcaacaaatt tgttgacaat
     4621 gacaatcata acgatagcaa tcgtgattgg gtacaagata accagtactg gaattgagta
     4681 cttgataatc gcatcaagac ccaaattggc aatagcaaat ccaatcaagg taaaggctgt
     4741 cgcataaacc ttgtagctga tttgtgggaa gcgctcatta aagaactcag ctgttgacac
     4801 aatcaaacca acagtcgttg tgaagcaggt tacggtaacc atagctgcaa ggaagagttg
     4861 agctgttgag ccaaagattt cttgagtggc ttgtgacaag atgtaaacac ctggtgttcc
     4921 acccttcatc gcttcagctg gtactgggaa atgatttcca agaaaaccta aaccgatgta
     4981 aagagcgctg aaggcaaggg caacaacgat accaacaacc caaatagttg aaatgtattc
     5041 tttcttactt gaaaatccaa gttgtttcaa ggtttgaact gcgattacgc taaaggccac
     5101 tgaggcaagg gcgtccaagg tattgtaacc ttctaggaaa cctgtaccaa aggcagaagc
     5161 ttgataagca gctgaagcag cttgaggact tgttccacca tatttgatag ctcccagaac
     5221 gaccaagata acaatcaaaa ttgcaaagac tggcgttaaa atacgtccaa tgcggtctaa
     5281 gatttttgat ggattaagcg aaatcaaata ggctgccgca aaatacagaa ccgtaaatac
     5341 aatcaagcca agtcctttat ttgcatccga caaaaggggg ctaatcccta cttcgtaagc
     5401 tgttgtagca gtacgtgggg tagcaaagaa tggaccgatt gacaagtaaa gaactgagag
     5461 gtaaagagtc gcaaaccaag gcgctatctt cgttgaaatc tcgtagatat accctttagg
     5521 atttagcgtt ccaataataa gggtcaagac ggcgatacca acgcctgaaa agacaaaacc
     5581 tgcgatggca ggaagaaaat gttctccaga tagagcacct agagaaggcg gaaaaatcaa
     5641 gttccccgca ccaaaaaata ttccaaacag gagcaaacct gttagggtac cttttttagc
     5701 cataaaaatc tccttcatat ttataaaata ctgacctagt ataccacgat taggagtctg
     5761 aaaaaagcat cacgaggcaa atattaaatg ttttcaattt tcttaaaaat aagaattatc
     5821 taaaaataaa actctcctac ccagtccaca ccaagtagga gaaatgcaaa attttaaagt
     5881 tcttcaaagg ctaacatgcc accctggaca ttgataacat tataaccttg ttctaacagg
     5941 aattggcaag cacgcgccga tctcattcca gatttgcaaa taatataatg caagcgatct
     6001 ttgtccaatt aatcataact atcagtcaat tgactaagcg gtaggttgtg ggcaccttct
     6061 aaatgaagag ctgcaaactc atccacttct ctcacatcca ctagagaaag ctggtcgttt
     6121 tggtaaagct ggtaaaatgc gtcaaaggct atttctttca ttctttttct tctaatactc
     6181 ttcgaaaatc tcttcaaacc acgtcagcgt cgccttaccg tgcgtatgtt accgacttcg
     6241 tcagttttat ctgcaacctc aaagctgtac tttgagcagc ctacgactag cttcctagtt
     6301 tgctctttga ttttcattga ctataaaatg gttttaattc tttttttcaa atctggcact
     6361 acttctgcct caaaccaagg atttttggcc atccagattt gatttcgtgg tgatgggtga
     6421 actagcggaa aataggctgg cagatagtct ttatagtgtt tcaccctctc cgttaccttc
     6481 ccactgattt tctcctgtaa atagtaggct tgggcatatt gcccaatcaa gagggttaac
     6541 tgaatatcag gcaattcctg taagagctgc ggatgccatt tttctgcaaa acctgtacga
     6601 ggcggaagat cacccgactt gccatgtcct ggaaagtaga aatccatagg caaaacagca
     6661 aaataacctg aattgtaaaa ggtatcttca tccacaccta gccagtcccg caagcggtca
     6721 ccacttttat ctttccagta aaggcctgct tcttgagttt taagtcccgg agcctgaccg
     6781 atgatattga tgcgagcagt ttttggcgct gcaaagagag gctcaatgcc acgctctgta
     6841 tagctggcat tctgtgaatc cgccatgata gcctgtttga ttctttcgat ttgagacatc
     6901 tactttccct ccaaaaagaa gtccaagcat aagatctcag acttctatcg ttttatttga
     6961 tcaattcgta aatagcttcg gcataaattg ctgctgctcg gaaaagatca tccaaggcga
     7021 taaattcatt ggcttggtgc atggtatcaa tcgagtctgg gaacatagca ccgtaggcaa
     7081 ctccgcgttc tagcaagcga ccaaaggttc caccaccgat gacttgttca tgacctttaa
     7141 ggccagtttg tttttcatag atattcaaca aggtttgcac aagtggatct tccattggca
     7201 catagtgagg cgtgtgaccg tgttcagaca ggctaacaga aacaactggc aagttttcaa
     7261 ggattgactt gatttgttct ggacttgttc cttttggata gcggatgttg agggcaatgg
     7321 tattatcagc acttgtttca tcgaagcgga agacgccggc attcatagaa agagcaccca
     7381 tcttttcatc cacatgagca atcttaagat tttcaccctc atgatcgttc aagagaattt
     7441 tacctgcgat gtcaaggtag tctttggctg gaccagcaaa gccaaactgg ctgaggaaga
     7501 gggcaaggta agttgcgcca ttgacacctg aagcaggcat agcaccgtgg gctgatttac
     7561 caatgatcgt caccttgtat ttgccagctt cttcttggag ttctcctcta agtttgtgtt
     7621 ctgcaacaaa ggcatctagt ttagcttgca agtcagccaa gtcacctgaa acgactgctg
     7681 ttgctgattc tggtaccata ttttcacgta aaccacctgt aaagctgtga agacgggcaa
     7741 cacctgtatt ttctcctgca aagtggaggt attccgtgat atttcctttt tcaccattga
     7801 tgattggaaa ttcagcatct ggtgagaaac cgaaatctgg tttggcaagt cctacgtgct
     7861 caaagtagta gtccatgtct gcccagcctg attcttcgtc tgttccaacg atgaagcgaa
     7921 ctttcttaga agttggaaga cccaattctt tgatgatttt caaaccatag taacaagctg
     7981 ttgtaggacc cttatcgtcc gaagccccgc gcgcataaag gcgaccatct ttgatagttg
     8041 gtgtgtaagg gtctgtgtcc caaccgctac cagcaggcac cacatccata tgggcaaaga
     8101 ttccgagaac ttcttctcca tcaccaaact caaaatgtcc tgcatagtta tcaacattct
     8161 tagttgggta gccatcgcgg tctgcgattt caaggaattt ctccaaggct tttactggac
     8221 caggcccaaa tggatgctgg gcatcagcct tgctgtcatc acgttctgaa ttgatttcca
     8281 aaaggctaaa caagtcagcc aagaggtctt ctttgcgttt ttctacttct gctgtaaaat
     8341 caattgctgt cattttttct tctttctatc ttttctcgat gatttcatct actggcaagc
     8401 ggtagcttgg ttccaatttt tcgtctgtat aacccactgt gatcaagagt tctgggcgga
     8461 aacggtcttc gatttccaaa acttcattaa cttttgattt gtcaaaacca aggataatat
     8521 tggaaccaat tccttggtct gtaagagcga gaaccaagtt catagcaacc aaacctgcat
     8581 tgagtgctag gtagtcgctg acttgttgtt cattgtagcg tgcaaattca gctggcaaat
     8641 ttttcatgaa gtattgaagt tgttcttctg agaaattgtt agcaccacca actcgggcaa
     8701 tcttacgagc gcgtttggca aggtctgtat ctgtaaatag ggcaatggtt acaggtgctg
     8761 atgatacctg ttcaaaattg gaaccataag ctaactttgc cagttcagca tttttctcac
     8821 ataccaccac aaatttccaa ggctggctgt tgtgggcgct tggcgccaag gttgcaattt
     8881 cgatagccgt acgcacatct tttggatcaa caggcttatc agtgaaatgc ttggtcgcat
     8941 gacgtttttt atttaattca agaaatttca taatcgattt ccttttctaa ttctactgct
     9001 tccattctac cataatttga aagagcttgc agggattttt catgattaag tttttctatc
     9061 acagacataa aagatatata ttggtttatc aggaaagttt ctgataaact agcaagtact
     9121 ttacatttga atggagacag tatgaaaaaa tttagcctat tactagctat cctaccattt
     9181 ttggttgcct gtgggaatca agctacaccc aaagagtcca gctctcaaaa gacaatcgtc
     9241 cttgctacag ctggcgatgt gccaccattt gactacgaag acaagggcaa tctgacaggc
     9301 ttcgatatcg aagtcctaaa agcagtggat gaaaaactca gcgattacga gattcaattc
     9361 caaagaactg cttgggagag catcttccca ggacttgatt ctggtcacta tcaagcagca
     9421 gctaataatt tgagttacac aaaagagcgc gctgaaaaat acctctactc gcttccaatt
     9481 tccaacaatc ccctcgtcct tgtcagcaac aagaaaaatc ctttgactta tcttgaccag
     9541 atcgctggta aaacaacaca agaggatacc ggaacttcta acgctcaatt catcaataac
     9601 tggaatcaga aacacactga taatcccgct acaattgatt tttctggtga ggatattggt
     9661 aaacgaatcc tagaccttgc taacggagag tttgatttcc tagtttttga caaggtatcc
     9721 gttcaaaaga ttatcaagga ccgtggttta gacctctcag tcgttgattt accttctaca
     9781 gatagcccca gcaactatat cgttttctca agtgaccaaa aagagtttaa agagaaattt
     9841 gataaagcgc tcaaagaact ctatcaagac ggaacccttg aaaaactcag caatacctat
     9901 ctaggtggtt cttacctccc agatcaatct cagttacaat aacactcttc gaaaatctct
     9961 tcaaaccacg tcagctttat ctgcaacctc aaagctgtgc tttgagcaac ctacggctag
    10021 cttcctagtt tgctctttga ttttcattga gtataagata tataaaagcg attggactac
    10081 caatcgtttt tagtttgcat tggttatttt aggaaactct tacaaaaaat caaaaaaatt
    10141 cttcacatcc tctacatacc tatgcttttc tattaagctt gctaatagtt tcagattgtg
    10201 cctctgatag ttatcttcac gacgtagttc ttcatacatt tcgataaagg gaagcccctt
    10261 ggatttggcc aattctaact cagcctcgta atcataagca actttacgaa attggatatt
    10321 gagtaattcc ccatcttcaa cctctatcac ggcatactgg gcacggtgat tttttaacgc
    10381 ctcccaatta aaatagggca tgccaatcga ccctggattg atgatttgtt gccctttact
    10441 gccgtagcga agcaactgct tgtgaacatg accataaact gccacgtccg tttccgcatc
    10501 tagcagttgg tcaaatttct ctgtatcatt ctcaactagc aagtcaccac catagttttt
    10561 gtcaggtaaa ttatgagaga tagaaaagcg caatccgtca atttctttct tttccagcaa
    10621 aggcaagctt cgtagccaga caatcgttgc aggatccatt cgctccatca aaaactgggt
    10681 catgcgcatt gactggattt ctttcggata ttccaaacca tattcgccat ccaagacctc
    10741 aaggacacga tcatcccaat tgcctcgaac acttgctgtg ataggaaggt cctttagcag
    10801 ggcgactaag tcatttgcgc ctggaccagg aagaaaaata tctccctgaa gccaatattc
    10861 actggcccct tgatttttag catctgcaat cactgcttct agcgccgtcg cattgccatg
    10921 aacatctgat aaaattgcga ttttatggtt cattgtggtt tccttccgtt tggtaatcta
    10981 ctctttcttc tgctacttga ggcaaggctt ctccctgcgg gttcaacttt ctttgcacag
    11041 cctctgcaac gactctaggt accccaactt cgacaatctc atccacactg gcttccttga
    11101 ttttggtcaa agacttgaaa tgcttcataa gattctgctt gcgtttaggt cccagaccgt
    11161 caatcccatc caattgagat gagaaagaat ttttggagcg cagttggcgg tggaaagtga
    11221 tagcaaagcg gtgcacctca tcttggatgc gttggaggag gaaaaattcc tgagaattgc
    11281 gagacaagtc caccacctca agcggatctc caaagagcaa ttcatgggtt tggtgcttat
    11341 cattcttttg cagcccagca attggaatat ccaagcccag ttcctcttgg atgacttgct
    11401 tagcaatatt gacttgacct tgccccccat caatcacaat caaatctgga ggagtcaaag
    11461 cctcacgctg tactcgacca tagcgtctgc gaatgacttc tctcatacta gcatagtcgt
    11521 ccggcccaac aacggttttt atcttgtact tacggtaatc ttttttactt ggcctgccgt
    11581 taacaaagac caccatggct gaaacaggac tggtccccat gatgttggag ttatcgaagg
    11641 actcgatgcg aactggagtc ggaatttgga gcaaacgtcc tagattttca atagctcctt
    11701 gggtcttttc gactgatttt tctagcagat tgaacttctg ctctagacta acacgagcat
    11761 tttttatggc tagattgacc agctgttttt tctctccacg ttggggtttg agaatcttgg
    11821 tatccaccaa agccttgaca gcttcttcgt caatatcctg cggaatcagt acctcattgg
    11881 gaactaggtg agatttttct tgatagaatt gtcccacata ggtcaagaaa tcctcatctg
    11941 gatcattgaa gtaggggaag agattgacat cgcgctcgat gagcttgccc tgacgaacaa
    12001 agaaaacctg cacacacatc cagcccttat ccacatagta gccaaagaca tcgcgatttt
    12061 ggagatcctt agccatgacc cgttgcttgg ttcgaagtgt tccaatggcc tgaatcaggt
    12121 cacggtattc cgctgcccgt tcaaactcca tactttgtgc tgttactgcc attttactct
    12181 tgagatcatc gatgattttg tcatcctgac ctttcagaaa atcagacacc tcctgggcca
    12241 tggacttgaa ataggcctcg tcattcttac agatggtgtg ggccatacat tggccgatat
    12301 ggtagtaaaa acagacctta gagggcgggt tggtacattt tcgaaaaggg aaaatcctat
    12361 ctagaagtcg cttgatttca ttggctgccc ccacatctgg ataagggcca aaataaagac
    12421 caccgtcctt tttgacctga cgagtaatga taagccgtgg atagtgctca ttggtgattt
    12481 tgataaaagg ataagacttg tcatccttga gcatgatatt gtacttgggc ttattttcct
    12541 tgatcaggtt gatttccagc agaagcgcct caatattaga ctccgtaaca ataaattcaa
    12601 aatccacaat ttcagacacc aaggcctctg ttttggtatc atgacttcca cggaaataag
    12661 acctcacgcg attacgcaga tttttagcct ttcctacata gataatggtg ccgtttttat
    12721 ccttgtaaat gtagcaacca gggctggtcg gcaagagctc tagttttggt ttaatcaagt
    12781 tgttcatagt tccattatag caaaaaagta gggaaagata gtaccctact cattagtctc
    12841 atatattttt cggaggtttg caacatcctc ttcctggata ccataaaagg aacctgctgg
    12901 ttgcatgaca gacttctcat ctgtatggtc caagccaatc gcatgaccta actcatgttc
    12961 tgccgtatgg acaaggcgtt cataggaata gccatagtat ggattggaca aataataatg
    13021 attcaaccgc accgttacgg acaagaattg ccctgttaag agattagttt gactttccgc
    13081 ctctcctgcc acaggagtgc ctccgtcgtt catctccgta gccgtaatat ccgccttact
    13141 agactcagtc acgagttcaa agttaaaagc accagtttga ttccagttct ggattgcttc
    13201 taaataagcc tcttgaaagc gtgaatccat ctgcggatcc aggtaaatac gagcagaggc
    13261 ctgtggccac cttccttcag aatgctggtg actatctgtc tggcttaact taggcagttg
    13321 ccctgttttc tcccattggt caatactttg ttgaccaatt tttactgacc gttctgcttg
    13381 ctttagcgct ccttgaaaat ccccgttcag ataccagaga agtccgaaag caagcacaca
    13441 taagagcaca actatccaaa ccagacgcca aaacaaacgc cacacaaaag aaaagaaagc
    13501 ccctatcaaa cgaaaaagcc agcgcatgtc tctccacctt tctagcaaat aaaaattatt
    13561 ttactaaaag aagctaaaag aaatctaaat actgactttt tcatcttaac gtcctactat
    13621 ttttttgagt aactggatag ctttgtattt taaaggagat ggatggtaac ggaaagtacc
    13681 tgctttgcgt acaatatagc cattaaaatt ctgtttaaaa cgcaaaacac catcacttcc
    13741 atcaaaaatc ccttgaatgc ctaggaagtt gtatttaggt attccacgtt ttatgctttc
    13801 caacataaca tatttttgaa gcagtgcagg ggcatagaac ttattaaact cagtgtagga
    13861 accactaaag agataagtcg tttcctgagg catataaaca aataaactcc cagctaaaac
    13921 aatatcttct tctccatatt tttcaatcaa gtctcgcgct tctgcttttc gaacttcaaa
    13981 cgtttcaaat tgactagaat attctctcag ttgattttgt tttttctcag aatgaggatt
    14041 tttactcaaa tcaagtcgca acttgtccaa gttttcttct agtttatttt gttcaccttg
    14101 caatttgctc atatagtccg aaaaatttaa gcttgctatg agaaactccg cttgttctcc
    14161 aaaagtatca taaaaatgct cataatattc taaactttta tcactatatt ctctacgttc
    14221 agaggtttct tttgttatat tcttaaaaat cgatagttct tcacgtttta actttttcaa
    14281 tcgaatgcca aaggtttcag cctttttcac caagggttta ccctttttgc taaaactttt
    14341 aagcaaactc ttttcagtta attcagttaa atctttatag tataaccaat ctggttctcc
    14401 acctgggtaa cctgttgtta agccatcaaa ttgataacct aaatcagtca aaccttgaat
    14461 aatacttttt ttctcagcat ctattggatt accttggcta tcaaaagttt gataagtttc
    14521 ataaggtttt acaagcaact ctaatacacc attttgcttg gcatattctt ttaactctgc
    14581 ataaaaaact ggaagagcat cttgttgggt ataaatcggc cccgaattga gttccatatg
    14641 cagaccaccc agcatgggca agctataaac cagagctgca acttgaattt ctccttcttg
    14701 tttcaaagca agataaacaa ttcgagcccc tcttttttct agcaaatccc ccatctggac
    14761 agattgcata aaggaacgag aagaaacctg atcagaataa gtctgaaact cttctttcgt
    14821 gagtgttgtt agtgccatat acttactttc tatgtttttt tcttaatgtt ttacggaaat
    14881 caagagcaag tcttaacaga ggatagagag gatgagtggg cattgtaaat tcacccaagt
    14941 attcttcaat cgttggatta aatttttcct taaaatgata aagtccacca ttgagagagt
    15001 tttcaacacc acctaaattt tgccagacca tacctcgctc aaaggcatag cgagccgttt
    15061 cataccatgt taaaattggt gcattgtaac gtttaaaatc atcatccata ccagcatata
    15121 tattgacaga ggtagtacca aattccaaac tcaaagtagc cgctaaagga actctcgctt
    15181 gacctacatc tatatattcc tgcaagaagg tcaattcctc taacaaacgt tctttttcct
    15241 tcttctgcgc ttctactttt gaagttcgag tcgactcagt aaaggtctct tccaaggctc
    15301 tatttttcgc taactgttct tctaattctt gcgaacgttt agaaacatcc aaggtggcca
    15361 aggtgatata ggccttgtcc ttaaaattat ctaacaattt tttataatag gcttcattcc
    15421 tcaaatgaat ctcttttcgc ttctcagttt ttttcatcaa ctccgaaaat gaatctaata
    15481 gttccagtcc accatattga atctcaagcc ctttgtttcg tgctgttcga atagcctgtt
    15541 ttgttgactt ggaaagttta tcttcttcaa aattttcctt gtatattttc gcctgaatac
    15601 gaggttgaat ggtgtctccc atttcctccg tttttcctga ccaccttact cccatttgtt
    15661 gcaaactatc aataatagcc agattttcag gaaattctgt cttttcctga ttgattaaac
    15721 tttgagatag gcaaatactt gggtcaaaag tcacaaaaac cgctctctta ctgcgagcat
    15781 aggacttaat agactgaatg gcaaaattca agagttcttt atccccataa tccaatatag
    15841 gtcctcttgg gatgtaaaac attttatagc ctagcggaag agttctaatc aaaatactag
    15901 ctgtcgccag taatttttct tccctgtaaa caccaaactt ctcatgttgc caattagact
    15961 taacttcctc ccaagcacta ctttgtaata cattggctaa ttcatgttct ttgacaaact
    16021 gatcatattc taatgtggga atgccaattt gataacggta catttcctac tctctttcct
    16081 ccagtatttt attactattc tactactttc gtttgaaaag tctagtgaaa acatatttta
    16141 ttttagttct actcccccta tgctgaagtt caaactaagt cagtctctct tctaatttga
    16201 aatcaattgg tagggttgtt aaaaaaactt ccaattgttt ttcccagtag taccactcgt
    16261 gagttccagc actatggcta taggtcacat caaaacctag ttttttgaga tttttcactg
    16321 cgagattatt ggcttcgtac aagaaatcct gttcgccaca ccacgcccaa agtttggtct
    16381 ttttatccga ttttttagcc agactttcaa gagaataggg actagttgtc cagtctctaa
    16441 tctctccaaa aacacctctc cagtaggctg gacttcccag attttgactt tcaggagaaa
    16501 agttttgaaa gctgagggca cctgaaaaac tagctgcatg agaaaaacga tttgtcgtaa
    16561 gagccagttt gaagcagccg tagcctccca tagaaagacc agcgataaag gtcttttcac
    16621 gcttgctagt catattaggg aagaagcgtt tcagaacctg tggcaattcc tctgctagag
    16681 ccgtgtagta gtcaaaacca tactgggtat cggtgtacca accattgctg gtattgggca
    16741 taacaacgat gagattagtt cctcgaagca agcgttctac attggtccgc ttaagccaac
    16801 tattatgatt tccagacatc ccgtgcaaaa ggtacaagac gggaatatct tcacactctg
    16861 gttcttccac tcgattggca tcagggtaga ggacattcac cccccactcc atatccaata
    16921 cttgtgagta atactcgatt ttcattactg ccatgatttt ctccttctat ttttctataa
    16981 gaaaaagccg aaactcgact ttctctctgt ttatttcaac gattattttg cttccatgac
    17041 tactggtaaa atagctggac gacgcttggt ttggtcaaag agatacttgg tcaaattatc
    17101 tcgaaccttc cctttaagat ctgcccagtc aaagtcatct ccttgaagat aatcttctac
    17161 cgtttggtta atcaattctg aactttcacg gagaatatcg cgactcttct tgagataaac
    17221 aaatccacgc gtgtgaacac gagccctagc cacaattttc ttctcacgac ggttgactgt
    17281 aatagccacg atgaaaattc catcctctga caagacctta cggtcacgaa gaacaacatt
    17341 tccaacatca ccaatggcat tcccatcaat caagatatct cctgctgaaa ccgatccagc
    17401 tggaacaaag tctccattct cgtaagccat ggtcgtcccc tttttaggaa tgaaaatgcg
    17461 ttctggcaac atcccaactg ccatggcagc cttagcgtga gcatccaact cacgatactc
    17521 cccttggaca gggaagaggt acttaggttg caaaagattg atcatcagct gcaaatcacg
    17581 cacatttccg tgccctgata catgtaaact ttgggtaatc aatttgacaa ccccacctgc
    17641 ctgataaatc atattttcca cacgcgcaac aaaggcttct ttagcaatag acggagccgt
    17701 agcaatatag accaggtccc catccttgat ttctacataa cgatggcgac caatcgacat
    17761 cttacgaagt ccattgatag gttcacccat acgacctgtc tcaagaataa tcaactcatg
    17821 gtcttcaaag cgagacatat ctttaggctt aatcaagaga atttcgttgg ctaaagacaa
    17881 cttcttaaga cgaatcgctg tgcggacgat attttcaata tcaaatcctg tcaagacgat
    17941 acgtcgacct gttttatccg cagcgtcaaa aatctgctga atacgagaaa gattactgga
    18001 aacagctgca acgatgatac gaccttccca gtcagcaata gtttgggtaa tttcatccct
    18061 aacttcactt tcactagcca cctgaatatt gctgtctgca ttggccgaat cactgaggag
    18121 agccaggacg ccgtcacgac caatctctgc caaacgagca aaatcagttg cataagattc
    18181 actagccgtt tggtcaaatt tgaagtcacc tgtataaacg atgcttcctt ccgatgtctt
    18241 caagacaatt cccagactct ctggaacgga gtaagtcgta gggaagaagg aaaccactgt
    18301 cccaccaaaa tcaatctccg tattctcatc aatgacatgg aaatcattaa atttcttaac
    18361 ggcatcattt cctttgacaa agagctttgc caactcaatg gtcaactcag acccaaatac
    18421 aggaacttta gcctctgcca agagataagg tagagcacca atggcatccg catgcccgtg
    18481 ggtcaagaaa accccagcaa tacggtcgct attttcaaaa aggtaatcca tgtttggaat
    18541 caccacatcg acccctaatt gttcattttc aggatatttt aaccctacat tcaaaacaaa
    18601 aatggactct ccaatttcag caatgtacat attttttcca ttctcacgca caccaccaag
    18661 tgttgttaaa ctgatattac tcatttttcc tccaaaatct tagtttatct tgattatagg
    18721 gcaattctac cctcttattc taaaagttct gatactttca gccgaatctt ttcctaccat
    18781 tataccattt ttttgatgat tttcaaaatg aaggtctgtt ttcaaaaaag agttgatttc
    18841 ccaactcttt cctaacttct actctttttc catcaaaaaa tcataaattt cttgcaccgt
    18901 acccagcgcc atcatttctt ggtctttaac ggtttgtttg agattttggt aaatttgact
    18961 ttctcctatc tcccgctttg gcgcctcttt attgactgtc atcacaccat cttttatcgt
    19021 cacaaagcct agttcttcaa atacttgaat catcttgacc agcaagattt gttgaatatt
    19081 aagatatgca gccaaatctt tcagcttgta gcgaatatca aactctggga actggtaaat
    19141 agtcttgtac aatttagcaa actgatctct agtcccataa cctgtcagat aataggtctt
    19201 gtcaatatca tttttgaaat agacagcaga gaaatgctgt tcctgaaaaa tggtcttcag
    19261 ctgagtaata tcctctggaa tgttttttac gacaacagct tcactagccg caagatttgg
    19321 cagttctcca ggaaaatcca agactggaac accttctggc aagactgcat tttttccacg
    19381 aatgttaaaa agttgaacac cttccactcg cgcatccacc atcatcaact ggagggcagt
    19441 ttggccattc cattggttga cagacaattt aaccgctaac tctagattct tggtttgaga
    19501 aaactctgtc gcccatctgc cttgaccaaa ggctaccact tcaaaactcg cctcaccctt
    19561 ggaaattttc agctttagat gggcattacc tgcccccata gtacgagcac tttcgacctg
    19621 aaaattcttg atataaaaaa taggtttctg attatccatt ccaaaaggag ctaaacgttc
    19681 aaaacttttg accgtttcca agctaagtgc ctccaaatcc aactcttcat ctaggtttaa
    19741 cttattcttg ccaccagcat ctgcaccttt ttcacgaaca taatcttcca aaacctgaga
    19801 taaatctgag agttgctcaa cttccagcgt catacccgct gcacctgcat gacctccaaa
    19861 ggcgatgaag aggtctcgat ggggatccag agcttcaaaa atatcgaccg cttccacact
    19921 acgagcactg cccttggcac gaccgtcttc tatattaaga acaatgactg tctgtcccaa
    19981 ttcttccaat aaacgaccag ccacgattcc tagaacccca ggattccagc cttccttggc
    20041 caagacctga accttcttct caggatccac catggtcttg gcttcttcat agatagactg
    20101 aacgatttcc ttgcgctctt cgtttttctg gtgaatcata agggcaatct catgcgcttc
    20161 ctcatcatca aatccagtca acaaatcaat ggcaggattg ggatcatcca agcgacccaa
    20221 ggcattcaaa cgaggagcaa tctggaaacc aaccgtttct tctgttactt cgttggcagc
    20281 aatcccagcc atgtccagca tttcttgcag accaatgcgc tgggtatgac ccaacatttc
    20341 cagaccatat tgaactaaga tacgattttc atccgtcaga ctcaccatat ctgcaatagt
    20401 tccaatagcg accaaatcaa gcaattccac ttgcacttct tctaacaggg cacaagccaa
    20461 cttgaaagca actccacaac cagccaaata tttaaaagga taatccgcat ctggatgttc
    20521 aggatggaca atagcataag catctggcag ggtttcaggc atggaatgat ggtctgtcac
    20581 aatgacatct actcccatag actgagccaa tgcaatagcc tcatgaccag caaccccatt
    20641 gtccaccgtc acaatcaagg aaattccttc ttgctcgata aagtatttat aaacactagc
    20701 attagggcca tagccatcgg taaaacgatt tggcaggtaa actcggcact cagcaccaag
    20761 ttgttccaaa ctttccttca caatagaagc cgaagtcatg ccatccgcat catagtctcc
    20821 ataaacgaga atattttccc cttcttcaat agcctgacga atccgctcca ctgccttgtc
    20881 catatcatgg agcagataag catcatgtaa gtcctccaag gaaggttcta aaaacttctt
    20941 cagactttct tggtcctgaa tccctctctc aaacaataac cgagccacct caggacccag
    21001 tccagccttc ttggctatct ttgtaaaatc cgcatcttct acctgcaggg caaactgcca
    21061 ttcataagta ggtgttatca aaaagacatc cactctttct aagaattcta ttgcttcatt
    21121 ataacatgat ttagacgttt tctctatcca gattgctttt ttataacatt ttatagtata
    21181 ttgaaactag aatagtacac ctctacttct aaaatattgt tagaaatcga tttgactgtc
    21241 ccgatcgatt tttcctgttc ttatttcact atagtgaatt ttttcagata tgatttgaca
    21301 agaacattct tttattgcag aatcgtgtta taaaatctaa cataaaggag ttctctcatg
    21361 gttttagtag aatttaaaaa cgtcgaaaaa tattacggag actaccacgc actccgcaac
    21421 atcaatctcc gttttgaaaa aggacaagtt gttgtcctgc ttggaccttc tggctctggg
    21481 aagtccactc ttatccgtac gatcaatggt ttagaggctg ttgacaaagg aagtctccta
    21541 gtcaatgggc accaagttgc tggtgccagc cagaaagatt tggtacctct tcgcaaggaa
    21601 gtcggcatgg tttttcaaca ttttaacctt tatccacaca aaacagtgtt agaaaacgtg
    21661 acacttgcgc ccattaaagt tctaggaatt gataaaaaag aagctgaaaa aaccgccaaa
    21721 aaatatctgg aatttgtaaa tatgtgggac aagaaagatt cctatcccgc catgctatct
    21781 ggtggacaaa aacagcggat cgccatcgct cgtggtcttg ctatgcatcc ggaactcctc
    21841 ctctttgatg aaccaacatc tgctcttgat cctgagacta tcggagatgt tctagcagtt
    21901 atgcagaaac tggcgcgtga taggatgaac atgatcatcg ttacccacga aatgggcttt
    21961 gctcgagagg ttgcggaccg cattatcttt atggccgacg gagaagtttt agtagatacg
    22021 acagatgtcg ataacttttt tgacaatcca agcgaacctc gtgcccaaca attcctcagc
    22081 aaaattatca accacgaaag tgacaaagtc aaataaggag gcgcctatga aaaaaaattc
    22141 tttttatcag cattattgat tagccttttc ggccttgctg ctgccaaacc agtccaggct
    22201 gatacaagta tcgcagacat tcaaaaaaga ggcgaactgg ttgtcggtgt caaacaagac
    22261 gttcccaatt ttggttacaa agatcccaag accggtactt attctggtat cgaaaccgac
    22321 ttggccaaga tggtagctga tgaactcaag gtcaagattc gctatgtgcc ggttacagca
    22381 caaacccgcg gcccccttct agacaatgaa caggtcgata tggatatcgc gacctttacc
    22441 atcacggacg aacgcaaaaa actctacaac tttaccagtc cctactacac agacgcttct
    22501 ggatttttgg tcaataaatc tgccaaaatc aaaaagattg aggacctaaa cggcaaaacc
    22561 atcggagtcg cccaaggttc tatcacccaa cgcctaatta ctgaactggg taaaaagaaa
    22621 ggtctgaagt ttaaattcgt cgaacttggt tcctacccag aattgattac ttccctgcac
    22681 gctcatcgta tcgatgcctt ttccgttgac cgctctattc tatctggcta cactaataaa
    22741 cggacagcac tactagatga tagtttcaag ccatctgact acggtattgt taccaagaaa
    22801 tcaaatacag agctcaacga ctatcttgat aacttggtta ctaaatggag caaggatggt
    22861 agtttgcaga aactttatga ccgttacaag ctcaaaccat ctagtcatac cgcagattaa
    22921 ggaggatacc ctatgacaga tttatcatct tggacagcct attttcagga ttttggacaa
    22981 tttttcaatg gtttcctctt tactcttgcc ctagcgattg gatcctttat cctcgccatg
    23041 gtcttaggaa tcttctttgg tgccatgtca accagtaaac gtccaatttt acgcatttta
    23101 gctcgcatct ttgtggaatt ttaccaaaat actcctctct tggtgcagtt tgttattgtt
    23161 ttttatggcc tacctcttat cagtgaccat atcatcatga ttccaattta ttggacagcc
    23221 gttctctgcg tgggactcta tcacggcgct tatatcgctg aggttattcg ttcagggatt
    23281 cagtctattc ctagtggtca gatggaggcc gccttgtcgc aaggttttac ctatatcagt
    23341 gccatgcgct tgattacctt gcctcaggcc ttccgcatca ttctccctcc attgaccaac
    23401 caaattgtta acctcatcaa gaacacctct actgtagcta tcatctctgg agtagacttg
    23461 atgtttgtga ctaagtcttg gtcggctctc aacggaaact atatcccagc ctttttaggt
    23521 gctactcttc tctactttgc cctatgcttc cctgttgccc agtttggtcg caagatggag
    23581 caagccaaca aaaaagccta ttcactttag gaggttacta tggaatctat tttagaagtt
    23641 ttaaccccag ataacctagt ctttatcttt aaaggatttg gcttgaccct ctatatttct
    23701 ctgattgcca tcatcctctc tactatcatc ggtacggtgc tagctgtcat gagaaatggc
    23761 aaaaatcctg tcttgcgaat catctccagc atttatatcg aatttgtgcg caacgttccc
    23821 aaccttctct ggatttttac tatctttttg gtgttcaaaa tgaaatccac accagcaggt
    23881 attacagcct ttactctctt tacatcagca gccttggctg agattattcg aggcggtctc
    23941 aatgccgtag acaagggaca atacgaagca ggaatgtcac aaggcttcac ctcagcccaa
    24001 atcctctact acatcattct cccacaagcc atccgcaaaa tgctaccagc catcatttct
    24061 cagtttgtta ccgtgattaa ggataccagc ctcctctact ctgttatcgc cctacaagaa
    24121 ctctttggag ccagccaaat tctcatgggc cgttatttcg aaccagagca ggtcttcagt
    24181 ctttgcatcc tgattgccct catctacttc agctttaacc tagcaatttc tagcctgtct
    24241 catatgctag ccaaacgttg gcaacaagct gcaga
//
LOCUS       DAYYYC010000030        22476 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.030, whole genome shotgun sequence.
ACCESSION   DAYYYC010000030 DAYYYC010000000
VERSION     DAYYYC010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.030"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(355..1551)
                     /gene="tuf"
                     /locus_tag="ACHBV5_001304"
     CDS             complement(355..1551)
                     /gene="tuf"
                     /locus_tag="ACHBV5_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFM9967094.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2462..3331)
                     /gene="gla"
                     /locus_tag="ACHBV5_001305"
     CDS             complement(2462..3331)
                     /gene="gla"
                     /locus_tag="ACHBV5_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HFM9967095.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3555..4163)
                     /locus_tag="ACHBV5_001306"
     CDS             complement(3555..4163)
                     /locus_tag="ACHBV5_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFM9967096.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPEKPIPQPNPEHPSVPTPNPELPNQETPTPDKPTPEPGTPKTETPVNPDPEVPTYE
                     TGKREELPNTGTEANATLASAGIMTLLAGLGLGFFKKKEDEK"
     gene            complement(4121..5227)
                     /locus_tag="ACHBV5_001307"
     CDS             complement(4121..5227)
                     /locus_tag="ACHBV5_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HFM9967097.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGRQEKLVESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5338..5592)
                     /locus_tag="ACHBV5_001308"
     CDS             complement(5338..5592)
                     /locus_tag="ACHBV5_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967098.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5586..5828)
                     /locus_tag="ACHBV5_001309"
     CDS             complement(5586..5828)
                     /locus_tag="ACHBV5_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967099.1"
                     /translation="MVQNEDLYKKGLNVELAHQQIKGFFEAEFKNRINGVLNTKIKNS
                     TLNRVNKKTIHQSNKNSMINLKQKQRKMLKNKAILC"
     gene            complement(5932..6776)
                     /locus_tag="ACHBV5_001310"
                     /pseudo
     CDS             complement(5932..6776)
                     /locus_tag="ACHBV5_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078372828.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            7010..8728
                     /locus_tag="ACHBV5_001311"
     CDS             7010..8728
                     /locus_tag="ACHBV5_001311"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFM9967100.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            8839..9186
                     /locus_tag="ACHBV5_001312"
     CDS             8839..9186
                     /locus_tag="ACHBV5_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFM9967101.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFVGL"
     gene            complement(9465..10301)
                     /locus_tag="ACHBV5_001313"
     CDS             complement(9465..10301)
                     /locus_tag="ACHBV5_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM9967102.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10314..10943)
                     /locus_tag="ACHBV5_001314"
     CDS             complement(10314..10943)
                     /locus_tag="ACHBV5_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFM9967103.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(10953..11594)
                     /locus_tag="ACHBV5_001315"
     CDS             complement(10953..11594)
                     /locus_tag="ACHBV5_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFM9967104.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11740..12969)
                     /locus_tag="ACHBV5_001316"
     CDS             complement(11740..12969)
                     /locus_tag="ACHBV5_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFM9967105.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(12959..14125)
                     /locus_tag="ACHBV5_001317"
     CDS             complement(12959..14125)
                     /locus_tag="ACHBV5_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFM9967106.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFIAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14269..15282
                     /locus_tag="ACHBV5_001318"
     CDS             14269..15282
                     /locus_tag="ACHBV5_001318"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HFM9967107.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15327..15746)
                     /locus_tag="ACHBV5_001319"
     CDS             complement(15327..15746)
                     /locus_tag="ACHBV5_001319"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFM9967108.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(15757..17163)
                     /gene="atpD"
                     /locus_tag="ACHBV5_001320"
     CDS             complement(15757..17163)
                     /gene="atpD"
                     /locus_tag="ACHBV5_001320"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFM9967109.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17249..18127)
                     /locus_tag="ACHBV5_001321"
     CDS             complement(17249..18127)
                     /locus_tag="ACHBV5_001321"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFM9967110.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18143..19648)
                     /gene="atpA"
                     /locus_tag="ACHBV5_001322"
     CDS             complement(18143..19648)
                     /gene="atpA"
                     /locus_tag="ACHBV5_001322"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFM9967111.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGYGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19663..20199)
                     /locus_tag="ACHBV5_001323"
     CDS             complement(19663..20199)
                     /locus_tag="ACHBV5_001323"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFM9967112.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20199..20693)
                     /gene="atpF"
                     /locus_tag="ACHBV5_001324"
     CDS             complement(20199..20693)
                     /gene="atpF"
                     /locus_tag="ACHBV5_001324"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFM9967113.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20707..21423)
                     /gene="atpB"
                     /locus_tag="ACHBV5_001325"
     CDS             complement(20707..21423)
                     /gene="atpB"
                     /locus_tag="ACHBV5_001325"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFM9967114.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNILEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21458..21658)
                     /locus_tag="ACHBV5_001326"
     CDS             complement(21458..21658)
                     /locus_tag="ACHBV5_001326"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HFM9967115.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(21733..22476)
                     /locus_tag="ACHBV5_001327"
                     /pseudo
     CDS             complement(21733..22476)
                     /locus_tag="ACHBV5_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         6681 a         4829 c         4108 g         6858 t
ORIGIN      
        1 agtctagtat tatactcttc gaaaatctct tcaaaccgcg tcagcttcgc cttgtcgtat
       61 agatgttact gacttcgtca gttctatcta caacctaaaa acagtgtttt gagcagtctg
      121 cagctaactt tctataacaa aatgaaataa gaacaagaca aatcaatcaa gataatcaaa
      181 tcgatttcta agaatgtttt agaagtagat gtgtactatt ctagtttcaa tatattatag
      241 tttgctcttt gattttcatt tagtattagt tcaatatcta aaaaaagaac cttgccaagc
      301 aagattcttt tagtgtctga cttaaataat tgttcttctg ggaactaaat cgaattaagc
      361 ttcgatttct gtaaccatac ctgaaccaac agtacgtcca ccctcacgga tagagaatgt
      421 agtaccttgt tctacggcga ttgggtgaat caactcaaca tcgattgtca cgttatcacc
      481 aggcattacc atttcagtac ctgctggaag ttcgattgaa cctgtaacgt cagtagtacg
      541 gaagtagaat tgtggacggt agttgttgaa gaatggagtg tgacgtccac cttcttcttt
      601 agtaaggatg tagacttcac ctttgaattt agtgtgtggg ttgattgaac ctggtttagc
      661 gataacttgt ccacgttcga tttcatcacg ttgaacacca cgaagaagga cacctacgtt
      721 atctccagca agaccttcgt caagttgttt acggaacatt tcaacaccag taacaactgc
      781 tttttgagtt tcttctttga taccaacgat ttcgatttcg tcgttgactt taacgatacc
      841 acggtcgata cgtcctgaag caactgtacc acgtccagtg attgagaata cgtcctcgac
      901 tggaagaagc aatggtttgt cagtgtcacg ttctggttct gggatatact catcaactgt
      961 gttcatcaat tccataacga tgtcttcgta tttagagtca ccttcaagag ctttaagtgc
     1021 tgaaccttgg ataactggaa gatcgtcacc tgggaagtcg tattctgaca ataggtcacg
     1081 gatttccatt tcaaccaatt caagcaattc ttcgtcgtca accaagtcaa ctttgttcat
     1141 gaagacgata aggtgtttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg
     1201 tggcattggt ccgtcagttg aagctactac aaggatagct ccgtccattt gagcagcacc
     1261 agtgatcatg tttttaacgt agtccgcgtg tcctggagcg tcgatgtgag cgtagtgacg
     1321 tttttcagtt tcgtactcaa cgtgcgcagt gttgatagtg ataccgcgtt cgcgttcttc
     1381 tggagcagca tcgatagacg catagtcttt aggttggtta actgatgaag gcaagcgacg
     1441 tgccaaaaca gttgtgatag ctgcagttag ggtagtttta ccgtggtcaa cgtgtccgat
     1501 agtaccaatg ttaacgtgtg gtttactacg atcgtatttt tcttttgcca tttgagtaaa
     1561 agcctccaat aaaatatatt ttatagatag acagtaggca atacagtcta actttcctta
     1621 ctattttatc aaatttcagc taaattgcaa gtgttttaca acgtttttgt gaattattct
     1681 tggtaaaaat ttaactaact aatagaaagt actaaataga cttatccttc aaggagtttt
     1741 cagcattatc catccactca cttgctgaaa atgtaaacag tctctggttt atatagtaaa
     1801 atgaaacaag aatagggcaa atcgatcagg acagtcaaat cgatttctaa caatgtttta
     1861 gaagttaagg tgtactattc tagtttcaat ctactataca acctcaaaac tgtgttttga
     1921 acaacctgcg gctagcttct tagtttgccc tttgattttc attgagtata aaattgcaga
     1981 taaaacgata acaatcatag gactcagcag agtcaatgta ggtcgaagaa tagcccccct
     2041 aatcgcttat tttatagcaa aatgaaatag aaactgaaca ttttgttgag gaaggtaaat
     2101 caattcctca caatgtttga gaaagaaggg aggactattc caacttcaac ccactataaa
     2161 gcagacttac aagataggga acccatctcc gataatatat agtagaatga aaactgcaca
     2221 atttgattgg agaattcaaa ccaatttcta acaatgtttt agaaacaagg gtctattatt
     2281 tcaactgcaa cctactatag cccattgaag ctggaatagc ccactgagac ttctaaacca
     2341 ctgctggaga ggagtttgtt tagagtttct ttcatttccc taaaaaatca aaaagagaga
     2401 accagtctga tcctctctta cttatagatg gtgctcactc aaatgttaaa ggagctattt
     2461 cttagagata aaggaatttg aatacagcta ctgccgcaat tgctgctgcg ataggtgcta
     2521 ctactggtac ccaagaatac caccattttg aatcgccttt atgctcacca agaactgatt
     2581 ttggaaggaa agcatgaagg agacgtggtc ccaagtcacg ggctgggttc aaggcaggtc
     2641 ctgtaggtcc tccaagtgat gttaccaaag ccataacgag gaatccaagt gccaagtgag
     2701 ccacagaaag tcctgaagca gtgtgtggag ccacctgtgc tttaatagcc aagtcagaaa
     2761 aatcaactgt ttgtcctgct tctattgcct tttgtttcat gaattgaagc acttcagcac
     2821 caaagaagtt tttagtcaaa ccaagagctg caaagaacaa aacaaatgaa ccaacaaact
     2881 cattaatcaa accattgaca gttgctgcat agcgactttc ttttgtacca tggtcaatac
     2941 ttgaaatagt tgagaaagtt cccaagatgt tatttgggtt ttcagttttc aagtagaatg
     3001 gacggtatgt tgccacaact aaggcttggc caaagatagc ccccaagact tgcgcgataa
     3061 tgtaaggtac cacttgtgcc caagggaaaa gaccgctaac tgcaagccct agagtgaaag
     3121 cagggttgat gtgattccca gatacgttac caaacatcaa ggctgggatc ataaccccca
     3181 taccataacc aacagcgatg acgatccagc cactttggtg acctttcgta cctttaagtt
     3241 caacgttggc aactgcacca ttcccaagaa tgatcaaaat ggcagttccc aaaaattcag
     3301 tggcatactt cagtgcccat gtgaaatcca tttgctagat tctccttaaa attttttaga
     3361 tattccttat tttatcaatt tttaccctat ttagcaactg atttctggaa atatttttaa
     3421 aaaaatagga ttcatagttt cccagttcaa cagacttgta agcgttttta ttctttacga
     3481 aagacctcgt tctcaaaacc aggaaaaaag cccacatctg tgagcttttc ctggttccta
     3541 gattctaaaa tctattattt ttcatcttct tttttcttga aaaatcctaa tcctagacca
     3601 gctaacaagg tcatgatacc agcactagcc aaggtagcat tagcttctgt acctgtgttt
     3661 ggcaattcct ctctcttacc tgtctcataa gtcggaactt ctgggtctgg attcactgga
     3721 gtttcagttt ttggagtacc tggttctgga gttggtttat ctggtgttgg agtctcttga
     3781 tttggtagtt ctgggtttgg tgtcggaaca cttggatgct ctggatttgg ttgtgggatt
     3841 ggtttttctg gtgttgataa acggtcatac cttaccgtta tttctttatc actagagtct
     3901 gacgtaactt cttgtgattc aactgttgga atatctggat ctttgtactt gtcaatctta
     3961 ccagatataa cctcgtccca gtttcctgtt gtccattcac cgtaggttac aactcccgtg
     4021 accttgttct cagtttttgt acggcttaag gttacaggtt gaacaacatc ttcttttaca
     4081 ttttggttcg taactttatc aacgtaatga atgatacgcg ttatagtctt cgtctcagta
     4141 gaggttgctg ttttgggaac cactgtttcc tcaacattct cacggtagta atagtcaact
     4201 gttgcaccgt cttctggtac gcatttgcag gagttgctac caaggtgtat gttgttttcc
     4261 ttgtgataac tcggtcttct ttgtcctcag ttgttgtttt cccttcaata gtttttgatt
     4321 ctgtggtata ctcagaacct atcgctaaat cagcttttat aacagactct accaacttct
     4381 cttgcctacc ttctttatag taattggctg ttactgtagc agtggttggc gcttcgcttt
     4441 ctctataaac taaggtcact gttctacctt cgcttacaat attcccagtt aaacttgcag
     4501 aatttgtatc tgcttcttta aaagtataat attttccgtc agtagtagtc atgctactga
     4561 gttttttatc tgtgacattg tagctggtac caatcagttg ttttttattg gtaatgtagg
     4621 ttccgtcact ttctttttct ccaattccag tatcattttt caatgatagc aaacgccctt
     4681 gttcatcaac atagcgaact ttcacatttt ctgagattag ttctgccaat tctgaggttt
     4741 ttttcttttt cttgatttct tcggttattt tccctttctc ttcttcggga atatttagtt
     4801 ttggaatgat tttttcaaca acggttcgtg atggttccac agtatcttgg atgactgaaa
     4861 agtcagctag aattgggaga ttatactgaa cacggtgact ttgagtgttt actcctactc
     4921 tttcattatt ctctgaaaat acttgtacgg tataagaaac aacatctttt cctaatagaa
     4981 catccccagt agagaaatag ccgccttttc ctagtttgct atctccagag cccacttctt
     5041 tcctaatctt atcagatagt tttttaccag tcagtacatt cgttcgcaca atccctttgt
     5101 ctacccctac aaagtgggag aactttttga actcttcaga accagatcta gcccaaccat
     5161 tattaagggc atttgctttt gtatttgtat tctctctcaa aagtttggcg attagaatta
     5221 tattcatcgg cacttagagt tgctgctata tctgactctt gaataccaac ttccttacta
     5281 ccatttctag cggcagtata tgtgtattta tctgtttcta cttctagctg attatcctta
     5341 acatgatagg taattttctc ctggtataag agtcttcagt agtttatatg ctctgtcatc
     5401 atctttagct ttagaagcag ctgagtttag ccaagttggg gtattaggag tatctttatc
     5461 agcctgtttc aagacattat tcaagtcatt tgctagccta ttggttgtcc tcactgtgaa
     5521 agttttcttc cagtctgaac cacttttatt agacttagat atgctcatga aatcctggtc
     5581 aacattcaac acaatatcgc cttgtttttt agcatcttcc gttgcttctg cttcaaattg
     5641 atcatggagt ttttgttgct ctggtgtata gtttttttat ttacacgatt taatgtacta
     5701 ttttttattt tagtattaag aactccatta atacgatttt taaactctgc ttcaaaaaat
     5761 cccttaattt gttggtgcgc aagttcaaca ttcaaacctt ttttatacaa gtcttcattc
     5821 tgaacgattt cggctacacg gtgaatggtt tgattgtata ccgtcttctc ttaaccagca
     5881 gtatccttag ttttaatgac tactcgatag gttcctttag aaccgttata gtcatctagt
     5941 tttaaaaaag cattccaaac attcaaaaat agttggaact tcccttaata aatccgtcac
     6001 tttctttttc aagatagccc aagcttgctc aataggattc aaatccggtg aataaggtgg
     6061 tagaggtaag aaaaagtgtt tatcttggat gcagagttca tccaaaatgt tcttgggatg
     6121 aaaaccagca ttgcccatga caataacatg aggtgtcttc aaagcaggta ggagttgcgt
     6181 tttgaaccac tccacaaaga aatcgcttgt catgcttttc ttgtaaatca tgggagctat
     6241 aaactctccg tctacttgtc ctgcaacaat tgaaattcgc tcaaaacgac gtccgctaat
     6301 cttttcatag actttctccc ctctaggagc ccctgcataa ggacgataga gatagcggtc
     6361 gattcctgtt tcatcaatat aaacaggtgc taggtgcttt aaactattaa aattcttaag
     6421 aaataaggct acttttctgg gtcttgttcc ttaaagctcg tcatcttttt ttaaagtgac
     6481 cttaatctgc tttaaagctg cccatactga aggaacagca caatcaaaat gtgccgcaat
     6541 ttcccgtaaa aaagcatctg gatgagcctc tacaaaggct ttcaattcct ctaaaggaat
     6601 ctttcggttt ttgacgactc gctttttcct ctctatgtgt tcttgttcac gtctttcttt
     6661 tcccacgtga agagagttct gacgccaaca ccaaaaaact tggctgcctc gacatggctg
     6721 tgcccctctt tgatgtaatc taatgctcgc tgtttaaaat cagtactata tgccatagct
     6781 ttattataat atgcttgttt aaaactaagt aactatatca atgttttgtt atgagaagac
     6841 ttactttttt tactgaaatt gaatttttcc tagcctaaac atcatataac cccaaaattc
     6901 aatctgacct ggtttgaaga gattttcgaa gcagataagg ttttactaaa actaaaaaaa
     6961 atgatataat caaactgatt aaatgtttta aaaataaagg agaatttgaa tgtcttacca
     7021 agaaaattac cagaaatggg ttgattttgt ggagcttcct gactaccttc gtcaagattt
     7081 ggaaaatatg gacgaaaaaa ctaaggaaga tgccttctat acaaatcttg aatttggtac
     7141 tgcaggtatg cgtggcttgg ttggtgctgg tacaaaccgt atcaacatct acgttgttcg
     7201 ccaagctact gaaggattgg ctcgtttgat tgagtcaaaa ggtggaaacg agaaagaacg
     7261 cggtgtagca attgcctacg atagccgtca cttctcacct gagtttgcct ttgaatctgc
     7321 ggcagttctt gctaaacacg gcatcaaatc ttacgtattt gaaagccttc gtccaactcc
     7381 agaactatca tttgcagttc gtcatctcaa ctgtttcgca ggtatcatgg tcacagccag
     7441 ccacaaccct gctccattta acggttacaa ggtttacggt gaagacggtg gacaaatgcc
     7501 tccacacgat gcggacgctt tgactactta tatccgtgca atcgaaaacc catttgcagt
     7561 tgaagttgct gatgtggaaa ctgaaaaagc ttctggcttg attgaagtta tcggcgaagc
     7621 tgttgacata gaatacctta aagaggttaa ggacataaac atcaacccag ccttgattga
     7681 agaatttggt aaagacatga agattgtcta cacaccactt catggtactg gtgaaatgtt
     7741 ggctcgtcgt gctcttgccc aagcaggatt tgactctgtt caagttgttg aagcgcaagc
     7801 aactgctgac ccagacttct caactgtaac atctccaaac ccagaaagcc aagcagcctt
     7861 tgcccttgct gaagaacttg gtcgtcaagt tggtgcagat gttcttgtcg caactgaccc
     7921 agacgctgac cgtgttggtg ttgaagttct tcaaaaagat ggcagctacc tcaacctttc
     7981 aggtaaccaa atcggtgcta tcatggctaa atacatcttg gaagctcaca aaaacgctgg
     8041 aactcttcct gaaaatgccg ctctctgcaa atctatcgtt tcaactgact tggtaacgaa
     8101 gattgctgaa agctacggcg caactatgtt caacgtcttg acaggtttca aatttatcgc
     8161 tgaaaaaatc caagaattcg aagaaaaaca caaccacact tacatgatgg gatttgaaga
     8221 aagcttcggt tacttgatta aaccatttgt acgtgataaa gatgccatcc aagccgttct
     8281 tgtagttgct gaacttgctg cctactaccg ttctcgtggt ttgacacttg ctgacggtat
     8341 cgaagaaatc tataaagaat atggctacta cgcagaaaaa acaatctctg ttactctttc
     8401 aggtgtcgat ggtgctgaac aaatcaaagc gattatggct aaattccgca acaatgctcc
     8461 aacagaatgg aacgcaacag ctatcactgt cgtagaagac ttcaaggcac aaactgctac
     8521 tgttgctgac ggtactgtta caaacttgac aactcctcca agtgatgtgt tgaaatacac
     8581 acttgctgac ggttcatgga ttgccgttcg cccttcaggt acagaaccaa aaatcaagtt
     8641 ctacattgca gttgtagggg aaaccaacga agaatcacaa gctaagatta ctaacatcga
     8701 agcagaaatc aatgcatttg taaaataaag acctataaaa gatgagacca accaacctca
     8761 tcttttttcg tatcaaatct aagcaatttt agaaacttta tggcatacta gacttatcaa
     8821 tgaaagcgag gtaatctcat ggaacaattt ttagataaca tcaaagacct tgaagtcact
     8881 acagttgtgc gtgcgcaaga agctcttgat aaaaaagaaa ctgcaacctt ctttatcggt
     8941 cgcaaaactt gcccttactg ccgtaaattt gcaggtacat tgtcaggtgt cgtagctgaa
     9001 accaaagctc acatttactt catcaatagt gaagaaccaa gccaactcaa tgatttgcaa
     9061 gcattccgct cacgttatgg aatcccaact gtaccaggtt ttgttcatat tacagatgga
     9121 caaatcaacg tccgttgcga ctcttcaatg tcagcacaag aaatcaaaga tttcgtagga
     9181 ttgtaaaaaa tcagctaaca agtcttaaaa tcacaaaaac gcataatgta aggtgcaaaa
     9241 accttgatat tatgcgtttt attgttccta aaacagttac atcagtattt cattacagaa
     9301 cattttaatt ttggaagtca aatcaatttt taacaatgtt ttagaaatca cagtgggcta
     9361 ttccatattc aattatccag attcaatcgc tattatcgtt ttcctagatt acaaaaaaaa
     9421 ctacgttttg ctaatcaaaa cgtagtctca gccactattt tatcttactg tccttctttt
     9481 acttctttgg ttgctacatc ttctccaaac catttttggc tgatttcttg gaacttgccg
     9541 tccttgtaaa gactagaaaa agcttcattt atcttcttaa ccaaggttgt atcttcctta
     9601 cgggctccaa ccgcaaaagc ttctgtttct agtccaactg taaagacatt ataatcgttt
     9661 aaaacacctt ctgcttctaa ataatagttt gcatagacac ggtcaatcaa tagaccatca
     9721 attcgatcgt ttttcaaatc aatcaaggct tcattaaagg tttggtattg attcgcttcc
     9781 ttattagcga caatattctt caaaagttct ggatttgctt caaagtccgc ataaccagat
     9841 gaaccagctt gagctcctaa tgtctttcca gtcatatcct ttgcagtcgt gataccagat
     9901 gatttcttcg taaccaatac ctgctcattc ttcatatatg agttactgaa agccaccttt
     9961 tcacggcgtt cgtctgtagc ggaatagcca ttccaaatca gatcaatcgt tccttttgtc
    10021 aattcagctt ctttcaaatc ccaatcaatc ggttgccaat ttaccgtgat tccgtatttt
    10081 tcaaaaacag ctgtagctaa atcaatatca aatcctgcat aagaaccatc tttctgagca
    10141 aatcccattg gaacaaaagt actatcaaat ccaatagtaa tagacttgtt agactggtac
    10201 tttgaccaat tatctccact agtttcgcta gaatttttcc cacaagctac taagaacaaa
    10261 gcagtcatca gactgactaa tacaagcatc cattttttca tccatttttc ctcctattta
    10321 ggttctactt tcaataatac atctgcgata ttttcagcaa actgcaaatc atgggtaacc
    10381 acaatctggg tcatcccaag ttccctattt tgcaagatta gcttctccac ttccaaacgt
    10441 aattctggat ccagggcaga agttggttca tcgtagccaa tgatttctgg gtcaatcatc
    10501 atagcacgcg ccaaagccac tcgctgcttt tgcccaccag atagtgagaa aggataggcc
    10561 tctgcgtgtc ctcctagtcc taactgttcc aagagtccac tcgccttctt ctcagcctct
    10621 tcctgcttca ttcccatggt cttcacaggc gataaagtca aattttccag aactgataga
    10681 tgaggaaata gttgaaaatc ttggaagaca aatcccagta ggttgcgctt ctgcaattca
    10741 tccagctcta aaggttgtcc attataaaag atttgccctg aatcaatggt ttcaagacct
    10801 gcaagcatac gtaaaagagt tgtcttacct ccaccagaag gtccaacgat agccaggatt
    10861 tgcttttcag gaatacttag actgaaatta gacaggattt gtttgtctcc aaagacttta
    10921 ttgatatttc gtaattctaa catggcagcc tcctatctat aataactata cttcttctca
    10981 acttttttgg aaataattgt cacaatccca atcaaaatca aataaatggc tcctgccaag
    11041 aacataggaa ccagactagc atcgcggtta gcagctgttc gactagccaa gataaggtct
    11101 gaaattccga gagcatagac caaagaagta tccttgacca aactcataac ttcattaaag
    11161 acactaggaa gaacgatctt ggtcacttgg ggcaagataa tatagcgcac tctgtcaaaa
    11221 gggctaaact tcaagacctt ggcagcctca tactgtcctc ttggaatagt gtcaattccc
    11281 ccacggaaaa tttctgcaaa gtaagccgca taattcaaaa caaaggcaat aatagctgca
    11341 ggaaggcggt ctaaacgaat cccaatactt gggagcacat aatagataaa aatcagttgc
    11401 aagagtaagg gggttcctcg cataacccag atgtaaatgt taatcagata atggaggggc
    11461 ttccaatgga cttgcaaggc aaaggcaatc aaaacgccca agggaatcga aaatagcaag
    11521 accagtgcaa agacctgtac agtcgtgctc gcaccattca gtaaactcgg taatatctca
    11581 aataaataag acatactgca cctcctaaaa gtaattgttc ctattatagc atgaataaac
    11641 aagattacca agtatttttg taaaaagatt ctaccatata caaataaaaa ccgtagctat
    11701 caaaagagat aaactacagt tctatatgtt taaacattct tacaatctct caaacagttc
    11761 ttgcatttgc acatcatctg gaaccagttt taagtaagtg tgagcatgga cttttgcttc
    11821 ttcaaaatgt cccaattcac gcaagagata gatatagtgt tccagaaatt ctggattgtc
    11881 cttcaaatct cctgtcaact cttgataatg ctcataagca gtatccaaat cgtccatttc
    11941 ttgataagaa cgagcaatca tccacttggt caaaagattt tctggctcct cactctgcaa
    12001 gtctagaata tcctcataac gctcctgctc cagataaata gtggctaaac gaagcaagat
    12061 ttcttctgta tcctcagcgt cttcttttgc agtaaggaga taattttctg caccactagc
    12121 atcatgcaat tcataagaaa attgtgaagc agctagcaag aggcgagttt caaagggatt
    12181 tttctctaat ccttgcttag cgatacgcag ggcttcttga acttgatgtt ccttatgtaa
    12241 agcctgactg tacccatact catagccttc aaagtcagga gaaatggtat caagctgctt
    12301 aaagtagagg gtggcttttt gatattcttc ttgatcaaaa taaagactgg ccaactcaaa
    12361 agctgttaag tcatcgtatt ctaactccag ggctttttct aaaaactcag tagccgtttc
    12421 aaatttccct aactgagcat aggcaaagcc aattcgttga taggtggaaa tgcccgtttg
    12481 ctcataaatc gagcgattat ctaactgggc ataggcttga atagccgctt ggtaattttc
    12541 caactcacta tccaactctg ccaaacccaa tatcaagaga gaatcctctg agtaggtcaa
    12601 ggcctccaat aatttctcac gtgccacatc tgtcaaacct tccagctggt aaaggtctgc
    12661 cttcagagcc aaagacgaga cataccagtc actgtcagct tggatttcct caagataggt
    12721 aaaggcttct tctatttgac catcctcgct agcaattgca gctagattaa gatgaacctc
    12781 tggaaaatcc tctacaattt tcaggtaaat ttccttggcc tgaggataga aaccaatccc
    12841 ttcaagataa gttgccaact catacagaag atcacttgaa tcattttcta aagctttggc
    12901 gaaataatgc tcagccttag ttaaatcttg ctcctccaaa gcctgtaaca tctgttgact
    12961 attgttcact cttgacttcc tcaccctcta attcatatag accactgact accttatacc
    13021 attcgaaaat ggctgaaatg acaaccttag cagaggcata aaccggaata ccaagtaaaa
    13081 ctccccagat accaaacata gatcctgaag ttaacaaaac aaagagaaca ttaataggat
    13141 ggatgtttaa ttgacttccc aaaatcaatg gagagacaaa acggccttca atagtttgtt
    13201 ctacaataaa gacaatcact actttcaaaa gcatgactgg accagcaatc aaacccaata
    13261 ctagggcagg aagcatggct agaaagctac caagataagg gaccagattt aaaataccag
    13321 cagtaacccc cagcgtaacc gcatagcgta gaccaataat cttgaagaag atgataaaca
    13381 ttactgctac aataatagcc actgtcactt gccctcgaac atagttggac aactgttgat
    13441 tcacatctga tagaacttgt ccaacaggtt ccttcaattt tcttggaatg aattgggtca
    13501 aatagttacg caagcctttc ccatcacgca agagataaaa gagcatgaaa ggaacgataa
    13561 tcaaggcaac aatcacttga gaagctccgc taataaaggc actcacccag ttgactgcct
    13621 gagatgaaac cttacttgcc aaaactgtag cctggctaga aaaattggtc aaaacttgct
    13681 ctaattgagg tctgaaatca tctggcaggt gctgggctac caatccatta acaatcctat
    13741 ctatatcttc taagtaaaca ggaacgtttc ttgcaaaggt caaaacctga cgttgcagat
    13801 ttggaatggc gactgccaag ccccaaatga taaagagagc gatgataaca aagacaatag
    13861 tgatagctat aacacgatta accttatgct tctccatcca atcaacaata ggattcaaca
    13921 aataatataa caaaccagac aaaatgactg gcaacatcac aactgctata aagtctaaaa
    13981 caggtgaaaa tagaaaacta atcttactta aaataaaaag attcaatccc aataataagg
    14041 ttactaaaaa taccgtaatt gccttgttat ctaaaaacca cttgaaaaac caagataggc
    14101 taaaatgttt ctctttttgc tccataaata cttcctttct attgttctct cattatacca
    14161 tttttgaaac aaaataactc ttttttaaag tgcttacatc taattgaatg tctttaattt
    14221 gcttgttttt gtgatataat agtcttatct ttacacagag gtatagtaat gaaagaaact
    14281 gtttattttg gaacttatac acgtcgtact tctcaaggga tttacaaggc agactttgat
    14341 acagaaactg gtcagctttc aaatctagaa ctttttgcag ctgagccaag tccaacctac
    14401 cttgcctttg accagcacca acatttatac actgttggta gccaagacga taagggggga
    14461 attgcagcct atcaaactga cgggactgtg ttaaatcatg ttgttgaaga aggagctccc
    14521 cactgttatg ttgctgtcga tgaaaagcgt gatttggttt acgcagccaa ctatcacaag
    14581 ggacaagtcc ttgtttataa acgccaggaa gatggtagtc ttctacttag tgatatggat
    14641 caacacagtg gccaaggtcc acatgaaaat caagcttccc cccatgttca ctatacagat
    14701 ttaacacctg accactatct agtgacctgc gacttgggaa ctgaccaagt catcacctat
    14761 gacctcgatc aagaaggaaa attatctaag ctctatacct atcacagcaa gccaggagca
    14821 ggctcacgcc atatcatttt ccataaccac tataaaatcg cttatctcat ttgtgaactc
    14881 aatagtacta tcgaagtttt aatctacgat ggcgttggcg aatttgaacg tatgcaggtt
    14941 atttcaactt taccagaagc ttacgaaggc tttaatggaa ccgctgctat tcatctctct
    15001 aaagacggta aatacctcta cgcttctaac cgtggccatg attctatcgc agtatatacc
    15061 atccttgcgg acggtagctt agagttatta gaaatcgttc caacgcatgg tcagactcca
    15121 cgtgattttg atttgacacc cgaccaaaaa tttctcattg ttgtccatca agactctgac
    15181 aatgcaactg tctttaaacg taattgtgac aatggtcgtc tagcagaact ctccaacgac
    15241 ttccatgttc ccgaagcagt ctgcatccgt tttgctcctt aaaacaccat aaaaaatgaa
    15301 cttggtattt tcaagttcat tttttcttat agtctatttc cgacattaat acggttaata
    15361 gcacgttgca aagcaatctt agcacgacgt tcttggtcaa tcaaatgttt gtcttgtgct
    15421 tcttcaattg cacgttctgc acgaagtttg gcacgttctg cacgactgat atcgatatca
    15481 cgagcacgtt ctgcagagtc agcgacgatt gtgatcatat cattggcaat ttcaataacg
    15541 ccaccgttta ctgcaatcca gttcacgtga tctttatcat cgatacgttt tacctttact
    15601 tcatcaactg ctaaaaccgc aatcatattt tcatgtcgtg gcaagatccc catctcacca
    15661 tccagagttc gaaccgatac atagctggca tggtgatcat agacgagacc atctggtgtc
    15721 acgatctgga cagttaactg agccatagat cacctcttaa aatcccattt tttcagcttt
    15781 tgcaatcaca tcttcgatag aacctacacc acggaaggca tcttctggca agtggtcgta
    15841 tttaccatca aggatttcct taaagccacg tacagtttca gcaactggaa cataagaacc
    15901 tggctgacca gtaaattgtt ccgcaacgtt gaagttttgt gacaagaaga actggatacg
    15961 acgggcgcga gcaaccaagg tcttttcttc atcagaaagc tcatccatac caaggatagc
    16021 aatgatatct tgcaattcat ggtaacgttg aaggacacgt tttacttcag cagcaactgc
    16081 atagtgctct tctccaacga tttcaggtgc caaggcacgt gagcttgaag caagtgggtc
    16141 aacggctggg tagataccca attgtaccaa cttacgttcc aagtttgttg ttgaatccaa
    16201 gtgagcgaag gctgttgctg gcgctgggtc agtatagtca tccgctggca catagatagc
    16261 ctggatagag gttacagaac ccttcttggt tgatgtgata cgttcttgca attgacccat
    16321 ttccgtagca agtgttggtt ggtaaccaac ggctgatggc atacgaccca aaagggcaga
    16381 tacttctgaa ccagcctgag tgaaacggaa gatattatcg ataaagagaa gcacgtcttg
    16441 gccttccaca tcacggaagt attcagcgat tgtcaaacca gtaagggcaa cacgcatacg
    16501 tgctcctggt ggctcattca tctgaccaaa gaccatggct gttttctcga taacgcctga
    16561 ttctttcatt tcccagtaaa ggtcattccc ctcacgagta cgttccccaa caccagtaaa
    16621 tactgaaata ccaccgtgct cttgggcaat gttgtgaatc aattcttgga ttaagacggt
    16681 tttaccaact ccggcaccac cgaaaagtcc aactttacca cctttaaggt aaggggcaag
    16741 aaggtcaata accttgatcc ctgtttcaag gatttcagaa gaggtagaca actcatcaaa
    16801 agttggagct tttttatgaa ttggctgacg ctctgcgtct tctgtaaaag gagcttccaa
    16861 atcaatggta tctcccaaaa cgttgaagac acgtcccaaa gtttctttac ctactggtac
    16921 agagattgga cgacctgtgt ccaatacttc cattccacga gtcaacccat ctgttgattc
    16981 catggcgata gtacgaacca taccatctcc taactccaag gctacttcaa ggacgatttt
    17041 tgtttttctt tcgtcatttt tgtagacgac aagtgcattg ttaatctcag gaagtttttc
    17101 ccctgctgca aacaaaacgt ctacaacggg accgataacc tgagcaattt tacctgaact
    17161 catctccttc tcctattcta tataagatac tgtcggttcc tagctcaact aggtcctaag
    17221 ttcattttca tacgagctgg actagagcct attctaaggc actagcacct gctacgattt
    17281 ctgtaatttc ttgtgtaatc gccgcctgtc tggcacggtt atactgaatt gtcaaatcat
    17341 tgatgacttt cttagcatta tctgtcgctg tttgcatggc tgtcataccc gcagcattct
    17401 cagctgtctt ggcatcgata atggcaccgt aaatcatact ttctgcaaac tgaggcaaca
    17461 actgctccag aatttcttct cggctggttt ccaattcaaa agtcaagctg tactcttcat
    17521 ccgcttcatt tggatccaag tcaacaatcg gaagcatttg ttccacacgc atttgactgg
    17581 ttagcgtatt gacatggtgg ttgtagcaaa cataaagctc atcaaagagt tcattttggt
    17641 acatttcaac agtttttgaa ataatcttac gaacttgatc aaagctaggt tggtctgcca
    17701 agccacgtaa ttcataaagt ggttgaatac cgcgagcctt aaagaaatca gctcccatcc
    17761 caccgataca gatcatttca aaacctttac cgtctgggtg gtattcttct ttcaactcca
    17821 taacagcttt caaaatagag gaattataac ctccaaccaa accgcggtct gaagtgataa
    17881 cgatatagcc tgtcttcttc acagaacggc taatcaacat cggattagtt gaagcaccag
    17941 ctccattacc atgaaggata tctgtcaaaa gtttacgcac tttctgagcg taaacttgga
    18001 agttgcgagc agcttcttca gagcgaccta acttagcagc cgataccatt tgcatggcat
    18061 tagtgatttg actcgtattt tttgttgagg cgatttttgt tttaatatca tttagagaca
    18121 ctgccatctg acacctctat tcttattgga agctagattg attgagaaac tctgtaatcg
    18181 cagcatccaa gactgcttct tctggcaagt cttttgtatc acgaatggtt tccaaaatct
    18241 ctggatgttg agcatcaaag aaggcatgga actcttcctc gaaacgaaca atatcatcta
    18301 ctggaacagt atccaagaaa ccatgtgtca aagcataaag aatggttact tgtttctcaa
    18361 caggtaatgg tttgtgaaca ggttgtttca agacctcaac ggtacgacgt ccacggttca
    18421 acttagcctg tgttgctgcg tccaagtcag aaccaaactt agtaaaggct tccaactcac
    18481 ggtatgaagc aaggtcgata cgaagtgtac cagcaacctt cttcatggct ttgatttgtg
    18541 cagaaccacc tacacgagat acagatgaac ccgcatcgat ggctggacga atacctgcat
    18601 tgaagaggcc atagccaagg aagatttgtc catcagtgat agaaatcacg ttggttgcga
    18661 tataggctga gatatctcct gcttgtgtct cgataaatgg tagggctgta attgatccac
    18721 caccaagttc atcagaaact ttagctgagc gctcaagcaa acggctgtgg agatagaaaa
    18781 catcccctgg gaaggcttca cgacctggag gacgacgaag caagagcgat agttcacgat
    18841 aagctaccgc ttgttttgat agatcatcgt atacaatcaa aacatgctta ccttgataca
    18901 taaattcttc cgccatagca accccagtat aaggagctag gaagagcaat ggagatggtt
    18961 gtgaagcaga ggctgtcaca acgattgtgt agtccaaggc accgtactga cgaagtgttt
    19021 ctacttgcgt acgaactgtt gattcttttt gtccaatcgc gacgtagata cagatcatat
    19081 cttgatcttt ttggttcaag attgtatcaa tcgcaatggt tgttttccct gtctgacggt
    19141 caccgataat caactcacgt tgaccacgac caatcggtac aagggcgtca atagctttca
    19201 aaccagtttg caatggttct gaaacagact tacgttgcat aacaccagga gctggtgctt
    19261 ctactggacg agttttatca gtgtggattt ctccaagacc gtcaactgga cgaccaagcg
    19321 gatccacaac acgaccaatc agactttcac ctacagggac ttccatgatt ttccctgtac
    19381 ggcggattgt atcgccttca cggatatctg taaagtcacc taggatgata ataccaacgt
    19441 ctgttgactc caagttttga gccataccat aagagccgtt ttcaaaattc aacaactctc
    19501 cactcatgac attttcaagg ccatgagcac gcgcgatacc gtccccgata taggttacaa
    19561 cacctgtttc agtcacatca aaattgggtt tgaaattttc aatttgttgc ttaattaaag
    19621 cgctgatttc ttgtgcgtta attgccaaaa gaacaccact ttctatttca aattttcttt
    19681 aacaacttta agttgttgtt taatactcac atcaattgtc ttgtgattgg caaaaatgac
    19741 aaaaccacca atgagacttt catcgatttg ttcttttaca ctccttactt tcagagacat
    19801 ttttttctca atcaaaggga gcaaacgagt cttctgttca tcagttagag gatgagcaga
    19861 cgtaatcgtc acttcaaatc gatttgtttc tttttcaagt cggttcaagc aatctacaag
    19921 cacatcataa aaaagatttg ctctgtgatt gtaggccaga acctggataa agttttgtaa
    19981 taaaggcgac acagaatctt ggaaaaaagc aattgttttt tccttatccg actcgtctac
    20041 tgccacttgt tttaaaaaag aaggcagacc tgttttttca acaacttgct tgatttgagt
    20101 caagtctgaa aagatacggt cttcttctcc tttttcaagt accaattgga caaaaggcat
    20161 gctgtatttt tcaattacct ttactgtttt cttgtccatt aagcttctcc tagctgatcg
    20221 atatactgat caatgagtgc tttatgggca tgactgtcaa ggttttgtga gatgatttta
    20281 ccagctaagc tgatggtcaa atctgcgacc tcacccttaa cactctgtaa agcttctact
    20341 ttattttgag caatttcttg attggctttt tcttttaagt gtcctgcttc tagtttagca
    20401 tctgctaaga tattagcctt actttgctca gctgtttcct ttgcattttc aatgattgtc
    20461 ttagcttctt tacggctacc agccaattca tcttcgcgtt tttgagccaa tacttctgct
    20521 ttttgacggg cttcttcagc tctatcaata tctgaagcaa ttttttcagc tctttcttcg
    20581 aaaatgcctg taatattaga ccatgcaaat tttttaatca agactagcaa aagaataaaa
    20641 gagccagtga ttaaaataaa attaccaatt aattcaccta ctgttacgtg catcagttac
    20701 tcctttctat tcctcttcaa tattaatctt attccctaaa tacacagatg tcaaaagagt
    20761 aaaaacataa gcttggatgc aggaaataaa gacagaaaat gcagtccaag ccaaattagc
    20821 tccaaaggct actggatacc aataaatagc ttggtgggaa agaagaagta acaaactcgt
    20881 catgacctct cctgcaaaga tattcccaaa aatccgcaaa gccaaagata agaagtttgt
    20941 aaattcttcc aagatattca tcggtatgac aaaaacagga ctcataaaag attttatact
    21001 ttttttaaat ccacgacgac gaacgctttc tatatgtgtc aacaaaatga caagaaaaga
    21061 taaggttaag tcatactgta aattagcggt tggcgaactc caccagttag tcccatcgat
    21121 cgtttgaagc tttgtcatta agccaaggtt attggcaatc accatgaaaa ggaataaaca
    21181 aaggaaaaag agtgagtaat ctttcatgta gcgcgaacca atgttaggtt ctgtaaatcc
    21241 aataacaaag tcatagacat actcaagtat attttgcttt cctttgggtt tcaaggtcat
    21301 attgcggctt gcccaataaa taaagacaaa aataactccc acaatcaaca aagtcatggc
    21361 taacatagtc agattgaaga taacaggacc aatagagatg attggattaa tactttcttc
    21421 catctaaaat cctccctttt cttctcgttc catgtattta tttgataata aatgagaaga
    21481 caagagttac aaagaaagtt ccttcaataa aggcaacacc taaaaacatc aaactacgaa
    21541 actcagaaag catatctggt tggcgtgcta ctgatttaaa cagtccattc atcaataaac
    21601 cttcaccgac agatacgccc atacaggcaa tacataagcc taaaaatgtt aaattcataa
    21661 caaattctcc tttaaaataa aatttactta cttagtgtag tcctaaaatt taaatttgtc
    21721 aacttttaac cgctattgga agcgtttaat aaaaattatt tccattttgc taaatttcaa
    21781 gttcaagtta gccatccaga agtcttctct gggtgacttg tagtccaagc attttttagg
    21841 atagttgtta atccactttt cgatgaatgc gacttctttg ggagtcattt tcttggttcc
    21901 cttaggtaac tatctacgaa tgagcctgtt gtgattctca ttagttcccc tttcccaaga
    21961 ggcatagggg tgcgcataat agatgtgctc ctcagaaaat atatcaaaca agcgattgaa
    22021 ttccgttcca ttatctgccg tgatggaaag aatcttgtgt tgttttaaga tgagttttag
    22081 agcctgattg accacctcag cacttttatt tggaatcaat cggatgatct gatgtctact
    22141 ctttcgatcc gtcaagacaa gcaagcagta gtttttcgct ctcgtaagta gaaccgtatc
    22201 aatctcataa tgcccattct ccaagcgaag attgatagct tcaggccgct gtgcgatgga
    22261 ttgaccagca ggtttaaagt tgatgctagc ctgtttctta agcgcttttc cttttctagg
    22321 gtaaagcaga tcctgtttgc ttaaccccaa ttttccatga tgaatccaat agtaaatggt
    22381 tgaaattccc acgttaaccc ctttagccat caccatcatt tcaggcgaaa atttttggtt
    22441 atgatagtgg agaatctttt cctttagttc cttggt
//
LOCUS       DAYYYC010000031        21460 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.031, whole genome shotgun sequence.
ACCESSION   DAYYYC010000031 DAYYYC010000000
VERSION     DAYYYC010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21460
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.031"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(537..2264)
                     /gene="ezrA"
                     /locus_tag="ACHBV5_001328"
     CDS             complement(537..2264)
                     /gene="ezrA"
                     /locus_tag="ACHBV5_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFM9967116.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPPQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2346..4292)
                     /gene="gyrB"
                     /locus_tag="ACHBV5_001329"
     CDS             complement(2346..4292)
                     /gene="gyrB"
                     /locus_tag="ACHBV5_001329"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFM9967117.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVYVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4307..4870)
                     /locus_tag="ACHBV5_001330"
     CDS             complement(4307..4870)
                     /locus_tag="ACHBV5_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFM9967118.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4955..5509)
                     /locus_tag="ACHBV5_001331"
     CDS             complement(4955..5509)
                     /locus_tag="ACHBV5_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HFM9967119.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(5520..6743)
                     /locus_tag="ACHBV5_001332"
     CDS             complement(5520..6743)
                     /locus_tag="ACHBV5_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFM9967120.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6780..9230)
                     /locus_tag="ACHBV5_001333"
     CDS             complement(6780..9230)
                     /locus_tag="ACHBV5_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HFM9967121.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVVLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9430..10359)
                     /locus_tag="ACHBV5_001334"
     CDS             complement(9430..10359)
                     /locus_tag="ACHBV5_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFM9967122.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10499..10786
                     /locus_tag="ACHBV5_001335"
     CDS             10499..10786
                     /locus_tag="ACHBV5_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HFM9967123.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10820..12154)
                     /gene="ciaH"
                     /locus_tag="ACHBV5_001336"
     CDS             complement(10820..12154)
                     /gene="ciaH"
                     /locus_tag="ACHBV5_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HFM9967124.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12144..12818)
                     /gene="ciaR"
                     /locus_tag="ACHBV5_001337"
     CDS             complement(12144..12818)
                     /gene="ciaR"
                     /locus_tag="ACHBV5_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HFM9967125.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12927..15473)
                     /locus_tag="ACHBV5_001338"
     CDS             complement(12927..15473)
                     /locus_tag="ACHBV5_001338"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HFM9967126.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEGLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15596..16036)
                     /locus_tag="ACHBV5_001339"
     CDS             complement(15596..16036)
                     /locus_tag="ACHBV5_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFM9967127.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQAHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16011..16880)
                     /locus_tag="ACHBV5_001340"
     CDS             complement(16011..16880)
                     /locus_tag="ACHBV5_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HFM9967128.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPSVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16922..17650)
                     /locus_tag="ACHBV5_001341"
     CDS             complement(16922..17650)
                     /locus_tag="ACHBV5_001341"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9967129.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17658..18137)
                     /locus_tag="ACHBV5_001342"
     CDS             complement(17658..18137)
                     /locus_tag="ACHBV5_001342"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFM9967130.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            complement(18148..18846)
                     /locus_tag="ACHBV5_001343"
     CDS             complement(18148..18846)
                     /locus_tag="ACHBV5_001343"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HFM9967131.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18839..19075)
                     /locus_tag="ACHBV5_001344"
     CDS             complement(18839..19075)
                     /locus_tag="ACHBV5_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFM9967132.1"
                     /translation="MTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTIEQNGLALEMT
                     PYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19171..20097)
                     /locus_tag="ACHBV5_001345"
                     /pseudo
     CDS             complement(19171..20097)
                     /locus_tag="ACHBV5_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
     gene            complement(20172..20987)
                     /locus_tag="ACHBV5_001346"
                     /pseudo
     CDS             complement(20172..20987)
                     /locus_tag="ACHBV5_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(20991..21311)
                     /locus_tag="ACHBV5_001347"
     CDS             complement(20991..21311)
                     /locus_tag="ACHBV5_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFM9967133.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6503 a         4698 c         3750 g         6509 t
ORIGIN      
        1 attactatta tataatactt tttttatttt agtctagtat aaatagcgag aaatatctat
       61 cctatcttct agaatgtctt ccaaacgaga aaactctcgt aaacaaaaat gttttagagg
      121 cctatttacc gtggactaaa gttgtacaag aaaaatgcaa ataagaaatc tccagattag
      181 gaactatccg tgagttctct agtctggaga tttttcaata gacttcgtta ttggacggtt
      241 accaagttac tcaaagtaca gatttgaagc tgcagataag actgacgaaa tcactttaat
      301 actaaatgaa aatcaaaaag caaactaaga agctagcctc aggctgtact tgagtacggt
      361 aaggcgacgc tgacgtgatt tgaagagatt ttcgaagagt ataaaacact gttttgaggt
      421 ggtggataaa tcggctgggt aaaaactcaa tctcaggaga aaatgaagta aatctcccca
      481 caactataga aaaagatttg attctgctcc tcacacaata aaatcttttt cttttattaa
      541 aaacgaatcg tttcacgtgt tttctcatat gaggtaacaa agcgattggt tacaccaggc
      601 tctgccactt ccaatgcttg agaaatctta tcaaatgaag cgtgataatc aaattctttt
      661 tcaaaaatat ctaaagcttc gttaaatgct tcttgaatgc gttcatcaaa tgagcgatag
      721 cggttagaat attgcaagag ttgctctgtc aaagttgcat attgtacaat attataagtt
      781 tccgtttcta aagcttccat atcattcgtt gcaatttcaa gaactcgggt aacagattca
      841 atgttaatca ttttttgttc taactcaacc attaaatcct cggtattatt gcttgccgta
      901 aagaataact tcaagaaagt ttgtggaata cctggcagat tgcgtttttc catgtatcgc
      961 ttgatagtat ggagacgatt gacataaaca ttggcctttt gacgtgcatt aatatcatct
     1021 ttctcaattt gtgtcaggcg ctcactaact gaaatttgct catcttcaat atcttttagt
     1081 tgagtttgta aatcctcaag attttcttca agaactgaat aagcttgggg tggttcttct
     1141 tgatttgaag ttacctcaac aatagctgcc tcaaaactct ctaattctgt ctgaatacga
     1201 cgaacatggc ttgcagctgt ctcaggaagt aaataggtct tgttcaaacg tgcaatatct
     1261 tctcccaata aagtattatt ctctttcata tgttgaagat aagttggaag agttgcaagt
     1321 agattttcca ctactttctg agcagcaatt tctcgagtaa aaatatcata caaggcattg
     1381 atttcctctt gtgcctgtcc attctcatat tcggcattat ccaattccaa ctgacgaata
     1441 ttctcttggt ttttcttgaa tgcttcataa agcaagtgga aacgcgcttc aatatccgtt
     1501 tcaacaaaat gataattagc atcaattagt ttacgataac cggcttccaa atcctgtaat
     1561 tgatctggca attctgtaga aagcgtcgta accaaggctg gaacacgatc cacaatatga
     1621 cttaaggcca aaatgtgatt ttctgtatta tccaaaatca ctgcggcttc cacagggtca
     1681 cccgatgaat tcaaggttac aaattgtgaa aattcagatt ggatattttc taattgtttt
     1741 tcaatttcat ccaaggcttg accatactgt tctgaatttt cagcaactct atgctgaagt
     1801 tcctcaaata aatccaaagc atgaagaaca cgaccactat ttttagattc ttgcttctct
     1861 aagtctgcca aagcattgcg aattgccgca atatcttctt caatcaaagt aatttgactc
     1921 tcaatttggt caatttgatg actggccttg agaaaacgaa atgaatggtt ataaccttct
     1981 gcttcaaaga gattattttc aatatcggca aaagagttga gagataaatc gacccatttt
     2041 tgattccatt cacggaaagc cacttgactt tgtccaatca agtgcatatt ttttacagct
     2101 tctacttcat catttactgg aagattgtat agttcttctt ttctttcttc tagtgcctct
     2161 aatctcccct cgtttcgctt acgtagaaag attgccacta cataagccag aactaaaatg
     2221 actgcaattg caaccattaa ataaattagt tgtccattag acatatcaaa ctcctttttt
     2281 acttgaaaca atcgtaacga ttatatcata ttttttagac caagggaact acttctccct
     2341 attttttaga catcaagtgt actatagaca gcattttctt cgataaactc acgacgaggc
     2401 tctactcgat cccccatcaa catatcaaag attttatctg cttctgcagc atcatctaca
     2461 gaaactctag ccatcaagcg atgttcggga tccatggttg tttcccacag ctgatgatcg
     2521 tccatttcac ctagcccctt ataacgctga atagtcggtt tggtacgacc ttcactataa
     2581 cgggctaaag cttcttggag tttgatttct tgatctgcac ccggctggat atattcttta
     2641 atctcgcttc caaccttgac accatagatt ggtggttggg caatataaac ataaccagct
     2701 tctaggattg gtttcatata acgataaatc aaggttaaaa gaagggtacg aatatgggct
     2761 ccatcgacat cggcatcggt catcaaaacg agtttttggt aacgggcttt cgaaacatca
     2821 aattctgcgc caaatcctgt tcccatggct gtgaaaagac tacgaatttc ttcgttagct
     2881 agaatcttat ccatacttgc tttttcaacg ttcaaaatct taccgcgaat tggaaggata
     2941 gcctgaaact cacggttacg accagatttg gctgatccac cagctgagtc tccttcgacg
     3001 atgaagagtt ctgtttcagc agggttatta gaagaacagt ctgctagttt ccctggaagg
     3061 ttggaaattt ccaaaccaga ttttttacgt gtgacttcac gcgcacgctt ggcagccaca
     3121 cgagccttgg cagctaaaat ccctttttcc acgatacgtt tggcaatctg tggattttcc
     3181 atgaggaaat cggagaaggc ttcactgaag aggcgattgg taatcttgac cacttcgcta
     3241 tttcccaatt tggtcttggt ttgtccttca aactgtggat ttgggtgttt aactgagata
     3301 actgcagtta atccttcgcg aacatcttcc cctgttaaat tatcttcatt gtctttcagt
     3361 aacttattct tacgagcata atcattgata acacgagtca gtgccgtacg gaaaccttgt
     3421 tcatgcgttc caccttcatg ggtatgaata ttattggcga aactcatgac attttcatgg
     3481 taacctgttg tgtactgcat ggctacttca actgtaatat catccatctc accgtctgta
     3541 tagattggtg tatcaaagat tacatccttg ttctcgttga tatattcaac gtaactagca
     3601 atcccacctt cataatgata atgcttggtt tgttccaaac cttggcgctt atcagtgatg
     3661 gaaatttgaa gaccgcgatt tagaaaggcc aactcttgaa tccgtttatt taatttatca
     3721 aaatcaaaga ttgttgtttc agtgaaaatt tctgggtccg gtgtgaagtg aaccgttgtt
     3781 ccagttctat ctgtatcccc aaccacctca aggtctgcaa caacatgacc acgacggtat
     3841 tcttggtaat gaatcttacc gtttttatgg acataaacgt ctaattgagt ggaaagggca
     3901 ttaactactg acgaccccac cccgtgaaga ccacctgaaa ccttgtatcc accaccgccg
     3961 aactttcctc cagcatgaag gactgtaaag acggtctcaa cagcaggacg gcctgttttt
     4021 tcctgaatat cgactgggat accacgccca tcatccacaa cagtaatcga atcatctggc
     4081 tcaataaaaa cttgaatatg gctggcaaat cctgccaagg cctcgtcaat tgagttatca
     4141 acaatttccc agactagatg gtgaagacct tcttttgagg ttgatccaat gtacatccct
     4201 ggacgcatac gaacagcctc taagccctct aaaacttgaa tttgactggc atcataatcc
     4261 tgtgcctgca gatttttgat ttcttctgtc atcttattcc tttttcttat atgtctaata
     4321 cttgtcttaa attcacgata ctggtaaaca agtgggtatc aagtcctgca gcttgacctg
     4381 cttcgatatc aatcggccga tcaccaatga caagaccaga gctaatctga tacttttctc
     4441 ttaaataaag catggattcg ggatttggct ttctcttaaa gcctgagcta gaagtcacca
     4501 cttctgtaaa ataagctgct atagaggttt tttctaaaat ttccaaaacc tgatcatttc
     4561 gatgagagac caaaaaatga cggccacctt gatttgaaat gacttccaat aggtcagaaa
     4621 ctccttcaaa taaaatcggg tgttcaagct ctctggcttc attttccttg tacttttcta
     4681 aaaaattctc taaattggga gcgaatgtct caatcgcaaa aggagtagaa acctttaaag
     4741 cttgatagac actgtcatgg tcttgtgtga taccatacag tgccaatgtt tcaacaaatg
     4801 cagctgttga agtttcataa ttatccagta aagttccacc taaatcccag atgtaatcgt
     4861 gatatttcat gccctttatt atagcatttt tttatgaaaa aagcgatgat ttccctgagt
     4921 tttccacata aaaaacgaga gaataactcc cgttttactg atttttacca aagacatctt
     4981 gatagagcat tcctgttcgt aaactctctg cgtcccctcc tagttgctcc accaactcgt
     5041 aggcaaaggc aagggctgtt gaaggacccc gactggttgt caactgacca tctaccacta
     5101 ctgtttcctt gacgtagtga ccatcaagga tttgctcttg aacgccgtca taacaagtgt
     5161 atcgcttatt tttcaatatc tctgcttgat tgagggcaat tggtgccgca caaatggctg
     5221 ctagtttctt cccttcttgc tcgaagcttt gcaattcttg aatcaaggtc tgattatcac
     5281 gtaaatgtgc agaaccaggc atacctccag gaagaacaat catatcatag tctgataaat
     5341 ctccatcaaa gacatgatct gctcttactt ggattgcatg cgaacccgtt acttgctctt
     5401 caaaaccaac catatcacat gtgatattgg ctcgacgcaa gacatctaca actgtcaagg
     5461 cttcaatttc ttcaaagccc tgagctaaca taactgctac ttttaccatg attttctcct
     5521 tatttaattt gttttaatac aacctttttc cgtttgaatg ggacttttcc gctcttttct
     5581 tcagctaaat tagtctggta actcatcgat aaaagcaaac caacaccaat caaattactg
     5641 ataatagctg atcccccttg cgaaatgaaa ggcaagggaa tccccgtcaa aggaagtagt
     5701 ccagtcacag caccgatatt ctcaaagatg tggaagagca acatcataat caaacctgtg
     5761 gaaatataag tgtagaactg gttatttgat ttaagagtaa tcttcaacat acggtaaatc
     5821 aacatgagat agagggcaat aaccaggaca gagccaataa agccaaaatc ttctgcaata
     5881 accgtaaaaa tcatatctga ctctcgaact gggataagca gattcgaagc attaaatccc
     5941 tgaccaaata agccaccact cccaatggca atctgccctt gagcctgctg gtaagtcgtt
     6001 gtttgggcaa actcaaaggg attgagccaa gccaaaatcc gattaatttg gtaggtcggc
     6061 attccaatct ggtgaagaaa agctcgtccg tccttgctaa taaagatagc taagaaacca
     6121 gcaactcctg ttacagcagt cacaaatact gggataataa ttttccaaga aacccctgat
     6181 aataaaacga ttcctgagaa aatggctaca aaaaccaaag ccgtccccaa gtcactttga
     6241 agtgctaaaa gaactaggac tggaatggta aagagaatca tccagaaaat taacaaaaag
     6301 tccagcggaa ccgtgcgtct ccattcctta tgtttctttg taaattggac aatgacacga
     6361 gccaacatga ggatatagga tatcttcata aattctgacg gttggaatag ggtaattcca
     6421 tttattgata cccagttttt ggcacccgtt gatgcaacta agcttggatt ataaaataca
     6481 atcggcaaga tcataagtcc caagcctaaa atatatagaa agggggtcac cttccaaaga
     6541 aattctgtat taaagagcat gaccacaaaa ccaatcacaa gccccaaggc aatccaggcg
     6601 acctgctgcc ctaaaatggg cagaatatta ttgggataat catgactaac ggctatatag
     6661 atagccacca caccgatgac cagtagaaaa aatactggca agagcaaact gtaatcgact
     6721 cttgagtcga gagaacgttt catatatact aaccttatac tttcatacaa tactatttat
     6781 caaagttcat taaaaaatct atcaatagcc tcgtcaactt cggatcgaga gatggtttta
     6841 acagtcgctt cttctgctag agatgctact atttgtttgc cgtatcgttt tccgacgatt
     6901 ctcctatcca aaataagagt taaggaacgt tggtattcac gtctcatact tcttcccaaa
     6961 gcctgtttta aacgaataat ggccattggc aattgataat cataaaaggc atttttccct
     7021 tcttgattca gttcttgatt aatctttttc gtcaagggtt cttgaggatt ttggaaagga
     7081 agcctcggta caacttgaat cacaaaagga tggcttgaaa aatcaactcc ctcccagaaa
     7141 cttgctgcac caagcaagat ttgttgttca cctttttcaa agcgtttctt tagctgatga
     7201 acatccccat ttttatactg ggccaagtgg ctaactgtaa gtaaatccga tactgctaga
     7261 agcatgtctt tagcggtaaa gagaaccaaa atcggttgct ggaaagcttg aatttccact
     7321 agtaaagcag ctacctctct ggcatagact tctaaggagg tttctgttac cagagggaaa
     7381 tctttgacca taaccacttc ttgttcctgt tttccccgag attcaatctt gacaaatttg
     7441 gcttcaggat agcctaaaag gtctgccaaa gaaaccctct gactaatctc aagagtagcc
     7501 gatactccca agacttggca actctcagga agtaaagagg acagaagagt acggcctgat
     7561 tttgtagaag aaatctgaat tttcttttga ctcgtttcag ttacttcaag ccagtaatca
     7621 ccttcagctg taaaatagcg aaccagctca tcaaagcctt ctacttctaa ttctgaaaaa
     7681 tactgatgga gattgtccag agaatctaag atatttttcc tagatttacc agactgaaat
     7741 tgttctatca agtagagaca ctcaaagcga atactttcta gtatccgttg ttgaaccctg
     7801 ttttcttctc ctactaaagc cttatcaatt aaatcgataa tagattgtat atcgtaggtc
     7861 tcttgaagca gattttctag agctaacaaa atcttttgga cttcatcaat aatcagtaaa
     7921 cggtcactga caaattcagg attatcttca agtctggtca cgagataggc atgattagtc
     7981 actaaaagct tgcaagtctc tgccctttct tgactacgtt tccaaaaatc ttccgtcaca
     8041 aataagctct gggatgataa attcccatca tgacgaaggt ctgctagaaa atgttggtaa
     8101 cggtagagtt gcccgatttc atccaaatct cctgtctctg tctcagtaag ccagaccaag
     8161 acttgcattt taaagcgtct aaataagcga ttttcatcat tttcctgcaa ggaatgataa
     8221 aaggcatcca acttcagata attttgtggt ccctttaagc tatgaatatc tgtatggaac
     8281 acttccttga gacgtttacc ttcttcttcc atgatttgat tttgaagaat ctttgtcgga
     8341 acactaagaa caatttgtcg ctctttggat tgagataaag cgggtaagag atagccatag
     8401 gttttcccaa tccctgtcgg cgcttgaatc agagagacag gttcatcttt caatagcaag
     8461 acaacctctt tagcaaaact ttcttgttcc tccctcactt caaggttcaa cagagaaata
     8521 tttttagaaa agtcttgaga tagttttcgt agctccagag aagctgccgt tttcttaaaa
     8581 tacagacctt gaacttggac caagtctgga gaactcagga tagattggtt gcgataagtt
     8641 tcctcaataa ccaggtagga ctcatatagg agagcgtcag ccatttccag caagcgttcc
     8701 aagagacctt taggaagctg ggtcatcttt tcccgtaaaa aaagaagtaa ttctgctgta
     8761 gcttgggcat ctgaaagggc tgtgtgtgcg tgtttaagag gaattcctaa ttctcgacac
     8821 aaaatcggca agctatattt ttccagttca gggaaaaaga cctgggccaa ttcgaccgta
     8881 tcaacacgag ggtttcttag ctcatagcct tcaaaaaata aattttccgc caagagatta
     8941 gcatcaaact gaacattatg ggctacaaaa atcccatcct ccaccaagtc aaatattttt
     9001 ctggcaactt gcgaaaaatc aggtgcttgc gccagacgtt ggtctgtcaa tcctgtcagt
     9061 tctttgatat gagcatccaa gggttcatgt ggattgacat ccgtcgtata gtgatcgacg
     9121 atttctccgt cctcaatcac gacaattccc acttggataa ttttagcctt actacctgtg
     9181 ctagttgcct ctaaatccac cacaacatag cgattaccaa tcgttttcat tataaaaaat
     9241 tataccaaaa aaagggctat ttggcacctg caaacatagg ataattttca aactcaagaa
     9301 cactactttt cttaaaaatc ccatcgaata gagcattcta gcctgctgat ttttgtaaaa
     9361 tagtgaagaa atacgaaaaa ttgagagaag aaatgttttc atcttccttc tctcaacgaa
     9421 tcatgtattt tatttaacca tgtcaggatc gtagtcataa aatcctgtat caaggaaacg
     9481 gtttttaggg tgaagtttac gaacttcttc atccagcaag aaggcttgat catggctaaa
     9541 gttgccctct tgaatcaagt tacgcgcttg gataaagagt tttgcaatct caacaaagtt
     9601 ctgaccagga gtgtagagcc cttctagttt ccagcgagta aagccatgct ccaccaattc
     9661 tgttaatttg atcatcaaat caaggtcatt gttggcaaag atatgggtcc catgattatc
     9721 ttcaaaaatg gaatagtggc tctctggatc acttggctca gccaagaaga ggtcacgttt
     9781 atgcgtcttt tcatcatcga tatgtgtaaa gttatagtag ttttgcaaga gtggacgttt
     9841 agaatgatgg atgacgctag caccgtaaac caaaacttca gcaggaattt ccaaaatctc
     9901 tggcattttg aaaagttcag ctgatggaat ttcacgcgcc aaaacagcct cagatgcacc
     9961 agccttttgt ccccagaagt taatctgacg actgctagtt accatggttg aagcatcgta
    10021 gatggtctta aatgaataac catcgcggtt aactacgtaa aagacgcctg catccccaat
    10081 cgtaatatag tctgtcttga tttcttccaa gaagtctaag aaaggcttga tacggtccat
    10141 catatcttgg tgcatgagag cattgaccgc aacgagcaat tccttaccag catcatgaac
    10201 caacttagcg atttcacgta attggtcata actaaaggtc gttggcagac gaaggccaaa
    10261 atctttctca ccgacataga tacggtctac gccagcttcg agtagttgtt caacttgttc
    10321 aatactttca gcagttgctg taatgacaat cttttccata agaaaaatta taccacattt
    10381 ctccaaaatc agccatgctt tgaaaatgaa aagggacttt attctttttg taacctttct
    10441 gtaataattc tctgccgaaa aaatgataaa ataggtatgt actgttaagg agagaatcat
    10501 gcccgtaaga aaattacaat cctatgaggt agactatcaa gaagaattaa accagcagct
    10561 tcctcattac caagcttata cacctgaagc gcaatctgat gccaatctca aggaaatcct
    10621 attttttatt aatatcgctg ttttttgtat ctgtattgct atctttagtt ttatcttttt
    10681 agcattaaaa ttatcaactg ctcttgcctt tgccgcagca atcggattca gcttacttgt
    10741 tttaaaagtt caacggtcta ttatcaaacg aaaacgtaga agataaatcc aaaatatcgc
    10801 cccaattgga gcgatatttt tattttttct ttttagatgg tgtctgaatg gcaatcttca
    10861 cttcaaagat tgttcccttg ggtttattat ctttgacagt aacagttcct tttagagcat
    10921 ctacaatttg cttggctagg gataatccta aaccaaaacc acctttttgc cgggttctag
    10981 ccttgtctac tcgataaaaa cggtcaaaaa ttttcttttt atcttctgtc gaaataccga
    11041 ttccattatc agaaacaagt aaataaagat tgcgatcggt cgccgagata agaaaatcaa
    11101 tttcaccatc ctcctcagta tacttgacgg cattatcgaa aagaatggtc atcagttgtt
    11161 tcagaagaag ctgatctgtg acaattgttc gatggatacg attttcaaaa cggaagacac
    11221 gattattttc cgaagcaatc atctcatagt ttgtgaaagt tgtattaaaa aagctagttg
    11281 gaacttctgc aagctccggc ttaatcccat catctctccg agctaagttc agcaagcttg
    11341 tcgttaaaaa acgcatattt cggacttctt ccaaactcga tgcaatgctt tcgctcacat
    11401 ccataatggt agcttctggc ttacgaaaaa gggtctctaa gcgattttgc aaaactgcga
    11461 gtggagttcg taactcatga ctggcatttt ccacaaaaga ctgttgcttc tgcatactct
    11521 caagcaaggg cctaacactg accctagcta gatagagact ggcaagtaaa gacaaaatcc
    11581 agaaactagc catcacgacc acaatcaatt gctcatgctt ttgactagcc tgctccaact
    11641 gactggtatt aatcaagaca gcagcatact tgatattggt tgaaaccgaa ctaatattgg
    11701 tctccatcaa aatcacacga tagatttctt cctgcccata gctattaaaa acctgaatct
    11761 ggtagatatg tcctagttct ttcttttcta acttaatctt atccaagccc aaaaatcgat
    11821 ttccagaaag aagttgagta aagtctttat caaagagaat gacttccgta ttggaactga
    11881 cattaggttt tatttctact ttactagcgt ccgccctagc attttctaaa tctttaatct
    11941 cttctgttgc cctatttata gccagctgaa taactgcttg aggattttca ctcagtccat
    12001 gaagcttatc gtccaccgaa gtataaagac tcgaatgcat gacttgtaaa ataatcagag
    12061 tcattgtaga aaaaatcagg gtgaagacac cgaagttgcg gataaaataa ctaaagtcat
    12121 ccgcatacca tgttttttta agtttactga acatctttta aaagataccc aacactacgc
    12181 aaggtttgca aattctctgc aaaagtggtt ccctttaatt tcttacggac ttttgaaaca
    12241 tagacttcga caaccgaaat cgttgtatca ctatcaaatc cccatagacg gtcaaaaatc
    12301 tgcgtcttag gcaaaatcac attttgattt tgaaggaaat aaactagtaa atcgaactct
    12361 ttccccagca attcgacagg agtatcttca actttaacgg tattggttga taaattaacc
    12421 acgatattcc cataagtcaa ggtgttttca ttaaacttcc ctgaacgttt gagaagggcc
    12481 tgaatccgca ttttaagttc ttctaggtag aaaggtttgg tcagataatc atccgctccc
    12541 agttcaaatc catgtccctt gtcatccaaa ctttccttgg cagtcataat cagaactggt
    12601 gtcgtaattc ccttttcacg caattctttt aagacttgga aaccattttt ttctggcaac
    12661 atcaaatcca gcaaaatcaa gtcatagaca ccactctcag cttcgtagag accttcttct
    12721 ccatcaaata cctgcataac atccgcaaaa tcgtctaaaa agtcaaatac tgaatttgac
    12781 agacctaggt catcctcaac caataagatt tttatcatga gaaactcctc cttattaaaa
    12841 ctattatacc aaatttgcct taaaaaaaac tcaactctct gcattttaca tgagatagct
    12901 gagttttctt tttattttag gcttatttat gcatttccgt attgaagaac aactgcttcg
    12961 actgcagctt tttcacggct aatcaagtca acacgtgctg caatttcctt gattcccata
    13021 ccgatgttac ggctaagagc aaggtcagaa agttgcggct caaagaactc cttgtattcc
    13081 gccaagcgtt gctgagtctt aaatacatga gcaggaagga taacaaagct atcaaagctc
    13141 atatctcctc caagggctgc cttaatccaa gcccagtttt cacgcgccca agaccaagct
    13201 gttttctgag ttgcttgatg agctaggaat tggtaatacc aagcagacaa gtcctgtggt
    13261 ttgaccacaa atttgtcctt ccaagaagta atcaagtttt ggatattatc cgcatctgta
    13321 ctgtatgcaa gagctgctgc caactggcgt ttaaagacag catctgttgc gtgagtataa
    13381 gtatcaagat aaagtgctaa caagtcttta gtctcatgat gtttcatctc attaatcaga
    13441 acttgtgaac gaatagctgc tgggagtcct gcaagattct ccttgtgtgt tgcgaagatt
    13501 tggctagcga cttgactagc ttctgcatca tttgagcgaa tcatcatcga aacagccagc
    13561 tgacgaacca attcatcctc atctgattct ccgtctttag cttcaaaacc aagacggtca
    13621 tagttatgac gagccaattt agcaaccagt cctttgaagg ctgtttcagc atccgttcct
    13681 tcatcaataa agcgctcaag ggctgaaatc acttgagaaa cagctgaaac caccagataa
    13741 gactcttcct tagcaagttt atcaagaact ggaagcaagt ctgcataaga aatgtgccct
    13801 gcctcagcca acaaacgacg ttcttgaaca atttgcagtt tgcttgtgtt atcaagtgtc
    13861 tctagctcag caagaacagc ttctaacaag tctccttgat agtcggtaat atagtgggca
    13921 gtattttcag tgttgagacg aagagctcct tcattttcag caagaagagc tgcgtagcca
    13981 gggatttcga tactttcagt ttcgagtgta tcaggcaagc ctttccagtt gctattgagg
    14041 ggcaccaccc agagacggtt cttgtcttcg ttctcaccga tgaagaattg tttttgtgaa
    14101 atcttcaaga catcattttc aactttaaca gtaagaactg ggtaaccagg ctgttccaac
    14161 caagaatcca tgaaggctgc gacatcacgt cctgacgctt gaccaagggc atcccaaagg
    14221 tcactaccaa tggtgttgct gtattggtgt ttttcaaagt aggcgtgcaa acctttagca
    14281 aaatcagcat ctcctagcca acggcgaagc atgtgcatga gacggcttcc tttggcatag
    14341 acgatagcgc cgtcaaagag tgtattgatt tcatctggat gtttaacttc gacgtggaca
    14401 gactgaacgc catcagtagc gtcacgttca agagcaagag gtactccacc tgtttggaaa
    14461 tcttcaaaga tattccagct tggttcgatg gtatccacac agacgtattc catcatatta
    14521 gcaaaacttt cattgagcca aaggtcatcc caccatttca tagtcacgag gttcccaaac
    14581 cattggtgag ccaattcatg ggccacaaca agggcaactt gttgacggct agcaaatgta
    14641 gagttctcat cgacaaccaa gtaaacttca cggtaggtca caagacccca gttttccata
    14701 gcaccagctg agaagtcagg aagggcgatg tggagagatt gaggaattgg gtacttaact
    14761 ccatagtaat cttcgtaaaa ctcgatagag cgaacagcga tatccagtga gaaatcaaga
    14821 tttgaaagtg gatgtgcttt ggttgagtag acacctacca gggtaccatt tttagtttta
    14881 gcggtcaccc cttgcaaatc accagcaaca aaggccaaca agtaagaaga catgcgaggt
    14941 gttgtctcaa acttccagat acctgtttcc ttacggtttt caacatcgat ttctggcatg
    15001 tttgacaagg ccaattcacc ttctgcttgg tcaaagcgaa gagagagatc aaaagttgct
    15061 ttggcttcag gctcatccac acatgggaaa gcttcgcgcg caaaatggct ctcgaactga
    15121 gtagacaagc cctccttctt gactccatca actgtataat aagaagggta aatccctgtc
    15181 atgttgtctg taattttacc agaaaaggca agaaccaatt caacttgacc agcctcagcc
    15241 aattcgatat gaagggcttc attgtcatgg tcaactgtaa atggacgagc ttgacctgca
    15301 acttctacag aggtgatttc caagtctttt tggtggaggg agatgcggtc actctgtgct
    15361 tgaccagtga tggtcacttt cccagaaaaa gtcttggtct cacgactcaa atctaaaaat
    15421 aaatcataat gttcaggaac aaattgctta ataaaatgtt caactgcttg catagttttc
    15481 tcctattcta agtttaagag ctgctgctct tcttcaaaca aacttattat atcatatttt
    15541 gcttgagaaa aaaggattgg acagcgattt ccaaaacttt cttccttcta atagtctaca
    15601 gtgggtagac cttgcgaaat tcttctaaaa caaccttgct ttcaggtgta aaagtcagcc
    15661 ctacttcacc caaacagtct gtgaaaaagt cctcatgagc ctggcgccaa taggcaagtg
    15721 atttgtctcc ctcaccttcc ttaaaggcat gttgcgcaga gacttgattg aagagttcaa
    15781 cagaaacctt tgtaatttcg acaatgcaga cagactgatt ttgactatct aaaatgacat
    15841 cgaaggtccc tacttgggga agtggttcgt cttctagtac atagaggtca taggctgatg
    15901 ctgttgctgt cttttctcct ttaaacacca aatccgctaa aaggtctggt tcaactccaa
    15961 aagcccaagc atcgatttca tctccgatca aaggattgat ttgcttgtat ttattccaca
    16021 tttcttgcgg tatcatgggt actcctttgt aattttttac tttcttcttt tatgtgttta
    16081 agatgatctg gatggtcaat ctctaaatca aaaatctctg gaatagaact gtagtggata
    16141 atgcacttga tacccaactg attcattttt tgtatgaaag aagtattcag atagcctgct
    16201 acagcaaaat taatcttgtt ctttcttgct ttatcctgca tatctcttag catatctaac
    16261 attattggac tttccatatc atgccattga ctgtttctca tagtcgcaaa aacaaaggaa
    16321 gtcaaatcat tcattccaac tacaatcttt gaaatgcccg tttccagtat actagataag
    16381 tcaaaatacg ctgacggtaa ttcaatcatc gttccgactt tcccagtaaa gccatactga
    16441 cgcaatactg taatagcttg ttttaattgg tcggcatcat tgacagaagg aaagataaga
    16501 gatagattgg ggttggtttg ataaacttct gtaacgacat gtgcttcagc ctgaaattca
    16561 tccaaacacg ccagtaaacg tctggttcct ctatagccaa acaagggatg cccttcgtca
    16621 aaaaactctc tagtccccac taaacaattg gcttctgtat tcgttaattc agaaaaacga
    16681 taccaaactt cttcatctga gtacagggag cagatagtct ctagataatc ttttacaaat
    16741 tgctgacaac ttgctaatat gatgttttga ttaagctctc tcaacaaata ttccccacga
    16801 atcatgccga cgtggtgaaa tagttgagga taaatttttt caagaatttt ttcgccacta
    16861 agggcaagtt gatttctcat agccattcac ctcgtcttaa aagatacaat atcatatata
    16921 attatatcaa aatttcctct agttcaaaag cttcataagg ttcagataac tcatatccta
    16981 aaaattctgc tacttttttg gaagcctcat tatgagcatc ccaaagtgga aacatatctc
    17041 tatttaaact ctctagaatc attgcagcac caagcttttt agcaaatcca tttccttgtt
    17101 cgtttggtct agttgcaact tccacttcaa ctgctttacg gtaaactaac cctgaggaaa
    17161 tcccagcaat cagttcatta tttttaagaa tcacaaagcc aaatccacct tttaaaacaa
    17221 aatcctgata ggactcaaaa tccccctgta aatcctgtga ccattcttcc gtagaaaagc
    17281 agttataaat atgattatca ataggcacaa tattgtaacc ttcctctaaa tgagtaacta
    17341 gattatttaa aaattcaact tgaaaatttg ccttatcttt aaaagaatag cgagtaaaag
    17401 aatttagccc cacttttcga tgcagaaaat cttgccaatt agtattttct gaaataataa
    17461 tcttataatc taaaccatat tttctaacaa aatcttccca aaatctggaa tccaactccc
    17521 ctgctaggta tagaaaattc ccaacatcat aaaagcttgt tgtcctatca ttgtttcggt
    17581 agacagttcc aatttgagat ttaagaccat agagaaccat atttttcttc catgttttaa
    17641 atagttccat tatccctcta cttcaccttc caattcatgt aagaagtctt gtccagttct
    17701 ggcaatccta ataattcaga cttaaccttc aagactaatg gcgatgcatt ttcttctgta
    17761 atctcttgaa tatccatcca aatatatcca agtgaatcat tcgcaccatc agacacagct
    17821 tccgaaatcg taacttgagg tgcactctca ttcatttcaa catcatacaa ggctatgaca
    17881 tggtgaacca taaaattttt taactcttcc ctgacgaaaa catcgtagat tcgaggatta
    17941 gagtagcttc taacagtaaa tcccgtctct tccataactt ctctagtcag cgtttccgtc
    18001 agtccttcac caagttgctg actgcctcca ggtagatcat accgatgttg ataagggcct
    18061 ctcgtttttt caatgcaaag taactttcca ttttcaaagc aaacacagta gaccccaaag
    18121 tgatttttga tttccatcca actcctccta cttcaaagac cagccaccat ctattgtcag
    18181 aatttgtccc tgcatggcag atgcctttcc actggccaaa aagagactga cttctgccac
    18241 ttcctctggt tcaatccagc gcttgattgg tgtttcacta gccacccagt cagctaagcc
    18301 acctgtctca aaatccgcag cggtcatagc tgtcttgact gctcctggag cgataccaaa
    18361 gacctgaatc ccagcttcag catagtctag agccaactgc ttggtgaagc cagccaaggc
    18421 atgcttggat gaagtatagg cgtgaccacc tccacctgct aggctagaag caatggaaca
    18481 catattgatg atgattccct ttttattttc cagcatttgt gtcaaataat accgagtcaa
    18541 ctctactgga ataatgtagt tgatttcaaa aatctcttga atgtcctgcg ccgtttgttc
    18601 caacagtggt ttgtaatcat ccaaaactcc ggcagtatta cacaaaacat ccacctgagg
    18661 gcaccagtca aaaataggtt ccaagtccaa ggtcaaatct ctctgtaaaa agtgaaaatc
    18721 accctctaag agtggctttt caccttggtc aactccataa acttgatagc ccttctctaa
    18781 aaagaggcga gcttgagcca atccgatccc tgaactcact cctgtaatga gtacacgttt
    18841 agtcatgcac ttctacccaa tccgttgcca aaacatcaca aactgtcggg ctccacatgg
    18901 aaaaaccttc tccttctcca gaaacgttga ttaggaaata aggtgtcatt tcaagtgcaa
    18961 gcccattttg ctcgatggta tcaaagagtt ggacatagtt ttccgcacct ccccaaccag
    19021 ttcgtacata ttttctctta gcctttaacc caggcaggat ctcttcaaat gtcatgtttt
    19081 tctcctttaa ttctacattc ttcatttaat tatagcaaaa aaccacttta tacggctttt
    19141 tgactgtgag ttattcaaac ctgctactac ttacggcaaa ttattccctg cagcaagata
    19201 aatttcatac cattcttttc ttgttaagct aaagtttgcc gctcggctaa cttctctcaa
    19261 gtgcttagga tttgttgtac ctacgactgc ctacattttt gctggataac gcaatatcca
    19321 agaaatggca atagttgaag aggttactcc atatttaata gctaaacgat caagtacttg
    19381 atttaaagct tgaaatttct catttccaac aaagttccct ttaaaatacc cgaattgcaa
    19441 gacagaccat gcttgaatga ccacatcgtg taatttgcaa tattcaaaaa tgctgccatc
    19501 tcgcatagct gcttgactat cttccatatt aacatgaaaa gctgattcaa atcctggagt
    19561 aaaagccgca ctcaattgta gctgattaac agctaacggc tgcttgacat cttttttaag
    19621 caactccatc atcataggat tttgattaga aactccaaaa tctcgaactt taccttgttt
    19681 ataaaggaga tcaaaggctt ctgctacttg gtcagattcc atcaaagcat ctggtcgatg
    19741 aaggagcaag ctatctagat gatcaatctt caatctttgc aaaataccgt ctactgattt
    19801 tataatatag tccttagaaa aatcaaaata ggtaaattct tcaatgcgaa tgccacattt
    19861 ggactgaatc cacatctttt ctcttaaatc tggacgattt tttaggacaa gacctaacag
    19921 ttcttcacaa cgaccacgac cataaatatc agccaagtcg aaggcattga ttccaacaga
    19981 aagtgctgtt tctacaagct cttcaacttc ttttacagac ttatctttta ttctcatcat
    20041 tccgagaaca atttctgata attctttgtc atcttgacca agagttatgt atctcatcaa
    20101 atttttctcc tttaatttct aacattcttc ccttcattat aacaaaaaac cgctttgcaa
    20161 cggctttttg actatacttc actccatttt atcttcttaa acccacggaa caagacaaag
    20221 attccaataa agaggacagc taaaggaata acttttgtaa ggaaaacatt tgaaattccc
    20281 atctactcat aataacggag cagagaaccc accacaagat gggcaataat catactgaca
    20341 aatggacgaa agaccgcttc tttccaattc caaataccga taactagcga aatcgtaaag
    20401 acagacaaac tatcccaggg agccggaata taaaaggctc cttcttgtat gaagcttgcc
    20461 attcctacat atcctaaaac aactagaaga actatagtcc caacaacaat gtaagtgcca
    20521 attttcattt taggagaatc ttggactaaa cttcttcgta aaattgtggc cacaagtcca
    20581 aatccaatca gaaaaataag aagttgccct aaaaatgtga gcaaattgac tgttaagaga
    20641 ggacctttag aaaaatcact tagtagttga taataacgta ataccgccag gacaagaatt
    20701 ggcgtcaaaa gggactcttt gatagaactg cgaggtgctc ccttgagaat ctctttcatt
    20761 atttttttag gattcttacc tagataatcc tctgcactca tgccatctcg ttctgcttct
    20821 gagaaatcta gcatcatcaa atagatctgc tctctgagat agtcttcatc atagagaaat
    20881 ccagcaagat taaaactttc ccacaactcc tcaaaatact tttgattctc ctcagaaaac
    20941 tcatgtagca aagcgcttgt ttcttcgtaa tacttcattt tcttcatggt ttaaccccca
    21001 ttcttaatcc cttctacttt ttgactcaaa tcgtcccatt gttgccaaaa gactgagaca
    21061 cgctcttctc cttctttcat taatgaaaaa tacttccgat ctggaccatc tggcgacggg
    21121 cgcatgtcgc ctcttatcca ttgatttttt tctaactttt gcaacaaagg ataaatagtt
    21181 cctggaacga tagtatcaaa tccagcctct cgcaaagtct gaaccaactc ataaccatac
    21241 cgctcttttt gaccaatcat atccaagaca caaccttcaa gaacaccttt taatagctga
    21301 gtttctttca tcacttctcc cttctaatct attttgtaat acctactagt aacttcacct
    21361 atagtatatc acttctacac tagtttgtaa agcataatag ttaatactct tcgaaaatct
    21421 cttcaaacca cgtcagcgtc gccctaccgt atgtatggtt
//
LOCUS       DAYYYC010000032        21347 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.032, whole genome shotgun sequence.
ACCESSION   DAYYYC010000032 DAYYYC010000000
VERSION     DAYYYC010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.032"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            234..1235
                     /locus_tag="ACHBV5_001348"
     CDS             234..1235
                     /locus_tag="ACHBV5_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM9967134.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            1386..2303
                     /locus_tag="ACHBV5_001349"
     CDS             1386..2303
                     /locus_tag="ACHBV5_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9967135.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            2314..3204
                     /locus_tag="ACHBV5_001350"
     CDS             2314..3204
                     /locus_tag="ACHBV5_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM9967136.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            3233..4849
                     /locus_tag="ACHBV5_001351"
     CDS             3233..4849
                     /locus_tag="ACHBV5_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM9967137.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            4859..6178
                     /locus_tag="ACHBV5_001352"
     CDS             4859..6178
                     /locus_tag="ACHBV5_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFM9967138.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(6388..6460)
                     /locus_tag="ACHBV5_001353"
     tRNA            complement(6388..6460)
                     /locus_tag="ACHBV5_001353"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6425..6427),aa:Lys,seq:ctt)
     gene            complement(6725..7996)
                     /locus_tag="ACHBV5_001354"
     CDS             complement(6725..7996)
                     /locus_tag="ACHBV5_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFM9967139.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            8266..8466
                     /locus_tag="ACHBV5_001355"
     CDS             8266..8466
                     /locus_tag="ACHBV5_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967140.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            8670..8849
                     /locus_tag="ACHBV5_001356"
     CDS             8670..8849
                     /locus_tag="ACHBV5_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967141.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            8986..9165
                     /locus_tag="ACHBV5_001357"
     CDS             8986..9165
                     /locus_tag="ACHBV5_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HFM9967142.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            9202..9654
                     /locus_tag="ACHBV5_001358"
     CDS             9202..9654
                     /locus_tag="ACHBV5_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFM9967143.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            9945..10415
                     /locus_tag="ACHBV5_001359"
     CDS             9945..10415
                     /locus_tag="ACHBV5_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFM9967144.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            10434..11522
                     /locus_tag="ACHBV5_001360"
     CDS             10434..11522
                     /locus_tag="ACHBV5_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HFM9967145.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            11503..11637
                     /locus_tag="ACHBV5_001361"
                     /pseudo
     CDS             11503..11637
                     /locus_tag="ACHBV5_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
     gene            11771..12805
                     /locus_tag="ACHBV5_001362"
     CDS             11771..12805
                     /locus_tag="ACHBV5_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFM9967146.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            12867..15050
                     /locus_tag="ACHBV5_001363"
     CDS             12867..15050
                     /locus_tag="ACHBV5_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HFM9967147.1"
                     /translation="MGPITIPKKTIITLEHLKYLHFSLEETKTYWEKNNIIDGILISI
                     YYNRIVAKSNRINGYFNVGGGNPFPNDTIVGAKFNDEKTKHIVTHYISRDALNKTITV
                     LSKIIEVFEEHFDRAITCEMFSDSSTFASINFSEYGISKSKFQQYLRDSCFIENFGVE
                     HTTVSDIQNSIVTFYDVHTDIFRLLNKLNIDISEANIMNQTTVLLDEKNIELLLSKAP
                     YLVSMIVEDFSKLSVDDFSLDNNDLKINLPSPMNEPVVGVIDTLFDKRVYFNEWVEYH
                     DFVSPDISKDSQDYKHGTAVTSLIVDGANLNPNLDDGCGNFRVRHFGVSLQSGFNSFT
                     IIKQIKEIVSQNADIKVWNLSLGSNDEIRENFISAEGALLDEIQFENDVIFIIAGTNA
                     SVINGKRKRIGAPADSLNSIIVNSVDFNNQSVSYSREGIVLSFFVKPDVSYYGGGNGD
                     FINVCEPLGLGRVAGTSFAAPFIARKMAYLIHIMGLSREEAKALLIDAAIPWNDKKTF
                     TDLSLIGNGIVPIKMDDILSTPDDEIKFIVSDISRAYDTYNYDFPVPISSESYPYVAK
                     ATMCYFPNCSRKQGVDYTNTEMQLTFGRLKSDGIKSINKDNQHAEDTPGYVRENAARN
                     IFRKWDNVKHIGESFTSRKRAKAILNPSNPQWGMSIKTIERLKSGDGQGVRFGVVVTL
                     KELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSLNEEIEFE"
     gene            15101..16117
                     /locus_tag="ACHBV5_001364"
     CDS             15101..16117
                     /locus_tag="ACHBV5_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbiH family protein"
                     /protein_id="HFM9967148.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYRDFYEFQNKVYISRTENEEKYSN
                     FIYESLFSDKVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEVVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDDMRTSLPVINQPAIDKKYNENPHQDDIVNIVTLNYT
                     HVIDKLYNGSAKSFRNQLRANLYNFYIEPPIHAHGTVDVCTVLGVSDEIQISNSLEEQ
                     KESLIKSLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDRYIWSQIAERSISGSV
                     PVIIYHYVPHFDPGNPIRAKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIFD
                     LIER"
     gene            16132..17082
                     /gene="prmA"
                     /locus_tag="ACHBV5_001365"
     CDS             16132..17082
                     /gene="prmA"
                     /locus_tag="ACHBV5_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFM9967149.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTVLA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEMIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            17084..17827
                     /locus_tag="ACHBV5_001366"
     CDS             17084..17827
                     /locus_tag="ACHBV5_001366"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFM9967150.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            17838..19634
                     /gene="pepF"
                     /locus_tag="ACHBV5_001367"
     CDS             17838..19634
                     /gene="pepF"
                     /locus_tag="ACHBV5_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFM9967151.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            19881..20435
                     /locus_tag="ACHBV5_001368"
     CDS             19881..20435
                     /locus_tag="ACHBV5_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HFM9967152.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLSNQGL
                     HYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPDFPKNRVHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            20546..21214
                     /locus_tag="ACHBV5_001369"
     CDS             20546..21214
                     /locus_tag="ACHBV5_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFM9967153.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         6727 a         3551 c         4613 g         6456 t
ORIGIN      
        1 gatttatagc cctctaaaac tcttgctttt tttgtagaag atacgaaaaa agccataaaa
       61 ccaaggcttt tcctgtttta tgtagatgtt tacacatgaa aattgaagta ttttcaaaag
      121 ctaattggag tgattttatt catgatggga taaatgatct ggccaaaaat gattgagaaa
      181 tagttgctta aaaagcattt gcatgatact atatattgaa aggaggtgat aatatggtag
      241 aacaaagaaa atcaattacc atgaaagatg ttgctttaga agcaggagtt agtgttggaa
      301 ctgtttcacg tgtaattaat aaagaaaaag gcattaaaga agtaactttg aaaaaagtgg
      361 aacaagcgat taaaactttg aattacattc cagattacta tgctagagga atgaaaaaaa
      421 atcgaacaga aacgattgca atcattgtac caagtatctg gcatcccttc ttttcagaat
      481 ttgctatgca tgtggaaaat gaagtctata agagaaataa caaattactc ttatgttcta
      541 taaatggtac aaatagagag caagactatc tggagatgtt gcgtcataat aaagttgatg
      601 gagtggttgc cattacctat agtccaattg aacattactt gacgtcagga attccctttg
      661 ttagtattga ccgcacatac tcagatattg ccattccttg tgtttcatca gataatgatg
      721 caggtggaag agaagcagct aaacaattaa ttagtaaagg atgtcagcat ttagcctttg
      781 tgggcggaca taatacaacc attaatgaaa ccaaacgtcg tagaatttca tttgaaaagt
      841 atgtccaaga gcataaaata cctcttagta tttttgattt ggatgagaca gttactgact
      901 attatggaaa gctagagagt ttcttggaag aaaattcttc tatagatgga atttttacaa
      961 tcaacgattt tacagctttg gatgtgattg aaatactaga aaaaaatggc aaacgtattc
     1021 ctcatgatgt ccaaattatt ggatacgatg gaattaaaat ggctggagat agagattatc
     1081 tactttcaac tattgaacaa ccattggaag aaatggcaaa agaagcggtt cgtattttgt
     1141 ttgatataat tgatggaaag actgttaatt tgcagacaat cctaccagta aaatttgttg
     1201 aaggaaaaac aacaaaaaat gaaaataagt cttgacagaa agcgctatca atgatagaat
     1261 gaattcagat aaaaagattt atttttaaaa caaaaatgaa acgtttcaaa aaaagaaata
     1321 aaaagacagc gccaagcgct atcttttata gaaaaaatga aacgtttcaa aaaaaggagg
     1381 ttgctatgaa tagcaaagcg aagcaagttt ctctttggga aagaatcaag aaacaaaaac
     1441 tcttgttatt gatgactgtc cccggtttag ttttaacctt tatctttaaa tacatcccta
     1501 tgtatggggt tttaatcgca tttaaagatt acaatccttt aaaaggaatt ttagggagtg
     1561 attggattgg tttttctgag tttacaaaat tcatatcctc tcccaacttt ggtatcttgt
     1621 tagccaacac attaaaatta agtatctatg gtttattgct tggcttttta ccaccaatca
     1681 ttcttgcgat tatgctcaat caactcttga gtgaaaaagt caaaaaacga attcagctca
     1741 ttttatacgc accaaacttt atctcagtcg ttgttattgt cggtatgatt ttcctcttct
     1801 tttcagtggg aggaccaatc aacaattttc tttctatgtt tggaatgaag gctgacttct
     1861 tgacaaatcc agacttcttt agacccttat acatctttag tggtatctgg caaggaatgg
     1921 gctgggcttc aacgctctac acggcaacat tggtaaatgt agatccagcc ttagtagaag
     1981 cagctcgact ggatggagcc aatatcttcc aacgaatctg gcacattgat attccagctc
     2041 ttaagcctat tatggttatc caatttgttt tagctgcagg tggaattatg aatgtcggat
     2101 atgaaaaagc attcttgatg cagacatcgt taaatttgcc aacttctgaa attatctcga
     2161 catatgtcta taaagttggt cttgtatcag gagactattc ttactcaaca gcggttggtt
     2221 tgtttaatgc agtgattaac gtagtattgc ttgttgcagt taaccaaatc gttaaacgca
     2281 tgaataatgg tgaaggaatt taaggaggaa agtatgaaaa attcgattat ggatacaaaa
     2341 tttgatagac gtatcttact cttaaataaa atcattattg tctttatcgt tttgatgact
     2401 ttgcttcctt tactttatat cgtcgtagca tcctttatgg atcctaaggt tctggttagt
     2461 agagggatta gctttaatcc agccgattgg actgtagaag gttaccagcg tgtattcagt
     2521 gaccaatcta ttctaagagg ttttatcaat tctctactat actcttttgg atttgcagct
     2581 ttaacagtat tgctatctgt gtttacagct tatcctcttt ctaagaaaga cttggttgga
     2641 cgtcgttgga ttaactactt cttgattgtg actatgttct ttggtggtgg tttagtccca
     2701 acttacttgc tcgtaaaaga attgggaatg ctcaatactc catgggctat cattgttcca
     2761 ggtgctgtca atgtttggaa tattattctt gctagggcct atttccaagg attgcctgaa
     2821 gaattagttg aagctgctgt cattgatgga gcgaatgact tgcagatttt ctttaaaatc
     2881 atgcttcctc ttgcaaaacc aattatgttt gttctcttcc tctatgcttt tgtaggacag
     2941 tggaactcat actttgatgc aatgatttat atcaaggatc caaacttgga accattgcaa
     3001 cttgtacttc gtaaaattct cattcagagc caaccaggtc aagacatgat tggagcacaa
     3061 gcggctatga atgaaatgaa acgtttagct gaattgatta aatacgcaac tattgtcatt
     3121 tccagcttgc cattgattgt tatgtatcca ttcttccaaa aatactttga taaaggaatt
     3181 atggctggtt cacttaaagg ataaaaaaag aaaaaataaa aggagttttc tcatgaaatt
     3241 caaaacattc tcaaaatcag cagttttgtt gacagctagt ttagcagtac ttgcagcctg
     3301 tggctcaaaa aatacagctt caagtccaga ttataagttg gaaggtgtaa cattcccgct
     3361 tcaagaaaag aaaacattga agtttatgac agccagttca ccgttatctc ctaaagaccc
     3421 aaatgaaaag ttaattttgc aacgtttgga gaaggaaact ggcgttcata ttgactggac
     3481 caactaccaa tccgactttg cagaaaaacg taacttggat atttctagtg gtgatttacc
     3541 agatgctatc cacaacgacg gagcttcaga tgtggacttg atgaactggg ctaaaaaagg
     3601 tgttattatt ccagttgaag atttgattga taaatacatg ccaaatctta agaaaatttt
     3661 ggatgagaaa ccagagtaca aggccttgat gacagcacct gatgggcaca tttactcatt
     3721 cccatggatt gaagagcttg gagatggtaa agagtctatt cacagcgtca acgatatggc
     3781 ttggattaac aaagattggc ttaagaaact tggtcttgaa atgccaaaaa ctactgatga
     3841 tttgattaaa gtcctagaag ctttcaaaaa cggggatcca aatggaaatg gagaggctga
     3901 tgaaattcca ttttcattta ttagtggtaa cggaaacgaa gattttaaat tcctatttgc
     3961 tgcatttggt ataggggata acgatgatca tttagtagta ggaaatgatg gcaaagttga
     4021 cttcacagca gataacgata actataaaga aggtgtcaaa tttatccgtc aattgcaaga
     4081 aaaaggcctg attgataaag aagctttcga acatgattgg aatagttaca ttgctaaagg
     4141 tcatgatcag aaatttggtg tttactttac atgggataag aataatgtta ctggaagtaa
     4201 cgaaagttat gatgttttac cagtacttgc tggaccaagt ggtcaaaaac acgtagctcg
     4261 tacaaacggt atgggatttg cacgtgacaa gatggttatt accagtgtaa acaaaaacct
     4321 agaattgaca gctaaatgga ttgatgcaca atacgctcca ctccaatctg tgcaaaataa
     4381 ctggggaact tacggagatg acaaacaaca aaacatcttt gaattggatc aagcgtcaaa
     4441 tagtctaaaa cacttaccac taaacggaac tgcaccagca gaacttcgtc aaaagactga
     4501 agtaggagga ccactagcta tcctagattc atactatggt aaagtaacaa ccatgcctga
     4561 tgatgccaaa tggcgtttgg atcttatcaa agaatattat gttccttaca tgagcaatga
     4621 caataactat ccaagagtct ttatgacaca ggaagatttg gacaaaattg cccatatcga
     4681 agcagatatg aatgactata tctaccgtaa acgtgctgaa tggattgtaa atggcaatat
     4741 tgatactgag tgggatgatt acaagaaaga acttgaaaaa tacggacttt ctgattacct
     4801 cgctattaaa caaaaatact acgaccaata ccaagcaaac aaaaactaga ggttgattat
     4861 gggagataag aaatacacag tagaaaaagc caatcgtttt atagcagaaa ataaacatct
     4921 cgttaatact caatataagc ctgaagaaca tttttcagct gagattggtt ggatcaatga
     4981 tccaaatgga tttgtctatt ttcgtggaga ataccatctc ttttatcaat tctatccata
     5041 tgatagtgtt tgggggccta tgcactgggg acatgctaaa agtaaggact tggtgacttg
     5101 ggagcacttg ccagtggcac ttgctcctga ccaagattat gaccgaaatg gttgtttctc
     5161 aggctctgcc attgtcaagg atgatcgcct ctggctcatg tacactggac atatcgaaga
     5221 agaaaccggt gtccgccaag tgcaaaatat ggcattttca gatgacggga ttcactttga
     5281 aaagatttcc caaaatccag ttgcaactgg atcagacttg ccagatgagt tgattgctgc
     5341 tgatttccgt gatccaaaac tctttgaaaa agatggacgc tattactccg tagtagctgc
     5401 caaacataag gataatgtgg gctgtatcgt tctactaggg tccgataacc tagtagaatg
     5461 gcagttcgaa tccatctttt taaaaggggt agaacaccaa ggctttatgt gggaatgccc
     5521 agattacttc gagttagatg ggaaagattg ccttattatg tcacccatgc gttatcagcg
     5581 tgagggagac tcatatcata acatcaactc atcgcttttg ttcacgggta aggtagattg
     5641 gggagaaaaa tgttttatcc cagaatcagt tcaagaaatt gatcatggcc aagacttcta
     5701 tgcgcctcaa acattgttgg acgatcaaaa tcgtcgtatc ctgattgctt ggatgcagac
     5761 atgggggcgt acccttccaa cccatgacca agaacacaaa tgggcatgtg ccatgacttt
     5821 acctagaatt ttaagattgg aagatggcaa actaagacaa ttccctgtta aaaaaggcca
     5881 atatcaaatc caaatagata aagattgtca ttaccactta ggaaatgata tagattatct
     5941 tgaatttggt tatgatagta atgcgcagca agtttacatt gatcgtagcc atcttattca
     6001 aaaaattcta ggtgaagaag aacaggacac tagtcgacgg tatgtagata ttgaagctaa
     6061 agaattggaa gttgttctag ataaaaattc catcgagatt tttgtcaatc aaggtgaagc
     6121 aagcttgact gcaacttatt acttaacggt gccagctgag ctatcacgaa ttgattaaaa
     6181 attaagttat ttctcctaaa gaaaaagttc tctttctaaa atagtggaaa gaggactttt
     6241 tgtgttttgg gtatataagc ttagtttatg gtatttgtaa aattggtgtt ggattatgat
     6301 ttaagctagt tttctaaaga atttgaaaaa aattttattt aagcaaaaaa aacccttggt
     6361 tccaaggctt ttcctgttgt atttatatgc cccctacagg gatcgaacct gtgacccacg
     6421 gattaagagt ccgctgctct gccagctgag ctaaggaggc aaagaaaaaa gctgtattgg
     6481 tgccgaaact tcacggtttg tattgaaccc gcgcaattaa gcaggtgggc aactcgctct
     6541 aactgaagct gtttccgtgt gagacggcct acatgctgtt agaagacttt tgtttcccta
     6601 ataatacaaa aaatagtcgg tcaacactta agtgtgaagt cgtacaccac agcgtttcta
     6661 tacttatatg ataccacttt ttcaaaaaaa atcaagagga aagtgcaatt ttttgaaaag
     6721 gatttcagat ttttcgcaaa cggtcgatag cttcctttct ttgagccaaa gcccgttcat
     6781 atttaccagt atcttctgct tggaaatagt gatgattacg aattttttct ggcagatagt
     6841 cttgcttgac ccaatttcca ggatagttgt gtggatagag atagtcttgg gcattcccca
     6901 gttccttgct tccactgtag tgcccatcac gtaggtgtcg cggaataggc aagtgccctg
     6961 atgttttgag gtcagcaagt gccttatcca tagctacata ggctgagttg gattttggag
     7021 aaagggccaa atcaatcacg acattggcaa tgagaatgcg ggcttctggg aacccaatct
     7081 tctgggcagc atccagagca gtcacggtat gaatctgggc ctcaggattg gctaagccga
     7141 tatcttcata ggcgataaca gtcaagcgac gagcgagact aggcagatcc ccagcctcaa
     7201 tcaagcgggc agtatagtgg agactggcat ccacatctga gccacgaata gacttttgca
     7261 gggcagatag aacatcatag tgaccgtctc catccttgtc catagtgatg tagcttctct
     7321 gaagactatt ttccatgatg tctaaggtga tgtggcgaat gccctcgtca ttctcagggg
     7381 tagagagaac agctaagtcc agtgagttaa aggcagagcg aaggtctccg tttgtagagg
     7441 ttgcgatgaa atccagcgca tcctcatcta gttctattgg aaaatcaaaa ccacgttcag
     7501 ggttacttag agctatctgc agggcctctt tgacgtcttg gttagacaga ggttccaact
     7561 cgaaaatttg aactcggcta cgaatggcag gagtgacaga gaagaaagga ttttcagtcg
     7621 ttgctccaat catgatgacc agtccacttt ccaagagagg caagaggaag tcttgcttgg
     7681 tcttatctag tcgatgaatt tcgtctagca ataggacgag accaccagaa aatttagctt
     7741 cttccgagat ttcttgcagt cgctttttac tatcaactgt cgcattgaaa gttcgaaagg
     7801 catacttggt cgttccagcg atggcagagg caatactggt tttgccgatt ccaggagggc
     7861 catatagaat catggaggac aggcggttgg cttccaccat gcggcggatg atttttccag
     7921 gtccgaccag atgctcctga ccgatgacct ggtcgatggt tttagggcgc atgcgaagcg
     7981 cgagattgtc tggcatagca gtcctttcta gcgtggattt gagtagaatg actcatctac
     8041 tatatcttac tatgtccatt ctagcctatt agttgtgata tttcaatggt tttgtaataa
     8101 tcagggagtg agatagaatc ttttttacta tttaatttaa tgaggagagg tatcagcatg
     8161 agagatttga ttttccttaa agctcaaaat aggatagttg agcctaaaga agtggaagtg
     8221 ctgacttgag aaataatatt gctgaatgtc attgtatgaa ctataatgaa aagagaggtg
     8281 ataagtaatg gaaatgatgg accaagtcag gaaattttga tttttacaaa acaaattcgt
     8341 cattggattc ttagtgatca agttatttca gggaaaagaa aacttttctt ccgggaagat
     8401 actccaaaag agattttaga tttgtacgaa aacattaaat ctaaacttga ttttgcttac
     8461 caataagttt attctaataa tgggttgaaa aaatatgaaa aatagaataa ttgatgtttt
     8521 tgaagtagta aatcgcatcc ttgtaataac tgttgaaaat cctgatttcg aagacttgag
     8581 agttaatcat actcaatgaa aatcaaagag caaactagga aactagccgc aggctgtact
     8641 tgagtacggt aaggcgacgt tgacgtggtt tgaatttgat tttcgaagag tatcagtttg
     8701 taaaaattgg agataaaaaa tatagagtac gcagtgttcc tatgattcat tcaactccgc
     8761 ctcaatctgt cttagatcga gatactttta caattgacta tacagatgat gaattgctcg
     8821 ataaagaagc agtttttact actcattaga aaaataggtc tgaataaatt ggcttccctt
     8881 agaaccacat ctaggggctt ttatgtataa tagaataata agtatcactc ctttacaata
     8941 cgtgtaacac gtgttataat ggtgttgtca ggaggtaaaa gcgctatgcc tatgacacaa
     9001 aaagagatgg ttaaactcct tacggcccat ggttggataa agactagagg cggtaaaggc
     9061 tcccatatta aaatggagaa gcaaggggaa agacttatca caatccctca tggtgagctg
     9121 aataagtaca ctgaaagagg gataagaaag caagctgggt tgtaaaattc agcccctgtt
     9181 ttttgatatg gaggtagtga aatgttagtt acgtatccag ctttatttta ttatgacgac
     9241 acagacggaa cagaagcgac ttattttgtc catttcccag attttgaata ctcagctaca
     9301 caaggagagg ggatttctga ggctttggct atggggtcgg agtggctagg gataactgtt
     9361 gcagatttga tagagagtga tggagagtta cctcagccat cagatatcaa tagcttgtct
     9421 ttaattgata atgatccttt taaagatgat gaagatttcg tgtcaaccta tgaccttgat
     9481 aaatctttta tttctatggt atctgttgat gtatcagaat acctaggaag tcaggaaccc
     9541 ataaaaaaga ctttgaccat accaaaatgg gcagataagt tgggacgaga aatgggactt
     9601 aacttttctc agactttgac agacgctatt gcagataaga aagttcaagc ctaagattaa
     9661 gcgtggtatc gtggtaatag tcaataaaaa agcacgtcca cttgtgctag ttactcgcct
     9721 attgatttta tagatttatt agccctttcg cgggcttttt atattgattt ttatgagaaa
     9781 tgaagaaatc agacttttaa gaaaatcact gataccaagg gtttaaatga ggtaatatgg
     9841 tataattagg acataaaata attttgtggt aagatggtag tatctatttt agcatatttc
     9901 cgagcaatcg gggcgattaa agagtcgcat agaaagagga caaaatggca acatacggat
     9961 ttttagatgt tttagaggaa gagttggaca agaactttcc ctttgacttt gagattagct
    10021 gggacaaacg caaccatgcg gtagaagtga gttttctatt ggaagcgcaa aatgctgcag
    10081 gtgtggagat ggtggatgaa gacggagagg ttttatcaga tgacattctt tttgaggaag
    10141 cggtcctttt ctacaatcct gccaagtcaa cagtcaatga ggaagactat ttgactgtta
    10201 ttccttacct gcctaaaaaa ggattttccc gtgaattttt agcttatttt gcgcttttcc
    10261 ttaaagatac tgctgaggtt gggctagatg tcctcatgga ctttttggaa gacccagaag
    10321 cagaggaatt tgtcatggaa tggaaccaag aagtctttga agaaggaaaa gttggcttgg
    10381 aagagggaga attttatcct tatccaagat actaggagtt ggttggaggt gttatgaaga
    10441 aaattgggac ttatttggtt tatgtgctag cttttgtctt tattatgcta gcttttgctt
    10501 gtggaacaat cgcatttgca gagttggggt attccgcagt tttagccttt acttttggtt
    10561 atgccttcgc tcttctaagc atgtatttaa tctttattct tcatgagctg ggtcatgctt
    10621 tttgtggcta cttgacaggc tatcggctgg tggcttttgg attaggacat tttattttga
    10681 ccaaaaagtc aggcaggttt catcttagta gaacagccat tctgaaaaat gttggtgctc
    10741 aatacattgg tttaaaagag gatgaaagcg atcaaagaat catcctgatg ctttcaggag
    10801 gcttgatggt tcatctcggc ttgatattat tggcgatagt gtttggattt ttgacaagaa
    10861 gctggtattt tgcagggact tggatttttc ttaatttatc tttcttccta aataacattt
    10921 tgccagtcga catcaccgat ggagcaaaaa tttgggaatt actacaacac cctgaaaata
    10981 ccaaatacgc ctacctggta ttgagacatt ctgctcaaac tttgctggct cctcaagaat
    11041 atgatttgaa agactttgtt caagcagttc ctgaggatgc acgagggagt tttgcggatg
    11101 gtgtattagg tatgcaaggt gaagtttcca ttttggaagg gaaggaagaa gtagctaaac
    11161 agcagtttca agcattactt gagaggacaa ctactccgat gatgcagaca gttgcccaac
    11221 tatccctgct tcatatcgcc ttgttggaag gagattttga gcaagcggag caatatgcta
    11281 gtattcgaca ggtcaaatcg tttctgtctc tcaaactgtc caatcttcaa gtgatacaag
    11341 cttggtatca atttaaggta aagaaagatg tagatcgaac tcgtaaggct ctcaagattg
    11401 ctagacagaa aatggatagt agtcgaatgt tgagggacga gaaacgctat tatgaaaact
    11461 tgttagcaga gctggaaaag gaaatgttag aaggaactga agatggaact agaaatttct
    11521 gatttcccag gctgtaagat tgctttgttt tgtggggata agctcttgac tatcttacgt
    11581 gatgataagg caagtattcc ctgggccaat atgtgggaac tgccaggtgg tggaaagagt
    11641 gtcagggaaa atctgatata gttttgtatt aaaagaatat cctttcaagg ttattctttt
    11701 ttaattttgt cccaaaataa ttgactttgt cccgaaaata tagtattatt tgtgtaagga
    11761 ggaatgaatc atgaaaaaat cagatgttct tgatttaata aagtatcatt atgagggcag
    11821 agagacagaa tttagaaatc aatccatagc aattgctcgg aacttcaata aacatggtga
    11881 tacacaaata gcacaatata ttatggggtt aatgtctcaa agtgatagat tcatgccaca
    11941 aatagaaaat cctagtgagt atttgactcc tgctaaacta gatattggtc ctctcccatt
    12001 gcctctttca attatgaatg atttaaaagg aataataaac gctgtcaatc atcatattgg
    12061 aataaataaa tttttatttg tgggatctcc aggtactgga aaaactgaaa gtgtaaagca
    12121 ggtggctaga cttattggca aggaattact tgtagtagat ttcagtcact tagtagatag
    12181 taagctaggg caaacagtca aaaacttagc aactcttttt aatgaaatca ataatcttcc
    12241 tttcaagcaa aattatatca tcctatttga tgaaattgat tccatagtgt tggatagggt
    12301 taatcagaat gatttaagag aaatgggacg agtgacttct gcctttttaa aggagttgga
    12361 taggctgtca ccagaaattg tattaattgc aacaacaaat ctttttgaaa atcttgataa
    12421 agcagttacg agaagattcg atgccataat tgactttgac cgttatactg atgaagataa
    12481 agtagaagta gctactatta ttttaaatga gttattaaag caatttaaga atgtagctag
    12541 agatttaaaa ttatttaaaa aaattatcaa tagtgccaat gtaataccga atcctggtga
    12601 tttgagaaac tcaataagaa cgtcattggc atttagtgac ccatcagatc cgcatgatta
    12661 ccaaaaacgc ctgctaagaa gtttgcataa tggtagaaat ttatctattt ctaaattatc
    12721 gaagctaggt tttactgtta gagaaattga gattttgaca ggtatttcta agagtagtgt
    12781 atcacgagag ttaagcgagg attaaaatga atacattatt gacattacga ggtaaaagtt
    12841 ttacacaaaa atcaagaaat aatggtatgg gaccaataac tatacccaaa aaaacaataa
    12901 ttacattgga acatttgaag tatcttcatt tttcattaga agagacgaaa acatattggg
    12961 agaaaaataa cattatcgat ggtattttga tcagtattta ctataatcga attgttgcca
    13021 aaagtaaccg tattaatggc tatttcaatg taggaggagg gaatccattc cctaatgata
    13081 ctattgtggg agcaaaattc aatgatgaga agacaaaaca tattgttact cattatattt
    13141 ctagagatgc tcttaataaa acaataaccg ttttaagtaa gataattgaa gtttttgagg
    13201 aacattttga tagagcgata acatgtgaga tgttttctga ttcatcaacg tttgcttcta
    13261 taaatttttc ggagtatggt atttcaaaaa gcaaatttca acagtatttg agagattctt
    13321 gctttattga gaattttgga gttgagcaca ctactgtttc tgatattcaa aattctatcg
    13381 tgacatttta tgatgtccat acagacattt ttagattact gaataaatta aatattgata
    13441 tttcagaagc taatatcatg aatcagacca cggtcttgct tgatgaaaaa aatattgaat
    13501 tgctactatc aaaagcgccc tatcttgtct ccatgattgt ggaagatttt tctaagttat
    13561 ctgtagatga tttttcttta gataataatg atttaaaaat aaatcttcca tctccaatga
    13621 acgaaccagt tgttggcgtt attgatacct tatttgacaa aagagtttac tttaatgagt
    13681 gggtagaata tcatgatttt gtctcacctg atattagcaa agatagccaa gattacaagc
    13741 atgggacagc tgtgacttct ttaatcgttg atggagccaa tttgaaccct aatctggatg
    13801 atggttgtgg aaattttaga gtgaggcatt ttggtgtgtc actacaaagt ggatttaatt
    13861 catttacaat cataaaacag ataaaagaga ttgtttctca gaatgctgat attaaggttt
    13921 ggaatctttc tttagggtcc aatgatgaaa taagagaaaa ttttatctct gcagagggag
    13981 cattattaga cgaaattcaa tttgagaatg atgtaatttt tatcatagct gggacaaatg
    14041 cttcagtaat aaatgggaaa cgcaaaagaa taggtgctcc tgctgattca cttaattcta
    14101 taatagtaaa ttctgttgat tttaataatc aatcagtgtc atattcacga gagggtattg
    14161 ttttatcatt ctttgttaaa ccagatgtgt catattatgg aggaggaaat ggtgacttta
    14221 taaatgtttg tgaacctcta ggattaggtc gtgtagctgg aacaagtttt gcggcacctt
    14281 ttattgcaag gaaaatggcc tatctcattc atattatggg acttagccga gaagaagcga
    14341 aggctttgct aattgatgca gcaataccct ggaatgataa gaaaacattc actgatttat
    14401 ctttgatagg aaatggtatt gttccaataa aaatggatga tattttatct acacctgatg
    14461 atgaaattaa atttattgtg tcagatatct ctagggctta tgatacctat aattatgatt
    14521 ttccagtacc tatttctagt gagagttatc catatgtagc taaagcaaca atgtgttatt
    14581 tccctaactg ctcaagaaaa caaggggttg attatacaaa tactgagatg cagcttactt
    14641 ttggtaggtt aaagtcagac ggtatcaaat cgataaataa agacaaccag catgccgaag
    14701 ataccccagg atatgtgaga gaaaacgctg ctagaaatat atttaggaaa tgggataatg
    14761 tcaagcatat tggagagtcg tttacttctc gaaagagagc taaagcaatt ttaaatccat
    14821 ctaatcctca gtgggggatg agtattaaaa caatcgaacg tttgaaaagc ggtgatggac
    14881 aaggagtacg ttttggtgta gtagttacat taaaagaatt aaatggggtt aatcgtattg
    14941 aagattttat tcagcaagct gaattacgcg gttggctagt taatagattg caagtagaag
    15001 ctcaagtaga cctctttaat agtttaaatg aagaaattga atttgaatag tggatatttt
    15061 atccttattt tagatcttag gaacacaaga gggcaaagat atgaatatta cttatatagt
    15121 tggaaatggt ttggatttgc aatatggttt gaaaacaaga tatagggatt tctacgaatt
    15181 ccaaaataag gtttatataa gtaggacaga gaacgaggaa aaatattcaa atttcattta
    15241 tgagtctcta ttttctgata aagtaaatga ttatgaaaat tggtcagatt ttgaattgtc
    15301 aattggtaaa ttgacaaaag ataacgacct catctcctca agtatagaaa taaaggagaa
    15361 atttatagat gattttagtg aagtagttga tgatttaaga gaatatctac gcatacaaca
    15421 agaaaaaaat cttgagaaag gtaatgcaat tgactttata agcactctag atgatatgag
    15481 gacctctctc cctgtaatta atcaacctgc tatcgataaa aaatacaatg agaatccaca
    15541 tcaggacgac attgtaaata tagtaacact taattataca catgtaatcg ataaattata
    15601 taatgggtca gcaaaatcat tcaggaatca attacgagct aatctttata atttttatat
    15661 tgagccacca attcatgcac atgggacggt ggatgtctgc acggttttag gggttagtga
    15721 tgaaatacaa atttcaaata gtttagaaga acaaaaggaa tccctaataa aaagtttagt
    15781 tttaaaaaac tatagagaaa atatggatgt aaagaatagt gatattataa aaaattctga
    15841 catcattatt ctctatgggg tttctttggg agaaactgat aggtatatct ggagtcagat
    15901 tgctgaacga tcaatcagcg gttctgttcc tgtcataatt taccactatg tacctcattt
    15961 tgatccgggg aatcccatta gagcaaaacg cctatataga aatgtagaag ataaattcat
    16021 acagaatagt ggtatagact tagagttaga gaaaaaatta agagacaacc ttattgtcgt
    16081 tattggtaag actatttttg atctaataga gaggtaattt taaaaaacaa aatggaaaca
    16141 tggcaagagt taaaagttac agtgaagcgt gagggagagg agttggtttc caatctcttg
    16201 attgagctgg gagcgcaagg tgttgcgatt gaagacagta tggactatgt gggaaatgtt
    16261 gaccgctttg gcgagatttt cccagaggtg gagcagcaag aagaaatcgt agtgacagcc
    16321 tactaccctg acacggtgga tgtgacagtg gttgaggcgg acttgcaggc tcgcttagca
    16381 gaattgacgg attttatgga tttgggagag ttaaaaatag gtacgactgt cttggctgag
    16441 gaagactggg cagataactg gaagaaatac tatgagccag ctcgtatcac tcatgatttg
    16501 accatcgttc cctcttggac agactatgag gcgactgcgg gggaaatgat tatcaagctg
    16561 gatcctggca tggcttttgg tactggaacc cacccaacta ccaagatgag cctttttgcc
    16621 ttggaacagg ttcttcgtgg tggcgaaacg gtgctagatg tggggactgg ttcaggggtt
    16681 ctctctattg ccagctcgct tctgggggct aaagaaattt tcgcctatga cctagatgat
    16741 gtagcagttc gtgttgctca ggaaaatatt gaacttaacc ctggaatgga aaatatccac
    16801 gttgctgctg gagacttgct taagggtgtt gagattgagg cagatgtgat tgtagctaat
    16861 atcttggcgg atattctcat tcatctgaca gacgatgcct atcgtttggt caaggatgaa
    16921 ggctacctga tcatgagtgg cattatcaag gacaagtggg acatggtgcg cgagtcggct
    16981 gagtcagctg gatttttcct tgaaacccac atggttcaag gggaatggaa tgcctgtgtc
    17041 tttaagaaaa ccaaggatat ttctggtgtg attggaggct agcatgcagc agtattttgt
    17101 aaaaggcagt gctatctctc ctgtcactat cgaggacaag gaaaccagta agcatatgtt
    17161 tcaggttatg cgcttgaaag aagaggatga ggttacctta gtctttgatg atggcatcaa
    17221 gcgcttggcg cgcgtgctgg atatggaaaa tcgtcagttt gagttggtcc aagaattaaa
    17281 tgacaatgtg gaactaccag ttcaagtgac catcgcatct ggatttccca agggagacaa
    17341 gctggagttc atcgctcaaa aagtaaccga actgggtgct agccaaatct gggcctttcc
    17401 tgcagactgg tcagttgcca agtgggatgg caagaaattg ggtaaaaaag ttgaaaaact
    17461 agaaaaaatt gcccttggag cagccgagca aagcaagcgt aatattgtac caagtattaa
    17521 acttttcgag aaaaaagcag attttctaac tcagctggac cagtttgact ctatcatagt
    17581 agcctatgaa gaatcagcta aagaaggaga agccgctgcg cttctgcaag cagtcactgg
    17641 tcttgaaaca ggagccaaac tgctctttat ctttggtcca gaaggcggtc tctcacctgc
    17701 agaaatcgaa agttttgaag ctaagggagc cgttttggta ggcctaggtc ctcgtatttt
    17761 gcgagcagaa acagcaccgc tttacgcctt atcagccctt agtgttttag tagaattaga
    17821 gaaataagag gaagaaaatg gaacaaaaac accgttcaga atttccagag aaggaacttt
    17881 gggatttaac agctctatac caagaccgtg aggatttctt gcgtgcaatc gagaaagctc
    17941 gcgaagacat caaccagttt agccgtgatt acaagggcaa tcttcacact tttgaggatt
    18001 tcgagaaggc ctttgcggaa ttggaacaga tctacattca gatgagccat attggcaact
    18061 atgcttttat gcctcagacg acggactata gcaatgacga atttgcaaat attgctcaag
    18121 ctgggatgga atttgaaaca gatgccagcg tagccttgac cttctttgac gatgccttgg
    18181 tggtagcaga cgaggaagtc ttggaccgtt tgggtgaatt gcctcacttg acggcagcta
    18241 ttcgtcaggc caaaatcaaa aaagcccact atctaggggc tgatgtggag aaggccttga
    18301 ccaatctcgg tgaagttttc tatagtccgc aggacattta tactaagatg cgagctgggg
    18361 attttgaaat ggctgacttt gaagcccatg gcaagaccta taaaaacagc tttgtcacct
    18421 atgagaattt ctaccaaaat cacgaggatg ctgaggttcg tgagaaatcc ttccgttcct
    18481 tctcagaggg acttcgtaag caccaaaata cggctgcagc agcctatctg gctcaggtca
    18541 agtctgaaaa actcttggct gatatgaagg gatacgactc tgtctttgat tatcttctag
    18601 ctgaacaaga agtggaccgt gtcatgtttg accgccagat tgacctcatc atgaaggact
    18661 ttgcaccagt cgctcagaga tacctcaagc atgttgccaa ggtaaatggt cttgaaaaga
    18721 tgacctttgc agactggaaa ttggacttgg acagcgccct caatcctgaa gtgactattg
    18781 acgatgccta tgatttggtc atgaagtcgg tagaaccttt ggggcaagaa tattgtcagg
    18841 aagttgctcg ttaccaagaa gagcgctggg tggactttgc tgctaacagt ggcaaggatt
    18901 ccggtggtta tgcggcggac ccatatcgcg tacaccctta tgtactcatg agctggacag
    18961 gccgtttgag cgatgtctat accttgattc atgaaatcgg gcattctggt caattcatct
    19021 tttcagacaa tcaccaaagc tatttcaacg cccacatgtc gacctattat gttgaagcac
    19081 cgtcgacctt caatgaattg ctactcagtg attacttaga gaaccagtct aatgacccac
    19141 gtcaaaaacg cttcgctctg gctcatcgct tgacagacac ctacttccat aatttcatca
    19201 cccacctctt ggaagccgcc ttccagcgta aggtgtatac attgattgaa gaaggagaaa
    19261 ccttcggagc aagcaaactc aacagcatta tgaaggaagt tttgacagat ttttggggcg
    19321 atgccattga aatcgacgac gatgcagctt tgacttggat gcgccaagct cactactata
    19381 tgggcttgta tagttacact tactctgctg gtcttgtcat ctcgacagct ggttaccttc
    19441 atcttaaaaa ctcagaaact ggagctgaag actggctcaa tctcctcaaa tcaggtggta
    19501 gcaagacacc acttgagtca gccatgatta tcggtgctga tatttcaaca gacaaaccac
    19561 tccgtgatac catccaattc ttgtctgaca cagttgacca gattatcgcc tacagtgctg
    19621 agttggggga gtaaggggaa tagaaaaatt ttctagaatg atgtttatgg gcttgttaag
    19681 cgtcattcta tttgtcttag ttgtagctat tttcaaaaat gtcgttgaag gtcgtgatgt
    19741 taaatttgaa cttactgtag aactggtatt gatagttatt tacgtcattt tatatcagat
    19801 tgtatttaat tgagaattca atattgagtc atttaagact gcctttttga acagttgcta
    19861 gaaatgtaga ggtattgacc atgtatcaag atttactaag aaaaatagca gaagaaaaac
    19921 caaattataa ccaggaagaa atccagtggt tgtttgatca tttgggaaat ccttctccag
    19981 aaattcgtga tgacctttca aatcaaggct tgcactatct ttcaaaagaa aaggatacaa
    20041 caggtttctc aagtcagtat ggttgggttc acgcttttgc acatggagcc gatttactga
    20101 cagaggtggt ttgtcatcca gactttccta aaaacagagt tcatgaagta tttgatatac
    20161 ttggccaact atttaaaaga atgtcgattc gctttacaga tgatgaggat tggcgtttag
    20221 caagagtgat ctatgaacct attttacaag ggaagttgga gcaagaacaa gtagcttctt
    20281 ggataaaaac tgttgatttt ccgatagaag aaagggagga tttttacaaa ttttccaact
    20341 ttagatcctg tctggtggaa gtctatgtcc aacttgacca gagaaatagt ttacaagatg
    20401 agttgaaaga agctatccag tcttttcaat actagagatt agctaatagt tctatgattt
    20461 tcaaaaaatt tccaatcaat tttcttgaaa ccctttccta cttttgatag actagtatct
    20521 agtttttgaa aaaaggagaa agaaaatgaa aaaatttgtt gctgagttaa tcggtacgtt
    20581 catgcttgtg ttcgttggga caggagctgt tgtttttgga aatggtcttg atggccttgg
    20641 tcaccttgga atcgcctttg cctttggttt ggcaatcgtg gtggcagcct actcaatcgg
    20701 aactgtttca ggtgctcact tgaacccggc tgtttcgatt gctatgtttg taaacaaacg
    20761 tttgtcatct tcagaacttg taaactacat ccttggtcag gttgttggag ctttcatcgc
    20821 ttctggcgct gtcttcttcc tcttggctaa ctcaggtatg tcaactgcta gtcttggtga
    20881 aaatgccttg gcaaacggtg tcactgtctt tggtggtttc ttgtttgaag tcatcgcaac
    20941 tttcttgttt gtattggtta tcatgactgt gacttcagaa agcaagggca atggcgcgat
    21001 tgctggtttg gtaatcggtt tgtcattgat ggcgatgatt cttgtcggat tgaagattac
    21061 tggactttca gtaaacccag ctcgtagctt ggcaccagct gtcttggtag gcggcgcagc
    21121 ccttcaacaa gtttggattt tcatccttgc accaatcgct ggtggagttc ttgcagccct
    21181 tgttgcaaaa aatttccttg gaacagaaga ataattgaaa ctcaaaaagc cttgctcctc
    21241 atcttgagga acagggcttt ttcgtatgat actcttcgaa aatctcttca aaccacgtca
    21301 gcttcacctt gccgtaggta tggttactga cttcgtcagt tctatcc
//
LOCUS       DAYYYC010000033        21166 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.033, whole genome shotgun sequence.
ACCESSION   DAYYYC010000033 DAYYYC010000000
VERSION     DAYYYC010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21166
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.033"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..582
                     /locus_tag="ACHBV5_001370"
     CDS             <1..582
                     /locus_tag="ACHBV5_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFM9967154.1"
                     /translation="NNFDEIIYINLTDHISSSIERYKEGVIISNPLRWEISKYYKEEF
                     ELGKRALQIIKKELGIELPIDEAAFIALHFVNANLENNFQESYKITEIIMGIEKIIQD
                     FYCTEFNQDSIDYYRFITHIKLFAHRLVENTTYCDDDDEDLLALMKNKYPREYECGEQ
                     VAMFIQTEYNYLLTSSELVYLMAHIRRLTKNLD"
     gene            600..2438
                     /locus_tag="ACHBV5_001371"
     CDS             600..2438
                     /locus_tag="ACHBV5_001371"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFM9967155.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDESVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            2451..3866
                     /locus_tag="ACHBV5_001372"
     CDS             2451..3866
                     /locus_tag="ACHBV5_001372"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFM9967156.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAKLLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            4458..5504
                     /gene="pheS"
                     /locus_tag="ACHBV5_001373"
     CDS             4458..5504
                     /gene="pheS"
                     /locus_tag="ACHBV5_001373"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFM9967157.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            5504..6013
                     /locus_tag="ACHBV5_001374"
     CDS             5504..6013
                     /locus_tag="ACHBV5_001374"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9967158.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            6090..8495
                     /gene="pheT"
                     /locus_tag="ACHBV5_001375"
     CDS             6090..8495
                     /gene="pheT"
                     /locus_tag="ACHBV5_001375"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFM9967159.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNESAADALSVSIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(8563..9564)
                     /locus_tag="ACHBV5_001376"
     CDS             complement(8563..9564)
                     /locus_tag="ACHBV5_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFM9967160.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTDSGIAPVTVIVKKSYDFYTKAETFHTTRFGTIVLHSRKQDIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            9720..10209
                     /locus_tag="ACHBV5_001377"
                     /pseudo
     CDS             9720..10209
                     /locus_tag="ACHBV5_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            10293..10559
                     /locus_tag="ACHBV5_001378"
     CDS             10293..10559
                     /locus_tag="ACHBV5_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM9967161.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            10820..13069
                     /gene="metE"
                     /locus_tag="ACHBV5_001379"
     CDS             10820..13069
                     /gene="metE"
                     /locus_tag="ACHBV5_001379"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFM9967162.1"
                     /translation="MSTTIVGFPRLGEFRELKFTTEKYFRKEISEEELLSAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFTTERVGENAELRARIAG
                     LTDADYTRLPVFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            13133..13999
                     /gene="metF"
                     /locus_tag="ACHBV5_001380"
     CDS             13133..13999
                     /gene="metF"
                     /locus_tag="ACHBV5_001380"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HFM9967163.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELVPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            14684..16897
                     /gene="pnp"
                     /locus_tag="ACHBV5_001381"
     CDS             14684..16897
                     /gene="pnp"
                     /locus_tag="ACHBV5_001381"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFM9967164.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMTGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            16913..17530
                     /gene="cysE"
                     /locus_tag="ACHBV5_001382"
     CDS             16913..17530
                     /gene="cysE"
                     /locus_tag="ACHBV5_001382"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HFM9967165.1"
                     /translation="MGWWHETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            17542..18426
                     /locus_tag="ACHBV5_001383"
     CDS             17542..18426
                     /locus_tag="ACHBV5_001383"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9967166.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            18513..19856
                     /gene="cysS"
                     /locus_tag="ACHBV5_001384"
     CDS             18513..19856
                     /gene="cysS"
                     /locus_tag="ACHBV5_001384"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFM9967167.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            19849..20235
                     /locus_tag="ACHBV5_001385"
     CDS             19849..20235
                     /locus_tag="ACHBV5_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFM9967168.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            20239..21123
                     /locus_tag="ACHBV5_001386"
     CDS             20239..21123
                     /locus_tag="ACHBV5_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM9967169.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT         6441 a         3875 c         4710 g         6140 t
ORIGIN      
        1 aataattttg atgagattat ctatataaat ctaacggatc atatttcttc gagtatagaa
       61 cgttataaag aaggagttat tatttcgaat cccctacgct gggaaatctc gaaatattat
      121 aaagaagaat ttgagcttgg gaaaagggct ttacaaataa taaaaaaaga gttaggtatt
      181 gaacttccaa ttgacgaagc tgcattcata gcgctacatt ttgttaatgc taatttagaa
      241 aataattttc aagagtcgta taaaatcact gaaataatta tgggaattga gaaaatcatt
      301 caagatttct attgtactga gtttaaccaa gattctattg attattatag attcataact
      361 catataaaat tatttgccca tcgcttggtt gaaaatacaa cttattgtga cgatgatgat
      421 gaagacttgt tagcattaat gaaaaataaa tatcctagag aatatgaatg tggtgaacag
      481 gtggcaatgt ttatacaaac tgagtacaat tatttgctga cttctagtga attagtttat
      541 ttgatggctc atattcgtcg cttaacaaaa aatttagatt aatagaatag gagaatacca
      601 tgagttataa agataaggta caaaaaatcc tcgatgtaat tggaggtgaa aaaaatgtca
      661 atagagttac ccattgtgta acacgtttaa gattagaatt aaaagatgaa aatttagtca
      721 atgatgatga tgtgaagaag ataccaggtg taataggtat tatgaaaaag aatggacaat
      781 atcaaattat acttggtaat gatgtagcta attattataa agaattcgtt aaacttggca
      841 attttgaatc cgattcagtt gttcaagggc acaaagggaa tattttagaa agaatcattg
      901 agtatatcgc tggttccatg actccaatca ttccagcaat gttaggggga ggtatgctga
      961 aagtcttggt aattatttta ccaatgcttg gtatattgca atcagattct cagactattg
     1021 cttttttgac attttttggg gatgctccat attatttctt accgctgtta ttagcttatt
     1081 ctgcatcaca aaaattaaaa gtaacatcta cattagctat gtctgtagca ggtgtacttc
     1141 tccatccaaa ttttgttcaa atggtgcaat cagggaatcc tcttagttta tttggtgtac
     1201 ctgtgatacc agctagttat ggttcgtcag tcgttccaat tcttattatg gtttggttga
     1261 tgaaatatat tgaaaaaatg attgctaaat taacaccagc tgttactaag agttttttgc
     1321 aacctacgct agtattatta gtatcaagct gtattgcctt agttgtagtc gggcctattg
     1381 gagtaattgt tggtgaagga ttatcaaatc tagttgggca aatgtatgat gtagctggat
     1441 ggcttacatt agctattctt ggtgctatta tgccatttat tgttatgact ggaatgcatt
     1501 gggcttttgc acctattttt ttggcggcat ctattgctac tccagacgta ttaattcttc
     1561 cagcaatgtt agggtcaaac ttagctcaag gggctgcttc gatggctgtt gcattaaaga
     1621 gtaaaaataa taatacaaaa caaattgctt ttgcagcagg tttctcagcc ttacttgcag
     1681 ggattaccga acctgcatta tatggtgtga ctttaaaata taaaaaaccg ctttatgcag
     1741 ctatgattgg tggtggatta gcgggattat ttgcaggtct tactagtgtt aaagcgtatc
     1801 tatttgctgt cccatctttg atagcgttgc ctcaatttat ttattctgat gtaccatcaa
     1861 atattgtaaa tgctttaatt gtggcggtta tttcggttgt tattaccttt gtattagctt
     1921 atatatttgg aatcgatgaa gaagagagtt ctagcaattt agaagttaaa gctggagttt
     1981 caaataaaaa aatgatattt tctcctatat caggagaaat cattccgtta agcgatgtcc
     2041 aggataaaac attttcagat aaactaattg gagacggagt agcgattatt ccaagtgaag
     2101 gtaaggttta tgcaccattt gatgggaaaa ttacaaatat ttttccgact aagcacgcaa
     2161 ttggattgaa gagtgatgag agtgttgagt tactaattca tattggatta gatactgttg
     2221 agctaaaagg tcaaggtttt attagtcatg tagaagaagg agacagagtt ttcaaaaatc
     2281 agttgatttt tgaaatggac ttgaatttaa tcaagactaa aggctacgaa acagttacac
     2341 cagtaattgt aacgaatacc aatgattttc tagatgtatt agtattacct aataatcaga
     2401 caatcgagca ttctaaggaa ttactggtaa tattataatg gaggaaagtt atgaccattt
     2461 ttccagatga ttttctttgg ggtggagctg ttgcagctaa tcaagtagag ggagcatata
     2521 atgaagatgg taagggctta tcagttcagg atgtgttacc caaaggtgga ttaggagaag
     2581 caacagaaaa tcctacagaa gataacttaa aattgatagg tattgatttt tatcataaat
     2641 ataaggaaga tatatccttg ttttctgaaa tgggctttaa tgtttttcgt acttctattg
     2701 catggagtag aatttttcca aaaggagatg aggaagaacc taacgaagct gggttgaaat
     2761 attatgatga attgtttgat gaactacatg ctcacgggat agaaccactt gtaactcttt
     2821 cacactatga gactccatta tatttagcaa gaaaatatca tggatggatt gataggagaa
     2881 tgattcattt ttatgaaaaa tttgctcgaa cagttttaga aaggtataaa gataaagtta
     2941 aatattggct tacatttaac gaagtaaact ctgttttgga attaccgttt actagtggag
     3001 gaatagatat acctaaggag aatctttcga aacaagaatt atatcaagct atacatcatg
     3061 aattagtcgc ctcgagtttg gttacaaaaa ttgctcgtga gattaattca gagtttaagg
     3121 tggggtgtat ggtattagct atgccagctt atccaatgac tccaaatcca aaagatgtat
     3181 gggcgactca tgagtatgag aatctaaatt atctattttc agatgtgcat gttagaggtt
     3241 attatccgaa ttatgcaaaa agatatttta aggaaaatga cattaacata gagtttgcag
     3301 ctgaagatgc aaagttatta aaaaattata ccgtagattt tttatccttt agctattaca
     3361 tgagtgtgac tcaatctgct cttccaacac agtataattc aggagaaggg aatattattg
     3421 gtggcttagt aaatccttat ttagagtctt ctgagtgggg atggcaaatt gatccaattg
     3481 gactacgtat aattttaaat agatattatg accgttatca aattccatta tttatagtgg
     3541 aaaacggatt aggtgctaaa gatcaactaa taaaagatga atttaataac ttaacagtcc
     3601 aagatgatta tagaattcag tatatgaaag aacatttatt gcaagtagct gaagctctac
     3661 aagatggtgt ggaaattatg ggctatacgt cttggggatg tattgactgc gtttctatgt
     3721 ccactgcaca gctttctaag aggtacggtc tcatttatgt tgatcgaaat gatgatggaa
     3781 atggcacatt caatcgatat aagaaaatgt cctttacttg gtataaagga gtgattgaat
     3841 caaatggaga atccttattc aaatagtttg tttattgatg attagatatt atcacggtta
     3901 aggcaacatc tcattgaata tgaaataaag aggtttggaa gacatcaaat tctaaacctc
     3961 tttattttat agggggatta attaatttaa ttttgttaca gagagccgat tataaatagt
     4021 taacttagga tagattggtt atatatagta gactgaatct aaaatagtac gaaacaattg
     4081 ctaaaacatt tatagaaatt aattttactt tcccaatcga tttgttctca tcttatttca
     4141 atccgctata aagttagata agaataagct aacaagcaga agtaagatag gtcttgcaag
     4201 aatggtaaaa atctgataaa ctaagtagta attgaatagg aatctgaaag actagtagcc
     4261 caagggaagt atatcaggga ggagagccgt gactgcaagc tctctatatg aaagctgggt
     4321 gaattcactt gcgcatggat ttagaaatga aggtctgact tgtcagatga aaacggatgg
     4381 taccgcgtgt caacgctccg agtggagttt ttggcatgtg gttttctttt tatctacgag
     4441 agactgatgg aggaaatatg tcaactattg aagaacaatt aaaagcgctt cgcgaagaaa
     4501 cgctggctag cttgaagcag attactgctg gaaatgaaaa agagatgcaa gatttgcgtg
     4561 tctctgtcct tggtaaaaag ggttcgctca ctgaaatcct caaagggatg aaagatgttt
     4621 ctgctgagat gcgtccaatc atcgggaaac acgtcaatga agctcgtgat gtcttgactg
     4681 ctgcttttga agaaacagct aagctcttgg aagaaaagaa agtcgcggct caactggcta
     4741 gcgagagtat cgatgtgacg cttccaggtc gtccagttgc gactggtcac cgtcacgttt
     4801 tgacacaaac cagtgaagaa atcgaagata tcttcatcgg tatgggttat caagtcgtgg
     4861 atggttttga agtggagcaa gactactata actttgaacg tatgaacctt ccaaaagacc
     4921 acccagctcg tgatatgcag gatactttct atatcactga agaaatcttg ctccgtaccc
     4981 acacgtctcc agttcaggcg cgtgctatgg atgcccatga tttttctaaa ggtcctttga
     5041 agatgatctc gccagggcgt gtcttccgtc gcgatacgga cgatgcgacc cacagtcacc
     5101 aattccacca aatcgaaggc ttggtagttg ggaaaaatat ctctatggct gatcttcaag
     5161 gaacgcttca gttgattgtc caaaaaatgt ttggtgaaga gcgtcaaatt cgtttgcgtc
     5221 catcttactt cccattcaca gagccatctg ttgaggtgga tgtttcttgc ttcaagtgtg
     5281 gtggagaagg ctgtaatgta tgtaagaaaa caggttggat cgaaattatg ggggccggta
     5341 tggttcaccc acgtgtcctt gaaatgagtg gtatcgatgc gactgtatac tctggctttg
     5401 cctttggtct tggacaagag cgtgtagcta tgctccgtta tggaatcaac gatatccgtg
     5461 gattctacca aggagatgtc cgcttctcag aacagtttaa ataatgatta gaaaagtaga
     5521 aatggcagat gttgaggtgt tggctaaaat tgccaaacaa gcctttcgtg aaacctttgc
     5581 gtatgataat acggaagagc agttacagga atactttgaa gaggcttata gtctgaaaac
     5641 tttgtcaact gagttgggaa atcctgactc tgaaacctat ttcattatgc atgaggagga
     5701 gatagctggt tttctcaaag tcaactgggg aagtgctcaa actgagagag aattagagga
     5761 cgcttttgaa attcaacgcc tctatgtgct acaaaaattc caaggatttg gactaggtaa
     5821 gcaactgttt gaattcgcac ttgaacttgc tacaaaaaat agtttttctt gggcttggtt
     5881 aggtgtttgg gagcataata caaaagctca agcgttttat aatcgatatg gttttgaaaa
     5941 atttagccaa catcatttta tggttggtca aaaagtagat acggattggt tactgagaaa
     6001 gaaattaagg taagaagagg attcttctat tgaaatgata ggaaaggaaa agaactagag
     6061 tgacaactgt cattctggag aactaaatta tgcttgtatc ttataaatgg ttaaaagaat
     6121 tggtggacat tgatgtgcca tcacaagagt tggctgaaaa aatgtcaact acaggaatcg
     6181 aggtagaggg tgtcgaatca ccagctgctg gtctctcaaa aattgtcgtc ggtgaggtct
     6241 tgtcttgcga agatgtgcca gagactcacc tccatgtttg tcaggttaac gttggcgaag
     6301 aagaagagcg tcagatcgtt tgtggtgccc caaatgtgcg tgctgggatc aaggtcatgg
     6361 tggctcttcc aggagctcgt atcgctgata actacaaaat caaaaaagga aaaatccgtg
     6421 gtttggagtc acttggaatg atctgttcac ttggtgaatt gggaatttct gactcagttg
     6481 tgcctaagga attcgcagat ggcatccaaa tcttgccaga aaatgccgtg ccaggtgagg
     6541 aagtcttttc ttacctagac ttggatgatg aaatcatcga actttccatc acaccaaacc
     6601 gtgcagatgc cctttctatg tgtggagtgg ctcacgaagt ggcagccatc tatgacaagg
     6661 cagtcaactt taaagaattt actctaacag aaactaatga atctgcggca gatgcccttt
     6721 ctgtcagcat tgggacagac aaggcgcctt actatgcagc tcgtatcttg gacaatgtga
     6781 ctatcgcacc aagtccacaa tggttgcaaa accttctcat gaacgaaggc atccgtccca
     6841 tcaataacgt tgtagacgtg acaaactaca tcctgctcta ctttggtcaa cctatgcatg
     6901 cttttgactt ggacacattt gaagggactg acatccgtgt gcgtgaagcg cgtgctggtg
     6961 aaaagttggt gaccttggac ggtgaagaac gagacttggc tgagacagac ctcgtgatta
     7021 cagttgctga caaaccagta gcccttgccg gtgttatggg tggtcaggct acagaaattt
     7081 ctgaaaaatc tagtcgtgtt atccttgaag ctgctgtttt taatggcaaa tctatccgta
     7141 agacaagtgg tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa aaaggaatta
     7201 atgtggcaac agttaatgaa gcccttgatg cggcagctag cctgattgcg gaacttgcag
     7261 gtgcgacggt gcgtaagggt atcgtttcag cgggtgagct tgatacttca gatgtagaag
     7321 tttcttcaac tcttgctgat gttaaccgtg tcctcggaac tgagctgtct tatgctgatg
     7381 tcgaagacgt cttccgtcgt cttggctttg gtctttctgg aaatgcagac agctttacag
     7441 tcagcgtacc acgtcgtcgt tgggatatca caatcgaagc tgatctcttt gaagaaatcg
     7501 ctcgtatcta tggatatgac cgcttgccaa ccagccttcc aaaagacgat ggtacagctg
     7561 gtgaattgac tgtgacacaa aaactccgcc gtcaagttcg taccattgct gaaggagcag
     7621 gtttgacaga aatcatcacc tatactctaa caactcctga aaaagcagtt gagtttacgg
     7681 ctcaaccaag taaccttacg gaactcatgt ggccaatgac tgtggatcgt tcagtcctcc
     7741 gtcaaaatat gatttcaggt atccttgata ccgttgccta caacgtggct cgtaagaata
     7801 aaaacttggc cctttacgag attggaaaag tctttgaaca aacaggtaat ccaaaagaag
     7861 aacttccaaa tgaaatcaac agttttgcct ttgccttgac aggcttggtt gctgaaaaag
     7921 atttccaaac agcagcagtt ccagttgatt tcttctatgc taagggaatc cttgaagcgc
     7981 tctttactcg cttgggacta gaagtgacct atacagcaac agctgagatt gccagccttc
     8041 acccaggacg tacagcagtc atttcactcg gtgaccaagt tcttggtttt cttggccaag
     8101 tgcatccagt cactgccaag gcttacgata ttccagaaac gtatgtagct gagcttaacc
     8161 tttcagccat cgaaggggcg ctccaacctg ctgttccatt tgtggaaatc acgaaattcc
     8221 cagcagtcag ccgtgacgtt gcccttctcc tcaaggcaga agtaactcac caagaagttg
     8281 tagatgctat ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc tttgacgtct
     8341 tctcaggtga gaaattggga cttggtatga agtccatggc ttatagcttg accttccaaa
     8401 atccagaaga tagcttaacg gacgaagaag tcgcacgcta tatggaaaaa atccaagcat
     8461 cgctcgaaga aaaagtgaat gcagaagtgc gttaaacgat agtaggatat aaattccccc
     8521 tctagtttat gaacactaga ggggtgattt tatataaaat aattaaaatg tgatttctgt
     8581 aaaaatacat ctatgatcag agttttgaaa acttacaatg tctaaatctt taacatagta
     8641 gtggttttta ggcaataaaa tatgatctat cgttgcatta aaaagttttg gactttggct
     8701 attccaagtt cctctttcaa aaggtggcag tgcatttaat gcgtccctat gagagcttat
     8761 ttttgcaagt gctccatgac gcatagttgc attaaaatca cctgcaataa tagcctttgg
     8821 atattttgaa gccaattgat tatgaatgat gtttaagtct tgcttccaga tttccattaa
     8881 acctggcaga ggaggagcag tatgcaaagc aatgatatct ggtatatctt gttttctcga
     8941 atgtaataca attgtcccga accgtgttgt atgaaaagtt tcagcttttg tatagaaatc
     9001 gtaacttttc ttgacaatca cagtcacagg agctattcca ctgtcagtag gtggagaagt
     9061 aaaaatatca tagttggcca tagaaagtcc aacttgatga aacaatagtt tgattctctg
     9121 gttttcttgc tcacctctga tattggtagc tagttcaggg aatatagcca tatcggcgtc
     9181 aaaatggcta aaaattcgct caatatgttg tgcttctatt tgattagcga cgttccaagt
     9241 tactaatttt aaggttttag tcttatttga tgcggaagaa agggttttat ctgttccgaa
     9301 taatagtaat atgagcgata ataagagcaa aatgccagag taaaaccgta tttgtttatt
     9361 tttcttgtaa aaagataggg aaaaaaatac gaaacttaaa atggcagcca tagttgcagt
     9421 agctaagggg aaggcataaa tctgtgccaa gataggtctg gtagatagcc aaatattaag
     9481 attagaagat ggaaaaaaag aataagttat gatagggata acaaagagaa tgaccgaaag
     9541 ggcagagaga aatgttttaa tcattgtgtg agtacctcaa tttgcaatgg ttgctcggag
     9601 ctaatgtgac tttgtgactt tacttgattg atattctttt tcttgtcttc cttatagatt
     9661 aagtacaacc caagtaaaaa aagtccaatt taagattgaa atgattaaaa ggcacagaga
     9721 tgcaagacaa ttatactaca aaaggtaaac atttgacaat cgatagccgt cgcttaatcg
     9781 aaagatggaa aaaagaagga aaatcaaata gagaagttgc ctctctactt ggaaaagctc
     9841 ctcaaactat ccacactgaa atcaagcgtg ggacagtccg aaaatgtctt ggaaaagggc
     9901 gcttcaaaga ggtttattct gccgactacg ctcaacagtc ttatgaaaac aatcgcaagc
     9961 gctcggtcaa gaaatcaagc ttgaccaagg aactaaagga aaagattctc cactatacat
    10021 aaccaaaaat ttttgcctga aatgatggtg atggctaaag gggttaacgt gggaatttca
    10081 accatttact attggattca tcatggaaag ttggggttaa gcaaacagga tttgctttat
    10141 cctagaaaag gaaaatctgt taagaaacaa gttagtccca attttaaacc cgctgatcaa
    10201 tctatcgaat cataattcgc tcattttttt aaaaatacat agacgtaaaa aaaagagggt
    10261 taagtgatga agaatagtgc tattgggagt aattggaagg atgtccatct gagctcttta
    10321 gcaaggagga aatccttgaa agtgatatgc gagtggctat catgagcgag ttgattgagg
    10381 ctaggtatga acaaggaatc agtcagaaaa agctggaaga agtcagtgga ataagccagc
    10441 ctgtcatagc taggatggag acaggaaaga ctagtcctca gttggataca gtcttaaaag
    10501 tcctagccag tttaggaaag acactagcaa tcgtcccact tgaacaggga aaaagttgac
    10561 tagaatcagt tatagtcttt tctaataaca agccatagtc acttataaga attactaata
    10621 acgcgtttga gcattctaac taaaatacag ctataaaaca agctatacaa aggatttgag
    10681 acgtttgctt caagtctttt tcttttgtcc gaaacagata tatagtttca aactatatca
    10741 aaccctaatt ttttacaatt atacagacgc tttcttttct gttaagatag tttcaacaac
    10801 aaattttgga ggacacatca tgtcaactac aatcgtcggt ttccctcgtt tgggcgaatt
    10861 ccgtgaatta aaatttacaa ctgaaaaata ctttagaaaa gaaatctcag aggaagaact
    10921 tttatcagca gcaaaagact tgcgtgctaa acactggaac attgtcaaag aaaaaggcat
    10981 cactgaaatt ccatcaaatg acttttctca ctatgataac ttcctagatg cggctttcct
    11041 tttcaacgtg gtgcctgcat ccgttcaaaa cttggacttg tctgaccttg agcgctactt
    11101 cgctttggga cgtggttacc agggagaaaa aggggacgtt cgcgcccttc caatgaagaa
    11161 atggttcaac actaactacc actacatcgt tcctaaattt gaaaaagaca ctcaagtaaa
    11221 attggctggt cacaagattt tcgatgagtt ccaagaagcc aaagaacttg gattgaacac
    11281 tcgtcctgtt cttgtaggtc ccttcacttt ccttcaattg tcagactttg aagaaggcgt
    11341 gaaagcagac gacttcgtag atagcttagt ggctgcttac caagaagttt ttgctaaatt
    11401 ggctgaactt ggtgcgactc gcatccaatt ggatgaagcg gctcttgtaa aagacttgac
    11461 agctgaagaa aaagctctct tcttgaacct ttacaacaaa ctcttggctg acaaaaaagg
    11521 tcttgaagtc ttgcttcaaa cttatttcgg tgatgttcgt gacgtatacg ctgaccttgt
    11581 aaacttacca gtagatgcta tcggtcttga ctttgttgaa ggtaagaaaa ctcttgaact
    11641 cgttaaaggt ggcttcccag ctgacaagac tctctatgta ggtattgtca atggtaaaaa
    11701 catctggcgc aacaactacg aaaagagctt ggctgttctt gagcaaatcc cagctgaaaa
    11761 catcgttttg acaagctctt gctcacttct tcatgtgcca tttacaactg ctaatgaaga
    11821 atttgaacca gcactcttga accactttgc ctttgcagtt gaaaaattgg atgaaatccg
    11881 tgacttggat gctatccgca atggtcaagg ttcagaagct cttgcagcca acaaagaact
    11941 ctttacgact gagcgtgttg gtgaaaatgc tgaacttcgt gcgcgtatcg ctggcttgac
    12001 agacgcagac tacactcgtt tgccagtctt tgcagaacgt gaagctatcc aagaagaagc
    12061 tttcaaactt ccagctcttc caacaacaac gattggttca ttccctcaaa caaaagaagt
    12121 tcgtgccaaa cgtttggctt accgtaaagg tgaattgtct caaaaagagt acgatgcttt
    12181 ccttgctgaa acgattgacg aatggatcaa gtggcaagaa gatattgact ttgatgtcct
    12241 tgttcacggt gaatttgagc gtaatgacat ggttgagtac ttcggtcaaa acttgtcagg
    12301 atacctcttc tctaaaaatg gttgggtaca gtcatacggt atgcgtgggg tgaaaccacc
    12361 aatcatctgg ggtgatgtca ctcgtcttaa ccctatcact gttaaatggt ctagctatgc
    12421 acaaagccgt acaaacaaac ctgttaaagg tatgttgact ggacctgtta ccatcctcaa
    12481 ctggtcattc ccacgtgaag acatctctat caaggattca actcttcaaa tcgcccttgc
    12541 tatcaaggat gaagtgcttg accttgaagc tgctggtgtg aaaatcatcc aaattgatga
    12601 ggctgctctt cgtgaaaaat tgccactccg ccgtagcgac tggtacgaag actaccttga
    12661 ctgggctatt cctgccttcc gcttggtaca ctcaacagta gcgccagaca cacaaatcca
    12721 cactcacatg tgttactcag aatttacaga tatcatccca gctatcgata acatggatgc
    12781 agacgttatt tcctttgaag ctagccgttc aaaccttgaa atcttggacg aactcaaagc
    12841 gaaaaacttc caaacagaag tgggacctgg ggtttacgat atccactcac ctcgtgtacc
    12901 aaatgaaggc gaaatcgaca acacaatcga agccatcctt gctaaagtgc caagcaagaa
    12961 agtttggatc aaccctgact gtggtttgaa aacacgtggt atcccagaaa caaaagaaag
    13021 cttgatccgc cttgttgaag cagctaaagc tgcgcgtgag aaattgtaag attggatttc
    13081 tctccataca gtggttgttc aaaaagaaat caactagaaa aggttattac atatgtcacg
    13141 ccaaacaccg tcactctcat ttgaagtgtt ccctccaaac ccagccgtgg gtaatgataa
    13201 cattatttca gccttgcagg atatgcagga gttggttccc cattttatca gtgtaactgc
    13261 cagcaataat aaatttaata tcaaggaaac gacggttcgt ttggctgact ttatccaaaa
    13321 tgatttggcg attccgacca ttgcccactt gccagctatt tatctaacta aggacaaggt
    13381 tgctgaaact attgctgact tggacaaagt tggggtgcag aaaatcttgg ctcttcgtgg
    13441 ggatattatt ccagacgtgg aaccacaaaa ggatttccgc tatgcaaccg acttgattga
    13501 gtttatcaag gaacgagccc ctcactttga tattattgga gcttgctatc cagaagggca
    13561 tccagattcg ccaaatcaga tttcagatat tcaaaatctt aagaagaaag tggatgcagg
    13621 ctgttcgagc ctcgtaactc agctcttctt tgacaatgag cgcttctatg attttcagga
    13681 caagtgtatc ttggctggga ttgatgttcc cattcatgca ggaattatgc caattctgaa
    13741 tcgaaatcag gctctccgac tcttgaagac ttgtgagaat atccatcttc cacgcaaatt
    13801 taaagccatc ttagacaagt atgagcatga ccctgagtcg ctcagagcag caggacttgc
    13861 ctatgcagtg gaccaaatcg tggacttggt aactcaggat gttgccggtg tgcatctcta
    13921 tacgatgaat aatgctgata cagcaaaata catccatcaa gcaacccatg ccttgtttaa
    13981 tcaccagtct ctaggataat aaaagcaaac cattcttctc aggtgagggg aatggttcct
    14041 ttttaatggt aaagacctca ctttttaaga aaaatatgat aaaataaatt ctgtacgtac
    14101 ttgatacaaa gatgaaggta ttaaataata caatgcattt aaactgtaag atttaacgac
    14161 acgagtgagt caaatcgatg ttatttgacg agagagttag taaagcattt agctaatcgc
    14221 ccgatagcga ttagcgtgaa agctttagat actttagtat taaacctttc taatgatgta
    14281 tcttgaaaac tgaacttgcc tacaactctg tggaaaaaga taaatctccc taggagtagt
    14341 cgctccgtcg ttcgatttcc tatcttcctt tgagttgctt gacggcttgg tatcttgatg
    14401 acttgaattt tggtctcatt tcttaggaaa aaagataagc ttcctagcac tcgtcgagtg
    14461 tgacgtcacc ttcctatttt tctacagaaa tgttcggcaa gccgaaccgt ccaaaatatc
    14521 ttgtgtaatt gaacacggcc gaaaagctgt gtaaaaaaga taaactgtct tgtcttcatc
    14581 gaagacttcg tcagtttcct atttttactt tgcttttgac gtccttggta tcttgatctt
    14641 tgtaggcaag gcgtataatt tcatcaatcc aaaggggatt aaaatggcaa aacaagtgtt
    14701 tcaaacgact tttgcgggtc gtgagttaat tgtagaaact ggtcaggttg ctaagcaagc
    14761 aaatggctct gttgtcgtac gttacggtga gtcaactgtc ttgactgctg ccgttatgtc
    14821 taagaaaatg gcaactgggg atttcttccc actccaagtc aactacgaag aaaaaatgta
    14881 tgcggctggg aagtttcctg gtggctttat gaaacgtgaa ggacgtcctt caacagatgc
    14941 gaccttgaca gcgcgtttga ttgaccgtcc gattcgtcct atgtttgcgg aaggtttccg
    15001 taatgaagtc caagtcatca atacagtgct ttcttatgat gaaaatgcat ctgcaccaat
    15061 ggctgctatg tttggttcat ctttggcact gtctatttca gatattccat ttgacggacc
    15121 aattgctggg gtacaagtgg gatatgtaga tggccaaatc atcatcaacc caagtcaaga
    15181 acaagcagag caatctcttc ttgaattgac agtagctgga accaagcacg ctatcaacat
    15241 ggtagagtct ggtgccaaag aattgtcaga agaaatcatg ttggaagcgc ttcttaaagg
    15301 gcacgaagct gtcaaagaat tgattgcctt ccaagaagaa atcgttgctg ctgtcggtaa
    15361 agaaaaagca gaagtggaat tgcttcacgt ggatgctgaa ttgcaagctg aaatcattgc
    15421 agcctacaac agtgacctcc aaaaggcagt tcaagtagaa gagaaattgg cccgtgaagc
    15481 tgcaactcaa gcagtgaaag accaagtgac tgccgtttac gaagaaaaat atgcgaacca
    15541 cgaagaattt gaccgtatta tgcgtgatgt ggctgaaatc ttggaacaaa tggaacacgc
    15601 agaagtgcga cgtttaatta cagaagacaa ggtgcgtcct gatggtcgta aggtcgatga
    15661 aatccgtcct ttggatgcgg ttgttgactt ccttcctcgt gtacatggtt caggtctctt
    15721 tactcgtggg caaactcaag ctctttcagt cttgaccttg gctccgatgg gagaaactca
    15781 aatcattgat ggtttggatc cagagtacaa gaaacgcttt atgcaccact ataacttccc
    15841 tcaatattct gtaggggaaa caggtcgtta cggtgcgcca ggtcgtcgtg aaatcggtca
    15901 cggtgccctt ggtgagcgtg ctcttgctca agtcttgcca agcttggaag aattcccata
    15961 cgctatccgt ctagtagcag aagttttgga atcaaacggt tcttcatctc aagcttctat
    16021 ctgtgcggga actcttgccc ttatgactgg tggtgtgcca atcaaggcgc cagtagctgg
    16081 tattgctatg ggacttatct cagatggaaa taactacaca gtattgacag atatccaagg
    16141 tttggaagat cactttggag atatggactt caaggttgca ggtactcgtg atgggattac
    16201 agcccttcaa atggatatca agattcaagg gattactgca gaaatcttga cggaggctct
    16261 tgctcaagcc aagaaagcgc gttttgaaat ccttgatgtc attgaagcaa ccattccaga
    16321 agttcgtcca gaattggctc caactgctcc gaaaattgat acgatcaaga ttgatgtgga
    16381 caagattaag attgtcatcg gtaagggtgg agaaaccatc gacaagatta tcgctgaaac
    16441 aggtgttaag attgatatag acgaagaagg aaatgtgtct atctactcta gtgaccaaga
    16501 tgctattaac cgtgccaaag aaattattgc tggtttggtt cgtgaagcca aagtggatga
    16561 agtttaccgt gctaaagtcg ttcgtatcga gaaatttggt gcctttgtta acctctttga
    16621 taagacagat gcccttgttc atatctctga gatggcttgg actcgtacca atcgtgtaga
    16681 ggatttggta gaaatcgggg atgaagttga tgttaaggtt atcaagattg atgaaaaagg
    16741 ccgtatcgat gcctctatga aggctcttct acctcgtccg ccaaaacctg agcatgatga
    16801 aaaaggtgaa aagtctgagc gccctcaccg cccacgtcat cacaaggatc acaaacctaa
    16861 gaaagaattt acagaaacac caaaagattc agagtaagaa aaggagaaat gtatggggtg
    16921 gtggcacgaa accattgata tcgtaaaaga aaatgatcca gcggcccgca ccactttgga
    16981 ggttttgctg acttatccag gtgtcaaggc cttggcggcc caccgtctct cgcattttct
    17041 ctggaagtac gacttcaaac tcttagctcg tatgcacagt cagttttggc gcttttggac
    17101 tcagattgag attcatccag gagcccagat tgattcaggt gtctttattg accatggttc
    17161 tggtctggtg attggagaga cagcgattgt tgaaaaaggc gttcttctct atcacggagt
    17221 gactctcggg ggaacaggga aagactgtgg caaacgccat ccgactgtac gaaagggagc
    17281 cctcatatca gcccatgccc aagttatcgg gcctgtggaa attggtgaaa atgccaaggt
    17341 cggtgctgca gcagttgtcg tagcagatgt acctagtgat gtgacggttg tcggtattcc
    17401 ggccaagatt gtccgtcttc atggtaagaa agatgagcct gttattcacg aagtcgaaga
    17461 aaaacgggag tattatgtca ataaactcga gcaggctaaa gatgccagtc acagatcgtc
    17521 tggtttgtag aggataccta tatgattcaa gcaagaaaca agttaagcca agaggagcta
    17581 tctgaggcga aaaaagtaat taactgttgc caaaactatg acggtaccta tcgcgatccc
    17641 tatctctcta acatgcttaa ttttgaccca aacatgcccg cctttttcct ttattatgaa
    17701 aaaggcaaac ttgttggttt attaactgtc tatgcagatg accaagatgt agaagtgacg
    17761 atattggttc atccaggtca tcgccgtcag gggattgcgc gtgcattgtt tactagtttt
    17821 gagagagaaa cagcttcttt ccccattcgg tcagtcactt ttcagacaga acgtattttt
    17881 ttagagaatc atcctgactt tgccagtaac tggggactaa tcgaggatga agagacagaa
    17941 acttggttag gtaaggatag aagaccttat ccgttagcaa atgtttccca tcttgaagtt
    18001 ttgttagcag atagttcgta tcaggatcaa attagtcaat taaaatttca ggcattttca
    18061 gaggaacatg aatcgagaga agttgtggat agatatgtcg ctgaagctct gaaggatcca
    18121 gaaagtcgct tatatatttt gttaaaagac ggtcaggtta ttgggacttg cacggtagat
    18181 ttatcgacta atacgaatta cttctacggt ttagcaatat cggaacctga acgtgggaaa
    18241 ggctatggaa gctacttagc aaaatccctc gtcaaccaac taattgagca aaatgacaag
    18301 gaatttcaga ttgcagtgga agatagcaat gtaggtgcca aacgtttgta tgaaaaaatt
    18361 ggctttgtca aacagacaca ggtggtttat ctgaatgaga aaggagcaag ggattccgaa
    18421 gtgtagagac attcggactg aaatttactt gagctcttag tttagtgatg aaactaacag
    18481 ttcttggatt ttagctttcc tgattatgat ttatgattaa aatctatgac accatgtctc
    18541 gtgatttgcg agaatttgtc ccgattgagg acggcaagat caagatgtat gtttgtgggc
    18601 caaccgtgta caactatatt cacgtgggaa acgcccgttc gacggtagct tttgatacga
    18661 ttcgtcgcta ttttgagtac cgtgggtata aggttgccta tatttccaat tttacagatg
    18721 tggatgataa gattatcaac cgtgccaggg aagaaggcat cacacctcag gaggttgcgg
    18781 ataagtacat cgctgccttt cgtgaggatg tgacggcctt aggcgtgaaa cctgcgactc
    18841 gccatccgcg tgtagtggag tttatggcag acatcatccg ttttgtggaa gacttgatcg
    18901 agaaaggctt tgcctatgag agtcaagggg atgtctattt ccgtgtagaa aaatcccaca
    18961 actatgctaa attggctaat aaaaccttgg aagatttgga gctaggtgct tcaggtcgta
    19021 ccgatgaaga aacggctcgt aaggaaaatc ctgtagattt tgctctatgg aaatcttcca
    19081 aaccaggtga gatttcttgg gatagtcctt ggggacctgg acgtccgggt tggcatattg
    19141 agtgttcagt catgtcgaca gagattttag gtgataccat tgatatccac ggtggtggag
    19201 ctgacctaga gtttccacac cacaccaatg aaattgccca atctgaagct aaaacaggca
    19261 aggcttttgc taactactgg atgcacaatg gctttgtcaa tatcgacaat gtcaaaatgt
    19321 ctaagtcctt gggtaacttc attacggtac acgatgccct taaaactctt gatgggcaag
    19381 tacttcgttt cttctttgcg acccagcact accgtaagcc tatcaacttc acggaaaagg
    19441 cagttcgcga tgccgagacc aatctcaagt atctgaagaa tacttacgaa caaccattta
    19501 caggaaacgt ggatgcccaa gagttacaaa actttaaaga taagtttgta gcagctatgg
    19561 atgaagattt taatgctgcc aacggtatca cagttgtctt tgaaatggcc aaatggatca
    19621 actcagggaa ctatgatgca agtgtcaagc aagctcttgc agatatgtta gaaatttttg
    19681 gaattgtctt tgttgaggaa gttttggatg cagagattga agacttgatt caaaaacgcc
    19741 aagaggcgcg tgccaatcga gactttgaga cagcagacca aatccgtgac caattggtta
    19801 ctcaaggaat taagctcctt gataccaagg atggagtgag gtggacacgt gattgatgtc
    19861 aatctcatta acgggattgc gctagccttt gagggggatg cggtgtattc tatgtatatt
    19921 cgccgtcacc tcatcctcaa aggtatgacc aaacccaata aactccatca agaagcaacc
    19981 aagtatgtgt cagccaaggc tcaggctcgc ctgattgctc tcatgttgga ggagcaggtc
    20041 ctaacggaaa aagaagaaga aatctacaaa cgtggccgca ataccaatag ccacacaaag
    20101 gctaaaaatg cagatgtcgt gacttatcgt atgtccacgg gatttgaagc ggttatgggc
    20161 tatctccata tgactgagaa tctggaacgt cttgagagtt tggtttcatg gtgcatccaa
    20221 aaagtggagg gctagaacat gagggaaaaa gaactacaag actggtttcc tgaggctcgg
    20281 atttcagacc aaccagtaga gaaagagggc tatctcacgc tccctttagc ttctcagcag
    20341 tggattttgc tggaggaagc tgggctcagc gagcgtgaaa agcagttggt tgcccttttg
    20401 acccagcagg agcaggctcg ttcgctaaac ccttggtatt cctatctggt tgaaggcaag
    20461 ggacaggcac cgcaagtttt taaaaagatt cagttggttt attgccatct ttcttatttt
    20521 cagcaggaaa atctggcttc ttggctagat atgatgcgga ctctttttcc gaattgtcag
    20581 acagtgctac aggtcggagc tcaggattat gttttcgtgc ttcaacaaga caaatacact
    20641 tctgtaagag atattttaag tgatacgatt gaagcggttg agtatgactt tggacttcgt
    20701 ctttctatca tgttgggtca ggtttggtct cagacaggac atcaagccct atcagactta
    20761 atcaaagctg agcgggattt gttcaagaca tggtggcgtc agggtcacca aggtgttcat
    20821 actttttctc agctctatct ttggagtatg ggagaaagac tcgtggactt gaagccaatt
    20881 aaagaatgtc tacaccagat gattttggat caagatcaga ttcaggaaat cattctctct
    20941 ctttgggaaa atagtgctgt tctcactaaa acagcccagc aactctatct gcaccgcaat
    21001 tctctccaat acaagattga taaatgggaa gagttgacag ggcttcagtt gaaagagttg
    21061 accgacctga ccttgtgtta tcaattgatt ttaggttctt tgtcaactat agttggtttg
    21121 taaagaagtt aatatttgga gaagaggatt gccatcttct ccattt
//
LOCUS       DAYYYC010000034        21109 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.034, whole genome shotgun sequence.
ACCESSION   DAYYYC010000034 DAYYYC010000000
VERSION     DAYYYC010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21109
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.034"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            342..1385
                     /locus_tag="ACHBV5_001387"
     CDS             342..1385
                     /locus_tag="ACHBV5_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HFM9967170.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIIARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            1552..3639
                     /gene="topA"
                     /locus_tag="ACHBV5_001388"
     CDS             1552..3639
                     /gene="topA"
                     /locus_tag="ACHBV5_001388"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFM9967171.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEENIK"
     gene            3745..4104
                     /locus_tag="ACHBV5_001389"
     CDS             3745..4104
                     /locus_tag="ACHBV5_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HFM9967172.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4197..4829
                     /locus_tag="ACHBV5_001390"
     CDS             4197..4829
                     /locus_tag="ACHBV5_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFM9967173.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGVLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQVGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            4873..5529
                     /locus_tag="ACHBV5_001391"
     CDS             4873..5529
                     /locus_tag="ACHBV5_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HFM9967174.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5599..6630
                     /locus_tag="ACHBV5_001392"
                     /pseudo
     CDS             5599..6630
                     /locus_tag="ACHBV5_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            6642..7679
                     /gene="leuB"
                     /locus_tag="ACHBV5_001393"
     CDS             6642..7679
                     /gene="leuB"
                     /locus_tag="ACHBV5_001393"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HFM9967175.1"
                     /translation="MAKKIVALVGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAWPPLPDETLKASREADAILLATIGSPQYDGAVVRPEQGLMTLRKELNLYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSV
                     PDIAGQGIANPISMILSVSMMLRDSFGGYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7676..7945
                     /locus_tag="ACHBV5_001394"
     CDS             7676..7945
                     /locus_tag="ACHBV5_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFM9967176.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            7949..8308
                     /gene="leuD"
                     /locus_tag="ACHBV5_001395"
     CDS             7949..8308
                     /gene="leuD"
                     /locus_tag="ACHBV5_001395"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HFM9967177.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8470..9094
                     /locus_tag="ACHBV5_001396"
                     /pseudo
     CDS             8470..9094
                     /locus_tag="ACHBV5_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004899133.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            9257..11187
                     /locus_tag="ACHBV5_001397"
                     /pseudo
     CDS             9257..11187
                     /locus_tag="ACHBV5_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
     gene            11174..12490
                     /locus_tag="ACHBV5_001398"
     CDS             11174..12490
                     /locus_tag="ACHBV5_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HFM9967178.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            12665..13651
                     /locus_tag="ACHBV5_001399"
     CDS             12665..13651
                     /locus_tag="ACHBV5_001399"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFM9967179.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13715..13786
                     /locus_tag="ACHBV5_001400"
     tRNA            13715..13786
                     /locus_tag="ACHBV5_001400"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13748..13750,aa:Arg,seq:ccg)
     gene            13969..14667
                     /gene="rnc"
                     /locus_tag="ACHBV5_001401"
     CDS             13969..14667
                     /gene="rnc"
                     /locus_tag="ACHBV5_001401"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFM9967180.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14658..18197
                     /gene="smc"
                     /locus_tag="ACHBV5_001402"
     CDS             14658..18197
                     /gene="smc"
                     /locus_tag="ACHBV5_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFM9967181.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRSS
                     LSQEKSDKESSLALLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKAGQQKAELETAKEQVQK
                     LLADYQVCAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLEIILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDLLKR
                     NRSGRATFLPLTTIKARTISSQNQDTIAASPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEVIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18194..18988
                     /locus_tag="ACHBV5_001403"
     CDS             18194..18988
                     /locus_tag="ACHBV5_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFM9967182.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLVSYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEDGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELVKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            18988..19806
                     /locus_tag="ACHBV5_001404"
     CDS             18988..19806
                     /locus_tag="ACHBV5_001404"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFM9967183.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLQAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            19810..21099
                     /gene="ftsY"
                     /locus_tag="ACHBV5_001405"
     CDS             19810..21099
                     /gene="ftsY"
                     /locus_tag="ACHBV5_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFM9967184.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVTEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
BASE COUNT         6681 a         3664 c         4740 g         6024 t
ORIGIN      
        1 tagagattac aaggcttgtt taagaaagaa ttcaaagacc ttgacaaata aaaataaaat
       61 ggttattata aaaaatggtc tgaaatagat gatgatactt ttcgaaaatc tttttacatc
      121 agctcagctt tgccttgctg tgttttgagc aagctacggt tagcttccga gtttgatttt
      181 catttactag aaatgaaact gatgagagat atcagtagac atctgagtca ggatattatg
      241 gaaaatgata aaaagagctc gtgagattgg catatcagac tactaaagta ttgagtttgt
      301 taggatttta gcgactagtt agctgggaaa ggaagatatt tgtgacaaat aataaactgt
      361 attcgttgat agaatttaga aataaaatat atgaagaatt agaactttcc agaagtgatt
      421 tagcgatttt actatgtgcc atgcttatcg cctctatcgg attaaatatg gattcgactc
      481 ccgtgattat tggagccatg ttaatctctc ctttgatgac acctattctg ggagtggggc
      541 tctctctagc tatatttgat tttaaattgt taagaaaatc ttttaaaata ttagctattc
      601 aaattcttgc cagtctaata gcttcaacac tttattttta tctttctccc atttcgtatg
      661 ctagttcgga gattattgct agaacctctc cgactatttg ggatgttctc attgcttttg
      721 taggagggat agcaggtatt attggtgcta ggaaaaaaga gaccaataat attgttcctg
      781 gtgttgctat tgcaaccgcc ttgatgcctc ctctttgtac agtaggttat gctattgctt
      841 ctgctaatct aaaatttatc ataggctcct cttacctatt cctcatcaat tgtagcttta
      901 ttgtcattgc gacttatata ggtgttaggt tgatgatggt taagaaacat tattttaaag
      961 ataatgaaga agactctaaa atgcgtagga ttttgcttct agttgctgtt ttgctgatga
     1021 ttccgagttt catctctgca acgactttag tgagagaaac gttgaaaaaa gagtccctta
     1081 agaaatttat atcagagcag tttcaggggc ataatatttt gaaaaaaacc tattctaaaa
     1141 agactcatac cctaaagcta accatttcag gaaattattt gacagaagaa gaactcgata
     1201 tgatttcaag taagagaggt gactatggtt taagtgatgt ttctgttcaa gtttcacaat
     1261 tgtctgattc agaacaactt agtaaggaag aactggtgga gtatttcttc cagtatatca
     1321 aggataagga agcaaaagaa aaggaaaaag ctaataagtt ttatacagag tctgaggagc
     1381 aataatttct tgagaatagc tggtttttct cgtgagtctt ctatgtatat caaaggaaga
     1441 ctgaggtttt aagtataaaa cttttcttct attatagtag ctaagtcttg acagggttca
     1501 aaaaatggtt tacactttat aaagtttatt actttgaaaa ggtgtgatac tgtggctacg
     1561 gcaacaaaaa agaaaaaatc aacagttaaa aaaaatctag tcatcgtgga gtcgcctgct
     1621 aaggccaaga cgattgaaaa atatctaggc agaaactaca aggttttagc cagtgtcggg
     1681 catatccgtg atttgaagaa atccagtatg tccgttgata ttgaaaataa ttatgaaccg
     1741 caatatatca atatccgagg aaaaggccct cttatcaatg acttgaaaaa agaagctaaa
     1801 aaagctaata aagtttttct cgcgagtgac ccggaccgtg aaggagaagc gatttcttgg
     1861 catttggccc atattctcaa cttggatgaa aatgatgcca accgtgtggt cttcaatgaa
     1921 atcaccaagg atgcagtcaa aaatgctttt aaagaacctc gtaagatcga tatggacttg
     1981 gtcgatgccc aacaagctcg tcggatcttg gatcgcttgg tagggtattc gatttcgcct
     2041 attttgtgga agaaggtcaa gaagggcttg tcagcaggtc gcgttcagtc cattgccctt
     2101 aaactcatca ttgaccgtga aaatgaaatc aatgccttcc agccagaaga atactggaca
     2161 gttgatgctg tctttaaaaa gggaaccaaa caatttcatg cttccttcta tggagtagat
     2221 ggtaaaaaga tgaaactgac cagcaatgac gaagtcaagg aagtcttgtc tcgtctgact
     2281 agtaaagact tttcagtaga tcaggtggat aagaaagagc gcaagcgcaa tgctccttta
     2341 ccctatacca cttcatctat gcagatggat gctgccaata aaatcaattt ccgtactcga
     2401 aaaaccatga tggttgccca acagctctat gaaggaatta atatcggttc tggtgttcaa
     2461 ggtttgatta cctatatgcg taccgattcg actcgtatca gtcctgtagc gcaaaatgag
     2521 gcggcaagct tcattacgga tcgttttggt agtaagtatt ctaagcacgg tagcaaggtc
     2581 aaaaacgcat caggtgctca ggatgcccat gaggctattc gtccgtcaag tgtctttaat
     2641 acaccagaaa gcatcgctaa gtatctggac aaggatcagc tcaagctata tacccttatc
     2701 tggaatcgtt ttgtggctag ccagatgaca gcggccgttt ttgataccat ggctgttaaa
     2761 ttgtctcaaa aaggggttca atttgctgcc aatggtagtc aggttaagtt tgatggttat
     2821 cttgccattt ataatgattc tgacaagaat aagatgttac cggacatggt tgttggagat
     2881 gtggtcaaac aggtcaatag caaaccagag caacatttca cccaaccgcc tgcccgttat
     2941 tctgaagcaa cactgattaa aaccttagag gaaaatgggg ttggacgtcc atcaacctac
     3001 gcgccaacca ttgaaaccat tcagaaacgt tattatgttc gcctggcagc caaacgtttt
     3061 gaaccgacag agttgggaga aattgtcaat aagctcatcg ttgaatattt cccagatatc
     3121 gtaaacgtga ccttcacagc tgaaatggaa ggtaaactgg atgatgtcga agttggaaaa
     3181 gagcagtggc gacgggtcat tgatgccttt tacaaaccat tctctaaaga agttgccaag
     3241 gctgaagaag aaatggaaaa aatccagatt aaggatgaac cagctggatt tgactgtgaa
     3301 gtgtgtggca gtccaatggt cattaaactt ggtcgttttg gtaaattcta cgcttgtagc
     3361 aatttcccag attgccgtca tacccaagca atcgtgaaag agattggtgt tgagtgtcca
     3421 agctgtcatc agggacaaat tattgagcga aaaaccaagc gtaatcgcct cttctatggt
     3481 tgcaatcgct atccagaatg tgaatttacc tcttgggaca agcctgttgg tcgtgactgt
     3541 ccaaaatgtg gcaacttcct catggagaaa aaagtccgtg gtggtggcaa gcaggttgtt
     3601 tgtagcaaag gcgactacga ggaagaaaat attaaataag aggaggggcc cgaaagtaaa
     3661 tttcaggctc cttttggtta gaacttgaca aaatacatca ttttatgcga aactagaaga
     3721 agattatttt aactaggaga agttatgcgt cttatctatc tgataattgg ttttttatca
     3781 ctggccttgg ctattgttgg ggttgtttta cccttgttgc cgacaacgcc tttccttttg
     3841 ttgtctattg cttgtttctc cagaagttcc aagcgtttcg aagactggct ttatcatacc
     3901 aagctctatc aaacatatgt agctgatttt cgcgagacta agtctattac gcgtgaacga
     3961 aagaaaaaaa tcatcgtctc tatctacgtc ttgatgggaa tttctattta ttttgcacct
     4021 cttttaccag tcaaaatcgg tctgggtgct ttgaccatct ttatcaccta ttatctcttc
     4081 aaggtcattc cagacaaaga ataattaaaa cagtagttat ttcccttgat aaaattgaaa
     4141 gcatattcat aacaatatga tataataaat ttgaagtaat attcaaggag aatcaaatga
     4201 tttacgaatt ttgtgctgaa aatgtgacct tgcttgaaaa agcgatgcag gctggagctc
     4261 gtcggattga actctgtgat aatctagcag ttggtgggac aacccccagc tatggagtga
     4321 ctaaggcagc ggttgaactg gcagctaact acgatacaac catcatgacc atgattcggc
     4381 cacgtggtgg tgactttgtc tataatgacc tagaaattgc tatcatgcta gaagacattc
     4441 gtttgactgc tcaggctgga agtcaagggg ttgtatttgg agttttaact gctgataaaa
     4501 agttggataa gcctaatctg gaaaagttaa ttgctgcatc aaaaggaatg gaaattgtct
     4561 ttcacatggc ctttgatgaa ctaagtgatg aagatcaacc ggaagctatt gactggctca
     4621 gtcaagtcgg tgtcactcgt atcctaactc gtgctggtgt gtctggcgac tccttagaaa
     4681 aacgttttgt tcactatcac agaattttgg agtacgctaa aggtaaaatt gaaattctac
     4741 caggtggggg gattgacctt gacaaccgtc aaacctttat cgaccaggtg ggggtaacac
     4801 agttgcatgg tactaaggtt gttttttaaa aaatagaaag gaactgctag ctttgggtag
     4861 cagttttcac ttatgtttga aatttttaaa tcctatcaat ttaatcaaga aaaggctcat
     4921 gattatggtt ttatagaaaa tagcgaagtc tggacatata gttgccagat tttgcaaggt
     4981 gactttgtca tgactgtgtc catcactgct gataatgtga actttcaagt ctttgaccaa
     5041 gagactggcg acctctatcc tcacgtttat atggaaagca tgaggggaag ttttgtcgga
     5101 aatgtccgtg aggcttgtct ggagattctt taccagattc ggaaggcttg ttttgatgtg
     5161 caagatttta tctgtcatca gactaagcgt atcatgactc aagttcagga aaagtatgga
     5221 aaccagttgg agtatctgtg ggaaaaatcg cctgatacag ctgtattgcg ccatgaaggc
     5281 aatcaaaagt ggtatgccgt cttgatgaaa atctcttgga ataagctgga aaagggcaga
     5341 gaaggacaag tggaagcagt caacctcaag catgaccaag tagctaattt actttcacaa
     5401 aaggggattt atccagcctt tcatatgagc aagcgctact ggattagtgt gtcccttgat
     5461 gatactttat cagatgaaga agtactggaa ttgatagaaa aaagttggaa cttaacctct
     5521 aaaaaatgaa atattttaat aattttcatg aactttcaat tagctaaata ttctttactg
     5581 aagaaatttt cagaaaatat aggatttacc acactagagg aatatggtgc atcttcaaat
     5641 acctgattga gaatgtcaag acggatcgtc agatcatcta ttcgcctcac tgtcatgatg
     5701 acctcggaat ggcagtggca aatagccttg ctgctgtcaa gaatggtgca ggacgtgttg
     5761 aagggactat caatggtatt agggagcgag ctggaaatgc tgctttggaa gaaattgcag
     5821 tggctctcaa tattcgccaa gattactacc aagtagaaac cagtattgtc ctaaatgaga
     5881 ccatcaatac gtcagaaatg gtttctcgct tctctggtat tccagttcct aaaaacaaag
     5941 ccgtcgttgg tggcaatacc ttctcccacg aatctggtat tcaccaagat ggagtcctta
     6001 aaaatcctct cacttatgag atcatcacac ctgaattggt tggtgttaag attccgcttg
     6061 ggtcgccatg cttttgttga gaaactgaga gaattggccc tagattttac agaagaggat
     6121 atcaaaccac tctttgctaa gttcaaggca ctggccgata agaagtaaga aatcacagat
     6181 gcagatattc gagctttggt agctggaagc atggttgaaa atccagaagg cttccacttt
     6241 gatgatttac aacttcaaac tcatgcagat aatgacattg aagcgctcgt tagcctagcc
     6301 aatatggatg gtgagaaagt cgaatttaat gcgacagggc aaggttccgt tgaagcaatc
     6361 tttaatgcta tcgataagtt ctttaaccaa tctgttcgtt tggtgtccta cactatcgat
     6421 gcggtaacag atggaatcga tacccaggat cgggttttgg tcactgttga aaacagagat
     6481 acagaaacca tctttaatgc agcagggctt gattttgatg tgttgaaggc ttctgctatt
     6541 gtctatataa acgctaatac ctttgttcaa aaagagaatg caggtgagat gggacgcagt
     6601 gtttcttacc acgatatgcc tagtgtgtaa aggagaaggc tatggcaaag aaaatagtag
     6661 ctctagtagg agacggaatt ggcccagaaa tcatggaggt tggtttagaa gttctggagg
     6721 ctctagctga aaaaacaggt tttgactatg agattgacag acgaccgttc ggaggtgcag
     6781 atattgatgc agcatggcct cccttacctg atgaaaccct taaggcaagt agggaagcag
     6841 atgctatcct actagcaact atcggtagtc ctcagtatga tggagcagtg gttcgccctg
     6901 aacaaggcct gatgactctc cgtaaggaac ttaatcttta cgctaatatt cgtcctgtaa
     6961 aaatctttga cagtctcaag catttgtcac cactcaaact ggaacgaatt gctggtgtag
     7021 actttgtcgt ggtgcgtgaa ttgacaggcg ggatttactt tggagatcat attcttgaag
     7081 agcgcaatgc gcgtgatatc aacgactata gctatgagga agtggagcgg attattcgca
     7141 aagcctttga aattgcaaga aatcgcagaa aaatccttac tagtatcgat aagcaaaatg
     7201 ttctagcgac ctcaaaactc tggcggaaag tagctgagga agtcgcacag gatttctcag
     7261 atgtaacctt ggaacaccag ctggtagact cagctgctat gcttatgatt accaatcctg
     7321 ctaagtttga tgttattgta acggagaatc tttttggaga tattttatct gatgaatcaa
     7381 gcgtcttatc tggtacactt ggggttatgc catcagccag tcattctgaa aatggaccaa
     7441 gtctctatga acctattcac ggttcagtac ctgatattgc aggtcaagga attgccaatc
     7501 ctatttccat gattttatca gtttccatga tgttaagaga tagtttcgga ggttatgagg
     7561 atgcagagcg tatcaaacgt gctgttgaga caagtttggc ggcaggaatt ttaacgagag
     7621 atataggagg tcaggcttca acaaaggaaa tgacggaagc tattattgca aggttatgaa
     7681 gttagacgaa aaaattactc tagtcctttt gatttggaat gtcatcattt tcttgattta
     7741 tggcattgac aaattcaagg caagaagaag agcttggcgc atcccagaga aaatcttact
     7801 cattttagcc cttacttgtg gtggttttgg ggcctggtta gctggaatca cttttcacca
     7861 caagactcga aaatggtact ttaaaacagt ttggtttctt gggatggtga ccacactagt
     7921 agccttatat tttatttgga ggtaatggat ggcagggtct tcgagggaac acgctgcttg
     7981 ggctctagcg gactatggtt ttaaggtcgt gattgcagga tctttcggtg acattcatta
     8041 caataatgaa ctcaataatg gcatgttgcc aatcgttcag cctagagagg ttagagagaa
     8101 actagcccag ctaaaaccaa ccgaccaggt aactgtggac ttggaacaac aaaaaatcat
     8161 ctcaccagtt gaagaattca ccttcgagat agatagcgag tggaaacata aactcctaaa
     8221 tagtttggat gatatcggta ttaccttgca gtatgaagag ttgattgctg cttatgaaaa
     8281 acaacgacca gcctactggc aggattagaa aaaatagaaa aggaaatata gtaaactgaa
     8341 ataagatgta aacaaatgaa ttggagctta acatccattt ccagcaattt tttagaaact
     8401 acagtggact attctggatt caacacatta taaaattatg acaaaacaca ttcacaagaa
     8461 ggctacgaca ttttaaaagg tgagggcgga tgtatcgttt gccctactaa agttggttac
     8521 attatcatga ccagcgacaa ggcaggactt gagcgtaagt ttgcagccaa agaaggtaag
     8581 cgtaacaaac caggtgttgt tctctgcggt agcatggatg aactttgcgc tttagcgcaa
     8641 ctcaacccaa aaattgaagc attctactaa aaacattggg atgaagatat tcttcttggt
     8701 tgtatccttc cttggaaacc agaagccttt gaaaaactca aagcatacgg ggatggccgt
     8761 gaagaactta tgactgatgt acgtggtact agctgttttg ttatcaagtt tggaaaagca
     8821 ggtgaacaat tggctgccaa gctttgggaa gaaggtaaaa tggtctacgc ctcatatgct
     8881 tcaatgacaa aacgattgaa actcgctatg agagcaaggt gtaatggtgt ctatggtcga
     8941 taaggacggc aaactcatcc cagaacaagg aggagcacgt tcaacctcac cagcaccagt
     9001 tgtgatccgt aaagggcttg acattgataa aatcatgatg cacctgtcag acacctttaa
     9061 cttatgggac taccgtcagg ttgagtatta ttaggataga gaagaagtct agtgttaagg
     9121 acattacagc tcataatact aggctttttt atagaaattc ttttcttttt ctataggata
     9181 tggtattcta tgtagaaaat atatgttaat aagtaatgcc aatatttaaa catcattagt
     9241 aaaaggagtt agattgatga ataaaagaaa agttagttta gaagattttt ataaatggta
     9301 tagtctaaat aaagaagagt tattaaataa ggcaactgtt ggtgaaaagt ttaatgataa
     9361 attaaaagaa gagtttctcc aggaatggcc tttggatagg attttaacaa tgtcaatcga
     9421 tgaatatgta ataggaaagg gacagcaaaa taagtcttta tgctacgctc ttgagaaggg
     9481 aaaatacaaa aatctatttc ttggaatttc tggtggctca gcttcaaaat ttggtattta
     9541 ttggaataaa aaaacaaaca aatataaaga tcaagctaat aatgagattt cagagttgga
     9601 tcagcgattt tcaaaattaa aatcagattt gtatgaaatt atcaaagaag gtattcgttt
     9661 taactttgaa aatcctattt ttgatatgaa aagatcaaca aatgaattta ttggtcgttc
     9721 tgctatggtg acaaaattac tttgtatcta ttctgaggga gattctttct ttggtgtaaa
     9781 tattaatagt cagaaagaat tttggaacca ctttgtttct cagacaaatc aaggtggacc
     9841 ttatctgcaa aatcataaaa taattgaact ggtgccaaaa cttatcctga gttggagcca
     9901 tcgaaattag gaactatgct ttttgagtat tctaagcttt ttatggaaaa taaggaagac
     9961 aatagtacaa tggattcatc aaacaatttt cgtcatcaat taactcaatc tctattaaag
    10021 tctccaaacc ttatccttcg tggtgctcct ggcacaggaa agacttatct tgctaaagaa
    10081 attgccaaag aattaacgga tggcaacgaa gaccaaatcg gatttgtaca atttcaccca
    10141 tcatatgatt atacggattt tgtagaaggt ttaagaccag tatcaaatgg ggatggagct
    10201 attgagttta ggctacagga cggtattttt aaagattttt gtcagaaagc aaaagaaacc
    10261 caattgattg gaggacaaga taattttgat gaggcttggg attcttactt agaatatata
    10321 aatgttgctg aagaaaaaga atatataaca aaaacatctt acttatctgt taatagtaga
    10381 caaaatttgt cagtaaatta tgatagtggt gttccaggat ggtcactacc tagcaaatat
    10441 gtttacgagt tgtataaaga taaaaattat aataagcaag aatactacaa aagtggtgga
    10501 aaaactgtcc tagaaacatt gagaaagaga tttggtttga aagactatgt ttccccaaca
    10561 gaaattgata ctgataagaa attcgtcttc atcatcgatg aaatcaatcg tggggagatt
    10621 tctaagattt ttggcgaact ctttttctct atcgaccctg gctatcgtgg tgaaaaagga
    10681 agtgtttcta cccaatatgc aaatctacac gaaactgatg aaaagttcta tatccccgaa
    10741 aatgtttaca tcatcggaac tatgaatgat attgatcgtt cagtggatac ctttgatttt
    10801 gctatgcgtc gtcgttttcg ttttgttgaa gttactgccg agggtcaagt tggcatgttg
    10861 gataaagagc tgaatatcca tgcagaagaa gcaaaaattc gtctaagaaa cttgaacgct
    10921 gctatcgaaa atgttcagga attaaacagt cattatcata ttggaccaag ttattttctt
    10981 aagttgaagg atgtagattt tgactatgaa ttactctggt ccgattatat taagcctctc
    11041 ctagaagact acttgcgagg ttcttatgat gaggttgaaa ctttggaaac tttgaaaaaa
    11101 gcatttgaac tgacaaataa tgagcaaaaa gatcaggcag tagctgatga caatgaaggt
    11161 gatgaaaacg atgatgcgga ttactgataa tcaacacaag attattaaag aaaaatttgt
    11221 tgaagaatat cctaaactaa gcaatcttct tttagacaga accttggaaa gtctatccca
    11281 agatgaacgt attttcattt ttccaaatga tttgactcat actcctgatt tggataagga
    11341 ccaaaagatt tttgaaacag tcaatcagaa aatcaagaca gggaacgtga ttggttttct
    11401 tggatatggt caggaaagat taacgatttc ctcacgattt tctgatgaga gtaatgacca
    11461 ttttttgcat tatctcttaa acaaggttct tcatatcaat ctcactagtt tagatgttgc
    11521 tttgtctcgt gaagagaggc tttatcaact tttggtgtat ctctttccca agtatctaca
    11581 agctgctatt cgaaaaggtc tttataagga atatcatcga ttttctcata acgacagtaa
    11641 tgttaaggga gtgattgatg taagaagcca tctcaagaaa aatcttcctt tcacgggaaa
    11701 tattgcctac gcaacgagag agttcaccta tgataatccc ctcatgcagt tggtccgtca
    11761 cactattgaa tacattaaga atcagaaaag cattggtcaa ggggtactag ataatctctc
    11821 aactagtcgt gaaaacgtat ctgaaatcgt gcgtgtaacg ccctcttata aactagctga
    11881 tcgtgctaag attattcggg gaaatcaatc taaacctata cgtcatgcat actttcacga
    11941 gtacagaaac ttacaagaac tttgtctgat gatcctaaac caagaaaagc acggtttagg
    12001 gtatcaagat caaaaaatct atggtattct ctttgatgtt gcctggcttt gggaagagta
    12061 tgtttacacc ttgttgccaa aaggttttgt acatcccaga aataaggata agacggatgg
    12121 aatttcagta ttttctgttg ggaaacgaaa agtatatcca gatttttatg acagagaacg
    12181 aaagattgtt ctagatgcaa aatataaaaa actggaattg actgaaaaag gaatcaaccg
    12241 tgaggactta ttccagctga tttcctattc ttatatttta aaagctgaga aggctggact
    12301 gatttttcct agtatggagc agtcagtaaa tagtgaaata ggaaaagtag ctggctatgg
    12361 agctcaattg aagaagtggt ctattcgaat ccctcagaat gcctcattct atagtacatt
    12421 ttgtaaaatg atggaaaatt cagaagaaaa ttttaaagcg attattgatg aagaagtggg
    12481 gagaaaataa tttcccctct ttcttttatt tttaacacaa gtaaaacccg aacgatatat
    12541 tttaattcat aaaataattt gacaaaaact gtactttggt ttataataaa ttaaggaaac
    12601 gtcggaaaag gcgtagtgat gcaagagcat aggtaggtca ttacaaaaga aacgagacat
    12661 cgatatgtta aatgaatttc caatttttga ttacgaagat attcaattga ttccaaataa
    12721 atgtgtcatt aaaagccgtg cagaagcgga tacaagtgtc actttaggaa atcacacctt
    12781 taaactacct gttgtgccag cgaatatgca gacgattttg gatgaaaatg tagcagagca
    12841 actggctaaa ggtggttact tctacattat gcaccgtttt gatgaggcag gacgcattcc
    12901 ttttattaaa cgaatgcacg atcaagggct cattgcttct atctctgtcg gtgttaagga
    12961 ttatgagtat gatttcgtta gacagctcaa ggctgatgct cctgagtata tcactattga
    13021 tattgctcat ggtcatgcgg atagcgtgat ttctatgatt caacacatca agaaagaatt
    13081 gccagatacc tttgtcattg ctggaaatgt gggaacacca gaagctgtgc gtgaattgga
    13141 aaatgctggt gcggatgcta ctaaggtcgg aatcggtcct ggtaaggttt gtatcaccaa
    13201 ggttaagact ggttttggta caggtggttg gcagttggct gctctacgct ggtgtgccaa
    13261 ggctgcgcgt aaaccgatta tcgctgatgg aggaattcgt actcacggtg atattgctaa
    13321 gtctatccgc ttcggtgcta gcatgatcat gattggttcc ctctttgcag gacacattga
    13381 aagtccaggg aaaacgattg aagtcgatgg tgaacagttc aaagaatatt atggttcagc
    13441 ctcacaatat caaaaaggtg cttacaaaaa tgtggaaggc aaacgtatct tgcttcctgc
    13501 taaaggtcat ctgcaagaca ctttaactga gatggaacaa gaccttcaaa gtgctatttc
    13561 ttatgcaggt ggacgtcagg ttgctgacct taaacacgtt gattatgtga tcgtgaaaaa
    13621 ctccatctgg aatggggatg cttcccacta agacggggtc tttgaccaaa aaacttgtta
    13681 ttagagcaaa tttctgttat aataaaacaa gtttccaccc ttagtgtaat ggatatcacg
    13741 taagattccg gttcttgaga tgggggttcg attccctcag ggtggatgta aacatcctaa
    13801 aaagccttta atagggcttt tttctttatc ctgacccaaa tttgccgcta aaactgagaa
    13861 tctctgtcta aagaattccc aaatgctttc cagtcccgtt ttagagtgac tcagggggct
    13921 ttttttgata taataaaaag gactattatc agttagaaag aggttggtat gaaagaatta
    13981 caaactgtac taaagaatca ttttgcaatc gaatttgcag acaaaaattt actggaaact
    14041 gcctttactc atacgagtta tgccaatgag caccgcctct taaaaatttc acacaatgaa
    14101 cgcttggaat ttttaggaga cgctgttcta cagttattga tttcagaata tctatataaa
    14161 aaatatccta aaaagcctga aggtgaccta tcaaaactcc gtgctatgat tgtccgtgag
    14221 gagagtttag ctggttttgc gcgtgattgc cagtttaacc agtttatcaa gttgggtaaa
    14281 ggggaagaaa aatcaggtgg tcgcaatcgt gacaccattc ttggtgatgc ctttgaagcc
    14341 tttcttggtg cccttctttt ggataaggat gtggccaagg tcaaggaatt tatctatcaa
    14401 gtcatcattc ctaaggttga agcaggcgag tttgagatga ttacagacta taaaacccat
    14461 ctccaagagt tgcttcaggt caatggtgat gtggctattc gttatcaggt gatttctgaa
    14521 acagggcctg ctcatgataa ggtctttgat gtagaagttc ttgttgaagg taagagcatc
    14581 ggtcaaggcc aaggtcgttc taagaaatta gcagagcagg aagctgccaa aaatgccgtt
    14641 gagaaggggc tggattcatg tatttaaagg aaatcgaaat tcaggggttc aagtcttttg
    14701 ctgataagac caaggtcgtt tttgaccaag gtgtgacggc agttgttgga cccaatggat
    14761 ctggaaagtc caatattaca gaaagtctgc gttgggcttt gggggagtct agtgtcaaga
    14821 gtctccgtgg gggcaagatg ccggatgtca tctttgctgg aaccgaaagt cgcaaaccgc
    14881 tcaattatgc ttctgtagtt gtgactctgg ataatcatga cggatttatc aaggatgcag
    14941 gtcaagaaat cagggtggaa cgccatatct atcgtagtgg agatagcgaa tacaagattg
    15001 acggcaagaa agtccgtctg cgtgatattc atgacctctt cttggatact ggattgggac
    15061 gagattcctt ctctattatt tcccaaggga aggttgagga gatttttaat tccaagcctg
    15121 aggaacgacg agctattttt gaagaagctg ctggagtttt aaaatacaag actcgcagaa
    15181 aagaaaccga gagtaaactg cagcaaactc aggataatct ggaccgctta gaggacatta
    15241 tctacgagtt ggataatcaa atcaagcctc ttgaaaagca agctgagaat gcccgtaagt
    15301 ttttagactt ggaaggacaa cgtaaggcta tttatttaga tgttctggtt gctcaaatca
    15361 aggaaaataa ggctgaacta gagtcgacag aagaagagtt ggctcaggtt caagaactct
    15421 tgatgagtta ttaccaaaag cgtgaaaaat tagaagaaga aaatcaaact cttaaaaagc
    15481 aacgccaaga tttacaggct gaaatggcca aagaccaagg cagtttgatg gatttgacca
    15541 gtctgattag tgacttagag agaaaattag ccctatcgaa actggaatct gagcaagtag
    15601 ccctcaatca acaggaagca caagcccgtt tggctacttt ggaggataag agaagttcac
    15661 tcagccaaga aaaatctgat aaagaaagct ctttagccct cttggaagaa aatctagtcc
    15721 aaaataatca aaaactcaat cgattagagg ctgaattgct agctttttca gatgatcctg
    15781 atcagatgat tgagctctta cgtgaacgct ttgtggccct tttacaagaa gaagcagatg
    15841 tctcaaacca actgacccgt attgagaatg agttggaaaa tagtcgtcag ctttctcaaa
    15901 aacaagcaga tcaactagaa aagctgaaag aacagttggc tacagctaaa gagaaggctg
    15961 gtcagcaaaa ggctgagctt gaaactgcca aggagcaggt tcagaaatta ttggccgact
    16021 atcaagtctg tgctaaggag caagaggagc agaaaacttc ctatcaagct caacaaagtc
    16081 aactctttga ccgtctggat agtctcaaaa acaagcaggc tagagcgcaa agtttggaaa
    16141 ttatcctgag aaatcatagt aacttttatg caggtgttaa gagtgttctc caagagaaag
    16201 atcgtctagg tgggattatt ggagcagtta gtgagcacct gacctttgat gtgcattatc
    16261 aaactgccct agagattgcg cttggagcga gtagccaaca tatcatcgtg gaagatgaag
    16321 agtcggcaac caaggcgatt gatttactca aacgaaacag atctggtcgt gcaaccttcc
    16381 ttcctttgac cactatcaag gctcgtacga tttctagtca gaaccaagat actattgctg
    16441 caagtccagg atttctgggc atggcagatg agctggttac tttcgatact agactggaag
    16501 ccattttcaa gaatttgcta gctacaacgg ccatttttga taccgtggag catgcgcgtg
    16561 cagcagcgcg ccaggttcgt tatcaggttc gtatggtgac attggacgga acagagctgc
    16621 gcacaggtgg ttcttatgca ggtggagcta atcgccagaa taacagtatt ttcatcaagc
    16681 cagaactgga gcaattacaa aaagaaattg ctgaagaaga agcaagtttg cgttcagatg
    16741 aagtgagttt gaagaacttg caagatgagc tagctagatt gacagaaaga ttagaagcca
    16801 tcaaatctca gggagagcag gctcgtattc aggagcaagg cttgtccctc gcctatcagc
    16861 agaccagtca gcaagttgaa gagctagaaa ctctttggaa actccaagaa gaggaattaa
    16921 atcgtctttc tgagggagaa tggcaagcgg ataaggaaaa atgccaagag cgccttacta
    16981 caatcactag tgaaaagaat aatctggaag ctgagattga agagattaag tctaataaaa
    17041 acgccatcca agaacgttat caaaacttgc aggaagagct agctcaagct cgtctactta
    17101 agacagaact gcaagggcaa aaacgttatg aagttgctga tattgaacgc ttaggtaagg
    17161 aactagataa tcttgatatt gagcaagaag aaattcagcg ccttcttcaa gaaaaggttg
    17221 acaatcttga gaaagttgat acggatttgc tcagtcaaca ggctgatgaa gccaaaactc
    17281 aaaaaacaaa tctccaacaa ggtttgattc gcaagcagtt tgagttggat gatattgagg
    17341 gtcaactgga tgatattgct agtcatttgg atcaggctcg ccagcagaat gaagagtgga
    17401 ttcgcaagca aactcgtgct gaagccaaga aagaaaaggt tagcgagcgc ttgcgccatc
    17461 tacaaagtca attaacagac cagtaccaga tcagctacac agaagcttta gaaaaggcgc
    17521 atgagttgga aaatctcaat ctggcagagc aagaagttaa ggatttagag aaggctatac
    17581 gctcactggg tcctgtcaat ttagacgcta ttgaacagta cgaagaagtt cacaaccgtc
    17641 tggatttcct aaatagccaa cgtgatgata ttttgtctgc gaaaaacctg ctccttgaga
    17701 ccattacaga gatgaatgat gaggtcaagg aacgctttaa atcaaccttt gaggtcattc
    17761 gtgagtcctt taaagtgacc ttcaagcaga tgtttggtgg aggtcaggct gacctcattt
    17821 tgactgaagg agacttgctg acagctgggg ttgaaatttc tgtccaacca ccaggcaaga
    17881 aaatccagtc tcttaatctc atgagtggtg gtgaaaaagc cctatcggct cttgccttgc
    17941 tcttctccat tattcgtgtc aagactattc catttgttat cttggatgag gtggaagctg
    18001 cgctggatga agccaatgtt aaacgttttg gggattacct caaccgcttt gacaaggaca
    18061 gccagttcat cgtcgtaacc caccgtaagg gaaccatggc agcggctgat tccatctatg
    18121 gagtgaccat gcaagaatcg ggtgtttcaa agattgtttc agttaagtta aaagatttag
    18181 aaagtattga aggatgacaa ttaaactagt agcaacggat atggacggaa ccttcctaga
    18241 tgggaatgga cgctttgata tggatcgtct caagtctctc ttggtttcct acaaggaaaa
    18301 agggatttac tttgcggtag cttcgggtcg gggatttctg tctctagaaa aattatttgc
    18361 tggtgttcgt gatgacatta ttttcatcgc ggaaaatggc agtttggtag agtatcaagg
    18421 tcaggacttg tatgaagcga ctatgtctcg tgacttttat ctggcaactt ttgaaaagct
    18481 gaaaacttca ccttatgtag atatcaataa actgctcttg acgggtaaga agggttcata
    18541 tgttctagat acggttgatg agacctattt gaaagtgagt cagcactata atgaaaatat
    18601 ccaaaaagta gcgagtttgg aagatatcac agatgacatt ttcaaattta caaccaactt
    18661 cacagaagaa acgctggaag atggggaggc ttgggtaaac gaaaacgttc ctggtgttaa
    18721 ggccatgaca actggctttg aatccattga tattgttctg gactatgtcg ataagggagt
    18781 ggccattgtt gaattagtta aaaaacttgg tatcacaatg gatcaggtca tggcttttgg
    18841 agacaatctt aatgacttac atatgatgca ggttgtggga catcctgtag ctcctgaaaa
    18901 tgcacgacct gaaattttag aattagcaaa gactgtgatt ggtcaccata aggaacggtc
    18961 ggttatagct tatatggagg gcttataatg gcagatataa aattgattgc attggacttg
    19021 gacgggacct tgctgactac tgataaaagg ctgacggatc gtaccaagga aaccttgcaa
    19081 gctgcgcgtg atcgtggtat caaggtcgta ttgacaactg gtcgtccctt aaaagccatg
    19141 gatttctttc tccatgagtt agggactgac ggtcaggaag atgagtatac cattactttt
    19201 aatggtggat tagttcagaa aaatacagga gaaatccttg ataaaacagt cttttcatat
    19261 gatgatgtgg cacgtttgta tgaagaaaca gagaaattat cactgcctct tgatgccatc
    19321 tcagaaggaa cagtttatca aatccaatcg gaccaagaaa gtctttatgc caaattcaat
    19381 ccagctttga cctttgttcc agtggacttt gaagacttat ctagtcaaat gacctacaac
    19441 aaatgcgtga ctgcctttgc tcaagaaccc ttggatgcag ccattcagaa gatttctcca
    19501 gaattgtttg accaatatga aatctttaaa tcacgtgaaa tgttgctaga atggtcacca
    19561 aagaatgttc ataaagcaac aggtttggca aaactaatca gccatcttgg aatcgaccaa
    19621 agtcaagtga tggcttgtgg tgacgaggcc aatgacctct ctatgattga atgggcaggt
    19681 cttggtgttg ctatgcaaaa cgctgttcct gaagtaaagg cagccgcaaa tgtagtgacg
    19741 ccgatgacca acgatgagga agctgtcgcc tgggctatcg aagaatatgt gctaaaggag
    19801 aactaagata tgggattgtt tgaccgtcta ttcggaaaaa aagaagaacc taaaatcgaa
    19861 gaagttgtaa aagaagctct ggaaaatctt gatttgtctg aagatgttga tcctaccttc
    19921 acagaagttg aggaagtttc tcaggaagaa gcagaggttg aaattgttga acaagctgtg
    19981 ttccaagaag aggaaatcca agacacagtt gaagaaagtc aggattcaga gccagctgta
    20041 ggggtttctc aagaagaaat agaagaatta ccaaactcag aagaattacc agaggaagag
    20101 aagcttgagc acgaaggaac tgtagaagaa aataattctg aagtgcttga accagaagct
    20161 cctcaaacag aagaaactgt tcaggaaaaa tatgaccgca gtcttaagaa aactcgcaca
    20221 ggtttcggtg cccgcttgaa tgccttcttt gctaacttcc gctctgttga cgaagaattt
    20281 ttcgaggaac tggaagaact gctgattatg agtgatgttg gtgtccaagt cgcttctaac
    20341 ttaacggagg aactacgtta cgaagccaag cttgaaaatg ccaagaaacc tgatgtactt
    20401 cgtcgtgtca tcattgagaa attggttgag ctttatgaaa aggatggtag ctacgatgaa
    20461 agcatccact tccaagataa cttgacagtt atgctctttg ttggtgtgaa tggtgttggg
    20521 aaaacaactt ctatcggaaa actagcccac cgctacaaac aagctggtaa gaaggtcatg
    20581 ctggttgcag cagatacctt ccgtgcgggt gcagtagctc agctagctga atggggccga
    20641 cgagtagatg ttccagtagt aactggacct gaaaaagctg atccagccag cgtggtcttt
    20701 gatggtatgg aacgtgccgt gactgaaggt atcgatattc tcatgattga tactgctggt
    20761 cgtctgcaaa ataaggataa ccttatggct gagttggaaa agattggtcg tattatcaaa
    20821 cgtgttgtgc cagaagcacc acatgaaacc ttcttggcac ttgatgcatc aacaggtcaa
    20881 aatgccctag tacaggccaa agaattttcg aaaatcacac ctttaacggg aattgttttg
    20941 actaagattg atggaactgc tcgaggaggt gtggttctag ccattcgtga agaactcaat
    21001 attcctgtaa aattgattgg ttttggtgaa aaaatcgatg atattggaga gtttaactca
    21061 gaaaacttta tgaaaggtct cttggaaggt ttaatctaat cagaagcaa
//
LOCUS       DAYYYC010000035        20988 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.035, whole genome shotgun sequence.
ACCESSION   DAYYYC010000035 DAYYYC010000000
VERSION     DAYYYC010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20988
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.035"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(1..516)
                     /locus_tag="ACHBV5_001406"
                     /pseudo
     CDS             complement(1..516)
                     /locus_tag="ACHBV5_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            complement(890..1039)
                     /locus_tag="ACHBV5_001407"
     CDS             complement(890..1039)
                     /locus_tag="ACHBV5_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HFM9967185.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFCKLQNYTSVNIFSKDIF
                     EAIVN"
     gene            1004..1123
                     /locus_tag="ACHBV5_001408"
     CDS             1004..1123
                     /locus_tag="ACHBV5_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HFM9967186.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(1219..2565)
                     /gene="glnA"
                     /locus_tag="ACHBV5_001409"
     CDS             complement(1219..2565)
                     /gene="glnA"
                     /locus_tag="ACHBV5_001409"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFM9967187.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2602..2958)
                     /gene="glnR"
                     /locus_tag="ACHBV5_001410"
     CDS             complement(2602..2958)
                     /gene="glnR"
                     /locus_tag="ACHBV5_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HFM9967188.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(3035..3562)
                     /locus_tag="ACHBV5_001411"
     CDS             complement(3035..3562)
                     /locus_tag="ACHBV5_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFM9967189.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRVRLFLEKKEK"
     gene            complement(3698..4894)
                     /gene="pgk"
                     /locus_tag="ACHBV5_001412"
     CDS             complement(3698..4894)
                     /gene="pgk"
                     /locus_tag="ACHBV5_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFM9967190.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(4984..9963)
                     /locus_tag="ACHBV5_001413"
     CDS             complement(4984..9963)
                     /locus_tag="ACHBV5_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HFM9967191.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFADEGVEISGYDAQK
                     TGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELTFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPTSDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            10256..11887
                     /locus_tag="ACHBV5_001414"
     CDS             10256..11887
                     /locus_tag="ACHBV5_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HFM9967192.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGIGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNIIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(12428..14035)
                     /locus_tag="ACHBV5_001415"
     CDS             complement(12428..14035)
                     /locus_tag="ACHBV5_001415"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFM9967193.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENRN"
     gene            complement(14425..15012)
                     /gene="rpoE"
                     /locus_tag="ACHBV5_001416"
     CDS             complement(14425..15012)
                     /gene="rpoE"
                     /locus_tag="ACHBV5_001416"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFM9967194.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(15140..15589)
                     /locus_tag="ACHBV5_001417"
     CDS             complement(15140..15589)
                     /locus_tag="ACHBV5_001417"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9967195.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(15594..15983)
                     /locus_tag="ACHBV5_001418"
     CDS             complement(15594..15983)
                     /locus_tag="ACHBV5_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HFM9967196.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(16011..16661)
                     /locus_tag="ACHBV5_001419"
     CDS             complement(16011..16661)
                     /locus_tag="ACHBV5_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFM9967197.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIR
                     GDLPDYLTILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKNPVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVFASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(16651..17214)
                     /locus_tag="ACHBV5_001420"
     CDS             complement(16651..17214)
                     /locus_tag="ACHBV5_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFM9967198.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(17379..17528)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(17588..18091)
                     /locus_tag="ACHBV5_001421"
     CDS             complement(17588..18091)
                     /locus_tag="ACHBV5_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HFM9967199.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(18284..19114)
                     /locus_tag="ACHBV5_001422"
     CDS             complement(18284..19114)
                     /locus_tag="ACHBV5_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFM9967200.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRLLV
                     LIAIFSVFLLYLSEIHFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGAYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(19099..20781)
                     /locus_tag="ACHBV5_001423"
     CDS             complement(19099..20781)
                     /locus_tag="ACHBV5_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9967201.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHCPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLRTELVKETPELQSLFRLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKALSSFIQTEGRYLWEGQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEQEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQQGHTIVMITHDMQLMLDYSDRALVMVDGELIA
                     DTDPASLLSNPELLVKANLKETSIFNLAKKLDVDPLALTAFYKERREGCKLN"
BASE COUNT         6075 a         4632 c         3849 g         6432 t
ORIGIN      
        1 tattcgttgt tgttcggata gtggggggag agcaattaat aatagattaa aattataatc
       61 attgattgca ggataacttg ttccagtaga tttattatta acacgattga taaaattatc
      121 tgataataaa taatatttca aatatgtttc gttaagtaaa gtatccaaaa caataaatgc
      181 tgtactagct atcaaatact ctttaagttc tctaactaca gcaatatttt ttagatatgg
      241 tctaactgtt gaaaataaga cactattctg cgaaactaat tttctagcac gggaaggcgc
      301 ttgttcaggt gaaagatatt gtagattttt gtagttgatt atgttctttt ttctatcaat
      361 actagacgta tctatatacc taaaggattt ctctggctta ttttgcccaa aattccaata
      421 aattgatttt atcctcaccc actcccaagt atcaggaata tcataaggaa catcaatttc
      481 ttgagtactt ccatcagcaa acttcccata atgtttctta tgtgcttcaa gtatataaaa
      541 aggcgtaaaa atacgcctat agataatggg gttgaaatag gtttattgtt gatgagattg
      601 tagataattc aattttttac ttccaatcga atattcaaaa cctccacctt ttctgcctgt
      661 aattgttcat cataaaattc aatatcttca ggattttccc cttggcaacc tcggcagaaa
      721 tattcttccg ctcgatcagg attcaaaaat cgacaagcac aaacaaaaca gtcgccatca
      781 tcatttattg agataatata gtagattgaa ataagatgta aacaaatcga ttaggaaagt
      841 taaattagtt tctagaaatt tttagcagat gtagtgtacc attctagtct caatttacta
      901 tggcttcaaa tatatctttc gaaaaaatat ttacagatgt gtaattttga agcttgcaaa
      961 agttagtaaa cttgtagatt tcgatttgaa gtaacttgtt ttcttgcccg atattgtttt
     1021 tgaaattgaa tttttccata gtgactcctt aattttcttc tacacgtctg atgataaatc
     1081 taattcgcaa aagagtcaag aggatttttc gaaaaataaa tagcgaccga aatcgctatt
     1141 ttaagggtta taggtatttg atggcttaga ctgctgtgtg actgtttacc cacaggcaat
     1201 ctttcttcta tattagtatt agtaaaggtc taaataatta tcaatttccc attgtgaaac
     1261 gaaggttgca taacttgccc attcgattcg tttggcttca aggaagctag tgtagatgtg
     1321 atctccgaga gcagctttaa ccacttcatc ttctgtcaaa gctttcaaag cgttgtgaag
     1381 agttgatgga aggtctgtaa taccagcttc cttgcgctct tctgctgtca tgatgtagat
     1441 attttcttcg ataggagctg gtgcttcgat tttattttca ataccataca aaccaacttc
     1501 caaaagaaca gccatagcaa tgtaagggtt cgccattgga tccactgaac gcaactcaag
     1561 acgagttccc ataccacgtg aagcaggtac gcgcacaagt ggcgaacggt tacgaccagc
     1621 ccaagcaatg taaacaggcg cttcataacc tggaaccaaa cgtttgtatg agttaactgt
     1681 tgggttcatg atggcagtat agttgtaagc atgcttgatc aaaccgccta ggaaatggta
     1741 agctgtttct gacaactgca ttccttttgg atcatttgga tcaaagaagg cgttatttcc
     1801 ttctgcatca aacaaggaca tattacagtg catacctgag ccagcaatac caaattttgg
     1861 cttcgccata aatgttgcgt aaagtccgtg tttgcgagca atggttttaa caacaagttt
     1921 aaagatttga atcttatcac aagcacggag aacttcatcg tacttaaagt caatctcatg
     1981 ctgtccaacc gcaacctcgt ggtgactcgc ttctacttca aatcccattt tggtcaagac
     2041 attcacaatc tcacgacgtg tgttgtccgc aaggtcagta ggtgccaaat caaagtagcc
     2101 acccttgtca ttcacttcaa gtgttgggtc cccattttca tccaacttaa ataggaagaa
     2161 ttctggctct ggaccaaggt tgaaggattt gaatccaact tcttccatgt gacgaagagc
     2221 tcgtttcaaa ttaccacgag ggtcacccgc aaatggttca ccttctgttg tatagacatc
     2281 acagatcaga cctgcaacac ttccattttc atctccccaa gggaagactg tccatgtatc
     2341 caagtccggg tacaagtaca tatccgactc attgatacgt acaaaacctt caatagaaga
     2401 tccatcaaac ataaccttgt tcgacaaaac cttatctaac tgttcatctg tagcaggaat
     2461 ttcgacgttt ttcatggttc ccaaaatatc tgagaacata agacgaataa aggtaacatt
     2521 tttttccttg acttcacgac gaatatctgc agctgtgatt ggcataagtt ttctccttaa
     2581 tctatgacta cttgcggttg cctaaccgcg accaaaaggt gactgtactg aagcaaaacg
     2641 cccctgttgg aggagttcat tgtgaagtgc acgacgtact tcagtctgac taaccgcttt
     2701 cttggatttc gcttcacgtt cagcatattt tttcttaatg gcagcgatat tataaccttc
     2761 agagatataa tctttgattt caagcagacg atccatgtca ttcaaggaat acatgcgacg
     2821 atttccttcg tttcgatcgg gcttgatcaa ctcttgatct tcataataac gaatctgacg
     2881 cgccgataga tcggtcaact tcataacact gccgatagga aaaacagcca tatttcggcg
     2941 aaattctttt tccttcattt acaatttcct tctttctgtc tattatagtc taaaaaaaga
     3001 caaacgtcaa ttgataatgt tataaaatgt aacattattt ttcttttttc tctaaaaaga
     3061 gacgaacacg atcaatatcg taatttacga taattgcgac aaaaactccc ataaacgttt
     3121 ctgatacacg cacaaacacg tacgaaattg tctcaccact tggaattgat agggtaatga
     3181 ttaacatagc tgctacacca ccaataaccc ctgctttgtt attcatggct acatttgtca
     3241 taatggttaa catggtgcag attggaacaa ctaccaaggt cacccaaaag gcttcgtgga
     3301 aaaaggtatt taataagaag aagaccaagg catagagtcc accgatacta tttcctagaa
     3361 tacgcgaagt cccaaaatga acactctcat caaaactctc cctcaggcta aaaacggctg
     3421 tcaaagcacc aatttgaaga cctttccagc caaaaaagcc aaaaatcaag agaactagaa
     3481 aaacagcaat acctgtttta aaggttcgca taccaagttt gaactgggat ttatcgaatt
     3541 tatatttttt aaaataactc ataatctcaa ctttctattt ccattttatc ataaatcggt
     3601 gatttttatg agtaatagtt gagaggaagc gtttttattt taagcaaaag aaaagaggaa
     3661 ctttcatccc tctcttcttt gatttgttta taaaatctta tttttctgtc agggctgcaa
     3721 gtcctggaag aaccttacct tcaagaagtt ccattgatgc tccaccaccc gtactaatcc
     3781 atgagaactt gtctgcacgg ccaaggttaa tcgctgcggc agctgagtca ccaccaccga
     3841 tgattgattt aactcctggt tgtttcacga tagcgtccat cacaccgatt gtaccagctt
     3901 ggaaatctgg gttttcaaat acacccatag gtccgttcca tacaactgtt ttggcaccag
     3961 tcaaagcttc gtcaaatttg gcgatagatt ttggaccgat gtcaagacca aggaagcctt
     4021 cagaaactgc ttcaccttca gtgtcacgca cttcagtgta accagcaaat gcgttagctt
     4081 cttttgagtc aactggcaag atcaatttac catttgcttt ttcaagaaga gctttcgcaa
     4141 catccaattt gtcttcttct acaagtgagt taccgatttc gataccttgt gctttgtaga
     4201 atgtgtaagt catcccacca ccgataagga ctttatcagc tttttcaagc aagttttcga
     4261 taacaccgat cttgtctgaa acttttgaac caccaaggat agccacgaat ggacgttctg
     4321 gagtttcaac tgcttcttgg atgtaggcaa tttcgttttc aagaaggaaa ccagcaactg
     4381 ctttttcaac gtttgctgag ataccaacgt tagatgcgtg tgcacggtga gctgtaccga
     4441 atgcatcgtt tacgaagata ccatctccaa gtgatgccca gtatttacca agttcaggat
     4501 cgtttttaga ttctttcttg ccgtcaacat cttcgtaacg agtgttttca accaagagaa
     4561 cttgtccatc ttcaagagcg ttgattgccg cttccaattc agcaccacga gtgacacctg
     4621 ggaaaacaac atcttgacca agttttgctg ccaagtcagc tgctacagga gcaagtgatt
     4681 taccagcttt atcagcttct tctttcacac gtccaaggtg agagaaaaga attgcacgtc
     4741 caccttgttc gatgatgtac ttaatagttg gaagagctgc tgtgatacgg ttatcgttag
     4801 tgattacgcc atctttcaat ggtacgttga agtcaacacg aacgaggact tttttacctt
     4861 tcaagtcaac gtctttaaca gtaagttttg ccatgttaca aaaactcctt tatttatttt
     4921 attcgaaact attatatcac actttggaaa tataaggaaa gatttcacaa gatttttcga
     4981 tatttaatct ttatcttctc ttttccgtct caaggtcaag gctaaactag caagaccgag
     5041 gctggctaag cctgctatta gggcttcatt agcatcagct gttcctgtat ttggcaattg
     5101 tttgcttgct tcttctgatt taactgctgt attttgagct ggtttttcct gtgtagctac
     5161 tactgctggt actgttttta cttttgttcc aatttcaaca atttctggaa tcgcttcttg
     5221 gatgacttct gttgaacgaa gacgacgctg accgttttca tcaacttcaa agacatgtct
     5281 taacagtcca tctcgtccct gtatgatgac tcgttgttcc ccaactagca tctcagcatt
     5341 ttcatgctct tgacgatgaa aggcaacctt ttcctcttga acttccaatt taggagcctt
     5401 ttgttgatca gaagtcggtt gataagtagg ttttggaagg actttgtttt gtggtgctgg
     5461 tttagcaggt tgtggttttt cagcagattc ataaacaaag gcataatgag taaagtgtgg
     5521 tgctgtaaag ataacatgac tatccgtttg ttcaaaagtc aattctactg cctctttgcc
     5581 ttcaggtaag aaaaatactt tcttaacttt cttatctttt tcaattggga ttttcacaat
     5641 agaagcgtaa gagagatcaa catcttgacc tttttcatcc aaaccttcta tttcaaagac
     5701 atgagcatct tctccagcaa agtatttctt ctcttcagca cttgcttgaa cacgctctac
     5761 tttcaaaccc ttgatgacag tcttctcttt atttgagaag tgtacttcaa cacctgtttt
     5821 actatcagaa aagactgctg gcttgtcttc tttcaataaa gcaaccagat cttttagact
     5881 ctgtttcgct gttgtaagct cttctggact caaatctact ttttcaacca aggccttgtt
     5941 tttctcaaga agcggagcta gggcagaacc tgaaggatgg tttggtttgg cagccaagag
     6001 ttcttgaacc tcacctgtta agcgatcaag ctctgtcttt tcttccgtaa atttctcttg
     6061 accattcaga gctttatgag cttctgtcaa tttattaagt cggtcattga cttgatcttg
     6121 ggtgctagtt tcatggtctt tcaacacttg ttcggccgct tcaattgctt tcaagaaggc
     6181 ttcttttact tctgatgaag caaagttata gaccaccttg ttcttagcag cttcaacttc
     6241 tgctaatttt tgtttgaggt actcatcgtt caatgctgct tttggagata ccaaaacatc
     6301 aaagctaact tcatggcctt ggtaatgaag cgtcaaggtt tgacgaccag tcttttgagc
     6361 atcgtaacca gaaatttcaa ctccctcatc agcaaaggaa tgttcttcca tggtgtcatt
     6421 gctataagcc actgcaaagc gtccttcaga caagtctaag ctatcaccaa ctaggtaatc
     6481 ttttttcggt tcctgactta cttcaattcc caaaatagtt ttcggacttg cttcgtcttg
     6541 gccagtgaca gtcactgaca aattagcatt taccggttgt cccaaatatt ggagagtaag
     6601 attctgttct cccttatgat gcgtatcaaa acctgatact gatacacctg cgtgagttag
     6661 gcgaatgagt tcgtcctcag ttcctccttc atactgaact cgaagaacac cacctctaag
     6721 gtccaaatcc tccccttcgg cgtagcttgt tttcttaggt cctgtttcta ggctgactga
     6781 cttgattctt ctgtcatctt ttggaacgga aactgctagg acattactaa tttccttgcc
     6841 tggcaactgg gtacgataat aaagaagacc agattgattt gtcaaatcca atggtgcact
     6901 tgctaggtct cctccaactt cgctcttcaa ggttgcgagc ggagtttgag aatttggatt
     6961 atcataaacg gtaatagttg ctccagccgg tacatctgca aagccaactt gtaccttgtt
     7021 attgcctaga gaacgggctg cagccttggc catcggaata ttgacactct cagtatcaag
     7081 cttttcatac attttccagt tatagatacg aatagccttc catggagttc cattgtcaga
     7141 agtgacaaca ttcaagcgcc agtcttgagc agtgattggt ttatcaagag tgatatctgt
     7201 cacgtgtgct ttgttaccac ggacttcctt agctagcttc cactcaccat ctgcatcttt
     7261 ataataaagg tcaaagtctt tagtgttcat caagccatcg ttaacagact caccaccagc
     7321 tcctgcatga tccatgaccc atctaacaac ggtacgtggc ttggtcaaac gaatatccac
     7381 actaccactc aactgagctg aagaccattt atctgacaag ctagtaatgg taccgttcaa
     7441 cataccttca ataccttctc caccttcagt cttagggaaa gtactatcaa taactgttgc
     7501 acctggaacg atattttcag ctagtggttt tggtaggctg gtatctttta cagtcatacc
     7561 ccaatcaaag gttgtggttg cagcttctga acgaactcca tttttaccga ctgctacaac
     7621 cttcagttct tgagttgtac cctgagcact tgctgagcgg ctaacttttg gtagataaat
     7681 agttgtagaa gatgagccag ttagtaattt ccagctgtct ccatcttttt cataaacttc
     7741 atagaaatct gcatccttgt tgcctttaaa ttgcacaact gcttccgctt cttgggcatt
     7801 tttaagagat tgtttcacta cagaaaagct tgtcggcgat tgtggctctt ggtgattgtc
     7861 cgagatagtt aattgtccta ggttaaactg ataatctttt acagcacctt catgctcgaa
     7921 aaatagtttg actgcataga tggttttacc cgctagtgag ctaagatcaa attcttcatt
     7981 tgtccagttg tcagaaaggg ttagctcttt ccatgcatct gcatcatcga atttgtagtc
     8041 tggagttgta gagaatgcca tataaacttt agaacctttt cctcccttgt gggcaacacg
     8101 aagtttggtc ttctcagtta cttctaactt agtagaataa agtctcacat cctgatctgt
     8161 cttaccagct acatcaccag agaatttaag ggaatttccg ccattatagg catctgtaaa
     8221 atcatattct gcacgaagtt tttcccctgt tgaagtctgc caccagcgcc atgttggaag
     8281 aacacctgat actgaacgat aattccactc agaatcctta gaaaccttac catctacgaa
     8341 ccatttttta ccatgacctg tattaaaaga agtagtaaaa gtattaccta ccgctggcgt
     8401 acggtccgca actaggttag caataccata ccaatctttg tcacctggtt tttggccagt
     8461 ggggtctcct tgataacctg taaagaagat atcttcattt ttatgataat cttcaccagt
     8521 ttttcctaaa cttgtaatgg tatctggggc aaataaacca agagaaaggc gcaatttccc
     8581 attttcgtct aaaatgtcat tccacttaac ctttgtcttg taggaaccac cctgttgcaa
     8641 ttccaaacct gcaaatacat cataaggatt acgaccaatc cagttggcag ttgcaatagt
     8701 gtaatcattt ttagccttat cccagttaaa gttagcaaag aagttatctg ccggaacctt
     8761 atctccttct ggttgcatga attggtagtt gtattctccc aaaccatctt gatggtaacg
     8821 tccatagtta taggtcatgg catcatacca agaatacttg attggatggt ttaccttagc
     8881 agcatattcc ttgctataga gcataaactg gcgcatcttt tctccaagag gtttaaccaa
     8941 atctccagtt gtttcttggt tgatgaaata gccatcatag ccataatact ttgccatgtc
     9001 taccaattta cgggcaattg ggaagctacc atctgcgtct tgcttcaaag cttcagcaaa
     9061 tctttcttga tctgcaatac tattagacca gttgaagaag agtgtaccgt atacaggaac
     9121 cccgttacgg tgacctgcat caataacgtc aggagttggt acgagacctt cccagaagac
     9181 cattgaatct agatattgcc aatagtcaaa agcataggcc ttgaactctt ctccaccaac
     9241 agaagcatgg tcttttgctt tagaattggt gtttgataag gcttgaactt ttgcttcctt
     9301 gctagctttt tcattgacta aatgacctgt ccgacgtgaa gcgaggacaa cagatccgcg
     9361 gttaatagca tcgtcttcac gagcacctgg ttcccatttt aacaattctt cccaagaatt
     9421 aaatttgatt tcctttggtt ttaatgtttt ttctgtattt ttagggacat ctggctggac
     9481 ttctttttca gtcttattag cttctgctgc tggtttagac tcatcccctt ggttagttgc
     9541 ttcgggcttt gcttctgttt ccttgtcaga cttaggtttt gcttctgcag atggtgtttc
     9601 tgcaaccacc tcacttgctt tttcctctgg tttagctgcg ctagctgctt ctgcagtttc
     9661 agtagttgca gcttcattgc ttgctggcga agcagtttca gatgctatcg ctactccttc
     9721 tgccttttct agcttgtttt ctctagcatg ttccccttca ttctgcttat cagcttcatt
     9781 ggtcgaatgc tcactctctc ctgaaacaag ctctgtatta gctccgctat tttcaggaac
     9841 tgcagtttct tcagccaagg ctggaccagc aaataaaaca gcaccaatca tcagcgagca
     9901 ggctcctact gataacttac gaatactgta acgacaacgt ctttcaaaaa atggattctt
     9961 cattttctcc tcctaaaaga ttgattttgt tgttttcaag aaagcgcttt atattctgta
    10021 gttttttatc aaactctaga accatgataa tcacattttt atcctaaaac atttttagac
    10081 aaaaaacaat agctgctttc ataaatctaa aataaggtta aaaactctta aaaataatac
    10141 acttatcaat tataattttc ttttacaaac ttgacgttaa cacttgttag atttactttt
    10201 atcctttaaa atagaatagg agatattccg cgattatttt tcggaggaaa aagaaatgtc
    10261 cattaattgg caggaaattt tatttcactt tttaggtggt ctggggctat tcttatatag
    10321 catcaagacc atgggagacg gtttgcaaca agctgctgga gatcgccttc gtttttacat
    10381 tgacaaatat actagtaatc ctttctttgg agttctggtt ggtattggga tgactgctct
    10441 aattcagtct agttctggtg taacagttat tacagtcggc ctggtcagtg ccggtctctt
    10501 aaccttacgt caggctatcg ggattgtcat gggtgctaat attgggacaa ctgtcacatc
    10561 ctttctcatc ggttttaaat taggtaacta tgccctacct atgctcttta tcggtgccgt
    10621 ctgtctcttt tttacgaaaa atcggacagt caataatatc ggacgcatcc tctttggtat
    10681 cggtggtatc ttttttgccc tcaatctcat gagcggcgca atggctccac tcaaggattt
    10741 acaggtcttt aaggactata tgattgagct aagtaagaat cctgttttgg gtgtctttgt
    10801 cggtactggc ttgaccttgc taattcaagc ttcttcggct accattggga ttttacaaaa
    10861 cctctacgcc ggcaatctaa ttgacctaca gggagctttg ccagttctat ttggtgacaa
    10921 tatcgggaca accattacag ccatcattgc ctctttaggg gctaatattg cagctaaacg
    10981 ggtagcagga gctcatgttg ccttcaacat tatcggaaca gtcgtctgcg ttatttttct
    11041 agttcctttt actgtcctga ttcattggtt tgaagctacg ctaaatctag caccggaaat
    11101 gaccatcgcc tttgctcacg gaacctttaa tattaccaac accattgtcc aatttccatt
    11161 tatcggagct ctggcttact ttgtaaccaa gattattcct ggagaggacg aggttgtcaa
    11221 atacgaaccc ttatatcttg atgaacattt catcaaacag gccccatcta tcgctctagg
    11281 aaatgctaag aaagagctct tgcacttagg aaactacgct gctaaagcct ttgacctttc
    11341 ctataagtac atcattgact tggatgaaaa agttgctgaa aaagggcata aaaccgaaga
    11401 agcaattaac accatcgatg agcaattaac acgttatctc attgcccttt caagcgaagc
    11461 tctcagccaa aaagaaagtg aagtgcttac caatatcctt gattcctccc gtgatttgga
    11521 acggattgga gaccacacgg aggctctact caatctgact gactatcttc aacggaaaaa
    11581 tgttgaattt tctgatgccg ccttgaaaga attagaggaa gtttaccgcc aaactagtga
    11641 ctttatcaaa gatgctctgg atagtgtgga aaacaatgat attgaaaaag cacgcagtct
    11701 tgtagaacgt catgaagcaa tcaataagat agaacgtgtt ctcagaaaaa cccacatcaa
    11761 acgcctcaac aaaggcgaat gttcaacaca agctggggtc aactttatcg acatcatctc
    11821 acactacact cgtgtatcag accacgctat gaaccttgct gaaaaggttt ttgcagaaca
    11881 aatctaataa ccaagaagct atccatcata attggatggc ttcttacttt ttcctaagca
    11941 agactaggct gaatgaaact gaaagagtat tctgcagata tatagtatat tgaaactaga
    12001 atagtacacc tctatttcta aaacattgtt agaaatcgat ttgtcctgtt attatttcat
    12061 tttactataa tggattaaat taaaaaagta tagtgtattg aatctataac agtccatctt
    12121 gactgctaaa atatttctat aaattaattt gacttttctg atagagatgt tcacatctta
    12181 tttcaattca tgatacaatc cagttcctaa aactttgcta gaaattaatt tggctttccg
    12241 aattaatttg ttcagatttt atttcatttc aatatactga taaatccatt cactagcaca
    12301 gggcaagagg gagtcgctat tgatttcaac ggtagcaggt acatacagag gactcctacc
    12361 tcagatatac tgcaatatca tcgtgtgcaa aaaacctctg agatttttct caaaggttct
    12421 gattttgcta atttctgttc tcaaccgctg cagtaacaaa ggcagtgtag agttcttctg
    12481 gtcggtttgg acggcttgac agttcagggt gatactgaca agctacaaag aatttatttt
    12541 caggaatttc cacgatttct accaaacgat tgtctggaga aactcctgaa aagacaaagc
    12601 ctgctgcctc aaactgctca cggaaggcgt tattaaactc ataacggtga cggtgacggc
    12661 gttgcaccac ttcttgattg tgataagcag cagcagcctt agagccacgt ttcaacttag
    12721 acggataaag tcccaaacga agggttccac ccatatcctc aatatcaatc tgatcacgca
    12781 tgatatcaat gatagggtat tttgtttctg gtgcaagctc tgcagaattg gcaccttcaa
    12841 gacctaaaac gtgacgagca aactcgatac atgtcaactg cattcccaag cagactccca
    12901 acattggaac atcattttca cgcgcatagc ggatggcttg gattttccct tctgtaccac
    12961 gttgaccaaa accacctggt acgatgatcc cgtctgcatc agacaagagt tctgctacat
    13021 tctctgctgt cacatcattg gcattgaccc aattgatttt aacttctgca tcattgacat
    13081 agccagagtg tttcaaggct tcgaccactg agatataggc atcttgcaac tccacatact
    13141 taccaacaag ggaaatctta acttgtttct tgaggttcat gaccttgtcc accatggctg
    13201 accattctgt catatccgct gctggtgcgt ctaatttcaa atgatcacaa acaatttggt
    13261 ccatcccttg tgcctgcaag ttcagtggaa tttggtaaag atgttcaaca tccaacgatt
    13321 cgataacggc ttctggtgcc acatcacaga actgggccag tttattttta attccttgac
    13381 cagctggctc ttctgtacga ataaccaaca tatttggttg gattcccaag ccacgcaatt
    13441 ctttgacaga gtgttgggtt ggtttggttt tcatttcacc agcagccttg aggtaaggaa
    13501 gcaaggttgt atggatatac atgacattat ccgcacccac atctgccttc atctgacgaa
    13561 gagcctctag gaatggcaag gactcgatat ctcctactgt tccaccaacc tctgtgataa
    13621 tgacatcaga gtcggtcgtt agagcggcac gcttgatttt ttctttcaaa gcatctgtga
    13681 tatgaggaat gacttgaaca gttgccccaa ggtattctcc acggcgttct ttacgaagaa
    13741 cttcactgta aattttccca gttgtcacgt tggaatattt gttgagattg atatcgataa
    13801 aacgttcata gtgacccaag tccaaatctg tctcagctcc gtcatctgtc acaaaaactt
    13861 ccccgtgctg gtaaggactc atggttcccg gatcaatatt gatataaggg tcaaactttt
    13921 gaatggttac tttgagacca cgatttttca agagacggcc tagactcgct gccacaatcc
    13981 ctttcccaat ggacgatacc acaccaccag ttacaaaaat atatttcgta gacatagatt
    14041 cctctttcta aaatgctcaa ggtcttgtta actacgaggg gatatagaaa acaagaccct
    14101 actaataaga ataatctggg acgactgcac cagattcaca actaatactc ttcgaaaatc
    14161 tcttcaaacc gcgtcaacgt cgccttgccg tagatatgtg ttcctgactt tgtcagtctt
    14221 atctacaacc tcaaaacagt gttttgagca gcctacggct agtttcctag cttgctcttt
    14281 gattttcatt gagtataaaa tacaagaaga taacttcttg aaaaaacaaa aatagctccc
    14341 taagaactag ggagccccga cctctaaaag aggtgcccaa acaatatgat acctaaaaat
    14401 aggataattg tcaatagcta actcttattc ctcgctggtt tcagcgtcgt catctgaaaa
    14461 ctcgtcgtcg tcttcgttga gatccacatc ttctcccaag tcatctggag cgatttcgtt
    14521 gatttctgca tcataagctt ccacttcatt tttttcatca tctggatttt catcatcgta
    14581 tgaaagagct ggatctgctt cgtatgcatc ttcgtcttct ggatcatctg cattgtagtc
    14641 aatggcatct gaatcaccat ccataaaggc attgacacgt tttttcttag cttttggtgc
    14701 tacttcatcg tcgtcatttt cttcaagagc gatgatttct tcgtcgattt cgtccacacc
    14761 ataccatgaa cgaagacccc atttgttgtc cccaagtgag atgaagctac cgtcaaagtt
    14821 caactctgtg tagaacaaag gcaaagcttc gcggatatcg ctgtttgatg ttccaaggta
    14881 gttttgaatt tcgtttacaa gatcgctaaa atgcatctca tgatcgcgac cacgaagttc
    14941 caagatagca cgcgctacct caatcataga tagttcactt ttttcttgcc cagcaaatac
    15001 ttctaattcc aaagcgtttc tcctcattta tactactatc gccagagcga acagactctg
    15061 acctcatttt atcatttact ctttatttta cgataatttt gcggaatagt caaaggttaa
    15121 gggggagaaa gtggcaggat tagactaatt ccaatataaa actccttcct ttttctgttg
    15181 ctccattttc cacaaatcca agcgacttga aacacctcct agaagcatga ttgtaggtgt
    15241 agatttcctt gactctcaat tctttccatc cttttactcg agccaattca atcaaagcac
    15301 ttagaatctt ttttccaagt cctcgatgtt ggtaagcgga attcccaatc acaatgggga
    15361 gattatcctg agatagtgta atatccccaa ttggaaacca ttctcccttc tccttgactt
    15421 caatccaaaa aagctcacca tgccgatcca aataggaata catggcttcc aaggtcgctt
    15481 gactgtaagg aagcttcacc ccatctacga ggtaaaccaa gttcacatcc tgataccaag
    15541 caaaagcttc ctcacaatga ttgaccttat aataaggaac aaaacacaat gcactacctt
    15601 ttcaacaaaa gagttgctgc ttgattaaaa ccatcacacc agttatacca ttttgcttca
    15661 tacccatctt gagctaggat acgatcttct aaatcaaaaa cagagtaaat ctttctttcc
    15721 tcgcaagctt gcgcatagag atgatatagt tcatcaccac catctctatc ccactcagca
    15781 gaaatcgtat cccgacctgc caataaagcc tgataagccc tgtgatgccc atctgtaatc
    15841 agcaaacaat ctccaaaggc aagaatactg attggatcga cttggtttgt ttctgccgac
    15901 tggtaaagca tctgaatatc ttgcaacttc ttttctgata aatatagttg agtcggatga
    15961 agatctgcta tattgacttt catttctttc tcctcaaggg aattcgatac tcacttctgt
    16021 ttgcctttaa atcgccattg gaagcggagc ttgtcataga agggaaactc gataaacagg
    16081 actcccaagc ccacacagag actggcaaag acgtctgatg ggtaatgaac ccccagatag
    16141 actcttgata ccagcacact gactaggtag aggccaagga cgatttgtac gatttttctc
    16201 cagactggat ttttaattcg ttgactgaga atgacaatca gagtacctac catcaaagtt
    16261 acagccagag aatgtccact tgggaaggaa aatcccttct cttccaccag atgtaagata
    16321 gctggtcgtg ggcgctggta gatattttta aaggtcacga ttaaaagacc tgccaaagcc
    16381 agatttccca gcatgaagaa actttctatc ttccatcgct tacgataaaa gacaaaagct
    16441 gtaatgacaa cccaagtgat aatcactggg atatcaatca gacgtgtgag ggctcgaaaa
    16501 agaatagtca aataatctgg taagtctcct cgaatggcag tctgaatcga ttggtcaaaa
    16561 ttgaccaaca tttcagggta aaatttgacc atatagccaa gaataacgaa aagtaaaagg
    16621 gcaaaactgc ccttcattaa aaatgtttgt ttatctttca tagtgtttta aggttggttt
    16681 caaaaggacg tacaacaacc agaatgaaac ggaaaagatt acaccctcaa tcaagttaaa
    16741 aggtaatacc atggtcatta ggtagttgga aagtcccaaa atttttccaa tatcaaagtt
    16801 agcaaactta gcgtacaaag gaacagcata aacatagttg agaaccaaca tggccaaggt
    16861 taaaccaaca gttccagcta gagagcctag taggaaacga agggttgtcc gttccttttt
    16921 ccaaatcaaa gcaaatacga tgacaaaaac tcccaaagct acgatattca tcggcaaacc
    16981 aatgtaagta ttcactcctt ggctgttaag aagcaatttc aatagtgagc gaagcaagag
    17041 cactcctaga gcagcaggca aatccatgac caccagaccc acaaggactg gcaagatact
    17101 aaattcgatc ttgaggaaag atgccgctgg taaaagcgga aagtcaaagt acatcagcac
    17161 aaatgagatg gctgataaaa ttgcaatggt cgaaagtcga cgtgtgtttg tcataacagg
    17221 ttcctccaat tttctataaa atcagaagaa gttggaaagg attcctctat ctattctcac
    17281 tttttatatc ccaaaaattc cctcttactc tattaaagaa aaacaaagca agtggttaca
    17341 atccggctat aaatctatca aaacagacaa agctattctt tcgtcttctc ccatccagac
    17401 tatactgtcg gttgtggaat ctcaccacat cagcttgcgc tcgcggactt ctttaaagag
    17461 aaggaaaaga tcatttccta gttaaagtca ccgccggtcg ggaatcacac cctgccctga
    17521 agactctttt atcataacaa aaaacgcttg caagcgcaag cattttgttc attttcattt
    17581 tcatttttta tttcaattta tccacttcat aggtatggac gagctcaaga cctgcaaagt
    17641 tctgctggcg aagagcctca tagacaatca tgcagacggt attagacaca ttgagactgc
    17701 ggacatgttc atcattcatg ggaatacgga gagccttctc aggatgttct cgcataaaat
    17761 cttcaggtaa gcccttgtct tcacgtccaa agagaaaata atggtcctcg tcagtcgata
    17821 aatccacctc agaatagact ttttctgcga atttcgaaat cagatagagt tttcccttca
    17881 tctgagatat gaaatcttcc aaactctcgt aaaaataaat ctctagctta tcccagtaat
    17941 ccaatccagc ccgcttcatc ttgcggtcat caataggaaa gcccataggc ttgatgatgt
    18001 ggaggggaga attggtcgca gcgcaagtac gcgcgatatt gcctgtattt tgtggaattt
    18061 gaggttcaaa taatacaatg tgatttgtca tgacttgctt cctttcacca ttgcaaaaaa
    18121 atagccacac tgcccggagt caagctcagc aaacagcgtg gttaaggcat cgttaactta
    18181 cctcacaaca ggtttgaagt aaatcagcga aactactttc ttagtataac actttcagaa
    18241 tcattgtcaa tagaaatgac ttgatttttt caattttttc aagctatttc caagggttgt
    18301 aaaatcgtcc ctgattctgc aagataagta gtaaactaac tactaaaaac aaggttgcca
    18361 agagcaaggt aatatagtct ccttttttca aggcctgata actataccat gtgcgttttt
    18421 tctctttccc aaagcggcga agctccatgg cagtcgcaat ggtatcaatg cgttctagcg
    18481 agctaaaaat caagggagta ataatgagca gattgccttt gattcgttgc ataagagaag
    18541 ctttcttgga taattccatc ccacgcgctt cctgagacat cttgatggta aagaattctt
    18601 cctgcaaatc tggaatatag cgcaaggtta gactgacaga ataggcaatc ttgtaaggca
    18661 caccaatttg atttaaactg gaagcaaact gactagggtg ggttgtcatc aaaaagataa
    18721 tagccagagg aatagtgcaa aggtacttaa tagccaaatt tagcagataa aagagctctt
    18781 gactggtcag agtgtaggca ccgattccct gccaaatcac acttctctct ccgtaaagtc
    18841 caaccccata ctcgggagaa aagagataga ccatcaaaac gtttaaaacg gcaaataccg
    18901 tcgcaaaaac ggctacaaag gaaacatctt taaaatggat ttctgacaaa tagaggagaa
    18961 agaccgaaaa gatggcaatc agaacaagca gtctggtatc atagctaatc atggccgcca
    19021 atgacacgag aatgaaaaag aggagtttcc cagcgcctga caagcgatga atcacagtat
    19081 ctctatgctg gtaaccgatt aatttagctt gcatccttct ctcctttctt tgtaaaatgc
    19141 cgttaaagca agtggatcca cgtcgagttt cttagccaag ttgaagatag aagtctcttt
    19201 taggttggct tttactaaca gctcaggatt gctcaacaga ctagctggat cagtatcagc
    19261 aatcaattcc ccatccacca tgacaagggc tcgatctgaa taatccagca tcaattgcat
    19321 atcatgggta atcatgacaa tggtatgccc ttgttgatgc agttcttcga gaaattccat
    19381 aatctcagta tagttcttct ggtcttgacc cgcagtcggt tcatctagga ggataatttc
    19441 agcgcctaag accaaaattg aggcaatagt cacacgtttt ttctgaccaa atgacagggc
    19501 agaaatgggc caattacgga attcatagag accacagatt ttcaaggttt catagactct
    19561 cgtttcaatt tcctgctcgt ccacacctcg caaacggagt cccagagcca cctcatcaaa
    19621 aatcatattg gttgaaatca tttgattggg attttgcagc acatagccta ctcgttccgc
    19681 ccgctctgca acagaatctc cttttatatc ctgtccttcc caaagatagc ggccttcagt
    19741 ctggataaag ctactcaagg ccttggctag agttgacttc cctgctccat tttttccgac
    19801 aatggcaatc ttttcaccct ttttaatatc taaatgaaga gattttaaaa tcggtctatc
    19861 atcataagaa aacgacacgt cctctagtct aaagagtgac tgcaattctg gggtttcttt
    19921 taccagttcc gtccgcaact gaacctgacc ttttgagata gacaagttat ccagatctgc
    19981 taattgttct tccttgacta aatccacacc caattgacgg agagtggtga gataaagggg
    20041 ttcgcgaatt ccattttggg tcaacaaatc agtcgccagt aactggtcag ggctcccatt
    20101 aaaaaggata cgaccatcgt ttatcaagac aatccgatcc acagggcaat gcagaacatc
    20161 ctccaaacgg tgctcgataa taagggtcgt cgtcccctcc tccttatgaa tctggtcaat
    20221 caattcgata atatcctgac ctgacttggg atcaagattg gcgagtggct catcaaacaa
    20281 gagaatcgga ctttcatcaa tcaagacacc agccagactg actcgctgct tttgtccacc
    20341 tgacaaatcc tgagggcgct gatccagtaa aggaagaagg tccagctttt cagcccattt
    20401 ataaacacga cctttcatct catctagggc tgtcacatca ttttccagag caaacgccaa
    20461 atcttctgcc acagacaagc caataaactg cccatctgta tcctgcaaaa ctgtgctaac
    20521 cagatgagac ttatcataga tgctcatatc aaaggctgtt tgacccttta tcaaaaattc
    20581 tccatatgtc tgacccttgt aaatattggg aataatccca ttcaaacact gacccaaggt
    20641 agatttacct gatccagatg gtccaacaat taagactttc tctcccttgt aaatggtcaa
    20701 gtctatccct tgcaaggtcg gttcttgttg tgtttcatac cggaaagaga aatccttcca
    20761 ctcaattata gcttctttca tcttactctc ttcattcgct tcttagactt ctattttatc
    20821 ataaatcaag cccttcttgc agtctcttct cttaaaatct tagcgccaaa aagattccta
    20881 tcctagctta cttgcctaac taatctataa acatcgaaaa agactagttg cccagccttc
    20941 cccatcattt tatactcttc gaaaatctct tcaaaccacg tcagcttc
//
LOCUS       DAYYYC010000036        20745 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.036, whole genome shotgun sequence.
ACCESSION   DAYYYC010000036 DAYYYC010000000
VERSION     DAYYYC010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.036"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..431
                     /locus_tag="ACHBV5_001424"
     CDS             <1..431
                     /locus_tag="ACHBV5_001424"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HFM9967202.1"
                     /translation="DQMINQKQSKLGYKKFFKLLLSHPKDESLLFHCSMGKDRTGIAS
                     LFLLYILGVDMNDIFHDYLLSNKYLINVRKENIEYVNNHSGNVILMHNLLSLSSAKEE
                     YINRVLNVLDKEYGGILRYINTELGISSQEIEELKDRYLF"
     gene            1448..2440
                     /locus_tag="ACHBV5_001425"
                     /pseudo
     CDS             1448..2440
                     /locus_tag="ACHBV5_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            2442..3259
                     /locus_tag="ACHBV5_001426"
                     /pseudo
     CDS             2442..3259
                     /locus_tag="ACHBV5_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            3261..4046
                     /locus_tag="ACHBV5_001427"
     CDS             3261..4046
                     /locus_tag="ACHBV5_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9967203.1"
                     /translation="MKKYQRMHLIFIRQYLKQIMEYKADFLVGVVGVFLTQGLNMLFL
                     NILFQHIPLLDGWSFHQVAFIYGFSLIPKGIDHLFFDNLWALGQHLIRKGEFDKYLTR
                     PISPLFHILVETFQIDALGELLVGVLLLLMTITSLTWTWAKVFLFLISIPFATLIYTS
                     LKIVTASIAFWTKQSGAIIYIFYMFNDFAKYPIAIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLKDKDGLFNIGGLILISLIFFTLSLKLWNKGLDAYESAGS"
     gene            complement(4425..5620)
                     /locus_tag="ACHBV5_001428"
                     /pseudo
     CDS             complement(4425..5620)
                     /locus_tag="ACHBV5_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713014.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            6122..6325
                     /locus_tag="ACHBV5_001429"
     CDS             6122..6325
                     /locus_tag="ACHBV5_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM9967204.1"
                     /translation="MYIRLKNLREDKDLSQCQIAQYLHCSQSAYSRIESGKQDIPTSF
                     LKQLAKLYQVTTDYILEMDKFSC"
     gene            6456..6608
                     /locus_tag="ACHBV5_001430"
     CDS             6456..6608
                     /locus_tag="ACHBV5_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967205.1"
                     /translation="MTTNKDNDTSERSGCQRKRTAGEMPMNDLTSHTHGGNYTCYKEE
                     KVWNNQ"
     gene            6775..8568
                     /locus_tag="ACHBV5_001431"
     CDS             6775..8568
                     /locus_tag="ACHBV5_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM9967206.1"
                     /translation="MKKNNVEIIKADSLVRRRGDNVERHLKRVAAYCRVSSDSEDQKN
                     SYDSQVRHYKEYISQRSDWELADIYADEGISGTQVGKRQDFQRLINDCANGEIDYIVT
                     KAIARFARNTLDTLKYVRMLKDMQIGVYFEEENIDTLTMDGELLLTILSSVAQQEVEN
                     TSAHVKKGLKMKMQRGELVGFQGCLGYDYDVETKQISINKKEAKIVRYIFERYLEGIG
                     GKVIARELDELGYKSPRGLEHWNDTTVLGIIKNEKYKGDILMGKTFTVDPISKRRLSN
                     FGEEDKYYIKDNHEPIISKEDFEKAQEIRLRRAGNKKTAANVNGKRERYSKMYAFSSM
                     LECGFCGSILSRRSWHCRSDYRKVVWHCVTSIKKGKKFCKHSKGLEEIAIEGAFLEAY
                     RQVYHSNENLMTDLLETIESELNDNSLNKELKRITNKLRILLKKEENLVNLRLEGKVS
                     DSIYNEKYNEISSEKEFLAEEKVNIETTLKSEIDVKKRLTEFKHLLSSQKMLTEFDRA
                     VFESIVEKIIVGGVNSNGEIDPAMLTIIFKTGEIQNKDGKQFKSKRKNAKLETDKLCP
                     QNSDEDKKLYSQGTDNTRGVCSVAGSILASQ"
     gene            8652..9260
                     /locus_tag="ACHBV5_001432"
     CDS             8652..9260
                     /locus_tag="ACHBV5_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HFM9967207.1"
                     /translation="MKEQIFLMGGNPPIKKYSIVDKIVLSTKIKRIIIFTVFRENWEP
                     YMKKYTEVFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYINQEF
                     KSYIDHMLNKEAKIIGFSAGPLLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHY
                     DSWNDKANKDRAEELDNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            9542..9790
                     /locus_tag="ACHBV5_001433"
     CDS             9542..9790
                     /locus_tag="ACHBV5_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HFM9967208.1"
                     /translation="MCKPISIELCDDEVHSLHEWIDGRDAIDSILTYSENQQYTYGVE
                     AGKILRKIHTIPATEVCEDWEIFFNLKIDDKISNEMIW"
     gene            9895..10219
                     /locus_tag="ACHBV5_001434"
                     /pseudo
     CDS             9895..10219
                     /locus_tag="ACHBV5_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            10347..11576
                     /locus_tag="ACHBV5_001435"
     CDS             10347..11576
                     /locus_tag="ACHBV5_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFM9967209.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLMMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            11596..14292
                     /gene="ppc"
                     /locus_tag="ACHBV5_001436"
     CDS             11596..14292
                     /gene="ppc"
                     /locus_tag="ACHBV5_001436"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HFM9967210.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    14375..14592
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            14705..15709
                     /gene="trpX"
                     /locus_tag="ACHBV5_001437"
     CDS             14705..15709
                     /gene="trpX"
                     /locus_tag="ACHBV5_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM9967211.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPEFVLKEAGQVIE
                     "
     gene            15778..16644
                     /locus_tag="ACHBV5_001438"
     CDS             15778..16644
                     /locus_tag="ACHBV5_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9967212.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGHMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            16641..17399
                     /locus_tag="ACHBV5_001439"
     CDS             16641..17399
                     /locus_tag="ACHBV5_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9967213.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTISLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLFPRRLASYKDKFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRVIQDLKQEEKAKMKISDYYQLFE"
     gene            17489..19249
                     /gene="dnaG"
                     /locus_tag="ACHBV5_001440"
     CDS             17489..19249
                     /gene="dnaG"
                     /locus_tag="ACHBV5_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFM9967214.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPYQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRVGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VKEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            19252..20361
                     /gene="rpoD"
                     /locus_tag="ACHBV5_001441"
     CDS             19252..20361
                     /gene="rpoD"
                     /locus_tag="ACHBV5_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFM9967215.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            20375..20704
                     /locus_tag="ACHBV5_001442"
     CDS             20375..20704
                     /locus_tag="ACHBV5_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFM9967216.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
BASE COUNT         6632 a         3346 c         4324 g         6443 t
ORIGIN      
        1 atgatcaaat gatcaatcaa aaacagagta aacttggtta caagaaattc tttaaattat
       61 tactaagtca tccaaaagat gaatctcttt tgtttcattg ttcaatgggg aaggatcgaa
      121 caggaatagc tagcttgttc ttgctttata tattgggagt agatatgaac gatatttttc
      181 atgattactt actatctaac aagtatttaa taaatgtgag aaaagaaaat attgaatatg
      241 taaataacca tagtgggaat gtaatattga tgcataattt actttcactc agttcagcaa
      301 aagaagaata tattaatcga gtattgaatg tccttgataa agaatatgga ggaatactta
      361 gatatattaa tacagaacta ggaataagta gtcaagaaat tgaggaattg aaagatagat
      421 atctttttta gaatagtaag tactaaaaat gaatatataa cagtgcgaac ggcggttttg
      481 tttttgtcta attctactaa tttaacataa gcaaaaacgg attgttttct atgtaagtcc
      541 ttaactaaat tgatggaaag cacgttaaat tatgtgcaaa atgcgtacaa aatagtgttt
      601 atcaaatgta aaatttccta cttgtcatca aagttcaaca aatgtaggtt gtttggttat
      661 ttgggtagat ttctggactt atcgttggtt gtagagacat aatgttgcag ttaaagctta
      721 gagaataatc tccgtatttt tgttaggcaa tttaaaagtt aagacaaagt gagtttgtct
      781 cttaattcaa ctcaccacaa acacatcacc tttttattat aacttccgac caattttttt
      841 gaagagaaaa atgaaaaaac accaactgtg cagggtagct gacaaggctt ctagcttcca
      901 tttattgaaa ccaaatcaat ctgttatgag ataatagcag ttgcagaagc tgactacttt
      961 gagaagttaa atgaggttta ttatcaagaa tacttcatga atatagttat aagggagggg
     1021 gtagttgaaa gaattgactc atctgttaaa ataaaaatgg aaataataac atcataatag
     1081 tgtgacttag tatttttcag catcttggaa gtaggtaaat gatattaaaa ttatactgca
     1141 tagtaaagga tagtaatgag gaatttaata tcttcctgtc aatatcttca gttattaaag
     1201 tatttttata ttgggataac ttcgtttgct gaaatctata gtttatccaa ttataaattt
     1261 atatgttctt cgtcataatt ctttgtactt gagtaattta gcttacttac agataaaata
     1321 caagatggca tagttttagt agcttttttc atatggtttg taatgatggt aaattttctt
     1381 aactttactg tagtatgcta caatttttgt tgatattata acttgagtga aacgaaagga
     1441 gtgatttata aaaatgataa cagtagagca tcttcagaaa aattttgtga aaacaataaa
     1501 ggaacctggc ttaaagggag cttttcgctc tttttttcat cccaagagac aagtctttga
     1561 agctgttaaa gatttatcat ttgaggtgcc caaaggacaa attttaggct ttattggcgc
     1621 aaatggagcg gggaaatcaa caactatcaa gatgttgacg gggattttga aaccaacatc
     1681 aggtttttgt cgtatcaatg gaaagattcc tcaagagaac cgtcaaggct atgttaaaga
     1741 tattggtgta gtttttgggc agcgaactca actttggtgg gatttggctt tgtaggagac
     1801 ttactcggtt ttaaaggaaa tttatgatgt tcctgatgcg gtctttcaaa aacgcatgga
     1861 ttttctaaat gaagttttag atttgaagga atttattcaa gatcctgtca gaactctatc
     1921 tctaggtcaa cgtatgaggg cggatattgc ggcctcctta ttgcataatc cgaaagttct
     1981 tttcctagat gagcctacta ttggtttaga tgtttcggtc aaggataata ttcgacgtgc
     2041 cattacacag attaatcaag aagaagagac gaccatactt ttaacgaccc acgatttagg
     2101 tgatattgaa cagttatgtg atcgtatttt tatgattgat aagggccgag aaatctttga
     2161 tggaactgtg aatcaactga aaaagacttt cgggaagatg aagactctct cttttgaact
     2221 acatcctggg caggattata ttgtctctca ttttgaagga ctttctgata tctatgtgac
     2281 gagacaggaa ttgtcacttg atattcagta cgacagctcg cagtatcaaa cggctgacat
     2341 tattcaacaa actttgtctg attttacgat ccgtgattta aagatgacgg atgcgaatat
     2401 tgaagatatt attcgtcgct tctatcgaaa ggagctttag gatgactaaa ttatggaaac
     2461 gctataagcc ttttgttagc gctggaatcc aagaattaat cacgtatcgt gtcaattttt
     2521 ttctttatcg cattggggat gtgatggggg cctttgtagc attttacttg tggaaagctg
     2581 tgtttgattc atctcaccag tctctcattc aaggttttac tttatctgat atgaccttat
     2641 atatcatcat gagttttgtg acgaatctac tgacaaaatc agatagttct tttatgattg
     2701 gatgggaagt aaaggatggc tctattatta tgcgactgct tcgtccagtt cattttgcaa
     2761 tgtcttatct tttcacagaa attgggtcta gatggctagt ttttgttagt gttggtctac
     2821 catttgtaat tctgattgca ggtctaaagc tcttatcagg tgagtccttc ttacaaattg
     2881 ttttaataac cacagtttac cttcttagct taatcttagc ttttttgatt aatttttttt
     2941 caatatttgc tttggttttt cagcttttgt gtttaaaaac ttatggggat caaatctttt
     3001 gaaaaattct ttagttgcct ttttatctgg aagtttggtt cctctgacat tttttccaaa
     3061 aattattgcc gaactattat cttttttgcc attttcttct ttaatctata ccccggtgat
     3121 ggttattata gaaaagtata gcatgagtca aatgattcag gcgctctcgc tacaattatt
     3181 ctggctgttt attatgattg ccttatccca actgatttgg aagtgcgtac agaattatat
     3241 aactattcaa ggaggttaga atgaagaaat atcaacgcat gcacctgatt tttatccgac
     3301 aatatcttaa acagattatg gagtataagg ctgatttttt agttggtgtt gtgggtgtct
     3361 ttttgacaca agggttaaac atgctgtttc taaatatttt gtttcaacat attcccttac
     3421 ttgatggctg gagttttcat caggttgctt ttatttatgg tttttctctc attcctaagg
     3481 gaattgacca tctctttttt gataatctgt gggctttagg acaacattta attcgtaaag
     3541 gagaatttga taagtatttg actagaccca ttagcccttt gtttcatatt ttagtagaaa
     3601 cgtttcaaat tgatgctctt ggagaattgt tagtaggcgt cttattgctg ttaatgacaa
     3661 taactagtct tacttggact tgggcaaagg tttttctctt tttaatcagt attccctttg
     3721 caaccttaat ttatacctct ttaaaaattg taacagctag tattgctttt tggactaaac
     3781 aatctggggc aataatttat attttttaca tgtttaatga ttttgcaaaa tacccgattg
     3841 cgatttacca ttcgttttta cgttggttga ttagttttat cattcctttt gcttttacag
     3901 cctattaccc agctagctat ttcttgaaag acaaggatgg attgttcaat attggtggat
     3961 tgatccttat ctcattaata ttttttacct tatcattaaa attatggaac aaaggtttgg
     4021 atgcatatga gagcgcaggg tcttagaaga agtaaaatct aattaagaat tttgatagaa
     4081 cttcctattc tttggaagga agttttaatg atacattgag agctttgatt aggcttactg
     4141 tagtttttca aacaagaaat ttgaccattg tgcaaaaatg atacaaaggt atgtaatatt
     4201 tcagtcataa ccactcgttc atatcatgag tggtttttta gctcttttat acataccatt
     4261 tgttaaggga catacgatat tctagctcaa aaggttttct gaatgagtat caaaggaatg
     4321 tttagaagat aattgcgagc tgttttttga aatttgggca cacttaaaag acacttatct
     4381 ggtattaaaa aataaggtgt tacaatgata ggacatagat gactttaatg actttgggtt
     4441 aaagtgtagt cgtaaagttt gttatgcgtt atgaggtaat acattgtccg gatgaggcga
     4501 tgtatagaga caatcgtata tggcttggtt gaagtcgtct gcgattgtct ttttcgtttc
     4561 tcataaaagt ccgcgatatg acaaggattg gtatgactag ctgaagcaat attgtggacg
     4621 cacttataga gaatttttct cgcgtaagga tttccacgct tggtgatatg ttcttgagct
     4681 aggaaattgc cagattcata gtgtctgagg tcaatactga taaaggcatt gatttggttg
     4741 gcagaccgaa agcgacgaat gtctccaatt cgccaataat gcttgtagct gttgtttctg
     4801 cgataccagg aatagagagc agaatctcgt attcaggtaa tggttcagcc aattcaatca
     4861 tttgtgctaa gtcctgatcc ttgcggtttg tcagtctcaa cagttcctgt gcatgatact
     4921 taacctcttc tgtcatggga gaggtttttg aaatggcaag ataggactgt tcggccagct
     4981 cgctcaactt ttcagccaat cgtccaactc tgttctcaga aatccgttta gaagttgaat
     5041 tacgatggct tcttttagct caactactga taatttcagc ctccaatgct tggttggaaa
     5101 gatggtcacg aggttccaat attgttcccc tgtaggagta gagagaaggt tctttatttc
     5161 tggaaaggca atttgaagca ccttgtgcag gctattctta gtcctaacga tgtcttctgt
     5221 cagattctga tagaatcgac tgaggtcacg caaattttga tagacttctt cttgaacata
     5281 agttggtttg cggttaagga tgaattgtga cgaagctagc ttttcagcgt caatctgatt
     5341 ggttttacgg actcgcaaac tgtctagttg cttcttagtt ttaaaggatt tagccgtata
     5401 taagcatagc tattgtcctc cagaaaggcc tgaagacgag aatagacccc tgtgcctcga
     5461 agataatctc aggtgtattt acctatttca aatcctctag aagacgacta aatccgatgg
     5521 catcattggg catggtatag ccatgaacct tttcaccatt cacaagaata gcgacttctg
     5581 agcttgcctt actcacatcc attctgaaaa ctgtccgcat catgtttacc cctttgtctt
     5641 gaatgactcc ttgttttagt gattttattt ccaatactcg acgtctagta tcccacatac
     5701 tttgataaaa ttcttcctaa aacaggtttc ttgccagttt gtcaagcgac gtctagcacc
     5761 atagagagct ctatgactta acaagacacc actattttaa cacaaagaaa aagtaatgag
     5821 tactctctcc cgttggagat ttcctcacta ctaatcttag tatgtttgtc aactgtagtg
     5881 atagacgaat aatcaagttc tggagaaggt cagattgggc gattacttat tattttccta
     5941 gcttgtacgg tgcttttatc gctatgaaaa agtttattcc aaaatctttt tttagtaact
     6001 tatagcttac ttactgttat accaactatt tctaaaatct tataaattat tttatgcata
     6061 ttttgcataa aattccaaat ttgataatct tcaaattaca atattagtaa gaggattatt
     6121 aatgtatatc agattaaaga atttaagaga agacaaagat ttgtcccagt gtcaaattgc
     6181 acagtatctt cattgttcac agtctgctta ttctagaata gaaagtggca agcaagatat
     6241 tcctacatca tttttgaaac aattagctaa attatatcag gtaactacag attatatttt
     6301 agagatggat aagtttagtt gttaataaat cctaagccct ttgaaaactg aataaaccga
     6361 ggtgggactt tcttatttgt cgagcacttt agcttgatac gccgtgatag gagcgataat
     6421 tattagctat aaaatagagt ggttctctat ctgccatgac tacaaataag gataatgata
     6481 cttctgaacg ttcaggctgc cagcgaaaaa ggacagcggg tgaaatgccc atgaatgatt
     6541 taaccagtca tacccacgga ggaaattata catgttacaa ggaggaaaaa gtttggaaca
     6601 atcagtaata aagtatacta tgcaactatc aatgcttaac tttttatact caagaaatat
     6661 gttatctaaa aatgagtatg acaagattag aaacaaactg cgtattaagt acacaaaata
     6721 gctgactttt tgatttgaat gcggtaatat agaatcaaaa ggaggaattt cagtatgaaa
     6781 aaaaataatg ttgaaataat aaaagctgat tctttagttc gtcgaagagg cgacaatgta
     6841 gaaagacact taaagagggt tgctgcttat tgcagagtta gttccgatag tgaggatcag
     6901 aaaaacagtt atgattctca agtaagacac tacaaagaat atatttctca gcgttcagat
     6961 tgggagctgg cagatattta tgcagatgaa ggtatttcag gaacacaagt aggaaagaga
     7021 caagattttc aacgattaat caatgattgt gcaaatggag agatagatta tattgtcaca
     7081 aaagcaattg ctagatttgc aaggaatacc ctagatactt tgaagtatgt cagaatgtta
     7141 aaggatatgc aaattggagt atattttgag gaagaaaaca tagataccct aacaatggat
     7201 ggagaattgc ttctaactat tctaagctcc gttgcacagc aagaagtaga gaatacttct
     7261 gcccatgtga aaaaaggatt aaaaatgaag atgcaacgtg gtgaattggt tggttttcaa
     7321 gggtgcttag ggtatgatta tgatgtagaa accaagcaga tttcaattaa taaaaaagaa
     7381 gccaaaattg ttcgttatat ttttgaaagg tatctagaag gtattggagg aaaagtaatt
     7441 gcaagggaac ttgatgaact tggttacaaa tcgccaagag gtttagaaca ctggaatgat
     7501 acaacagttc taggaataat aaagaatgaa aaatataaag gtgatattct aatgggaaaa
     7561 acttttacag ttgacccaat aagcaagaga cggttgagta attttggaga agaagataag
     7621 tactatatca aggataatca tgaaccaata atatctaaag aagattttga aaaagctcag
     7681 gagattagat tgcgtcgagc aggaaataag aagacagctg cgaatgtaaa tgggaagcgt
     7741 gaacgctatt caaaaatgta tgcttttagt agcatgttgg aatgtggttt ttgtggttca
     7801 atattatcta gaagaagttg gcactgccgt tcagattatc gcaaagttgt gtggcactgt
     7861 gttacatcga taaagaaagg aaagaaattt tgtaagcata gtaaaggatt agaagagatc
     7921 gccattgagg gggctttcct ggaagcttac agacaagtct atcattcaaa tgaaaattta
     7981 atgacagact tacttgaaac gatagaatct gaattgaatg acaatagcct taacaaggaa
     8041 ctaaaaagga ttacaaacaa acttcgaata ttactaaaaa aagaggagaa tcttgtaaat
     8101 ctaaggctcg aaggaaaagt tagcgattcc atatacaatg aaaagtacaa tgaaatttcc
     8161 tcagaaaaag agtttctagc agaagagaag gtaaatattg aaacaacatt aaaatcagaa
     8221 atcgatgtaa agaaaagact aactgagttt aagcacttgc tatcttcgca aaaaatgctt
     8281 acggagtttg atcgtgcagt ttttgaaagt attgttgaga aaattattgt aggtggagtt
     8341 aatagcaacg gagaaattga tcctgcaatg ttaaccataa tattcaaaac aggtgaaatt
     8401 caaaacaagg atggtaaaca atttaaaagt aaacgtaaaa atgctaaact agaaacagat
     8461 aaattgtgtc ctcaaaacag tgacgaggat aaaaaattgt attctcaagg aacagacaac
     8521 acacgtggag tgtgtagtgt tgctggttcg atcttagcca gtcaataaaa tgatatgttt
     8581 taaaaaaatt ataatttcga aacgtgaata aacttgttta aactttatgt atctttagaa
     8641 agtgtgttaa cttgaaagaa caaatttttt tgatgggtgg gaatccccca ataaagaaat
     8701 atagtattgt tgataaaatt gtattatcaa ccaagattaa aagaattatc atttttacag
     8761 tttttcgaga aaattgggaa ccgtacatga aaaagtacac ggaagttttt caaagtcaat
     8821 ttcctaatct aaacattgat tacttgctcc tggacactga gcagattgat cttgatagct
     8881 atctagatgc tgacataatt atcatcggtg gtggaaatac ggaaaaatat attgctactt
     8941 atattaatca ggagttcaaa agttatatcg atcatatgct taataaagag gcaaaaatta
     9001 taggattttc tgcaggaccc ctactattag gagaaaaagt ctatgtctca cctaatgata
     9061 attcagatca tcagataaag ataaaaaatg gattaggact ctttagtcag tttttaatta
     9121 gtgtccatta tgattcctgg aatgataaag caaataagga tagagctgaa gaactcgata
     9181 atgttcccat aattccacta aatgatcatt cttgtcttgt attggataaa cttggaaaca
     9241 tcatagagaa aattgactaa ctttcataat gtaaaaatgg atctaggaaa taaaagtgta
     9301 gacgaactgg ataggttact agtgaaaact gcaaaaagtg ttgtaaagtg aatcggagtg
     9361 tgcttgatgg attttagtag taagatagcc ataaataaag gctggtcaga tgataaaaaa
     9421 tattgtgtga cagatcaaaa tcagtaaaaa tatttcttgc gtgtttctga taagtcgaag
     9481 ttagattata aaaaaatttg aatttgatat gatggagaaa gtagcttctc ttggagttcc
     9541 gatgtgtaaa ccaattagca ttgaactctg cgatgacgaa gtacattctt tacacgaatg
     9601 gatagacgga agagatgcaa tagatagcat tttaacttat tcagaaaacc aacaatacac
     9661 atatggtgta gaagcaggaa agatacttag aaagattcat acaattcctg ctacagaagt
     9721 ttgtgaagat tgggaaatct tttttaatct aaaaattgat gataaaatct ccaacgaaat
     9781 gatatggtaa gtccgaaacg ctcagtgtgt aagcttgttg ctaaaagcgt aaaaaccttg
     9841 gaacgaaagg aataatagac ttcctgcgaa acaaaaatac aatacaataa aactatggat
     9901 gatgaagcaa gtaaacaatt aagcgatagc cgtttcaaga gccttgtagg tgttcagcgc
     9961 acgagatgtt agctgtgtta aaaacagctt atcaacgcaa cgtaaacgcg caaaaggtgg
    10021 acgaaaaacc aaattaagcc tagacgatct cctcatggta actattcaat acatgcgaga
    10081 atagcgcact tatgaacaaa ttgcggctga ttttggcatt cacgaaagca acttaatccg
    10141 tcggagccaa tgggttgaag taactcttgt tcaaaatggt tttacgattt caaattctgc
    10201 cctaattatg aaaaacagta aaattcgaag gattgtaagg taagagtttt tttctttctg
    10261 aaaaaatggt ataatagcaa tcaaaactag aaaataaaac ggaatttgga acagatttgt
    10321 ctgtatccta gtagagtggt gatgctatga agattagtaa gaggcactta ttaaattatt
    10381 ccatcttgat tccctacttg cttttatcta ttttgggctt gattgtggtc tattcgacca
    10441 ccagtgctat tttaattgaa gaaggcaaga gcgccttgca gttggttcga aaccaaggaa
    10501 tcttttggat tgttagtttg atactgattg ccttaattta taaattgaga ctagattttt
    10561 tgagaaatga gcgactaatc attttagtta tattaataga aatgctttta ttgttcttgg
    10621 ctcgttttat tggtatttcc gtaaacgggg catacggttg gatttcggtt gcaggaataa
    10681 ctattcagcc agctgagtac ttaaaaatca ttattatttg gtatttagct caccgattct
    10741 ccaaacagca agaagaaata gctacttatg attttcaagt tttgactcaa aatcaatggc
    10801 ttccccgtgc ttttaatgat tggcgattcg ttctcctagt tctgattgga agtttgggaa
    10861 ttttccctga tttaggaaat gcgactattt tagtcttggt ttccttgatg atgtatacag
    10921 ttagtggaat cgcttatcgc tggttttcaa ccattctggc gctcgtatct gccgcttctg
    10981 tctttgtctt gaccactatc agcctaatcg gtgttgagac cttttcaaaa attccagtat
    11041 ttggctatgt agccaagcgc tttagtgcct tttttaatcc ttttgccgat cgtgctgatg
    11101 caggtcacca gttagctaat tcttattttg ccatggtcaa tggcggttgg tttggtctag
    11161 gtcttggaaa ctcgattgaa aaacgaggtt atttgccaga agctcataca gactttgtct
    11221 tttctatcgt gattgaagaa tttggctttg ttggtgccag tcttatttta gctctcttgt
    11281 ttttcatgat tttgcggatt atcttggtcg gtatccgagc ggagaatcct ttcaatgcca
    11341 tggttgcact cggtgtcgga gggatgatgt tggttcaggt atttgtcaat atcggaggga
    11401 tttcgggctt gattccatct acaggagtga ctttcccctt cttatcccag ggtggaaata
    11461 gtcttctagt cttatcagtg gcagtagcct ttgtcttaaa tattgatgcc agtgaaaaac
    11521 gcgctaaatt gtaccgagaa ttggaaaatc aaccaatgaa ccttctgttg aagtaggata
    11581 aagaaaggat agtttatgtc tcttcaaaaa ttagaaaatt atagtaataa aagtgttgtg
    11641 caagaagaag tcttgattct aacagaatta ctggaagata ttactaaaaa tatgcttgcc
    11701 ccagagacct ttgaaaaaat aatacagttg aaagaattat caacgcagga agattatcaa
    11761 ggtctaaacc gtctagtgac tagcttatca aatgatgaaa tggtctatat ttcacgctat
    11821 ttctctatct tgcctctttt gattaatatt tcagaggatg tggatttagc ttatgaaatc
    11881 aatcatcaaa ataatattga tcaggactat ttaggtaaat tatctacaac gattaaattg
    11941 gtagcagaaa aggaaaatgc cgttgagatc ctagaacact tgaatgttgt ccctgttttg
    12001 acagcccatc caacacaagt gcaacgcaaa agtatgttgg atttaacaaa tcatattcat
    12061 agtcttttgc gtaaataccg tgatgttaag ttggggttga tcaataaaga taaatggtac
    12121 aatgatttgc gtcgttacat cgaaattatc atgcagacag acatgattcg tgagaaaaaa
    12181 ttaaaagtga ctaacgaaat cacgaatgct atggaatatt ataacagctc ctttttgaaa
    12241 gctgtacctc atttgacgac ggagtataag cgcttagcgc aagcgcatgg tctgaattta
    12301 aaacaggcta aaccaatcac catgggtatg tggataggtg gtgaccgtga tggaaatcca
    12361 tttgttacag caaagacctt gaagcagtct gcactcactc agtgtgaagt catcatgaac
    12421 tactatgata aaaagattta ccaactttat cgtgaatttt ctctttcaac tagcattgtc
    12481 aacgtcagca agcaagtcag agaaatggct cgtcaatcca aggataactc gatttaccgc
    12541 gaaaaagagc tttaccgtcg tgccttgttt gatattcaat caaaaattca ggcaactaaa
    12601 acctatctga ttgaggatga agaagttggg actcgttatg aaaccgccaa tgatttctac
    12661 aaggatttga ttgccattcg agattctcta ctagaaaata agggcgagtc cttgatttca
    12721 ggtgattttg tggaattatt gcaggcagta gagatatttg gtttttactt agcatcaatt
    12781 gatatgcgac aagactctag cgtctatgaa gcctgtgtgg cagaactctt gaaatcagca
    12841 ggaattcatt ctcgttatag cgagttgagc gaagaagaaa agtgtgacct tctcttgaaa
    12901 gaattagaag aagatccccg aattctttct gcgactcacg cagaaaaatc agaattatta
    12961 gcaaaagaac tagctatttt taagacggct cgtgttttga aagataagtt gggagatgat
    13021 gtcatccgtc agaccatcat ttcacatgca accagccttt ctgatatgct agaattagct
    13081 attctgttaa aagaagtagg actggtggat acggaaaggg cgcgtgttca gattgttccc
    13141 ctttttgaaa caattgaaga cttggatcat tcagaggaaa caatgagaaa atatctttct
    13201 cttagccttg ccaaaaaatg gattgactca cgaaataact atcaagaaat catgcttggc
    13261 tactctgaca gtaataaaga tggcggttac ttgtcatcat gttggaccct ctacaaggct
    13321 caacaacaat tgactgctat tggagatgaa tttggcgtta aggttacctt cttccatggt
    13381 cgtggtggta ctgtcggtcg tggtggtggg ccaacctatg aagccattac atctcaaccg
    13441 ctcaagtcta tcaaggatcg tatccgcttg acggagcagg gtgaagtaat tgggaataaa
    13501 tacggtaaca aagacgccgc ttactataac cttgaaatgc tagtatcggc agctattaac
    13561 cgtatgatta ctcagaagaa gagcgatacc aataccccaa atcgttatga agccattatg
    13621 gatcaagtag tggaccgtag ttacgatatc taccgtgatt tggtctttgg taatgagcat
    13681 ttctatgatt atttcttcga gtcaagtcca atcaaggcta tttcaagttt taatattggt
    13741 tctcgtccag ccgctcgtaa gactattact gaaatcggtg gattgcgtgc tatcccttgg
    13801 gtattctcat ggtcacagag tcgtgttatg ttccctggat ggtacggggt tggttcaagc
    13861 ttcaaggaat ttatcaataa aaatccagag aatattgcta tcttacgaga tatgtaccaa
    13921 aattggcctt tcttccaatc gcttctttca aatgttgata tggttttgtc aaaatcaaat
    13981 atgaatattg cttttgaata tgctaaactt tgtgaagacg agcaagttaa ggccatctat
    14041 gagactattt taaatgaatg gcaagttact aagaacgtta tcttggctat tgaaggacat
    14101 gacgaactct tagctgacaa tccatatcta aaagctagtc tggattaccg tatgccttac
    14161 tttaatattc tcaactatat tcagttagag ttgattaaac gccaacgtcg tggagaattg
    14221 tccagtgatc aagaacgatt gattcatatc accatcaacg gaattgcgac aggattgcgt
    14281 aattcaggtt gataattttc aagagtgaat gctaaaagtg aatatcaaaa aaattctaat
    14341 agactattga caagtagttt aaaaatgata taatttaacc attcagaaaa gtaatcatac
    14401 aaacttttta gagagtctgt ggtagctgaa aacagataag tggcaatgat gaaaattggg
    14461 ctgaatgcta tttagaattt gaaattataa aaattcggta agcacacctt acagtgcatc
    14521 tcgttattgc gagactgagc gatagggaaa ttccctataa ttgaggtggt accgcgcatc
    14581 gacgtcctca cacaagtttt ttgtgtgagg atttttttga tggaggttag tatagaaaga
    14641 aaacgatggc gtcgcttgtt tagataagtg aaatatgtta aaggaaataa aaaggagaaa
    14701 cagaatgaaa aataaacgtt taattggaat tattgctgca ttagcagtct tagtagcagg
    14761 aagcttgatt tattcttcaa tgaataaatc agaagctcag aataataagg atgagaagaa
    14821 aataaccaag attggtgtgc ttcaatttgt gagccatcca tcccttgatt tgatttataa
    14881 agggatccaa gatggacttg cagaagaagg atataaagat gatcaagtta aaattgattt
    14941 tatgaactca gaaggtgacc aaagtaaggt tgcgacaatg agtaaacaat tggttgcaaa
    15001 tgggaatgac cttgtggttg gtatcgcaac accagcagcc caagggttgg ctagtgcaac
    15061 aaaagaccta ccggttatca tggccgctat tacagaccca attggtgcta acttggttaa
    15121 agatttgaaa aaaccaggtg gcaacattac aggggtatct gaccacaatc cagctcaaca
    15181 acaagttgaa ctcatcaagg ctctgacacc gaatgtgaaa acaatcggag ctctttactc
    15241 aagtagcgaa gacaattcaa aaacacaggt cgaagaattt aaggcttatg ctgaaaaagc
    15301 aggtctgaca gtggaaacat ttgcagttcc ttcaacaaat gaaattgcct caactgtcac
    15361 tgttatgact agcaaggtag atgctatttg ggttccaatt gataacacca ttgcatcagg
    15421 atttccaacg gttgtctcta gcaatcaaag ttctaagaaa ccaatttatc ccagtgcgac
    15481 agctatggta gaagtaggtg gtttggcatc agttgtaatt gaccaacatg accttggtgt
    15541 ggcaacaggt aaaatgattg tgcaagtctt gaaaggtgca aaaccagccg ataccccagt
    15601 caatgtcttt tcaactggta agtcagtcat caataaaaaa atagcacaag aactaggtat
    15661 tactattcct gagtttgttc tcaaagaagc aggacaagtc atcgaataaa taaggtaggg
    15721 aggaggagac tcttcccatt ttttaaaaag atgaatatag aaaggattaa ataaaatatg
    15781 attgtttcca ttatttctca aggatttgtc tgggctattc taggtctggg aatctttatg
    15841 acatttagga ttttaaactt tccagatatg acgacagaag gttccttccc tcttggggga
    15901 gctgttgctg tcactttgat aaccaaaggc gtgaacccat ttttagcgac acttgttgct
    15961 gtaggagcag gttgtttggc tggaatggca gcaggccttc tttatacaaa agggaagatc
    16021 ccaaccttgc tctcagggat tttggtgatg acttcttgtc actcaatcat gctcttgatt
    16081 atgggacgtg caaatttagg cctgcttgga accaagcaaa ttcaggatgt tttgcctttt
    16141 gattcggatt tgaatcaact cttgacaggt ctcatctttg tgagtattgt tattgctctc
    16201 atgctctttt tcttggacac taaactcgga caagcctata ttgctacagg ggataatcct
    16261 gatatggcta gaagtttcgg gattcatact ggacacatgg agctcatggg cttggtctta
    16321 tcaaatggtg tgattgccct tgcaggtgcc ctcattgctc agcaagaagg ttatgccgat
    16381 gtgtctcgag ggatcggggt tatcgttgtg gggcttgcaa gtttgattat tggagaagtt
    16441 attttcaaga gtttgagctt ggcagagcgt ttggttacta tcgttgtagg ttctatcgct
    16501 tatcaatttt tagtgtgggc agttatcgca cttggcttta atacaagtta ccttcgttta
    16561 tacagtgcct tgattttagc agtctgcctc atgattccaa catttaagca aacaatcttg
    16621 aaaggagcca agttaagcaa atgacagcaa ttgtagaatt aaaaaatgca accaaaatcg
    16681 ttaaaaatgg ctttgatgaa gaaaagatta ttttaaatga tgtttcctta gaaatttttg
    16741 aacaggactt tatcacgatt ttgggtggaa atggtgctgg taaatcaacc ctctttaaca
    16801 ctattgcagg aaccatatca ctaaccagtg gaactatccg tattttaggt gaggatgtta
    16861 ccaagttttc accagagaag cgcgctaagt atctgtctcg agtcttccaa gatccaaaga
    16921 tggggacagc tcctcgtatg acagtggcag agaatctcct gattgccaag tttcgtggtg
    16981 aaaagcgtgg actatttccg agacgtctgg ctagctataa ggataagttt caggcgacca
    17041 ttgaaaaagt gggaaacggt cttgagaaac acttgaatac accgattgag ttcttatctg
    17101 gtggacaaag acaggctttg agtctcttga tggcaacctt gaagcgacct gaattactct
    17161 tgttagacga gcatactgct gccctggatc caaagactag tgttgctttg atggaattga
    17221 cagatgaatt tgttaagaaa gatcaattga cagcccttat gattacccat catatggaag
    17281 atgctctcaa atatggcaat cgcttgattg tcatgaaaga aggacgggtt atccaagatt
    17341 tgaaacaaga agaaaaagca aaaatgaaaa tctctgatta ttatcaactc tttgaataaa
    17401 gtagggaaaa tgagtgaaat ggtttacttt ttttctgaaa taaagtatac tatataaagt
    17461 aaactatgat aacatggagg tattgtgtat ggttgacaaa caagtcattg aagaaatcaa
    17521 aaacaatgcc aacattgtgg aagtcatagg agatgtgatt tctttacaaa aggcaggacg
    17581 gaactatcta gggctctgtc cttttcatgg tgaaaaaaca ccttctttca acgttgtaga
    17641 ggacaagcag ttttaccact gttttggttg tggtcgctca ggtgatgtct ttaaattcat
    17701 cgaggagtac caaggggtta cctttatgga ggctgtccaa atcttaggtc agcgtgtcgg
    17761 gattgaggtt gaaaaaccgc tttatagtga acagaagcca gcctcgcctt accaagctct
    17821 ttatgatatg cacgaagatg cggctaaatt ttaccatgct attctcatga caacgactat
    17881 gggcgaagag gccagaaatt acctttatca gcggggtttg acagatgaag tgcttaaaca
    17941 tttttggatt ggtttagcac ctccagaacg aaactatctc tatcaacgtt tgtctgatca
    18001 gtatcgtgaa gaggatttac tggattcagg cctgttttat ctctcggatg ccaatcaatt
    18061 tgtagacacc tttcacaatc gcattatgtt tcccctgaca aatgaccaag gaaaggtcat
    18121 tgccttctca ggtcgtatct ggcaaaaaac ggattcacaa acttctaagt ataaaaacag
    18181 ccgatcgact gcaattttta acaaaagtta cgaattatat catatggata gggcaaaaaa
    18241 atcttctgga aaagctagtg agatttacct gatggaagga ttcatggatg ttattgcagc
    18301 ctatcgggtt ggaatcgaaa atgctgtggc gtcgatggga acggccttga gtcgagagca
    18361 tgttgagcat ctgaaaaggt taaccaagaa attggttctt gtttacgatg gagataaggc
    18421 tgggcaagcc gcgatattga aagcattgga tgaaattggt gatatgcctg tgcaaatcgt
    18481 cagcatgcct gataacttgg atcctgatga gtatctacaa aaaaatggtc cagaagactt
    18541 ggcctatcta ttaacgaaaa ctcgtattag tccgattgag ttctacattc atcagtacaa
    18601 acctgaaaac agtgaaaatc tgcaggctca gattgagttt attgaaaaaa tagctccctt
    18661 gattgttaaa gaaaagtcca tcgctgctca aaacagctat attcatattt tagctgacag
    18721 tctggcgtcc tttgattatg cccagattga gcagattgtt aatgagagtc gtcaggtgca
    18781 aaggcagaat cgcatggaaa gaatttccag accgacgcca atcaccatgc ctgtcaccaa
    18841 gcagttatcg gctattatga gggcagaagc ccatctactc tatcggatga tggaatcccc
    18901 tcttgttttg aacgattacc gtttgcgaga agactttgca tttgctacac ctgaatttca
    18961 ggtcttatat gacttgcttg gccagtatgg aaatcttcct ccagaagttt tagcagagca
    19021 gacagaggaa gttgaaagag cttggtacca agttttagct caggatttgc ctgctgagat
    19081 atcgccgcag gaacttagtg aagtagagat gactcgaaac aaggctctct tgaatcagga
    19141 caatatgaga atcaaaaaga aggtgcagga agctagccat gtaggagata cagatacagc
    19201 cctagaagaa ttggaacgtt taatttccca aaagagaaga atggagtaat aatggcaaca
    19261 aaacaaaaag aagtaacaac atttgacgta caggtagcag aatttatccg taatcataag
    19321 caaaaaggga cagcaacaga tgatgaaatc aatgcaagtc tggttattcc ttttaccttg
    19381 gacgctgatg ggattgaaga tctcttgcaa cggattcagg atgcaggcat ttctatcaca
    19441 gataacgaag gaaatccaag tgcgcgtgtt cttagcaatg aagaagaacc agaactcagc
    19501 gatgaggact tgattgggtc aacttctgct aaggtcaatg accctgtccg tatgtacttg
    19561 aaagaaatag gggtcgttcc tctcttgacc aatgaagagg agaaagagtt ggcactggct
    19621 gttgaagctg gcgatatcga agccaaacaa cgtcttgcgg aagccaatct tcgtttggtt
    19681 gtttccattg ccaaacgcta tgtcggtcgt ggcatgcagt tccttgactt gattcaagaa
    19741 ggaaatatgg gcttgatgaa ggcggttgac aagtttgact attctaaagg gttcaagttt
    19801 tcaacttatg caacttggtg gattcgtcag gctatcactc gtgctattgc ggaccaagct
    19861 cgtaccatcc gtatcccagt tcacatggtt gaaactatca ataaattggt tcgtgaacag
    19921 cggaatctcc ttcaagaatt ggggcaagat ccgacaccag aacagattgc tgaacgaatg
    19981 gatatgacac ctgataaggt tcgtgaaatc ttgaagattg cccaagaacc agtatctctt
    20041 gaaactccta tcggtgaaga ggacgatagc caccttggag actttatcga agatgaagtg
    20101 attgaaaatc cagtggatta tacgactcgt atcgtcttgc gtgagcaatt ggatgaaatc
    20161 ttagatactc ttacagaccg tgaagaaaat gttctgcgtc tacgttttgg actagatgat
    20221 ggaaaaatgc gcacacttga agatgtgggg aaagtcttta acgtaactcg tgagcgtatc
    20281 cgtcagattg aagcaaaggc tttgagaaaa ctacgccaac caagtcgcag caaaccgctt
    20341 cgtgatttta ttgaagacta agagtgagga aaatatggct tatacagaag agcaaattga
    20401 aaacatcaaa acacggattt taacagcctt ggaagaagtc atcgaccctg agttgggaat
    20461 cgatattgtc aatcttggtt tgatctatga gattcgtttt gacggtgaca cagggcaaac
    20521 agagattgac atgactttga caactatggg ttgtccctta gcagaccttt tgacagacca
    20581 gatttatgat gctatgatag aggttccaga agtaacggat actgaggtta aattagtctg
    20641 gtatccagcc tggacagttg aaaaaatgag tcgctatgcc cgcattgccc taggcattaa
    20701 gtaaacatat aaaagcatgt gagagactgt tggaaaagcg aggaa
//
LOCUS       DAYYYC010000037        20657 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.037, whole genome shotgun sequence.
ACCESSION   DAYYYC010000037 DAYYYC010000000
VERSION     DAYYYC010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20657
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.037"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            77..688
                     /locus_tag="ACHBV5_001443"
     CDS             77..688
                     /locus_tag="ACHBV5_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFM9967217.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            849..1643
                     /gene="ccrZ"
                     /locus_tag="ACHBV5_001444"
     CDS             849..1643
                     /gene="ccrZ"
                     /locus_tag="ACHBV5_001444"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HFM9967218.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            1640..2275
                     /gene="trmB"
                     /locus_tag="ACHBV5_001445"
     CDS             1640..2275
                     /gene="trmB"
                     /locus_tag="ACHBV5_001445"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFM9967219.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            2401..2880
                     /gene="rimP"
                     /locus_tag="ACHBV5_001446"
     CDS             2401..2880
                     /gene="rimP"
                     /locus_tag="ACHBV5_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFM9967220.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMGKTRKKTVQIPYSLVSKARLAVKL"
     gene            2924..4060
                     /gene="nusA"
                     /locus_tag="ACHBV5_001447"
     CDS             2924..4060
                     /gene="nusA"
                     /locus_tag="ACHBV5_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFM9967221.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            4082..4375
                     /locus_tag="ACHBV5_001448"
     CDS             4082..4375
                     /locus_tag="ACHBV5_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFM9967222.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            4368..4667
                     /locus_tag="ACHBV5_001449"
     CDS             4368..4667
                     /locus_tag="ACHBV5_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFM9967223.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            4684..7476
                     /gene="infB"
                     /locus_tag="ACHBV5_001450"
     CDS             4684..7476
                     /gene="infB"
                     /locus_tag="ACHBV5_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFM9967224.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKTEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            7727..8077
                     /gene="rbfA"
                     /locus_tag="ACHBV5_001451"
     CDS             7727..8077
                     /gene="rbfA"
                     /locus_tag="ACHBV5_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFM9967225.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            8357..9136
                     /locus_tag="ACHBV5_001452"
     CDS             8357..9136
                     /locus_tag="ACHBV5_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967226.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            9138..9320
                     /locus_tag="ACHBV5_001453"
     CDS             9138..9320
                     /locus_tag="ACHBV5_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967227.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(9505..9738)
                     /locus_tag="ACHBV5_001454"
     CDS             complement(9505..9738)
                     /locus_tag="ACHBV5_001454"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967228.1"
                     /translation="MKIKEQTRKLAADCSKQCFEVVDRTDEVSSKHRFEVVDRTDEVS
                     NHTYSKVKLTWFEEIFEEYKMILLLILYHMERD"
     gene            9769..10002
                     /locus_tag="ACHBV5_001455"
     CDS             9769..10002
                     /locus_tag="ACHBV5_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HFM9967229.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            10002..11336
                     /locus_tag="ACHBV5_001456"
     CDS             10002..11336
                     /locus_tag="ACHBV5_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HFM9967230.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYEYMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKDDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            11346..11600
                     /locus_tag="ACHBV5_001457"
     CDS             11346..11600
                     /locus_tag="ACHBV5_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HFM9967231.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            11696..12091
                     /locus_tag="ACHBV5_001458"
     CDS             11696..12091
                     /locus_tag="ACHBV5_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFM9967232.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQPAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            12374..12951
                     /locus_tag="ACHBV5_001459"
                     /pseudo
     CDS             12374..12951
                     /locus_tag="ACHBV5_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813803.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
     gene            12938..13498
                     /locus_tag="ACHBV5_001460"
     CDS             12938..13498
                     /locus_tag="ACHBV5_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFM9967233.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHIFPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLDFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            13498..14076
                     /locus_tag="ACHBV5_001461"
     CDS             13498..14076
                     /locus_tag="ACHBV5_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFM9967234.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAEILQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            14069..16720
                     /locus_tag="ACHBV5_001462"
     CDS             14069..16720
                     /locus_tag="ACHBV5_001462"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFM9967235.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVIAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDATVARIDEMKKLVK"
     gene            16801..16965
                     /locus_tag="ACHBV5_001463"
     CDS             16801..16965
                     /locus_tag="ACHBV5_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFM9967236.1"
                     /translation="MGKIVAIDLFNGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDME"
     gene            17016..18620
                     /locus_tag="ACHBV5_001464"
     CDS             17016..18620
                     /locus_tag="ACHBV5_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFM9967237.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNVKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFLRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWFDGDQNTNVSESNNLMNYLEN
                     GVVISDKIPESDNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKY
                     VSYLPFPTPEFFLANLCNSVDREGYDFSKDGNGKEYFRKKTQVALGIENITSEDIFQE
                     QRRAVSKIQPESSMFQCIKEKLEALF"
     gene            18657..18782
                     /locus_tag="ACHBV5_001465"
                     /pseudo
     CDS             18657..18782
                     /locus_tag="ACHBV5_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378463.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            19000..19803
                     /locus_tag="ACHBV5_001466"
     CDS             19000..19803
                     /locus_tag="ACHBV5_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFM9967238.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(19919..20657)
                     /locus_tag="ACHBV5_001467"
                     /pseudo
     CDS             complement(19919..20657)
                     /locus_tag="ACHBV5_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         6405 a         3797 c         4605 g         5850 t
ORIGIN      
        1 taaaatggtt tgttttggaa aggctagaac taaagaatga cgtgtaggaa gtctgtttgt
       61 tgaggaggat aattttatgg agttttttga taaatttcat gccttgtgtt ttggattttt
      121 agtactaata attgtcatta cagttcctta tacgattaac catgggggtt tttttcaaaa
      181 tgaatctgca ttgattcttg taagtcttct tgtaacctcg ctgagtgttg cttatgctag
      241 aaagtttgaa atgatttctt ttgggatgtt aagcaagaaa caacttttgc ttttcattgc
      301 aatctttctt ctaagtgtac ttgagacgct ggtttatatt catttcttcg ctgtttcttc
      361 tggctcaggg gtccaacact tggcggaagt cagcagagga atttccctgt ctttgatttt
      421 gactacctca gtttttggcc ccatccagga ggaactcatt ttcagaggac ttcttcaagg
      481 tgcggttttt gacaattctt ggttagggct tgtgctaact tcctctctct tttctttcat
      541 gcatggacct tctaatgtcc cttcgtttat tttttatcta cttgggggtt tgttgctggg
      601 ctttgcttat aaaaagagtc aaaacctatg ggtttctact ctagtccata tgctttacaa
      661 cagttggcca ctcttatatt atttataaaa attatgaaaa ggtaagcaga agacggtgct
      721 tacctttttc aagctataat gatacccaag ccaatccaga ggcttttctt tgagaatcgg
      781 gttagagtgg ttgacgaata ggccaaaaac tagtagaata gtaaggaaac tttatacgga
      841 ggaaagaaat ggatttgggt gataatgagc taacactgac tcccatacct gggaaaagtg
      901 gcaaggctta tatgggtagc tatcctgatg ggaagcgcat ctttgtaaaa atgaacacct
      961 ctccaatcct acctggtcta gctagagaac aaattgctcc acaattatta tggagtcgtc
     1021 gtttggcaga tgggcgtgat atgtgtgctc aagaatggtt gacaggcaag atattgaccc
     1081 cctatgatat gaatcgtaag caaatcgtca atattttaac ccgtcttcat cgctcacgtc
     1141 cgttgatgac acaattgagt cgtttgggct atgccatgga aacacctgta gatttactac
     1201 agtcttggca ggaaacggct ccagatgctt tgcgtaaaaa tcattttatc agtgaagtga
     1261 tggctgattt acgtcagact attccaggat ttagagagga ccatgcgacc attgtccatg
     1321 gagatgtacg acatagtaat tggattgaga cagatagtgg cttgatttat ttagtagatt
     1381 gggattcggt tcgcttgacc gatcgcatgt ttgatgtggc ccatatgctc tgccattata
     1441 tttcagaaca tcagtggaag gaatggttga cctactacgg ttacaagtac aatcaaacgg
     1501 tattaagtaa attgtattgg tatggtcaat tgtcttattt gagtcagatt tccaagtatt
     1561 atatgaacca agatttagaa aatgtcaatc gggagattca tggtttgcgt catttccgag
     1621 acaagtatgg aaagagaaga tgagagttag aaatcgtaaa ggggcaacag aattactaga
     1681 ggcaaatccc cagtatgtgg tcctcaatcc cttggaagcc aaggcaaaat ggcgggactt
     1741 gtttggcaat gataatccca ttcatgtgga agttggaagt ggaaagggtg cctttgtttc
     1801 aggtatggcc aagcaaaacc ctgacatcaa ctatatcggg attgatattc aaaagtctgt
     1861 tttgagctac gctttggaca aggtgcttga agttggagtg cctaacatca agctcttgtg
     1921 ggtagatggt tctgacttaa ctgactactt tgaagacggt gagattgatc gcttgtatct
     1981 gaacttttca gatccatggc cgaaaaaacg ccatgaaaag cgtcgtttga cctacaagac
     2041 cttcttggat accttcaaac gtatcttgcc tgaaaatgga gaaattcatt tcaagacgga
     2101 taaccgtggc ttgtttgagt acagtttagt gagcttttct caatatggca tgaaactcaa
     2161 tggtgtctgg ttagatttgc atgccagtga ttttgaaggc aatgtcatga cagaatacga
     2221 gcaaaaattc tcaaacaagg ggcaagttat ctaccgagtt gaggcagaat tttaagagat
     2281 agcctaaaat taggctgtac aagtgctttt gctttacata agttggcaaa cgtgctatac
     2341 tgatagtaag aatatgaaaa gtgaggcggg gaaatatctt cgcctcttgc ttatgaggag
     2401 gtggacgcaa tcgcaacaat cgtagaatta gtcagagaag ttgtagaacc tgtcatagaa
     2461 gctccttttg aactcgtgga tatcgagtat ggaaagattg gcagtgacat gattctcagt
     2521 atttttgtag ataaacccga aggaattacc ttgaacgaca cggcagactt gacagaaatt
     2581 atcagtcctg tcctagacac catcaagcca gatcccttcc cagaacaata tttcctagaa
     2641 attaccagtc caggtttgga acgccctttg aaaaccaagg atgccgtcgc tggagcggtt
     2701 ggaaaataca tccatgtcgg gctctaccaa gccatcgata agcaaaaggt ctttgaagga
     2761 accttgttgg ccttcgaaga ggacgagttg actatggaat atatgggcaa gacgcgtaag
     2821 aaaaccgtcc aaattccata cagtttagta tcaaaagcac gtttagcagt taaattatag
     2881 aaaaagaaag gatagctttt gaggattcaa aagtgaagaa aacatgagta aagaaatgct
     2941 agaggccttc cgcattttgg aagaagacaa gggaatcaaa aaagaagata tcatcgacgc
     3001 agtagtagag tcgcttcgtt ccgcttatcg cagacgctat ggtcagtcag acagcgtagc
     3061 tattgacttc aacgaaaaaa caggtgactt tacagtttat actgtccgtg aagttgttga
     3121 tgaagtattt gatagccgtt tggaaatcag cttgaaagat gctcttgcca ttaattcagc
     3181 ttatgaactt ggagacaaaa tcaagtttga agaagcacca gctgagtttg gtcgtgtagc
     3241 agcccaatct gccaaacaaa ccatcatgga aaaaatgcgc aagcaaacac gtgccatcac
     3301 ttacaatact tacaaagaac atgagcaaga aatcatgtct ggtacagtag aacgctttga
     3361 caaccgcttt atctatgtca accttggtag catcgaagcc caattgtcaa aacaagacca
     3421 aattcctgga gaagtttttg cttctcatga tcgtatcgaa gtttatgttt acaaggttga
     3481 agacaaccct cgtggtgtga acgtctttgt tagccgtagc catccagaaa tgatcaaacg
     3541 tttgatggag caagaaattc cagaagttta tgatggaact gttgaaatca tgagcgtggc
     3601 tcgtgaagca ggtgaccgta cgaaggttgc tgttcgtagc cacaatccaa acgtggatgc
     3661 tatcggtaca atcgttggac gtggtggtgc taatatcaag aagattacta gcaaattcca
     3721 cccagctcgt tacgatgcta aaaatgaccg catggtacca atcgaagaaa atatcgatgt
     3781 tatcgagtgg gtagcagatc cagctgaatt tatctacaat gccatcgctc ctgctgaggt
     3841 tgaccaagtt atctttgatg aaaacgacag caaacgtgcc ttggtggttg ttccagataa
     3901 caagctttct cttgccattg gtcgtcgtgg acaaaacgtg cgcttggcgg ctcacttgac
     3961 tggttaccgt atcgatatca agtctgctag cgaatttgaa gccatggaag acgctgcttc
     4021 agtagagttg gaagtagaaa acgatactgt agaagaataa aagctgctag aggagggaaa
     4081 gatgaaaaca agaaaaatcc ctttgcgcaa gtctgttgtg tctaacgaag tgattgataa
     4141 gcgtgatttg ctccgcattg tcaagaacaa ggaaggacaa gtctttattg atcctacggg
     4201 caaggccaat ggccgcggcg cttatatcaa actagacaat gcagaagccc tagaggcgaa
     4261 aaagaagaag gtctttaacc gcagctttag catggaagtg gaagaaagct tttatgacga
     4321 gttgatcgct tatgtggatc acaaagtgaa aagaagagag ttgggacttg aataagcaaa
     4381 agataagtaa tctcttgggg cttgctcagc gagcagggcg catcatatcg ggtgaagaat
     4441 tggtggtcaa ggccattcaa gacggcaagg ccaagttggt ctttctagct catgatgctg
     4501 gacccaatct gaccaagaag attcaagata aaagtcatta ttatcaagta gaaattgtaa
     4561 ccgtgttttc aacactggaa ttaagcatag cagtcgggaa atcgagaaag gttttggctg
     4621 taacagatgc tggatttaca aagaaaatga ggtctcttat ggaatagaag aggaggacat
     4681 gatttgtcta agaaaagatt gtacgaaatc gcaaaagaac ttggaaaaga aagtaaagaa
     4741 gttgtagcgc gtgcaaaaga gttgggcttg gatgtgaaaa gccactcatc aagtgtggaa
     4801 gaagctgtcg ctgcaaaaat tgctgccagc tttaagcctg cagctgctcc gaaagtagaa
     4861 gcaaaacctg cagcaccaaa agtaagtgca gaaaagaaaa ccgaaaaatc tgagccagct
     4921 aaaccagctg tagctaagga agaggcaaaa ccggctgagc cagttgctcc gaaaacagaa
     4981 aaagtagcag cgaaaccgca aagccgtaat ttcaaggctg agcgtgaagc ccgtgctaaa
     5041 gagcaggcag aacgacgcaa gcaaaataag ggcaataacc gtgaccaaca acaaaacgga
     5101 aaccgtcaga aaaacgatgg ccgtaatggt ggaaaacaag gtcaaagcaa ccgcgacaat
     5161 cgtcgcttta atgaccaagc taagaagcag caaggtcagc aaaaacgtag aaatgagcgc
     5221 cgtcagcaag aggacaaacg ttcaaatcaa gcggctccac gtattgactt taaagcccgt
     5281 gcagcagccc taaaagcaga gcaaaatgca gagtacgctc gttcaagtga ggaacgcttc
     5341 aagcagtatc aggctgctaa agaagccttg gctcaagcta acaaacgcaa ggaaccagag
     5401 gaaatctttg aagaagcggc taagttagct gaacaagcac agcaagttca agcagtggtt
     5461 gaagtcgtcc ctgagaaaaa agaacctgca gtggatacac gtcgtaaaaa acaagctcga
     5521 ccagacaaaa atcgtgacga ttatgatcat gaagaagatg gtcctagaaa acaacaaaag
     5581 aatcgaagta gtcaaaatca agtgagaaat caaaagaata gtaactggaa taacaacaaa
     5641 aagaacaaaa aaggcaataa caagaacaac cgtaatcaga ctccaaaacc tgttacggag
     5701 cgtaaattcc atgaattgcc aacagaattt gaatatacag atggtatgac cgttgcggaa
     5761 atcgcaaaac gtatcaaacg tgaaccagct gaaattgtta agaaactttt catgatgggt
     5821 gtcatggcca cacaaaacca atccttggat ggggaaacaa ttgaactcct catggtggat
     5881 tacggtatcg aagccaaaca aaaggttgaa gtggataatg ctgacatcga acgtttcttt
     5941 gtcgaagatg gttatctcaa tgaagatgaa ttggttgagc gtccaccagt tgttactatc
     6001 atgggacacg ttgaccacgg taaaacaacc cttttggata ctcttcgtaa ctcacgtgtt
     6061 gcgacaggtg aagcaggtgg tattactcag catatcggtg cctaccaaat cgtggaaaat
     6121 ggtaagaaga ttaccttcct tgatacacca ggacacgcgg cctttacatc aatgcgtgcg
     6181 cgtggtgctt ctgttaccga tattacgatc ttggtcgtag cggcagatga cggggttatg
     6241 cctcagacta tcgaagccat taaccactca aaagcggcca acgttccaat catcgtagcc
     6301 attaacaaga ttgataaacc aggtgctaac ccagaacgcg ttatcggtga attggcagag
     6361 catggagtta tgtcaactgc ttggggtgga gattctgaat ttgttgaaat ctcagctaaa
     6421 ttcaaccaaa atatcgaaga attgttggaa acagtccttc ttgtagctga aatccaagaa
     6481 ctcaaggcag acccaacagt gcgtgcaatc ggtacggtta tcgaagcgcg cttggataaa
     6541 ggaaaaggtg cggtcgcaac ccttcttgta caacaaggta ccttgaatgt tcaagaccca
     6601 atcgttgtcg gaaatacctt cggtcgtgtc cgtgctatga ccaacgacct tggtcgtcgt
     6661 gttaaagttg ctggaccatc aacaccagtc tctatcacag gtttgaacga agcaccgatg
     6721 gcgggtgacc actttgccgt ttacgaggat gaaaaatctg cgcgtgcagc aggtgaagag
     6781 cgtgccaaac gtgccctcat gaaacaacgt caagctaccc aacgtgttag ccttgaaaac
     6841 ctctttgata cccttaaagc tggggaactc aaatctgtta atgttatcat caaggctgat
     6901 gtacaaggtt ctgttgaagc cctttctgcc tcacttcaaa agattgacgt ggaaggtgtc
     6961 aaagtgacta tcgtccactc agcggtcggt gctatcaacg aatcagacgt gacccttgcc
     7021 gaagcttcaa atgcctttat cgttggtttc aacgtacgcc ctacaccaca agctcgtcaa
     7081 caagcagaag ctgacgatgt ggaaatccgt cttcacagca ttatctacaa ggttatcgaa
     7141 gagatggaag aagctatgaa agggatgctt gatccagaat ttgaagaaaa agttattggt
     7201 gaagcagtta tccgtgaaac cttcaaggtg tctaaagtgg gaactatcgg tggatttatg
     7261 gttatcaacg gtaaggttgc ccgtgactct aaagtccgtg ttatccgtga tggtgtcgtt
     7321 atctatgatg gtgaactcgc aagcttgaaa cactataaag acgacgttaa ggaagttaca
     7381 aacggccgtg aaggtggatt gatgatcgac ggctacaatg atattaagat ggatgatgtg
     7441 attgaggcgt atgtcatgga agaaatcaag agataagatt ttttgctcct ttcttaggtg
     7501 gtgagggacg caagcaaacc gatggtttca ttgcttattt ttgagcctag ggtctcaaaa
     7561 atcccctgtg atgggactga taaatcagtt ccatcacttt caccacggcg aaagaagcag
     7621 atgacttcaa attgaacttc gtttcaattt aaactgaaaa tcaagaagtt taaaatagct
     7681 aggtctgctg gcctagcttt tggttcaaag tagagaaagg aatatcatgg caaatcattt
     7741 ccgtacagat cgtgtgggca tggaaatcaa gcgtgaagtc aatgagattt tgcaaaagaa
     7801 agtccgtgat ccacgtgtcc aaggtgtgac catcacagat gttcagatgc tgggtgactt
     7861 gtctgttgcc aaggtttatt acaccatttt gagtaacctt gcttcggata accaaaaagc
     7921 ccaaatcggg cttgaaaaag caactggtac catcaaacgt gaacttggtc gcaatttgaa
     7981 attgtacaaa atcccagatt tgaccttcgt caaagacgag tccatcgagt atggaaacaa
     8041 gattgacgag atgctacgca atctggataa gaactaaaga agaggggttg cccctctttt
     8101 ttggtggagg aaaataggtt gaatttgaaa tggaaaaata ttcttttaaa atatattgaa
     8161 actagaatag tacgcctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat
     8221 cgatttgtcc tgttcgtgtt tcattttact ataaaaaaag gggttctgta ttttttaatg
     8281 ttatctaatt agaaaatgct ttttttgtag gaaatataat atgataaggt gtaaaaaaga
     8341 aataaggagt ttgtatatgg ctgaacaaga cttagctatg caagtattac aacaagtggt
     8401 aaaactacca gttgttaagg ttgatcgttc gaaattttta gtggataagt tttccaaaga
     8461 attgggtcca caggacattc ctaccttatt ggaacaaggt ccaacgtctc tcttatctca
     8521 agaaatctta gatcgagtgg ctaatgcctg tattagggat aatgttttat tagcgagtgg
     8581 gacttctgtt ttggcaggat tacctggagg gcttgctatg gcaattacca ttccagctga
     8641 tgtggctcaa ttttatgctt tctctctgaa attggcccaa gaattaggtt atatttatgg
     8701 ttatgaggat ctttgggctt cacgcgatga gttgagtgaa gatgctcaaa ataccctctt
     8761 gctttatcta ggcgtcatgt tgggggtgaa tggaactgct gctttgctac gtgctggtgg
     8821 tataacaatt gccaaacagg taatgaaaac agtacctaat aaagctttaa ctaagacgct
     8881 ttggtatcct attttgaaaa aagtcttaag aatatttggt gtgaatctta ccaagggagg
     8941 gctggccaaa ggaatgggga aatttattcc tatcttgggt ggtatcattt caggtggttt
     9001 aacctttgca actatgaaac cgatgggtga aagcttgcag aaagaattgt ccaagctagt
     9061 taactatagt gaagttcaat atcaagaaga tgttgaaaca atccgaaaag aggctgaaat
     9121 catcgaagga gagtaatatg ggactcataa aaactctagc taaaatttat ggtaattact
     9181 ttttgaccgt gcaaggtgta aaagtgatga aaacgataaa gaaagctgac catgtcgttg
     9241 ttggtctggg caaacttttt attgcagata agctaatgga tacggctcgg tggctcatta
     9301 agccagagga gagagaatga aatttttttg gtcttcttgc tattcttttt atcaaaccga
     9361 ttattgggat tgtgaaattc ttttggatga tcatttcttt tgcagttcaa ttgctgtttt
     9421 acaagatatt ggattggttc tttaaactta tctagatggt aatccaagtc gcagaaaact
     9481 agcaggaacc ccactgctag ttttttaatc tctctccata tggtataata taagcagtaa
     9541 aatcatttta tactcttcga aaatctcttc aaaccacgtc agcttcacct tgctgtaggt
     9601 atggttactg acttcgtcag ttctatctac aacctcaaaa cggtgttttg agctgacttc
     9661 gtcagttcta tccacaacct caaagcactg ttttgagcag tctgcagcta gcttcctagt
     9721 ttgctctttg attttcattg agtattagaa catacaatgg aggtcgtcat ggacaatatc
     9781 atcgatgtgt caattcctgt tgcagaagtg gtggacaagc atccagaagt cttggaaatt
     9841 ctagtggagt tgggttttaa accccttgcc aatcccttaa tgcgcaatac agttggtcgc
     9901 aaggtatcgc tcaaacaggg ttctaagcta gcaggaactc ctatggacaa gattgtacgc
     9961 acactggaag cgaatggcta cgaagtgatt ggattagact aatggcagat gaacggattc
    10021 atgtcctacg ggatattttg ttagaattgc acaatggcgc ctctcctgag tcggttcaag
    10081 agcgctttga tgcgaccttt gcgggtgtct cagccatcga gatttccctt atggagcacg
    10141 agctgatgaa ctcagactca ggtgtcacct ttgaagatgt tatggaactc tgtgatgtcc
    10201 atgccaatct ttttaaaaat gctatcaaag gtgtcgaagt ttcagatact gagcatccag
    10261 gtcacccagt tcgtgtcttc aaagaagaaa atctggctct ccgtgcggcc ttgattcgca
    10321 ttcgtagatt gttagatacc tatgagtata tggaagacga ggaaatgctg gcggagatgc
    10381 gtaagggttt ggtgcgtcag atgggacttg tgggtcaatt tgacatccat taccaacgta
    10441 aggaagaact cttctttcct atcatggagc gctatggaca cgattcacct cccaaagtta
    10501 tgtggggagt ggatgatcag attagggaac tctttcaaac agctctaacg acagccaagt
    10561 cactaccaga agtgtcaatt agcagtgtaa aggaagcttt tgaagctttt gcgacagagt
    10621 ttgaaagtat gattttcaag gaagagtcca tcctcctcat gattctcctt gagtctttta
    10681 ctcaggatga ctggcttcag attgcggagg agagcgatgc ctatggctat gccatcatcc
    10741 gtccgtcaga gaaatgggtg ccagaacgac agagctttat tgaggaaaag attgcagagg
    10801 agcctgtaca gctagatacg gcagaaggtc aagttcaaca agtcatagat acgccagaag
    10861 gccattttac cattaccttt acccctaagg aaaaggaagc tgtgctggac cgccatagtc
    10921 aacaggcttt tggtaatggc tatctttcag tcgagcaggc caatctcatc ctcaatcacc
    10981 tccctatgga gattaccttt gtcaataaag atgatatttt ccagtattac aatgacaata
    11041 cgccagctga tgagatgatt ttcaaacgga cgccgtctca agtcgggcgc aatgtcgaac
    11101 tctgccatcc gcctaagtac ttggacaagg tcaaaactat catgaagggg cttcgtgagg
    11161 gaagcaaaga caagtatgaa atgtggttca agtctgagtc gcgaggtaag tttgtccaca
    11221 tcacctatgc tgcagtacac gatgaagacg gagaattcca aggagtgttg gagtatgttc
    11281 aggatatcca gccctaccgt gagattgata cggactattt tcgtggatta gaataaggag
    11341 aaaaaatgag ttacgaacaa gaatttatga aggaatttga agcttgggtc aatacccaaa
    11401 tcatgattaa cgacatggcg cacaaggaaa gtcaaaaagt ttacgaagaa gaccaggacg
    11461 agcgtgccaa agatgccatg attcgctacg agagtcgctt ggatgcttat cagttcttgc
    11521 ttggtaagtt tgaaaacttc aaagcaggca agggattcca tgatttgcca gaaggcttgt
    11581 ttggtgagcg aaattattaa acgagaaaga ttcttgattt ttcactaaaa tcttgataga
    11641 atgtttatgt taaatccttg tcagagcagg gattttttat tgaaaggatt ttatcatgtc
    11701 aaagaaactc aatcgtaaaa aacaattacg aaatggcctc cgtcgcgcag gtgccttttc
    11761 aagtactgtg actaaggttg tagatgagac aaaaaaagtc gtgaagcgtg cagaacagcc
    11821 agcaagcgca gctggtaagg ctgtttctaa aaaagttgaa caagcagtag aagctaccaa
    11881 agagcaagct caaaaagtag ctaattctgt agaagatttt gcagcaaact tggggggact
    11941 tccacttgat cgtgccaaga ctttctatga tgaaggaatc aagtctgctt cagatttcaa
    12001 aaactggact gaaaaagaac tccttgcctt gaaaggaatc ggcccagcta ccatcaagaa
    12061 attgaaagaa aatggcatca agttcaagta atttttcttg agccttgcat ttccgagaaa
    12121 aacttgctac aatagagcca ttagaggtgt tttgaatccc acattttaca gaaagtggcg
    12181 gcgctgagaa gtccacaaat gtgtcaaaac tggttgctaa tgactgaaaa aatgaaatat
    12241 ttctgtcttt ttattttaaa gactaaagat gcgggcttgg cccgaaattg ggtggtaccg
    12301 cggataaaca cattcgtccc tgtcatgtag atggcagggc ttttcttttg tgtcttagtc
    12361 aaaggaggtt gttataaaac aatcatttaa aactaataaa ctatattatg gttttcctgt
    12421 ttttatttta ggatatcaag atcagaattt tagctataac atcatgacct gtagttcctc
    12481 ttatagtcta ggagattggg ttgtgattgg agtcgttgcg agagagaatg ccgcagagca
    12541 gatcaaacaa tatcaaaaat ttactgtgaa tatttctgat gaaacttcta tgcttgcgat
    12601 ggagcaggct ggttttatca gtcatcagga gaaattggaa cgtttgggag tgcattatga
    12661 aatttctgaa cgaactcaga ctcctatttt agacgcctgt ccacttgttt tagattatcg
    12721 ggtagatagg attgttgagg aatacggtat ttgccacatc tttgccaaga ttcttgagcg
    12781 acttgttgcc ccagaactcc tggatgaaaa gggacatttt aaaaatcaac tgtttgccca
    12841 acctatttca tgggagatgg atatcagcgc gtttattgct atctggacaa gcgtgtagat
    12901 atgaagggca gtttcatcaa aaaagcgagg aagaaggatg gcaagaactg agctgccaga
    12961 taaaatcgaa acagaacgtc tcgttttacg agtccgtact gtggcggatg ctgaggatat
    13021 ctttgactat gctagtttgc cagaggtcgc ctatccagca ggttttcctc cagtcaagac
    13081 cttggaagat gagatttatt atctggagca catttttccg gagcgtaatc aaaaggaaaa
    13141 tctcccagca ggctacggga ttgtcgtcaa aggaacggat aagatcgttg gctctgtcga
    13201 tttcaaccat cgccatgaag atgatgtgct ggaaatcggc tataccttac acccagacta
    13261 ttgggggcga ggttatgtgc cagaagctgc gcgtgccttg attgacttag cctttaaaga
    13321 tttgggtctt cacaagattg aactaacttg ctttggatat aaccttcaaa gtaaacgagt
    13381 cgcggaaaag cttgacttta ccctcgaagc tcgcataaga gaccgcaaag atgctcaagg
    13441 caactgctgt gatgatttaa gatatgcctt gctgaagagt gaatgggagg tgatttgatg
    13501 catcttttca tcattggtgc tccagcatca ggaaaaatga ccattggtca agaattatct
    13561 cgactgacgg atgctaccct attttataac catcaagcca tcgattttgc actagaaatc
    13621 tatcaggact atacagagga aatgtgggaa tttgttcgtg gaatcacttt ttcattcctt
    13681 ggagcgagtg caagaaatca gcgatcagta attttaacag atgtaattga tttttcaaat
    13741 cagtatcatc tgatatattt aaagcaaatt cagagtttgt tggatgatta tcatcaagag
    13801 attctttttg ttgagttgga aacaagtctt gaagagtgca tacgtcgaaa tcgaacggag
    13861 aatcgattaa agtacaaacc cttaaaacga catattgagg tatctgaaag agaaattata
    13921 gagaccgctg aaatacttca attaaattcc caatatcaac cgaatgagtt gcaccactac
    13981 tttaaaataa ataatacgaa tttgtctgca gaagaagctg ctaagcaaat tcaaaataaa
    14041 ataaacaaaa tagagaaagg acacacacat gtctaaagaa ctttcatcta aatacaatcc
    14101 agccgaggtt gaggctggtc gttaccaaaa atggcttgat gctgatgttt tcaagccttc
    14161 aggcgatcaa aaggctaagc cttattcaat cgttattcca ccaccaaacg ttacaggtaa
    14221 acttcacctt ggtcacgctt gggatacaac tttgcaagat attatcatcc gtcaaaaacg
    14281 catgcaaggt tttgatacgc tttggcttcc aggaatggac cacgctggta ttgcgactca
    14341 ggctaaggtt gaggagcgct tgcgtggtga gggcatttcc cgctatgacc ttggtcgtga
    14401 gtctttcttg acgaaagtct gggaatggaa agacgaatat gccactacca tcaaggaaca
    14461 atggggcaag atggggctct ctgtagacta ttctcgtgag cgtttcactc ttgacgaagg
    14521 tttgtcaaaa gctgttcgta aggtctttgt ggacctttac aagaaaggct ggatctaccg
    14581 tggtgagttt atcatcaact gggacccagc agctcgcaca gccctttctg atattgaggt
    14641 gattcacaag gatgtggaag gtgccttcta ccacatgaat tacatgctgg aagatggttc
    14701 acgcgccctt gaagttgcta caactcgtcc tgagactatg tttggggacg ttgcggttgc
    14761 ggttaatcca gaagacccgc gctacaagga cttgattggt aaaaacgtca tccttccaat
    14821 cgctaataaa ctcatcccaa tcgttggaga tgagcacgca gatcctgagt ttggtactgg
    14881 tgtcgtgaaa atcacacctg cccacgatcc aaatgacttc ttggttggcc aacgtcataa
    14941 cttgccacaa gtcaacgtca tgaacgacga cggaactatg aatgagcttg cctttgaatt
    15001 ttcaggcatg gatcgttttg aagctcgtaa ggcagtcatt gctaagttgg aagaaatcgg
    15061 tgcccttgtc aaaatcgaaa aacgtgtcca cagtgttggt cactcagaac gtacaggtgt
    15121 cgtagttgag ccacgcttgt ctactcaatg gttcgtcaag atggaccaat tggctaagaa
    15181 cgccattgcc aaccaagaca cagaggacaa ggtcgaattc tacccacctc gtttcaacga
    15241 taccttcctt caatggatgg aaaatgtcca cgactgggtt atctctcgtc agctttggtg
    15301 gggtcaccaa atccctgcct ggtacaatgc tgatggtgaa atgtatgtcg gcgaagaagc
    15361 tccagaaggt gacggatgga ctcaggacga agacgtcttg gatacttggt tcagttctgc
    15421 cctctggcca ttttcaacca tgggctggcc tgaagtcgac tcagaagact ttaaacgtta
    15481 tttcccaact tcaaccttgg taacaggtta cgacatcatc ttcttctggg tgtctcgtat
    15541 gatcttccag tcattggaat tcacaggccg tcaaccattc caaaacgtcc ttatccacgg
    15601 tctcattcgt gacgagcaag gacgcaagat gtctaagtct ctcggtaacg ggattgaccc
    15661 aatggatgtt atcgagaaat acggtgccga tgcccttcga tggttccttt caaacggttc
    15721 tgcgccagga caagacgtgc gtttctctta tgagaaaatg gatgcttcat ggaactttat
    15781 taacaagatt tggaacattt ctcgctatat cctcatgaac aatggaggtt tgacgctgga
    15841 tgtggcgcat gacaatgtca caaaagttgc aacaggtgag gctggtaatg tgacggaccg
    15901 ctggattctc cacaatctca acgaaaccat tgcaaaagtt actgaaaact ttgataagtt
    15961 cgagtttggt gtggctggtc atatccttta caacttcatt tgggaagaat ttgccaactg
    16021 gtatgttgag ttgaccaagg aagttcttta cagcgacaat gaagacgata aggtaattac
    16081 tcgatctgtt ctcctctata cgctggataa aatccttcgt ctccttcact caataatgcc
    16141 gttcgtgaca gaagaaatct ttggtcagta cgctgaaggc tctatcgtga cagcagcata
    16201 cccaactgtc aacccagcct ttgaggacct tgctgcccac actggtgtgg aaagtctcaa
    16261 agacttgatc cgtgccgttc gtaatgcgcg tgcggaagta aatgtagcac caagcaaacc
    16321 tatcaccatc cttgttaaga caagcgatag cgacttggaa gccttcttta acagcaatgt
    16381 caactatatc aaacgcttta caaatccaga acacttggaa atcgcatcaa ccatccctgc
    16441 acctgaactg gctatgtcaa gcgttattac aggagccgaa atcttcttgc cactggtaga
    16501 cctcttgaat gtcgaagaag aattggcacg tctggaaaaa gaacttgcca aatggcagaa
    16561 agaactcgac atggttggca aaaaactcag caacgaacgc ttcgtcgcca acgctaaacc
    16621 agaagttgtc caaaaagaaa aagacaaaca agccgactac caagccaagt atgatgcgac
    16681 cgtagcacgt attgatgaga tgaagaagtt ggtgaaatga tgttaaaaac ctaaccctat
    16741 cgggttgggt tttacatttg ataatgttat aataaaaagg agaaacttta ggagaatact
    16801 atggggaaaa ttgttgctat tgatttattt aacggtgcag gtggcactac aagtggcctt
    16861 aaaaaatcag gcatagatgt tcaagttgct gttgaaattg attccgtagc tgttaaaact
    16921 tataagttaa ataatcctga ggtgtctgta atagatatgg agtaaataaa acttcaattt
    16981 tacaagcttt atatggttct ccagccaata aaagtgtgtc tgaatattgg tttagtacaa
    17041 atgttgatca aatagatgaa gtggatggga aacaatgttt aatctattca tattataacg
    17101 ttaaagcttc tagaaatgta gaagttctta aaggccgttc tggaacaaaa aaaggattag
    17161 attattggga accatatgct cctcaaaaac aatatgagat ggaaagatta cccaaaaata
    17221 aatatattgg aagttcttcg acagacagat gggatggcat tgaaaaaaat gttgtctttt
    17281 gtgattgtaa agaatatgtt tctgcttttg atttattttt ctatcactat aattttaaaa
    17341 aaatttctac tcaacgtagt aaacaagatt ttataagatt acgatctaaa ccagttgctg
    17401 atattttaaa gaataataca agtagttata cgcgttataa aaaggaaatg gttatagata
    17461 atgttaaagt tgatgataaa gtttgtgaaa ttattagtga aataatggat gaatcttata
    17521 cagacattca aattttaaca cataagttgt attcaaaagg tgatgatata aaagcttcca
    17581 aaactatttg gatgaaaaaa tctggaaaag aatattccga ggcttttgca ggaacaggtg
    17641 aggctagaat tattttgtta gtaaatgata tagtaaatgc gcaatcaaat tcattaatat
    17701 taatagatga acctgaaatc tcacttcatc cgagtgcaat ctataaattt aaagagtttt
    17761 tacttcaaga gtgtttaaat aaaaaacatc aaattattat cactacacat tctacacaac
    17821 ttataaaaga ttttcttaga gaagccgtga aacttttagt gaaaaacgga gaaaaggtag
    17881 atgttattga aaatattgat tatcaggatg cattttttga attaggtgat gtgtatcatt
    17941 ctaggaagat gatttatgtt gaagatagac tagctaaata tattctagag tttgttatca
    18001 ctcattcagg tagtgagaat cttaaacaga atttagtagt gagatatatt cctggtggag
    18061 caaatcaaat aatttgtaat aatattttaa actcatcgta tttagattcc gataaccatt
    18121 atttttggtt tgatggagat caaaacacta atgttagtga atcaaataat ttaatgaact
    18181 atcttgaaaa tggtgttgtt atatcagata aaattcctga atcagataat aaaaatcttg
    18241 atgatattat aaaattgata acgggatgtc caattaaatt taatgtttca ggtaataaag
    18301 ggcaaaaaaa taatattgaa ttaattgcga aacaaagaag ctttatagat tattgggcta
    18361 aatacgtttc ttatcttcct ttcccaaccc cagagttttt tttagctaat ttgtgtaaca
    18421 gcgtagatag ggaaggttat gatttttcta aagatggcaa cggaaaagaa tattttagaa
    18481 aaaaaactca agtagcgtta ggaatagaga atataacttc tgaagatatt ttccaggagc
    18541 aaagaagagc tgtttcaaaa atacagccag aatcatcaat gtttcagtgt attaaagaaa
    18601 aattagaggc attgttctaa ttccttagat taggtactac ataacaaatt ttttaaattc
    18661 aaacccgcac caaaaacaac attgcaactt tcttctcagg taatgtgttg ggatttgaac
    18721 agaccaacga gttcatagag gtgtatgcca atgagtttga taagtatgcg cgtcagactt
    18781 attagttcat ttatccagat atatctcgat aatcatatta tttagtcaaa gaacatccca
    18841 tatgagggca tgaaatgcta agtttagctt gctcactatt aagatgaagt atatatattt
    18901 catagaactt attgtgaagg atttttataa ttttcgccaa ttccataccc atttcaccat
    18961 ttaccgatga cacagaaaaa caattgaaag gatatttcta tgcaaccaac ttacaacatt
    19021 gacaatccaa acttgtctta tgaagcgaag cgtgatttat ggcggatagg ttttggtctg
    19081 cagaaagttg acaatctagt gccatcagcg tatatggaat ctttggctga gaaacagtcc
    19141 cggggagaac tgacttatga gcaggtttat gaggatgcaa cggcttatca ccatactatt
    19201 gatgcaagta cggaagaggc agacttggtt tctctacgta ttgtagaact attgtctcga
    19261 agaggcttta gctttagtcc tgcgacctta cttgctattc ataaggagtt gtttcaagat
    19321 atatttgaac cctctattcc ggtggggcaa tttcgtcaga ccaatatcac aaagaatgaa
    19381 cctgttttga atggtgaaag tgttgtgtac tctgattact ccatgattca aatgacctta
    19441 gattatgatt ttaatcagga aaaacaagtt gcatatgcga cactaactca ggcggatgtg
    19501 gttaaacaaa tccagcattt tatttcagga atctggcaga ttcatccatt tcgcgaagga
    19561 aacactcgga cagtaacggt ctttttgatt cagtatcttc gtgagtttgg ttttgatatt
    19621 gataatacac catttcagca acattccaaa tattttcgtg atgccttggt attagataat
    19681 gcaaagattt tacagcgacg tcctgagttt ttaacagctt tttttgaaaa tctcttgctc
    19741 ggtggtcaaa atgatttgtc ttcagaaaaa atgtatctag atttagacct tgatttttca
    19801 taatccaaat actgagtaaa cattgaattt taggcaaaaa tgaagtaaat attctcacaa
    19861 gaaaacgtat atcatcaaag ttttaggtgt actgacccca aacagttaga caattaattt
    19921 atccgaagga tttagttctg tattgcacag gactaagtcc ttttagtttt accttaattc
    19981 gtttattgtt gtagtaatca atatagtcta caatagcttg ttccaattgc ttaagcgact
    20041 gaaacgactt ctcataaccg taaaacattt ccgatttcag aatcccaaag aaagattcca
    20101 tcataccgtt gtcttggctg tttcccttgc gtgacatgga tgcttgaact cccttactct
    20161 ctaggaaccg atgataagaa tcgtgtcggt attgccagcc ttggtcacta tggagaatcg
    20221 tattctcata gtgcttctct gtgaatgcct gttccaacat tgtttgtact tgttctaagt
    20281 tgggtgaagt tgaaagatta taggcgataa tttcgctatt aaagccatct aaaactggtg
    20341 ataagtaaag cttttgagta cttgctggaa tggcaaattc tgtcacatct gtgtagcact
    20401 gttccattgt tttagagcct tcaaattggc cttgaatgag attctctgcc ttcttgccaa
    20461 cgtctccttt atgagaagaa tattttcgtt tctgtcgcat tttagcttgt aaattgagta
    20521 cttcatcaag tgttgaactc ttttatgatt taccagataa ccacgatttc ttagttctaa
    20581 ataaatccga cgataaccat aatttccctt gtgttcgata aagatggatt gaatttcagc
    20641 tttaagctct tggtcct
//
LOCUS       DAYYYC010000038        20370 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.038, whole genome shotgun sequence.
ACCESSION   DAYYYC010000038 DAYYYC010000000
VERSION     DAYYYC010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20370
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.038"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..662
                     /locus_tag="ACHBV5_001468"
     CDS             <1..662
                     /locus_tag="ACHBV5_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HFM9967239.1"
                     /translation="GILLSLMKYCTIFDDKKLANFIKNNINDAYSLLESEDNGDIYSN
                     NFAHGRSGAAYVLKAYTDIFGDSRYQNHLQKFSDGISELLEEKLSSFSKLDNLGLSWC
                     DGVSGLILYLCLIDKERYSEIIYKSQLEMVQQYEAMGTSFCHGLSSLLQTTIYNKNQK
                     VEQFIKKILLTRSYRNNDRLLQFQGEDGINSYFDFGVGNLGIYWTLLGYTFPFELSKG
                     D"
     gene            664..1902
                     /locus_tag="ACHBV5_001469"
     CDS             664..1902
                     /locus_tag="ACHBV5_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967240.1"
                     /translation="MHIFLKNRAFRQLTVNEWISSFGDTIFYLAFINYVSSYAFAPLA
                     IFLISLSETIPQVLQLFTGVIADFQKNRISKYISILFIKVLLYSGVTLLLTSTDFSLF
                     SVFFICSMNLISDTIGFLAGYMLTPIYIRLINDDMTEAMGFRQSTSSIVRLIGNLSGG
                     VFLGLFSISTLAFVNVLTFLFAFLGSLLIRNRLKKEEEKIEVPPYVGMSSFFQHLKES
                     MKLLMTMEDVMVLLWILSISQAVLMMVEPVSAILLIHHPFMGLSTGQSLAILIMISLL
                     HVILGGLLSGFLSKKISIRLNIYWSLLMESLIVIDFLRGSFLLILLGSAGDAFSAGVL
                     SPRLQAMIFGIIPEELMGSVQSSINVINLLIPAVLSLALVFLATSAGLEVVAFALIIL
                     LLIAAYLVHQMKNLPNQEEV"
     gene            2091..5237
                     /locus_tag="ACHBV5_001470"
     CDS             2091..5237
                     /locus_tag="ACHBV5_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000621470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140658 - ATP-dependent chromatin
                     remodeler activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2-related protein"
                     /protein_id="HFM9967241.1"
                     /translation="MIRTEVTSMTVPDRLPARMRMDGRSIFQQIKNYFDTENKEYFKH
                     PNTYDGISMHLEPNILTSMEHFDLTGFHCECKDFQNQGVCKHWVAMDLYFRSLPQAIQ
                     ERIGKASHKPSFASQLIPTLPSEELQDELVEEKATAPSLALHGQVEIRNHSLAWTLKL
                     QVEQAPRAYVIKDIAHFIFLIFQKEDYFVSQKIGTIRLSLNQFNQASQNLLLYIKKYF
                     IDRNEHSYFNFSYGINPRDYGRYLETPVSYLNDLVPLFQALDVFQYVTSKAEYPLIFL
                     DDSPFIPEEEIFKVVKSNNHYEIINTAYFGFIIQEKLWIRHNHFHIIKEEHRYFLDKL
                     ATWIYHYQENSPLIFSKENKAELMQVCNIISNYVPISIPDELQIHDFIPTFAFSKTRN
                     EIALNMVWSFGEKQVHSKQDLLTLPYTYQASKARKIYHQLLSAGFKEEFHSLSKIKIV
                     DFFLKELPRFRTLGQVQLDESLEKLLVEDPAVIDIFDDESFLSVQFDFSMISEDEVEK
                     AIQALWNQESHYQTKQGKVLVFDDESLKVAQSLQDLRAKFSDGKIKMHKSRAFSLSET
                     FKDNEHVNFSRDFKKMAYDLTHPEEFDIKPYEVKAKLRSYQKEGVKWLSMLDHYHFGG
                     ILADDMGLGKTLQTITLLEANLKPDQKALILAPASLLYNWKEEFRKFVPHKQVEVAYG
                     SKTERIKQIEKSATITITSYPSFRSDLEHYQKQSYDYLILDEAQMIKNSQTKTAQALR
                     EFDVKTCYALSGTPIENRLEEIWSIFQIVLPGLLPSKKEFSKLSPQLVAKLIQPFVLR
                     RKKDEVLTELPELSEHLYSNELSSSQKTLYLAQLRRMQEMVSGASAYEIKRHKIEILA
                     GLTRLRQICNTPALFLEDYKGDSGKMDSLFELLDTIREKGSRPLIFSQFTSMLDLIEQ
                     ELEKKEMSHFKITGQTPSDKRQEMVNLFNQGEKDCFLISLKAGGTGLNLTGADTVILC
                     DLWWNPAVEMQAIGRSHRLGQTKQVDVYRLITLGTIEEKIQELQESKKELFNTVLEGQ
                     ESRSNLSVDDIKEILGVE"
     gene            complement(5674..8010)
                     /locus_tag="ACHBV5_001471"
     CDS             complement(5674..8010)
                     /locus_tag="ACHBV5_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFM9967242.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFGVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            8143..8892
                     /locus_tag="ACHBV5_001472"
     CDS             8143..8892
                     /locus_tag="ACHBV5_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFM9967243.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            complement(9185..9799)
                     /locus_tag="ACHBV5_001473"
     CDS             complement(9185..9799)
                     /locus_tag="ACHBV5_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HFM9967244.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIQRL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(10614..10883)
                     /gene="rpsO"
                     /locus_tag="ACHBV5_001474"
     CDS             complement(10614..10883)
                     /gene="rpsO"
                     /locus_tag="ACHBV5_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFM9967245.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            complement(11024..11653)
                     /locus_tag="ACHBV5_001475"
     CDS             complement(11024..11653)
                     /locus_tag="ACHBV5_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFM9967246.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADEFDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            11892..12255
                     /locus_tag="ACHBV5_001476"
                     /pseudo
     CDS             11892..12255
                     /locus_tag="ACHBV5_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397621.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12512..12835
                     /locus_tag="ACHBV5_001477"
     CDS             12512..12835
                     /locus_tag="ACHBV5_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HFM9967247.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            12893..14836
                     /gene="thrS"
                     /locus_tag="ACHBV5_001478"
     CDS             12893..14836
                     /gene="thrS"
                     /locus_tag="ACHBV5_001478"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFM9967248.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(14885..15859)
                     /locus_tag="ACHBV5_001479"
     CDS             complement(14885..15859)
                     /locus_tag="ACHBV5_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HFM9967249.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(15852..16529)
                     /locus_tag="ACHBV5_001480"
     CDS             complement(15852..16529)
                     /locus_tag="ACHBV5_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFM9967250.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            16685..17758
                     /locus_tag="ACHBV5_001481"
     CDS             16685..17758
                     /locus_tag="ACHBV5_001481"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HFM9967251.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            complement(17849..18151)
                     /locus_tag="ACHBV5_001482"
     CDS             complement(17849..18151)
                     /locus_tag="ACHBV5_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967252.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(18220..18657)
                     /locus_tag="ACHBV5_001483"
     CDS             complement(18220..18657)
                     /locus_tag="ACHBV5_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFM9967253.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            complement(18733..19575)
                     /locus_tag="ACHBV5_001484"
     CDS             complement(18733..19575)
                     /locus_tag="ACHBV5_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HFM9967254.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            19687..20337
                     /locus_tag="ACHBV5_001485"
     CDS             19687..20337
                     /locus_tag="ACHBV5_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFM9967255.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
BASE COUNT         6268 a         4455 c         3744 g         5903 t
ORIGIN      
        1 ctggtatcct actcagtttg atgaaatatt gtaccatttt tgatgataaa aaactagcaa
       61 attttatcaa gaacaatata aatgatgcat atagtttatt agaatccgag gataatggag
      121 atatatattc taataatttt gctcacggac gttcaggtgc tgcctatgta ttaaaagcct
      181 atactgatat ttttggagat agtcgctatc aaaatcattt acaaaaattt tctgacggga
      241 tatctgaatt actagaagag aaactttcaa gcttttctaa attagataat ttaggtcttt
      301 cttggtgtga cggagtttca ggattaatat tgtatctttg tttgattgat aaagaaagat
      361 actctgagat aatctataaa tcacaacttg aaatggtgca acaatatgaa gcaatgggaa
      421 ctagtttttg ccatggttta agtagtttat tgcaaacaac aatatacaat aaaaatcaaa
      481 aggttgaaca gttcataaaa aaaatcttat tgactcgttc ttatcgtaat aatgatagat
      541 tattacaatt tcaaggggaa gatggaataa acagttattt tgactttggt gtgggaaatc
      601 tgggtattta ttggacttta ctcggttata cattcccatt tgaattaagt aaaggagatt
      661 aatatgcata tttttcttaa aaatcgagct tttcgtcagc taacagtaaa tgagtggatt
      721 tcaagttttg gagatactat tttttactta gcttttatca attatgtctc ttcttatgcc
      781 tttgctccct tagctatatt tttgattagc ctatcagaaa ccattccaca ggtcttgcaa
      841 ctttttactg gagttatagc tgattttcaa aaaaatcgaa tcagcaagta tatttctatc
      901 ctctttatca aggtcctcct ttattctgga gtgactttgc tcctgacaag taccgacttc
      961 tctctctttt ctgttttctt tatttgcagc atgaacttga tttcagatac gattggtttt
     1021 cttgcaggat acatgctgac accgatttac atacgactaa taaacgatga tatgacggag
     1081 gctatgggtt ttaggcagtc cacgagttcc attgtacgtt tgataggtaa tctcagcgga
     1141 ggagtatttt taggactgtt tagcatttct actctagctt ttgtaaatgt tttaaccttt
     1201 ttatttgcct ttctaggaag tctacttatc cgaaaccgct tgaaaaaaga ggaagaaaaa
     1261 atcgaagttc ctccttatgt aggaatgagt agctttttcc agcatttgaa agagtcaatg
     1321 aaattattga tgactatgga agatgtcatg gtcttgcttt ggattttgtc cattagtcaa
     1381 gctgttttga tgatggtaga gcctgtcagt gcgattctac tgattcacca tccttttatg
     1441 ggtttgtcaa cagggcaaag tctggcaatt ttaataatga taagccttct tcatgttatt
     1501 ttaggtggac ttctgagtgg atttctatct aaaaaaattt ctattcgcct gaatatttat
     1561 tggagtctat tgatggagtc tctcattgtt atagattttc tacgtggaag ttttttactt
     1621 attttactag gaagtgcggg tgatgctttc tcggcaggag tattgagtcc tcgcttgcaa
     1681 gccatgattt ttggaatcat tcctgaggag ttaatgggat cagttcaatc atccatcaat
     1741 gttatcaact tacttatccc agctgtccta tcccttgctc tcgtatttct tgcaacaagt
     1801 gctggtctgg aagttgttgc ttttgctctt ataattttac tacttatagc agcctatcta
     1861 gttcaccaga tgaaaaactt accaaaccaa gaagaagttt agctagaatg ttatggataa
     1921 gtcagttttc acttgatagt ttctatggaa tcgtaatctc cttgtaattg attgtcgata
     1981 ttacatacaa ctatcttgca actacaaatg tttccaatcc ctatcaagat gcaatttatg
     2041 taagataaat ctattctttt cctataaatt ctgataagat agagaaaaga atgattagaa
     2101 cagaggttac ttcaatgacg gttcccgata gactacctgc tcgtatgaga atggatggcc
     2161 gctctatttt ccaacagata aaaaactatt ttgatactga aaataaggaa tattttaagc
     2221 accccaatac ctatgatggt atttccatgc atctggagcc caacatcctg accagtatgg
     2281 agcacttcga tttgactggc tttcattgcg aatgtaagga tttccaaaat cagggagtct
     2341 gtaaacactg ggttgccatg gatctttatt ttcgtagtct cccccaagct attcaagaac
     2401 gcattggtaa agcgagtcat aaaccaagtt ttgccagcca actgattcct accttgccat
     2461 ctgaagagct ccaagatgaa ctggtagaag aaaaagctac ggcgccttca cttgcccttc
     2521 atggacaagt cgaaatccga aatcatagcc tagcctggac cttaaaatta caggtagaac
     2581 aagctcctcg tgcctatgtt atcaaggata tagctcactt catttttctc attttccaaa
     2641 aggaagatta ctttgtttca cagaaaatcg ggacaatcag attatccttg aatcagttta
     2701 atcaagcatc ccaaaaccta ctcctctata ttaaaaaata ttttatcgat agaaatgaac
     2761 attcttattt caacttcagt tatggcatta accctagaga ttacggacgc tatttagaga
     2821 ctcctgttag ctatttaaac gacctcgtcc cactttttca agctttggat gtcttccaat
     2881 atgtaacctc aaaagccgaa taccctctta tattcttaga tgatagtccc tttatcccgg
     2941 aagaggaaat ttttaaagtt gtcaaatcta ataaccatta tgaaatcatc aatacagctt
     3001 attttggttt cattattcaa gaaaaacttt ggattcgaca caatcacttc cacatcatca
     3061 aagaagaaca ccgttacttt ttggataaat tagctacttg gatctatcat tatcaagaaa
     3121 attctcctct tatcttttca aaagaaaata aggctgaact catgcaagtc tgtaatatca
     3181 tctcaaacta tgttcctatc agtatcccag atgaattaca aatccatgac tttatcccca
     3241 cctttgcctt ctccaagact agaaatgaaa ttgcccttaa tatggtgtgg tcctttggag
     3301 aaaaacaagt ccattctaaa caagatctcc taaccctccc ctatacttac caagctagca
     3361 aagctagaaa aatctatcat caactgcttt ctgctggttt caaagaggaa tttcatagtc
     3421 tttccaaaat caaaatcgtt gatttcttcc taaaagaact cccccgtttt cgtactctgg
     3481 gtcaagttca actagatgaa tcgcttgaaa aactcttagt agaagatcct gctgtcattg
     3541 acatttttga cgacgaaagc ttcctttcag ttcagtttga tttttctatg atttcagaag
     3601 atgaggttga aaaagctatc caagctttat ggaatcaaga aagccactac caaaccaagc
     3661 aaggaaaggt tctagtcttt gacgatgaaa gtctcaaggt tgctcaaagt ctccaagatc
     3721 ttcgcgctaa attttcagac ggaaaaatca agatgcacaa atctcgtgcc tttagccttt
     3781 ctgaaacctt caaagacaat gaacatgtca atttttctcg tgatttcaaa aagatggctt
     3841 atgacctgac ccaccctgaa gaatttgata tcaagcctta tgaagtcaag gccaaactcc
     3901 gctcctatca aaaagaagga gtcaagtggc tgagtatgct ggatcattat cattttgggg
     3961 gaatcctggc agacgacatg ggtctaggga aaaccttgca aaccatcact cttctggaag
     4021 ccaaccttaa accagaccag aaagctctta tcctagctcc agccagcctt ctttataatt
     4081 ggaaggaaga attccgaaaa tttgtgcctc acaaacaggt tgaagtagcc tatggtagca
     4141 aaactgagcg tatcaaacaa attgaaaaat ctgctactat cactattaca agctatccat
     4201 cttttcgatc tgaccttgaa cattatcaaa agcagtctta cgactacctc atcctagatg
     4261 aagcacagat gataaaaaat agtcagacca aaacagcaca agctttaaga gaatttgatg
     4321 tcaaaacctg ctatgcccta tctggaactc ctattgaaaa ccgtctcgaa gagatttggt
     4381 ctattttcca gatagtatta ccaggtctcc taccaagtaa aaaggaattt tcaaaattgt
     4441 cacctcaact cgttgctaaa ctgattcaac cttttgttct gcgtaggaaa aaagacgaag
     4501 ttctgacaga attgcctgaa ctgagcgagc acctctacag caatgaactc agcagttcgc
     4561 aaaaaacgct ctatctagct caacttcgac gcatgcaaga aatggtttca ggagccagcg
     4621 cctatgagat taaacgtcat aaaattgaaa tcttagcagg actgacccga cttagacaaa
     4681 tctgtaatac ccctgctctc tttttagaag actacaaagg ggatagtgga aaaatggaca
     4741 gcttattcga gctcctagac accattcgtg aaaaagggtc acgaccactt atcttttcac
     4801 aattcacctc tatgcttgat ctcattgagc aagaactaga gaaaaaagaa atgtctcact
     4861 ttaaaataac aggacaaaca ccttcagata aacgtcaaga aatggtcaat cttttcaatc
     4921 aaggggaaaa agactgcttc ctcatttccc taaaagcagg tggaacagga ctgaatctaa
     4981 caggagctga taccgtcatc ctctgtgacc tctggtggaa tccagcagtt gagatgcaag
     5041 ccatcggccg aagccaccgc cttggccaga ccaaacaagt cgatgtctat cgccttatca
     5101 cacttggtac catagaggaa aaaatacaag aactccaaga aagtaaaaag gaactcttca
     5161 acaccgtcct tgaaggacaa gaaagcagaa gcaatctgag cgttgatgat attaaagaaa
     5221 tcttgggtgt tgaataaacg aaaaagaact agagtaacca cacttagtgg atttatctag
     5281 ttctttttta ggttctagac tttccttgcc atcctatgag ctctatacgc cttaccatca
     5341 cgtttctgtt cgtttagata caatttcgcc acccctttat ctgacagttt ttatactatc
     5401 aaactaggga gctgaccaca agttgctcaa agtaccgctt tgagattgtg gatagaacgg
     5461 acctggtttg aagatatttt cgaagagaat tatttcttgc atcagacttc aaatagtcta
     5521 actacagata tttgaatcta ttacctcaat ccaagcaggc ttgagaatca ctcttgggtt
     5581 caccgataga taatagacac gtaggccttg cacatcagat ctacgataga tccatcgtat
     5641 aaaaaactgc aatccacaga ttgcagtctt tctttatttt ctagcttgat agcgactagt
     5701 caggatgaaa atcactgtaa agaccaacat catgacacca taaacaggta atgtttgtcc
     5761 tgttaaggtt gcaatttcaa gcagtttttg aattcttggg aagagagctg tggctaggaa
     5821 gcctcctact gaccagacaa tcaataggac tcgccataga gtgaatggca tgcaggctct
     5881 aaatacggat aagaaaccaa ttgaccccaa gagataatag aggagagttg agatttctaa
     5941 ctcagaccaa ccttgactcg ttccaaagat tttcacaaaa agaacgccaa acacgaccat
     6001 gagggcactt ggtagggcac gaagcatgga tcttctgagg aagtttggct cgacaggttt
     6061 gatatttcgc tcaaaagtca gaacgaatgg tgggaaacct tccacaaact ggtcaatcat
     6121 ggtaatctgg atcggaatga agggaaaaat caaaatccac tctgaccgac ctagtaaagc
     6181 actggcaata cagatgactg ctaacaggaa ggaatagatg gtctttatca agaaaatcgg
     6241 ggcgatgtgg gcaatgttat tgaccacgcg acgaccctcg aagagaatct caggaacatc
     6301 attaaagtct gagttcaaga gaaccagatt ggcaatctga cgggttgctg gatccccctc
     6361 cgccatcacg atagaacaat ccgcctcacg aagggccaag atatcattaa ccccgtcccc
     6421 tgtcatagcc gttgtatgac ccgctttttt caacgtttgg atgatgagtt tcttttgatg
     6481 aggggaaaca cgtccgaaaa tagctgtctc ctccgccatg gccatcaatt cctcatcggt
     6541 gatttttgag caatctacat agctgtgata gtccgcaaaa ccagccttct gggcaatgct
     6601 ggacaccgta actggattgt caccagagat aatcttgagt cccacctcct gagaacggag
     6661 atagtccagc gtctctgctg ctccctctcg aatggggtcc aagatttcca gcaaggctag
     6721 agcctgaata tcagatggtt tctgtggttt gtgatggtct aatttctcct gactgagagc
     6781 taagaccaag acacgtgatc ctctctccaa ggcctccctg gcttctggga cttcagaatc
     6841 cagcaacatc tcaggtgccc ctaagaaaac tgtccccaag ccttctaact ccatagcccc
     6901 ccacttgcgg tcgctcgaga agggaagatt ggaaatcata ggataagcaa catctcccac
     6961 aaaacgctgg cgaatggctt gggcagttgg attcttatcc tcactatggg ccatgtagct
     7021 agtcaagatg ctggcaatag cctcttcacc gtaagtttcc gtcagtggaa gaacagcctc
     7081 cacctgcatc tttccttggg tgatggtgcc cgtcttgtcc agacagagca tatccacgcg
     7141 cgccaaggtc tcaacagagt acatctcctg caccaagacc tttttcaaac ctagcttaat
     7201 cactgcagtc aagagcgaag taatggtcaa aagggcaatt cccttaggca acattcccaa
     7261 aagagctgtc gacgagttta caacagatga cttgagaggc aggcctttta aaagcaaggc
     7321 ttccagcaag agagccagac caaagggaat gataatcttc ccagtaaaac cagccaactt
     7381 gtccagcgat ttcatgatac gggagttgat gggtttaacg gtcttagcct caagcatgag
     7441 tttggcagca tagttgtctg caccgacatg gtgaacttga gataaaactg acccactggc
     7501 taggaaactt cctgacaaaa gtaagccgtc aacttccttt tgcaccaaat cactttctcc
     7561 cgttaacatg gcttcattga cttccgcaaa gccttccaaa accaaggcat cactaggaat
     7621 ctgctctcct gcagacaaac gaatgacatc tcctagcact aattcttcag gattaagagc
     7681 aacttcctga ccatcacgga tggttttgac cttttccttg gtcatgagat tgagcttgtc
     7741 caccatgtgt ttggctcgta gctcggtcac aatcccagaa aaagcgttaa agcagataac
     7801 agcaaagaag accagattgc tccaagcctg cacaaaggca agggccaaag caatggcaaa
     7861 gttcaaagcg ttaaaaaggg taaagacatt tcgtttaacg atttgccaag tgctggtact
     7921 ggctgatgcg gtaaagtcat tgaccaaacc ctcagcctgt ctttccttga cttctctttg
     7981 ggttaatccc ataatcttat ttttatccat aaattctatt atatcatttt ttttaacaga
     8041 attctaattt catcccaaat atgcatctag tcaagggaaa agtttgccag ccctcctttg
     8101 ataaggtata ataataacaa gaaaacaatc gaaggagatc gcatgtttta tacttatttg
     8161 cgtggattag ttgtattgct cttatggtcc atcaatggca atgctcacta tcataatact
     8221 gataaaattc ctaatcaaga tgaaaattat attttagttg cgcctcaccg tacctggtgg
     8281 gatcctgttt atatggcctt tgcgaccaag ccaaaacagt tcatctttat ggcaaaaaaa
     8341 gaactcttta ccaaccgtat ctttggttgg tggattcgta tgtgtggcgc ctttcccatc
     8401 gaccgtgaaa atcccagcgc ctcagccatc aaatatccta tcaacgttct caaaaaaagt
     8461 gaccgctctc tcatcatgtt tccaagtggt agccgccact caaacgatgt caaggggggc
     8521 gcagcactga ttgccaaaat ggccaaggtc cgtatcatgc cggttaccta caccggtccc
     8581 atgactttga agggcttgat tagccgtgaa cgtgtcgata tgaactttgg aaatccaatc
     8641 gatatctcag atatcaagaa aatgaatgat gaaggcattg aaacagtcgc caatcgtatt
     8701 caaacagaat tccaacgtct ggacgaagaa acgaaacaat ggcacaatga taaaaaacca
     8761 aatccactct ggtggtttat ccgcatccct gccctcatcc ttgctattat cctcgctatc
     8821 ctaaccatca tctttagctt tatcgcaagc ttcatctgga acccagataa gaaaagagaa
     8881 gaacttgcat agaagaaatg aaccttggcc aaacagctaa ggttttcatt tatatagtag
     8941 attggaacta gaatagtaca cctctacttc taaaacattt ttagaaatcg atttgactgt
     9001 cctgatcgat tttgtcctat tcttatttca ttttactata tttataagaa tcccctaatc
     9061 aaatcaaaag ccactctaca atagagtaac tttaagattg tccatttata ctcaatgaaa
     9121 aagccctctg aaaatcagag agctgatttg agctcaggct aaaatcctag tgaaacaaaa
     9181 aaatctacac gatcagaaaa gtctctatcg tgccattttc atacatgatg tatagtccaa
     9241 gtagaatgaa tactaagggc acaatgattc gctcgtattt ttcaattgtc tcgaatatta
     9301 acggaataga ggataacacc ctactaatct cgcaaaagat aattatgccg attacaaaca
     9361 caagcaaggc cacgagggtc tgtgaccaat ctaacgaagc aaaataaggt atatagatac
     9421 ctaaattatc tccgccagac gcaattgtca gcaatgtaac tgtccaaaac agttgatttg
     9481 ccttgctttg ttctaatctt tgaataattt cttcctcttc ttcttccgca tcttctccaa
     9541 caattgcaaa gcgaatccct aaatagatag ggattaaacc aagcaatcca accatccatt
     9601 cttcaggcac gaaattaacg acataagcag caactaaact cgcccctaca agtaagcctg
     9661 tgcctagata ttgccccgca taaatatgcc atttctgttt attctgtgat agctgtgcaa
     9721 ataaaataat taaaataatt aaataatcga tactggtgga aatataaaca ccaatagcag
     9781 atatgattgt ctgtcccata aaaaaaacct cctgtattag tcagtaataa atcagcagat
     9841 tttaggagag cacaaacaca ttaatttagc tatcgctagt gggtaatgtc gaacgtagga
     9901 aagcatttta ctcctcctca aaacgtagtt acaaagtaat ttctaactgg aattcagtga
     9961 ctacttccat gtaaagtata acatactata ctttactttg taaagagtgg gctcttctag
    10021 ggggcttgca tacagctact cggcttgaaa agccgagtag ctgcgcacct ttatggtgta
    10081 attagctgat accatttgag atttttgtag tctccaaaat tgttaccgat aaaacctcaa
    10141 taaaaaagcc ctctgaagtc agagagctga ttttagcccg ggctaaaatc ctagtgaaaa
    10201 agatgaaact ccttgtgctc atcgaacact gtgtcatttc cctattttca tacggatttt
    10261 tgacaccctt agcatcatga ttcttgctag ataaatcgtt tatagactag gggacgaggt
    10321 gaagatcgta cgaaactttc agtgaaacaa aaaaatctcc acgaagggag aaaagctagt
    10381 ttattttacc ttacagtgct aggaaccgta accgaagatt atacttgagt atagcgaggt
    10441 aaggtgacaa cgcaacaaag ctacccaatt tagagtagct ttattatcaa gatatgctca
    10501 attgaacacg gcctaagcac ttggcaaaaa agataaaatc tcctagaaac tgaagtttct
    10561 tcgtcaattt tcctattttt gctttgtgct tttgacggcc tttgtatctt gaattagcga
    10621 cgaagtccta gagagttgat caactcacgg taacggttaa cgtcgttttt acgcaagtat
    10681 gcaagcaagt tacgacggcg accgattttt ttcatcaatc cacggtaagt agcgtggtct
    10741 tttttgtgtt gtttgatgtg ttcgttaagg tggttgattt cccaagtaag gacagcaact
    10801 tgaacctcta ctgaacctgt atcaccttcg tgacgtgcat attgtgcaat gatttcattt
    10861 tttttctctt ttgagattgc catgatgttt ctccttttta tttggcttca tccgagtgac
    10921 aggttggcat gcctgtaacc aagaagaagt tatttgtctt tacgacaatc cctattttac
    10981 caagatttaa attttctgtc aaacattaat actctcatag ttattatttt tcaagtaaag
    11041 agatacgttc ttttatatga tgaccttttt caagttcatc taccaatcca atagcataat
    11101 ctgcataact aatctggctt attccttttc cattagtagt aaaaatttct cctgctagaa
    11161 tgtagtttcc tgttttttca ccatcgggaa taaaatctac agcaggactg acaaaagtcc
    11221 agttgagatt attttttgta cgaagaagat caaattcatc cgcttgagct tttgctagtg
    11281 acttaaattc ttcaggaaaa tcagacgtat ctaaaagtcg tgtcgttttt gtttcatcta
    11341 tataaagact tcctgctccc cctacaacta gaaaacgtgt ctgtgttcca gcaagaagct
    11401 gattaaatag ttcgattgat ttgctgtgga gcggtagcgt atctggtgta taagcaccaa
    11461 acgctgaaat aacagcatca aatccagtaa gatcatcttt tgtcaactca aataaatctt
    11521 ttttaataat agactcagct tgacttttgt tttcagaacg aacaatagcc gttacttcat
    11581 gtcctcgttt gactgcttct tcaacaattg ctttccccgc ttgtccattt gctgcaataa
    11641 ctgctagttt cattttttat acctctattg ttgtaattat tttagttaca acaaatgtga
    11701 cactcttaat aatcaatatc aatagtcttg cttaattatt atcaaaatat ttctaccaag
    11761 aaaactaact atgattctag tgaaaagaaa aatcttcttt gtcaacaaat ttactttctt
    11821 gttttaaaca tgctataata atcatagcaa gagatctaag ttgtctgttt ttttaaaacg
    11881 aggtgattat catgcgtaga ttctattccc atctccccta ctatctggtc atattattct
    11941 tttattggcc actttatgag ttgttcttgc tagttgtttc tgaccccttt acactatata
    12001 aacaatcttc tcttctttac acctctggta atcttgattg tatcgttact ctatagctac
    12061 cgtttccgtt tctcactttg atggttagtt ggtaacggac tgctctttta ctttactatc
    12121 ataacctttg gtgagtttat actaatttac ttgctaatct atgaaacagt tgctctggtg
    12181 ggcatggatt ctggtattag catcaagcat attctacaaa atatgaaaaa caaaaaactt
    12241 tcacaaaatc cttgaaaaat ctcacaatca tgctataata atccatagag acaagtcact
    12301 tagtcccttt ctactagaga gtgcgtggtt gctggaaacg cataggaagt ctaaactgat
    12361 actactcttg agttttttat gaaaacataa aacggtggcc acgttagagc cgatcagagg
    12421 tgtccctctc ttttgaggta cataaatgaa ggtggaacca cgttgcgacg tcctttcgag
    12481 gatgtcgcat ttttttatta ggatactaat tatggagttg caagaattag tggagcgcag
    12541 ttgggcaatc cgacaagctt atcacgaact ggaagttaag catcatgatt tcaagtggac
    12601 ggtagaagaa gacctcttgg ctttatctaa tgatattgga aatttccaac gactggtgat
    12661 gacaaagcaa ggacgctact atgatgaaac accctacaca ctggaacaaa aactttcaga
    12721 aaatatctgg tggctattag aactttctca acgtttggat atagacattc tgacggaaat
    12781 ggaaaacttc ctctctgata aagaaaagca attgaacgtt aggacttgga agtagtctgc
    12841 tgataaaaaa tcaatgctta gaaactatga aataataaaa aaggagaaca tcatgattaa
    12901 cattactttc ccagatggcg ctgttcgtga attcgaatct ggcgtaacaa cttttgaaat
    12961 tgcccaatct atcagcaatt ccctagctaa aaaagccttg gctggtaaat tcaacggcaa
    13021 actcatcgac actactcgcg ctatcactga agatggaagc atcgaaattg tgacacctga
    13081 tcacgaagat gcccttccaa tcttgcgtca ctcagcagct cacttgttcg cccaagcagc
    13141 tcgtcgtctt ttcccagaca ttcacttggg agttggtcca gccatcgaag atggtttcta
    13201 ctacgatact gacaacacag ctggtcaaat ctctaacgaa gaccttcctc gtatcgaaga
    13261 agaaatgcaa aaaatcgtca aagaaaactt cccatctatt cgtgaagaag tgactaaaga
    13321 cgaggcacgt gaaatcttca aaaatgaccc ttacaagttg gaattgattg aagaacactc
    13381 agaagacgaa ggcggtttga ctatctatcg tcagggtgaa tatgtagacc tctgccgtgg
    13441 acctcacgtt ccatcaacag gtcgtatcca aatcttccac cttctccatg tagctggtgc
    13501 gtactggcgt ggaaacagcg acaacgctat gatgcaacgt atctacggta cagcttggtt
    13561 tgacaagaaa gacttgaaaa actaccttca aatgcgtgaa gaagctaagg aacgtgacca
    13621 ccgtaaactt ggtaaagagc ttgacctctt tatgatttca caagaagtgg gacaaggttt
    13681 gccattctgg ttgccaaatg gtgcgactat ccgtcgtgaa ttggaacgct acatcgtaaa
    13741 caaagagttg gcttctggct accaacacgt ctacactcca ccacttgctt ctgttgagct
    13801 ttacaagact tctggtcact gggatcatta ccaagaagac atgttcccaa ccatggacat
    13861 gggtgacggg gaagaatttg tccttcgtcc aatgaactgt ccgcaccaca tccaagtttt
    13921 caaacaccat gttcactctt accgtgaatt gccaatccgt atcgctgaaa tcggtatgat
    13981 gcaccgttac gaaaaatctg gtgccctcac tggccttcaa cgtgtacgtg aaatgtcact
    14041 caacgacggt cacctattcg ttactccaga acaaatccaa gaagaattcc aacgtgccct
    14101 tcagttgatt atcgatgttt atgaagactt caacttgact gactaccgct tccgcctctc
    14161 tcttcgtgac cctcaagata ctcataagta ctttgataac gatgagatgt gggaaaatgc
    14221 ccaaaccatg cttcgtgcag ctcttgatga aatgggcgtg gactactttg aagccgaagg
    14281 tgaagcagcc ttctacggac caaaattgga tatccagatt aaaactgccc ttggaaaaga
    14341 agaaaccctt tctactatcc aacttgattt cttgttgcca gaacgcttcg acctcaaata
    14401 catcggagct gatggcgaag atcaccgtcc agtcatgatc caccgtgggg ttatctcaac
    14461 tatggaacgc ttcacagcta tcttgattga gaactacaag ggggccttcc caacatggct
    14521 ggcaccacac caagtaaccc tcatcccagt atctaacgaa aaacacgtgg actacgcttg
    14581 ggaagtggcc aagaaactcc gtgaccgcgg tgtccgtgca gacgtagatg agcgcaatga
    14641 aaaaatgcag ttcaagattc gtgcttcaca aaccagcaag attccttacc aattaattgt
    14701 tggagacaaa gaaatggaag acgaaacagt caacgttcgt cgctacggcc aaaaagaaac
    14761 acaaactgtc tcagttgata attttgttca agctatccta gctgatatcg ccaacaaatc
    14821 acgcgttgag aaataagagt ctagcataaa agcctccaat ctggaggctt tttctcatct
    14881 atttttactc aaggactaag ttcacttgag caaactgaat ccgcactgtc gttccttttc
    14941 cgacctcaga ctcgatacga atctggtgcc ccagttcttc agaaattttc ttagatagat
    15001 aaaggccaag tccagaggac tgctgggtca aacggccatt gtatcctgaa aagccacgtt
    15061 caaatactcg gaggacatca ctgtttttta tcccgattcc cgtatctttg atacaaagct
    15121 cttggtcatc catataaatc tccagaccac cttccttggt gtacttgaga ctgtttgaga
    15181 tgatttgctc aataaccact agcagccact ttttatccgt cacgatttct ttatcaaggt
    15241 catgtagatt gacatttaag cctttttgaa taaagaaaag agcatattta cgaattattt
    15301 ccttgaccaa gtcctcaatt tgaacctgct ttaagaccaa atcatcatgg aaactttcta
    15361 aacgcaggta ctgtaaaact aggttggtat aggagtcgat tttgaaaatt tcctgttcta
    15421 gttgctgctt cagttggcgg tcgaccactt ctgcaactaa gagttgactg gctgcaatgg
    15481 gggtctttat ctgatggacc cacaaggtat agtaatccag caaatccgtc agttttcttt
    15541 ctgcttttga cctctgctga tagagttcca tctcacgcgc ttctaatttt tctgctaaag
    15601 ctatttccaa aggagacttg gcttccctct ctccatagag aagttcctgg cgatagacct
    15661 gcgtttccac caatatgtcc caagtgaaaa ataatatggt tacaaagcaa cacaagaaga
    15721 aaaagtagag gaagtaaatt cctagactgg caaataaaaa ctgaaagagt aagacaagaa
    15781 atgccaaaga aagcagatag ataaaaagac gactacggga gcgcagatag gctagaaaaa
    15841 attgtttcca atcaagcatg cttcaatccg taccctattc ctttcttggt ctcgataaat
    15901 cctaccaatc cctgctcctc caacttttta cgcaaacgag ccacattgac agagagggta
    15961 ttatcatcaa tgaaaaagtc actgttccaa agttcccgca tcaggtcgtc acgtgctacg
    16021 atgttgcctg catgctcaaa taacacgcgt aaaatctgga attcattctt ggtcaaattc
    16081 aagacttgcc cttgataatg taaatccatg gatttggtat tgaggataac accagcatat
    16141 tccagcaaac tctcatcacg cccaaactca taggaacgac gcaacaagcc ctgaacctta
    16201 gctaaaagaa cctgctggtc aaaaggcttg gtcacaaagt catccgcccc catattgatt
    16261 gccatgacaa tatccatagc ctggtctctc gaagaaagaa acatgatagg taccttggaa
    16321 atcttgcgga tttcctgaca ccagtgataa ccattaaaca agggcaaacc aatatccatg
    16381 aggaccagat gaggttccga ctgaacaaat agactcaaaa cttccataaa gtcttctacc
    16441 aggaccactt caaatcccca ttcagagagc attttcccaa tctgttgacg aatgacctga
    16501 tcatcttcta ttaataaaat cttgtgcatg cgcttctcct tttccattat tataacagat
    16561 ttttccatgc tagatggtct gaaactgaat ttgaaatagc ctgtttttag ccagtacaaa
    16621 caggctatgc tactagctaa tttgagggaa atttgctaag ataaataaaa agaaaggagc
    16681 tcttatggcc aatatttttg actatctgaa agatgtcgca tatgattctt attacgacct
    16741 tcccttgaat gagttagaca ttctaacctt aatagaaatc acctacctct cctttgataa
    16801 tctggtctcc acacttcctc aacgtctttt agatctagca cctcaggttc caagagagcc
    16861 caccatgctt actagcaaaa atcgccttca attattagat gaattggctc aacacaagcg
    16921 cttcaaaaat tgcaaactct cccattttat caacgacatc gaccctgaac tgcaaaagca
    16981 atttgcggct atgacttatc gtgtcagcct cgatacctat ctgattgtct ttcgtgggac
    17041 agatgacagt atcattggct ggaaggaaga tttccacctg acctatatga aggaaattcc
    17101 tgctcaaaag cacgcccttc gctatttaaa gaactttttt gcccatcatc ctaagcaaaa
    17161 ggttattctg gctgggcatt ccaagggagg aaatctcgct atctatgctg ctagccaaat
    17221 tgagcaaagt ttgcaaaatc agatcacagc agtttataca tttgatgcac ctggtctcca
    17281 tcaagaattg acacagactg cgggttatca aaggataatg gatagaagca agatattcat
    17341 tccacaaggt tccattatcg gtatgatgct ggaaattcct gctcaccaaa tcatcgttca
    17401 gagtactgcc ctgggtggca tcgcccagca cgataccttt agttggcaga ttgaggacaa
    17461 gcacttcgtt caactggata agaccaacag tgatagccgg caagtagaca caacctttaa
    17521 agaatgggtg gccacagtcc ctgacgaaga acttcagctc tacttcgacc tcttctttgg
    17581 cactattctt gatgctggta ttagctctat caatgacttg gcttccttaa aggcgcttga
    17641 atacattcat catctctttg tccaagctca atccctcact ccagaagaaa gagaaacctt
    17701 gggtcgcctt acccagttat tgattgatac tcgttaccat gcatggaaaa atagataata
    17761 ctcttgaaaa ttaaatgtat acaaaacaaa agacctagaa tacatacttt catgttcatt
    17821 ctaagtcttt ttaaatagaa tctaatagtc aataaaaatc aaagagcatt gagagataat
    17881 ggggcttgga acgtccctct cgtttcaaca aaatgacccc attatagatt aaaaagatgc
    17941 cacttagaaa aagcaaaaaa ggaagtaaga caaaggcaaa tacataaaaa gctaactgaa
    18001 cattctcgta tccattttta taaaaaaggt aggatagata aaaataactt gaaatgaggg
    18061 ataataaaaa taatactgga ttccacaaac ttctattatc cttccaaaat gacactataa
    18121 aggctaatac aatttctata acgagataca tttcttactc ctttaatagc tacattttat
    18181 cataattatc caaagaaaaa aagagggcat ttatccctct taatccttca tctgactctc
    18241 tgcatcggcc acgacttttt ctagactggt ctgaccaagt tctgcctcca tagtcaactg
    18301 aattctctcc aatttttgat ccaaaacatc atgaatatga gctcctacag ggcaatttgg
    18361 attcggattg tcatggaaac tgaagagttg acctgtctta ccaagacatt cgaccgcctg
    18421 ataaacatct aaaagactaa tatccttaag gtccttgaca atctctgttc cgcccgttcc
    18481 acgcgctact gaaatcagct ctgccttctt caactgggac aagatctttc tgataatgac
    18541 aggattgacc ccaacactag cagccagaaa atcactggtc accttgcttt ccttcccctc
    18601 gagggcaatg attatcagca tatgagttgc aatggtaaat ctacttggaa tttgcatcct
    18661 cttctccttt ttacgaggct accctgcctc tactcttctt tttctattat tatacccttt
    18721 ttagttgtaa tgtcaatcgt taccactttt caaccagtcg tctaactccc gatcgcaacc
    18781 ctctttctga gccaattctc tcaaaaattc ctgatgatga gtatggtgga tcccattgac
    18841 cagactttca tagtaaacct caaaataggg aagtctcagg tctttagcca gctgcaattc
    18901 agctgccaca tcgtaatcta cccgtcggaa gtccatatct accaggccct tgtcatcaaa
    18961 ctccaaaatc atatactggg cccgcaagtc cttccgtagc tgagcgtcca aaaagaaagg
    19021 ttggccaatc gaacccggat tgacaatcaa ttgcccacca gtcccgtaac gaagcaactg
    19081 ctggtgaatg tgtccataaa cagcaatatc acagggagga tgagtcacca agcggtcaaa
    19141 ctcctcttgt ttgccagtat gaatcaactc tcgcccccag ttcttatcag gcagatgatg
    19201 gctaattccc actgtcaaat ccccaaactg acgatgaatt tgaagaggtt gattgtggag
    19261 cacttcaatt tcttctaggg aaatttcctc taaaacatac tggcactggc gcaagagata
    19321 gcgttgacta gggcgagtac tatccaattc cttacggaca ccatgccaaa gactgtcttc
    19381 ccagtttccc aaaactctag ccgtaatcgg tagttgatcc aacaagtcca aaatccttct
    19441 acgccctgtc cctggcatga gaatatctcc caaaagccag tattcatcca ctcctagctg
    19501 ccgagcatct gccaaaacag cctccaaggc ggtggtattt ccatgaatat ctgaaagaag
    19561 agctattttc gtcatatcca tctcctcgtt ttttctcttg caataagtat aacataaaaa
    19621 gtcacagcta gagaaatcta gctttttttg atatactaga taaagatatt agacaagagg
    19681 aaacgaatga ccccaaacaa agaagactat ctaaaatgta tttatgaaat tggcatagac
    19741 ctgcataaga ttaccaacaa ggaaattgcg gctcgcatgc aagtctctcc ccctgccgta
    19801 actgaaatga tcaaacgaat gaaaagtgaa aatctcatcc taaaggacaa ggaatgtggc
    19861 tatctactga ctgacctcgg tctcaaactg gtctctgagc tctatcgtaa gcaccgcttg
    19921 attgaagttt ttctagttca tcatttagac tatacaagtg accagattca cgaggaagct
    19981 gaggtcttgg aacacactgt ctctgacctg ttcgtggaaa gactagataa actgctaggt
    20041 ttccctaaaa cctgccccca cggaggaact attcctgcca agggagaact cctcgttgaa
    20101 atcaataacc tcccactagc tgatatcaag gaagctggcg cctaccgcct gactcggatg
    20161 cacgatagtt ttgacattct ccattatctg gacaagcact cacttcacat cggtgaccag
    20221 ctccaagtta agcagtttga tggcttcagc aataccttca ctatcctcag taacgacgag
    20281 gatttacaag tgaatatgga cattgcaaaa caactctatg tcgagaaaat caactaattt
    20341 ctcaagtccc ctaccaaccc tgaaagtttt
//
LOCUS       DAYYYC010000039        20314 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.039, whole genome shotgun sequence.
ACCESSION   DAYYYC010000039 DAYYYC010000000
VERSION     DAYYYC010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20314
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.039"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(<1..517)
                     /locus_tag="ACHBV5_001486"
     CDS             complement(<1..517)
                     /locus_tag="ACHBV5_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HFM9967256.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVAVASLVMGSVVHATEKEVTT
                     QVPTYSNMAKTEHRKAAKQVVDEYIEKMLREIQLDRRKHTQNFAFNMKLSAIKTEYLY
                     GLKEKSEAELPSSEAELPSEVKAKLDAAFEQFKKDTLKLGEKVAEAEKKVAEAEKKAK
                     AQKEEDRRNYPT"
     gene            complement(596..1123)
                     /locus_tag="ACHBV5_001487"
     CDS             complement(596..1123)
                     /locus_tag="ACHBV5_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HFM9967257.1"
                     /translation="MVLAIILVIFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMSMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(1218..2549)
                     /gene="hk06"
                     /locus_tag="ACHBV5_001488"
     CDS             complement(1218..2549)
                     /gene="hk06"
                     /locus_tag="ACHBV5_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HFM9967258.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(2546..3199)
                     /gene="rr06"
                     /locus_tag="ACHBV5_001489"
     CDS             complement(2546..3199)
                     /gene="rr06"
                     /locus_tag="ACHBV5_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HFM9967259.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(3520..5952)
                     /locus_tag="ACHBV5_001490"
     CDS             complement(3520..5952)
                     /locus_tag="ACHBV5_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFM9967260.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIATLRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(5954..6412)
                     /locus_tag="ACHBV5_001491"
     CDS             complement(5954..6412)
                     /locus_tag="ACHBV5_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFM9967261.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            complement(6531..7259)
                     /locus_tag="ACHBV5_001492"
     CDS             complement(6531..7259)
                     /locus_tag="ACHBV5_001492"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9967262.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPQGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            complement(7259..8266)
                     /locus_tag="ACHBV5_001493"
     CDS             complement(7259..8266)
                     /locus_tag="ACHBV5_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM9967263.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(8304..9062)
                     /locus_tag="ACHBV5_001494"
     CDS             complement(8304..9062)
                     /locus_tag="ACHBV5_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9967264.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWFNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            complement(9025..9315)
                     /locus_tag="ACHBV5_001495"
     CDS             complement(9025..9315)
                     /locus_tag="ACHBV5_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HFM9967265.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQGADNVFSNVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(9386..9488)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(9571..10917)
                     /gene="cbpD"
                     /locus_tag="ACHBV5_001496"
     CDS             complement(9571..10917)
                     /gene="cbpD"
                     /locus_tag="ACHBV5_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HFM9967266.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     gene            complement(11006..11272)
                     /locus_tag="ACHBV5_001497"
     CDS             complement(11006..11272)
                     /locus_tag="ACHBV5_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFM9967267.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(11274..12626)
                     /gene="dnaB"
                     /locus_tag="ACHBV5_001498"
     CDS             complement(11274..12626)
                     /gene="dnaB"
                     /locus_tag="ACHBV5_001498"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFM9967268.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(12670..13122)
                     /gene="rplI"
                     /locus_tag="ACHBV5_001499"
     CDS             complement(12670..13122)
                     /gene="rplI"
                     /locus_tag="ACHBV5_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFM9967269.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(13119..15092)
                     /locus_tag="ACHBV5_001500"
     CDS             complement(13119..15092)
                     /locus_tag="ACHBV5_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFM9967270.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            complement(15228..15776)
                     /gene="raiA"
                     /locus_tag="ACHBV5_001501"
     CDS             complement(15228..15776)
                     /gene="raiA"
                     /locus_tag="ACHBV5_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFM9967271.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(15856..16518)
                     /locus_tag="ACHBV5_001502"
     CDS             complement(15856..16518)
                     /locus_tag="ACHBV5_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFM9967272.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(16515..17813)
                     /locus_tag="ACHBV5_001503"
     CDS             complement(16515..17813)
                     /locus_tag="ACHBV5_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFM9967273.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQVVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            17869..18504
                     /locus_tag="ACHBV5_001504"
     CDS             17869..18504
                     /locus_tag="ACHBV5_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFM9967274.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHGLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            18789..19709
                     /gene="cysK"
                     /locus_tag="ACHBV5_001505"
     CDS             18789..19709
                     /gene="cysK"
                     /locus_tag="ACHBV5_001505"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFM9967275.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(19948..20314)
                     /locus_tag="ACHBV5_001506"
                     /pseudo
     CDS             complement(19948..20314)
                     /locus_tag="ACHBV5_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_068988785.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
BASE COUNT         6059 a         4616 c         3353 g         6286 t
ORIGIN      
        1 tggttgggta gttacggcga tcttcttctt tttgagcctt ggcttttttc tcagcttctg
       61 caaccttctt ctcagcttct gctacctttt ctcctagttt caatgtatct tttttaaact
      121 gctcaaaagc tgcgtctaac tttgctttta cttctgacgg caactcagct tccgatgacg
      181 gcaactcagc ttccgacttc tcttttaatc catacaaata ctccgtttta attgcgctca
      241 acttcatgtt gaaggcgaaa ttttgggtat gttttcttct atctaattga atctccctca
      301 acattttttc tatatattca tcgacgactt gtttagcagc tttcctatgt tctgtctttg
      361 ccatattaga ataagtgggt acttgggtag ttacctcctt ctctgtcgca tgaaccacac
      421 ttcccataac aagactggca acagctacac tagctactcc aatactaaat ttacgaattg
      481 aataatgtac ttttctttcg ctttttgatg caaacatgtt tatttccttc tatatttttt
      541 ctttaacctt actatatcac ttcaatatga actgtatata aatcgaattt tgtatttatc
      601 tctttatgct tccatttggg attataactt catgtaatag cttttcctct tcagctattc
      661 gtcgatacaa aataactgca taaactggaa aaactaaaac aaaagtcata taggcatgac
      721 tcaacaaggt caagccaatc aactcaggaa ggatatttaa aaagtaatta ggatgtttta
      781 ctgtcctaaa taagatatga tctacatatt tgtgattatt gacaagcata agcttcactg
      841 tccaaatatc tcccaacaag tgaatcacca acatcaacat cagcatagaa aaaataagca
      901 agactaaacc aaccatgctc ataccatcaa acattgtctt atgcaccatt gcttcaacga
      961 ggcaagagag ataaaaaaca atatgagcca acgttaatcg ttttgtattc tcaactccaa
     1021 attctttccc gccattgcta aggattcgtt tctcattctc tatcgaacgc tttaaaaaaa
     1081 tcaatcgaat aaggaatatt actaaaataa tcgctaatac catattagta tcctttcttt
     1141 tatctatatt tttatctata taaagaataa tacacttatg ttaaccctat gtgaacttta
     1201 ataaaaaact aatctgtcta caagctaatc ttaaattcca taccgtgttc ataagggaga
     1261 aaactataat ccatttgata gctttctaaa atattattca caatgtaaag acccaaaccg
     1321 gaactttcat ccttatctgt cacgatttga gaatgataga atatatcaaa taaatgttct
     1381 agttcttggt cacttagagg cgcacatgta tttttgatag agagatagcc atcttgctcg
     1441 gatatgatta cacgcccatt tttatctgaa tatttaattg cattactaat caggtttgtc
     1501 aaaaccttat ccaatgccct aagactcatg acgaccctgg tagcatctgt caattgattt
     1561 tcaattgtaa cacctattga atgagctaat tcttgataac gtgataaaat atctactaaa
     1621 actggcttaa cagtcaaggt ctcacgacac tctgtccact cttggaattt agaagactcc
     1681 agtacttctt ccaataagtg gctcatctgg tcaatcttat ttatactctt tgcaatatat
     1741 tttggatgat ctttgtaatc tccaatatta tgctgcatat tctctaggat aattctaaga
     1801 ctggctaaag gggttttcaa ctcatgtgat gctccgcgga caaaggaaac cttttgattt
     1861 tgcaatttta caatttgctc attacgactt tccaactcat gaataacctt caacaagtgc
     1921 tcatacatac cattaatctg ttttccaact tcaccaactt catctttcct actttcatca
     1981 aaacgaatat tgtcatccaa atcttgcatt ttactagtca cttctgaaat gtaaaaaaga
     2041 ggattgagca agcgtttagt ataaaaataa gaaaaaacaa aggaaaaagc aattgtaacc
     2101 aaaaatgtat atgggagata caaaagcaaa atattctttg cttctttgta gacatccacc
     2161 ccgtgaacaa attgcacggt tacctgttta ccatctgctg tactaacaga catatctaac
     2221 atcacgatat aatttgatag ctttccatct ttaatatcca agtcatgcac aagagggagc
     2281 cgcttatcta caatatctct tttaaggtga gcagatatgg tcaaggactt tgaataagac
     2341 tggagtaagc ttggaatttc atcagatgtc ttagtcttta aatactccgt aaacactctt
     2401 gcgctctcat taaacttttc cccctccagt tgaatataat aaaaaggaaa ggtcaaataa
     2461 atagctatat gaatgactag accaacacca cctagaattg caaaacttct taaaaaagac
     2521 ttggttaata atttaggatt ttttatcata agctaatctt atacccaaca tttttcacag
     2581 tcacgataca atctaaagct aattttttgc gaagagtacg aatatagaca tcaacgaccc
     2641 tatcacaagg taaatcagct acatcttttg aaatttcttc caatatctgc tctctactta
     2701 aaacttgatt tttatgctga atcaaacact ttagtaccag taattccttt ggtttgagat
     2761 caatttcttc atttttataa tgtgctttgt aagaggtaaa atccactgtt acatcctgat
     2821 atcgccaaag atcctctatg acgtagtaac gtctgataag cgccttaata cgcttgacaa
     2881 gcagtaccaa agaaaaaggt tttgtcacat gatcatcagc atagagatca aatacctgtg
     2941 actgagtagt ttcatctccc agagcactca agacgatgac aggaatatcg tgcttttgat
     3001 tgatttcttt taacacttca aaaccactct tcctaggcat cattaaatcc agtaccatga
     3061 gatggatagg gagatcttga aatttttcca agacctcttg tccatcctta gccataatga
     3121 catgataacc ctcttctgtc agaaatgctg caattccttc tctaatcatt tcctcgtcat
     3181 ctgcaactaa aatgttcatc tctctccctt tctactacca gaactccata catctatttc
     3241 ctgtatgcta tttgaaaatt tcctaccagc ctatcatcta tgataatgga atggatttca
     3301 tttatccgct actttttgtc aacaacaacg tcaatacaag aaaatcattc atcttgcagc
     3361 ttatactctt cgaaaatctc ttcaaaccac gtcagctcta tctgcaacct caaaccagtg
     3421 ttttgagcaa cctgcggcta gctgcctagt ttgctctttg attttcattg agtttcactc
     3481 cactgtgact tatggtcaga tgctggtact tttattcttt tatgcaatat caaattttaa
     3541 ctggcctgct ttgacaccaa tcttaagtgt gctgcctgcc actaaatctc ccttgagaag
     3601 aagttctgcc aacttgtcct ccacttctgt ttgcagggtt ctgcgaagtg ggcgagctcc
     3661 catctctggg tcatatcctt gatttgctaa caatttcaga gctgaagctt gtaatttcaa
     3721 gtcaatgcct ttttcagcca aacttgccac taaaggcttg accataatct tcaccacttc
     3781 ctgcatatgg tcactagata ggctatggaa gaccaccttc tcatcaatac ggttgatgaa
     3841 ttccggtcta taagcttttt tcagttcttc aaacatgcgt ttttccatat tttcctggtc
     3901 aaaacgaata tccttagccc caaaaccaac agtcttatca tcacgaaggg cagtcgcacc
     3961 taggttcgat gtcataatga taatggtatt tgaaaaatcg accttgcgtc ccttgctatc
     4021 tgtcaagaca ccgtcatcca gaacctgcaa gagaacatta aagatatctg ggtgagcctt
     4081 ctctacctca tcaaagagga gaacggaata gggtttattg cgaaccttct ctgtcaactc
     4141 cccaccttct tcgtaaccca catagcctgg aggagctcca tttagacggc tggctgcgaa
     4201 tttctccata tactcactca tatcaaagcg gataagggct gattcgtcat caaagagaac
     4261 ttctgccaaa gccttggcca actcggtctt accgacacct gtgggtccta ggaacataaa
     4321 ggaaccgatc ggacgcttgt gactgcgaat tcctgactga ttacggcgaa tcgcacgact
     4381 aatacttgaa acagcttgat cttgaccgat aacccgttta tggagttctg cttcaagatt
     4441 tagatatttc ttagcgtcag tctgagtcag tttttgaact gggattcctg acaagcgact
     4501 caaggtggtc aaaatatcag actctgtcac caagtctttg tagacaggta cttcctcttc
     4561 ttttgcgatt agctgggctg cctgtttcca cttgccatcc atcagggcct tgtcagctgg
     4621 actcaaatct gaatcgtctg cttttacata ctttgcctta ttttgcactg ttgctgctgc
     4681 ttcgtccaag aggtcgatag cagagtctgg caagtgacga ctggttaaat aacgatgagc
     4741 catcttaacc gctgtttcaa ccgcttcatc tgtgatttgt acacggtgat gtttctcata
     4801 agtcgccttc aaaccttgta aaatagtcat actatctgcc acacttggtt cttcaatcgt
     4861 cactttagcg aaacgacgag aaagagccgc atctttttcg atatgttttt gatattcttc
     4921 ctgagtggtg gcaccaaccg ttctcaaagt tccacgcgcc aaggctggtt tcaagatatt
     4981 ggccgcatcc agagtcgaat caatcccgct accagaaccc atgatggtgt ggagttcatc
     5041 gataaagagg atgacttggc catcttcttc aatatccttg atgatattat tcatgcgttc
     5101 ttcaaagtca ccacggaagc gtgtccctgc aacgacattc atcaaatcaa gttctaacac
     5161 gcgcatctta gccatttccg caggcacgtc accactagca atacgctgag caagaccaag
     5221 ggccagagct gttttcccga caccagcatc cccaaccaag acagggttgt tcttagtctt
     5281 acggctcaat atttgaatca tacgtgagat ttccttgtcc cgaccgatga ctggttctaa
     5341 cttgccagaa cgcgcttgct ctgtcaaatc atgcgtatag tcctcgagac caccactagg
     5401 agtctgcggc atgcccatca tattggccat agaattttgc ttgtcagcta ctgtacgatg
     5461 gcgttggcgt aaagccttga gatcttcacg agtccagcct gcacgttctt ctaaatttcg
     5521 acgaagggta gcaatcttga cctgatcttt cttgtcttca taagaaaaac cagccctctc
     5581 caagatacga gttgccaagg cattgccatc atgcaaaatc gcatagaaga cgtgctctgt
     5641 ccctagcacc ttagcatgga ccactgacgc tacatactct gcttcgtcaa aaagaacctg
     5701 caaacgacgg gagaacggca attccgtaaa ggtttcatcc tggctatagt ccgtttcagt
     5761 cagttccaaa gccacctctt ctaaacggtc catctcatac ggataatcat ttaaagttgc
     5821 ccctgctaca ctataactgt gattagacat ggcaatcaac aagtgccacg actctagata
     5881 acgagctcca aaatgtccag caaccatgta ggcactttcg atacattcat tcaatgcttt
     5941 tgaatagttc atcttacttc ccttttctat ctacctcttg tatgatctga cgtagcatgt
     6001 ttgctcgaac aactggagct tcttctccta aaacgcgatc caaagctact gattctagca
     6061 aattcatctc ctgcttggtc atcaattcct gctcaaccaa aagctggaga atatcctcat
     6121 aaatttcttg actgactcgc tcaccaatcg agtaaagcag ctcccggagc atttcatgat
     6181 gactagaaaa ctcaatccgt cctatacgaa tgtagcctcc gccaccacgc ttactttcaa
     6241 ccaagtagcc tctactttcc gtaaagcgtg tcttgatcac gtagttaatc tgactaggaa
     6301 caacctgaaa ggtatctgcc aactgactcc gttgcaactc cacgatacca gattgatcta
     6361 aaatcgcctt gatgtaggcc tcaatatgat ccgatgtatt tttaaatctc ataacaaacc
     6421 cacctctctc tttaaacctt gaccttgttt gactattata ccgaaatttt ctcattttta
     6481 aaagaaaaag ggcgctggta aaggataatc ttcaccaact ccctattttt ctacttatct
     6541 aagcctaatt ctgccaagat ttgacgtttg taggcaatct tttgaacttc cttgtcctca
     6601 tcttcagacc aatctagttt aatttctgaa acaatctgcc cagggcgatt tttcaagata
     6661 tagatgcggt cactgagatt gagggcctcc tcgatactgt gagtaataat caaggttgtt
     6721 agctgcaact gcttgtgaat ctcaaggtac caagcgtgga gttccatctt tgtcatctca
     6781 tccaaggcgc taaaggcctc atctaagaga aagagcttgt gcccaaaaag gtaggtccgg
     6841 agtaaggcta cacgctggcg catcccaccg ctaagttcat gaggatactt gtctcttaca
     6901 gctgtcagct ggaaggtcgc aagaatttta tccgctcggg aaatagcttc tgccttatcc
     6961 accttttgaa tcaagagggg cagaatgata tttccaagca ccgtcttgtg ctccaagagc
     7021 agatcctttt gcaacatata actcacgcgc ccctggggat tttcttcacc atcaaggaca
     7081 attctccctg actgaacttc taaaatccca gcgattagat taaagagggt ggtctttcca
     7141 acaccacttg ggcctaggat ggaaaccact tcgcctgaag tcacctgtag gttgatatcc
     7201 tctaaaatcc tctcctgacc ataggcataa ctgacgtgct ctagtctaat ttctgtcatt
     7261 atttcacaaa ttcattggtg aagcctttgt ctgtcaagtc ttctttaagg ataccatttt
     7321 ctttatccca tttgtagaaa gcattccagc gagctgcgtc aaattgaccc catttttcct
     7381 tgtcgcttgc gtattctttt gacaagtatt tttgagattc gatgacaaag tcacgttttt
     7441 ccttgagttc aggtgcattc ttgatgagaa tatctgcagc ttcttctgga tgttccatag
     7501 catattggta gccttttttg atggcttgga tgactttgcg agcttcttct ttgttatctt
     7561 tcagatagtc gttgtttgcg atgataactg gtgaatagta gtcaaactcc ttgacatagt
     7621 ctttcaagta catgaagtta gcatctacac cttgagattt agcaaggata ccatcccaac
     7681 cgtagtaaat ccaagcagta tcaaagacgc cattggcaat cggtgtgatt gagtttgagt
     7741 cgttatttgg tactttttca accttctcaa agtctccacc ttgagattct accaaggttt
     7801 tcaacatagc aagttcagtt gggtcattcc atgtcccata tttcttacca accaagtctt
     7861 ttggactgct tacattatca gatttacgag agatgattcc tgatgtattg tgttcaacaa
     7921 tagctgcaac ggcagtgatt cctgctcctt tttccaattt cttagccatg tagtcttgga
     7981 aatacactgc aaatggtgcc tttccgttga taaccaagtc agaagaactt tcttctggtg
     8041 gcaatttcaa atcaacatcc actccagctt ctttgaaata acctttttcc ttggcaacat
     8101 aaagccctgt gtggttggta tttggtgtcc agtctaggat aaagtcaacc ttcttaagtt
     8161 ctgcctcttt gttgtcttta gaagcagttc cttgaccaca ggccacaagc acaacagcta
     8221 caagagctgt tacaagcgtt aaaaacactt tccatgtttt cttcattttg atttcctctt
     8281 ttctttttca aaaacgctct attttaagta cgtttccatt taatcacata tttttcactg
     8341 atatcgacca gcttcatacc caaaagactg ataatcgaca ccagaataat aatggcaaac
     8401 atggtatcat actgaaacaa tttcttggac tgaatcatat aaacaccaag cccctcaaaa
     8461 cctcccaacc actcagatac cacagttgtg ataaaggcgt aggagacact gaccctcaga
     8521 cctgcataaa agtaaggcag gctaaccggg attttaaaat gccacaggat ttgccaaggg
     8581 tttgctcgca tcagactaaa caaggtcagc atatccttgt cacaatgcct aaaaccgtcc
     8641 aaaatactaa cgatgatggg aaaggttgtt gttaagataa tcaagacaat cttgggcaaa
     8701 atcccataac ctagccacaa gaccaggata ggagctatgg caatggtcgg aatggtctga
     8761 atgaccacca tcatagggta aatcaggtca ttgaaccaag tcaaactatc catgagtaca
     8821 gccataagac aggcaatcaa aactcccaaa atcagcccca gtaaagccac tctcaaggtc
     8881 gcccagctat ggtgccagag aaattctctg tcacgaacaa agggctggag aatttcaaga
     8941 ggtgtcggca ggataaactt ggggagaagt ttaagaaaac ctgctaactg ccagattgac
     9001 aagactccga gaaagcccaa tagactaatg tgtcgtctca gtatacttct caagtttctc
     9061 atcaatactt aaaatctctc ctacatttat tttgacattg gaaaagacat tgtctgcccc
     9121 ctgccctgcc acttccagcg cttcttttag aatgcgcata agctcatcaa actccccttc
     9181 caagaccgtt tcaaatggtg tcactaccat cgtcacttct tgagtttgca gataagcaat
     9241 gacctgatca ataacagcta tccgatcaat cccctgtgct aggggtaaaa cttgcaaggc
     9301 aatgcttgct ttcataagaa cctcctcttc tcgttttcct ttttaaaaaa agaaaaacct
     9361 ttaccataca tggaaaaggt gcaaaattag actaagtatc gttccctccg ctggcattac
     9421 ccagatcagg tgcggtcgaa gtttaacact tcctctcaga ctgtacacag actcccatat
     9481 attatatgta tatatgatag cgcaaaataa gaaaaatgtc aaggaaactg cttacagaaa
     9541 agagcaggaa atttctccta ctccaatttt ctatactcgt tctccatcac tgtttactct
     9601 gtagccatcc accgtcgtat taacagctaa ggcgcctgaa gagtaagaat aataccactt
     9661 accagagacc tggtaccagc ctgttttcat tgcccctgaa ctacccagat aataccacga
     9721 gccattctcc tttaaccatc ctgtctgcat ttcaccagat aatttcaaat aataccagct
     9781 agaaccatct ttcagccatc ctgttgattt agaaccattt gatttgaaat gataccaact
     9841 accatttatt ttcttccaac cgacagttga actattattg gatccatagc tagagatatt
     9901 tcctgattga ttctgataat tttgtgaaga agtcactccc tctagctgta tatagcgacg
     9961 acttccgtta taagccgtat aactcaacca cttgtagccg tctttttcaa gtatctgatc
    10021 ataatgaacc ttctccccag gataatagta atcaatcaca gttgcactaa ctaggggttc
    10081 agttttgata gcagacttgg tcttaaaata atgagttcca cctgttgaag aaagaacaga
    10141 attacctaga ggatttttat tcacagcctc caattgaaca taacgatagc ttccattata
    10201 ggcagtataa ctcaaccact tgtagccgtc tttttcgaga atttgatcat aatgaacctt
    10261 ctctccagga taatagtaat caatcacagt tgcactaact aggggttcag ttttaatagc
    10321 agacttggtc ttaaaataat gagttccgcc tgttgaagtt gaggattgac tattcccaac
    10381 actgccacca tccaaatctt taaaatgaat aaatcctgtc atcgtgtttg cttttataat
    10441 tcgtttatta taggattctg tataaccata gttatattcc tcaatctcaa tctgatctcc
    10501 cattacattt gacacccagg caacatgacc ataagttcct gcagtagacc aagtaatgga
    10561 accaatcgtc ggtgtattat ctacacgata accttcccga cgagcacgat gtccccattc
    10621 attcgcattt ccataagctg ccggaatttc aaaaccattg acattactca aacgaaaggc
    10681 tacaaaagaa gtacactgac gagaatacat gcgccactga tcaatctcct ggctcccatt
    10741 tttataataa gcaggataat catccccacg cgcaatcgat ccatttcctc tggaataggc
    10801 atagacacta tcaccagctg ctagcatcaa tcctactact aaaaaaggaa caagcttttt
    10861 aactgacatc ttcaagtaat aacttgttcc tcttgctata aacggtaaaa ttttcattct
    10921 tcctccttaa aaaataatat aaagcgatga ttgccttcac ctaaattatt cggagaaaaa
    10981 agaaaaagtg agaaaatttc tcactttagt caagataatg aatcaaattc ttttctgtaa
    11041 gaatatctga gtaagtaaag gattcaacgt aaacattaac ttgtttatct ccttccacat
    11101 ccccaaactc cacaataaat agggatggat aaacttcaat tagcttaccc aatctatttt
    11161 tttggcgctt acgaccattc tccaaagtca tttctacgac ttgtccctca tgtgccttga
    11221 tttcttcttt gatttttttc atcttggcta catctgtaaa tgcatctgac atcttatgcc
    11281 tccctctttg agatacttga aaatttattg tattcttttt ggaaaatcaa ttccactgtt
    11341 ccacgagctc cactacggtt tttctcgata ataacttcca ccttattatt tgggataccc
    11401 tcctcttctt caccaccacg ttcatagtag tcatcgcgat agagaaaagc tacgatatca
    11461 gcgtcctgct caatagaccc agattcacga atatcagaca agaccggtct cttgtcctga
    11521 cgttgttcta caccacgaga aagctgactc agagcgatta ctggaacctt caattccttg
    11581 gctagtattt tcaactgacg agaaatttca gaaacttctt gttgacgatt ttctcgacca
    11641 gttcccgtga taagttgcaa atagtctatc aaaatcaaac caagatttcc agtttcttga
    11701 gccaatttac gagaacgaga acgaatctct gtaatccgaa tacctggcgt atcatcgata
    11761 tagatactgg cgttagctag attaccctga gcaatagtat atttttgcca ctcctcatct
    11821 gtcaattgcc ctgtacggat agaatgtgac tccaccaagc cttctgcagc taacatacgg
    11881 tctaccaagc tttccgcacc catttcgagt gaaaaaatag caaccgtttt gtccaactta
    11941 gtcccaatat tctgagcgat attcaaggca aatgctgtct taccaactgc tggacgagct
    12001 gctaagataa tcaactcctc ctcatgaagt cctgttgtca tatgatccaa atcacgataa
    12061 cctgtcgcaa tacctgtaat atcggtcgtt tgttgcgagc gagcttccag atttccaaag
    12121 ttgagattca acacatctcg aatgttctta aacccgcttc gatttgcatt ttcactgaca
    12181 tcaatcaacc ctttttctgc ctgagcaata atttcatcag ctggttgtga cgcttcgtaa
    12241 gcttggttga cagactctgt caacttggca attaaacgac gtagcattgc tttttctgca
    12301 acaatcttag cataatactc cgcattagca gaagttggca cagaattaac aatctcaacc
    12361 aagtaagaca agccaccaat attctgtaaa tcaccttgat tatcaaggat agtacgaacc
    12421 gttgttgcat ctatggcatc accacgatcg gataaatcga ccatggcttg gaaaatcaaa
    12481 cgatgggcat acttaaaaaa gtcccgagac tcaatgtatt ctcgcacaaa aacaagttta
    12541 ctctcatcaa taaagatagc ccctaaaacg gattgctcag ctaagatatc ttgaggttgt
    12601 actcgtaact cttctacttc tgccatcaga cttcccttcc ttttacaatc ttgtcaagaa
    12661 ggtgtaaact tatccttctt tcacacgaag attgattaca cttgtgatat cttgatagat
    12721 tttcactggc acatcaatca aaccaaccgc tcgaatcgga gcttgtactt gaatatgacg
    12781 tttatcaatc ttaattccaa attgcttttg caattcttct gcaatcttct tattggtaat
    12841 agaaccaaag gtacgaccat ctggaccaac tttttcaaca aattctacaa cagtttcttc
    12901 tgcttcaagt tgtgctttaa ttgcttttcc ttctgcaatc atctcagcgt gagctttttc
    12961 ttccgatttt tgtttaccac gaagttcacc tacagcttga gcagtcgctt ctttggctag
    13021 attctttttg ataagaaagt tttgcgcata ccctgttggt acttccttaa tttcgccttt
    13081 tttacctttt cctttaacat ctgctaaaaa gattactttc attcttcttt ctccttttcc
    13141 tttatttcat ttaatacaat ttctgtcagt ttttcacctg cttctgacaa ggttacatct
    13201 ttaatttgag ctgctgccaa attaaagtgg cctccaccgc ctaactcttc cataatccgt
    13261 tgtacattca gtttactacg acttcgagct gagatagaga taaatccttg tgtattcttc
    13321 gcaagaacaa aactcgcttc aatacctgac atggctaaca tggcatctgc tgccttacta
    13381 ataacaactg tatcatagca tttcgtgtcc ttagcctctg ctattagtac atctgaacct
    13441 aatttacgcc cctgtaaaat aagttcattg acctcacgat attcttcaaa atctgtcgca
    13501 gcgatttcct ggatagcaat actatcactt ccgcgcgttc tgagatagct agcaacatca
    13561 aatgtccgac tagttactcg cgaggtgaaa tttttagtat ccaacatcat accagccatc
    13621 aagacacttg cttgcatacg actcaaacga tttttcttag aattctggaa ctgaatcaat
    13681 tccgttacca actcactggc actacttgca ccactttcga tataagtaat aaccgcatta
    13741 tctggaaaat cctgatccct tctatggtgg tcaataacaa tggtttgggt aaataaatca
    13801 taaaattctt ttgataatgt taaggctgtc tttgaatggt ctacaagaat caacaaagaa
    13861 cgattggtca ccatccccat tgcatcctta acagacaaca acttcgtaac tccttctttt
    13921 tctatgaatg aaacagctcg ttcaatatct ggagacattt gttcttcatc ataaagagca
    13981 tagctatttt caatcacatt gctggcgaac aactgcatac ctacagcaga gcccaaagca
    14041 tccatgtcta aatttttgtg accgactaca aaaacctgat ctacactccg aatcttatct
    14101 gaaatagctg tcatcatagc gcgcgtacga gtccgtgtac gcttgattga agcagcagac
    14161 ccaccaccaa aataaactgg atttttcgtt tcgtcgtttt ccttaacaac cacctggtcg
    14221 ccaccacgta cttcagccaa gttcaaattg agcaaagcaa ctttccctat ctcatcatga
    14281 tttccatcgc cataagaaaa tcccatactt aaggtcaagg gcaactgtct ctgtttcgac
    14341 tcttctctga aagcatcaat aacagaaaat ttatcattca tcaagccctc aagcaccgtg
    14401 tagtcagtaa atagataaaa tcgatccata cttacccgac gagaaaacat catgtatttt
    14461 tctgaaaact ctgatataaa attagctaca aaactattga tttgactaat atctgactca
    14521 gaagttgcat cctccaaatc atcataatta tccacagaga caatcccaat cactggtcga
    14581 cttgttacca attcatctgt tatggcttgt tccctggata catctacaaa atacaaaaca
    14641 ccggaagaag catccatatg aacagcataa cgcttctcac caagcttggc ataagtagac
    14701 ggatttccta ctgaagcctt gataatcgtt tgaacagctt ctaaatcaaa atcaccatct
    14761 tccttggtca aaatcaattc agcataggga ttaaaccact caacctctcc agaagataaa
    14821 ttcaatttca taacacctac aggcatttgt tccaatagag atgtcaaact ttcttccgct
    14881 tggtggttta catactgtat ctgttctaca tcactccttg tataatgcac tctcagtttc
    14941 ttaaataaaa aaacatagcc tcctacaaaa agaaacaaaa ttaaaaccgt caacagatta
    15001 ttattaacaa aaataatgaa agtggataag actccaaacg caatcaatcc tactagaata
    15061 ggaaaaattg gacttacata aaattttttc attcaaaacc tcttggcacc cattatacca
    15121 taatacccct caaaaagcga ctttttaaaa gtgtaatcag taattctatc aattataaga
    15181 aaaaggtagt ttacaattca gtaaacctac ctttacacat attgaaatta agattcttta
    15241 acctctaaca aaccaatttc gccatcctca cgacgataaa tcacattggt tgtctgatct
    15301 tcaacatcca catagataaa gaaatcatgc cccaataaat ccatttgtag aattgcttct
    15361 tccaaatcca ttggttttaa atcaatttgt tttgaacgaa caactttaga ctggacaaca
    15421 tttgaatctt ccaccaaagc atctgtaaat aattgaccag ttgctacctt atttttattt
    15481 ttacgctcga tttttgtttt atttttacga atctgacgtt caattttatc agttacaagg
    15541 tcaattgaac catacatatc ttgagataca tcttctgcgc ggagagtaat agatccaagc
    15601 ggaatcgtta cttccacttt agccgttttt tcacgataaa cttttaagtt aattcgggca
    15661 tccaactctt gttctggttg gaagtacttt tcgatctttt cgagtttaga aactacataa
    15721 tcacgaattg cttctgttac ttctaggttt tcaccacgga tactatattt aatcatatga
    15781 gtaccttctt tctaaacatt tttgttttta tgattttatt ataacgcttt cattctattt
    15841 ttgcaaattt tttcctcatc ttacaaggga aaatgttttt acatccttag caccagcttc
    15901 ttccaacagt ttcttaacac gatttatagt tgctcctgta gtatagatat catctataag
    15961 taggattttt ttaggaatag tgactccact tttaataaag aaaggaagtt ctgtccccaa
    16021 gcgctctgaa cgatttttag aagaactggc tctctcttct cttttctcta ataaatccag
    16081 atactcaaag cctgctgcct ctaccaagcc ctcaacctga ttaaatcctc tattagcata
    16141 tctatcagga cttaggggaa ttacaacaaa ttgatactct ttgtactttt tcaactcctc
    16201 acttaaaaat gaagcgaaaa cttttcttaa caggaagtct ccatcaaact tatagcgact
    16261 gaaaaaatcc ttcatagctt gattgtaagt aaaaatcgct ctatgactga cttcaactcc
    16321 ttctttacac caaagttgac aatcttgaca ctttgttgac aactctgttt tcatacaatt
    16381 tggacagttc tcttccccaa ttctttcaaa agtagaatca cagtctgaac aaagacaaga
    16441 gtcatcattc ctcagaagta agagactact aaaagttaaa acagtcttca tagtctgccc
    16501 acataacaag cacttcatag accagcctcc ttattcatca tctgaatttc cttaatcgcc
    16561 ttcttgattg aagcatttaa cccatcatgg aagaaaagca aatctcctgt cggtctatcc
    16621 atgcttcgtc caactcgtcc accaatctga atcaaactag acttggtaaa caaacgatga
    16681 ttggcctcta ctacgaaaac atccacacaa gggaaggtaa ctccgcgctc caagattgtc
    16741 gtactgataa gtattgtcag ttctccatct cgaaaagctt gtacttgctc taatcgatcc
    16801 tctgttacag aagatacaaa gccaattttc tcatttggaa attgctcctg taagatttct
    16861 gctaactgct cccctttctt aatttctgaa gcaaaaatga gtaacggata agctgtcttt
    16921 ctctgcttct caatatagga ctttaacttt ggtgacaaac gattcttgtc taagtagcga
    16981 ttaaaatccg ataaccaaat tggttttgga ataatcaacg gatttccatg aaaccgtctc
    17041 ggtaaattca gtctttttag ttctcctaaa cggacctttt tatctaactc attggtcgaa
    17101 gtcgctgtta aaaagattct caatccattc tcctttacac tattcttgac agcgtggtaa
    17161 agcatgggat tatcaacata aggaaaagca tctacttcat ccactatcag caaatcaaaa
    17221 gcttgataaa acttcaataa ctgatgggtt gttgcaacaa ctagtggtgt tcgaaaataa
    17281 ggttccgatt ctccatgtag caaagctatc ccgcaagaaa aatcctgttg caggcgcttg
    17341 tacagctcca aacaaacatc tatgcgagga ctagccaaac acactgcacc acccgcattg
    17401 atcactttag ccactacttg ataaatcatt tctgtctttc cagctcctgt taccgcatga
    17461 actaaggttg gcttttgctt gtctactact tgaagcaatc cctctgacac cttctcttga
    17521 aaaggagtta attggccgcg ccatttgaga acatcttgct ttggaaaatc ctcctgcgga
    17581 aaatagtata aagtttgatc acttctgact cgcttcatca gcaagcactc tcgacaatag
    17641 taagcaccga tgggcaaata ccattcttct agaatagtac tattacagcg ttgacagaaa
    17701 agtttcccct tctcctttct cattgctgga agtttctccg ccaactgacg ttcttcttct
    17761 gttaattcat tctcagtaaa taaacgaccg agataatcta aatttacttt catacttctt
    17821 tattcgtaaa aactagcact ttagatgatt ttttagtaca attaaatcat ggaatttagg
    17881 acaattaaag aggacggtca agtccaagaa gaaatcaaaa aatctcgctt tatctgccat
    17941 gccaagcgtg tttatagcga agaagaggct cgtgacttca ttactgccat caaaaaagaa
    18001 cactacaaag cgacacataa ctgctctgcc ttcattattg gagaacgtag tgaaattaaa
    18061 cgtacaagtg atgatggtga gcctagtggt actgctggtg ttcccatgct tggggtacta
    18121 gaaaatcaca atctcaccaa tgtctgtgtg gtcgtgacac gctactttgg tggtattaaa
    18181 ctaggcgctg gaggactaat tcgtgcttac gccggcagtg tcgccttagc tgtcaaagaa
    18241 attggtatta ttgaaataaa agaacaggct ggcattgcta ttcaaatgtc ttatgctcag
    18301 taccaagagt acagtaactt ccttaaagaa catggtctca tggagctgga tacaaacttt
    18361 acagatcaag tcgatacgat gatttatgtt gataaagaag aaaaagaaac tattaaagct
    18421 gcacttgtgg agttttttaa tggaaaagtc actttaactg accaaggttt acgagaggtt
    18481 gaagttcctg taaacttagt gtaaacaatg aataatacag cgtttcgttg acattctcac
    18541 aactacttta gcgagcaaaa taaaaagatg cgtaccaaaa tatactagaa aatgaagcaa
    18601 ttcaaacgaa acctgatatc gttttccttc acacctattt actagaatta gctgaacgca
    18661 atcacttgaa aattaatgac tttgatctat gatatataga aatcctatcg cttcgatagg
    18721 atttctatat tttacaaatg gtatggatag cgttatacta aagatatctt atacaaagag
    18781 gtattcatat gtctatttat aacaacatta ctgaattaat cggtcaaaca ccgattgtta
    18841 aacttaacaa catcgtgcca gaaggtgctg cagacgtcta tataaagctt gaagcattta
    18901 atcctggttc atctgtaaaa gaccgtattg cccttagcat gattgaaaaa gctgaacaag
    18961 atggtattct gaaacctggt tctactattg ttgaagcaac aagtggaaac accggtattg
    19021 gactttcatg ggtaggtgct gctaaagggt ataaagtcgt catcgttatg cctgaaacta
    19081 tgagtgtaga acgacgtaaa attatccaag cttatggtgc tgaactcgtc ctaactcctg
    19141 gtagcgaggg aatgaaaggt gctattgcta aggctcaaga aatcgctgct gaacgtgatg
    19201 gtttccttcc tcttcaattt gacaatccag ctaatccaga agtacacgaa agaacaacag
    19261 gagctgagat actagctgct ttcggtaaag atggattaga tgcctttgtt gctggagtag
    19321 gtactggtgg aacgatttct ggtgtttctc atgcactcaa atcagaaaat tctaacattc
    19381 aagtttttgc agtagaagca gatgaatctg ctattctatc tggtgaaaaa cctggtcctc
    19441 acaaaattca aggtatctca gctggattta ttcctgatac acttgatact aaagcctatg
    19501 atggtatcgt tcgtgtaaca tcagatgacg ctcttgcact cggacgtgaa attggtggaa
    19561 aagaaggctt ccttgtaggg atttcctcag ctgcagctat ctacggagcc atcgaggttg
    19621 ccaaaaaatt aggtacaggt aaaaaagtcc ttgccctagc accagataac ggtgaacgtt
    19681 atctctctac agcactttat gaattgtaac cgtccaataa cgaagtctat tgaaaaatct
    19741 ccagactaga gaactcacgg atagttccta atctggagat ttcttatttg cacttttctt
    19801 gtacaacttt agtccatggt aaataggcct ctaaaacctc tttgtttacg agagtttcca
    19861 cgtttggaag acattctaga agataggata gatatttctc actatttata atggattgaa
    19921 ataagatatg aacaaatcga ttagaacatg atggtaaagc gtaatccctt gtttctcagc
    19981 tttcccagac aaaaaagtcc aatagtaagt cagctgacta tcactctcta gcaccctata
    20041 agaagtttca tccgcatgaa gtaagggctg agtcaatagt ctctctcgca agaggttata
    20101 aaggggctcc aaatagtatt gactcgtctt gatatgccaa ttagagattt ccttacgtgt
    20161 gattggtaaa cccatcctag cccaatcttc ttcttggcga taattgggta ccttcagatt
    20221 aaacttctga tggatggtgt gagcgataat agaagctgag ccaaagttat gcgctaaagg
    20281 ggctttagga ataggagctt tcacaagctt atcc
//
LOCUS       DAYYYC010000040        20151 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.040, whole genome shotgun sequence.
ACCESSION   DAYYYC010000040 DAYYYC010000000
VERSION     DAYYYC010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20151
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.040"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            68..310
                     /gene="relB"
                     /locus_tag="ACHBV5_001507"
     CDS             68..310
                     /gene="relB"
                     /locus_tag="ACHBV5_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFM9967276.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            312..566
                     /locus_tag="ACHBV5_001508"
     CDS             312..566
                     /locus_tag="ACHBV5_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFM9967277.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHWRDIY"
     gene            613..1265
                     /locus_tag="ACHBV5_001509"
                     /pseudo
     CDS             613..1265
                     /locus_tag="ACHBV5_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005267 - potassium channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
     gene            complement(1525..2511)
                     /locus_tag="ACHBV5_001510"
     CDS             complement(1525..2511)
                     /locus_tag="ACHBV5_001510"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFM9967278.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            2705..5173
                     /gene="gyrA"
                     /locus_tag="ACHBV5_001511"
     CDS             2705..5173
                     /gene="gyrA"
                     /locus_tag="ACHBV5_001511"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFM9967279.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            5173..5916
                     /gene="srtA"
                     /locus_tag="ACHBV5_001512"
     CDS             5173..5916
                     /gene="srtA"
                     /locus_tag="ACHBV5_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HFM9967280.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            6160..6957
                     /locus_tag="ACHBV5_001513"
     CDS             6160..6957
                     /locus_tag="ACHBV5_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFM9967281.1"
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSIFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGSLIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            7105..8364
                     /locus_tag="ACHBV5_001514"
                     /pseudo
     CDS             7105..8364
                     /locus_tag="ACHBV5_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            8460..9734
                     /locus_tag="ACHBV5_001515"
     CDS             8460..9734
                     /locus_tag="ACHBV5_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HFM9967282.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            9744..10622
                     /gene="truB"
                     /locus_tag="ACHBV5_001516"
     CDS             9744..10622
                     /gene="truB"
                     /locus_tag="ACHBV5_001516"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFM9967283.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTKTEDASGEVVAETPVLSLLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            10863..11165
                     /locus_tag="ACHBV5_001517"
     CDS             10863..11165
                     /locus_tag="ACHBV5_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFM9967284.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            11273..11911
                     /gene="udk"
                     /locus_tag="ACHBV5_001518"
     CDS             11273..11911
                     /gene="udk"
                     /locus_tag="ACHBV5_001518"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFM9967285.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            12039..13379
                     /gene="xseA"
                     /locus_tag="ACHBV5_001519"
     CDS             12039..13379
                     /gene="xseA"
                     /locus_tag="ACHBV5_001519"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFM9967286.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            13357..13569
                     /locus_tag="ACHBV5_001520"
     CDS             13357..13569
                     /locus_tag="ACHBV5_001520"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFM9967287.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            13566..14441
                     /locus_tag="ACHBV5_001521"
     CDS             13566..14441
                     /locus_tag="ACHBV5_001521"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFM9967288.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            14434..15249
                     /locus_tag="ACHBV5_001522"
     CDS             14434..15249
                     /locus_tag="ACHBV5_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFM9967289.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDVKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            15242..15673
                     /locus_tag="ACHBV5_001523"
     CDS             15242..15673
                     /locus_tag="ACHBV5_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFM9967290.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            15680..17347
                     /gene="recN"
                     /locus_tag="ACHBV5_001524"
     CDS             15680..17347
                     /gene="recN"
                     /locus_tag="ACHBV5_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFM9967291.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGVPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLHLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVHFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            17349..18077
                     /locus_tag="ACHBV5_001525"
     CDS             17349..18077
                     /locus_tag="ACHBV5_001525"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HFM9967292.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            18156..19979
                     /gene="lepA"
                     /locus_tag="ACHBV5_001526"
     CDS             18156..19979
                     /gene="lepA"
                     /locus_tag="ACHBV5_001526"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFM9967293.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT         6084 a         3558 c         4668 g         5841 t
ORIGIN      
        1 ttttatattg actgaacacc taaaaagtaa tacaatggtg ttaccattaa aaaagggagc
       61 acaaaagatg actactatta cattaaaagt ttctgaagct gataaaacat ttatgaaagc
      121 aatggctaag tttgaaggag tttccctttc ggaacttatt cgcaccaaaa ctcttgaagc
      181 cctagaagat gaatacgatg ctcgtgtggc agatttagcc tatcaagagt atttagaaga
      241 cttggaaaaa ggagttgaac ccattacttg ggaagaaatg atgcatgatt taggcttgaa
      301 ggatgaataa tttgtataaa ttagttccaa caagacgttt tatcaagcaa ttgaaaaaat
      361 tggaccgtta tacgcagaag ctaattacaa actatttaca aaccaatgtt ttggaagacc
      421 caagacgaca cggaaaggct ttggttggta atcgcgttgg tcaatggcgc tatagaattg
      481 gtaattatcg agttatcgta caaattgtag atgatgaatt agttgttgct actctagaag
      541 ttggtcattg gagagatatt tattgaatta aagctgagta ataacagtat agaaagtaag
      601 gatagtaaaa atttgaataa aaaatggtta tttgcagatt attatgatat aacaattatt
      661 ttacttgctt taatctctgt tattctggta ttacttggat ttgctgagat gattgatttg
      721 gacaatccgc cttatagtat tattgattta gtaatctggg gtgtttttgt aattgattat
      781 agttggcgct tttttattac taaaagaaaa tggcgcttta ttcttgaaaa tatttttgat
      841 ttattgacta ttctcccttt aaatgctatt tttacagtgt ttcgattagg acgtatcttc
      901 cgcttagcaa ggctgacaaa attactgaaa ctgactcgtt tacttagaat aattggactt
      961 acaggtaaat tagaaagaaa aattagtaga ttcttacgaa caaatggatt gatttatatc
     1021 ttgtatgtta atatctttat tgttctagta gggagttcga ttttatccgt tgttgaagaa
     1081 aaatccttct cagatagtct ttggtgggct cttgtgacag taactactgt tggttatggt
     1141 gatattgttc cagtttccct ttttgggaag acgaattatc gagccaaaga atattaatag
     1201 agaaacaatc cgagaagata gaagaactgc atcggatgat acaagatttg cttgaaaaaa
     1261 cataataaaa ataaagatga gacaaagttt gagttgagga gaaatcaagt aagttttgac
     1321 acaatagaac gcatattatc aggtataaaa acttgatact atgcgtttta tagagaaatg
     1381 aaataaaatc tgaacaaatc aattaggaat ttaaagcatt ttataacaac gttttagagt
     1441 aatggggggc tatttcaact tcaacctact ataatacaga aaaaaacaac tccctgataa
     1501 ttcaaggagt tgtctatagt taaattagtt tttagaagct tcttggaatt ctgggttttt
     1561 ccatgcttcg tcaatgatag cttgcaattc tttagcagat gcttgcattt tttgagtttc
     1621 tgcgtcgttc aatgggatat ttactggacg aacaatacca tgtgcaccaa caacagctgg
     1681 ttgaccgata aagacgttct caactccgta ttgaccttct tggaatactg aaagtggaag
     1741 tactgcattt tcatcgtcaa ggattgcttt agtgatacga gcaagggcta ctgcgatacc
     1801 gtagtatgtt gcaccttttt tgttgatgat tgtgtaggct gcatcacgaa caccttcgaa
     1861 caattcaatc aattcagctt cttgaacatt ttgagtatct ttaaggaatt cttcaaggtt
     1921 tacaccagcg atgttagcgt gtgaccaaac agcgaactca gagtcaccgt gttcacccat
     1981 gatgtaggcg tgaactgaac gagcatctac gtccaatttt tcagcaagtg cttgacggaa
     2041 acgagctgag tcaagtgaag tacctgaacc gataacgcgt tctttaggga aaccagagaa
     2101 tttccaagtt gagtaagtca aaacgtcaac tgggttagca gcaacaagga agataccttt
     2161 gaaacctgat tcaacaactt gagttacgat tgatttgttg atagcaaggt ttttacctac
     2221 aaggtcaaga cgagtttcac ctggtttttg aggcgcacct gcagtgatca caacaaggtc
     2281 agcgtctgca cagtcagagt attgagctgc atagattttt ttaggtgaag tgaaggcaag
     2341 ggcgtgacta aggtcaagcg catcaccaac agctttttca tgcaattgtg gaatttcgat
     2401 aattccaagc tcttgtgcaa ttccttggtt aacaagtgca aaagcgtaag atgaacctac
     2461 agcaccatca ccgacaagga taactttttt gtgttgttta gttgaagtca ttgttttaaa
     2521 catctcctta attttattag gggattttcc ctagacaact tcattctatc acttttaaaa
     2581 aactttgtca cgaatatgcc ttatagttct cgatgtaaac gttttagtgg tttagaggct
     2641 gaaatagatg ggaatttatg gtataatgtt gttacttact aattgtgaaa tgaggcattt
     2701 attaatgcag gataaaaatt tagtgaatgt caatctgaca aaggagatga aggcaagttt
     2761 tatcgactac gccatgagtg ttatcgtagc gcgagctctt cctgatgttc gagatggctt
     2821 aaaacctgtt caccgtcgca ttctttacgg aatgaatgaa ttgggtgtga ccccagacaa
     2881 accccataaa aaatctgctc gtattacagg ggatgtcatg ggtaaatatc acccacacgg
     2941 ggattcctct atttatgaag ccatggtccg tatggctcaa tggtggagct accgttacat
     3001 gcttgtagat ggtcatggga attttggttc catggatgga gatagtgctg ccgctcaacg
     3061 ttataccgag gcacgtatga gcaagattgc tctggaaatg cttcgtgata tcaacaaaaa
     3121 tacagttgat ttcgttgata actatgatgc caatgaacgg gaacccttgg tcttgccagc
     3181 gcgttttcca aaccttttgg ttaatggagc aactggtatc gcggttggga tggcaaccaa
     3241 tattccacct cataatctgg gtgaaaccat tgatgcagtg aagttggtca tggataatcc
     3301 tgaagtgact accaaggact tgatggaagt cttgcctgga ccagattttc caactggtgc
     3361 tcttgtcatg gggaaatcag gtatccataa ggcttatgaa acaggtaaag gttcgattgt
     3421 cctacgttct cgtacagaga ttgaaacgac taagactggt cgtgagcgca tcgttgtaac
     3481 agaatttcct tacatggtca ataaaaccaa ggtgcatgag catattgttc gcttggttca
     3541 ggaaaaacgc attgagggta tcacagcagt acgtgatgag tcaaaccgtg aaggtgttcg
     3601 atttgttatt gaagtcaagc gcgacgcctc agccaatgtt attctcaata acctcttcaa
     3661 aatgacccaa atgcaaacca attttggttt caatatgctc gctatccaaa atggtatacc
     3721 gaaaattttg tctcttcgtc agattttgga tgcttatatc gagcaccaaa aagaagtggt
     3781 tgttcgtcgt acacgttttg ataaggaaaa agcggaagcg cgcgctcata tcttagaagg
     3841 tctcttgatt gcgctagacc atatcgacga agtgattcgt atcatccgtg ctagtgaaac
     3901 ggatgcggaa gctcaagctg agttgatgag caagtttaag ctttctgaac gtcaaagtca
     3961 agctatcctt gatatgcgtc ttcgtcgttt gacaggtttg gaacgcgata agattcaatc
     4021 tgagtatgat gacctcttgg ctctgattgc ggatttagca gatattcttg ctaagcctga
     4081 acgtgtttct caaattatca aagacgaatt ggatgaagtt aaacgtaaat tttctgataa
     4141 gcgccgtaca gagttgatga ttggacaggt cttgagtctc gaggatgagg acttgattga
     4201 agaatcggat gtcttgatta ccctttctaa cagaggctac attaagcgtt tggatcagga
     4261 cgagttcact gctcaaaaac gtgggggtcg tggtgtccaa ggaacgggag tgaaagatga
     4321 tgactttgtt cgtgagttag tgtcaactag cacccatgat catctgctct tcttcacaaa
     4381 caagggacgt gtctatcgtc ttaaaggtta tgaaattcct gagtatggtc ggactgccaa
     4441 agggctacca gtagtcaatc tcttgaaatt ggatgaagac gaaagtattc agacggttat
     4501 caatgttgag tctgatcgca gtgatgatgc ttatctcttc tttacaaccc gtcacggtat
     4561 tgtgaagaga actagtgtta aggagtttgc caatattcgt caaaatggtc tcaaagcgct
     4621 gaatttaaag gatgaagatg agttaatcaa tgtcttgttg gcagaaggag atatggatat
     4681 tatcattggt accaagtttg gttatgcagt tcgctttaat caatcagccg ttcgtggtat
     4741 gagtcgtatc gccactggtg tgaaaggtgt taaccttcgt gaaggagaca cagttgttgg
     4801 tgccagcttg attactgatc aagatgaggt tcttattatc acagaaaaag gatatggtaa
     4861 gcgtacagtc gctactgaat acccaacaaa aggtcgtggt ggtaagggaa tgcagacagc
     4921 taaaattacc gaaaaaaatg gcttgctggc cggtcttatg actgttcaag gggatgagga
     4981 tttgatgatt atcactgata caggtgtcat gattcgaacc aatcttgcca atatttcaca
     5041 aacaggacgt gcaactatgg gagttaaagt aatgcgcctg gatcaagatg ctcagatagt
     5101 gactttcaca acggttgcgg tggcagaaaa agaagaagtt gggacagaaa acgaaacaga
     5161 aggtgaagca taatgtctca aaaaaataat aaaaagaaaa acaagcgaaa aaatctgctg
     5221 acaaatatcc tagcaggatt tctgatatta ctgtcactgg ctttgatttt taatactcaa
     5281 attcgaaata ttttcatagt ctggaatacc aataagtatc aagttagcca ggtatcaaaa
     5341 gaaaaattag aagaaaatca ggatacagaa ggcaattttg actttgattc tgtcaaagct
     5401 atctcttcgg aagctgttct aacttctcaa tgggatgctc aaaaattacc agttattggg
     5461 ggaattgcaa ttcctgaatt ggaaatgaat ttgccgattt ttaaaggact tgataatgtt
     5521 aatctcttct acggagctgg tacaatgaaa cgcgagcaag taatgggaga aggaaattat
     5581 agtctagcta gtcaccatat ctttggtgtt gataatgcta ataaaatgtt attttctcct
     5641 ttagataatg ctaaaaatgg catgaagatt tatctaactg ataaaaataa agtttatact
     5701 tatgaaatac gtgaagtcaa acgtgtgaca ccagatcgtg ttgatgaagt tgatgataga
     5761 gatggggtca atgaaatcac attagtaacc tgtgaagacc ttgctgctac agaacgtatt
     5821 attgtcaaag gtgatttgaa agaaacaaaa gattattcac aaacatctga tgaaatccta
     5881 acagctttca atcaaccata taaacaattt tattaataca aatcagtgaa atcatggatt
     5941 tcactgattt tttaagattt tcataaaaat atagtaaaat gaaataagaa taggactaat
     6001 cgttcaggac agtcaaatcg atttctaaca atgttttaga agtagaggtg tactattcta
     6061 gtttcaatct actataaact tttatgaaat acagaaaacg cttcctaaaa cctaaagttt
     6121 gtgatataat tatcaagaaa aaagatttag gagtttatta tgatttcttc agaatttatc
     6181 tcaaagattg aatttgcttg caataagaaa gaaagtcttt atagtcaaag caaatttaag
     6241 tatgcgattc gttcgatatt cgcaggtgca tttttaacct tcagtactgc tgcaggtgca
     6301 gttggggctg acttgattaa taaaattgca ccaggtagtg gacgcttcct ctttccattc
     6361 gtttttgctt ggggcttggc ctacattgtt tttttgaatg ccgagttggt cacttcaaac
     6421 atgatgttct tgactgctgg tagtttctta aaaaaaatct cttggagaaa aacagctgag
     6481 attttactat actgtacctt gttcaacctt atcggatcct tgatagcagg gtggggcttt
     6541 gctcattcgg cagcctatgc gaatctgaca cacgatagtt tcatctcagg tgttgttgag
     6601 atgaagttag gccgctcaaa tgaattggtc ttgcttgagg cgattttggc aaatattttc
     6661 gtaaatattg cgattctgtc atttattttg gtcaaagatg gtggtgccaa actttggctt
     6721 gtgttgtcag ctatttacat gtttgtattc ttaacaaacg agcacattgc ggcgaacttt
     6781 gcttctttcg cgattgtgaa attcagtgtt gctgcggatt caattgccaa cttcggtgtt
     6841 ggaaatatgc ttcgccactg gggtgtgact ttcatcggaa actttatcgg aggaggcctc
     6901 ttgatgggtc ttccatatgc cttcctcaat aaaaacgaag atacttatgt agattaagaa
     6961 aatgagcacg attgagtcgt gcttttttca ttttcaaaat aaggtaatag ctatttctta
     7021 tatcaaaata tagaaaactg atatttgtaa actataactc aaggtgctac aatatcctta
     7081 ataaaataat atggaggtca ccttatgact cgtgatttta aatttgaaac tctacaacta
     7141 catgctggtc aagttgtgac tccagctact gagtctcgtg cagtgccgat ttatcaaaca
     7201 acatcttttg tttttgatga cacgtaggaa ggtgctgatc tgtttgcctt gaggaaacca
     7261 gggaacattt atactcgtat caccaatcct acaacagctg cccttgaagg tggtgttgaa
     7321 gcgctagcaa cagcatcagg tatgactgca gtgacttata cgattttggc gcttgcccat
     7381 gctggtgacc atgtagtggc tgcttcgact atttacggtg gaaccttcaa tcttttgaaa
     7441 gaaccccttc ctcgttatgg tatcacaaca acctttgtcg atattgataa tttggaggaa
     7501 gtagaagcag ctatcaaaga caataccaag cttgtcttga ttgaaacctt gggtaactcc
     7561 ttgattaata ttccagacct ggaaaaactg gcagagattg ctcataaaca tcaaatccca
     7621 cttgtgtcag acaatacttt tgcaacacct tatttgatta acgtcttctc tcatggcgtt
     7681 gacattgcca ttcactctgc gactaagttt atcggtgggc atggtacaac tattggagga
     7741 ataattgtcg atagtggtcg ttttgactgg acggcttcag ggaaattccc tcaatttgtt
     7801 gacgagggtt caagctgcca caatttgagc tatattcgtg atgtgggtgc agcaaccttt
     7861 attatagctg ttcgagttca attgcttcgt gatacaggtg cagccttgtc accattcaat
     7921 gctttcctct tgctacaaag acttgaaact ctttcacttc gtgtggaacg ccatgtacaa
     7981 aatgctgaga caattgttga ttttcttgtc aaccatccta aggtagaaaa ggtaaattat
     8041 ccaaaacttg cagatagtcc ttatcatgcc ttggctgaga aatacttgcc aaaaggtgtc
     8101 ggttcaatct ttaccttcca cgtcaaaggt gacgaggaag aagcacgcaa ggtcattgat
     8161 aatttagaaa tcttttctga ccttgcaaac gcggcagatg ctaaatcgct tgttgtccat
     8221 ccagcaacaa ccactcacgg tcaattgtca gaaaaagacc tagaagcagc aggtgtcaca
     8281 ccaaaccaaa ttcgtctgtc aatcggtctt gaaaatgtag aagatttgat tgaagactta
     8341 cgcttggcct tggaaaaaat ttaaagtaaa agaagataaa cagtgggttt tgactcactg
     8401 tttttgattt tccctcaggc atgatataat ggttacagaa gtctagaaag aggaatgtaa
     8461 tgaacgaaat caaatgtccc aactgtgggg aagtctttac agtaaatgaa agccagtatg
     8521 ctgaactttt gtcccaagtg agaacggcag agtttgataa ggaactacac gataggatga
     8581 ggcaggaact ggccttggct gagcaaaagg ctatgaatga gcaacagact aaactggctc
     8641 agaaggatca agaaattgcg caattacaga gtcagatcca aaactttgat acagaaaaag
     8701 aattggccaa gaaagaggtt gaacagacaa gccatgaggc tctcttggct aaggacaagg
     8761 aagtacagct cttagaaaat cagttggcta ccttgcgttt ggagcatgaa aatcaactac
     8821 aaaagaccct ttctgaccta gaaaaagaac gggatcaggt taaaaaccaa ctacttttgc
     8881 aggaaaagga aaatgaatta tctttggctt ctgttaagca aaactacgaa gcccagctca
     8941 aggcagctag tgaacaagtc gagttttata agaattttaa ggctcaacaa tctacaaaag
     9001 cgattgggga aagcctagaa cagtatgcag agagtgagtt taacaaggtt cgtagtttcg
     9061 cctttccaaa tgcttacttt gagaaggata acaaggtctc ttcgcgtggg tctaaagggg
     9121 actttatctt ccgtgagtgt gatgaaaatg gagttgaaat catttctatc atgtttgaga
     9181 tgaaaaacga agcggacgga acagagaaga agcacaagaa tgcagatttt tacaaggaat
     9241 tggacaagga ccgtcgggag aagaactgtg agtatgccgt tttggtgacc atgcttgagg
     9301 ctgataatga ctactttaac acagggattg ttgacgtcag tcacgagtat gaaaaaatgt
     9361 atgttgttcg tcctcaattc tttatccaat tgattggtct cttacgtaat gcggcgctaa
     9421 attccctaaa atacaagcag gagttggcct tggttcgcga gcaaaatatt gacattacgc
     9481 attttgagga agatttggat gcctttaagc tagcttttgc taagaactat aattcagctt
     9541 cgactaactt tggaaaagct attgatgaaa tcgacaaggc catcaaacgc atggaagagg
     9601 ttaagaaatt cctgaccaca tctgaaaacc aactccgttt agctaacaac aaattggaag
     9661 atgtctctgt taaaaaattg acccggaaaa atccaacaat gaaagcgaag ttcgaagcac
     9721 tgaaggggga gtagaaagca aaaatgaacg gtattattaa cttaaaaaag gaagcaggaa
     9781 tgacctcgca tgatgcggtt tttaaactgc gtaagatttt gggaaccaag aaaattggtc
     9841 atggtggaac cttggatccg gatgtggtgg gtgttttgcc gattgcggtt ggcaaggcga
     9901 cacgcatggt cgagtttatg caggacgagg gtaagatcta tgagggggaa atcactctgg
     9961 gctattccac gaagactgag gatgctagtg gggaagtggt cgcagaaacc cctgttttgt
    10021 ctctcttgga tgaaaagctt gttgatgaag cgattgctag cttgactggg cctattactc
    10081 agattccccc tatgtattcg gcagttaagg ttaatggtcg caagctctat gagtatgcgc
    10141 gtgctggtca ggaagtggag cgtccagaac gtcaggtgac catttatcaa tttgagcgaa
    10201 caagtccgat ttcttatgat ggccaacttg cccgattcac ttttcgtgta aaatgcagta
    10261 aagggacgta catccgtact ttgtcagttg atttgggtga aaagcttggt tatgcggctc
    10321 atatgtccca tttgactcgt actagtgctg ctggcttaca attagaagac gctcttgcct
    10381 tggaggaaat tgctgaaaaa gtagaggctg ggcaattaga ttttctccat cctttagaga
    10441 ttgggacagg tgaccttgtc aaagttttcc taactccaga agaggctaca gaagttcgct
    10501 ttggtcgttt tattgagcta gaccaaacgg acaaagaact ggctgccttt gaagatgata
    10561 aattgttagc cattctagaa aaacggggca atctctataa gccaaggaag gtttttagct
    10621 agatcgttta ggaataaaaa tcgggtgata gataacaatt gcttgataaa accccatact
    10681 aatagtagaa tggttttggg aattataata ttccaattgt tgcgagttgt aggtactcaa
    10741 ataatctata tagaaattta gaggtgtgaa atgaagcaat ttaaaattct ttcagataaa
    10801 tatttagagt ccattacagg ttctgatggg aacttaggcc caggatttgg tgtgataatt
    10861 ccatgatgcg aaatgagttt cgagaaaggg tggagcaact tcttcaacaa aaagaaataa
    10921 atgaaaatag tgagttgagt cacctgtttc gtcttgctat acaaaattta gacagaaatg
    10981 aaaaatacca atcggtcatg gccaatttga gtcaagggtt gtcactttac ctcatgacgc
    11041 atcattacca ggcacctaag tctgtcattg attttggttt atggattgcc aaagctccta
    11101 gccaggaaag agggagactg gctttcttgc agatgcttgc tcaaacccta cagggctttc
    11161 gttaaaactg tcgaacatca gagggaagac tctggtgttt tttgctgatg agactataaa
    11221 ttttgtaaaa aatgtgatag aatagacgac ggataaaata acggaggata gcatgcaaaa
    11281 tagaccaatc attattggag tgacaggtgg ttctggtggt ggtaaaacca gtgtttcaag
    11341 agccatttta tcgcattttc ctgatgaaaa gatttccatg attgagcatg attcatacta
    11401 caaggatcag tctcatttga cctttgaaga gcgtgtcaaa accaactatg accatccttt
    11461 tgcctttgat acagacttga tgatcgagca gattaaggaa ttgttggcag ggcgtccggt
    11521 ggacatcccg acctacgact atacagagca tacacggagt agcaagacct atcgtcagga
    11581 acctcaagat gtctttatcg ttgagggtat tttggtcttg gaggacaagc gtctgcgcga
    11641 tttgatggat atcaagattt ttgtggatac ggatgacgat gtgcgcatta ttcgtcgtat
    11701 caagcgtgat atggaggagc gtggccgtag ccttgatagc gttattaacc agtacttagg
    11761 tgtggtcaaa ccaatgtacc accagtttat cgagtcaact aagcgttatg ctgatatcgt
    11821 cattcctgaa ggggttagca ataccgtggc tatcgacctg ttgacgacca agattgcaaa
    11881 gattttggaa gaagctcgaa acagcaaata atcacatgtg gaggccttgc ctcctttttc
    11941 tatttttccc tcataatggt acataaatgg agatttttag gcatattttt ggtataataa
    12001 tacccatgaa agagcaagta aatgaatagt aggtggagat ggaaaagtat ttatcggtaa
    12061 caactttgac caagtatctg aaaatgaaat tcgataaaga cccatacttg gaacgggtct
    12121 atttaactgg tcaagtttcc aactttcgta aacgacctac tcaccaatat ttctccctaa
    12181 aggatgacca tgcagttatt caagcgacca tctggtctgg gatttatcag aaattagggt
    12241 ttgacctgga agaaggaatg aagatcaatg tgattgggcg tgtacaggtc tatgaaccaa
    12301 gtggtagcta ctccatcatc attgaaaaag ctgagcctga tggggttggg gcgcttgcga
    12361 ttcagtttga acaacttaag aaaaaattga cagaagaagg cctgtttcaa gaacgcttca
    12421 agcaagctct gccccaattt tctaagagaa ttggtgtagt aaccagccgt agtggagccg
    12481 ttattcgaga tattatcacg accgtcagca ggcgattccc aggtgttgac atccttcttt
    12541 atccgaccaa ggttcaaggt gaaggggctg cggaggaaat tgctagaaat attgcgcgtg
    12601 ctaatcaacg ggacgatttg gatttgctca ttattggtcg tggaggtggt tctattgagg
    12661 atctctgggc ctttaacgaa gaaattgtgg tacgagctat ttttgaatct cgtttgccag
    12721 ttatctctag tgtggggcat gagacggatg tgaccttggc agattttgtg gcagatcgac
    12781 gcgctgcaac gccaacagcg gcggctgaac tggcaacacc tgtgaccaag ttggatgtat
    12841 tagctcattt gcaaaatcag gaaaaacgga tggtaacggc agtccgaaat gttctatcta
    12901 agaaacaaga ggctttgaaa aaatgcagtc agtctgttat ctttagacaa cctgagcgct
    12961 tgtatgacgg ttatttgcaa cgcttggacc aactgcaact gcgtttgaaa caaagtttgc
    13021 gaactcggat ttctgataac aaacaattag ttcaagcaag aactcatcaa ttagtacaat
    13081 tatcacctgt taccaaaatc caacgctatc aagaccgttt aggacagttg gacaagctct
    13141 taggtagcca aatggcgtta gtttatgacg ccaaggttgc tgaggccaag cgactttcgg
    13201 aagctttgct catgttggat actagccgaa tcgtggcgcg tggttatgct attgtcaaaa
    13261 aagaagagtc cgttgtagat tcggttgaga gtttgaagaa aaaagaccaa gtaacgcttt
    13321 tgatgcgaga tggtcaagta gaattagagg ttaaagatgt caaaacaaaa gaaatttgag
    13381 gaaaatctag cagaactgga aaccattgtc caaagtttgg aaaatggtga aattgctctg
    13441 gaagatgcga ttactgcctt tcaaaagggc atggtcttgt caaaagagct ccaagctacg
    13501 ctggacaagg ctgaaaagac cttggtcaag gtcatgcaag aagacggaac agaaagtgat
    13561 tttgaatgaa aaagcaagaa aaattagctc ttgtcgagtc ggctttggaa gatttttatg
    13621 gagaccagca gtttgcctct agtttacggg agtctgttct ctattctatt catgctggtg
    13681 gcaagcgtat tcggcctttt ctcttgttag aagttctgga agccttgcag gttaccatca
    13741 aacctgctca cgcgcaggta gctactgcct tagagatgat tcatacaggg agcttgattc
    13801 acgatgacct tcctgctatg gatgatgacg attatcgaag agggcggtta accaatcaca
    13861 agaaattcgg tgaagctatg gccattttgg ctggagatgc tttattctta gacccatatg
    13921 ccttgattgc gcaggcagat ttgccaagtc agatcaaggt ggacttgatt gccaacttat
    13981 cccttgcttc aggtagtctg ggtatggtgg cagggcaagt tttggatatg gagggcgaac
    14041 accagcactt gtctctggaa gaacttcaga ctattcatgc caataagact gggaagttac
    14101 tagcctatcc cttccaagcg gcagctatta tagctgaatt gtcacctgaa atgcaggtga
    14161 agctgaaaac tgtgggtgaa ttgattggac ttgcttttca agtcagagat gatgtactgg
    14221 atgtgacagc tagttttgag gaaatcggca agacacctca aaaggatctg caggcagaaa
    14281 aatcaaccta tcctgccttg ttgggcttgg aagagtccat tgccttttgt aaccaaaccc
    14341 tggatcaagc taatgaaaaa ttagaagaaa ttgcccagca gcttcccttt gaaacagaat
    14401 cgattgtaag tgtagtagaa agtttgagaa tcaatggcta aggaaagagt ggatgtacta
    14461 gcttataaac aggggttgtt tgaaacgaga gagcaggcca agcgaggtgt gatggctggc
    14521 ctagtcgtag cagtccttaa tggagaacgg tttgacaagc caggagagaa aattccagat
    14581 gacaccgaat taaaactcaa gggggagaaa ctcaagtatg tcagccgtgg tggtttgaaa
    14641 ctggaaaagg ccttgcaggt ctttgatttg tcggtggatg gcgcgactac gattgatatc
    14701 ggggcctcta ctggaggttt taccgatgtc atgctacaga atagtgccaa gttggtcttt
    14761 gcagtcgatg ttgggaccaa tcagttggct tggaaattac gccaagaccc acgagttgtc
    14821 agcatggagc agttcaattt ccgctatgct gaaaagactg atttcgagca ggagccgagc
    14881 tttgccagta ttgatgtgag tttcatttcc cttagtctga ttttgccagc cttgcaccgt
    14941 gtcttggctg atcaaggtca ggtggtagca cttgtcaaac ctcagtttga ggcaggacgt
    15001 gagcagattg ggaaaaatgg aattattcga gatgttaaga ttcatcagaa tgtccttgaa
    15061 tctgtaacag ctatggcagt agaggcaggt ttttcagtcc ttggcttgga cttttctccc
    15121 atccaaggtg gacatggaaa tattgaattt ttagcgtatt tgaaaaaaga aaagtcagca
    15181 agcaatcaga ttcttgctga gattaaagaa gcagtagaga gggcgcatag tcaatttaaa
    15241 aatgaataaa aaagaaagac ttgaaaaaat tagaagattg gtgacagatt atcaaatcgg
    15301 cacgcaagaa gaaattgtag aacatttgaa agaagcaggt atcactgcca ctcaggcgac
    15361 ggtatcccga gatatcaaag agttaggtat tgtcaaaatt cctttgagag acaacaccta
    15421 tgtctacgaa ttaccaaaat caatcgtaaa aagtctgcaa ctggctgaag acaatatcga
    15481 atcggctgaa ttgatggata agatgatcaa tctccaagtt attccaggaa atacggcttt
    15541 tgtaaaagct cagttaatcg agacttttgc agacaagatt tttagctgtt tgactgatga
    15601 tagctcgatt ttagtcattg ccagaagtgg aagtctagca gaggaaatct ttgaacaagt
    15661 aaaaaattgg taggtctata tgttacttga aatttcgata aaaaactttg ccattattga
    15721 ggctatttcc ctcaattttg aaaaggggat gactgtcctg actggtgaaa cgggtgcagg
    15781 gaagtcgatt atcattgatg ccatgaatat gatgttggga gctcgtgcga cgacagatgt
    15841 tattcgtcat ggtgtaccaa aggcagagat tgaggggctt ttctcagttg agaatagtcg
    15901 tcttttacag gaaatttttg atgagcaagg tttagaatta ggtgatgaaa ttatcatccg
    15961 tcgggaaatc ttgcaaaatg gtcgtagtat cagccgtgta aatggtcaga tggttaatct
    16021 gtctgttttg cgagctattg ggcaacatct tgtagatatt catggtcagc atgaccatga
    16081 ggagttaatg cgtccccaac tgcatatcca gatgttggat gaatttggtg atgccgcttt
    16141 ttgggacttg aaagaaacct atcaaacgag ttttgatgcc tatcggaaaa tgcgcaagca
    16201 ggttctggaa gtcaagaaaa accaacagga acacaaggca cgtatcgaaa tgttggaatt
    16261 tcaaatggca gagattgagg cagcaaactt gcaggctgga gaagacttgg ctctcaatca
    16321 agagcgagat aaactcctca accacaaaaa tattgcggat acactgacca atgcctacag
    16381 tatgttggac aatgaagatt tttcaagtct ggccaatgtt cgttcagcca tgaatgacat
    16441 ggaaagtgtc gaagagtatg accctgaata ccgtgaaatt tcaagctctc tgtctgagac
    16501 ctactatgtt ttagaagaca ttagcaaacg tttggaagct atcattgagg accttgattt
    16561 tgatggcaat cgcctcatgc aggttgagaa tcgtttgcac ctccttcata ctattactcg
    16621 taagtatggt gggactgttg atgatgtttt gctttatttt gccaagatta cggaagaata
    16681 caatctcttg acaggcaata atctttcgtc tgaggacatg gaagcagagc ttaagaagtt
    16741 ggaagtcaat cttgtcaatt tggcaggtca acttgcttct gctcgtcata atttggctca
    16801 gcaactcgaa gctgagatta aacaagaact gcaagatctt tatatggaaa aagcccagtt
    16861 tcaggttcat tttagtaagg gaaaattcag tcgtggggga aatgaaatgg ttgagtttta
    16921 tatttcaacc aaccctggag aagactttaa acccttggtt aaggttgctt ctggagggga
    16981 attatctcgt ctcatgttag ccattaagtc tgccttttca cgtaaagaag gcaagactag
    17041 cattgtcttt gatgaggtgg atacgggagt ttcaggtcgt gttgctcaag ctattgctca
    17101 gaaaattcat aaaattggtc agcatggtca ggttttggct atctcccatt tgccacaagt
    17161 aattgcgatt gcagattatc aattctttat tgagaagatt agtaatgacc attcaacggt
    17221 ttcgactgtt cgtctcttga cagtcgaaga gcgagtggag gaagttgcca agatgttggc
    17281 aggtgatgat gtgacagaag cagccctgac gcaagccaga gaattgttga gaaacaggga
    17341 gaaataagat gacagattat tatgtaattg gagatgttca cggaaaagct gggatgctgg
    17401 aagaccttct taaaacctgg gatggtcaga cccagttgct ctttctaggt gatttgattg
    17461 acagaggtga ggatagtcac cgtgttcttg aaatggtcaa ggacttggtg gacaatcaag
    17521 gggctatctg tttgtctgga aaccacgagt atatgttttt gacttggcta gatgacccag
    17581 aagaaagtta tgaccattat cgtcgcaatg gtggagatac aaccattaac tctatcctag
    17641 gtcgtccctt ggatgcacca gttgatggag tagaagatgc caagcgggtt gccgctgaag
    17701 cgtcagactt ggtcgaattc attcgtcaaa tgccatttgt agtagagaca gacaagtata
    17761 tatttgttca cgcaggtatt gatttgactt tggacgactg gcatgaaaca acagattata
    17821 aaaaagtatg gcttagaaaa ccattccacg gagctgaaaa tcatactgga aaaaccattg
    17881 tcttcggtca tacaccggtc tatggtttgt tacagcaaga acgcggtaca tctgagcttt
    17941 ggactacaga agatggcaag attggaatgg atggaggagc tgtttatggt ggtgtccttc
    18001 acgggattgt ctttacagac caaggaatga cagaacacca ctttatcgaa aatgacggct
    18061 ttgtcgctga agattagtac tcctagcagg gtatggtctt gtcaaaatat caaaaacaat
    18121 ttataataaa tagataccct gaaaggaaga gaatcatgaa cttagaagaa ttgaaaaaac
    18181 gacaggggaa gatccgtaac ttctctatta tcgcccatat tgaccacggg aaatcaactc
    18241 tagcagaccg cattttggaa aaaacagaga cggtttcaag tcgtgaaatg caggcccagc
    18301 ttttggatag catggatcta gagcgggaac gtggaattac tattaagttg aatgccatcg
    18361 agttgaatta cactgcaaaa gatggggaaa cttatatttt ccacttgatt gacacaccag
    18421 ggcacgttga ctttacctat gaagtttcac gttcgctagc tgcctgtgag ggtgctattt
    18481 tggtggtcga tgcggctcaa ggaattgagg ctcaaactct tgccaacgtt tatctggctt
    18541 tggataatga tttggaaatc atgcctatca ttaataaaat tgacctgccg gctgcagatc
    18601 cggagagcgt gcgtacagag attgaagatg tgattggttt ggatgccagt gaagcagttt
    18661 tggcttctgc caaggctggt attgggattg aagaaatcct cgagcaaatt gtagaaaaag
    18721 taccagcacc aacgggtgat gtgacggcgc cacttaaggc cttgattttc gactctgttt
    18781 acgatgctta ccgtggggtt atcctccaag tgcgtgtcat ggacggagtg gtcaaacctg
    18841 gtgataagat tcagctcatg agcaatagta agacctttga tgtggccgaa gtcggtattt
    18901 ttacaccaaa agcggttggt cgtgatttcc ttgcgactgg tgatgttggt tacattgcgg
    18961 cgtctatcaa gacggttcag gatactcgtg tgggtgatac cgttaccttg gcaaccaatc
    19021 ctgcggcaga accattacat ggttataagc agatgaatcc tatggtcttt gcgggtctct
    19081 acccaatcga atcaaacaag tacaatgacc tgcgtgaagc gcttgaaaaa ttgcaactga
    19141 atgatgctag tcttcagttt gaaccagaaa catctcaggc acttggattt ggtttccgtt
    19201 gtggatttct tggacttctc catatggatg ttatccagga acgtttagag cgtgagttca
    19261 atattgatct catcatgaca gctccgtctg ttatttacaa agttaatttg accgacggtg
    19321 agtctatgga tgtgtctaac ccatctgagt ttccagaccc aactaagatt gcgaccattg
    19381 aagagcctta tgtcaaggcg caaatcatgg taccacagga gttcgtcgga gcagtaatgg
    19441 agctagctca gcgtaagcgt ggggactttg tgactatgga ctatattgat gataaccgtg
    19501 tcaatgttat ctatcaaatt cctcttgctg aaatcgtctt tgacttcttt gataaactta
    19561 agtcttcgac acgtggttat gcaagttttg actacgaatt gtcagaatat cgcccatcta
    19621 agctagtgaa aatggatatc cttctcaacg gagacaaggt ggatgccctc agctttatcg
    19681 ttcataagga ctttgcttat gaacgtggga aactcatcgt tgataagctc aagaaaatca
    19741 tccctcgcca acaatttgag gttccaatcc aagcggctat tggacacaag attgtcgctc
    19801 gtactgatat caaggccctt cgtaagaacg tacttgctaa atgttatggt ggtgacgttt
    19861 ctcgtaagcg taaactcctt gaaaaacaaa aagctggtaa gaaacgcatg aaatccatcg
    19921 gatcagttga agttccgcaa gaagccttcc tcagcgtctt gagtatggat gaagaataag
    19981 ttatcagaaa tgcctttcct tgttcacagg aaatttatat aagaatcaat agtaaagcag
    20041 gcttagatgg tctgcttttt tagtttttat actcttcgaa aatctcttca aaccacgtca
    20101 gcgtcgcctt accgtatgta tggttactga cttcgtcagt ttcatctaca a
//
LOCUS       DAYYYC010000041        20063 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.041, whole genome shotgun sequence.
ACCESSION   DAYYYC010000041 DAYYYC010000000
VERSION     DAYYYC010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20063
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.041"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..1188
                     /locus_tag="ACHBV5_001527"
     CDS             <1..1188
                     /locus_tag="ACHBV5_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4365 domain-containing protein"
                     /protein_id="HFM9967294.1"
                     /translation="NYQEEHDLFIYYLDPITGIEIPLENTIKIVETEEETDLIIKIGD
                     YVFQDVKRHRFPDGSVQLHFGESFTMSFDIKKKQFKFNYTRPDLLSKAIKCTQVFQEL
                     GKIGYFTLNGNKIELDERSIKDISSLDLEADIKGLLKISNFMKKMGIQKDVDLSCFDK
                     QSQRNLNILYSGLVLKKKVALNYNESKLLHLNIANIHIITLYSFLSDKNGTMIDIFTE
                     TPWCREGETEDEDYLDISIFEVFEPNDWLKIDNCKIDSVIASYQRLVDNKLKYEGADR
                     TILKIVIAADMAEDKTKRELLLNWAQCLSDWNLKYSKNCEMAIINDLQIKSRVRKLNS
                     KETETLTNILVNSNDNYELCFGSSVLLKSKPQADLFWNKLDNETKERYKDFPIYTLYM
                     KLS"
     gene            complement(1399..2205)
                     /gene="yidA"
                     /locus_tag="ACHBV5_001528"
     CDS             complement(1399..2205)
                     /gene="yidA"
                     /locus_tag="ACHBV5_001528"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFM9967295.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDEGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMADKEIVKCMFIDEPE
                     ILDATIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(2218..3522)
                     /locus_tag="ACHBV5_001529"
     CDS             complement(2218..3522)
                     /locus_tag="ACHBV5_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFM9967296.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            3594..3971
                     /locus_tag="ACHBV5_001530"
     CDS             3594..3971
                     /locus_tag="ACHBV5_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFM9967297.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSRYQVDGQKIE
                     LAYQLQNQEGHPFASYQLEITWG"
     gene            4061..4393
                     /locus_tag="ACHBV5_001531"
     CDS             4061..4393
                     /locus_tag="ACHBV5_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFM9967298.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            4405..5976
                     /gene="ffh"
                     /locus_tag="ACHBV5_001532"
     CDS             4405..5976
                     /gene="ffh"
                     /locus_tag="ACHBV5_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFM9967299.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(6171..7454)
                     /locus_tag="ACHBV5_001533"
     CDS             complement(6171..7454)
                     /locus_tag="ACHBV5_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFM9967300.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMLATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTSGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(7708..8421)
                     /gene="rsmG"
                     /locus_tag="ACHBV5_001534"
     CDS             complement(7708..8421)
                     /gene="rsmG"
                     /locus_tag="ACHBV5_001534"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFM9967301.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            8515..9075
                     /locus_tag="ACHBV5_001535"
     CDS             8515..9075
                     /locus_tag="ACHBV5_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HFM9967302.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            9077..9976
                     /gene="htpX"
                     /locus_tag="ACHBV5_001536"
     CDS             9077..9976
                     /gene="htpX"
                     /locus_tag="ACHBV5_001536"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HFM9967303.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(10125..11684)
                     /locus_tag="ACHBV5_001537"
     CDS             complement(10125..11684)
                     /locus_tag="ACHBV5_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFM9967304.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEICSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(11923..12240)
                     /locus_tag="ACHBV5_001538"
     CDS             complement(11923..12240)
                     /locus_tag="ACHBV5_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HFM9967305.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FGF"
     gene            12410..12952
                     /locus_tag="ACHBV5_001539"
     CDS             12410..12952
                     /locus_tag="ACHBV5_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFM9967306.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            12952..13581
                     /gene="nth"
                     /locus_tag="ACHBV5_001540"
     CDS             12952..13581
                     /gene="nth"
                     /locus_tag="ACHBV5_001540"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFM9967307.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            13792..14313
                     /gene="pyrR"
                     /locus_tag="ACHBV5_001541"
     CDS             13792..14313
                     /gene="pyrR"
                     /locus_tag="ACHBV5_001541"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFM9967308.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            14332..15255
                     /locus_tag="ACHBV5_001542"
     CDS             14332..15255
                     /locus_tag="ACHBV5_001542"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFM9967309.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            15305..16384
                     /locus_tag="ACHBV5_001543"
     CDS             15305..16384
                     /locus_tag="ACHBV5_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFM9967310.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            16697..19873
                     /gene="carB"
                     /locus_tag="ACHBV5_001544"
     CDS             16697..19873
                     /gene="carB"
                     /locus_tag="ACHBV5_001544"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFM9967311.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDTLIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIKSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         5962 a         3786 c         4414 g         5901 t
ORIGIN      
        1 aactatcagg aagaacatga tctctttatt tattatttag atcctataac tggcatagaa
       61 atacctcttg aaaacacaat aaagattgta gaaactgaag aagaaacgga tttaattata
      121 aaaataggcg attatgtttt tcaagacgta aaaagacatc gttttcctga tgggagtgta
      181 cagcttcatt ttggtgaaag ctttacaatg tcttttgaca taaagaagaa acaattcaaa
      241 tttaactata ctaggccgga tttgctgtca aaagctataa agtgtactca ggtatttcaa
      301 gagctaggaa aaatcggata ttttaccctt aatggtaata aaatagagtt agatgaacgg
      361 tcaataaagg atatttcttc acttgattta gaggctgata taaagggatt gttaaaaatt
      421 tctaacttta tgaaaaaaat gggtatacaa aaagatgttg atttatcttg ctttgataaa
      481 caatctcaaa gaaatctaaa tattctttat tcaggtcttg tcttaaaaaa gaaagttgct
      541 ttaaattata atgaatcgaa attacttcac ctaaatattg ctaacatcca cattataact
      601 ttatatagtt ttttgtcaga taaaaatgga actatgatag acatttttac tgaaactcct
      661 tggtgccggg aaggagaaac tgaagatgaa gattatttag acatttcaat ttttgaagta
      721 tttgaaccaa acgattggct aaaaattgat aattgtaaaa ttgattcagt tattgcctcg
      781 tatcaaagat tggtagataa taagctgaaa tatgaaggcg ctgaccgtac tattttaaaa
      841 atagttatcg ctgcagacat ggcagaagat aagactaaaa gagagttgtt acttaattgg
      901 gcgcaatgtc tttctgactg gaacttaaaa tactcaaaaa attgtgagat ggctataata
      961 aatgaccttc aaataaaatc tagagttcgt aaattaaaca gcaaagaaac agagacacta
     1021 actaatattt tagtaaatag taatgataac tatgaacttt gtttcggttc atcagtgcta
     1081 ttaaaatcga aaccacaagc tgatttgttt tggaataaac tggataatga gacaaaagaa
     1141 agatataagg actttcctat ttatactttg tatatgaaat tatcgtaaaa ttaaaagaga
     1201 ttataaagag ataacatata gaaatagaga gtgatttatt acaattcagt accacaaatt
     1261 aagaaagcaa tgcctatttt ttgtactctc aagatttaag taactgtaca actgcaatta
     1321 aatttattaa tttactctca ttgtgatata ttcatacaaa aaccgctcag ctgagcggtt
     1381 ttagtctatt ctttcctttt acagtaccca tgttcggatg gcgtgggcaa cgccggattc
     1441 gtcatttgtt ttagtgatgt atttggcgat ttttttgatt tctggatttc cattttccat
     1501 gacaacgggg tttccaacga cttccagcat ggcacggtca ttttcttcgt caccgattgc
     1561 catggtttca tctttggtca atccgagttt ttcagccaag tgagtaatgg ctgaaccctt
     1621 gtctacattc tttgtaagga gttcgaggta gaaaggagca gatttgttga tggagtagcg
     1681 ctcgtaaaat tctgctggaa ttttttcaat cgtagcatcg aggatttctg gttcatcgat
     1741 gaacatacat ttgacaattt ccttgtcagc catttcttca ggtgtacggt agaagatagg
     1801 catgctgacg agggttgatt cgtgcacagt gtattttccg atattgcgat tggcagtata
     1861 gataccgtcc ttggtaatgg cgtgcatgtg gacaccgagc ttgcggctga gaaattccat
     1921 atctagataa tcctcataag tcaaggattc gctgataatc tcatgtcctg tagcagtttc
     1981 ttggacaagg gcaccgttga aggttaccac atagtccccc tcgtctctca actgcaagtc
     2041 gtctagaagt ttggcaacgc ctgcgatagg gcggccagtt gcaatcacga ctttgacacc
     2101 agcttctttg gcatcttgga tggcagaaaa gacttcagga gtgatttcct tttggctgtt
     2161 gactagggtt ccgtcaatat cgacggcgat tagtttaata ctcataaatt tcctctttta
     2221 gtttttattt ggggtaaaat gatcgttctc aatcaagtgt aaaaattgct gggtgatgct
     2281 tgcgaagatg ctgttttggt ctaacatttc tttcgggaaa taaaagcgat tatctccgtg
     2341 gcgacttcca gcaagggatt ggacgatagg ggacaggcta gagagttctg ccagttctcc
     2401 atttttttgt aaaatctcaa tctgtgtcct tggattttca gattcgggac ggtaaatatc
     2461 ataagggagg tcaaagttct tatgaatggc agtatagtag tcgggatcaa agccgatgtc
     2521 ctcaaccaat tttctcatgc tagcgagttg gtcttggtct tcttgtgaaa aggtaatgga
     2581 tttaaagacc ttgcggttga caaagcgatg cgataaatct gcaagaatct tgtcaggact
     2641 ggtcatccag agttggaagt aggtattcat cacaccatca tccagagcca gatagtcagt
     2701 caaggtcaca tttttttcga agaaaggcag gaggtgtgga gaagttcggg caaagaaatc
     2761 cttgtcctca ggatagagtt ccttggcgcg tttgagaaga ttctgtagga gaacttccat
     2821 ggcgcgtgtt gcggggtgga aataaacctg catgtacatc tggtagcgac tgaggacgta
     2881 gtcttcgatg gcgtgcatgc cattgcgctg aaaggcgata ccattttcga taggacgaat
     2941 gactcggagg attcgagtca ggtcaaattc cccataggat gctcctgtaa aataggagtc
     3001 gcgcaagaga tagtccatgc gatctgcgtc aatctgacta gaaatgagct gcacgacctg
     3061 cttgttagga taggtatggt ctatgacact ggcaactttc tctggaaaat cgggcgctac
     3121 ttgtagcagg acttggtgaa tctctgtctc aggattttga ataatctcct gagtaatggc
     3181 ttcatggtct gtatcaaaga gattttcaaa agtatgggag taggcaccat gcccaaggtc
     3241 gtgtaggaga gcagcggtca tggtcaagag agactcggca ggattccatt cctcaggata
     3301 tttttcttcg aaaatctctg tgatgcgtcg tgcaatttca tagactccta gacagtgaga
     3361 gaagcgactg tgttctccac cgtggaaggt ataactggaa gttcccagtt gtttgatccg
     3421 gcgcaaacgc tgaaattctt ttgtattaat caagtcatag atgatttgat tattgacatg
     3481 gatgtagttg tgaacagggt cacggaatac tttttcgttc atatgaccat tatagcaaaa
     3541 tcctgctctt tttggtaaaa tagtaggaca agagacaaga aagagggcct gatgtgaaga
     3601 ttcggatgcg aaatacaatt cagtttgatg agcagttgga agtgattgac cagctttatg
     3661 atgtggaagt gcatgaaaaa ggagattata gctacctgct tttctataat gaggaaaagg
     3721 aaaaagtagt gattaaattt catggtcaag aacttatgat gagccgattt tccaatccca
     3781 agaccattat gcgcttttta aaggatagtg atagtttggc ctatattcct acccctatgg
     3841 gcatgcagga atttatcatt caaacgagcc gttatcaagt agatgggcaa aagattgagc
     3901 tagcttatca actacaaaat caagaggggc atccctttgc cagctatcaa ttggaaatta
     3961 cttggggcta ggatctcgtt tttctcaaat ctactttcta tcttcaagga ttggctccct
     4021 agtgtggtag attaggctat tttttggtat aataaaagtt atggaaatcg aaaaaaccaa
     4081 tcgtatgaat gcgctctttg aattttatgc ggcgcttttg acagataagc aaatgaatta
     4141 tatcgagctt tactacgctg atgattacag tcttgctgag atagctgagg agtttggtgt
     4201 tagtcgtcag gctgtctatg acaatatcaa gcgaacagaa aagattctgg aagattatga
     4261 gatgaaattg cacatgtact cggactacat tgtccgtagt cagatttttg accaaatctt
     4321 ggagcgctat cccaaggatg attttctgca ggagcagata gaaattttaa caagcattga
     4381 taatagagaa taagaggaag aaaaatggca tttgaaagtt taacagaacg tttgcagaac
     4441 gtctttaaaa atctacgtaa aaaaggaaaa atctctgaat ctgatgtcca agaggcaacc
     4501 aaagaaattc gcttggcctt gctcgaggcc gacgttgcct tgcctgttgt aaaggacttt
     4561 atcaagaaag ttcgtgagcg tgcagtcggg catgaggtca ttgatacact taatcctgcg
     4621 caacagatta ttaaaatcgt tgatgaggaa ctgacagccg ttttaggttc tgatacggca
     4681 gaaattatca agtcacctaa gattccaacc atcatcatga tggttggttt acaaggggct
     4741 ggtaaaacaa cctttgctgg taaattggcc aacaaactca agaaagaaga aaatgctcgt
     4801 cctttgatga ttgcggcgga tatttatcgt ccagctgcca ttgaccagct taagaccttg
     4861 ggacaacaga ttgatgtgcc tgtctttgca cttggaacag aagtaccagc tgttgagatt
     4921 gtacgtcaag gtttggagca agcccaaact aatcataacg actatgtctt gattgatact
     4981 gcgggtcgtt tgcagattga tgagctcctc atgaatgagc ttcgtgatgt gaaagcattg
     5041 gctcaaccaa atgaaatctt gcttgtcgtt gatgctatga ttggtcagga agcagccaat
     5101 gttgcgcgtg agtttaatgc tcagttggaa gtgactgggg tcatccttac caagattgat
     5161 ggcgatactc gtggtggtgc tgctctgtct gttcgtcaca ttactggaaa accaatcaag
     5221 ttcactggta caggtgaaaa gattacggac attgaaacct tccacccaga ccgcatgtct
     5281 agccgtatcc ttggtatggg ggatatgctc actttgattg agaaagcttc tcaggaatac
     5341 gatgaacaaa aagcccttga aatggctgag aagatgcgcg aaaacacctt tgattttaat
     5401 gatttcatcg atcaattaga tcaggtgcaa aatatggggc cgatggaaga cttgctcaag
     5461 atgattccag gtatggccaa caatccagcc cttcaaaaca tgaaggtgga tgaacgccag
     5521 attgctcgta aacgtgccat tgtgtcttcg atgacacctg aagagcgtga aaacccagat
     5581 ttgttaaatc caagccgtcg ccgtcgtatt gctgctggtt ctggaaatac attcgtcgaa
     5641 gtcaataaat tcatcaagga ctttaaccag gctaaacagc tcatgcaggg tgttatgtct
     5701 ggggatatga ataaaatgat gaagcaaatg gggattaatc caaataacct tcctaaaaat
     5761 atgccaaata tgggaggaat ggatatgtct gcccttgaag gaatgatggg acaaggcggt
     5821 atgcctgact tatcagctct cggaggagca ggaatgccag atatgagcca gatgtttggt
     5881 ggcggtttga aaggtaaaat tggtgaattt gccatgaaac agtccatgaa acgtatggct
     5941 aacaaaatga agaaagcgaa gaagaaacgc aagtaagaca agagattgat gcaaatctca
     6001 tttgatgaga aaataaagta aaaatttcta tgataaaacg tacagtatca aggttttaga
     6061 atatctgata ttatacgttt tttgatttta ataattttgt taagacactt ttattatagt
     6121 atacgaaaaa tccactcagc tgtctgagtg gattaggtgt atttagactc ttagtcttta
     6181 ttttcgtatg gcaagatcaa gttcaagatg attcctgtca tggctgaaag ggcagtacct
     6241 gaaagtgtaa ctggaccaag tttaaggata gctcctccaa gtccaagaac caacatagca
     6301 cttgcgatga tgaggtttcg catttgagcg aaatcaacac gttctttaat caagactttc
     6361 aaaccattgc tggcgataac cccatagaga aggattgaca taccaccaag tacagcgttt
     6421 ggaatagttg aaatcaaggc agtgaattta ccaaggaagc tgagggcaat cgcgatgaag
     6481 gcagcgttac ggataactga gacagaagcg atacgagtca taccgataac ccctgtattt
     6541 tctccgtaag ttgtattggc tggtccacca aggaaggcag aaacagaagt tgcgataccg
     6601 tcaccaataa gagtacggtg aagacctggt tcttttaaga attgacggcc acagatttga
     6661 cccaaaacag tatggtctcc gatatgttca gaaattgtta cgatagcgat tggcaagata
     6721 gcgatggctt ctggaccaaa gtaaagattg tactctttaa aggcaccact tgtgctaaat
     6781 ggcaagtaga aaccaggaat ttcaaaccag ttagcttcta ggacaggcgt aaagtcaacc
     6841 aaaccaagag ttagtgcgaa gaggtaacca ccgataatgg caaagaggaa tggaatgatt
     6901 cgtaggaagc cttttccttt tgtattgata aaggcagcaa ttaggaaagt aacaacggct
     6961 accagagcat ttttccaatt tccgtctgct acaagacctg cattggtaac agctgaacct
     7021 gcaagtccaa gaccgataac gatgatcata ggaccgataa tgattggtgg caagagttta
     7081 tcaatccatt ttgttcctac aaatcggatg ctggtagcaa caaggacata gaccaaacca
     7141 gtcaagataa cccctgtttg agcagcagat acatcccccc ccatttcttt catagccagt
     7201 gacatagctg tgataaaggc gaatgaagaa cctagataaa ctggaacttt aaaaccagta
     7261 gcaagcatgt agatgagtgt tccaacacct gaagcaaaaa gggcaacaga tacaggcatt
     7321 cccaaaatca atggtaccaa gatggtcgca ccaaacatgg cgaaaacgtg ttggaaacta
     7381 aggagaattc cttttccagc cgaaggacgt tggtcaacgt ctagtaacaa atcaacagtt
     7441 gattcttgtt tcatataaac ctcacttttg ggcatcaaaa aagagcccat tattttacag
     7501 caataggccc tcagagtaag acttctttaa aatttagatt ttaaagagtt ttaaatattt
     7561 ctgcgtcttc gtcacctcac gggatgacat taaaaacctt tgcttaggat agtatagcag
     7621 aaaaaaatga ttttgtaaat cattttttcc cgagcctaga aataaaagag cgaggctgat
     7681 tttgtaaaca tttgtttact aaaaaattta aagtgggcgt ttatttggca taccagcctt
     7741 acgtggatat ttatttggtg tttctttttt cttttctacc actgtgatat agcgcggatc
     7801 tctattcggt agggcgtagc tgagattgtc ttcgacctta ctaaaaagga gattgagggc
     7861 attcttagct tctaataatt cctcaggcgc attgctggcc ttgagtgcca atagttttcc
     7921 accaacctta aggtagggaa tggtcaattc agataggacc tgcatacggg caaccgcacg
     7981 agctgttaca aaatcatatt gagcacggaa gttcttgtct tgggcaaaat cttcggcacg
     8041 tccgtggtag aaatgaactc cgttcaaatc cagttcttga gccaagagtt gtaggaagtt
     8101 gatgcgctta ttgagtgaat caataatggt cacatctaac tccggataga gaattttcat
     8161 tggtagacta ggaaatcctg ccccagcccc gatatcaaga agtttgatag tttcattggg
     8221 aatcaaacct tgaagaatgg gtgcaatcga atcgtaaaaa tgtttgagat aaacttcttc
     8281 cttgtccgta atcgccgtca aattaatctt ctcattccac tcgaccaaga gctcaaaata
     8341 acgttcaaat tgttcttttt gctggtccga aagtggaaga ttctgctcgg caagcaagtt
     8401 gtaaaatgtt tttggtttca tagttatttc cttctttagt atcatcttat tttaccacaa
     8461 tcatagaaaa tttgatatac tggtactaat ctaaaagcag aaaggactta tattatgact
     8521 tggattattc ttggagttat cgctcttatt gttatttttg tgattgttag ctataacggt
     8581 ttggttaaaa atcgtatgca aaccaaggag gcttggagtc agattgatgt tcagttgaaa
     8641 cgtcgaaatg acctcttgcc gaacttgatt gagactgtaa aaggttatgc caaatatgaa
     8701 ggttctaccc ttgaaaaggt ggcagaacta cgtaaccaag tggcggcagc gacttcacca
     8761 gcagaagcta tgaaagccag tgatgccctc actcgtcagg tttcaggtat ttttgcagtt
     8821 gcagaaagct atccagattt gaaagctagt gctaactttg ttaaattgca agaggagttg
     8881 acaaacacag aaaataaaat ttcttactct cgtcaactct ataacagtgt tgtcagcaac
     8941 tacaatgtaa aattagaaac tttcccgagc aatattatcg ctggaatgtt tggatttaaa
     9001 gcggcagatt tccttcaaac acctgaagag gaaaagtcgg ttcctaaagt tgattttagc
     9061 ggtttaggtg actaagatgt tgtttgatca aattgcaagc aataaacgaa aaacctggat
     9121 tttgttgctg gtatttttcc tactcttagc tcttgttggt tatgcggttg gttatctctt
     9181 tataagatct ggacttggtg gtttggttat cgcactgatt atcggcttta tctacgcttt
     9241 gtctatgatt tttcaatcga cagagattgt catgtccatg aatggagcgc gtgaggtgga
     9301 tgagcaaacg gcaccagacc tctaccatgt agtggaagat atggctctgg tcgcccagat
     9361 tcctatgccc cgtgttttca tcattgatga tccagcctta aatgcctttg cgacaggttc
     9421 taatcctcaa aatgcggctg ttgctgcgac ttcaggtcta ctagctatca tgaatcgtga
     9481 agaactagaa gctgttatgg gacatgaagt cagtcatatt cgtaattatg atatccgtat
     9541 ttcgactatt gcagttgccc ttgctagtgc tatcaccatg ctttctagta tggcaggtcg
     9601 tatgatgtgg tggggtggag caggtcgcag acgaagtgat gatgaccgag atggaaatgg
     9661 tcttgaaatc attatgctag tggtttccct actagctatt gtactggcac ctctcgctgc
     9721 aaccttggtt cagctcgcta tttctcgtca gagggaattt ctggcagatg catctagtgt
     9781 cgagctgact cgcaatcccc agggaatgat taatgcccta gataagttgg acaatagcaa
     9841 acctatgagt cgccacgtcg atgatgctag cagtgctctt tatatcaatg atcccaagaa
     9901 aggtgggggg ttccaaaaac tcttttatac ccacccacct atctcagaac ggattgaacg
     9961 tttaaaacag atgtaaaatg aaggctggaa aaaagtcttt aaaatctgaa aaacgcataa
    10021 tatcaggtgt gaaaacttga tattatgcgt tttactatgg gaagatttac ttctttttct
    10081 cctaaaattg tgtttttgcc ccacctatct gctatgttgc aaatttataa atcttctaaa
    10141 ttaactagct tcaaaccgtg ttctgtcatg cgatagatga tcgagcagat ttcttttaag
    10201 aaacgacggt catgcgaaac agtgatgaga ccgcctggat aggttgcaaa gagttttctg
    10261 atttggggtt gagaagtggg agaaaagttt cgtgtgggtt catccagcag gagaaagttt
    10321 ggtttgcgca ggactaaatc caaaagcagg agttttccct gttgtccgcc agataaggag
    10381 cgaatttgat gctgcatttc tggataactg aaattgagac tggctaggtg agattggatt
    10441 ttctgaagtt cctctttttc cccagttttg ctgatataag ctattggtga taaatccaat
    10501 tgcagttttt tgtggtaatc ttgtggcata aaaccaaggg aaatctctct tttatcattc
    10561 agaagttgct ttaatttggc taacagagtt gatttcccaa caccatttgg cccgataata
    10621 ccgatttttt cttgcccacg gacagttagt tgtagttttt gaaccaaaac tcggtcgtca
    10681 atggacaaat tttctttttc cagttggact aagactttag aagctggtaa tggttggatg
    10741 tctgaaaaga aaagttggat ttgttcctct tcaagtggct tttgagtcat ggactgagct
    10801 gtcttttcgt agcgtttttc ttgtgagagg acagttttca tctttttagc caataggcga
    10861 ccggcagtac tatctttggt agctcgaagc gcagtttcta cattttgctt aactctccga
    10921 tgtttttcca tggttttatc gtaggctctt tggttgttag cagcttgctg actttgtttg
    10981 gcaaaattag cctttctctg ctcactatag ctatcatagt ctaaatgctc tactagcgtt
    11041 tccgcttctt tacggtgttt gaccagtcgc aagtgaacaa tagtgtctgc tgtttcagaa
    11101 agaaagtctt catcatggga aatgaaaata acggtttgcc tggtcttttg aatctggcct
    11161 tttagccaat caactgtctc aaggtctagg tcatttgaag gttcatctaa aaatagaatc
    11221 tcaaagggtt tggctaactc atggataagc tgaattttca aagcttctcc ccctgataga
    11281 ttgccaatct tttggtcact tgcgaaacga ttgctatcaa aatgcaattc ctccgccaaa
    11341 cgatagagga tactgtagtc taaatcaata gaatctaaaa agaagtagtc gtgtaaagtt
    11401 ttctttttca gctcctcggg aagtttttga ggaatgtagg ccagtgactg atagtcagat
    11461 tggatgtttc ccttgatagt gaaatcagac aaagcttccc ccattaaaat tttaagtaag
    11521 gttgatttgc catttccttc ttcaccaata atagcaacct tttccccgtc ttggatggtc
    11581 atgcttaggt cagatacaag atctcgtaaa tctttgtttt gtgtgatggt tagatgattg
    11641 atttttatca tatgatttcc ctttctagaa tgttcatagt gcataacaaa aagctctact
    11701 ttacctagta gagcccaaag tctatgtcaa aaaaactcta ttaacatgcc agaaaaagag
    11761 cataaaagag cacacaaaaa gagacaaaaa caagatctac taaataaagg ttctttattt
    11821 gatagactta gttgttcatg tctcccttac ctccgagtat tagtatcttt atattatacc
    11881 tttaaggaaa ttttgtcaac agaaaactgg aaattctatg ctctaaaatc caaaaacagg
    11941 tccatagaga cttagtacgt gtttgacatg ctcgtaatgg aatttatcat agtttcgcca
    12001 agcagtgcgt gcttgatcgt ttagttttag gctacccagt ccaatcagaa gactggtggg
    12061 ttggtaaaat ttctcaagat caattaagat actgttgttc aacttttccg tttttttgag
    12121 ctcttgcata gtagtgttta gcagctcttg tagtcgaata tcatctgccg taccctgttt
    12181 acagttttgg tagcttttat ttaacttgga taggagttga atgagtttct tgtcttccat
    12241 gtgagcatcc tccttgatct gatgtactct ttccctatag tatagcacta aaaaacaaaa
    12301 ctgtcatagt aaatatgtta aaattctgaa ttttaattac aaagtttggt gtgctgattt
    12361 gtagcctttt catggtataa tcaagagagt aaatctttat ggaggaagta tgaaattaaa
    12421 tattcaagaa attcgtaagc agtctgaagg tttgaacttt gaacaaacgt tagatttagt
    12481 tgatgacctg cgtgcacgta atcaagaaat tttagatgta aaagatatcc ttgcagttgg
    12541 gaaagtacaa tatgaagacc gtatgtattt cttagattat caactatctt ataccattgt
    12601 tcttgcttcg agtcgcagta tggagccagt tgagttagtt gaatcttatc cagtcacgga
    12661 agttttcatg gaaggcgcaa ctaaccatct aaatcaagaa attttagatg atgacttggt
    12721 cttgcccatc gaaaatgagg cgcttgacct tgctgagagt gtatcagaca atatcttgct
    12781 aaacattcct atcaaggtct tgacggctga agaagaagct ggtcaaggat ttgtctcagg
    12841 aaatgactgg caaatcatga cagaggaaga ataccaagct caacaagcag taaagaaaga
    12901 agaaaacagt ccttttgctg gcttacaagg actatttgac ggagatgaat aatggtcttg
    12961 tcaaaaaaac gagcacgaaa ggtgctagaa gaaatcattg ccctcttccc agatgccaag
    13021 cctagtcttg attttaccaa tcattttgaa ctcctggttg cggtcatgtt atcagcccag
    13081 acgacagatg cagcggtaaa taaggccaca ccaggtctct ttgttgcctt tccaacaccc
    13141 caagctatgt ctgtagcgac agagagtgag attgcttcac atatttctcg cttgggattg
    13201 tatcggaata aagctaaatt ccttaaaaaa tgtgcccaac agttactaga cgattttgat
    13261 ggtcaagtcc ctcagacacg tgaagaattg gagagtttgg caggtgttgg tcgcaagaca
    13321 gccaatgttg tcatgagtgt aggatttggg attccagcct ttgcagttga tactcatgtg
    13381 gagcgtattt gcaaacacca cgatattgtc aaaaaatcag cgacgccact tgaggtggaa
    13441 aagcgggtca tggatatctt gccgcctgag cagtggttag ctgcccatca ggccatgatt
    13501 tattttggaa gagccatttg ccatccaaaa aatccagagt gtgaccagta cccacaatta
    13561 tatgatttta gcaatttgta agatgctaca ttgaaacttt ttgcttgatt ttaagcatgc
    13621 tttgtgctat agtaaatgat aactaaatat tcctttaaac ctgtcccgtg aggcaggcaa
    13681 ggagcgcgat aaagtagaag ggtgaagtct atactgtgtg cagtagggct cgcttggcta
    13741 taaatttcaa gtctccttgt ttaaggagac ttttcttttt ggaggtttgt catgaaaaca
    13801 aaagaagttg tagacgaatt gaccgtcaaa cgagcgatta cgcgtattac ttatgagatt
    13861 atcgaacgca acaaagattt gaataagatc gtcttggctg gtattaaaac tcgtggtgtc
    13921 tttattgccc accgaatcca agaacgtttg aagcagttag aaaatctttc agttcctgtt
    13981 gtggaattgg atactaaacc tttccgtgat gatgttaaaa gtggagaaga tacttctttg
    14041 gtttctgtcg atgtgacaga ccgcgaagtt atcttggtgg atgatgtgct ctatacaggt
    14101 cgtaccatcc gtgctgctat tgataatatt gtcggtcatg gtcgtcctgc gcgtgtgagt
    14161 ttagcagttc tagtcgatcg tggacataga gaattgccaa tccgtccaga ttacgttgga
    14221 aaaaatatcc caaccagtcg ttctgaagaa atcatcgtag agatgacaga acttgatgac
    14281 caagacagag ttctgattac tgaagaagct tagaaagtta aaggagtagc catgtcagaa
    14341 aatcaacaag cattgaacca tgtggtgtcc atggaagacc tcactgtcga tcaagtaatg
    14401 aaattgatca agcgaggaat tgagtttaaa aatggagccc agcttcccta tgaagaccat
    14461 ccgattgttt ccaatctctt ctttgaggat tctacacgga cacataagtc ctttgaagtc
    14521 gcagagatta aacttggatt ggaacgactt gactttgatg tgaagactag ttcggttaat
    14581 aagggtgaga cactttatga caccattttg actctgtctg ctttaggagt ggatgtctgt
    14641 gtgattcgcc atccagaggt cgactactat agagaattga ttgctagtcc aacgattacg
    14701 acttccatca tcaatggtgg agatggttcg ggccaacacc ctagccagag cttgcttgat
    14761 ttgatgacca tttatgagga atttggccac tttgagggtc ttaaagttgc tattgcaggt
    14821 gacttggacc actcacgcgt tgccaaatcc aatatgcaga ttttgaaacg cttgggatct
    14881 gaactctttt tcgctggacc tgaggaatgg agaagtcaag agtttgcaga ctatggacag
    14941 tttgtaacca ttgatgaaat cattgatcag gttgatgtca tgatgtttct ccgtgtgcaa
    15001 cacgaacgcc atgatagtgg agctgtattt tcaaaagaag actaccatgc ccaacatggc
    15061 ttgactcaag aacgttacga tcgtttgaaa gaaacagcaa tcctcatgca cccagctcca
    15121 atcaatcgtg atgtagaaat agcagaccac ttggttgaag caccaaaatc acggattgtc
    15181 caacaaatga ccaatggtgt ctttgttcga atggcaatct tagaatccgt actagcgagt
    15241 agaaacgcca actaaaacac aagacgttaa aagacgccag tgagcgtcca cgagaggtga
    15301 aaatatgaca aaaagaattc tagtattaga agatggcaca gtttttgaag gcaaggcctt
    15361 cggagcagat attgatgtaa caggcgaaat cgtctttaat acagggatga ccggctacca
    15421 agaatccatt acagaccagt cttataatgg acaaatcttg acctttactt atcctttggt
    15481 aggaaattat ggtattaatc gtgatgatta tgaatccatt attccaactt gtaagggagt
    15541 cgttgttttt gaagaagcgc gtagagctag caactggcgc aaccaaatga ccttggatga
    15601 atttttgaaa gccaagaaaa ttccagggat ttcaggaatt gatacgcgtg ctcttaccaa
    15661 gattatccgt aagcatggta ctatgcgtgc aaccttgacc catgttgggg acagtatgga
    15721 ccatgtgacg gaccagctcc aagcaacagt tttaccgaca gacaatatca aacaggtttc
    15781 tactaaaacg tcttatccag ctccaggagt tggtttgagc gtggtgctag tggactttgg
    15841 tctcaagcac tcaatcctac gtgaactttc taaacgcaac tgtaacgtga cagttgttcc
    15901 ttattcgaca acggctgaag aaattctcca tctcaatcct gacggagtta tgttgtcaaa
    15961 tggtccaggt aacccagaag acgttccaca agcactcgac atgattcgcg gtgtacaagg
    16021 aaaaattcca atctttggta tttgtatggg acaccaactc tttgcaatgg caaacggggc
    16081 taagacctat aagatgaagt ttggccaccg tggattcaac catgcggtac gtgaaatcgc
    16141 aacaggacga gtagacttca ccagccagaa ccatggttat gcagtcagcc gcgaggattt
    16201 gccagagcac ttgattatta cccacgaaga aatcaatgac aagtcagtgg aaggtgtgcg
    16261 ccacagatac caacctgctt tctctgttca ataccaccca gatgcagctc ctgggccaca
    16321 cgacgctagc tacctatttg acgagtttat cgagatgatg gaagttttta aacaatcaaa
    16381 ctaagaacga gtaaaagctc gtcggagaat ttatgtaact gaacacggac ggaaagctca
    16441 gaatgtagag aaaccaactt ggattgtcaa tccttccttg atttcctaaa attcaatcgc
    16501 tttctattcg tcctttgtat cttatttaat gtcgccctga gaggcgacga atagaaagga
    16561 gaagggagct ccgtatttgc tgaactgaat acgggctacg gacggtgcta aaaagatagt
    16621 tattcctaga actgacagtt cttcgtcata actcctattt tagctttgtc cgcttgacac
    16681 ccttaatatc ttatatatgc ctaaacgtac tgatattcaa aaaattatgg tgattggttc
    16741 tggtccgatt attattggtc aggctgctga gtttgactac gctgggactc aggcttgctt
    16801 gtcgttgaaa gaggaaggtt atgaggttgt tttggttaac tcaaatcctg caaccatcat
    16861 gacggacaag gaaattgctg acaaggttta cattgaaccg attacacttg agtttgtgac
    16921 acgtattctt cgtaaggaag gtccagatgc cttgctacca acactcggtg gtcagacagg
    16981 tctcaacatg gccatggaat tatctaaaaa tggtatccta gacgagcttg gcgttgaact
    17041 tctgggtacc aaattatctg ccattgacca agcggaggac cgtgatctct ttaaacaatt
    17101 gatggaagag cttgaacaac ccattccaga atctgaaatt gttaacacag tagaagaagc
    17161 agttgccttt gcagcgacaa ttggctaccc agtcatcgtt cgtccagcct ttacccttgg
    17221 tggtactggt ggtggtatgt gtgccaacga gaaagaattg cgtgaaatca ctgaaaatgg
    17281 tttgaaattg tcacctgtta cccaatgttt gattgagcgt tcgattgccg gtttcaagga
    17341 aattgaatac gaagtgatgc gtgactcagc tgacaatgcc ttggttgttt gtaacatgga
    17401 aaactttgac ccagttggga ttcacacagg ggattccatt gtatttgccc ctgcgcaaac
    17461 catgtcagac tatgaaaacc aaatgcttcg tgatgcgagc ttgagcatta ttcgtgccct
    17521 caagattgaa ggtggatgta atgttcagct agctcttgat cctaacagct tcaagtatta
    17581 tgttatcgaa gtaaaccctc gtgtatcacg ttcgtcagcc cttgcttcta aagcgacagg
    17641 atatccgatt gctaagttgg ctgccaagat tgcagtaggt ttgaccttgg atgaggttat
    17701 aaacccagtt acaggttcaa cctatgccat gtttgaacca gcccttgact acgtagttgc
    17761 taagattcca cgtttcccat ttgacaagtt tgaaaagggt gaacgccgtc tcggtacaca
    17821 aatgaaggcg actggagaag tcatggcaat cggtcgtaac atcgaggaat ctcttctcaa
    17881 ggcctgccgc tcccttgaaa ttggggtgca ccacaatgaa atacctgaac ttgcagcagt
    17941 ttctgatgat accttgattg aaaaggttgt caaagcccaa gatgaccgtc tcttctacgt
    18001 atcagaagcc attcgtcgtg gctacacacc tgaagaaatt gcagagctta caaaaattga
    18061 tatcttctat cttgataaac tcttgcatat ctttgaaatt gagcaagaat tgggtgctca
    18121 tccacaagat ctagaagttt tgaaaacagc caaacttaat ggtttttcag accgtaagat
    18181 tgctgaactc tggggaacga ctgatgataa agttcgccaa cttcgcttgg aaaacaagat
    18241 tgttccagtt tataagatgg tagacacttg tgcggcagag ttcgattccg aaacgccata
    18301 tttctattca acctatggtt gggaaaatga atctatcaaa tctgataaag aatctgtact
    18361 tgtcctaggt tcaggtccaa tccgtatcgg tcaaggggtt gagtttgact acgcaaccgt
    18421 tcactctgtt aaggctatcc aggcagctgg ttatgaagct atcatcatga actcaaaccc
    18481 agagaccgtt tcaacagact tctctgtatc agataagctt tactttgagc cattgacatt
    18541 cgaagatgtt atgaacgtca ttgacttgga acaaccaaag ggagttatcg ttcagttcgg
    18601 tggtcaaaca gccatcaacc ttgcagagcc attggcaaaa gcaggtgtga ccatccttgg
    18661 tacacaggtt gctgacctag accgtgccga agaccgtgac ctcttcgagc aagctctcaa
    18721 agaattggat attccacagc caccaggaca aacggctacc aatgaagaag aagcagctct
    18781 tgcagctcgt aagattggct tcccagttct tgtccgccca tcttatgtac ttggtggacg
    18841 tgccatggaa atcgttgaaa acgaagaaga ccttcgttct tacatgcgaa ctgctgttaa
    18901 ggctagtcca gaccatccag ttcttgtcga ctcttatatc gttgggcaag agtgcgaagt
    18961 tgatgccatt tcagatggta aaaatgtact cattcctggt atcatggagc atatcgaacg
    19021 tgctggtgtc cactcaggtg actcaatggc tgtttaccca ccacaaacct tgtcgcaaaa
    19081 ggttcaggag accatcgcag actacaccaa acgcttagca atcggtcttc actgccttgg
    19141 aatgatgaac atccagtttg ttatcaagga tgaaaaagtc tacgttattg aggtcaatcc
    19201 acgtgccagc cgtaccgttc cattcctatc taaggtaacc aatattccta tggctcaagt
    19261 agcgaccaag ctcattcttg gtcaaagttt atcagaactt ggctaccaaa atggacttta
    19321 ccctgaaagc acccgtgttc atatcaaggc acctgtcttc tcctttacca aactagctaa
    19381 ggtagacagc ttgctcggtc ctgaaatgaa gtcaacaggt gaagttatgg gttctgatgc
    19441 tactttggaa aaagctctct ataaagcctt tgaagcttct tatctacact tgccaacttt
    19501 tggtaatgtc gtctttacca tcgctgatga tgccaaagaa gaagccttga acttggctcg
    19561 tcgtttccaa aacattggtt atggaatcct tgcgacagaa gggacagcag ccttctttgc
    19621 tagtcatggc ttgcaagccc aacctgttgg taagattggt gatgacgata aggatatccc
    19681 aagttttgta cgcaaaggaa gaattcaagc tatcattaac acagtaggaa caaaacgaac
    19741 tgctgacgaa gatggtgagc aaattcgtcg ttcagccatt gaacacgggg tgcccctctt
    19801 cacagcgcta gatacagcta atgccatgct taaggtactt gaaagtcgta gctttgttac
    19861 agaagcgatt taaatagaaa aataagatat agcagactga atttagaaca gtacacaggg
    19921 atactaaaat atttctagaa attaatttga attttctaat tgatttgttc gcatcttatt
    19981 tcaatctact atagaaaaaa gtctttaaaa ttataaaacg catcatatca aggtttttca
    20041 aaaaccttga tatgatgcgt ttt
//
LOCUS       DAYYYC010000042        19507 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.042, whole genome shotgun sequence.
ACCESSION   DAYYYC010000042 DAYYYC010000000
VERSION     DAYYYC010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19507
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.042"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(<1..752)
                     /locus_tag="ACHBV5_001545"
     CDS             complement(<1..752)
                     /locus_tag="ACHBV5_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFM9967312.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNTPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQI
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHAQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(749..2074)
                     /gene="comD"
                     /locus_tag="ACHBV5_001546"
     CDS             complement(749..2074)
                     /gene="comD"
                     /locus_tag="ACHBV5_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HFM9967313.1"
                     /translation="MDFFLLVDLILYFLIISHSYRLICKDQINRKELFFFGAYTLLTE
                     IVLDFPFYLLYLDGLGIATFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYYGLFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRVYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKRKFE"
     gene            complement(2087..2227)
                     /gene="comC"
                     /locus_tag="ACHBV5_001547"
     CDS             complement(2087..2227)
                     /gene="comC"
                     /locus_tag="ACHBV5_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HFM9967314.1"
                     /translation="MKNTVKLEQFVALKEKDLQNIQGGEMRKMNEKSFNIFNFFNFFR
                     RR"
     gene            complement(2392..2465)
                     /locus_tag="ACHBV5_001548"
     tRNA            complement(2392..2465)
                     /locus_tag="ACHBV5_001548"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2429..2431),aa:Arg,seq:tct)
     gene            complement(2509..2988)
                     /gene="rlmH"
                     /locus_tag="ACHBV5_001549"
     CDS             complement(2509..2988)
                     /gene="rlmH"
                     /locus_tag="ACHBV5_001549"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFM9967315.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            3171..4352
                     /locus_tag="ACHBV5_001550"
     CDS             3171..4352
                     /locus_tag="ACHBV5_001550"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HFM9967316.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            4410..5168
                     /locus_tag="ACHBV5_001551"
     CDS             4410..5168
                     /locus_tag="ACHBV5_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFM9967317.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNYFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIIYFSNQEEYSRIINSLK"
     gene            5381..6742
                     /gene="dnaA"
                     /locus_tag="ACHBV5_001552"
     CDS             5381..6742
                     /gene="dnaA"
                     /locus_tag="ACHBV5_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFM9967318.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            6901..8037
                     /gene="dnaN"
                     /locus_tag="ACHBV5_001553"
     CDS             6901..8037
                     /gene="dnaN"
                     /locus_tag="ACHBV5_001553"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFM9967319.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTIKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            8102..8296
                     /locus_tag="ACHBV5_001554"
     CDS             8102..8296
                     /locus_tag="ACHBV5_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HFM9967320.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            8380..9495
                     /gene="ychF"
                     /locus_tag="ACHBV5_001555"
     CDS             8380..9495
                     /gene="ychF"
                     /locus_tag="ACHBV5_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFM9967321.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLIESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYESEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            9566..10135
                     /gene="pth"
                     /locus_tag="ACHBV5_001556"
     CDS             9566..10135
                     /gene="pth"
                     /locus_tag="ACHBV5_001556"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFM9967322.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     KADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            10136..13645
                     /gene="mfd"
                     /locus_tag="ACHBV5_001557"
     CDS             10136..13645
                     /gene="mfd"
                     /locus_tag="ACHBV5_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFM9967323.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKELMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            13703..13969
                     /locus_tag="ACHBV5_001558"
     CDS             13703..13969
                     /locus_tag="ACHBV5_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFM9967324.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            13962..14330
                     /locus_tag="ACHBV5_001559"
     CDS             13962..14330
                     /locus_tag="ACHBV5_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFM9967325.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGVVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            14335..14457
                     /locus_tag="ACHBV5_001560"
     CDS             14335..14457
                     /locus_tag="ACHBV5_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HFM9967326.1"
                     /translation="MENLLDVIEQFLSLSDEKLEELADKNQLLRLQEEKERKNA"
     gene            14450..15718
                     /locus_tag="ACHBV5_001561"
     CDS             14450..15718
                     /locus_tag="ACHBV5_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFM9967327.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKISFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            15715..16992
                     /gene="tilS"
                     /locus_tag="ACHBV5_001562"
     CDS             15715..16992
                     /gene="tilS"
                     /locus_tag="ACHBV5_001562"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFM9967328.1"
                     /translation="MREQDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNIDVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            16996..17538
                     /gene="hpt"
                     /locus_tag="ACHBV5_001563"
     CDS             16996..17538
                     /gene="hpt"
                     /locus_tag="ACHBV5_001563"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFM9967329.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            17554..>19507
                     /gene="ftsH"
                     /locus_tag="ACHBV5_001564"
     CDS             17554..>19507
                     /gene="ftsH"
                     /locus_tag="ACHBV5_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFM9967330.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
BASE COUNT         6738 a         3129 c         3650 g         5990 t
ORIGIN      
        1 cacttttgag attttttctc taaaatatct tttaattttc taatttttaa tcttgaaata
       61 ggacaacgat ggtcttcata gaaaacaatt tctaagtttt ttcgatcaat ttctctgata
      121 ttgcctatat ttaccaaaaa tgacttgtga ggagaataaa atcgctgagc atgtttgtcc
      181 ttttcctgaa tatctgtcat ggtaccataa aactcttttg caaaattctt accaataatg
      241 cgcaatttat gagagactcc tgtcgtttca atatacaaaa tatcatggta aggaattttt
      301 aaatcatttc ccttgtaatt gtagtcgaaa taatctacaa catcttcatt ttcaagtaac
      361 atactcttcg tgtagaagat attttgctca attcgcttct taaacatctc atcgttgata
      421 tccttatcaa caaaatctag ggctgatatc tggtatttat aggtcagagt cgcaaactct
      481 gatcgactgg tgataaagac gataatagcg taaggattgt aatgacgaat gagttgagca
      541 acttcaaatc cctttttctc aattccatga atatcgatat ctaggaaata aagttgattt
      601 acttcatcat tttcaatgta ttcttcaaat tcacggactt ttcccgttgt cttgtatgat
      661 attggagtat tcgattcttt cgaaatttca tccaatattc tctctagtct cacttgatgt
      721 tcaataacat cttctaaaat taaaactttc attcaaattt cctcttaaat ctaatgattt
      781 gtctaaatgt actgccttcc atctctgttt ctaaaataat gttgttgtac ttatctagta
      841 gttctttcac attatttaat ccgactccgc gatttcttcc cttagtggag aatcctaagg
      901 caaatagatc tcctgaagga gtcatcgtca ttttacatga attctgaatc acaataactg
      961 tttcagtttc catcttaata actgctactt ccatctgctt tttatagcta tcagccgatc
     1021 cttcgacagc attgttcaat aaaacgctca tgatacgcac taaatccaat agttcaattg
     1081 gaagcttggt aatcgtatct tttacttcca gtgtaaactc tacaccatta tttcgagcat
     1141 agacaattga ctgagcaacc aaacttcgta aagctgaatc ttctatgttg ttcaaatcaa
     1201 agtaagtgta cttatctgaa cgtagtttat gatttgcttt gaccaaaact tcattgtaaa
     1261 ctctgtcaat ttcctgtaaa ttaccactgt caattgccat ctgcatgctg acaagcattc
     1321 cagcataatc atgtcgaaaa ccacggattt cattatacag accgacaatt tcatctgtgt
     1381 aattctgtaa atgtttctgt tcaaatttct tctgcttcaa agcaatctct ttctccattt
     1441 gaactttatg agaattcatt gcaaagaagg tcaaaaggag agagataaag acaatagatg
     1501 acaaaatact tccaaaacta ttcaaatgtt taatcgtact taccatatct gaaacgaaag
     1561 atacaatatg tagcaatagt aaagcaaaaa atactttttt caagaaagga taaaggtagt
     1621 ccttgtcaaa ataggctagt tccaaatgga aataataaat gatttttaat gtaacaaaat
     1681 aggtcaacac cgtcacaacg aaaaagaata ggccataata ctgtaaaaca aaattgtctc
     1741 ctgttataga agagaaagtt acggacagaa agttatgagt gctctcatat aaaagagata
     1801 gtagtaaact tagaaatagt cctctatccc tctcatactg tttcatccat cgaaaatagg
     1861 aatataggcc caaaggaaat aaaaatgttg caatccctaa cccatctaaa tatagaagat
     1921 agaagggaaa atcaagtact atttctgtta gtaatgtata agcaccaaaa aagaataatt
     1981 cttttctatt tatttgatct ttacaaatta aacggtaact atgactaata attaaaaaat
     2041 ataatatcaa atctactaat aagaaaaaat ccattctgct actcctttat cttcttctaa
     2101 agaaattaaa gaaattaaag atattaaagg acttttcatt cattttcctc atctccccac
     2161 cttgaatatt ttgcaagtct ttttccttca aagctacaaa ctgttccaat ttaactgtgt
     2221 ttttcataat aaaatctcct aaaatgtttt ttcttgtaag ctaacttaca aaaaccatta
     2281 tacaaaatgg aatttcgttt tagataaaat tctctcaact gtcatttttt tctcccaaag
     2341 tgtacttttt taagaaaaaa gccgggaaaa ttcccagctt tgctattata ttgatcccag
     2401 caggattcga acctgcgacc gttcgcttag aaggcgaatg ctctatccag ctgagctatg
     2461 agacctaaca caattattct accaaaaatt caattaaaag tcaattttct atttatggta
     2521 ggggaatccc tgctgaatcg taaaagcgcg atagatttgt tcaacaagaa ctagtctcat
     2581 taactgatga ggcaaggtta ggcgaccaaa actgacagaa agattggctc tattttttac
     2641 agatgatgat aatcctaaac ttcccccaat aataaaagta agagtagaaa atccttttat
     2701 agaagtttct tctaactgct tactaaattc ttctgagaag aaagttttcc cttcaatggc
     2761 taacacaata acgaaatcac ggtcagcaat ttttgataaa attctctgac cttctatttc
     2821 taaaatcttt tgattttctg attcactggc cttatctggt gttttttcat ctgataactc
     2881 aatcatttca aacttagcaa atctagaaat tcgttttgaa tactctgcga taccatcttt
     2941 taaatacttt tctttcagtt tcccaactgt tacaacttta attttcatga ctctattcta
     3001 acatattctc tattttttca catcttattc acaaaataaa aaatagattt caattaagaa
     3061 aatcacagtt tcaaaagagt tatccacagt ttgtgtaaaa cttttgtgtt taagttataa
     3121 ttaagctagt cagtttatac tttcagtaat tcaaacatat ggaggcaaat atgaaacatc
     3181 taaaaacatt ttacaaaaaa tggtttcaat tattagtcgt tatcgtcatt agctttttta
     3241 gtggagcctt gggtagtttt tcaataactc aactaactca aaaaagtagt gtaaacaact
     3301 ctaacaacaa tagtactatt acacaaactg cctataagaa cgaaaattca acaacacagg
     3361 ctgttaacaa agtaaaagat gctgttgttt ctgttattac ttattcggca aacagacaaa
     3421 atagcgtatt tggcaatgat gatactgaca cagattctca gcgaatctct agtgaaggat
     3481 ctggagttat ttataaaaag aatgataaag aagcttacat cgtcaccaac aatcacgtta
     3541 taaatggcgc cagcaaagta gatattcgat tgtcagatgg gactaaagta cctggagaaa
     3601 ttgtcggagc tgacactttc tctgatattg ctgtcgtcaa aatctcttca gaaaaagtga
     3661 caacagtagc tgagtttggt gattctagta agttaactgt aggagaaact gctattgcca
     3721 tcggtagccc gttaggttct gaatatgcaa atactgtcac tcaaggtatc gtatccagtc
     3781 tcaatagaaa tgtatcctta agatcggaag atggacaagc tatttctaca aaagccatcc
     3841 aaactgatac tgctattaac ccaggtaact ctggcggccc actgatcaat attcaagggc
     3901 aggttatcgg aattacctca agtaaaattg ctacaaatgg aggaacatct gtagaaggtc
     3961 ttggtttcgc aattcctgca aatgatgcta tcaatattat tgaacagtta gaaaaaaacg
     4021 gaaaagtgac gcgtccagct ttgggaatcc agatggttaa tttatctaat gtgagtacaa
     4081 gcgacatcag aagactcaat attccaagta atgttacatc tggtgtagtt gttcgttcgg
     4141 tacaaagtaa tatgcctgcc aatggtcacc ttgaaaaata cgatgtaatt acaaaagtag
     4201 atgacaaaga gattgcttca tcaacagact tacaaagtgc tctttacaac cattctatcg
     4261 gagacaccat taagataacc tactatcgta acgggaaaga agaaactacc tctatcaaac
     4321 ttaacaagag ttcaggtgat ttagaatctt aattgacatc tatgtaaaga aagctttaca
     4381 taagagaaaa gatgtgttag tgtagaatca tggaaaaatt tgaaatgatt tctatcacag
     4441 atatacaaaa aaatccctat caaccccgaa aagaatttga tagagaaaag ctagatgaac
     4501 tagcacagtc tatcaaagaa aatggggtca ttcaaccgat tattgttcgt caatctcctg
     4561 ttattggtta tgaaatcctt gcaggagaga gacgctatcg ggcttcactt ttagctggtc
     4621 tacggtctat cccagctgtt gttaaacaga tttcagacca agagatgatg gtccagtcca
     4681 ttattgaaaa tttacagaga gaaaatttaa acccaataga agaagcacgc gcctatgaat
     4741 ctctcgtaga gaaaggattc acccatgctg aaattgcaga taagatgggc aagtctcgtc
     4801 catatatcag caactccatt cgtttacttt ccttgccaga acagattctc tcagaagtag
     4861 aaaatggcaa actatcacaa gcccatgcgc gttccctagt tgggttaaat aaggaacaac
     4921 aagactattt ctttcaacgg attatagaag aagatatttc tgtaaggaag ttagaagctc
     4981 ttctgacaga gaaaaaacaa aagaaacagc aaaaaactaa ttatttcata caaaatgaag
     5041 aaaaacagtt aagaaaacta ctcggattag atgtagaaat taaactatct aaaaaagaca
     5101 gtggaaaaat cattatttat ttttcaaatc aagaagaata tagtagaatt atcaacagcc
     5161 tgaaataagg ctgttctttt atttttttat ctcacaaggt tatccactat gtttttcgat
     5221 aaaaagctta ataaatcaat aatttcttct tttatcccca acctgtggat aaagtttagt
     5281 aacattgtgg attatttttc acagcttgtg gaaaattctt gctatctatg gtaaaatatc
     5341 tctagtatta aacttttaaa tagtaaagga ggaaaaagga ttgaaagaaa aacaattttg
     5401 gaatcgtata ttagaatttg cacaagaaag actgactcga tccatgtatg atttctatgc
     5461 tattcaagct gaactcatca aggtagagga aaatgttgcc actatatttc tacctcgctc
     5521 tgaaatggaa atggtctggg aaaaacaact aaaagatatt attgtagtag ctggttttga
     5581 aatttatgac gctgaaataa ctccccacta tattttcacc aaacctcaag atacgactag
     5641 ctcacaagtt gaagaagcta caaatttaac tctttatgac tatagtccaa agttagtatc
     5701 tattccttat tcagatacgg gattaaaaga aaagtatacc tttgataact ttattcaagg
     5761 ggatggaaat gtttgggctg tgtcagccgc tttagctgtc tctgaagatt tggctctgac
     5821 ctataaccct ctttttatct atggaggacc aggccttggt aagactcact tattaaacgc
     5881 tattggaaat gaaattctaa aaaatattcc taatgcgcgt gttaaatata tccctgccga
     5941 aagctttatt aatgactttc ttgatcacct aagacttggg gaaatggaaa agtttaaaaa
     6001 gacctatcgt agtcttgatc ttttgttaat cgatgatatc cagtcactca gcggaaaaaa
     6061 agtcgcaact caggaagaat ttttcaatac ctttaacgcc cttcatgaca agcaaaaaca
     6121 gattgtccta acgagtgatc gtagtccaaa acatctagaa gggctcgagg agaggcttgt
     6181 cacgcgtttt agttggggat tgacacaaac tatcacaccc cctgactttg aaacacgtat
     6241 tgccatttta caaagtaaaa cggaacattt aggctacaat ttccaaagtg atactctaga
     6301 atacctagct gggcaatttg attcaaatgt tcgagatctt gagggagcca tcaacgacat
     6361 cactttaatt gccagagtaa aaaaaatcaa ggatatcact attgatattg ctgcagaagc
     6421 cattagagcc cgcaaacaag atgttagcca aatgctcgtc atcccaattg ataaaatcca
     6481 aactgaagtt ggtaactttt atggtgttag tatcaaagaa atgaagggaa gtagacgcct
     6541 tcaaaatatt gttttggccc gtcaagtagc catgtattta tctagagaac taacagataa
     6601 tagtcttcca aaaattggga aggaatttgg gggaaaagat cataccacag tcattcatgc
     6661 ccatgccaaa ataaaatctt tgattgatca agacgataat ttacgtttag aaattgaatc
     6721 aatcaaaaag aaaatcaaat aatttgtgga taacttttag ttttttatct tttttatcca
     6781 cattttttaa acaagctaaa aaacttgata ggacttgttt aaaggctgtt ttccacagat
     6841 ttcacagact ctattattac tattatcttt ctaatactaa aaataaataa aggagaatcc
     6901 atgattcatt tttcaattaa taaaaattta tttctacaag cattaaatac tactaagaga
     6961 gctattagtt ctaaaaatgc cattcctatt ttatcaacaa taaaaattga cgtgaccaat
     7021 gaaggtatta ctttaattgg ttcaaatggt caaatttcaa ttgaaaattt tatttctcaa
     7081 aaaaatgaag atgctggttt gttaattact tctttaggtt cgatccttct tgaagcttct
     7141 ttctttatca atgtagtatc tagtttacct gatgtaactc ttgattttaa agaaattgaa
     7201 caaaatcaaa ttgttttaac cagtggcaaa tcagaaatta ccctaaaagg aaaagatagc
     7261 gaacaatatc cacgaatcca agaaatttca gcaagcactc ctttaatact tgaaacaaaa
     7321 ttactcaaga aaattattaa tgaaacagcc tttgctgcaa gtacacaaga gagtcgtccg
     7381 attttaacag gtgtccactt cgtattgagt caacacaaag agttaaaaac agttgcaaca
     7441 gactctcatc gcctaagcca gaaaaaattg actcttgaaa aaaatagtga tgattttgat
     7501 gtcgtaattc ctagccgttc tctacgcgaa ttttcagcgg tatttacaga tgatatcgaa
     7561 actgtagaga ttttctttgc caataaccaa atcctcttta gaagcgaaaa tattagcttc
     7621 tatactcgtc tcctagaagg aaactatcct gatacagatc gcttgattcc aacagacttt
     7681 aacactacta ttacttttaa tgtggtaaac ttacgccagt caatggagcg tgcccgtctt
     7741 ttatcaagtg cgactcaaaa tggtactgtg aaacttgaaa ttaaggatgg ggttgttagc
     7801 gcccatgttc actctccaga agttggtaaa gtaaacgaag aaatcgatac tgatcaggtt
     7861 actggtgaag atttgaccat tagtttcaac ccaacttact tgattgattc tcttaaagct
     7921 ttaaatagcg aaaaggtgac cattagcttt atctcagctg ttcgtccatt tactcttgtg
     7981 ccagcagata ctgacgaaga cttcatgcag ctcattacac cagttcgtac aaattaagtg
     8041 aaagaggttg agcctggctc gcctctttta tgatataatc gaaaaagaaa aggagagtag
     8101 tatgtatcaa gttggaaatt ttgttgagat gaaaaaatca cacgcttgta caatcaagtc
     8161 gactggtaaa aaggctaatc gttgggaaat tacacgtgta ggagcagata tcaaaataaa
     8221 atgcagtaat tgtgagcatg ttgtcatgat ggggcgatat gattttgagc gaaaaatgaa
     8281 taaaattatt gactgagaac ccttagttag agggttagca ctttatccct ttttgtgtta
     8341 taatattagg gattgaaatg aaaacggaga atgagaaata tggctttgac agcaggtatc
     8401 gttggtttgc caaacgttgg taaatcaaca ctatttaatg caattacaaa agcaggagca
     8461 gaggcagcaa actacccatt tgcgactatt gatccaaatg ttggaatggt ggaagttcca
     8521 gatgaacgcc tacaaaaact aactgaaatg ataactccta aaaagacagt tcccacaaca
     8581 tttgaattta cggatattgc agggattgta aaaggagctt caaaaggaga agggctaggg
     8641 aataaattct tggccaatat tcgtgaagta gatgcgattg ttcacgtagt tcgtgctttt
     8701 gatgatgaaa atgtgatgcg cgagcaagga cgtgaagacg cctttgtgga tccacttgca
     8761 gatattgaca ccattaacct agaattgatt cttgcagact tagaatcagt caataaacga
     8821 tatgcgcgtg tagaaaagat ggcacgtacg caaaaagata aagaatcagt agcagaattc
     8881 aatgttcttc aaaagattaa accagtccta gaagacggga aatcagctcg taccattgaa
     8941 tttacagatg aggaacaaaa ggttgtcaaa ggtcttttcc ttttgacgac taaaccagtt
     9001 ctttatgtag ctaatgtgga cgaggatgtg gtttcagaac ctgactctat cgactatgtc
     9061 aaacaaattc gtgaatttgc agcgacagaa aatgctgaag tagtcgttat ttctgcgcgt
     9121 gctgaggaag aaatttctga attggatgat gaagataaaa aagagtttct tgaagccatt
     9181 ggtttgatag aatcaggtgt agataagttg acgcgtgcag cttaccactt gcttggattg
     9241 ggaacttact tcacagctgg tgaaaaagaa gttcgcgctt ggactttcaa acgtggtatg
     9301 aaggctcctc aagcagctgg tattatccac tcagactttg aaaaaggctt tattcgtgca
     9361 gtaaccatgt catatgagga tctagtgaaa tacgaatctg aaaaggccgt aaaagaagct
     9421 ggacgcttgc gtgaagaagg aaaagaatat atcgttcaag atggcgatat catggaattc
     9481 cgctttaatg tctaaaaatt aataaatggt gtcaattagg ttggaaaaaa attccaaccc
     9541 ttttggcttt tgaaaggaaa aataaatgac caaattactt gtaggcttgg gaaatccagg
     9601 ggataaatat tttgaaacaa aacacaatgt tggttttatg ttgattgatc aactagcgaa
     9661 gaaacagaat gtcactttta cacacgataa gatatttaaa gctgacctag catccttttt
     9721 cctaaatgga gaaaaaattt atctggttaa accaacgacc tttatgaatg aaagtggaaa
     9781 agcagttcat gctttattaa cttactatgg tttggatatt gacgatttac ttatcattta
     9841 cgatgatctt gacatggaag ttgggaaaat tcgtttaaga gcaaaaggct cagcaggtgg
     9901 tcataatggt atcaagtcta ttattcaaca tataggaact caggtcttta accgtgttaa
     9961 gattggaatt ggaagaccta aaaatggtat gtcagttgtt catcatgttt tgagtaagtt
    10021 tgacagggat gattatatcg gtattttaca gtctgttgac aaagttgacg attctgtaaa
    10081 ctactattta caagagaaaa attttgagaa aacaatgcag aggtataacg gataaatggt
    10141 gaccttatta gatttattct cagaaaatga tcagattaaa aaatggcatc aaaatttaac
    10201 tgataagaaa agacaactaa tacttggttt atcaacatct actaaggctc ttgcaattgc
    10261 aagcagttta gaaaaagaag ataggattgt gttattgacg tcaacttatg gagaagcaga
    10321 aggacttgtt agtgatctta tatctatctt gggtgaggaa ctcgtctatc catttttggt
    10381 agatgatgct cctatggtgg agtttttgat gtcttcacag gaaaaaatta tttcacgggt
    10441 tgaagccttg cgttttttga ctgattcatc taagaaaggg attttagttt gtaatatcgc
    10501 agcaagtcga ttgattttac cgtctcccaa tgcattcaaa gatagtattg taaaaatctc
    10561 agttggtgaa gaatatgatc aacacgcgtt tatccatcag ttaaaggaaa atggctatcg
    10621 aaaagttact caagtacaaa ctcagggcga atttagtctt cgaggagata ttttagatat
    10681 ttttgaaata tcccagttag aaccttgtcg aattgagttt tttggtgatg aaattgatgg
    10741 tatcaggtca tttgaagtag aaacacaatt atcgaaagaa aataagacag aactcactat
    10801 ctttccagct agtgatatgc ttttgagaga aaaggattat caacgaggac agtcagcttt
    10861 agaaaaacaa atttcaaaaa ctttatcacc tattttgaaa tcatacctag aagaaattct
    10921 ttcaagtttt caccaaaaac aaagtcatgc agactctcgg aagtttttat ctttgtgcta
    10981 tgataagaca tggactgtct ttgattatat tgaaaaagat actccaatat tctttgatga
    11041 ttatcaaaaa ttgatgaatc agtatgaagt ctttgaaaga gacttagcgc agtactttac
    11101 agaagaatta cagaatagta aagcattttc tgatatgcag tatttttctg atattgaaca
    11161 aatctataaa aaacaaagtc cagtgacctt tttctctaat cttcaaaagg gtttaggaaa
    11221 tctcaaattt gacaaaattt atcaattcaa tcaatatcct atgcaggaat ttttcaatca
    11281 gttttctttt ctaaaagaag aaattgaacg atataaaaaa atggattaca ccattattct
    11341 gcagtctagc aattcaatgg gaagtaaaac attggaggat atgttagagg aatatcagat
    11401 taaattggat tctagagata agacaaatat ctgtaaagaa tctgtaaact taatagaggg
    11461 taatctcaga catggttttc attttgtaga tgaaaagatt ttattgataa ctgaacatga
    11521 gatttttcaa aagaaattaa agcgtcgttt tcgaagacaa catgtttcaa atgcagagag
    11581 attaaaagat tacaatgaac ttgaaaaagg ggactatgtt gtccatcata tccatgggat
    11641 tggtcaatat ctaggaattg aaaccattga aatcaaggga attcatcgcg attatgtcag
    11701 tgtccaatac caaaatggtg atcaaatttc tatccccgtg gaacagattc atctactgtc
    11761 caaatatatt tcaagtgatg gtaaagctcc aaaactcaat aaattaaatg acggtcattt
    11821 taaaaaggcc aagcaaaagg ttaagaacca ggtagaggat atagctgatg atttaatcaa
    11881 actctactct gaacgtagtc agttgaaggg ttttgctttc tcagctgatg atgatgatca
    11941 agatgccttt gatgatgctt tcccttatgt tgaaacggat gatcaacttc gtagtattga
    12001 ggaaatcaaa agggatatgc aggcttctca gccaatggat cgacttttag ttggggatgt
    12061 tggttttgga aagactgaag ttgctatgcg tgcagccttt aaagcagtca atgatcacaa
    12121 acaggttgtc attctagttc cgacgacggt tttagcgcaa cagcactata cgaattttaa
    12181 ggaacgattc caaaattttg cagttaatgt tgatgtgttg agtcgcttta gaagtaaaaa
    12241 agagcagact gcaacacttg aaaaattgaa aaacggtcaa gtcgatattt tgattggaac
    12301 acatcgtgtt ttgtcaaaag atgttgtgtt tgctgatttg ggcttgatga ttattgatga
    12361 ggaacagcga tttggtgtca agcataagga aactttgaaa gaactgaaga aacaagtgga
    12421 tgtcctaacc ttgaccgcta cgccaatccc tcgtaccctc catatgtcta tgctgggaat
    12481 cagagatttg tctgttattg aaactccgcc gactaatcgc tatcctgttc agacctatgt
    12541 tttggaaaag aatgatagtg tcattcgtga tgctgtcttg cgtgaaatgg agcgtggagg
    12601 tcaagtttac tatctttaca acaaagttga cacaattgtt cagaaggttt cagaattaca
    12661 ggagttgatt ccggaggctt cgattggata tgttcatggt cgaatgagtg aagtccagtt
    12721 ggaaaatact ctattagact ttattgaggg acaatacgat atcttggtga cgactactat
    12781 tattgagaca ggggtggaca ttccaaatgc taatacttta tttattgaaa atgcggacca
    12841 tatgggcttg tcaaccttat atcagttaag aggaagagtc ggtcgtagta atcgtattgc
    12901 ttatgcttat ctcatgtatc gtccagaaaa atcaatcagt gaagtctctg aaaagagatt
    12961 agaagcgatt aaaggattta cagaattggg ctctggcttt aagattgcaa tgcgagatct
    13021 ttcgattcgt ggagcaggaa atcttttagg aaaatcccag tctggtttca ttgattctgt
    13081 tggttttgaa ttgtattcgc agttattaga ggaagctatt gctaaacgaa acggtaatgc
    13141 taacgctaac acaagaacca aagggaatgc tgagttgatt ttgcaaattg atgcctatct
    13201 tcctgatact tatatttctg atcaacgaca taagattgaa atttacaaga aaattcgtca
    13261 aattgacaac cgtgtcaatt atgaagagtt acaagaggag ttgatagacc gttttggaga
    13321 atacccagat gtagtagcct atcttttaga gattggtttg gtcaaatcat acttggacaa
    13381 ggtctttgtt caacgtgtgg aaagaaaaga taataaaatt acaattcaat ttgaaaaagt
    13441 cactcaacga ctgtttttag ctcaagatta ttttaaagct ttatccgtaa cgaacttaaa
    13501 agcaggcatc gctgagaata aggaattaat ggagcttgta tttgatgttc aaaataagaa
    13561 agattatgaa attttagaag gtctgctgat ttttggagaa agtttattag agataaaaga
    13621 gtctaaggaa gaaaattcca tttgatattt ttcttctata aaatagataa aaatggtaca
    13681 ataataaatt gaggtaataa ggatgagatt agataaatat ttaaaagtat cgcgaattat
    13741 caagcgtcgt acagtcgcaa aggaagtagc agataaaggt agaatcaagg ttaatggaat
    13801 cttggccaaa agttcaacgg acttgaaagt taatgaccaa gttgaaattc gctttggcaa
    13861 taagttgctg cttgtaaaag tactagagat gaaagatagt acaaaaaaag aagatgcagc
    13921 aggaatgtat gaaattatca gtgaaacacg ggtagaagaa aatgtctaaa aatattgtac
    13981 aattgaataa ttcttttatt caaaatgaat accaacgtcg tcgctacctg atgaaagaac
    14041 gacaaaaacg gaatcgtttt atgggagtgg tattgatttt gattatgcta ttatttatct
    14101 tgccaacttt taatttagcg cagagttatc agcaattact ccaaagacgt cagcaattag
    14161 cagacttgca aactcagtat caaactttga gtgatgaaaa ggataaggag acagcatttg
    14221 ctaccaagtt gaaagatgaa gattatgctg ctaaatatac acgagcgaag tactattatt
    14281 ctaagtcgag ggaaaaagtt tatacgattc ctgacttgct tcaaaggtga taaaatggaa
    14341 aatttattag acgtaataga gcaatttttg agtttgtcag atgaaaagct ggaagaattg
    14401 gctgataaaa atcaattatt gcgtttacaa gaagaaaagg aaaggaagaa tgcgtaaatt
    14461 cttaattatt ttgttgctac caagtttttt gaccatttca aaagtcgtta gcacagaaaa
    14521 agaagtcgtc tatacttcga aagaaattta ttacctttca caatctgact ttggtattta
    14581 ttttagagaa aaattaagtt ctcccatggt ttatggagag gttcctgttt atgcgaatga
    14641 agatttagta gtggaatctg ggaaattgac tcccaaaata agttttcaaa taaccgagtg
    14701 gcgcttaaat aaacaaggaa ttccagtatt taagctatca aatcatcaat ttatagctgc
    14761 ggacaaacga tttttatatg atcaatcaga ggtaactcca acaataaaaa aagtatggtt
    14821 agaatctgac tttaaactgt acaatagtcc ttatgattta aaagaagtga aatcatcctt
    14881 atcagcttat tcgcaagtat caatcgacaa gaccatgttt gtagaaggaa gagaatttct
    14941 acatattgat caggctggat gggtagctaa agaatcaact tctgaagaag ataatcggat
    15001 gagtaaagtt caagaaatgt tatctgaaaa atatcagaaa gattctttct ctatttatgt
    15061 taagcaactg actactggaa aagaagctgg tatcaatcaa gatgaaaaga tgtatgcagc
    15121 cagcgttttg aaactctcct atctctatta tacgcaagaa aaaataaatg agggtcttta
    15181 tcagttagat acgactgtaa aatacgtatc tgcagtcaat gattttccag gttcttataa
    15241 accagaggga agtggtagtc ttcctaaaaa agaagataat aaagaatatt ctttaaagga
    15301 tttaattacg aaagtatcaa aagaatctga taatgtagct cataatctat tgggatatta
    15361 catttcaaac caatctgatg ccacattcaa atccaaaatg tctgccatta tgggagatga
    15421 ttgggatcca aaagaaaaat tgatttcttc taagatggcc gggaagttta tggaagctat
    15481 ttataatcaa aatggatttg tgctagagtc tttgactaaa acagattttg atagtcagcg
    15541 aattgccaaa ggtgtttctg ttaaagtagc tcataaaatt ggagatgcgg atgaatttaa
    15601 gcatgatacg ggtgttgtct atgcagattc tccatttatt ctttctattt tcactaagaa
    15661 ttctgattat gatacgattt ctaagatagc caaggatgtt tatgaggttc taaaatgagg
    15721 gaacaagatt ttttaaatca ttttctcaag aagggatatt tcaaaaagca tgctaaggcg
    15781 gttctagctc tttctggtgg attagattct atgtttctat ttaaggtatt gtctacttat
    15841 caaaaagagt tagagattga attgattctg gctcatgtga atcataagca gagaattgaa
    15901 tcagattggg aagaaaagga attaaggaag ttggctgctg aagcagaact tcctatttat
    15961 atcagcaatt tttcaggaga attttcagaa gcgcgtgcac gaaattttcg ttatgatttt
    16021 tttcaagagg tcatgaaaaa gacaggtgcg acagctttag tcactgccca ccatgctgat
    16081 gatcaggtgg aaacgatttt gatgcgcttg attcgaggaa ctcgcttgcg ctatctatca
    16141 ggaattaagg agaagcaagt agtcggagag atagaaatca ttcgtccctt cttgcatttt
    16201 cagaaaaaag actttccatc aatttttcac tttgaagata catcaaatca ggagaatcat
    16261 tattttcgaa atcgtattcg aaactcttac ttaccagaat tggaaaaaga aaatcctcga
    16321 tttagggatg caatcttagg catcggcaat gaaattttag attatgattt ggcaatagct
    16381 gaattatcta acaatattga tgtggaaaat ttacagcagt tattttctta ctctgagtct
    16441 acacaaagag ttttacttca aacttatctg aatcgttttc cagatttgaa tcttacaaaa
    16501 gctcagtttg ctgaagttca gcagatttta aaatctaaaa gccagtatcg tcatccgatt
    16561 aaaaatggct atgaattgat aaaagagtac caacagtttc agatttgtaa aatcagtccg
    16621 caggctgatg aaaaggaaga tgaacttgtg ttacactatc aaaatcaggt agcttatcaa
    16681 ggatatttat tttcttttgg acttccatta gaaggtgaat taattcaaca aatacctgtt
    16741 tcacgtgaaa catccataca cattcgtcat cgaaaaacag gagatgtttt gattcaaaat
    16801 gggcatagaa aaaaactcag acgtttattt attgatttga aaatccctat ggaaaagaga
    16861 aactctgctc ttattattga gcaatttggt gaaattgtct caattttggg aattgcgacc
    16921 aataatttga gtaaaaaaac gaaaaatgat ataatgaaca ctgtacttta tatagaaaaa
    16981 atagataggt aaaaaatgtt agaaaacgat attaaaaaag tcctcgtttc acacgatgaa
    17041 attacagaag cagctaaaaa actaggtgct caattaacta aagactatgc aggaaaaaat
    17101 ccaatcttag ttgggatttt aaaaggatct attcctttta tggctgaatt ggtcaaacat
    17161 attgatacac atattgaaat ggacttcatg atggtttcta gctaccatgg tggaacagca
    17221 agtagtggtg ttatcaatat taaacaagat gtgactcaag atatcaaagg aagacatgtt
    17281 ctatttgtag aagatatcat tgatacaggt caaactttga agaatttgcg agatatgttt
    17341 aaagaaagag aagcagcttc tgttaaaatt gcaaccttgt tggataaacc agaaggacgt
    17401 gttgtagaaa ttgaggcaga ctatacctgc tttactatcc caaatgagtt tgtagtaggt
    17461 tatggtttag actacaaaga aaattatcgt aatcttcctt atattggagt attgaaagag
    17521 gaagtgtatt caaattagaa agaataatct ttaatgaaaa aacaaaataa tggtttaatt
    17581 aaaaatcctt ttctatggtt attatttatc tttttccttg tgacaggatt ccagtatttc
    17641 tattctggga ataactcagg aggaagtcag caaatcaact atactgagtt ggtacaagaa
    17701 attaccgatg gtaatgtaaa agaattaact taccaaccaa atggtagtgt tatcgaagtt
    17761 tctggtgtct ataaaaatcc taaaacaagt aaagaaggaa caggtattca gtttttcacg
    17821 ccatctgtta ctaaggtaga gaaatttacc agcactattc ttcctgcaga tactaccgta
    17881 tcagaattgc aaaaacttgc tactgaccat aaagcagaag taactgttaa gcatgaaagt
    17941 tcaagtggta tatggattaa tctactcgta tccattgtgc catttggaat tctattcttc
    18001 ttcctattct ctatgatggg aaatatggga ggaggcaatg gccgtaatcc aatgagtttt
    18061 ggacgtagta aggctaaagc agcaaataaa gaagatatta aagtaagatt ttcagatgtt
    18121 gctggagctg aggaagaaaa acaagaacta gttgaagttg ttgagttctt aaaagatcca
    18181 aaacgattca caaaacttgg agcccgtatt ccagcaggtg ttcttttgga gggacctccg
    18241 gggacaggta agactttgct tgctaaggca gtcgctggag aagcaggtgt tccattcttt
    18301 agtatctcag gttctgactt tgtagaaatg tttgtcggag ttggagctag tcgtgttcgc
    18361 tctctttttg aggatgccaa aaaagcagca ccagctatca tctttatcga tgaaattgat
    18421 gctgttggac gtcaacgtgg agttggtctc ggcggaggta atgacgaacg tgaacaaacc
    18481 ttgaaccaac ttttgattga gatggatggt tttgagggaa atgaagggat tatcgtcatc
    18541 gctgcgacaa accgttcaga tgtacttgat cctgcccttt tgcgtccagg acgttttgat
    18601 agaaaagtat tggttggccg tcctgatgtt aaaggtcgtg aagcaatctt gaaagttcac
    18661 gctaagaaca agcctttagc agaagatgtt gatttgaaat tagtggctca acaaactcca
    18721 ggctttgttg gtgctgattt agagaatgtc ttgaatgaag cagctttagt tgctgctcgt
    18781 cgcaataaat cgataattga tgcttcagat attgatgaag cagaagatag agttattgct
    18841 ggaccttcta agaaagataa gacagtttca caaaaagaac gagaattggt tgcttaccat
    18901 gaggcaggac ataccattgt tggtctagtc ttgtcgaatg ctcgcgttgt ccataaggtt
    18961 acaattgtac cacgcggccg tgcaggcgga tacatgattg cacttcctaa agaggatcaa
    19021 atgcttctat ctaaagaaga tatgaaagag caattggctg gcttaatggg tggacgtgta
    19081 gctgaagaaa ttatctttaa tgtccaaact acaggagctt caaacgactt tgaacaagcg
    19141 acacaaatgg cacgtgcaat ggttacagag tacggtatga gtgaaaaact tggcccagta
    19201 caatatgaag gaaaccatgc tatgtttggt gcacagaatc ctcaaaaatc aatttcagaa
    19261 caaacagctt atgaaattga tgaagaggtt cgttcattat taaatgaggc acgaaataaa
    19321 gctgctgaaa ttattcagtc aaatcgtgaa actcacaagt taattgcaga agcattattg
    19381 aaatacgaaa cattggatag tacacaaatt aaagctcttt acgaaacagg aaagatgcct
    19441 gaagcagtag aagaggaatc tcatgcacta tcctatgatg aagtaaagtc aaaaatgaat
    19501 gacgaaa
//
LOCUS       DAYYYC010000043        18803 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.043, whole genome shotgun sequence.
ACCESSION   DAYYYC010000043 DAYYYC010000000
VERSION     DAYYYC010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18803
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.043"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(28..837)
                     /locus_tag="ACHBV5_001565"
     CDS             complement(28..837)
                     /locus_tag="ACHBV5_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFM9967331.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            complement(839..2188)
                     /gene="vicK"
                     /locus_tag="ACHBV5_001566"
     CDS             complement(839..2188)
                     /gene="vicK"
                     /locus_tag="ACHBV5_001566"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HFM9967332.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            complement(2181..2885)
                     /gene="yycF"
                     /locus_tag="ACHBV5_001567"
     CDS             complement(2181..2885)
                     /gene="yycF"
                     /locus_tag="ACHBV5_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFM9967333.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            complement(2940..4115)
                     /gene="mutY"
                     /locus_tag="ACHBV5_001568"
     CDS             complement(2940..4115)
                     /gene="mutY"
                     /locus_tag="ACHBV5_001568"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFM9967334.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            complement(4443..6113)
                     /locus_tag="ACHBV5_001569"
     CDS             complement(4443..6113)
                     /locus_tag="ACHBV5_001569"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFM9967335.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKSQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            6343..7032
                     /gene="coaB"
                     /locus_tag="ACHBV5_001570"
     CDS             6343..7032
                     /gene="coaB"
                     /locus_tag="ACHBV5_001570"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFM9967336.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            7044..7595
                     /gene="coaC"
                     /locus_tag="ACHBV5_001571"
     CDS             7044..7595
                     /gene="coaC"
                     /locus_tag="ACHBV5_001571"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFM9967337.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            7579..8142
                     /locus_tag="ACHBV5_001572"
     CDS             7579..8142
                     /locus_tag="ACHBV5_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFM9967338.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            8424..8951
                     /locus_tag="ACHBV5_001573"
     CDS             8424..8951
                     /locus_tag="ACHBV5_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFM9967339.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            8963..9478
                     /locus_tag="ACHBV5_001574"
     CDS             8963..9478
                     /locus_tag="ACHBV5_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFM9967340.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(9475..9942)
                     /locus_tag="ACHBV5_001575"
     CDS             complement(9475..9942)
                     /locus_tag="ACHBV5_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HFM9967341.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(10016..10504)
                     /locus_tag="ACHBV5_001576"
     CDS             complement(10016..10504)
                     /locus_tag="ACHBV5_001576"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9967342.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQTWRESYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            complement(10470..11033)
                     /locus_tag="ACHBV5_001577"
     CDS             complement(10470..11033)
                     /locus_tag="ACHBV5_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFM9967343.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNIGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            complement(11043..13031)
                     /gene="uvrB"
                     /locus_tag="ACHBV5_001578"
     CDS             complement(11043..13031)
                     /gene="uvrB"
                     /locus_tag="ACHBV5_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFM9967344.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(13108..14061)
                     /locus_tag="ACHBV5_001579"
     CDS             complement(13108..14061)
                     /locus_tag="ACHBV5_001579"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HFM9967345.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            14231..16396
                     /locus_tag="ACHBV5_001580"
     CDS             14231..16396
                     /locus_tag="ACHBV5_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFM9967346.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            16396..17136
                     /locus_tag="ACHBV5_001581"
     CDS             16396..17136
                     /locus_tag="ACHBV5_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFM9967347.1"
                     /translation="MVKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            17285..18772
                     /gene="zwf"
                     /locus_tag="ACHBV5_001582"
     CDS             17285..18772
                     /gene="zwf"
                     /locus_tag="ACHBV5_001582"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFM9967348.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
BASE COUNT         5628 a         4165 c         3433 g         5577 t
ORIGIN      
        1 aaaaagaaca ccttctcagc gttctttcta tatctctgtc aatggtgttg cggtatctgg
       61 tgaggtatca taaaccttaa agtctactcc gactcccaga tcagcttgag ccagctgatt
      121 gaccatggtc atatgagcca gttccttgat attgttttcc ttagataaat gcccaaggta
      181 aatcttctta gtacgatttc ctagcgtccg aatcatagct tcagcaccgt cctcgttaga
      241 aaggtgacca aggtcagata ggattcgttg tttgagtcgc caagcgtaag aacctgatcg
      301 caaaatctct acatcatggt tggcctcgat aagataacca tccgcatttt cgacaatgcc
      361 cgccatacgg tcactgacat aacctgtatc tgtcaagagg acaaaactct tatcatcctt
      421 cataaagcga tagaactgcg gtgcgactgc atcatggctt acaccaaaac tctcgatgtc
      481 gatatctcca aaggttttgg ttttacccat ttcaaaaata tgcttttgcg aagaatccac
      541 cttgccaaga tatttactat tttccatagc ttgccaggtc ttttcattgg cataaagatc
      601 cataccatac ttgcgagcca aaacgcctac tccatggata tgatctgaat gctcatgggt
      661 aatcaagatg gcatccaggt cttctggctt acggttaatt tcagctagca gactggtaat
      721 tttcttgcca gacaagcctg catctactaa aagcttcttt tttgaggttt ccagataaaa
      781 agaatttcca ctggaacccg acgctaaaat actgtattta aagcctattt cactcattct
      841 agtcttctac ttcatcctcc catacttctt ctttcactgc atccttatca taagggagta
      901 caatggtaaa ggttgaaccc ttgccgtatt cactcttggc ccaaataaag cccttatgtt
      961 gtttgataat ttctttagcg atagacagtc ctagacctgt accaccttgt gcacgacttc
     1021 tagcacgatc cacacgatag aaacggtcaa agatacgtgg taaatcctgc ttaggaatcc
     1081 ccaaaccgtg gtcagaaatg gataaaatca tctggtcttc agttgtcttc attctgacag
     1141 tgattttacc cccatctggc gaatacttaa tagcattatt taaaatattg tcgacaacct
     1201 gcgtcatctt atctgtatca atttccatcc agatagaatt gatgggataa tctctcacca
     1261 gctcatattt tttctccttt tcctgtcctt tcatcttgtc aaaacgattg aggataaagg
     1321 taataaaagc agtgaagtta atcagttcca catctaggtg actggtagca ttatcaatac
     1381 gtgaaagatg gaggagatcc gtcaccatgc gcatcatacg gttggtctca tcaagagaaa
     1441 ccttgataaa gtctggtgct acagtttcac acaaagcccc ctcatccaag gcttcaagat
     1501 aggattttac gctagtcaga ggagtccgta actcatggct aacattggaa acaaagagtc
     1561 ttcgttcgcg ttcttccttc tcctgctccg tcgtatcatg caaaacagcc accaaacctg
     1621 aaataaagcc agactctcga cgtatcaagg caaagcgaac tcgaaggttc aaatattcgc
     1681 cattgatatc ttgggaatct agcaacaatt ctggactttg ggtaatcaaa tcacgcaatt
     1741 catagttttc ttctatcttg agcaattcca aaatgcttct attcagaaca tcttccttaa
     1801 ccaaccccag ttgcttcttg gctgtatcgt taatcatgat aatctgaccc cgacggttag
     1861 tcgcaagaac cccatctgtc atataaaaca gaatactatt tagcctctta ctctcttgtt
     1921 ctagattttc ctgagtgaga cgaataacct ccgacaagtc attcaaatta ttggtaatat
     1981 tggtgatttc agacccacct tgcatatcaa gaaccttgga ataatctcct gcaatcaaat
     2041 ctttaacctt ttgattgatt tgcttcaact gaatattatc acgtctattt tccagtaata
     2101 agagggtcac aacaaggatg aaacctaaca aaatcaggat aaagataaaa tctctggtaa
     2161 aaatggtttg tttcagtaaa tcaagcatta tttctcatgt aataccctac accacggcgc
     2221 gtcaagatat actctggtcg gctgggcgta tcttcaatct tctcacgcag acgtcgtaca
     2281 gtcacatcaa ctgtgcggac atcaccaaaa tagtcataac cccagacagt ctcaagcaag
     2341 tgttcgcgcg tgatgacttg acctgtatgc gatgctaaat gatacaaaag ctcaaattca
     2401 cgatgggtta agtctagttc ttcgccatat tttttagcca cgtaggcgtc tggaacaatt
     2461 tctaaatccc caatttggat aggttgaggt ttactatctg cttcctgacc atctactggc
     2521 ataggttgag aacgacgcag aagagcttta acacgcgcct gcaactcacg attggagaag
     2581 ggtttcgtta catagtcatc tgccccaagt tccaaaccga taaccttatc aaattcacta
     2641 tctttggctg aaagcataag aatgggcaca ctgcttgtct tacgaatggt cttagcaact
     2701 tctaaaccat caatttctgg aagcatcaaa tccagaataa taatatctgg ttgctctgct
     2761 tcaaattgct ctagcgcttc acgaccatta aaagcagtta caacttcata accttccttg
     2821 gtcatattaa acttgataat atccgagatt ggtttctcat catctacaat tagtattttt
     2881 ttcatatgtt cacctttttc tctactatta taccaaaaaa tagtcagaag acacaatagc
     2941 tagtcttggc tactgtctaa gttggcttgt gcataagcct gccagatttt ttgttggggt
     3001 ttggcaagtg ggtaattctt gaattcttct ggtgaaagcc aacgaacttc cctatctgaa
     3061 aaatcatgga agtcactcac ctgacctgct acaatctgta catgccattt tcgatgacta
     3121 aaaacatgct ggactgtatc aaaacaaaca tcaagccaat caacatctag gtcatagtcc
     3181 tgctggaaac tctcttctgg actggggcca aagttcacac tttcttccgc aacctgatga
     3241 aagaggtcaa actgctcttc ttgcgaaaag ttatcaactt ctataaaggg gaaatgccaa
     3301 aaacctgcca agagcttttc gctttcattt ttttcaagta aaaattgtcc ttgagaattt
     3361 ttcacaacta aggctttaag ataaatagga accggctttt tcttaggaga tttaattgga
     3421 taacggtcca tggttccatt ctgatatgcc gcactaaagt ccttgactgg gctttcttca
     3481 ggtctgggat ttacaggaga ctcaatatca gaccctaagt ccatcaaggc ttgattaaaa
     3541 tcacccggac gatccggatt aatcaagatc tccatcattg cctgaaaaat ttttcgatta
     3601 cttggaatcc caatatcgtg gttgacttca aacagacgcg ccaagacccg catgacatta
     3661 ccatctacag ctggctcagg caagttaaaa gcaatactgg aaatggctcc tgctgtgtaa
     3721 ggtccaatcc ctttcaagct ggaaattcct tcataggtat ttggaaattg gccaccaaag
     3781 tcagtcataa tctgctgggc tgcagcctgc atattgcgaa ctcgagaata atagcccaag
     3841 ccctcccaag ctttcagtaa actctcctca ggcgcagttg ccagactttc gacagttgga
     3901 aaccagtcca ggaatctttc gtagtaaggg ataactgtat ccaccctggt ctgctgaagc
     3961 atgatttcag atacccagat gtgataagga tttttacttc tcctccaagg caaatctctt
     4021 ttgttttcat cataccaagc gagaagtttc tcacggaaag aaatgacttt ctcctccggc
     4081 cacatgacga taccgtattc tttcaaatct aacatatctc tagtataaca cagaaggttt
     4141 cacctgtctt tgtatctgat ttataatatt ttcaatagat agtatataac ttttctatct
     4201 acttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt tgctcaaaac
     4261 actgttttga ggttgtggat agaactgaca gagtcagtat catataccta cggcaaggtg
     4321 aagctgacgt agtttgaaga gattttcgaa gagtataaat cttattgatg aactgcttgc
     4381 agtctgagaa aaaatgagct tggatattat ttccaaactc acttaaagtc aatttcaatc
     4441 cactagaaca agcctagtac agttccatcg ctttcaacat ccatgttgag agctgctgga
     4501 cgttttggaa gacctggcat ggtcataaca tcaccagtta aggcaacgat gaagcctgca
     4561 cctaattttg gtaccaattc acgaatggta atttcaaagt tttctggtgc tccaagcgca
     4621 tttggattgt ctgagaaact gtattgagtt ttagccatac agattggcaa tttgtcccaa
     4681 ccgttttgaa cgatttgagc aatttgtgtt tgagatttct tctcaaagtt cactttgcta
     4741 ccacgataga tttcagtgac aattttttca atcttttctt ggacagaaag gtcattatcg
     4801 tacaaacgtt tatagttagc tggattttca gcaattgtct taacaactgt ttcggcaagt
     4861 gctactccac cttctgctcc atcagcccag acactagcca attcaactgg tacatcgatt
     4921 gaggcacaga gttcttttaa gactgcaatt tcagcttctg tatcagatac aaattcgtta
     4981 atagctacaa ctgctggaat accgaactta cggatatttt caacgtggcg tttcaagtta
     5041 gcaaaacctg cacgaactgc ctctacattt tcttcagtca gagcgtcttt agccacacca
     5101 ccattcatct taagggcacg aagggttgcg acaataacaa ctgcatctgg agatgttggc
     5161 aagtttggtg tcttgatatc aaggaatttc tcagcaccaa ggtccgcacc aaaaccagct
     5221 tcagtaacag tgtaatcagc caagtgaagg gctgttgtcg tcgccaaaac agagttacag
     5281 ccatgagcga tattggcaaa tggaccaccg tgtacaaagg caggtgtacc gtaaattgtc
     5341 tgaaccaagt ttggcttaat agcatccttc aaaatcaaag ccaaggcacc ctcaacctgc
     5401 aaatcaccta cagaaacagg cgtacggtca tagcgataac caataacgat attcgccaaa
     5461 cgacgtttca agtcctcgat gtccgttgcc aagcaaagaa ttgccatgat ttctgaagca
     5521 actgtaatat caaaaccatc ctcacgtgga ataccgttta gaggaccacc aagaccaaca
     5581 gtcacatggc ggagcgcacg gtcgttcaag tccacaacgc gtttccagag gatacgacgt
     5641 tgatcaattc ccagctcatt cccttggtgc aagtggttgt caatcaaggc agaaagggca
     5701 ttgttggcag ttgtaatagc atgcatatct ccagtaaagt ggaggttgat gtcttccatt
     5761 ggcagaactt gtgcataccc accaccagca gcaccaccct tgatccccat gactggacca
     5821 agagacggtt cgcggatagc aatcatggtt ttcttgccaa tcttgttcaa ggcatccgca
     5881 agaccaatgg taagcgtcga ctttccttca cctgcaggtg ttgggttgat ggcagtaacc
     5941 aagatcaatt taccgactgg attgctctca actgcccgaa ttttatcaaa gctgagttta
     6001 gccttgtact ttccgtacaa ctccaaatcg tcgtaagaaa taccaagttt ctctacaaca
     6061 tcaacaattg gcttcaactc aatactctgt gcgatttcaa tatctgtttt cattcaaaat
     6121 tcctctaacc tcttatatga taattcatta tatcacaaaa caagattttt aacatcttaa
     6181 aactctctaa acgttcgtaa atatctctgt ttttaagact tttagagtcc tttcttaaat
     6241 tttatatggc tttatagttt gaaactatag taaatcttcg tttttaccaa aaatttatca
     6301 ctttcatttt acttaccgct tatttttgtg tacaatagtg ctatgaaaat tttagttaca
     6361 tcgggcggta ccagtgaagc tatcgatagc gtccgctcta tcactaacca ttctacaggt
     6421 cacttgggga aaattatcac agagactttg ctttctgcag ggcatgaagt ttgtttaatt
     6481 acgacaaaac gagctctgaa gccagagcct catcctaacc taagtattcg agaaattacc
     6541 aataccaagg accttctaat agaaatgcaa gaacgtgttc aggattatca ggtcttgatc
     6601 cactcaatgg ctgtttctga ctacactcct gtttatatga cagggcttga ggaagttcag
     6661 gctagctcca atctaaaaga atttttaagc aagcagaatc atcaggccaa gatttcttca
     6721 actgatgagg ttcaggtttt gttccttaaa aagacaccca aaatcatatc cctagtcaag
     6781 gaatggaatc ctactattca tctgattggt ttcaaactgc tggttgatgt taccgaagat
     6841 catctggttg acattgcacg aaaaagtctt atcaagaatc aagcagattt aatcatcgcg
     6901 aatgacctga ctcaaatttc agcaggtcag caccgagcta tatttgttga gaaaaatcag
     6961 cttcaaacag tccagactaa agaagaaatt gcagaactcc tccttgaaaa aattcaagcc
     7021 tatcattctt agaaaggaaa actatggcaa acattctctt ggctgtaacg ggttcaatcg
     7081 cctcttataa gtcggcagat ttagtcagtt ctctaaaaaa acaaggccat caagtcactg
     7141 tcttaatgac tcaggctgct acagagttta tccaaccttt gacactacag gtactctcac
     7201 agaatcctgt ccacttggat gtcatgaaag aaccctatcc tgatcaggtc aatcatatcg
     7261 aacttggaaa aaaagcagat ttatttatcg tggtacctgc aactgctaac actattgcaa
     7321 aactagctca cggatttgcg gacaacatgg taaccagtac agctctagcc ctaccaagtc
     7381 atattcccaa actaatagct cctgctatga atacaaaaat gtatgaccat ccagtaactc
     7441 agaataatct gaaaacatta gaaacctacg gctatcagct gattgctcct aaggaatccc
     7501 tactagcttg tggagaccac ggacgaggag ctttagctga cctcacaatt attttagaaa
     7561 gaataaagga aactatcgat gaaaaaacgc tctaatattg cacccattgc tatctttttt
     7621 gctaccatgc tcgtgataca ctttctgagc tcacttatct ttaacctttt tccatttcca
     7681 atcaaaccga ccattgttca tattcctgtc attattgcca gcattattta tggtccacga
     7741 gttggggtta cacttggatt tttgatggga ttacttagct tgacggttaa cacgattacg
     7801 attctaccga caagctacct cttctctccc ttcgtaccaa acggaaacat ctactcagct
     7861 atcattgcca ttgtcccacg tattttgatt ggtttaactc cttacttagt ctataaactg
     7921 atgaaaaaca agactggtct gattttagct ggggctcttg gttccttgac aaatactatc
     7981 tttgtccttg gaggaatctt cttcctattt ggaaatgttt ataatggaaa tatccaactt
     8041 cttctggcaa ccgttatctc aacaaattca attgctgaat tggtcatttc tgcaattcta
     8101 accctagcca ttgttccacg actacaaacc ttgaaaaaat aaaaacaatc tccgctttca
     8161 aacctgaagg tggagatttt gctctataca gtttcttttt aatgaaatct ttactatagt
     8221 aaaacgaaat aagaacagga caaatcgatc aggacagtca aatcgatttc taacaatgtt
     8281 ttagaagtag aggtggacta ttctagtttc aatctactat aacttttaac taaaaaatga
     8341 tctataaacc caagtaaatt cttgctttat tgtctggttt attgtaccat actagtgtat
     8401 atgcagttaa aaaggagatt cttgtgaata cacggaaaaa gacacaattt atgacaatga
     8461 cagccctttt aacggctatt gcgattttga ttccaattgt tatgcctttc aagattgtca
     8521 ttccacctgc ttcctatact ttggggagcc acatcgctat ttttatagcc atgttcttgt
     8581 cgcccttgat ggcagttttt gtcatcctag cctctagttt tggatttttg atggctggct
     8641 atcccatggt tatcgttttt cgggcttttt cccatatatc ttttggtgct ttaggagctc
     8701 tttacctaca aaaattcccc gataccctag ataaaccaaa atcttcctgg gttttcaatt
     8761 ttgttttggc tgttgttcat gcccttgctg aagtattagc ctgtgtcctt ttttacgcaa
     8821 cttcgggtac caatgtagaa aatatgttct atgttctatt tgtactagtt ggatttggca
     8881 caattatcca tagtatggta gactatacat tagcactagc tgtctataaa gtgcttcgaa
     8941 aacgccgtta aaaggaaaag ctatgacaaa agatcgcaaa caagccctgc tccaactctt
     9001 gaaagaagct cctaaagccc ttaatggcca aagtttggcg gaacattttc atgtcacacg
     9061 tcaggtcatt gtgcaggaca ttgcaatttt gagagccgat ggcgctccta tcctatccac
     9121 caatcgtggc tacatctata agcaaattga taccaatcct tatgttcaca aacttttcaa
     9181 agtgaaacat gaagttgaag aaatcggtca ggaactcctt gctattgtcg ataatggtgg
     9241 gcatgtccag aataccttga ttgaccatcc cgtttatgga gaaattgaaa ccttgcttaa
     9301 actgtcttgt cgcagagatg tgcaacattt tctagaacaa gtcgagcatt ctgactttag
     9361 acctctatct gaattgacag atggcatcca ttaccaccta gtcgaagccg aaacacaaca
     9421 agacctccac tatatcgagg aggccttgga tcagctaggt tatttagtaa aagactagaa
     9481 gattttcttt tcccaatcgt cttctgtacg gcgaggatag aaaaactctg acttgtcggg
     9541 agcttccatc atttccatca atggtagcat atcataggcc agatttaagt ttggaatctg
     9601 gtctttttgc acccaagaaa cttctccctc ttctgaagat tgaagggtac cagagaactc
     9661 agtcgcctta taacaaatga caatatagcg cccacctgta tctagtggcc aatttttaat
     9721 gccgacaagt tgaggatttt ggatagtcaa ccctgtttct tcgtagattt cacgaatgac
     9781 agactccgca aaagcctcat cattttctac atgacctcca ggaaaggcat aaccagacca
     9841 gcgattgttt tcaggggcgc gatactgcat caccacgcgc tgagtttcga ggtcttcaat
     9901 cagacagata tttgttaaaa ttgttaattg ggaacgggac ataaatttac tcgctttcta
     9961 atttattaaa ttttcagact tactaccaga gatattatct tttacttttt taaaattatt
    10021 tagaatagaa caccattcgt ttttccttta taggctttcc aagttcaagt attttttctt
    10081 gtccatcaaa agtaaaaccc attttttgat agaaagcaat ggcgcgcttg ttatctttca
    10141 atacccataa gaaaatttca gaaaaatgat taagagcagt caaagctgct ttcattaact
    10201 tttgtgcgat accttttcca taatagtctt ttaaaacata taaagcaata atttcaccag
    10261 cttgaatagt ctcatcacga aaattgccat aactgataaa accaaccacc ttcacgccat
    10321 ccatcgcaat caatgtattt tctggatact tttgactaaa gaatcgacat ctttctaatg
    10381 tcattgtatc ctgaaattcc gcaggcaaaa ggtcatcata agactctctc cacgtttgcc
    10441 agtgaacaag ggatttacct tctatctctt taggagtttc cattgatttg ataataaccg
    10501 tcatttattt tctcccagtc ttctctcaaa ataccatatt taatactatc aaaatattta
    10561 ccttgataat aacgaacttt tggaatatga gcttcttttt tcattcttaa tttttcagca
    10621 agtttcatca taccaatatt ccctgaccaa gttgtcaaac ccagatgctc caactccaag
    10681 taatcctgaa acgtcctatc tatccactgc aacatagcaa ctttcccaat accagtgttc
    10741 cagaattttt tatcataaat accaattccc aattccatcc atcttgtttg tttacatacc
    10801 caataacgcg aaacagtccc aactagttta tcatcaacaa aaataccaag gcgatttgag
    10861 ttgcttaaaa tggattctga tttttgtagt tcgaattctt taaaatttga aaaatactga
    10921 taatcatcat aatagggagc atcatactgt ttccaaactg gattaagttg tgaataagcc
    10981 atttcccata aagacatcaa atcttctctc tttaactttc ttaaataaat catactattc
    11041 ccctaatcca aggccttgac ttccaacatc atatcacgga tctgagccgc cagttcaaag
    11101 tcaagcactt cgacggcttc ttgcatttgt ttttctagtt tcttgacgag ttctttgcgc
    11161 tcttgtttgt tgaggctatt gatgtcgact tccttgtcct cttccttagc aactgccttg
    11221 gtcacggcaa tcaggtcacg gatttctttc ttgattgtct gtggtacgat accatgctct
    11281 tcattatagg ccatctgaat tttccgacgg cgggcagttt catcgatagc acgttgcata
    11341 gactgggtaa ccgtgtctgc atacatgatg acatggcctt cactgttacg agcagcacgt
    11401 ccaatagtct ggatgagtcc acgttcgttg cgaaggaaac cttccttgtc agcatcgaga
    11461 atagctacga ggctcacttc aggaacgtca attccttcac ggagcaggtt aattccgacc
    11521 aagacatcaa agacacccaa gcgcaggtca cggataatct ccgtccgttc caaggtcttg
    11581 atatccgagt gcatgtactt gaccttgata cccatttcct tgaagtagtc ggtcaaatcc
    11641 tctgccattt tcttggtcaa agttgtgata aaggtacgct catttttttc aacgcgggca
    11701 ttgatttcac ccaagaggtc atcaatctgt cccatagtcg gacggacttc cacctctgga
    11761 tccaagagtc ccgttggacg aatgatttgc tcaatcactg tctcggtctg ttcattttca
    11821 tagtcaccag gtgtcgctga aacgtaaaca atctgatgaa cgtgactctc aaactcctcc
    11881 cgacggagag gacgattgtc caaagcagac ggcaaacgga aaccataatt aaccagcatt
    11941 tctttacgcg aacggtctcc attgtacatg cccttgattt gccctatggt catatgactc
    12001 tcgtcaatca taatcaagaa atcatctggg aagaagtcga gaagcgtata aggaggctct
    12061 ccttcgctcc gtccatccat gtggcgagaa taattttcaa ccccattggt atagcccatc
    12121 tcacgcaaca tttcgatatc atactctgtc cgctgtttca aacgctgggc ttcaagcagt
    12181 ttaccttcct tttcaaagac agctaattgt tcttccaact cggcctgaat ctttgcaatg
    12241 gcaacttcca tgtggtcgtc attggtcaca aagtgtgtcg ctgggaaaat cgctaaatga
    12301 tccacttctc ccaacacctg acctgtcaga gcctcaactt cacgaatacg gtcaatttcg
    12361 tctccaaaaa attctactcg aaaggcatgt tcatctcggg aagctgggaa aatctctacc
    12421 acatccccac gaacgcgaaa tcttccgcgt tggaaatcaa tatcattacg ttcaaactga
    12481 atatcgacca agtcattcaa gagtttatca cgagaaatct ctagaccagg acggagacta
    12541 acgacactat cagcgtattc cttgggcgaa cccaaaccat agatacaaga gactgaggcc
    12601 acgacaataa catcattacg ctccaaaagg gctgaggtag ctgagtggcg aagcttgtca
    12661 atctcgtcat tgacagaact atccttctca atataggtat cgctagaagg gacataggcc
    12721 tctggctggt aataatcata gtaggatacg aaatactcaa ctgcattttc agggaaaaat
    12781 tccttaaact ccccatagag ctgaccagcc agagttttat tgtgggcaat aaccagagtt
    12841 ggtttattga ctttagaaat gacctgactc atagtatagg tcttccctgt tccagtcgcc
    12901 cccatcagaa tctgagcttt ttctcccccc tcaatgttat ccaccaactg ctcgatagct
    12961 tggggttgat ctcctgatgg ttgatatttt gatactagtt taaattgatt atctgtaatg
    13021 tgattgatca taagaatcct ctctccatgt gctattccta ttttagcata cttatagtat
    13081 tttcacgaag aaaaggacgg accgaagtca catcctttca ttttctttct ttaatttatt
    13141 agcaagatag acaatcagca gtagtaatac cagacttgtc ataatggaac cttctatgcc
    13201 aaaagaacca cctgatagcc aatcttgatt gccttgtggt aaaaaggtca tcagagacgt
    13261 tcctgacggt tgaccactaa ctaaaatccc aaagagatta ccctgagcaa aattccaagc
    13321 accatgaata cctgcaacac cccaaactgt atcagttttg agaaggtaaa gagccatggc
    13381 aactccgaat aaaaagagat ttactagaga tagaggggtg agaccagaat tgcccatatg
    13441 aagcagggta aagaacaggc tagatataag aatagctagt tttagattgg ttcttgaggc
    13501 caattgagga agtagccaag cacgggccac cacttcttct gctgtcccct gtaaaatcca
    13561 aaatgggata gtaaagacga caaaggcaag agaataagga ttcaagtgaa tggattccaa
    13621 acgatattga cctaagacca ctaaacctaa caaggtcaga agaaaaagtg ccaggcctag
    13681 actaaatcct ttcagaagat tgctgaggaa attctctcta taaaatccca aggttcgaat
    13741 aggtcttttc tcaacttttc ttgtccatct gaacacagtg ttaagaataa aaccaaaggc
    13801 cagtaatcct aaaattaaac gaaagtcact tgttttatcc gtcaagctct gatgcaaggt
    13861 ctgcaagtag cttgcaagat tttgaccagc ctctccaaaa tttctagcaa gtccgatgag
    13921 agctaacaag ccaataccat acaaagtaaa agccacaaac tctcctatga agacaaaaac
    13981 aaaggctaac aaggggcttg tgtaaatgtt taaactcatt tttgaagctt ggaagtcttt
    14041 aaatattctt ttgttcttca tatccccgtc ctcttttctt ctatatatac tattattata
    14101 gcacttttta atagcaattc aaggaaagga aaaaatcgat gttatatttt ctgacacgaa
    14161 aaatataaaa atttgccttt ttttactttt tctgatataa tgagagaata ttcggaaaag
    14221 gagactaaaa atgaagaaaa aatttctagc atttttgcta attttattcc caattttctc
    14281 attaggtatt gccaaagcag aaacgattaa gattgtttct gataccgcct atgcaccttt
    14341 tgagtttaaa gattcagatc aaacttataa aggaattgat gttgacatta ttaacaaagt
    14401 cgctgagatt aaaggctgga acattcagat gtcctatcct ggatttgacg cagcagtcaa
    14461 tgcggttcaa gctgggcaag ccgacgctat catggcaggg atgacaaaga ctaaagaacg
    14521 tgaaaaagtc ttcaccatgt ctgatactta ctatgataca aaagttgtca ttgctactac
    14581 aaagtcacac aaaattagca agtacgacca attaactggc aaaaccgttg gtgttaaaaa
    14641 cggaactgcc gctcaacgtt tccttgaaac aatcaaagat aaatacggct ttactattaa
    14701 aacatttgac actggtgatt taatgaacaa cagcttgagt gctggtgcca tcgatgccat
    14761 gatggatgac aaacctgtta tcgaatatgc cattaaccaa ggtcaagacc tccatattga
    14821 aatggatggt gaagctgtag gaagttttgc tttcggtgtg aaaaaaggaa gtaaatacga
    14881 gcacctggtt actgaattta accaagcctt gtctgaaatg aaaaaagatg gtagtcttga
    14941 taaaattatc aagaaatgga ctgcttcatc atcttcagca gtgccaacta caactactct
    15001 cgcaggatta aaagctattc ctgttaaggc taaatatatc attgccagcg attcttcttt
    15061 tgcacctttt gttttccaaa attcaagcaa ccaatacact ggtattgata tggaattgat
    15121 taaggcaatc gctaaagacc aaggttttga aattgaaatc accaaccctg gttttgatgc
    15181 tgctatcagt gctgtccaag ctggtcaagc cgatggtatc atcgctggta tgtctgtcac
    15241 agatgctcgt aaggcaactt ttgacttctc agaatcatac tacactgcta ataccattct
    15301 tggtgtcaaa gaatcaagca atattgcttc ttatgaagat ctaaaaggaa agacagtcgg
    15361 tgttaaaaac ggaactgctt ctcaaacctt cctaacagaa aatcaaagca aatacggcta
    15421 caaaatcaaa acctttgctg atggttcttc aatgtatgac agtttaaaca ctggtgccat
    15481 tgatgccgtt atggatgatg aacctgttct caaatattct atcagccaag gtcaaaaatt
    15541 gaaaactcca atctctggaa ctccaatcgg tgaaacagcc tttgccgtta aaaaaggagc
    15601 aaatccagaa ctgattgaaa tgttcaacaa cggacttgca aaccttaaag caaacggtga
    15661 attccaaaag attcttgaca aatacctagc tagcgaatct tcaactgctt caacaagtac
    15721 tgttgacgaa acaacgctct ggggcttgct tcaaaacaac tacaaacaac tccttagcgg
    15781 tcttggtatc actcttgctc tagctcttat ctcatttgct attgccattg tcatcggaat
    15841 tatcttcggt atgtttagcg ttagcccata caaatctctt cgcgtcatct ctgagatttt
    15901 cgttgacgtt attcgtggta ttccattgat gattcttgca gccttcatct tctggggaat
    15961 tccaaacttc atcgagtcta tcacaggcca acaaagccca attaacgact ttgtagctgg
    16021 aaccattgcc ctctcactca atgcggctgc ttatatcgct gaaatcgttc gtggtggtat
    16081 tcaggccgtt ccagttggcc aaatggaagc cagccgaagc ttgggtatct cttatggaaa
    16141 aaccatgcgt aagattatct tgccacaagc aactaaattg atgttgccaa actttgtcaa
    16201 ccaattcgtt atcgctctta aagatacaac tatcgtatct gctatcggtt tggttgaact
    16261 cttccaaact ggtaagatta tcattgctcg taactaccaa agtttcaaga tgtatgcaat
    16321 ccttgctatc ttctatcttg taattatcac acttttgact agactagcga aacgcttaga
    16381 aaagaggatt cgttaatggt aaaattaaaa attgatgtaa atgatttaca caagcactat
    16441 ggaaaaaatg aagtcctaaa aggaattacg actaagttct atgaaggaga tgttgtttgt
    16501 atcatcggtc cttcaggttc tggtaagtca actttcctcc gtagcctcaa tcttttagaa
    16561 gaagtcacta gcggtcacat cactgtgaac ggctatgatt taactgaaaa aacaaccaat
    16621 gttgaccacg tccgtgaaaa tatcggcatg gtattccaac acttcaacct cttccctcat
    16681 atgtctgtat tggacaacat cacctttgct cctattgagc acaagttgat gactaaggaa
    16741 gaagctgagg aattgggaat ggagttgctt gaaaaggttg gactagcaga taaagctaat
    16801 gccaatccag atagcctatc aggtggtcaa aaacaacgtg tggccatcgc tcgtggccta
    16861 gcaatgaatc cagacatcat gctcttcgat gaaccaactt ctgcccttga ccctgagatg
    16921 gttggagacg tacttaacgt tatgaaggaa ttggctgagc aaggcatgac catgattatc
    16981 gtaacccatg agatgggatt tgctcgtcag gttgccaacc gcgttatctt tactgcagat
    17041 ggcgagttcc ttgaagacgg aacacctgac caaatctttg ataacccaca acaccctcgt
    17101 ctgaaagagt tcttagataa ggtcttaaac gtctaaactc aaactgtaag gatttccttg
    17161 cagtttttct acctcgtatt ggaatttttg atttttcgga aaattatgtt agaattaagt
    17221 ttatgaaatg aggtttcctc atacctagca agactaggaa taaaaataga aattaggtag
    17281 ctagatgtca tctaaggtta ttgttacaat tttcggtgcg agtggagacc tggctaaacg
    17341 caagctctac ccttcccttt ttagactata tcaatccggc aatctttcca agcactttgc
    17401 cgttattgga actgcccgta gaccttggag taaggaatat tttgaatctg tagttgtcga
    17461 gtccatcctt gatttggcag atagtaccga gcaagcccaa gaatttgcta gccacttcta
    17521 ctatcaaagc catgatgtca atgattcgga acattatatt gctttgcgtc aattacaagc
    17581 tgagcttaat gaaaaatacc aagctgaaca caataagctc ttcttcttgt ctatggcacc
    17641 tcagttcttt ggaaccattg ccaaacacct caaatctgaa aacattgtcg atggcaaagg
    17701 ttttgagcgc ttgatcgttg aaaaaccatt tggtacagat tacgcaactg caagcaagtt
    17761 gaatgacgaa ctcctagcaa catttgacga agaacaaatt ttccgtatcg accattatct
    17821 tggtaaggaa atgatccaaa gcatctttgc agttcgcttt gcaaacttga tttttgaaaa
    17881 cgtttggaac aaggatttta tcgacaatgt tcaaattacc tttgcggagc gcttgggtgt
    17941 agaagaacgt ggtggctact atgaccaatc cggtgccctc cgtgacatgg tccaaaacca
    18001 cactctacaa cttctttcgc tcctcgccat ggacaaacca gcaagcttca caaaagacga
    18061 gattcgtgct gaaaagatta aggtctttaa aaacctctat catccaactg atgaagaact
    18121 caaagaacac tttatccgtg ggcaataccg ctctggtaag attgatggca tgaaatacat
    18181 ctcttatcgt agcgagccaa atgtgaatcc agaatcaaca actgaaacct ttacatctgg
    18241 tgccttcttt gtagacagcg atcgattccg tggtgttcct ttctttttcc gtacaggtaa
    18301 acgactgact gaaaaaggaa cccatgtcaa catcgtcttt aaacaaatgg attctatctt
    18361 tggagaacca cttgctccaa atattttgac catctatatt caaccaacag aaggcttctc
    18421 tcttagccta aatgggaagc aagtaggaga agaatttaac ttggctccta actcacttga
    18481 ttaccgtaca gatgcgactg caactggtgc ttctccagaa ccatacgaaa aattgattta
    18541 tgatgtccta aataacaact caactaactt tagccactgg gatgaagttt gtgcgtcatg
    18601 gaagttgatt gaccgtattg aaaagctctg ggctgaaaat ggtgccccac ttcatgacta
    18661 taaagctgga agcatgggac ctcaagccag ctttgaccta cttgaaaaat tcggtgccaa
    18721 atggacttgg caaccagata tcacctatcg tcaagatggt cgcttagaat aaaaaaattt
    18781 cctgcaagtt tatgccttgc agg
//
LOCUS       DAYYYC010000044        18202 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.044, whole genome shotgun sequence.
ACCESSION   DAYYYC010000044 DAYYYC010000000
VERSION     DAYYYC010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18202
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.044"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(75..227)
                     /locus_tag="ACHBV5_001583"
     CDS             complement(75..227)
                     /locus_tag="ACHBV5_001583"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967349.1"
                     /translation="MKIKEQTRKLAAGCSKHRFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NRTTAK"
     gene            298..954
                     /locus_tag="ACHBV5_001584"
     CDS             298..954
                     /locus_tag="ACHBV5_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFM9967350.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTLVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            944..1267
                     /locus_tag="ACHBV5_001585"
     CDS             944..1267
                     /locus_tag="ACHBV5_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFM9967351.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKHKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1370..2200
                     /locus_tag="ACHBV5_001586"
     CDS             1370..2200
                     /locus_tag="ACHBV5_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM9967352.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2354..3208
                     /locus_tag="ACHBV5_001587"
     CDS             2354..3208
                     /locus_tag="ACHBV5_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFM9967353.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3308..4681
                     /locus_tag="ACHBV5_001588"
     CDS             3308..4681
                     /locus_tag="ACHBV5_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HFM9967354.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4674..5735
                     /locus_tag="ACHBV5_001589"
     CDS             4674..5735
                     /locus_tag="ACHBV5_001589"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFM9967355.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            5737..6429
                     /locus_tag="ACHBV5_001590"
     CDS             5737..6429
                     /locus_tag="ACHBV5_001590"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFM9967356.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAIPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6458..7027)
                     /locus_tag="ACHBV5_001591"
     CDS             complement(6458..7027)
                     /locus_tag="ACHBV5_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFM9967357.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7162..7776
                     /locus_tag="ACHBV5_001592"
     CDS             7162..7776
                     /locus_tag="ACHBV5_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFM9967358.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7754..9424
                     /locus_tag="ACHBV5_001593"
     CDS             7754..9424
                     /locus_tag="ACHBV5_001593"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFM9967359.1"
                     /translation="MKNWRQNRMKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HIGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQ
                     ASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9436..10722
                     /locus_tag="ACHBV5_001594"
     CDS             9436..10722
                     /locus_tag="ACHBV5_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFM9967360.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10774..11307
                     /locus_tag="ACHBV5_001595"
     CDS             10774..11307
                     /locus_tag="ACHBV5_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9967361.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11385..11855
                     /gene="nrdI"
                     /locus_tag="ACHBV5_001596"
     CDS             11385..11855
                     /gene="nrdI"
                     /locus_tag="ACHBV5_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFM9967362.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12148..13410)
                     /locus_tag="ACHBV5_001597"
     CDS             complement(12148..13410)
                     /locus_tag="ACHBV5_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HFM9967363.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIIIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13720..14178)
                     /locus_tag="ACHBV5_001598"
     CDS             complement(13720..14178)
                     /locus_tag="ACHBV5_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HFM9967364.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14175..14615)
                     /locus_tag="ACHBV5_001599"
     CDS             complement(14175..14615)
                     /locus_tag="ACHBV5_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HFM9967365.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            15048..15914
                     /locus_tag="ACHBV5_001600"
     CDS             15048..15914
                     /locus_tag="ACHBV5_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM9967366.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLNALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            16067..16195
                     /locus_tag="ACHBV5_001601"
     CDS             16067..16195
                     /locus_tag="ACHBV5_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967367.1"
                     /translation="MRSLFKKIVAVLVIGLILLGIARTPQVHKMARGIDPGPANFI"
     gene            16251..16808
                     /locus_tag="ACHBV5_001602"
     CDS             16251..16808
                     /locus_tag="ACHBV5_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavoprotein"
                     /protein_id="HFM9967368.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            17029..18135
                     /locus_tag="ACHBV5_001603"
     CDS             17029..18135
                     /locus_tag="ACHBV5_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HFM9967369.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
BASE COUNT         5565 a         3167 c         4021 g         5449 t
ORIGIN      
        1 aatagtccat gctgtggctg gattcttttc agcctacttg tactcttcga aactctcttc
       61 aaaccacgtc agcttcactt tgccgtagta cggttactga cttcgtcagt tctatccaca
      121 acctcaaaac agtgttttga gctgacttcg tcagttctat ccacaacctc aaaacggtgt
      181 tttgagcaac ctgcggctag tttcctagtt tgctctttga ttttcattga gtattattaa
      241 gacaatatga ggagaaagat gaaagaaaaa ggattttagg agggggcgca ggcagccatg
      301 ccaacggctc ttggctatgt cagtatcggc ctggcctgtg gaattatcgg tgcgccctat
      361 gtgacacttg ttgagatggg cttgatgagt ctctttgttt atgctgggag tgcccagttt
      421 gccatgttgg cactgattgt ggttcaagct cctgtggcag ctattgctat gacggttttt
      481 ctaatcaact tgcgtctctt tttgttgagt ttacacgcat cgacttattt ccgtcatacc
      541 agtctttggt acaatatcgg tatgtctagt atcttgacag atgagaccta tggcgttttg
      601 atgggtgaat tggcccatac agacaaggta aatcctatgt ggatgcacgg gaacaatctc
      661 aacagctatg tggcttggtt tgtggggaca gtagtcggaa cggctctggg tggcctgcta
      721 ccaaatccag aaatctttgg cttggatttt gccctggttg ggatgtttat tggtattttt
      781 gcttcgcaat ttcagattat gcaaagacgg attcctgtcc gcaatctgct cattatccta
      841 gcagttgttg cggtgtcctt ctttttgctc ttgacagtgg tgtctcagtc actagctgtt
      901 ctgtttgcga cgctacttgg ttgtagcatg ggggtggttt tagatggtca gtaagtatct
      961 tttattagca gttattttct ctggtcttgt gacctggatt ccccgtatga ttcccttcat
     1021 cttggtcaag cataagggcc tgcctgcgat tgttgagcgt tttttgaagt ttttgcctgt
     1081 ttccattatc tttgccttga ttctttcaag cgtagtgaca ggtaaggttg ggagccttcc
     1141 tcaaattaaa tggctagact tcttagccgt ctttccaaca gcttgggtag cctttcgcta
     1201 ccgcaatcta gtcggaacag ttctctttgg agtggtcttg attgccatct tgcgtttggt
     1261 cttttaaatt acccataaaa aaacttatca cagagataga tatcatataa tggcgtaaat
     1321 gctctttttc tgttaagatt ataaggtatt ctattttgga ggaaatgaca tgaaaaaaat
     1381 cgttaaatac tcatctcttg cagcccttgc tcttgttgct gcaggtgtgc ttgcggcttg
     1441 ctcaggtggt gctaagaaag aaggacaagc agctagcaag aaagaaatca tcgttgcaac
     1501 caatggatca ccaaagccat ttatctatga agaaaatggc gaattgactg gttatgagat
     1561 tgaagtcgtt cgcgctatct ttaaagattc tgacaaatat aatgtcaagt ttgaaaagac
     1621 agaatggtca ggtgtctttg ctggtcttga tgctgaccgt tacaatatgg ctgtcaacaa
     1681 tcttagctac actaaagaac gtgcggagaa atacctctat gccgcaccaa ttgcccaaaa
     1741 tcctaatgtc cttgtagtga agaaagatga ctctagtatc aagtctctcg atgatatcgg
     1801 tggaaaatcg acggaagtcg ttcaagccac tacatcagct aagcagttag aagcatacaa
     1861 cgctgaacac acggacaacc caactatcct taactatact aaggcagatt tccaacaaat
     1921 catggtacgt ttgagcgatg gacaatttga ctacaagatt tttgataaaa tcggtgttga
     1981 aacagtgatc aagaaccaag gtttggacaa cttgaaagtt atcgaacttc caagcgacca
     2041 acaaccgtac gtttacccac ttcttgctca gggtcaagat gagttgaaat catttgtaga
     2101 caaacgcatt aaagaactct acaaagacgg aacgcttgaa aaattgtcta aacaattctt
     2161 cggagacact tatctaccgg cagaagctga tattaaataa tttcttgaaa tcatccattc
     2221 tgagtaagat gggtggtttc tcagttttta gggatatagt tttaaactat atatctgact
     2281 atctaataac aatttgtgaa atcaaacaaa ttgtgagata ctagtacggt attattttta
     2341 aggagaaaga atcatgaaaa tcaaaaaatg gcttggccta gcagcccttg ctacagtcgc
     2401 aggtttggct cttgcagctt gcggaaactc agaaaagaaa gcagacaatg caacaactat
     2461 caaaatcgca actgttaacc gtagcggttc tgaagaaaaa cgttgggaca aaatccaaga
     2521 attggttaaa aaagacggaa ttaccttgga atttacagag ttcacagact actcacaacc
     2581 aaacaaagca actgctgatg gcgaagtaga tttgaacgct ttccaacact ataacttctt
     2641 gaacaactgg aacaaagaaa acggaaaaga ccttgtagcg attgcagata cttacatctc
     2701 tccaatccgc ctttactcag gtttgaatgg aagtgccaac aagtacacta aagtagaaga
     2761 catcccagca aacggagaaa tcgctgtacc gaatgacgct acaaacgaaa gccgtgcgct
     2821 ttacttgctt caatcagctg gcttgattaa attggatgtt tctggaactg ctcttgcaac
     2881 agttgccaac atcaaagaaa atccaaagaa cttgaaaatc actgaattgg acgctagcca
     2941 aacagctcgt tcattgtcat cagttgacgc tgccgttgta aacaatacct tcgttacaga
     3001 agcaaaattg gactacaaga aagcactttt caaagaacaa gctgatgaaa actcaaaaca
     3061 atggtacaac atcattgttg cgaaaaaaga ttgggaaaca tcacctaagg ctgatgctat
     3121 caagaaagta atcgcagctt accacacaga tgacgtgaaa aaagttatcg aagaatcatc
     3181 agatggtttg gatcaaccag tttggtaata agaaacaggg aggtgggaga gaaaattcca
     3241 cctcttgctt ttgtatagag tatagattgt aaagaagact attcgttcat agaaaggtag
     3301 agagaatatg gtttttccta gcgaacaaga acagattgaa aaatttgaaa aggatcatgt
     3361 agtccaacat tattttgagg ttttgcgtac cttgatttct aagaaatcag tctttgccca
     3421 gcaggttgga ctcaaggaag tcgcaaatta tctgggtgag attttcaagc gtgttggagc
     3481 tgaagtggag attgatgaga gctatacagc gccctttgtc atggcacatt tcaagagttc
     3541 gcgtccagat gccaagacct tgattttcta taaccactat gacactgtgc cagcggatgg
     3601 ggatcaggtc tggacagagg atccttttac gctttcggtc cgcaatggct tcatgtatgg
     3661 gcgtggggtt gatgacgaca agggtcatat cacagctcgc ttgagtgctt tgagaaaata
     3721 tatgcagcac catgatgatt tacctgtcaa tatcagcttt atcatggagg gagcggagga
     3781 atcggcttca acagacctag ataagtattt ggaaaagcat gcagacaaac tccgtggggc
     3841 ggatttgttg gtctgggaac aagggaccaa aaatgccttg gaacagctgg aaatttctgg
     3901 tggcaataag gggattgtga cctttgatgc caaggtaaaa agcgctgatg tggatatcca
     3961 ctcgagttat ggtggtgttg tggaatcagc tccttggtat ctcctccaag ccttacagtc
     4021 tcttcgtgct gcggatggcc gtatcttggt tgaaggcttg tacgaagaag tacaagagcc
     4081 caatgaacga gaaatggcct tgctagaaac ttatggtcaa cgaaacccag aggaagttag
     4141 tcggatttat ggattggagt tgcctctctt acaggaggag cggatggcct ttctaaaacg
     4201 tttctttttc gagccagcgc ttaatatcga aggaatccag tctggttatc aaggtcaggg
     4261 tgttaagact attttacctg cagaagccag tgccaagcta gaggttcgtc tggttccggg
     4321 cctagaaccg catgatgttc tggaaaaaat tcggaaacag ctagacaaaa atggctttga
     4381 taaggtagaa ttatactata ccttgggaga gatgagctat cgaagcgata tgagcgcacc
     4441 agccattctc aatgtgatcg agttggccaa gaaattctat ccacagggcg tttcagtctt
     4501 gccgacgaca gcggggacag gacctatgca tacggtcttt gatgccctag aggtaccaat
     4561 ggttgcattc ggtctaggaa atgccaatag ccgagaccac ggtggagatg aaaatgtgcg
     4621 aatcgctgat tattacaccc atatcgaatt agtagaggag ctgattagaa gctatgagta
     4681 gagatattat caagttagat cagatcgatg tgacttttca ccaaaagaag agaaccatta
     4741 cagcggttaa ggatgtgacc attcacatcc aagaagggga tatctacgga atcgttggat
     4801 attctggagc aggaaaatca acccttgtac gggtgattaa tctcttgcaa aaaccatctg
     4861 cagggaaaat taccattgac gacgatgtga tttttgacgg caaggtgacc ttgacggcag
     4921 agcagttgcg tcgtaaacgt caagatatcg gaatgatttt ccagcatttt aacctgatga
     4981 gccaaaagac agcagaggag aatgtagcct ttgcccttaa acactctgaa ctcagcaagg
     5041 aagaaaagaa ggctaaagta gctaagttgt tggacttggt tggtttggca gatcgtgctg
     5101 aaaactaccc ttcacaacta tctggagggc aaaaacagcg tgtggcaatt gcgcgtgcct
     5161 tggccaatga tccaaaaatc ttgatttcag acgagtcaac ttctgccctt gatccgaaga
     5221 caaccaagca gattttggcc ttgttgcaag atttgaacca aaaattaggc ttgactgttg
     5281 tcttgattac gcatgaaatg cagattgtca aagacattgc caaccgtgtg gcggttatgc
     5341 aggatgggca tttgattgaa gagggtagtg tgcttgaaat cttctcagac cctaaacaac
     5401 ctttgactca agactttatc tcaacagcca caggtattga cgaagccatg gtcaaaatcg
     5461 agaagcaaga aatcgtggaa cacttgtctg aaaacagtct cttggtgcaa ctcaagtacg
     5521 ctggatcttc aacagacgag ccacttttga atgaattgta caagcattat caagtaatgg
     5581 ctaatattct ctatgggaat atcgaaatcc tcgatggtac tcctgttgga gaattggtgg
     5641 tggtcttgtc aggtgaaaaa gcagcgttgg caggtgccca agaagccatt cgtcaagcag
     5701 gcgtacagtt aaaagtattg aagggaggac agtaagatgg aatcattgat tcaaacctat
     5761 ttgccaaatg tctataagat gggttggtct ggtcaggcag gctggggaac agctatctac
     5821 ctaaccctct atatgacagt tctttccttc attatcggag gcttcttggg gctagtggca
     5881 ggtctctttc tcgtcttgac agcgccaggt ggtgtcttgg agaataaagt cgtattctgg
     5941 attttagaca aaattacctc aatttttcgt gcgattccct ttatcatcct cttggcaatc
     6001 ttgtcaccac tttctcactt gattgttaaa acaagtatcg ggccaaatgc agcccttgtc
     6061 ccactttctt ttgcagtctt tgccttcttt gcccgtcagg tgcaggttgt cttggctgaa
     6121 ttggatggcg gtgtcattga ggcggctcaa gcgagcggag cgactttctg ggacatcgtg
     6181 ggtgtttacc tatcagaagg tcttccagat ttgatccgtg tgacgactgt gaccttgatt
     6241 tcccttgttg gggaaacagc tatggccggt gcggttggag ctggtggtat cggtaacgta
     6301 gccatcgctt atggatttaa ccgctacaat cacgatgtga ccatcttggc aaccattatt
     6361 atcattttga ttatctttgc aatccaattc ttgggagatt tcttgactaa gaaattgagt
     6421 cataaataaa aagagccgcg tggctctttt taactgatca gattttctgt gcaaattttt
     6481 tactcaaggc ttgtccaatc aaggcaccca ctagggctcc gatgacaata cttgcgataa
     6541 atagaaggac agttccaggg tttggagcga ccatgatacg gtcgatatat tcttgggatt
     6601 ttcctcttgc cagaagagta gccatatagg ctttgggcgc aatccacata agcaagattg
     6661 gtcctgttgt actaaaggcg aaaataatga aagaaaggaa gttctttgtt ttgtccttgt
     6721 attttcctaa atgagctact tcatctgcta ggaggccaca gataattcca ggaaggaagg
     6781 aaccagcacc gtgtttagtt cccaagaaaa agagggcaat gacaaggccg atagtggtaa
     6841 tggctccaaa gcgcggaact tttgcgacta ggatcatata gacgctaccg ccgacaaggg
     6901 cagtaaaggc aggcgcataa aacatgtttc cagtttggtc aaagagattg cccaaaagga
     6961 caccaatccc catgcagagg aagtaaagaa ctgcaaaaag cagtgtagtt aagatagatt
     7021 tcttcatgaa ttgtctcctg ataatttttt cacaattctc attgtaccac ggtttggtgg
     7081 gattgtaaat ggatactaga agtttttgaa aacgcttgaa atatgatata atggtttcat
     7141 agttattttt aggggaatat catgggtaga tttttagact ttgtctttaa tcgtttcttt
     7201 ttagggatga ttgcgacagc cttcttttgg ctattaactt tagcaggagg gattatcctt
     7261 ggtctagcgc cggctagtgc caccttgatg agcttatatg cagaacatgg ttatagcttt
     7321 cgggaataca gtttgaagga ggcttggtct ctttacaagc aaaattttgt ctcaagcaac
     7381 ctgattttct atagcttttt aggtgtgggt ctagttttga cctatggttt gtatctcttg
     7441 gtgcaattgc ctcatcagac cattgttcat ttgattgcga cccttttgaa tgtcctagta
     7501 gttgccctga tctttttggc ttatacagta tctttaaaat tacaagttta ttttgccttg
     7561 tcctatcgaa atagtctcaa attatccttg attggcatct ttatgagtct agcagctgtg
     7621 gccaagattc tccttgggac tgtgctactt gtagcaattg gttattatat gcctgccctg
     7681 ctattttttg taggaattgg gatgtggcat ttctttatca gtgatatgtt ggaacctgtc
     7741 tatgaaatca tccatgaaaa attggcgaca aaatagaatg aagcagtttt ggctacatac
     7801 gcttctaaga acctatagtt cagtgatgat cattatcatt gcgagttttg caatcttact
     7861 ctcttacgct gactgggatt cacgtgaaaa ggaagcccag agagtagccc agcgtgtaac
     7921 tgctagaaca gtgagtgaaa ttgaatatta ccatagagag tcaacccaga tagctcaggc
     7981 tttagttgaa aaccaagctc gtattgaggg aatctataaa tactttagtc ttagcatgcc
     8041 agactatttt tactggcaat tagagcggaa agcttcgcct tatatatcag tctctctgta
     8101 tgaaaatgtt gatgacctct atgttcgaaa tgattttgta actggagtgg ccattgcttt
     8161 tcaagattac aaggaagtct atgtttctac taaagacaaa cgtagtggag aaaaaatcag
     8221 ggctgaggat ttcaaaccag caggaaatag ttttgccatt ccggtgtcag atccagtgtc
     8281 agatcaagat ttaggagtga tttacatctc cttggatcct gctgttttat accatgccat
     8341 tgataatact agaggtcata ctccgatggc agtaacagtg acctcacctt ttgatacgga
     8401 gatttttcat attggtgaga cagttgataa ggagagtgaa aattggctag ttggcttaac
     8461 ttctcatgga tatcaggttc aggtggcagt tcctaaaaac tttgttttac aaggaacagt
     8521 gactagctct gctttgattg tgggtttgag ccttctcttt attgtcattc tttatctgac
     8581 tttgaggcag acttttgcta attaccaaaa gcaggtagtg gatttagtag aatccattca
     8641 agtcattgct caaggcgaag aggggcgtcg gattgacatt tccgagaaag atcaggaatt
     8701 actcctaatc gcggagacga ccaatgatat gttggatcga ttggaaaaga atatccatga
     8761 tatttaccag ttagagctta gtcaaaaaga tgccaatatg cgagccttgc aggcgcaaat
     8821 caatcctcat tttatgtata atacgctgga gttcttgcgc atgtatgcag ttatgcagag
     8881 tcaagatgag ttggcagata tcatttatga attcagtagt ctcttgcgta acaatatttc
     8941 cgacgaaaga gagaccctcc tcaaacagga attagaattt tgccgtaaat acagctatct
     9001 ctgcatggtt cgctatccca agtccattgc ctatggtttc aagatagatc cagagttaga
     9061 gaatatgaag attcccaagt ttaccttgca accgctggta gaaaactatt tcgcgcatgg
     9121 tgttgaccac aggcggacag ataatgtgat tagcatcaag gctcttaaac aggatggttt
     9181 tgtggaaatt ttggtggtcg ataatggtag aggaatgtcg gctgaaaagt tggcaaatat
     9241 ccgagaaaaa ttaagtcaga gatattttga acaccaagcc agctacagtg atcaaaggca
     9301 gtctatcggg attgtcaatg tacacgagcg ttttgtgctc tattttggag accgctatgc
     9361 cattactata gagtctgcag agcaagccgg tgttcagtat cgtattacaa ttcaagatga
     9421 gtagaaaggg agaaaatgta taaagtatta ttagtagatg atgagtacat ggtgacagaa
     9481 ggtctgaagc gtttgattcc ctttgataag tgggatatgg aggttgtcgc aacagccagt
     9541 catgccgatg aagctctaga atatgttcag gaaaatcctg tcgatgtcat catttccgat
     9601 gtcaatatgc cagacaaaac agggcttgat atgattcggg agatgaaaga gatcttacca
     9661 gatgctgcct atatcctgct ctcaggttat caggagtttg attatgtaaa aagagcaatg
     9721 aaccttagtg tggtggacta tttggtcaag cctgttgata aggtagagct gggaaatctg
     9781 ctggagaaga ttgcaggtca gctcggcgag agagggaaga aaagtcagac tcttagtcaa
     9841 gaattagacg aggctggatt tgttagttat ttaggggata aggagaattg gtggataggt
     9901 ctatccaagg aaaaacaagg ttccttcacc attccctact atgtcttggg tcaagactgg
     9961 cagattttca tttctggcca acccttagat ggcttagtcg ttactccctt tgaagctccc
    10021 tatcaagaac actttgaacg ctggaagctg aatgctgaga aaaccctctt ttacggttct
    10081 gtaaatctgc agcagtctga gagtctcttt gcctattacg aaccgattta tagggttatc
    10141 attcagggaa atctcaatca aatcgtagaa gagttaaatc tcttggagaa ggtagttctt
    10201 gaaaatacgc cgcgtgttcc gattactaaa cagcttttta ttcagtttgt catggatgtt
    10261 ttccatttat ttgaacatct caaagctgat gacctgacag acatcgttaa aaccattcat
    10321 gctattcaat ccttcgatga attggttcct tatatcaagg aaactctgac cagctttttc
    10381 ggtcaatacc gtatgaatga aaatgtggtc agtgtgctgg aagtcattgg tcgtgattac
    10441 caaaaagagc tttccctcaa ggatatcagt aaggctctct ttatcaatcc tgtctatcta
    10501 gggcagttga ttaagcgtga aaccgattcg acttttgcag agttactaaa caaacaacgt
    10561 attaaggctg cccagcagct cttgctttca actagtgaca gcatcgaaga tatttgttat
    10621 gctgttggtt acagtaacct tggatatttc tataaagttt tccgaaaatt gtgcggaaaa
    10681 tcgccaaaag cctaccgaaa acaggtagaa actatactat aagatttgta ttcctttaca
    10741 aaatgtgcta taatattatc aggaggttct atcatgaaaa agaaaccaat ttatctatgg
    10801 gtcttgctaa tcttgtctgc ccttatttca gttccgtctc tgtttggaat tgtgagtccc
    10861 ttgcctagta aagaagccct tcgtgctgct cagaaacaag ttgcaggggt caatgctcag
    10921 caattagaag accagcttaa ttatacctat agagtagcag aagcatctca ttctattttt
    10981 aatgttgctt tgattgtgct atctactatt ttagtggtcg tagcgattgt cttccttgtt
    11041 cgtaaaaatt tgcaatatgc aaactatact tacgttggct atgttttgtt agctattatt
    11101 ggttcgattt atggctatgt tggtttacaa gatgctgtgc agttggttca agatgagagc
    11161 atgcgtttga cagtgagtat tggttcaaaa gctgttagca ttttctatat cgtcatcaat
    11221 gttctcttcc tagcccttgt cttctataag atgtggcgac aacagaaagc cttggcagaa
    11281 gaagaggaaa cagaagagct tgcctaagta ttgacaaaaa agaactatca agatacaatc
    11341 ttggtagttg ttttttgatt atagataaaa tcatggaggt acatatgaag acaatttctt
    11401 tagtttatat tagtttgagt ggcaacactg aaagttttgt gacgcgcttg aaagactatc
    11461 tcttgtccca gtacaaaggg attgaggttc aaaagattca tatcaaggat ttggtcaagg
    11521 aaggcaaaaa tttctacgaa atggaccatc cctatgttgc ttttttgccg acctatctcg
    11581 aaggtgggaa tggcgtggat aacggagatg ttgagatttt gacgacaccg gtgggagatt
    11641 ttattgccta tggtaacaat gctagtaagt gttttggtgt ggttgggtca ggaaatcgta
    11701 actttaataa ccaatactgc ctaacagcca agcaatacag tcaacgcttt ggctttcctg
    11761 tattggctga ctttgaaatg cgaggcatgc tggaagatat caaacatgtc gcagctatta
    11821 tcgcagattt gtatgagttg gaaaaggaga attaatactc aatgaaaatc aaagagcaaa
    11881 ctaggaagct agtcgcaggt tgctcaaagc acagctttga ggttgcagat agagctgacg
    11941 tggtttgaag agattctcga atagtataaa gttcttataa gaggtggttg aagttgttca
    12001 actgtttttt gagtataaac agtctttaag aacgtaaaaa agcataagtt caggtcttca
    12061 aaaccttgtt cttatgcttt ttatcataga aatatttgct gaattttctc ttgaaatgaa
    12121 accttatctt catctcgcgc ttgtccctta ccctgctttt ccgattgcga gtgcgtagat
    12181 aaagaagatg gcgaagccaa agaggaaaat caatcccgca atggcaaggt gtttgagcca
    12241 agaaggaaga tttttgtttt cacgtgttac caaggcgtaa ttcaaaagag caaagaaagg
    12301 tgttgtcagg aaagagccaa tcatggcaaa gcggagcatg gttgaaacct gaccagcgaa
    12361 gaacttgata atgatgatac cgatgatagc agtgatggtc atccagatgt tcaaagattt
    12421 acgattatcc tctttttgac tgattagcag tcggagagat tcctgattaa cgcgagaata
    12481 gccatcgata acagttataa ctgttccaaa gatacagagg aaggcaataa aggtaatcaa
    12541 gtaacgggac cattcgccaa gaacagaggc atacatgccc acgaattgag agatgtattt
    12601 ggctgaagca gcttcaaccg cctgccctgt aggatactga atcagtgctc ccagtgccac
    12661 aaagaagacg gctaggatag ctgttccaat ataaccagtg ttaaagtcaa acagagcgtc
    12721 ttctgtgtta aagttgacgg tctttctctt ttcagctgac caaagtgaat tgatggctga
    12781 aatttcaata ggagccggca tccatcctag gagggagacg atgaagggca gagctgccat
    12841 ttgccaaggt gtcttctcga caaaatcaga actgtattct ggatgcttga ccgccgcaat
    12901 gataactgca agaacagtcg caatggttaa ggcagacata atccatttga ccatgccgtc
    12961 taaaagtttg tagcctccaa agagtagcat agcccaaatg attgcaacga gaatgaggga
    13021 ccactgagta atgctaagtc caatcattgg gaaggcactg gcgatgatag ctgagcacag
    13081 aatggcaaca ccagccgtgt tgaccatagc cgaaaagaca ttgaggataa agaaaatcca
    13141 gagatagagt tttccttttt cggcataacc ttcaaccaaa gtctttccag tatcagctgt
    13201 gtattcagca ccaaaacgga aaaatggata tttaaagaca ttggctaaga tgaccaagag
    13261 aagtagagac caaccgtaag aaccgccagc ttgagttgag gatacaatgt gggaacctcc
    13321 aacagcggca gttgccatta ggattccagg tcccattgct tttagcttgc ttgcccaggt
    13381 tgattgattt aaggaaatag cttgcgacat gataaatact cctttttgaa ttttcagaat
    13441 aatctgtata tgtaatctat attctacaaa aaattttgga aaaatgcaag agtattttga
    13501 aaaaagatag aaaatttaca aagaaaatct gaaataactg ttatgatata gaggattgaa
    13561 actagaatag tacacctctg cttctaaaac attgttagaa atcgatttga ctgtcctgat
    13621 cgatttatcc tgttcttatt tcatttcact atagtaaggt gcagcaggat aaagaaaaac
    13681 cgagaagttt ctttctcgga tttgcttatt atgaggttcc tattttctat gctccaagag
    13741 ttgattgatg tgatctactt ttttagcctc tcttttatag agaatagccc agatgatgag
    13801 atagacaatc gcaaactcga taatgagctg gaggtagaaa atccagtgga aagggaacca
    13861 accagcaaga gttgctagtg ggacaaagcc agccagcata aggaagaaat gagtcagagt
    13921 ggcacgaagc atgctccagt cacggctaaa taagcggttg ccaaagttga agagcatacc
    13981 gatggttgcc cagataagtg tgcagtagag caagaccagg gcaccgtgaa cctgatgctg
    14041 atccatcact tggccgatga gagagtaggg atttagtggt gcgtaggtat ttggtgcata
    14101 aatgagtgaa aagaggatag agaggatgag gccgataaga acaccggtag ctgcatcgtg
    14161 aaatacttgt tttttcatag ttctaatttc tccttgatgg tttttagata acggcgtgaa
    14221 gagtaggtga agctttcgtt tttcaagaaa atttctacca gaccgtttgg cgtgagcttg
    14281 aggtgagaga tggaatcgat attgatgatt tctgattggg aaatttggat aaaattggtt
    14341 ggcaagagtt taagaacctg atagagtcgc aaatcaatgc tgtaggtctg actcgcggtt
    14401 tctgctagaa ccttccgatt ctcgatatag aagcgctgaa tcttgccaat ctcaactaga
    14461 tagacctgat catcgatttt tcctttgatt ttttctcttt ggtccagatt ttctgcgaac
    14521 tcgatgactt tctggacttt ttcggtttct tgaggtgctt ggacaatcag cttttcctcc
    14581 tcgtaagtct cactaatctg tagttctact ttcatagttt tctctccttt tcagttatac
    14641 aaggttgtga tcacttcctg tatatcctta ttaaacacta ttttatagcc catggcaagg
    14701 aaccttgtct atgtggaggg attgggctcc tatgtggtgg agcttttctg ttctttctga
    14761 aatatggtat aatagcacta atcaatttct aggaaaatag atacggaaag gggctgaaag
    14821 aactagggga acagttggaa ttagaaagtg ataggtatga aaagtggcgt tgaagctgaa
    14881 taagtttata aagcgtttga atgaagaaat ggaaagtaaa taagttgacg atgaattaca
    14941 aaatagattt tatctacaat ttgtatcttt caaatcattg atttgaattt tagatttaat
    15001 catgttacaa ttaaaactga aatcaaatag aagaggaaaa tgcaaacgtg ggcacactat
    15061 tagcaacaag attaaaaaat agacggaaag aattaaaaat gtctcagcga gaactagctg
    15121 aaggtatctg taaacagggg caaatcagtc gattagagag cggagagttt acccctggag
    15181 cggatttcct gaatgccctt gctaagaagt taaaagtcag tatggattat ttttttgatg
    15241 agcaggttgt agagaaagtt gaggagttat cagaatttaa gaaattagca cagacattta
    15301 ttacaaatcg caattatgag tctttgaaat atatatatga attggagaat gtaaaagctc
    15361 accgcctatc tttagcagat aaaatctaca tggaatggat aaaatctctg atagattttt
    15421 atttttacgg acagaaagaa gatgcgattg tacgattaga gggggtatta tcacagttaa
    15481 gtgtatctga tttgaactat ctccaagttt caaacaccct attcaatttt tattatgata
    15541 ttggagattt aggtcgtttc aataaaattc gtgaaaaact agagtatcaa gtaaatcacc
    15601 tcaatttgag tacaatcgaa gagttagaac tatctattaa gtttaactac aacgtttgtc
    15661 gttatctatg gttacagaaa aatattgaag aagctattac taaaattaca gctactataa
    15721 aacaatgtaa ggcttacaga acgaattatc ttttggctga tttgtactta ttgatgggaa
    15781 atgtaagtga aaatttttct tctaaaagtt cggtgaaaga atattttgag acggcatatt
    15841 ttctatacaa acttgaggag aacatgtcaa tgactctgaa agttgagcat tacattgcag
    15901 atataacaga ataatgaata cggtgttcaa gtgagcatcg tttttcaaac ctagttcaga
    15961 tacaaaaaag tatcaaacaa aaaaaaataa aaaaacatta taaaaacaat tgacaagcta
    16021 attttgaagt gataaaataa atgcaagaaa acaaaaggag aggtatatga gaagtttgtt
    16081 taagaaaata gttgctgtat tagttattgg cttaattctg ttaggaattg cgagaacacc
    16141 tcaagttcat aagatggcta gagggattga tcctggtcct gcgaatttta tttagaaatc
    16201 aatttctact aattgagtac taattgagta ttaatgggta aaaagattgt atggataaga
    16261 aaaatttact tgtattggtt actggttcgg taggtgccag taatgtagat acatacttat
    16321 attatataaa aaaattctat aatgttaaag tgatactttc tgaaaattct aaaaaattta
    16381 taagtaagga attaattagt tatttttgtg ataaagttta tgatgaaata tttgttgaag
    16441 aggtagttcc gcacgttttt ctgccatatg aatctgactt acttcttatt ttaccagcta
    16501 cggcaaatgt gattggcaaa attgctaatg gtattgctga tgatttagtt acagcaactg
    16561 ttttaaactt taataaaaaa ataatttttt gtcccaatat gaactctact atgtgggaca
    16621 atcacatagt tcaaagaaat gtatcaattc taaaggagtt gggacatata tttttatttg
    16681 agtctaaaaa aacatatgag gtaggattgc gtaaagcaat agattcaaca tgttcaatgt
    16741 tacaaccaca gtcgttagta aaagaactta tcaaattaga aaatattgtc cttgaagagg
    16801 gacattaaaa actactgaga atattaagga ggggaaaaaa tggaaaattc atcaatcgat
    16861 gtagatatgc tgttggaaga attgacacaa gaagcaatgg tcgttgttgc tgttgataag
    16921 gactgttaat ttaaacttat ggcaatatat gaaaggttac tggatgtttt aaattatgca
    16981 ggcagtagcc ttttattata tacaaatgga taaagtaagg ataatacaat gattaataaa
    17041 aaaatacaac aagttgtttt ggaatcatta cagaattttt tgaatgggaa cttcatttcg
    17101 ccttgtgtag tctatgattt tggcttgctg gaaactgtac ttgatgaatt taaaaatcaa
    17161 attcctgtaa cattcaatta ccaacttttt tatgccgtta aagcaaattc aaatgagaag
    17221 atacttgaat tcttagtaga taaaattgat ggagttgatg tggcgtcatt atctgaatta
    17281 gatgtggcta aaaaattttt cccaccaact caaatttctg ttaatggtcc cgcattttct
    17341 tatgaaactt tatataatct gattaaaaaa caatataaag ttgatattaa ctttttggaa
    17401 catcttcaac aattttcccc aaaagaatct gttggaataa gagtaacgga gccagatgaa
    17461 cttaataatc gtatgagtcg atttggaata aatatttgca gtgataattg gactagtaat
    17521 ttacaaaatc ctttaattac acgactgcat tttcattttg gagaaaaaga tgataaattt
    17581 attgttaagt tagataaaat attatttaag ttacaagaaa ttaataaact tagagaggtt
    17641 agagaaataa atcttggagg cggttttatg aaattattta tggaaaatcg tttgaaagaa
    17701 ttttttctat cacttatgga aatctataaa aagtacgata ttgatagtac tgtgactaca
    17761 ataatagaac caggtagtgc aattacttca ttttctgcct atatgattac tagcccagtt
    17821 aatgttagtg aggtgaatga gcagcaggtt atcacgttag acacatcaat atacaccaat
    17881 acattatggt ttgttccgca tattattaca acgttaaatt caagtagtaa agagcgttat
    17941 agtactattc tctatggtaa tacctgttat gaacatgaca agtataaaat gaaagtttcg
    18001 cttccaaggt taactcaaaa tagcagtata gtgttttttc ctgtaggagc ttatataaaa
    18061 agcaatcatt caaatttaca tcgtaatgat tttatgcggg aggtatattt gtggacaaaa
    18121 aacttgacat attagataaa gttaaggaat atttaggaaa taaaactact caaattctgg
    18181 ataatcaata taaagaattt tt
//
LOCUS       DAYYYC010000045        18146 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.045, whole genome shotgun sequence.
ACCESSION   DAYYYC010000045 DAYYYC010000000
VERSION     DAYYYC010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18146
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.045"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(141..1076)
                     /gene="birA"
                     /locus_tag="ACHBV5_001604"
     CDS             complement(141..1076)
                     /gene="birA"
                     /locus_tag="ACHBV5_001604"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HFM9967370.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1073..1933)
                     /locus_tag="ACHBV5_001605"
     CDS             complement(1073..1933)
                     /locus_tag="ACHBV5_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFM9967371.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2041..4203
                     /locus_tag="ACHBV5_001606"
     CDS             2041..4203
                     /locus_tag="ACHBV5_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFM9967372.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4295..5554
                     /locus_tag="ACHBV5_001607"
     CDS             4295..5554
                     /locus_tag="ACHBV5_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFM9967373.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5568..6434
                     /locus_tag="ACHBV5_001608"
     CDS             5568..6434
                     /locus_tag="ACHBV5_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM9967374.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTRWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6448..7281
                     /locus_tag="ACHBV5_001609"
     CDS             6448..7281
                     /locus_tag="ACHBV5_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM9967375.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKLTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7288..7428
                     /locus_tag="ACHBV5_001610"
     CDS             7288..7428
                     /locus_tag="ACHBV5_001610"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967376.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKVKLTWFEEI
                     FE"
     gene            7639..9081
                     /gene="gtfA"
                     /locus_tag="ACHBV5_001611"
     CDS             7639..9081
                     /gene="gtfA"
                     /locus_tag="ACHBV5_001611"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HFM9967377.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRSVVKALLNLFSFRNRSEAFDLEGTIEIETPTVHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9219..10412
                     /locus_tag="ACHBV5_001612"
     CDS             9219..10412
                     /locus_tag="ACHBV5_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HFM9967378.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11099..13078
                     /locus_tag="ACHBV5_001613"
     CDS             11099..13078
                     /locus_tag="ACHBV5_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM9967379.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13145..14641
                     /locus_tag="ACHBV5_001614"
     CDS             13145..14641
                     /locus_tag="ACHBV5_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9967380.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14641..15567
                     /gene="oppC"
                     /locus_tag="ACHBV5_001615"
     CDS             14641..15567
                     /gene="oppC"
                     /locus_tag="ACHBV5_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HFM9967381.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15576..16643
                     /locus_tag="ACHBV5_001616"
     CDS             15576..16643
                     /locus_tag="ACHBV5_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9967382.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16654..17580
                     /locus_tag="ACHBV5_001617"
     CDS             16654..17580
                     /locus_tag="ACHBV5_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFM9967383.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
     gene            complement(17655..>18146)
                     /locus_tag="ACHBV5_001618"
     CDS             complement(17655..>18146)
                     /locus_tag="ACHBV5_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM9967384.1"
                     /translation="HRKSHEHKAIKHYWKLIQQDSRKLSDKQFYRPTFRMHLTNKEIL
                     NKLLSYSEDLKHHYQLYQLLLFHFQNKEPEKFFELIEDNLKQVHPIFQTVFKTFLKDK
                     EKIINALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVL
                     SRA"
BASE COUNT         5342 a         3216 c         3812 g         5776 t
ORIGIN      
        1 aaaaataggc tccataatat ctatagggga tttacccact acaaatatta tagagacaat
       61 aaaacttcag atccgtaaaa cttaattgaa ttactaatct gaagttattt ttatatcgtt
      121 tatattataa ttgtgttatt ttacttccaa ctattgagag aaatttcgcc actatttagc
      181 cagatttctt ttccgttatc acattgaact aaaagttttc cattttctga gatgtcttta
      241 gcaagtccct tgtagtcttt ttgctctagt gtgaaagtga cttcttttcc tagaatgaat
      301 gactgttttt tgtataggta taatagctct tctgctggtg tttcgaagaa agcacgccag
      361 atttctatga tcaattcatt ccttgttata ggagctgtag ctttaaataa gctggcagct
      421 ttttctttta attcctgagg gaagtcttta atagtgaaat tgatacctac tccaataatg
      481 atatctgtga ctaagccagt ttctacagag gtcattgctt cagtaaggat tcctccaatt
      541 ttatgattgt ttagatagat atcattgacc cattttatgt cgacatctat taaagttagg
      601 ttcttaatgg ctttgtagac agctccagct acaagtagtg tgtaggatgg taatttgtca
      661 taggggagat ttggtttaag atggagtgtc atataaatac caccttgtgg tgagtagaag
      721 gaacgttgaa aacggcctcg gcctgctgtt tgataggaag ctagatagag ggtatttgct
      781 tcatggccta aatcaattgc ttcttttgca tctagttgtg ttgattttgt ttcgggttta
      841 aagctgactt taattggaag attttcttct agaatctctg gaagaataag gtcaccattc
      901 atcagtttat atcctctatt tttgatacta tcaatttcaa tgccttcttg ttctagtcgc
      961 ttgatggctt tccaaattgc tgttcggctt agggatagtt tttctgcgat tttttctccg
     1021 ctgatatagt cggtttcttt agataggatt tggtagacag cttggtagga tttcataatg
     1081 ttgcctttct tactagttgg tattgagagt attcttttct tgtatgactt ggagtctgat
     1141 taaagtattg tttataagct ttcgaaaaat ggagtggatc tgaaaaacct accgagtatg
     1201 caattacctt gatggactct tgggtatttt cgagaagttg tctagctcgg tgcattcgaa
     1261 cgtagagtag gtattctttg ggtgataagg tattaaattc tttgaatacg cttgataagt
     1321 agcttctgtg aacggatagt tcttttgcta aatcttgaat tgtaagtgat tgaggatagt
     1381 ggctatcaat taatcgtttg cattcaagat agagttggtg ggttgatgaa atattctttt
     1441 ttttctgatt gggagcaata gttcccagat gaaacatcag ttcatgaagt tgtcccatga
     1501 tatggagttg agctaattca cttgattttg taatctgagc gaagcggaca atgtctgaga
     1561 tgagttttgc agtagtctgg gtatgacaag tttcagattg gatgagatag gattgatcag
     1621 aaatttggga aagagcaaaa taatcagggg ctttccctcc agtgattcct aaccagtagt
     1681 aggcccaagg ttctttacta tctgcttgat aaaaggttag ttcctctggt tttaatagaa
     1741 agaaatctcc ttcttttaaa tcaacaattt tacccttgta atgaaatttt ccttgtcctt
     1801 tagtaatgta atgtaggacg tatgtatcac gaatggctgg accaaaagag taattaggtg
     1861 tgcattcctc atatccataa aagcttaggg caaggtcgat tgttccagtc tggtattctg
     1921 aaaaaactaa catgtgctac ctcctaccta acattttacc atattcttga gacatttttc
     1981 tattttggaa agcgatttca ggtgataaaa tagagtcaat aaagtgatga ggtgaagtaa
     2041 atgggagtta ggatagagaa taatctattt tatgttgaga gtaaaaatct aagtttgatt
     2101 attgaaaatc gaaatggcta cttacttttg aaacatttag gaaagactat taagaactat
     2161 aaaggttcca atagtgttta tgaacgagac catgcctttt caggaaatcc aacagctact
     2221 aatcgaacct ttagtttaga tactcaacgt caaatttttg gacaacatgg cttaggagat
     2281 tttaggaaac caaccataca ggttcagcat aatgtaactg aagtaacaga ctttcgattt
     2341 gtagaagcaa agattttaaa aggtcagaat ggtccacagg gcttaccttc tccacatagc
     2401 atggacgata cagagactct tgtcttaatg ttagaagatt ctaaggctca acttagtctg
     2461 actttgtatt atactacttt taataatgat gcgactattg ctagctacag taaattagat
     2521 aataatagta atcaggaagt tgtcatccat aaagattttt cttttatggc tgattttcca
     2581 gctgcagatt acgaaatagt aactctgcag ggtgcttatg ctcgtgaaaa gactgttaga
     2641 cgtcaacagg tagaacaagg aatcttttcg attagttcaa accgaggtgc ttctggtcat
     2701 gctcaaacac cagctcttct actatgcgaa caaggagtca cagaggatgc tgggaatgtg
     2761 tttgctattc aactaatgta tagtggcaac tttgaagctt ttgttcaaaa aaatcaattg
     2821 aatgaagttc gggtggctat tggcattaat ccagaaaact tttcttggaa gttagcccct
     2881 gaggaatact ttgaaacacc ggtagcttta gtgactcatt cagatcaggg attaactggt
     2941 attagtcatg aaagtcagaa ttttgtactg aagcacatta tgctaagtga attttctaaa
     3001 aaagaacgtc caattctaat caataactgg gaagctactt actttgactt tcagagagaa
     3061 aaactgttag agttagcaga tgaagctaag aaagttggca ttgaactttt tgtattagat
     3121 gatggttggt ttggcaatcg ttttgatgat aatcgtgctt taggtgattg ggttgttaat
     3181 gaggaaaaac tgggtggaag tctagaaagt ctgatttcag ctatccatga aagaggtttg
     3241 cagtttggac tttggttaga acccgaaatg atttctgtag atagtgattt gtatcgtcaa
     3301 catcctgact gggctattca ggttcctggc tatgagcata cttattctcg gaatcaatta
     3361 gtacttaatc ttgccaatcc tcaggtagta gaatacttga aaagtgtctt agatcaactc
     3421 ctatcttatc atgagattga ttacattaaa tgggatatga accgcaatat cactaagcta
     3481 gggaatggat taacttatct agagacacag atgcaatctc atcagtacat gctggggctt
     3541 tatgaactcg tttcttatct gacagagaag cacagccata ttctctttga gtcctgctct
     3601 ggtggtggtg gacgaaatga tcttggtatg atacgctatt tcccacaagt ctgggctagt
     3661 gataatactg atgccattgc acgtttacca attcaatacg gttcatccta tttctatcca
     3721 accatttcta tgggggctca tgtgtcagca gtaccgaatc atcagatggg acgaatgaca
     3781 ccattagaaa cacgtggcca tgtagcaatg atgggaaatt tgggctatga gcttgatttg
     3841 acaaatttat cagatgaaga gaaagctacg attgctaatc aggtgaactt gtataaagaa
     3901 ttacgaccag tagttcagtt aggacagcag tatagactaa ttaatcctga tactgcatcc
     3961 aatgaagcag ctgtacaatt taattacgga aatcaaacga ttgtaaccta cgttcgcgtt
     4021 ttatctgttg tagagaccat ggaaacaact ttaaaattaa aagatttgga tgaagaggga
     4081 ctatataaat tacaggaaaa tggcgaagtt tactcaggtg cagaactaat gtatgcgggc
     4141 ttaactgtta tcttatccca aggagatttt ttgagtagac agtatatttt tagaaaacta
     4201 tgatatgtac tgaccccaaa agttagattt attctgtcta acttttgggg tgcagttcaa
     4261 taagggtgta taaatttata aaggaggctt tctaatggaa tggtataaaa aaatcggact
     4321 tcttgcaact acaggtttag ctttgtttgg gctcggcgct tgctccaact atggtaaatc
     4381 tgcggatggc acagtgacca tcgagtattt caaccagaaa aaagaaatga ccaaaacctt
     4441 ggaagaaatc actcgtgatt ttgagaagga aaaccctaag atcaaggtca aagtcgtcaa
     4501 tgtaccaaat gctggtgaag tattgaagac acgcgttctc gcaggagatg tgcctgatgt
     4561 ggtcaatatt tacccacagt ccattgaact gcaagaatgg gcaaaagcag gtgtttttga
     4621 agatttgagc aacaaagact acctgaaacg cgtgaaaaat ggctacgctg aaaaatatgc
     4681 tgtaaacgaa aaagtttaca acgttccttt tacagctaat gcttatggaa tttactacaa
     4741 caaagataaa ttcgaagaac tgggcttgaa ggttcctgaa acctgggatg aatttgaaca
     4801 gttagtcaaa gatatcgttg ctaaaggaca aacaccattt ggaattgcag gtgcagatgc
     4861 ttggacactc aatggttaca atcaattagc ctttgcgaca gcaacaggtg gaggaaaaga
     4921 agcaaatcaa taccttcgtt attctcaacc aaatgccatt aaattgtcgg atccgattat
     4981 gaaagatgat atcaaggtca tggacatcct tcgcatcaat ggctctaagc aaaagaactg
     5041 ggaaggtgct ggctataccg atgttatcgg agccttcgca cgtggggatg tcctcatgac
     5101 accaaatggg tcttgggcga tcacagcgat taatgaacaa aaaccgaact ttaagattgg
     5161 gaccttcatg attccaggaa aagaaaaagg acaaagctta accgttggtg cgggagactt
     5221 ggcatggtct atctcagcca ccaccaaaca tccaaaagaa gccaatgcct ttgtggaata
     5281 tatgacccgt ccagaagtca tgcaaaaata ctacgatgtg gacggatctc caacagcgat
     5341 cgaaggggtc aaacaagcag gagaagattc accgcttgct ggtatgaccg aatatgcctt
     5401 tacggatcgt cacttggtct ggttgcaaca atactggacc agtgaagcag acttccatac
     5461 cttgaccatg aactatgtct tgaccggtga taaacaaggc atggtcaatg atttgaatgc
     5521 cttctttaac ccgatgaaag cggatgtgga ttaggagtag agagactatg aaaaaagtat
     5581 tacaaaaata ttgggcatgg gcttttgtgg tcatccccct cttgttacaa gcaattttct
     5641 tctatgtgcc gatgtttcaa ggagcctttt acagttttac caactggaca ggattgactt
     5701 acaactacaa atttgtcggc ttaaacaact ttaagctcct cttcatggat ccaaaattca
     5761 tgaatgcgat tggctttacc gcaatcatta cgattgccat ggtggttggt gagattgcac
     5821 tcgggatctt cattgcgcgt gtcttgaact ctaaaatcaa aggccaaacc ttcttccgtg
     5881 cttggttctt cttcccagct gttttatctg gtttgacagt ggctttgatc ttcaagcaag
     5941 tcttcaacta cggtcttcca gcgattggga atgcccttca tattgaattt ctccaaacca
     6001 gtcttttagg gactaggtgg ggagcaatct ttgcggctgt ctttgtcctt ctttggcaag
     6061 gggtggctat gcccatcatc atcttcctag ctggtttgca atctattcca actgagatta
     6121 cagaggcagc aaggattgat ggtgcgacta gcaagcaagt tttctggaac attgaattgc
     6181 cttacttgct accaagtgtc tctatagtct ttatcctagc cctaaaaggt gggctgactg
     6241 cctttgacca agtctttgcc atgaccggtg gtggtccaaa caatgccaca acctcacttg
     6301 ggctcttggt ttataactat gcctttaaaa acaaccaatt cggttatgcc aatgccattg
     6361 ccgtaatctt gttcttctta attgtagtga tttcgatcat ccaattgaga gtatctaaga
     6421 aatttgaaat ttaagaggag aagcatgatg aaacaagatg aaagaaaagc cctgattggc
     6481 aaatacattc tattgattct aggatcggtt ctgattttag tgccgctcct tgctaccctc
     6541 tttagttcct tcaaactcac taaggatatt gtagataatt tctttggctt tccaaccaac
     6601 ttcacatggg acaactttag ccgtctctta gctgatggga ttggaggcta ttattggaac
     6661 tctgtcgtca tcactgtctt gtctttactt gcagtaatga tctttatccc tatggcagcc
     6721 tactccatcg ctcgcaatat gagtaaaaga aaagccttta ccatcatgta taccctctta
     6781 atcctcggaa tcttcgtacc tttccaagtc atcatgattc cgattacggt tatgatgagt
     6841 aaactcggtt tggctaatac ctttggtttg atcttgctct acttgaccta tgcgattcca
     6901 cagaccctct ttctctatgt tggctatatc aaaatctcga ttccagaaag tctggatgaa
     6961 gcagcagaga tcgatggggc taatcaattt acaacctatt tccgcatcat cttcccaatg
     7021 atgaaaccga tgcatgcgac aaccatgatc atcaatgccc tttggttctg gaatgacttc
     7081 atgttgccac tccttgtctt gaaccgggat tccaaaatgt ggactctgcc tttgttccaa
     7141 tacaactacg caggccaata tttcaacgac tacggaccaa gctttgcctc ttacgtggtc
     7201 ggcattatca gtatcaccat tgtctatctc ttcttccaac gccatatcat ttcaggaatg
     7261 agcaacgggg cagtgaagta atactcaatg aaaatcaaag agcaaactag gaagctagcc
     7321 gcaggttgct caaaacactg ttttgaggtt gtggatgaaa ctgacgaagt cagtaaccat
     7381 acctacggta aggtgaagct gacgtggttt gaagagattt tcgaatagta taagaagagc
     7441 tcatggaatc tatagtcttt gacacagagg aagagttcag cttgttgata attctatgta
     7501 gaaaacaaga aagtagtact ttgtttatca cagtctatat tagtacgagt ttgatgataa
     7561 atagagattt aaaatgaatt ttatttatga agccagatca tatgagactt ggcttcaatt
     7621 agaaaaagga gagtaatgat gccaattcaa aataaaacca tgttgattac ctattctgat
     7681 agccttggaa ataatcttaa agacttatat gataatttgg aagagcattt tggagatgct
     7741 attggaggag ttcacctttt accatttttc ccatcaacag gtgatcgtgg atttgcgcca
     7801 gttgactacg acgaagtgga ctcagctttt ggtgattggg aggatgttaa gcgtttaggt
     7861 gagagatatt atcttatgtt tgattttatg attaatcata tttctcgtca atccaagtat
     7921 tataaggact atcaagaaaa acatgaagcc agtgaattta aagatctctt tttaaactgg
     7981 gataagtttt ggccagaaaa ccgtccgaca cagtctgatg tagatttaat ttacaagcgt
     8041 aaggatcgtg caccaaagca agagattgtg tttgaagatg gttcagtgga acatttgtgg
     8101 aatacctttg gtgaggagca gattgatctt gatgtgacca aagaagtaac tatggaattt
     8161 atccgtaaga ccattcagca cttggcaagt aatgggtgtg atttgattcg tctagatgcc
     8221 tttgcttatg cagtgaagaa attggatact aatgatttct ttgtggaacc agatatttgg
     8281 gatttattgg acaaagttcg agatatcgct gctgagtatg ggacagagct tttacctgag
     8341 attcatgaac actattcgat tcagtttaaa atagcagacc atgattacta tgtttatgat
     8401 tttgctcttc caatggtgac actttatact ctttacagtt ccagaacaga gcgtttggct
     8461 aagtggttaa agatgagccc gatgaagcaa tttacgacgc tagataccca tgatgggatt
     8521 ggagtagtag atgtcaagga tatcctgacc gatgaggaga ttgactatgc ttcaaatgaa
     8581 ctctataagg ttggagccaa tgtcaaacgt aagtactcta gtgccgagta taacaactta
     8641 gatatctacc aaatcaattc aacctactat tcagcgcttg gagatgatga tgtcaagtat
     8701 tttctcgctc gtctaattca agcttttgcc ccaggtattc ctcaggttta ctatgtgggt
     8761 ctattagcag gcaagaatga cttgaaatta ttagaagaaa ctaaagaagg tcgaaatatt
     8821 aatcgtcatt actatagcaa cgaggaaata gcaaaagaag tgcaacgatc tgttgtgaag
     8881 gcccttctca atctattttc tttccgtaac cgttcagaag cctttgatct agaagggact
     8941 attgagatag agacaccaac agttcacagc attgtaatca aacgtcaaaa taaagataag
     9001 tccgtaacag cagtagcaga aattgatttg caaaatcaga cttatcgggt aattgagaat
     9061 ggagttgaag taacattttg aagccttgat atggtggata aaatagggtt tttattttgg
     9121 aaaacgtttc ctttgttttc aaattgctaa aaaagtggta caatatagga tagcttacta
     9181 ttatctgaat cagctgattt ggagagaaag gattcatttt gaaatcaata ggctttattg
     9241 aaaagctgaa ggggttgtct agtaaagagc tgattttatt gggaattatc ctaagtatct
     9301 ttttaccctt ttatcttttt gtagttgtac tctgtttata tattatcagt ttgattttta
     9361 caggagacat gaaaagtatt cttcagaaaa tgggggagca tccgatgctg cttctttttc
     9421 ttagctatag tactgttata tccattcttg cacaaaattg gatgggtctt gtggcttcag
     9481 taggaatgtt tctatttact attttctttt tgcactatca gtcgatttta tcccataaat
     9541 tctttcgatt gattttgcag ttcgtcttgt ttggtagtgt cttgtcagct gcttttgcca
     9601 gtttagaaca tttccaaatt gtgaagaaat ttaactatgc ttttctttca cccaatatgc
     9661 aggtgtggca tcagaaccgg gcagaagtga ctttctttaa tcctaattat tatggaatta
     9721 tttgttgttt ctgtattatg attgctttct atctgtttac aacgaccaag ttgaattggt
     9781 tgaaagtatt ctgtgtgatt gcaggctttg ttaatctctt tggtttgaac tttactcaaa
     9841 atcgaactgc ctttcctgct attatcgctg gagcaattat ctatctcttt acgactatta
     9901 aaaactggaa ggccttttgg cttagtattg gggtcttcgc gattggtttg agtttcctct
     9961 tttctagtga tttgggagtt cgaatgggta ctttagactc ttctatggaa gaacgcattt
    10021 ctatctggga tgctgggatg gccttgttta agcaaaatcc tttttggggt gaagggccat
    10081 tgacctatat gcactcttat cctcggatac atgctcctta tcatgaacat gcccacagtc
    10141 tttatattga tacgattctg agttacggaa ttgtgggtac cattttatta gttttgtctt
    10201 ctgttgctcc tgttcgcttg atgatggata tgagtcagga gtcggggaaa cgtccgatta
    10261 tcggccttta tctatctttc cttacagtgg ttgctgtgca cggaattttt gacttggctc
    10321 tcttctggat tcagtcaggc tttattttct tgctagttat gtgcagtatt ccattggagc
    10381 atcgaatgtt ggtatcggac atgacggatt aagttttata agtttgaaat cttctacctt
    10441 gggtaggaga tttttttata cgatgggcat gtcgtgcatc tgaggtgtaa gtcctctgta
    10501 gggatccact accggtgaat acaatagcgc tccccaagcc tgactatcgt gaggtagcgg
    10561 attaaaatgg tctggggata gatcgtttta agtctgacgc aggaaataag aattgtcaga
    10621 gaaagcaata gtgaaatcgt aggctatgaa tagaaacgtg atagcgagga gcatatagtg
    10681 gataaggtag cgagaaattt taaagtataa aagatagtct taatctatat atgtaaatca
    10741 caaaagtaat tgaattcgga ataaggttgg tgtgaaaaga catagtaaac tgaatcttga
    10801 atactagaat gatacttcta caatattgtt ataatttaat ttgaattcca aaatcacatt
    10861 gttccgtccg tatttcattt tactgtatgt cttcctaaac tccaaagttt ctgcgtcaaa
    10921 tttcctattt tcactgtagt ctttgacact tcgaacgaca atttgaatca tatattcaaa
    10981 aaaaaatgaa aaatttgtgc caacaagcct aaatattctg aaaatttgtt tgatttttaa
    11041 tggataatgt gatataatgg ttgtcaatct ataattcaca taaacagagg agtagaaaat
    11101 gaaaaaaaat cgtgtatttg ctacagcagg tcttgtttta ttagcagcag gtgtacttgc
    11161 agcatgcagt tcttcaaaat catctgattc atcagcccct aaagcttatg gctatgttta
    11221 tacagcagac ccagaaacct tggactacct gatttcaagt aaaaatagta caacagtagt
    11281 gacttcaaat gggattgatg gtttattcac taacgataat tacggtaatc ttgctcctgc
    11341 agttgcagag gattgggaag tctctaagga tggtttgacc tacacttata agattcgtaa
    11401 aggggttaaa tggtttacct ctgatggaga agaatatgca gaggtgacgg ctaaagattt
    11461 cgtgaacggt ttaaaacacg cagcagataa aaaatcagaa gctatgtatt tagctgaaaa
    11521 ttcggttaaa ggcttggcag attatctatc aggaacttca acagattttt caacagttgg
    11581 tgtcaaggcg gttgatgatt atacgttaca atacactttg aaccagcctg aaccgttctg
    11641 gaactctaag ttgacctatt ctattttctg gcctctgaat gaagaattcg aaacatcaaa
    11701 aggaagcgat tttgctaaac caacagatcc gacatccttg ctttataatg gtccattctt
    11761 gttgaaaggg ttgactgcaa aatcttctgt agagtttgta aaaaatgagc aatattggga
    11821 taaagaaaat gtccacctag atactatcaa tctagcttac tatgatggat cagatcagga
    11881 gtcgctagag cgtaacttca ctagtggagc ttatagttat gcccgtcttt accctaccag
    11941 ctccaactat tctaaggttg cagaagaata caaggacaat atctattaca cacaatcagg
    12001 ctctgggatt gctggtctgg gtgtgaatat tgatcgccaa agttacaact atacttctaa
    12061 aactacagat tcagagaaag tagctactaa gaaggcattg cttaacaaag atttccgtca
    12121 agccttgaat tttgctcttg atcgctcagc ttactcagct caaatcaatg gtaaagatgg
    12181 agcagcttta gcagttcgta atttatttgt aaaaccagac tttgtttcag ctggtgagaa
    12241 gacctttggt gatttagtcg ctgctcaact tcctgcttat ggtgatgagt ggaaaggtgt
    12301 gaatttagct gatgggcagg atggtttatt caatgctgac aaggccaagg cagagtttgc
    12361 gaaagctaag aaagctttag aagcagacgg cgttcagttt cctattcatc tggacgttcc
    12421 agtagaccaa gcatcaaaaa actacatatc tcgtattcag tcctttaaac aatctgtaga
    12481 aacagttctt ggtgttgaaa atgtcgttgt tgatattcaa caaatgacaa gtgatgaatt
    12541 ccttaatatt acttactatg ctgccaatgc ttcatctgag gattgggatg tatcaggagg
    12601 agtttcatgg gggccagact atcaagaccc atctacttac ctggatattt taaaaacaac
    12661 tagcagtgaa actacaaaaa catatttagg atttgataat ccaaatagcc cttcagtagt
    12721 tcaagttggt ttgaaagaat acgataaatt agttgatgaa gctgccaaag agacaagcga
    12781 cttgaatgtc cgttatgaaa aatatgcagc ggctcaagca tggttgacag atagttcact
    12841 ctttattcct gctatggctt cttctggtgc agcaccagtg ctttcacgaa ttgttccatt
    12901 tactggagct tctgcgcaaa caggctctaa ggggtcagat gtttacttca aatatttgaa
    12961 attacaagat aaagtggtga ctaaggaaga gtatgaaaaa gctcgtgaaa aatggttgaa
    13021 agaaaaagct gaatcaaatg agaaagctca aaaagaattg gcaagtcatg tgaagtaaat
    13081 aatttctaat agaactttct ctccatgagg agaaggttct tttgggattt ttaaaggaaa
    13141 taatatgaaa aaatatattt ttatgcgtgt tttgcggtca ttggtttcga ttttcttagt
    13201 aacgactttg acctacacga ttatctatac cttggttcct cgaaaattga ttttcaagca
    13261 ggatcctaac tataataaaa ttgcgacaac ggctgataaa cgtgataact atgaaaatac
    13321 tgtgtttgag cgtatgggct acattgagta ttacgatact aaagagttgc aagaaaaggc
    13381 aagtagcatg gattcttctg taacagtaga agcaaatgcg accaataaag ctatttatga
    13441 aaagtacatc aatcaattag gtcatggttg gactttggga gaatttactg aaagtggtca
    13501 attctatgct actcgtgaaa ttccaatttt tgaacgtgtt tttcacttct atgctaactt
    13561 gattgacatt gaccatacaa ataaaatcca agaccctgaa aatccagact tgaaacgcta
    13621 ccttcgtttt gaaaatgatc cagctatcgg atggtcattg gtcggttcag gaactaaaca
    13681 taaatatctc ttgtacttta acagtcagtt cccatttgtt catcaaaact ttgtgaactt
    13741 gaatttaggt gactcttacc caacctatgc taatacacca gttcttcagg ttattactca
    13801 aggtcaagga caaaccaaaa ctgcccaagt tcagttccca acaggtaaga aaacgtcttc
    13861 tgtaaatatt tactcaagaa cctacaagtc acctagtcag gctgactctc gtgaagtagc
    13921 tagctatggg aaagatgatc cttatacagc gactgaaagt aattaccaat atccatctat
    13981 gattgtcagc tctgctatta ctggtttgat tggtttggtt cttgcctatg ctcttgccgt
    14041 gccacttggt tcagccatgg ctcgtttcaa gaacacttgg attgatagcc tctcaacagg
    14101 gactttgacc ttcttgcttg ctcttccaac gattgccttg gtttacatcg ttcgattgat
    14161 tggatcatct attgcccttc cagattcatt ccctatcttg ggagctggag attggcgttc
    14221 ttacgtttta ccagcagtca tccttggttt attgggtgct cctgttacag ccatttggat
    14281 tcgtcgttac atgattgact tgcaatctca agactttgtt cgtttcgctc gtgcaaaagg
    14341 tttgtctgaa aaagaaattt caaacaaaca catctttaaa aatgccatgg ttccgctggt
    14401 ttcaggaatt cctggtgcca ttattggggt tatcggtggt gcaaccctta ctgaaacagt
    14461 cttcgccttc ccaggtatgg gtaaaatgtt gattgactct gtaaaagcat ctaataactc
    14521 tatggtcgtt ggtcttgtct tcatctttac atgtatttct atcttctcac gtcttttggg
    14581 agatatttgg atgactatta ttgacccacg tattaaattg actgagaaag gaggcaaata
    14641 atgtctacaa tcgataaaga aaaatttcag tttgtaaaac gtgacgattt tgcctctgaa
    14701 actattgatg cgccagcata ttcttactgg aaatcagtgt ttaaacaatt tatgaagaaa
    14761 aaatcaactg tagtcatgtt gggaatcttg gtagccatca ttttgataag tttcatctac
    14821 ccaatgtttt ctaagtttga tttcaatgat gtcagcaagg taaacgactt tagtgttcgt
    14881 tatatcaagc caaatgcgga gcattggttc ggtactgaca gtaacggtaa atcgctcttt
    14941 gacggtgtct ggttcggagc tcgtaactcc atcctcattt ctgtgattgc gacagtgatt
    15001 aacttggtta tcggtgtttt tgtcggtggt atttggggta tttcaaaatc agttgaccgt
    15061 gtcatgatgg aagtttacaa cgtcatctca aacatcccac ctcttttgat tgttattgtc
    15121 ttgacttact caatcggagc tggattctgg aatctgattt ttgccatgag cgtaacaaca
    15181 tggattggta ttgccttcat gattcgtgtg caaatcttgc gctatcgtga cttggaatac
    15241 aacttggcgt cacgtacttt gggaacacca accttgaaga ttgttgccaa aaatatcatg
    15301 cctcaattgg tatctgttat tgtgacaacc atgactcaaa tgcttccaag ctttatctca
    15361 tacgaagcct tcttgtcttt cttcggtctt ggattaccga ttacagtgcc aagtttgggt
    15421 cgtttgattt cggattattc acaaaacgta acaaccaatg cttacttgtt ctggattcca
    15481 ttgacaaccc ttgtcttggt atccttgtcc cttttcgtag ttggtcaaaa cttagcggat
    15541 gctagtgatc cacgtacaca tagataggag tagaaatgac aaaagaaaaa aatgtaattt
    15601 tgactgctcg cgatattgtc gtggaatttg acgttcgtga caaagtattg acagccattc
    15661 gcggcgtttc ccttgaacta gtcgaaggag aagtattagc cttggtaggt gagtcaggat
    15721 caggtaaatc tgttttgaca aagaccttca caggtatgct cgaagaaaat ggtcgtattg
    15781 cccaaggtag tattgactac cgtggtcagg acttgacagc tttatcttct cacaaggatt
    15841 gggaacaaat tcgtggtgct aagattgcga ctatcttcca ggacccaatg actagtttgg
    15901 accccattaa aacaattggt agtcagatta cagaagttat tgtaaaacac caaggaaaaa
    15961 cagctaaaga agcgaaagaa ttggccattg actacatgaa taaggttggc attccagacg
    16021 cagatagacg ttttaatgaa tacccattcc aatattctgg aggaatgcgt caacgtatcg
    16081 ttattgcgat tgcccttgcc tgccgacctg atgtcttgat ctgtgatgag ccaacaactg
    16141 ccttggatgt aactattcaa gctcagatta ttgatttgct aaaatcttta caaaacgagt
    16201 atcatttcac aacaatcttt attacccacg accttggtgt ggtggcaagt attgcggata
    16261 aggtagcggt tatgtatgca ggagaaatcg ttgagtatgg aacggttgag gaagtcttct
    16321 atgaccctcg ccatccatat acatggagtc tcttgtctag cttgcctcag cttgctgatg
    16381 ataaagggga tctttactca atcccaggaa cacctccgtc actttatact gacctgaaag
    16441 gggatgcttt tgccttgcgt tctgactacg caatgcagat tgacttcgaa caaaaagctc
    16501 ctcaattctc agtatcagag acacattggg ctaaaacttg gcttcttcat gaggatgctc
    16561 caaaagtaga aaaaccagct gtgattgcaa atctccatga taagattcgt gaaaaaatgg
    16621 gatttgccca tctggctgac taggaggaag gaaatgtctg aaaaattagt agaaatcaaa
    16681 gatttagaaa tttccttcgg tgaaggaagt aagaagtttg tcgcggttaa aaatgctaac
    16741 ttctttatca acaagggaga aactttctcg cttgtaggtg agtccggtag tgggaaaaca
    16801 actattggtc gtgctatcat cggtctaaat gatacaagta atggagatat catttttgat
    16861 ggtcaaaaga ttaatggtaa gaaatcgcgt gaacaagctg cggaattgat tcgtcgaatc
    16921 cagatgattt tccaagaccc tgccgcaagt ttgaatgaac gtgcgactgt tgattatatt
    16981 atttctgaag gtctttacaa tcaccgttta tttaaggatg aagaagaacg taaagagaaa
    17041 gttcaaaata ttatccgtga agtaggtctt cttgctgagc acttgactcg ttaccctcat
    17101 gaattctcag gcggtcaacg tcaacgtatc ggtattgccc gtgccttggt catgcaacca
    17161 gactttgtta ttgcagatga gccaatttca gccttggacg tttctgtacg tgcccaagtc
    17221 ttgaacttgc tcaaaaaatt ccaaaaagag ctcggcctga cctatctctt catcgcccat
    17281 gacttgtcgg ttgttcgctt tatttcagat cgtatcgcag ttatttacaa gggtgttatt
    17341 gtagaggttg cagaaacaga agaattgttt aacaatccaa ttcacccata tactcaagcc
    17401 ttgctttcag cggtaccaat cccagatcca atcttggaac gtaagaaggt cttgaaggtt
    17461 tacgacccaa gtcaacacga ctatgagact gataagccgt ctatggtaga aatccgtcca
    17521 ggtcactatg tttgggcgaa ccaaaccgaa ttggcacgtt atcaaaaagg actaaactag
    17581 taatggtttt ataatttcca tgtcaatttt tatggaaatt aggctctttg tcaactgtag
    17641 tgggttgaag tcagctaagc tcgagaaagg acaaatttcg tcctttcttt tttgatgttc
    17701 aaagcgataa aaatccgttt tttgaagttt tcaaagtttc gaaaaccaaa agcattgcgc
    17761 ttgataagtt tgatgagatt attggtcgct tccagtttgg cattagaata gtgtagttga
    17821 agggcgttga taatcttttc tttatctttg aggaaggttt taaagacagt ctgaaaaata
    17881 ggatgaacct gcttaagatt gtcctcgata agttcgaaaa atttctctgg ttccttattc
    17941 tggaagtgaa aaagcaagag ctgatagagc tgatagtggt gtttcaagtc ttccgaataa
    18001 ctcaaaagct tgtttaaaat ctctttattg gttaagtgca tacgaaaagt aggacgataa
    18061 aattgcttat cactcagttt acggctatcc tgttgtatga gcttccagta gtgcttgata
    18121 gccttgtgtt catgggattt tcgatg
//
LOCUS       DAYYYC010000046        17726 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.046, whole genome shotgun sequence.
ACCESSION   DAYYYC010000046 DAYYYC010000000
VERSION     DAYYYC010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.046"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(117..1541)
                     /locus_tag="ACHBV5_001619"
     CDS             complement(117..1541)
                     /locus_tag="ACHBV5_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HFM9967385.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVAEKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2086..4365)
                     /gene="pulA"
                     /locus_tag="ACHBV5_001620"
     CDS             complement(2086..4365)
                     /gene="pulA"
                     /locus_tag="ACHBV5_001620"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HFM9967386.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPYGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4477..6435)
                     /gene="ligA"
                     /locus_tag="ACHBV5_001621"
     CDS             complement(4477..6435)
                     /gene="ligA"
                     /locus_tag="ACHBV5_001621"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFM9967387.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERGNLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6528..7706)
                     /locus_tag="ACHBV5_001622"
     CDS             complement(6528..7706)
                     /locus_tag="ACHBV5_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFM9967388.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGFIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSIHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7786..8649)
                     /locus_tag="ACHBV5_001623"
     CDS             complement(7786..8649)
                     /locus_tag="ACHBV5_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HFM9967389.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYFFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8652..10553)
                     /locus_tag="ACHBV5_001624"
     CDS             complement(8652..10553)
                     /locus_tag="ACHBV5_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFM9967390.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGDELDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSKKTSGNVVLTVENTAI
                     GYDGEVLSQPINVDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYIEKRATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            complement(10983..11258)
                     /locus_tag="ACHBV5_001625"
     CDS             complement(10983..11258)
                     /locus_tag="ACHBV5_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFM9967391.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(11365..12204)
                     /locus_tag="ACHBV5_001626"
     CDS             complement(11365..12204)
                     /locus_tag="ACHBV5_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFM9967392.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            12346..13194
                     /locus_tag="ACHBV5_001627"
     CDS             12346..13194
                     /locus_tag="ACHBV5_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFM9967393.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(13287..14204)
                     /locus_tag="ACHBV5_001628"
     CDS             complement(13287..14204)
                     /locus_tag="ACHBV5_001628"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HFM9967394.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            14610..14743
                     /locus_tag="ACHBV5_001629"
                     /pseudo
     CDS             14610..14743
                     /locus_tag="ACHBV5_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
     gene            complement(15068..15361)
                     /gene="rpmA"
                     /locus_tag="ACHBV5_001630"
     CDS             complement(15068..15361)
                     /gene="rpmA"
                     /locus_tag="ACHBV5_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFM9967395.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(15378..15722)
                     /locus_tag="ACHBV5_001631"
     CDS             complement(15378..15722)
                     /locus_tag="ACHBV5_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFM9967396.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(15738..16052)
                     /gene="rplU"
                     /locus_tag="ACHBV5_001632"
     CDS             complement(15738..16052)
                     /gene="rplU"
                     /locus_tag="ACHBV5_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFM9967397.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(16088..16175)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(16240..16938)
                     /locus_tag="ACHBV5_001633"
     CDS             complement(16240..16938)
                     /locus_tag="ACHBV5_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFM9967398.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     gene            17340..17639
                     /locus_tag="ACHBV5_001634"
     CDS             17340..17639
                     /locus_tag="ACHBV5_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFM9967399.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         5422 a         3765 c         3071 g         5468 t
ORIGIN      
        1 tgtactattc tagtttcaat atactataat accaaaaagt tcgtattttt tctataatta
       61 ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctgattt tacacgttat
      121 ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata tttaattcct
      181 tgcactccag ctccagaacc tttgacacca aggaatggga aattatctgg accacgctgg
      241 gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc aaaggctttt
      301 ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt ggcaaaggca
      361 atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa tggctcttcc
      421 catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag gagattgccc
      481 tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc aatcaagccc
      541 caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt gtcaaatgga
      601 tcaccaactg ttaatttaga aacttcttcc tgaagcaaag tagctaattt ctctgctaca
      661 ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta gctaaaggct
      721 cccgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac aagagctgca
      781 tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc aatacgttct
      841 ccaataggag ttgaacctgt aaagttgatg aagttgactt ctttgtgctc aatgatataa
      901 tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg aatccctgct
      961 tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg tggcttaaac
     1021 atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa attaactgga
     1081 taattaaagg gagcaatcgc tagcacgata ccaactggtt cacgacggac aacagccagt
     1141 ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt gatacggaga
     1201 ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc aattgctgct
     1261 ttaatccctt ttgctacttc tttggcaagg atagtaccaa tttcttcctt atcgcgttct
     1321 aaaatagctg ctgttttatg taaataagcc gcacgttcaa ctgctgataa agctcgccat
     1381 gctggcaggg ctgcacgcgc agcttgcata gcctcatcag cttcagtctg agtcatggct
     1441 ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc ttgttcagat
     1501 gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc ctcctgaaaa
     1561 tgattaagat atattttacc aaattttcag aaaatcacaa ccctttttgc aaaatttttg
     1621 agattatttt cacaaacttg atttttcaaa gtatactcaa taaaaataaa aaaaatccac
     1681 tacgtcaagg cgaggctaat gtggtttgaa gaaattttcg aagagcgtga atgagtatca
     1741 tctatagtaa aataaaaaaa ctgaacaatt tggttgggga cagccaaacc aatttctcac
     1801 aatgtttcag aaacaagggt gtgctactcc aatttcagcc tactataact gtcatagatt
     1861 gctgaaacaa agtctaggta aaagtcttca taataaaaag acctcctatc aagtgttcaa
     1921 aaactttgat aggaggtctt gttttgtgaa aatatttatc aaattttcta tacaagtgag
     1981 ctgttagcca ggttctttct attctttcaa tttcaatgaa tggatttttt actaatactc
     2041 ataactggga atttgtctgt gtaaaaatag cgagatagat ggtatttata aaacactcaa
     2101 gacagctaga ctaatatcat ttaaaacatt atcttctttt gagcgactgt tggttaccaa
     2161 catagctaaa tttcctgcat tttcaaattg atagggttct gatttagcat tcacaaccac
     2221 caagaggtgt tctttgccgt gaacttcata gataaggtag ccgctatgtt caatcgcaga
     2281 atgcacaaag acatgatggt aaatttcatc atagctagag taagaaaagg caccagtttt
     2341 tgtcttcaat cggatgactt gacggataaa ctcaatactg tcttgacgct cattaatcaa
     2401 gttccagttc acttggttca cactgtcagg agcattatag ctattcatcg cacgctctct
     2461 atcatcatgg gtcaactcac cattttcacc agtcgcaacc agtttggtac gaccaaattc
     2521 ttgaccgatt tccataaagg ccatcccctg catgagcaga ttcatggctg tggcagtttc
     2581 gaccttgcgc atgatttgct ctgaactttg gtctggatga agggttgcca ataaatcgtg
     2641 aagattgtaa ttgtcatggg cttctacata gttaagcacc tgatttggat gtgtatagct
     2701 tcctaattca cgacttccta ggattgcttt agctagaatt ggctctgtcg cagcaccact
     2761 gacaaaacct gacttgatag caccataaac ttctccccct ttgacagcat cgcgctgatt
     2821 gtcattaaag aaaccaatat ttggcatctg gtaggcattg tccttcttgg ccttatcata
     2881 aggggcaaga cctgttccca tatcccatcc ttctccatag aggataatgt tggagtcgat
     2941 ttcatccaag ctttgacgaa tcatctgcat ggtcttgaca tcatgaatcc ccatcaagtc
     3001 aaaacggaag ccgtcaatat tatattcctg cacccagtat agaagagaat caatcatata
     3061 cttgcgaaac atttcgtgtt cactggctgt ttcatttcca acacccgttc cattctggaa
     3121 ggtaccatat ggattcatac gataatagta atcagggact gttgtttgga atggtgcatc
     3181 aacaactgag aaggtatggt tatagactac atccataatg actccaatac ccgcatcgtg
     3241 ataagcttga accatcacct tcaaatcacg aatgacctga gctggatcat ctggattagt
     3301 tgaaaaacta gtttctggcg cgttatagtt ttgtggatca taaccccagt tgtaggttac
     3361 atttccatcc tcatcgtatt ctttatgacg gtctgcaatt ggttgcaatt gaacataatt
     3421 gtagcccagc ttcttgatgt aatcaaaagc agttgactgg ccgtattggt taactgttcc
     3481 agcctgagca gcacccaaga aagttcctcg aagatgttca tctacacccg atgtaggtga
     3541 tttagtcaaa tcacgaatat gcatttcaca gataactgcc ttacatggat tttccaagcg
     3601 ccaagtagcc tccgaaccgt gcttaacctc gaagttttca acttgctttt ctacatggct
     3661 cagaatagct gaacgtttgc catcagggct ggtcgcgatt gtataaggat cacgtgtcag
     3721 tgtttggtga tgagggaatt ggacttgata ctgataagcc ttacctacca aatcttcctc
     3781 aacatccaaa ctccagacac cgattgtatt gtccttatga ttataagagt agctattgcc
     3841 tcttttcatc tcaaaagtct tccaaacggg tgcatcatta gcagctgatt cataaacgac
     3901 aacttgcact tctgtcgctg taggtgacca gagggaaaaa tgagcctgat tgtcctctac
     3961 acggcaaccc aattctcctt ggtaacccca atgatggtca aaactagcac tgttaatggc
     4021 cttatcaaag gcaaaaggat tttgattttt atagaaagga ctggcaatag caggattttc
     4081 agagtaataa atcctatcat cgccttccaa aatccagacc tctgttaata ggggatagtg
     4141 attaaaacgg atagaatatt ctttactagt ttgacctgta tgaaccacaa aattcaagct
     4201 ttctataaca tgtgaacttg ggtgttcaaa gctaaataaa gctccaaaat aatcttcttt
     4261 gtaggttagc aaatcaattc gttgatcctg actttttaca aaggagcaag tgtcatattc
     4321 tccattctta cgatggtaat gaatgcgcat agggtagtta tacatttttt atttttcctt
     4381 tttactttgt ttctatttca ctaataaatt tttgtcaatc tcgtctcaat taacagacat
     4441 agtcatattc tctaaactct gtttttaaac gatccattac aaactttcta gccatgcctc
     4501 atctctgacc tggataccaa gttcttgtgc tttttgcagt ttacttccag cgtctgcacc
     4561 taccacgacg aggtcggtct ttttagaaac actacctgtc actttggcac ccagactttc
     4621 gagtttactt ttagcttctg agcgcttgag tcgttccaat tttcctgtca ataccacggt
     4681 caaacctgac aaggccgcat ccgctactac cgtctgtcct ttatagtcca gattgacccc
     4741 agtttctttc aattctctga gcagaatttc agagccttct gtcgcaaaat aagtctgaag
     4801 acttttggca atcacgccac ctagactttc aatactagcc acttcctctg aatctgcctg
     4861 atacagattt tcaattgaat ggaaatattg aagtaaaagc tgactagcct tgcttccgac
     4921 atgacgaatt cccaaaccaa ataagagctt ctcggcagaa ttttcctttg atgcttggat
     4981 agcctgatac agtttagcag cggacttttc cttaaccccc tctaaaagga ggaaatcctc
     5041 ttcttgcaaa cgataaatat ccgccacatc cttgactaaa ttagcagcaa aaagcttctc
     5101 aacaatagat ggaccaaggc ctgtaatatt catagcatca cgagaagcaa agtgaatcaa
     5161 gccttccatg atttgagcag ggcaacgcgg attgatacaa cgtagggcca cttcatcttc
     5221 aaagtgcaac aagtcagagt tacaacttgg acagtttgta gggatatcta gtttttcttc
     5281 agaaacccgt ttggactcta ccacacgtaa aacggcaggg atgatgtcac cagccttata
     5341 tacaatgacc gtatcgtctt ttcggatatc tttttcagca atataatcta cattgtgcag
     5401 ggtcgcacgg ctaacagtcg taccggcaag ttgtactggt gttagattag cagttggagt
     5461 tacaacaccg gtacggccaa ctgtccagtc aactgataag agttgagctt ctttttcttc
     5521 agcagggaac ttgtaggcta ctgcccactt tggagcctta acggtaaaac caagttcttc
     5581 ttgacttgct aggtcgttga ccttgattac cactccatca atatcgtaag gcagatttcc
     5641 ccgttcctgt cctacttctt ggataaaatt ccagatttca tctatgtttt cagccaagat
     5701 tcgcttagga ttgaccacaa aacctagttg ttctaggtac ttcaaaccct tttcttggct
     5761 atcacgagtt gaagggctgg cttcttgata gagaaacgtt gcaagattac gcttggcaac
     5821 tactgctgta tccaactgac gcagagttcc tgctgccgca ttacgaggat tagcaaattc
     5881 aggctctcca ttttcttggc gcacttggtt aacttggtca aaggaagcgc gtggcatgta
     5941 acattcccca cgaactgtga tatctagttc ttctggcaaa gtcaaaggga tgtccttaac
     6001 acgcttgagg ttttctgtga tattttcacc aattgaacca tctccacgtg ttaccccagc
     6061 aaccaaaatc cccttttcat aagtcagcga gatagataag ccatcgattt tcagctcaca
     6121 aatataggtc ggatgagcca cttccttacg aacacgcgca tcaaaagcat ctagctcctc
     6181 acgtgaaaaa gcatcctgca aactataaag aggatactga tgactgtatt tttcaaaacc
     6241 atctaaaacc ttgccaccaa cacgatgagt cggactgtct gctagcactt gctctggata
     6301 agcagtttct aactcgacca actcacggta aaggcggtca tactcactgt ctgaaaccga
     6361 gggattatcg ctggtatagt actcagtcgc atagcgattg agcaaagcga ctaactcatt
     6421 cattctttta ttcataagac cattttacca taaaacaagc cctcctcaca aacgagaagg
     6481 gcggaaaaaa cacttagttt gaaattattt ttgaaactca agcaacctta tatcaatttt
     6541 tcaaaatgag ttcgaacata aataaacgat atacaagaca agatgataac accacttcca
     6601 attatcagga aagaagagag atgtatactt ggcaagactg tcataaatcc ttttgcaata
     6661 ggcataaata gaatagctaa ggtaaaaatt gtactcagta ctcttccaag aaattcgctc
     6721 tcaaccttgg tttgtacttg agtaaaaaag tgaatattaa aaatcgtcat aaacaattca
     6781 caaactaaat ttccagaaaa ggaaagaaaa gttggaagtg gtaatcccat cataaaaact
     6841 ccgacacctg tcaaagccag taaaatcaaa agattataaa tattagcttt aattttacta
     6901 gctagaagag ccccaatgat gaaaccaata gcccccatag ttaaaatact tgcataggct
     6961 ccttctgacc cgtaaagctg attcgaaaag ggaagtagaa attcaaaagc tgcaaaaaag
     7021 aaattaacgc tggaagctac cagcaaaagg aagaaaattt cttgctgatg ccagatatag
     7081 tgtaacccat ccttgatatc tacaaaaata tctctcccag taaaagcctt tttctcttga
     7141 acttttgctt cctcttttgg aaggaaagcc actagaacaa aagcaatgaa aaaagtcagc
     7201 gagtctagca gtagcgtcat atggagactt gcaaactgta aaacaaggaa ggaaagaaca
     7261 ggagagctaa cacctacaac ctgcaaaacc agctctaagc gagaattata gatcacaatc
     7321 tcatctttct ccaccacttc agttatgata gctttattgg ctgtgcgaga aaaggcaaaa
     7381 gcaatagcct gcacaatgtt agcaacaatc aaagcgccaa tcatccagct atcattcctt
     7441 atgaaagaaa tagccagaca aagaatccca caaacaagat ctgccgtcat taaaatctta
     7501 cgacgagaaa aacggtctga aataactccg ccaaagggat tgacgagaat agatgtgacg
     7561 agctcagaaa tctgatacat tcctaaaact gtctgtccta tagtccccat agaagccaac
     7621 cagacactat ttccataatc atagagcata tttcccattt tattgatagc cccacggcta
     7681 atcaactgca ctgcatagcg attcatatta aagctcctct caaattttga aactattgta
     7741 tcaaaaccga aaggagcttt ttattttttc ccttatttgg gaaaattaac ttttgacaaa
     7801 tttttcgtag tgttcctgat aataggctac ttgctctgga agacctaaca catcaaaaat
     7861 atgtatggcc tcttgcatct gcttacagcc ttctttacac tgtccttttt gatataaggc
     7921 aaaacctttt aaataatgga aaacattacg ctcataaagc ttaatacctt tgtcaataat
     7981 cttctctgta taagcctcaa aatagttggc attataaaaa gaagaatgct ctaaacaatg
     8041 ctggtaacaa ttgagggcca aaatcaaaac taatctctta tggcgactaa tctcttggta
     8101 aaattcctcc ctctccataa cttctctacc aatccgagtg acatagtcta catcgtagaa
     8161 actatagagg ttaccgaaaa gaatcaactc atacatggtc cattcttctg ttttgaagaa
     8221 ataatctgct accttatcca aatcatcctg cttcatatca taactcgcat ctctttgaca
     8281 aatcagacct tgtagcaaaa tccagttcag ctcaaaataa aggggagtcg tcgaactctt
     8341 agacttttca agttgttctc tttgaagctt ttgaaaacct gcaatatcgt ttgaatagta
     8401 aagtgggata atctgtgcca tcatagacac atgttcatga ttatgaaaat tccttgcctt
     8461 atccatgaaa ttttcgattg ttacatgaat gttatccaaa atctcaaaga aacgggagac
     8521 tgccaggtca gactccccaa gctcaaagcg agataactga gaggtagagc aggattcgcc
     8581 tgctgcttcc tttaaagaat aatttccact tgttcgaaat tcacgaaata cttttccaag
     8641 atgttccatc tttacacctg atctgataat tcttcccact caagcatagc ttcttcctga
     8701 cgatggctga ttttgtccag ctcagcctgt aattccatga gtttgtcggc atcgtttgtt
     8761 tccaacattt gttcagaaat ggcttggctt tgactttcta gctcttcaat ttcagcttct
     8821 agactttcga tttgtcgcat gagtttgcga acttcttttt gactttcttt ctgggcctga
     8881 tagtcattga ctggacttgc ttcctttgct tgattgctag ttgaagcttc ctcagtctga
     8941 ctcatttctg ctgttgctct cttctcaata tagtagtcgt aatctccaag gtagagagtt
     9001 gaaccattct cagacaattc caaaacatga gttgccacac gattgataaa gtaacgatca
     9061 tgactgacaa aaagcaaggt accatcaaag tcaatcaagg cattttctag cacttcctta
     9121 ctatcaatat ccaagtggtt ggtcggctca tccagaatca aaaagttatt gttttccata
     9181 gacaatttag ctaaaagcaa acgagctttt tcgccaccag atagcatgcc gactgatttt
     9241 ttaacatcat ctcctgagaa aaggaaggct ccaagacggt tgcggatttc aacttctggt
     9301 gtcagtttga aatcattcca gagttcatcc agcaccgtat tacttggtgt cagcttgctt
     9361 tgggtttggt catagtaacc aacctcaaca ttagcgccaa agcgcttttc tcccttgata
     9421 aaaggaatct ggtccacaat agacttgata aaggttgact tgccgatacc atttggacca
     9481 acgatagcga cagcattcat cttacgaaga tctacgttaa tcggttgtga caggacttcc
     9541 ccgtcataac caatagcagt attttcaaca gtcaaaacaa cattgcccga cgttttttta
     9601 gactggaagg tcatgttggc tgctttcttg ccagcttcag gcttgtccaa acgctccatt
     9661 ttttctagtt gtttacggcg agattgagca cgtttagtcg ttgaagcacg aactagattg
     9721 cgattgacaa agtcttccag agcagcgatt tccttctgtt gcttttcata gttttttgcc
     9781 tcagtagcta gcttttgctc cttcaattcg acaaaacgag agtaattccc cacatagcga
     9841 tccaaggaat gcttggtcaa atctagcgta attgtcgcaa ccttgtccaa gaaataacgg
     9901 tcgtggctga cgataatgag ggcaccgcta tagtttacca agtaattctc tagccaggcg
     9961 atggtttcaa tatccaagtg gttagttggc tcgtccaaga ccaagagatt gggcttttca
    10021 aggagcattt tagctagagc caaacgagta ttttgaccac ctgaaagttc agctattttc
    10081 atctgccaca tagactcgtc aaacttgaat ccattcaaaa tcgctcgaat atcagcttca
    10141 taggtaaagc cgcctgcttg gcgaaaattc tcagataagt ggtcgtaatc tgacatcagt
    10201 ttatccaatt catcgccaga cttttcaccc atctccaact ccatctgacg aagttgttta
    10261 tctgtccgac gtaagtcatc aaagacatga agcatctcat catagatggt attttcagac
    10321 tcaaaacggc tatcttgagc taggtaagac agagaaatat cttttttctt attgatttct
    10381 ccactagttg gctcctcttc tccaactaaa atcttcaaaa gagtagactt acctgcacca
    10441 tttttcccaa caagggcaat ccgatctcgt tcatcaacct gcaggttgat attatcgaaa
    10501 agaacctctc ctgcaaaaga acgttcaatt ttattagctt gtaaaataat catacaagta
    10561 gtatagcatg tttccctaag tcattcaaga taatcgtaag tcttttagta caacttttat
    10621 aacataaaat aaactaaatt atgtatattt tatattagat tccttcacta tcttgttgga
    10681 ttttctaacc agctaatctt gtttcaaata gttatcgcac aagcctatta tttaattctt
    10741 ttcattattt acgtacgcgt atagcagatt gaaataagat gagaacaaat cgattgggaa
    10801 agtaaaatta atttctataa atgttttagc aattgtttcg tactatttta gattcagtct
    10861 actatatata caatattttc ggaacattca actttttaac tctatttatt actagatttc
    10921 ataattaaaa agcctactga ccaagctaga aagcttgata caataggctt tttaaagact
    10981 gattatttaa cagcgtcttt aagagcttta ccagctttga atgctggtac tttagaagct
    11041 gcaattgtca tttctttacc agtttgtggg ttgcgacctt tacgttctgc gcgctcacga
    11101 acttcaaagt taccaaaacc gatcaactga actttttcac cagctgcaag atagtcagct
    11161 actgctgcaa atacagcttc aactgctgct gctgagtctt tcttagttaa ttctgtagct
    11221 tctgctactt tagcgatcaa atcttgtttg tttgccatgt taatgattcc tccaaataat
    11281 ttctaattaa caaatataat catatcctaa aatccctttt aggtcaagtt aaaaacgcta
    11341 tttcttccca ttttatttat ttttttagga gtggtaacgt atcaaaatag cccaagcgtt
    11401 ctcacccgtg tgagtttgaa taatggaacc cgtttccaaa acagaaattg gcttttcaac
    11461 ataagcttgt aagctttctt tcatctcttt tgcccaatca tcactaccag aatatgaaat
    11521 tccaatctct gctacagcac gttcagaaag cgatgttatc aactcatcta accatttttt
    11581 aaatgtttta gttccacgac ctttaaccat tggctgcaat tcatggtctt tcatttgcat
    11641 gacaacacgg atattgagaa gagagctcaa caagccagtt acacggctaa ttcgtccacc
    11701 tttgacaaga ttttccaaag ttgaaacacc aatataaagc tctgtatggt ttttaacctc
    11761 ttctacatga gataaaattg cctccatatc tttaccttct tgagctaact tcgcagcctc
    11821 aacaacttgg aatttcaggg cttggtcagt gaaggaacta tcaacaacag tcacatctgc
    11881 agtagatagg ctagcacctt ggcgtgctgc ttctaccgta cccgaaagag catgggacat
    11941 atgaatagca agaatctggc caccatcttt gcataggtct tcaaaaatct cagcaaagac
    12001 acctacaggt ggctgacttg ttttcggaag attcttactt tcttgcatca actgaagaaa
    12061 tttaccttct tctttcaaat ccgcatcaga ataaacaaca ttatcaatca ttacagataa
    12121 tggaacaatt gtaatatcta attgctttac tagttcaggt tcaatagtaa cagatgaatc
    12181 ggttacaatc ttaatttttg tcatagtatc aatctttcta ttttaggatt cagattggtt
    12241 tccttacttc taattatatc aaaaaaaaga ttaaaaatcc taatggagtc aatcaaattt
    12301 tccgtaaaat ttgatataat caacttataa gaaaagaggt gtcctatgat taaaaaaatt
    12361 taccccattt ttaccatttt actaggtgct gctatttatg cttttggact gacttatttt
    12421 gtagttcccc atcatctctt tgaaggaggg gcgacaggca ttaccctcat caccttttat
    12481 ctttttaaaa tccctgtttc cctcatgaac ctgctgatta atattcccct tttcatccta
    12541 gcttggaaga tctttggagc caaatccctc tattctagtt tactaggaac cttagctttg
    12601 tccgcctggt tagctttttt tgagcatatt ccccttcata ttgatcttca aggtgattta
    12661 ctaatcacag cccttatagc gggaatccta ttgggaattg gccttggaat tatttttaat
    12721 gctggaggta caactggcgg aactgatatt ctagctcgta ttctcaacaa atacactcat
    12781 atatccatag gaaaactgct ctttatctta gatttttgta ttctcatgtt gattctccta
    12841 atcttcaagg atttgagatt ggtttcctac acgcttttgt ttgattttat tgtttctcgt
    12901 gttattgatt tgattggtga aggaggatat gccggcaaag gctttatgat tatcacaaaa
    12961 cgtcctgacc aacttgctaa ggcgattaat gatgacctcg gaagaggtgt tacttttatt
    13021 tctggtcaag gctactatag taaagaaaat ttgaaaatca tctactgtat tgtcggaaga
    13081 aatgaaattg tgaaaacgaa ggaaatgatt catcgaatcg atcctcaagc ctttataact
    13141 attacagaag cccatgaaat cctaggagaa ggcttcacct ttgaaaaaga ataaaaagag
    13201 gtaatgtcgt gacctcaaaa gttagactaa atcatctatc ttttgggtta cagacaacct
    13261 cttttttgtt ttatttactc aagctcttaa gaccaattcc gagttacttc ttcatcagcc
    13321 tttaactgat ccactaattg gtcaactgag tcaaatttgg tcatatcacg aatgcgatca
    13381 agccaataaa ccatgacggt ttccccataa atatcttgat taaaatcaaa aatattgact
    13441 tcaaaacgtg cttcttctcc atcaaaggtc acatttttcc cgacactagc catagcacga
    13501 tacttctgtc tttgaatctc aacatcaacg acataaacgc catctgctgg catataagta
    13561 cggtctaaaa gcactaaatt cgctgtcgga taaccaattg tacgaccacg agcattacca
    13621 tgaactacca tacctcttga tggaagcggt gcccccaaaa gttttcctgc ttctttcaca
    13681 tttccatcta aaatagcttg acggatacga gttgaactaa tctttccttt ctcatcttct
    13741 acaggtggaa caatgataac ttctccatca aagtaatcct ttaaatcttc tgctgttttt
    13801 ttgtcagaac caaatgtata atcaaaacct gcaacaataa ttttggcatt catagccttg
    13861 atataagttg caaagaattc ttgtgcagta agactagcga attgactact aaaatcaagg
    13921 agatataatt cttctacacc ttcgcgcttt aattttcttt cacgttcagc agggttcaaa
    13981 atatgcaaaa acaaatctgg atgataaggc tctaaagcga tctttggaga ttcattaaag
    14041 gtcataacga cgataggtaa taaatccttt ctcgcagcct tgttggcaac acgaaataat
    14101 tcttgatgcc ccttatgtat gccatcaaaa tagccgagaa caacgactga atcagatggt
    14161 gtgccaatat ctttttggtt ttttatagga atagtaataa tcataaaata attatatcat
    14221 agcgatagct atttctggaa cagaaaatct gaaatgttgt ttttttcaca tgaagtgtac
    14281 ctgttttcaa aaagcacttt attctatcgt tgcttaacta tgaactttgc aatattcttc
    14341 tcaaaaactt gtaggacatc ttcaaaattt tgcaaggagt gattagactt gttcggtaac
    14401 cataaagtgt catactatgt tatgtatgaa aaagcaatgc aactaactcc tgagaacttt
    14461 aaattactaa ttggtgccga aaaggtagaa tttagaatcg aggtacacct atggctgtaa
    14521 aatttacaaa atgagacaac ttgggcaaga tgtttgaaga atttcctaaa ctcccatcta
    14581 gtgtgcttca gactaggcta tttttctctc catctgttag cttggattct cagaccgttt
    14641 cagctaaaga atatcttttc ccttatcaga aggaacggct caagccattc agacaagtga
    14701 agggacgaca agccaatatt tgaaaccaga tagcagttct tatagtcaat tgaaataaaa
    14761 tctgaagaaa tcgagtagga aactcatatc aatttttaac agtgttctat tccagattca
    14821 tactcaatga aaattaaagt gcaaactagg aagttagccg caggctgtac ttgagtacgg
    14881 caaggtgaaa ttgacgtggt ttgaatttga ttttcgaaga gtatcaatcc actatacata
    14941 ttaaaaagta tgggtatcaa aataaaaaac aggctctccg aaaactcgga aagccttatt
    15001 ttaagctgtt tctagcttcc tcacctttac atttcaaggt tcgggataaa aggttcaatg
    15061 gaccttttta tttagcgatt gggtaaacag aaacttgttt tttatcgcgt cctttacgtt
    15121 caaagcgtac tacgccttca actttagcga acaaagtatc gtctccacca cgaccaacgt
    15181 ttacacctgg atagatgtgt gtaccacgtt gacggtaaag gattgatcca cctgttacag
    15241 tttgtccgtc agctgcttta gctccaagac gttttgcttg tgaatcacgt ccgtttgatg
    15301 tagaacctcc accttttttg tgggcgaaaa gttgcaagtt gttaagagtc atttttaaca
    15361 taatgttttc ctccgtgtta gttttctgtg ataactctgg tttggacgaa ctcagaatag
    15421 ttctccgata agtttgccat acctaagaaa aatgattcaa agaataactg ggtcatttct
    15481 ctctggtgtg aaggaagatc ttttggtatt tcaaccatca gatagccacc ttcatcttcg
    15541 tttaattcta ggattggttc atagcctgca aatttctcaa tagaattgat aaagttaatg
    15601 gcaagcgtag aaaccgatgc acacacgaca tctaagccgt attcgccact ctcggcgtgt
    15661 ccagtaattt ccgcactcct cagctcgcca tcttcggctc tctcaaagac tgcctgtatc
    15721 atgtgttctc cttaaaatta agcgttgatt gcgttgatga caacttttgt atatggttga
    15781 cggtgacctt gtttacggtg gctacctttt ttaggtttgt acttgtaagt aaccactttc
    15841 ttttgttttc cttgtttttc aacagttcca actacagtag ctccagcaac aagtggagtt
    15901 ccgacaacag tgttttcacc accaacaaga acaacttcgt taaaagtaac ttcttgacca
    15961 gcttcaacgt tcaatttttc aacgtaaact gcttgaccaa cttcaacttt aacttgtttt
    16021 ccgccagttt tgataattgc gtatgtgctc attatgcacc tcctatgatt tttatgggtt
    16081 tccccgattt tttgtgaaga ctcgcctagc atcgtgggac gaaccactta aacttgaata
    16141 atcaagcaac gatgttcgtg cggttgcaca ggatcgtgca tagtcaactc ttcaagtata
    16201 gcatatctcc tattttctta caagtaataa cacctaaaat caagcttttt cttttacttt
    16261 tttctgccaa gaggcaaaaa gcatgctgag gtaaaaaacg ctcatcataa taggaacacc
    16321 aagaatggtc ttttcatgat agaaaatcgt caaataggct gaaaagacaa cgccaaggac
    16381 aaaactacta agcaggctaa caaatatgaa tccttcacgc aaaaaaggag tgtgcttggt
    16441 tcggaaataa tctccaaaag ccagcatggt ccgtttgata ttccctgtca taaaagcgtt
    16501 attataggca atacccgaca cttctccaaa agcagttgtc accagtccca tacagaaggc
    16561 caagggcggc actagataga tattatccac agtttgcggc acaaaagcaa taatgattga
    16621 taagattgcc aagggaatca aggacagaat aggttttttc acaattctca atttttcctt
    16681 ataaatcgtt aataaaaaga ctcccatcat aaacgctagc aaggtgagaa ccttgtccct
    16741 aacatccgaa acattatttt taattaattc tactgaaaga aagacaacat ttccagtttg
    16801 tccagctaca agggtattcc cgcgaacaat aaaagtgtaa gcatccacat atccagcaca
    16861 aaacgtcaaa aaaagtgcta accttttaga ctgacgtgat atttttctta taggtaataa
    16921 cctcatttta cctcccattg tattttctct tagaaatatt gtaccatttt ctttctaaaa
    16981 aatcgtaggc taccatttag attttactat tagcataaaa ataataatag acaactattt
    17041 atccaaaaat agatagatgt aacatgtttg caaacaaagc atacgaacct ttagtaaaat
    17101 catttccatg aaactagaat agagccctct tagcaaaaat cattatttta atttatttct
    17161 aatcactcct tgacataaat aactctcacc aataaaagac tatgtcttaa aaaaatggta
    17221 taataaaatc aatacttggg cttgatggct atgctactaa taacaattag gagagaaaat
    17281 caggcacttg ttaacaacaa ggattatccc cttgagatga aaggaacttt agaaatctta
    17341 tgatgaacat gcaaaacatg atgcgtcaag cacaaaaact tcaaaaacaa atggaacaaa
    17401 gccaagctga acttgctgct atgcaatttg ttggcaaatc tgctcaagat cttgtccaag
    17461 cgaccttaac tggcgataag aaagttgtca gcattgattt caatccagct gtcgttgacc
    17521 cagaggacct tgagactctt tctgatatga ccgttcaagc catcaactct gctcttgaac
    17581 aaatcgatga aactaccaag aaaaaactgg gtgctttcgc tgggaaatta cctttctaaa
    17641 aacaaggagc tagaacaatg cttgtcgata acaaaggcta agaaaggtgc aaaaatgact
    17701 ctataatatt tgtagtgggt aaatcc
//
LOCUS       DAYYYC010000047        17598 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.047, whole genome shotgun sequence.
ACCESSION   DAYYYC010000047 DAYYYC010000000
VERSION     DAYYYC010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17598
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.047"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(162..410)
                     /locus_tag="ACHBV5_001635"
     CDS             complement(162..410)
                     /locus_tag="ACHBV5_001635"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9967400.1"
                     /translation="MASTSLQAPAKICFILIKLYSPYAFLSKYLGAILLSFFCYYAKE
                     IGCNNLTLSVWNDNEGALRFYQRQGMKPQETTMEMIID"
     gene            complement(358..1440)
                     /locus_tag="ACHBV5_001636"
     CDS             complement(358..1440)
                     /locus_tag="ACHBV5_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFM9967401.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTIFETAEFENLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     IIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1566..2348)
                     /gene="gatD"
                     /locus_tag="ACHBV5_001637"
     CDS             complement(1566..2348)
                     /gene="gatD"
                     /locus_tag="ACHBV5_001637"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HFM9967402.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2348..3691)
                     /gene="murT"
                     /locus_tag="ACHBV5_001638"
     CDS             complement(2348..3691)
                     /gene="murT"
                     /locus_tag="ACHBV5_001638"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HFM9967403.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3803..5119)
                     /locus_tag="ACHBV5_001639"
     CDS             complement(3803..5119)
                     /locus_tag="ACHBV5_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HFM9967404.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5313..6539
                     /locus_tag="ACHBV5_001640"
     CDS             5313..6539
                     /locus_tag="ACHBV5_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HFM9967405.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGILGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            6738..8312
                     /locus_tag="ACHBV5_001641"
     CDS             6738..8312
                     /locus_tag="ACHBV5_001641"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFM9967406.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8576..9364
                     /gene="codY"
                     /locus_tag="ACHBV5_001642"
     CDS             8576..9364
                     /gene="codY"
                     /locus_tag="ACHBV5_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFM9967407.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9364..9939
                     /locus_tag="ACHBV5_001643"
     CDS             9364..9939
                     /locus_tag="ACHBV5_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFM9967408.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFSPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10021..10106
                     /locus_tag="ACHBV5_001644"
     tRNA            10021..10106
                     /locus_tag="ACHBV5_001644"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10055..10057,aa:Leu,seq:aag)
     gene            10389..11519
                     /locus_tag="ACHBV5_001645"
     CDS             10389..11519
                     /locus_tag="ACHBV5_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9967409.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(11666..11812)
                     /locus_tag="ACHBV5_001646"
     CDS             complement(11666..11812)
                     /locus_tag="ACHBV5_001646"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967410.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            12020..12778
                     /locus_tag="ACHBV5_001647"
     CDS             12020..12778
                     /locus_tag="ACHBV5_001647"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM9967411.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            12865..13377
                     /locus_tag="ACHBV5_001648"
     CDS             12865..13377
                     /locus_tag="ACHBV5_001648"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFM9967412.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13559..14503
                     /gene="metA"
                     /locus_tag="ACHBV5_001649"
     CDS             13559..14503
                     /gene="metA"
                     /locus_tag="ACHBV5_001649"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HFM9967413.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14512..15189
                     /locus_tag="ACHBV5_001650"
     CDS             14512..15189
                     /locus_tag="ACHBV5_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFM9967414.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLIKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15287..16045
                     /gene="tpiA"
                     /locus_tag="ACHBV5_001651"
     CDS             15287..16045
                     /gene="tpiA"
                     /locus_tag="ACHBV5_001651"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFM9967415.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16083..17588
                     /gene="lytC"
                     /locus_tag="ACHBV5_001652"
     CDS             16083..17588
                     /gene="lytC"
                     /locus_tag="ACHBV5_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HFM9967416.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMIQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
BASE COUNT         5282 a         3172 c         3922 g         5222 t
ORIGIN      
        1 ccctgtgcaa tacagaacta aatccttcgg ataaattaat tgtctaactt tttggggggc
       61 agttcattct acacccacta ttatgcgttt tattgtggga agattttcct cattttctag
      121 tgaaattgaa ctttttctaa catcttttga tagatgactt cttaatcaat tatcatttcc
      181 attgttgttt cttggggttt catcccttgt ctttgataaa agcggagagc accctcgtta
      241 tcattccaga cacttagggt tagattattg cagccaattt ctttagcata atagcagaaa
      301 aatgacaata aaatagcccc tagatatttt gaaaggaaag cataggggct atatagttta
      361 atcaaaataa agcaaatctt tgctggtgct tgtaaagagg tcgaagccat ccttggtaac
      421 aacaccgcag tcttcaatac gaacaccgac tttaccaggg atatagatac ctggttcaac
      481 agagaagcac atgccttctt cgatgaccat gtcgtttcct tccatgatag atgggaattc
      541 atggacatcc ataccgatac catgcccgag acggtggttg aagtactcac cataaccagc
      601 tttttcgatg atctcacggg cagcgcggtc cacttcatga gcagtcacac ctggcttgat
      661 aaagtcaaga gcagcttgtt gggcttcaag agtcaagttg taaatatctt tcttgaattg
      721 gtctggtttg ccgacagcga ctgtacgagt catatctgac gcatagccat tgaccagaac
      781 ccccaggtca aagaggagaa gagcatcatt ttcaacctta ttagctgctg gaatgccgtg
      841 tggattcgca gcattatcac cagtcaagac catggtatca aagctcattt cgtaaccttc
      901 acgtttcatg gcaaagtcaa tttgtgcgat gatatctgtc tcagtcttat caagagaaat
      961 attgtcaaaa ccaacatgaa cagccttgtc agcataaaga cctgcaacca tcattttttg
     1021 tacttcatca gctgatttga tgaggcgcat gcgttggata cgaggagtga ggttttcaaa
     1081 ctcagcagtt tcaaaaattg ttttcaaacc atggtatttg gtcaagatga gattgtcaaa
     1141 ctcaacagcg acacgtttga agtcaagttg tggaagagca tgtttgattt tttgccatgg
     1201 attttcagaa tcgacatagc ccactactgg gaaggaaacg gtgctacttg cacgttctac
     1261 ttcaagagct gggacaaaga ggagaggttc ctgatccgct aggacaaaga ggaacatttg
     1321 gcgttcatgg ggatcactgt aaaaaccagt gaggtaattg attgtgacgg ggtcagatac
     1381 gacagcgacg tctagttttt ctgattcaag atatgttagg atttgttgta atttagacat
     1441 atgctacctt ctttctaccc ctctattttg gcaaaaaatg agagaaaatg caagggagaa
     1501 gggtaaaaga aaagacaaaa aactccgaca agataacgga gttctttgat atcattttcc
     1561 tttgtttaag aaaagtcagc cttgcttttg acgtcactgt actcttcagc gatttcttgg
     1621 ctgaggatat cctcataggc agggagttgg atatcctgac catatttctt cttgagggca
     1681 gtagtaacta ggcgataagc cagattggca ttacgagaga ggataggccc gtggaagtag
     1741 gaaccaaaga cattcttata atgaacccct tcaccgacct tttcttcgtt gtttccattt
     1801 ccatagacaa cctgtcccag cggtttttgg tcatcagaga ggaaggtacg accttggtga
     1861 ttttcaaatc catagtaggt ttcatcgaaa tcttcattgt gaatcttgat gtcaccgata
     1921 aaacggttat tggtctggtt gagcgtgtag tgtcccatga cccctagccc ttcgatacgt
     1981 tttcctgaag cttcaacata atattgaccc aatagttgga aaccaccgca gatagccaga
     2041 actacaccgt cgttttggat gtagttgtca atgctctctt ttttagcagg taggtcgtct
     2101 gcaatgatac tttgttcaaa gtcttgacca ccaccgaaaa aggcgatgtc gtagtgattt
     2161 tcatcaaagt catcatggag agaaacgatg tcaacggtca catgggctcc cagtttttca
     2221 gccacatact tgagcatgag gatgtttcca ttgtccccgt aggtattcat gagatttccg
     2281 tagaggtggg caatgttgag ctgatagggg taattgccat cttttgagga aagtgaagta
     2341 taaaccatta gttcatctcc tttctaacaa tctgacgact agccagcagt tcacgaaatt
     2401 ccagcatggc agtataagtt gccagaatat aggcatgctt gcagtcttga ttctcaatgg
     2461 tcttgagaac ttgctccaga ttactcgttt cagtgatttt ctcagctgga tagccagtca
     2521 ctcggaggcg acgagcgatt tcagaatgac gaacaccgcc agcgttgatt tcaggaatgt
     2581 ccatgtcagt gatttgttca aagtctgcat cccagatcca gctagtgtca attccatctg
     2641 catagttggc attaaggagg acagataggc taaatggata aggtgctagt ttgatcattt
     2701 cgatagcttg ggttgcaccg actggatttt taatcaagac aagggtacat tccttgtcac
     2761 cgatatgaaa ggtttcttgg cgtccaaaga cagcacggct cttgtcaaat ccctgtttga
     2821 tgagttgcga atcggcacct aggaaacggg cgatggccac agcagctagg gcgttataga
     2881 tattatagag cccgccgatt tggataccgt attcttggcc gtctatgaca aagcgagagc
     2941 gattgttggt caactcaacc agttttgtca aacgatagtc gagatcagga cgtttacatc
     3001 cacaaccttc acagatatag gcacccaagt ttgcataggt attatgctca tatttgagga
     3061 tgccttggca gtcaggacag agaatccctt cggtattgta gtgagccagt tgggctggtc
     3121 ccttttccaa gtcaaaacca aaatactcta tagggtttgg aatagttggc ttgtagaaaa
     3181 gtggactgtc tccgttaagg agaacagtag cagttggaac tttccgaatg gcatccaata
     3241 tcatgttata ggtagtatag atttcaccga aacggtccat ctggtcacgg aagatattag
     3301 taatgacaaa aagactaggc tggatatagt cacagatacg agatagactg gcttcgtcaa
     3361 tttcgaggac ggcaatattt ttcccagttt tagaagattt ggctgttagg aaggttgttg
     3421 caatccctgt aatcatgttg gcaccgcttg ggttggttag aacttgacca taaacctctt
     3481 ttaaaatgcc gacagtgagg gcagttgtca gggtttttcc atttgttcca gtgacaacga
     3541 caatctcgta gttcttagct aggttttgta aaatatcttt atcaaattga agggcgactt
     3601 tccctgggag cgtacttcca cgtccaagac ggcttaaaac gaagtgggaa gaacgcccag
     3661 caagaaggcc caaagtagtt tttaagttca tgtttctatt atatcacaaa agtatatcac
     3721 aaaagaggga aaagacagat ttggtgtttc gtagaagtaa aaacagccca aagagggctg
     3781 tcagttaaga tgagatttca acttaaatcg caaacaagtc attcaagttc tcagccaagg
     3841 ttgggtgagt gaagatttgt tttgtgaagt aagtgtaagg aatcttgttg tccatagcaa
     3901 cagtaataat gttgatgatt tcttgagaac cttctgagaa gatgcttgca ccaagaattt
     3961 cttttgtttc agtattaaca acagctttga aagctccgcg aaggtctcca tttacgtgac
     4021 cacgaggcat ggctgcaaca gggatttctt tcactgcgta tggaagtttc aaatcagctg
     4081 cttggctttc agtcaaacca acttgtgaaa gtgcaggtgt gatgaacata gtatttggca
     4141 cattgagacg gtcctcaagt gtgtagctgc catctccagc aaggtagctg taaacaacac
     4201 ggaagtcatc aagtgaaatg taagtaaatt gaagaccacc gttgacatct ccaactgcaa
     4261 agacaccagg aacgtttgtt tgacagtgtt tatctacttt aatagcgcca cgttcagtta
     4321 gttcaatatc tgtattttca agttgaagtg gttctacatt tggtttgcgt ccagttgcgt
     4381 agagaagggc gtcgaaacgg taagtttcgt cttcagttac gacaagcact tggtcaccgt
     4441 cgtttttaat ttcagtagta tggatatttt gaagcaattc aataccgtct tcttccatgt
     4501 attgtttagc aagagctgcg atggaaggtt ctgcacgagg taggaatgta tccaaggcat
     4561 ctaggactgt aaccttgctt cctagtttat tgtaaaggcc agcaaattca agaccgatat
     4621 ttccgccacc aaggactcca agtttttcag gcaatttatc caagctttgg atacctgttg
     4681 agtcaaagac gtttttgctt gtagcaagtc cagggattgg caagacgttt gaaacagcac
     4741 cagtgttgat gacgatagtt tcagcagtca attcttgttt ttcatcacca gcttggattt
     4801 cgatgacttt atttgaaagg aagtgagctt cagcatcaaa gatatcgacg ccagtaccag
     4861 caacagtcgt atagttttta ccgttgaggc gaccagtgat cgtgtttttg gtagcaatga
     4921 cttcttcaaa agacaagtct ttctcagcag caaccagcaa agttttagtt gggatacaac
     4981 cgatgttgat acaagttcca ccgtacatag ctttgctacg ttcaacgagg gcaacttttt
     5041 tgccagctga agccaattta ccagctagtg ttttaccagc tttaccaaat ccgataacga
     5101 ttaaatcata agttaacatt tagaattcct cctattcgaa ttacattcta gcacaagaaa
     5161 aaaacttttg cacaattctg ctacgaaaaa gacagaaaaa tatgaaaacg cttttcaggc
     5221 aaaaaactag taattttttg acaagcttga taaactaaaa tcctatctat ttttatataa
     5281 gatagaataa atgttcgaaa ataggaggtt ttatgaaatc gaatcgttat attattgcct
     5341 ttgctggggt cattttacac ttaatgctgg gttcgactta tgcctggagt gtttatcgta
     5401 accctattat tgaaaaaacg ggatgggatc aggcttctgt tgccttcgcc tttagtctag
     5461 caatcttttg tttgggctta tcggctgcat ttatggggcg tttggtagaa aaatttggtc
     5521 cgagagtcat ggggagtcta tctgcttttc tatacgcagg tggaaatatc ttaacaggat
     5581 ttgcaataga ccgtcaggaa ctgtggttgt tgtatctagc ttatggcatt ttaggtgggc
     5641 ttggtttggg agcaggctat attacccctg tgtcaacgat tataaaatgg tttcctgata
     5701 aacgtggtct cgcaacaggt ttagcgatta tggggtttgg ttttgcttct ttattgacta
     5761 gtcccatagc gcaacatctc atcgcagggg tagggcttgt agaaactttt tatattttag
     5821 gtgcaagtta ctttattatc atgctcctag cttcacaatt cattaagcgt ccaaatgagc
     5881 aagagcttgc aattttatct gcttcaggga aagaaaaaac agactctctg acgcaaggga
     5941 tgactgcaaa tcaggctcta aaaagcaatc ggttttatat gctttggatt attttcttta
     6001 tcaacatagc ttgtggttta ggcttaattt cagcggcatc gccaatggca caggagatgg
     6061 ctggcttgtc tacaagtcat gcagcagtaa tggtgggtat tttggggatt ttcaatggat
     6121 ttggtcgctt gctctgggcg agtttgtctg actatatcgg tcgccctcta acctttagta
     6181 tattactgct tgtcaatctt ttcttttctc tctcactttg gctctttaca gattccgttt
     6241 tatttgtagt tgctatgtct attttgatga cttgctatgg agctggtttt tctttgattc
     6301 cagcttatct cagtgatatt tttggaacca aggaattggc cgctctgcat ggttatattt
     6361 taacagcttg ggcaatggct ggtttagcgg gacctatttt attagcagag acttataaaa
     6421 tggctcattc gtacacacaa accttgttcg tttttctcat tttatacagt atcgccttgg
     6481 ctttgtctta ttatctaggt cgttcaatca aaaaagaaag tcaaaaaccg cttacatgat
     6541 tttctgtaga aatggggcta tcttttgctc tggtcttgtg ttatactaga taggttgcaa
     6601 agaaaacagt acttttcttt tgtggaaaag aagcaacacg attttatatc tagttatatg
     6661 aaaatacgtc ataaaaagaa aagtataaac taagccctat agggtggctt cgcaccacct
     6721 ttagaaagaa gaataacgtg aaatttaatg aattaaactt gtctgctgat ttgctagcag
     6781 aaattgaaaa agctggtttt gtagaagcta gtcctatcca agaacaaact attcctttgg
     6841 cccttgaagg caaggatgtt atcggtcaag ctcagactgg tacaggaaaa actgcagcct
     6901 ttggcttgcc tacccttgaa aaaatccgta cagaagaagc gactatccaa gctttggtca
     6961 tcgctccaac tcgtgaacta gctgtccaaa gtcaagaaga actcttccgc tttggtcgta
     7021 gtaagggagt caaagtccgt tcagtatatg gcggatcaag cattgaaaaa caaattaagg
     7081 ctcttaaatc tggtgcccat atcgtggtgg gaactccagg tcgcctcttg gacttgatta
     7141 aacgcaaggc cttgaaatta caagacattg aaacccttat ccttgacgaa gcggatgaaa
     7201 tgcttaacat gggcttcctt gaagacatcg aagccattat ttcccgtgta cctgagaacc
     7261 gtcaaacttt gcttttctca gcaactatgc cagatgccat caaacgtatc ggtgttcagt
     7321 ttatgaaagc ccctgaacat gtcaagattg cggctaagga attgacaaca gaattggttg
     7381 accagtacta tatccgtgtt aaggaacaag aaaaatttga caccatgact cgtctcatgg
     7441 atgtggcaca accagaactc gctattgtat ttggtcgtac caaacgccgt gtggatgaat
     7501 tgactcgtgg tttgaaaatt cgtggcttcc gtgcagaagg aattcatggc gacctagacc
     7561 aaaacaaacg tcttcgtgtc cttcgtgact ttaaaaatgg caatcttgat gttttggttg
     7621 cgacagacgt tgcagcgcgt ggtttggata tttcaggtgt gacccatgtc tacaactacg
     7681 atattccaca agatcctgag agttatgttc accgtatcgg tcgtacaggt cgtgctggta
     7741 agtcaggtca atctattact tttgttgctc caaacgaaat gggttacctt caaatcattg
     7801 aaaacttgac taagaaacgc atgaaaggtc tcaaacctgc aagtgtagaa gaatccttcc
     7861 aatcaaaaaa acaggtagct ctcaagaaaa tcgaacgtga ttttgcagat gaaaccattc
     7921 gtgccaactt tgagaaattt ggtaaggatg ctcgcaaatt ggctgctgag tttactccag
     7981 aagaattggc aatgtatatc ttgagtctga cagtccaaga cccagatagc cttccagaag
     8041 tggagattgc acgtgaaaaa ccactaccgt ttaaaccatc aggtaatggt ttcggtggta
     8101 aagctaaggg aggtcgtgga ggccgtcgtg gggacgaccg tcgagagcgt gatcgccgtg
     8161 gcaatggtcg ccgtgatgag ttcaaaaaag gaagtcgtgg caacgatcgt tttgataagg
     8221 aaaaacgtta ccgtaaggat aataaaaaac cacgcaatac tttaagcgaa aagcaaacag
     8281 gctttgttat tcgtaacaag ggcgataaat aagaaaaagc ggttcaaaat gaatcgcttt
     8341 tttatataag gagaccgaat gtgaaaagac aaataaaatt attatattat cttttataat
     8401 gttatgatac acaaaaatag gcaacttgtc aatagaaaag gaacaattta attaaaaata
     8461 ttctggtttt taattaaatt gtaagtcaat gcaagtcaat aaggaatttt cagataatta
     8521 ttgaaaaaga gacgttttta tgttataatg atagcgatta aattcgaggt gaaaaatggc
     8581 acatttatta gaaaaaacta gaaaaattac atcaattttg aaacgctcag aggagcagtt
     8641 gcaggatgag cttccttaca acgctattac gcgtcagtta gcggatatta ttcattgcaa
     8701 tgcctgcatt atcaatagta agggacgtct gcttggctat tttatgcgtt ataaaacaaa
     8761 tacagatcgc gtagagcaat tcttccaaac taagattttc ccagatgact acgttcaagg
     8821 ggctaatatg atttacgaaa cagaagcaaa cttgcctgtt gagcatgata tgagtatttt
     8881 ccctgttgag agtagagatg attttccaga tggcttgacg actattgcac cgattcatgt
     8941 atcggggatt cgccttggtt ctttgattat ttggcgtaat gataaaaaat tcgaagatga
     9001 ggacttggtt cttgttgaga ttgccagtac cgttgttggg attcagcttc ttaacttcca
     9061 acgtgaagaa gatgagaaaa atattcgtcg tcgtactgct gtcaccatgg cggtcaatac
     9121 cctttcttac tccgaactcc gtgctgtttc agcaatttta ggggaattaa atggaaatga
     9181 agggaagttg actgcgtcag tgattgcaga tcgtatcgga atcactcgct ctgtgattgt
     9241 caatgctctt cgtaaacttg agtctgcggg gattattgaa agtcgctcac ttggaatgaa
     9301 gggaacctat cttaaggtct tgatttcaga tatttttgaa gaagtgaaga aaagagatta
     9361 ctaatgacaa aggctttaat ttcgattgat tatacagaag attttgttgc tgatagtggg
     9421 aaactaacag caggtgctcc agctcaggcg atttcggatg ccatcagcaa ggtaactcga
     9481 ttagcttttg aacgaggaga ttatatcttc tttactattg atgctcatga agaaaacgat
     9541 tgtttccatc cggaaagtaa gttattttct cctcataatc tgattgggac gagtggacgg
     9601 aatttatatg gagatttggg gatcttttat caagagcatg gttcagacag tcgtgtcttt
     9661 tggatggata aacgccatta ctcagctttt tcagggactg acctagatat tcgtttgaga
     9721 gagcgtagag tgtctaccgt tatcttaaca ggtgtcttga cggatatctg tgtcctacat
     9781 acagctatag atgcctataa tctaggatat gacatcgaga ttgttaaacc agctgttgct
     9841 tccatctggc ctgaaaatca tcaatttgcc ctaggtcatt tcaaaaatac actcggagct
     9901 aagttagtag atgaaaatct aaatgaactt tctgagtaac ctggttggtg aaaatgaaaa
     9961 aatttgaaaa aaagtgttga caagcatccc aaaagttgat atactagtaa agtaatcgat
    10021 gcggggatgg cggaattggc agacgcgcag gactaaggat cctgtgaccg ctttaggtcg
    10081 tgagggttca agtccctctc tccgcatagg aaaagagtta gctaaagcta gctcttttgt
    10141 atttctctaa aaaattagaa tccagtcaaa tgtagtggag aatcagcgaa aatatgggaa
    10201 aactgatcct tgtttctgct tttgtcatag aagaataata aagattatct tcttcaaatt
    10261 ctccgatatt ctctaaagtt ttgtgcaagt tgcacagaac ttttttattt ttttggtcat
    10321 cttgccatag aaatataaag cgttttcatc tataatataa ttatcaaaag acaaaaggag
    10381 ttcacctcat ggtagaattg aatcttaaaa atatttacaa aaaatatcca aacagcgaac
    10441 actattcagt tgaagatttc aacttgaaca tcaaagataa agaatttatc gttttcgtag
    10501 gaccttcagg atgtggtaaa tcaactacac tccgtatgat tgctggtctt gaagacatta
    10561 cagaaggtac tgcatctatc gatggcgtgg ttgtcaacga cgtagctcca aaagaccgtg
    10621 atatcgccat ggtattccaa aactacgctc tttacccaca catgactgtt tatgacaaca
    10681 tggctttcgg tttgaaattg cgtaaataca gcaaagaaga cattaacaaa cgtgttcaag
    10741 aagcagctga aatacttgga ttgaaagaat tcttggaacg taaaccagct gacctttcag
    10801 gtggtcaacg tcaacgtgtt gccatggggc gtgcgattgt ccgtgatgcg aaagtattct
    10861 tgatggacga acctttgtca aacttggatg ccaaacttcg tgtatcaatg cgtgctgaaa
    10921 tcgctaaaat tcaccgtcgt atcggagcta caactatcta tgtaactcac gaccaaacag
    10981 aagcgatgac acttgcagac cgtatcgtta ttatgtcagc tactaagaac cctgctggta
    11041 caggtactat cggacgtgta gaacaaatcg gtactcctca agaagtttac aaaaatccag
    11101 ttaacaaatt cgttgcagga ttcatcggaa gcccagctat gaacttcatc accgtgaaat
    11161 tggttggtag cgaaattgtt tctgacggtt tccgtttgaa agtgccagaa ggagcattga
    11221 aagttcttcg tgaaaaaggc tacgaaggaa aagaattgat ctttggtatc cgtccagaag
    11281 acgtgaatgc agaacctgct ttccttgaaa cattcccaga ctgtgttgta aaagcgacta
    11341 tctctgtatc agaactgctt ggttcagaat ctcaccttta ctgccaagtt ggtaaagacg
    11401 agtttgttgc aaaagttgat gctcgtgact acttgcaaac aggtgcaaca gttgagcttg
    11461 gatttgactt gaacaaagca cacttcttcg atgtagaaac tgaaaaaaca atctactaaa
    11521 ataaataaaa ttcaaagcac tacaagaaaa gatatctctt tatcaattgt agtggagaga
    11581 tatcagttaa tctagggaga gaaacaaaat gcttctctcc tttttgctag ggaagtcata
    11641 ttatgcatct atattgtgat gctctttaat actcttcgaa aatctcttca aaccacgtca
    11701 acgtcgcctt gccgtacgta tgattactga tttcgtcagt tttatctgca acctcaaaga
    11761 tgtactttga gcagcttacg gctagtttcc tagtttgctc tttgatttcc attgagtatt
    11821 atttgtgggt accatctaca agtgaagcta tatgcgtaaa ctacgtgagc aattgaattc
    11881 gaactagaga ggtaataata aatttatgct atagttatgg tgacttgtat gcttttgatt
    11941 ctagtttatc aaataataga ttagaattgt cagataatat cattttgtgt tataatgaag
    12001 aaaaaacaga ggtgttcaaa tgtcagaagc aggtcataag tttttagcaa aattggggaa
    12061 aaaacgctta cgtccaggtg gaaagcgtgc cacagattgg ttaattgcag aaggaggatt
    12121 ttcaaaagaa aagagaatac tagaggttgc gtgtaatagg ggaactacag caattgagtt
    12181 ggcacagcgt tttggttgca agataactgc tgttgatatg gatgctcaag ctttagaagt
    12241 ggctaaaaaa tctgctggaa cggcaggtgt tgctcattta atcagttttg aaagagcaaa
    12301 tgcaatgaaa cttccttatc aagatgctag ttttgatatt gttataaatg aagctatgct
    12361 gactatgcaa gccgatcaag ctaagaaaaa atgtgtaatg gaatatctaa gggtattaaa
    12421 acctggaggt cttctcttga cacatgatgt gcttcttaag gaagctaaag agtctatcag
    12481 acaggaatta tcacaagcaa ttcatgtaaa tgtaggtcct ttaactcaag atggttggga
    12541 acaggtgatg atagaatcag gttattgtga tgtgaaagca ttgactggtg aaatgacatt
    12601 aatgaaatta tcgggtatga tttatgacga aggtttgcta ggaactttga aaatttgtgt
    12661 aaatgcttgt aaaaaggaga atagaaagca gtttttaact atgtataaaa tgtttgctaa
    12721 gaataaacag aaattgggct ttattgcgat ggctagttat aaatcgtcaa aacgttagat
    12781 aattattgaa gttaactttt ccttttttct ttcttaaaaa atatgctata atagagagta
    12841 aaaaactttg aaagaaagaa aaagatgaat ttaaaagatt acattgcaac aattgaaaat
    12901 tatccaaagg aaggcattac cttccgtgat attagtcctt tgatggctga tggaaatgct
    12961 tatagctacg ctgttcgtga aatcgttcag tatgctactg acaagaaagt cgacatgatc
    13021 gtgggacctg aagctcgtgg atttatcgtg ggttgtccag ttgcctttga gttgggaatt
    13081 ggttttgcgc ctgttcgtaa gccaggtaaa ttgccacgcg aagttatttc tgctgactat
    13141 gaaaaagagt acggtgtcga taccttgact atgcacgcgg atgccattaa gccaggtcaa
    13201 cgtgttctta ttgtagatga ccttttggcg acaggtggaa ctgttaaggc aactatcgag
    13261 atgattgaaa aacttggtgg tgttatggca ggttgtgcct tccttgttga attggatgaa
    13321 ttgaacggcc gtgaaaaaat tggtgactac gactacaaag ttcttatgca ttattaatga
    13381 aaacagtccc tagggctgtt ttctctacac taggatataa aaatagacta taactagtta
    13441 gagaaaaact ataattgaaa actatatctt cttgcagtat aataaaagga ctaagtgttt
    13501 gagatttgtc ttcaaacata tgcaattatt cctgaaagag tacagttagg agagggttat
    13561 gccgattcga attgataaaa aattgccagc tgttgagatt ttacggacag agaatatctt
    13621 tgtcatggat gatcaacgtg ctgcccacca agatatccgt cctttgaaga ttttaatttt
    13681 aaatctcatg ccacagaaaa tggtcacaga gacccagttg ttgcgccact tggctaatac
    13741 acccctacaa ctggatattg attttctcta tatggagagc caccgttcta aaacaactcg
    13801 ttcagagcac atggagacct tctataaaac ttttcctgaa gtcaaggatg agtattttga
    13861 tgggatgatc atcacgggtg ctccagttga gcatttacca tttgaggaag tggactattg
    13921 ggaggaattt agacagatgc ttgagtggtc taagactcat gtctattcga cccttcatat
    13981 ctgttggggg gctcaggctg ggctttatct gcgctatggt gtagaaaaat accagatgga
    14041 cagtaagcta tcaggtattt atcctcagga caccctaaaa gagggtcacc ttctatttag
    14101 aggctttgat gatagctatg tatcccctca ttcacggcac acggagattt ctaaggaaga
    14161 ggtcttaaac aagaccaatc tcgagatttt atcagaagga cctcaggttg gggtttctat
    14221 tttggccagt cgtgatttac gagaaattta tagttttggt catttggagt atgaccgtga
    14281 taccttggca aaagagtatt ttcgagatcg tgatgcaggt ttcgacccac atattccaga
    14341 aaattacttt aaagatgatg atgttaatca ggtaccttgt ctttgttggt cttcatctgc
    14401 agccctcttt ttcagtaatt gggtaaacca tgcggtctat caggagacgc cttttgattg
    14461 gagaaagata gaagatgatg catctgcata tgggtattta taagaggaat tatgacatat
    14521 ttagacgctt ttaaatcagg taccttggtt ttaccgagtg ccctgctctt gcattttaag
    14581 gaactctttc cttctagcga cgattttctg gtttggcaat ttttctattt gcaaaatacg
    14641 acaggcttag aagaaatgtc gccaagccag attgctgaaa ggattggcaa ggaaatttcg
    14701 gatgtcaacc agtccatttc taatctgacg gaaaggggac tgctccagta tcgtactatc
    14761 gaattaaatg gcgaaattga attgctcttt gatgctagtt tggccttgga acgtttggat
    14821 gacctgtttg gagcagttcg ttcaagttca gaccagctaa cacctcaaaa ccagctcaag
    14881 gatttggtgg aaaccttcca gcaggagttg ggacgattgt tgacgccttt tgagattgag
    14941 gatttgatca agacactaaa ggaagatgga accagtgctg acttgattaa ggaggctctt
    15001 cgtgaagctg ttttgaatgg aaaaccaaac tggaagtaca ttcaggcgat tttgagaaac
    15061 tggcgccatg aaggaatcaa gagtgtggct caaattgagg ccaagagagc agaaagagaa
    15121 gcaagcaatc ctcagttgac acaggtatct gcagatttca gaaatgccat ggatctctgg
    15181 aaggattaat ccatgcaagt aggcttgaaa tccgagtaag atttgcaagc tgtgtataat
    15241 tgtgatagaa taaatagaaa ataaattgaa aaaagaggta tgtgaaatgt cacgtaaacc
    15301 atttatcgct ggtaactgga aaatgaacaa aaatccagaa gaagctaaag cattcgttga
    15361 agcagttgca tcaaaacttc cttcatcaga tcttgttgaa gcaggtatcg ctgctccagc
    15421 tcttgatttg acaactgttc ttgctgttgc aaaaggctca aaccttaaag ttgctgctca
    15481 aaactgctac tttgaaaatg caggtgcttt cactggtgaa actagcccac aagttttgaa
    15541 agaaatcggt actgactacg ttgttatcgg tcactcagaa cgccgtgact acttccatga
    15601 aactgatgaa gatatcaaca aaaaagcaaa agcaatcttt gcgaacggta tgcttccaat
    15661 catctgttgt ggtgaatcac ttgaaactta cgaagctggt aaagctgctg aattcgtagg
    15721 tgctcaagta tctgctgcat tggctggatt gactgctgaa caagttgctg cctcagttat
    15781 cgcttatgag ccaatctggg ctatcggtac tggtaaatca gcttcacaag atgatgcaca
    15841 aaaaatgtgt aaagttgttc gtgacgttgt agctgctgac tttggtcaag aagtcgcaga
    15901 caaagttcgt gttcaatacg gtggttctgt taaacctgaa aatgttgctt catacatggc
    15961 ttgcccagac gttgacggtg cccttgtagg tggtgcgtca cttgaagctg aaagcttctt
    16021 ggctttgctt gactttgtaa aataatcagt aagtagcaaa agctaggtgg aacagcattc
    16081 agatgtctgt tacatttttt ataggagagg aaagattgaa aataaaaatt ggattagcaa
    16141 gtatctgttt actaggcttg gcaactagtc atgtcgctgc aaatgaaact gaagtagcaa
    16201 aaacttcgca ggatacaacg acagcttcaa gtagttcaga gcaaaatcag tcttctaata
    16261 aaacgcaaac gagcgcagaa gtacagacta atgctgctgc ccactgggat ggggattatt
    16321 atgtaaagga tgatggttct aaagctcaaa gtgaatggat ttttgacaac tactataagg
    16381 cttggtttta tattaattca gatggtcgtt actcgcagaa tgaatggcat ggaaattact
    16441 acctgaaatc aggtggatat atggcccaaa acgagtggat ctatgacagt aattacaaga
    16501 gttggtttta tctcaagtca gatggggctt atgctcatca agaatggcaa ttgattggaa
    16561 ataagtggta ctacttcaag aagtggggtt acatggctaa aagccaatgg caaggaagtt
    16621 atttcttgaa tggtcaagga gctatgatac aaaatgaatg gctctatgat ccagcctatt
    16681 ctgcttattt ttatctaaaa tccgatggaa cttatgctaa ccaagagtgg caaaaagtgg
    16741 gcggcaaatg gtactatttc aagaagtggg gctatatggc tcggaatgag tggcaaggca
    16801 actactattt gactggaagt ggtgccatgg cgactgacga agtgattatg gatggtgctc
    16861 gctatatctt tgcggcctct ggtgagctca aagaaaagaa agatttgaat gtcggctggg
    16921 ttcacagaga tggtaaacgc tatttcttta ataatagaga agaacaagtg ggaaccgaac
    16981 atgctaagaa aatcattgat attagtgagc acaatggtcg tatcaatgat tggaaaaagg
    17041 ttattgatga gaacgaggtg gatggtgtca ttgttcgtct aggttatagc ggtaaagaag
    17101 acaaggaatt ggcgcataac attaaggagt taaaccgtct gggaattcct tatggtgtct
    17161 atctctatac ctatgctgaa aatgagaccg atgctgagaa tgacgctaaa cagaccattg
    17221 aacttataaa gaaatacaat atgaacctgt cttaccctat ctattatgat gttgagaact
    17281 gggaatatgt aaataagagc aagagagctc caagtgatac agacacttgg gttaaaatca
    17341 tcaacaagta catggacacg atgaagcagg cgggttatca aaatgtatat gtctatagct
    17401 atcgtagttt attacagacg cgtttaaaac acccagatat tttaaaacat gtaaactggg
    17461 tagcggccta tacgaatgct ttagaatggg aaaaccctta ttattcagga gaaaaaggtt
    17521 ggcaatatac ctcttctgaa tacatgaaag gaatccaagg gcgcgtagat gtcagcgttt
    17581 ggtattaagc gatgattt
//
LOCUS       DAYYYC010000048        16156 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.048, whole genome shotgun sequence.
ACCESSION   DAYYYC010000048 DAYYYC010000000
VERSION     DAYYYC010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16156
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.048"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            194..1639
                     /gene="cps4A"
                     /locus_tag="ACHBV5_001653"
     CDS             194..1639
                     /gene="cps4A"
                     /locus_tag="ACHBV5_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HFM9967417.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVITALVLLVALLGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAVYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1641..2372
                     /gene="cps4B"
                     /locus_tag="ACHBV5_001654"
     CDS             1641..2372
                     /gene="cps4B"
                     /locus_tag="ACHBV5_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HFM9967418.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKVKELFVDNPRKIIMDQLI"
     gene            2381..3073
                     /gene="cpsC"
                     /locus_tag="ACHBV5_001655"
     CDS             2381..3073
                     /gene="cpsC"
                     /locus_tag="ACHBV5_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HFM9967419.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSMTRIYVVNRNQGEKSGLTNQDLQAGSSLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKDLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPATSPSSPNIKRSTLIGFLAGVIGTSVIVLILELLDTRVKRPKDIEDTLHMT
                     LLGIVPNLNKLK"
     gene            3083..3772
                     /gene="cpsD"
                     /locus_tag="ACHBV5_001656"
     CDS             3083..3772
                     /gene="cpsD"
                     /locus_tag="ACHBV5_001656"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HFM9967420.1"
                     /translation="MPTLEIAQKKLEFVKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PEEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGTVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEVNKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GFYGNYGKKII"
     gene            3783..5150
                     /locus_tag="ACHBV5_001657"
     CDS             3783..5150
                     /locus_tag="ACHBV5_001657"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFM9967421.1"
                     /translation="MDEKGLKIFLAVLQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYVQYTSE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            5154..5897
                     /locus_tag="ACHBV5_001658"
     CDS             5154..5897
                     /locus_tag="ACHBV5_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HFM9967422.1"
                     /translation="MRDRIQLLGVTIDLLTMNETIDIVEQYVLEKRPLHLMGVNADKI
                     NQCHTDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMQCLLELSNKKG
                     YSVYFFGAKEEVLQDMLKVFKRDYPNLIVIGHRNGYFSEEDEQAIQEDIREKNPDFVF
                     IGITSPKKEYIIQKFMDSGVNSVFMGVGGSFDVLSGHIQRAPLWMQKSNLEWLFRVAN
                     EPKRLFKRYFVGNISFIGRVLKAKRGVKY"
     gene            5894..6718
                     /locus_tag="ACHBV5_001659"
     CDS             5894..6718
                     /locus_tag="ACHBV5_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HFM9967423.1"
                     /translation="MNQTEMIRLIQKVELDAIKEFKKICEENDIDFFLRGGSVLGAVK
                     YDGFIPWDDDMDIAVPREAYDKLPSVFKDRIIAGKYQVLTYQYCDTLHCYFPRLFLLE
                     DERKRLGLPRNTNLGLHLIDIIPLDGAPNHSVLRKIYFGKVYWYRFLASLGTTYVGDH
                     VDMHSTKQKLIIGFFKKLGFAKLFPQNSVYRRLDNLYKKYDWKKQKYAGTINASLFAK
                     EVMPVEIWGEGVEKPFEDTFFKVPTEYDRYLKRLYGENYLYEEPSDDEKKSHLGGH"
     gene            6720..7598
                     /locus_tag="ACHBV5_001660"
     CDS             6720..7598
                     /locus_tag="ACHBV5_001660"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFM9967424.1"
                     /translation="MFCYIILHYKVLEETISCVKSIKEGNYNAKQIVIIDNFSNNGTG
                     EKLQELYESDLEIDVLINHENAGFARGNNVAYQFAKEKYNPDFMVIMNNDIEIETENF
                     EKIVTDIYREEKFHLLGPDIFSTTYQLHQNPKRLTHYTYGEVKALNEKFKKGSQVSLA
                     LKIKCWLKASKVLRTAIYQNRRKKGSVDYRKQVENPILHGSFIVYSRDFIEKEEYAFN
                     PNTFFYYETEILDYEAELKGYKRIYTPKIRVLHHQNVATNQVYTNLLEKTLFSNKCNF
                     KSTSYFLKLMKENEDV"
     gene            7599..8936
                     /locus_tag="ACHBV5_001661"
     CDS             7599..8936
                     /locus_tag="ACHBV5_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008755 - O antigen polymerase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="HFM9967425.1"
                     /translation="MSYLFLLCLTLFLLTIFYFFAFIQDLIAPPVVMSVMFLISSVFA
                     LVNSKNWNIEYSGIAYILIISGIIIFSLPLMALKSPNFNTEVKIADRLIDIQFWKIAL
                     TIIIDLFILYLYRKEIYNLVLSNGYTGSNIQWFFRNATSYEGELTVRTFIRVLIRVID
                     VSAYIFGYTFINNFLIYRHKRPKDILLLVPLLIFISKTLISGGRQDIIKILIAYVIMM
                     YIQQKRKVGWNRVISHKYIHLGFVGLIAGIPAFYYSLFLAGRSTTRTLFESVSTYLGG
                     SIQHFNQYIENPLDPGEVFGSETLVPILNILGEMGLVNYRSTIHLEFRTLGVTVGNVY
                     TFFRRPLHDFGLVGMYVFVFAVGAFFAIYYLVLRKKQVGFNLDIHTIIYSYVFYWIFL
                     SSIEQYSFTMISLYTLVFIVLVYFMAIFYWCTDFKRGKLIFKISDSSIKLKEE"
     gene            8959..10380
                     /locus_tag="ACHBV5_001662"
     CDS             8959..10380
                     /locus_tag="ACHBV5_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967426.1"
                     /translation="MNTKIKNIITSFSYVISSNLLIVLTSSLVVLIFPKIMGVTEYSY
                     WQLYIFYLTYIGFFHLGWIDGIYLKYGGLEYTNLDRKQFYSQMILFSSFLMLISLVLF
                     TLNLITVRDENARYIYNMAIISMIVTNLRTLYVYILQMTNRLKDSSVILISDRVLYVL
                     LLFMFIVFGWHEYKVMIWADILGRTFSLMLSFWICKDIVFQPLSKFILDFKESLDNIR
                     VGINLMLSNIASSMIIGIVRMGIQWNWNIETFGKVSLTLSISNLLMTFINAIGLVIFP
                     LIKRTKTENLPKIYSNLRNALMLVMFAILLFYYPLKFILDIWLPAYKDALVFMALIFP
                     MSVYEGKMALVINTYLKAMRMEKDILKINALVMLTSMVVTLVTTLLLNNLGLTVVSIV
                     ILLALRSIIAELILSKKLKISVKQDIALELLMTIIFISSSWYLSIWIAVIIYLLAYTL
                     YLYLKHKDIRMYIEYFKNHKKIS"
     gene            10444..11532
                     /gene="wecB"
                     /locus_tag="ACHBV5_001663"
     CDS             10444..11532
                     /gene="wecB"
                     /locus_tag="ACHBV5_001663"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-hydrolyzing UDP-N-acetylglucosamine
                     2-epimerase"
                     /protein_id="HFM9967427.1"
                     /translation="MKKIMLVFGTRPEAIKMCSLVNELRKQEDMKTVVCVTGQHKEMV
                     SPVLDLFGVQPDYDLEIMKANQNLFSITISILEKIKPVLEKEQPDIVLVHGDTTTTYA
                     AALAAFYLGIKVGHVEAGLRTYNLQSPFPEEFNRQSTSIIANYHFAPTELAKENLIKE
                     GRNNIYVTGNTVIDALTTTVQKDYTHPDLDLNDGNRLILLTAHRRENLGEPMRHMFRA
                     VKRVLNEYDDVKVIYPIHKNPLVRETATEIFGDTERIQIIEPLDVLDFHNFMNHSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVAAGTLKLVGTDEETIYQNFKMLLDDPE
                     EYKKMSQASNPYGNGDASKQIVRILRGI"
     gene            11571..12440
                     /gene="rfbA"
                     /locus_tag="ACHBV5_001664"
     CDS             11571..12440
                     /gene="rfbA"
                     /locus_tag="ACHBV5_001664"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFM9967428.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGLKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKN
                     EYGQYLLRLIGEA"
     gene            12441..13037
                     /locus_tag="ACHBV5_001665"
     CDS             12441..13037
                     /locus_tag="ACHBV5_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HFM9967429.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDLE"
     gene            13047..14096
                     /gene="rfbB"
                     /locus_tag="ACHBV5_001666"
     CDS             13047..14096
                     /gene="rfbB"
                     /locus_tag="ACHBV5_001666"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFM9967430.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            14162..15013
                     /gene="rfbD"
                     /locus_tag="ACHBV5_001667"
     CDS             14162..15013
                     /gene="rfbD"
                     /locus_tag="ACHBV5_001667"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFM9967431.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVARASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            15110..16156
                     /locus_tag="ACHBV5_001668"
                     /pseudo
     CDS             15110..16156
                     /locus_tag="ACHBV5_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251597.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5179 a         2487 c         3336 g         5154 t
ORIGIN      
        1 tttttcgttt cattcatatt cagttggatc cttttcatat gactattcta ccaaatggga
       61 cattttcacg ttcgatttac taaagacatt atcacattcg aattacatta aagatgcaga
      121 tagtaaaaaa aatgtagaca ttaccgtaaa aaagtgatat aatcgtatga tgttcaaggt
      181 ataggtgtta atcatgagta gacgttttaa aaaatcacgt tcacagaaag tgaagcgaag
      241 tgttaatatc gttttgctga ctatttattt attgttagtt tgttttttat tgttcttaat
      301 ctttaagtac aatatccttg cttttagata tcttaaccta gtgataactg cgttagtcct
      361 actagttgcc ttgctagggc tactcttgat tatctataaa aaagctgaaa agtttactat
      421 ttttctgttg gtgttctcta tccttgtcag ctctgtgtcg ctctttgcag tacagcagtt
      481 tgttggactg actaatcgtt taaatgcgac ttctaattac tcagaatatt caatcagtgt
      541 cgctgtttta gcagatagtg atatcgaaaa tgttacgcaa ctgacgagtg tgacagcacc
      601 gactgggact gataatgaaa atattcaaaa actactagct gatattaagt caagtcagaa
      661 taccgatttg acggtcaacc agagttcgtc ttacttggca gtttacaaga gtttgattgc
      721 aggggagact aaggccattg tcctaaatag tgtctttgaa aacatcatcg agtcagagta
      781 tccagactac gcatcgaaga taaaaaagat ttataccaag ggattcacta aaaaagtaga
      841 agctcctaag acgtctaaga atcagtcttt caatatctat gttagtggaa ttgacaccta
      901 tggtcctatt agttcggtgt cgcgatcaga tgtcaatatc ctgatgactg tcaatcgaga
      961 taccaagaaa atcctcttga ccacaacgcc acgtgatgcc tatgtaccaa tcgcagatgg
     1021 tggaaataat caaaaagata aattaaccca tgcaggcatt tatggagttg attcgtccat
     1081 tcacacctta gaaaatctct atggagtgga tatcaattac tatgtgcgat tgaacttcac
     1141 ttctttcttg aaaatgattg acttattggg aggggtagat gttcataatg atcaagagtt
     1201 ttcagctcta catgggaagt tccatttccc agtagggaat gtccacctag actctgagca
     1261 ggctctaggt tttgtacgtg aacgctactc actagccgat ggagaccgtg atcgtggtcg
     1321 caaccaacaa aaggtcattg tagcaattat tcagaagtta acttctacag aggttttgaa
     1381 aaactatagt agtattcttc aaggattgca ggattctctt caaacaaata tgccgattga
     1441 gactatgata gatttagtga atactcagtt ggaaagtggg gggaattata aagtaaattc
     1501 tcaagattta aaagggacag gtcggatgga tcttccttct tatgcaatgc cagacagtaa
     1561 cctctatgtg atggaaatag atgatagtag tttagctgta gttaaagcag ctatacagga
     1621 tgtgatggag ggtagatgaa atgatagaca tccattcgca tatcgttttt gatgtagatg
     1681 acggtcccaa gtcaagagag gaaagcaagg ctctcttggc agaatcctac aggcaggggg
     1741 tgcgaaccat tgtctctacc tctcaccgtc gcaagggcat gtttgaaact ccggaagaga
     1801 agatagcaga aaactttctt caggttcggg aaattgcaaa agaagtggca gatgatttag
     1861 tcattgctta tggcgcagag atatactata ctctggatgc tctagaaaag ctagaaaaaa
     1921 aagaaattcc tacccttaat gatagtcgtt atgccttgat tgagtttagc atgcatactt
     1981 cctatcgtca gattcatacg ggattgagca atattttgat gttgggaatc acgccagtaa
     2041 ttgctcatat tgaacgttat gatgctttag agaataacga aaaacgtgtt cgtgaactga
     2101 ttgatatggg gtgctatact cagataaata gttatcatgt ttcaaaacct aagttctttg
     2161 gtgaaaaata taaattcatg aaaaagagag ctcggtattt tttggaacgt gatttagttc
     2221 atgtagttgc aagtgacatg cacaatttag acagtagacc tccatatatg caacaggcat
     2281 atgatatcat tgctaagaaa tatggagcga aaaaagtaaa agaacttttt gtagataatc
     2341 ccagaaaaat tataatggat caattaattt aggagaaaat atgaaggaac aaaacacttt
     2401 ggaaatcgat gtattgcaac tattcagagc tttatggaaa agaaagttgg tcattttatt
     2461 agtggcaatt ataacttctt cagttgcttt tgcctacagt acttttgtta tcaaacctga
     2521 gtttactagt atgactcgga tttatgtagt taaccgtaat cagggagaga agtctggttt
     2581 aaccaatcaa gacttgcagg caggatcatc cttggttaaa gactatcgtg aaattatcct
     2641 atcgcaggat gttttggagg aagttgtttc tgatttgaaa ctagatttga cgccaaaaga
     2701 tttggctaat aaaattaaag taacagtacc agttgatacc cgtattgtct ctgtttcagt
     2761 tagtgatcga gttcctgaag aggcaagccg tatcgctaac tctttgagag aagtagctgc
     2821 tcaaaaaatt atcagtatta ctcgtgtttc tgatgtgaca acactggagg aggcaagacc
     2881 ggcgacatca ccgtcttcgc caaatattaa acgcagtaca ctaattggtt ttttggcagg
     2941 agtgattgga actagtgtta tagttcttat tcttgaactt ttggacactc gtgtgaaacg
     3001 tccgaaagat atcgaagata cactgcatat gacacttttg ggaattgtac caaacttgaa
     3061 taagttgaaa taggagagag gaatgccgac attagaaata gcacaaaaaa aactggagtt
     3121 cgttaagaag gcagaagaat attacaatgc cttgtgtaca aatatacagt tgagcggaga
     3181 taaactaaaa gtaatttccg ttacttctgt taaccctgag gaaggaaaaa caactacttc
     3241 cgtaaatata gcaaggtcgt ttgcgcgtgc aggctataaa actcttttga tcgatggcga
     3301 tactcgaaat tcagttatgt caggattttt taaatctcgt gaaaaaatta cagggctaac
     3361 ggaattttta tctgggacag ctgatttatc tcacggttta tgtgatacaa atattgaaaa
     3421 tttatttgta gttcaatcgg gcactgtatc accaaaccct acagccttgt tacaaagtaa
     3481 aaattttaat gatatgattg aaacattgcg taaatatttt gattatatca ttgttgatac
     3541 agcacctatt ggaattgtta ttgatgcggc aattatcact caaaagtgtg atgcgtccat
     3601 cttggtaaca gcaacaggtg aggtgaataa acgtgatgtc caaaaagcga aacaacaatt
     3661 agaacaaaca gggaaactgt tcctaggagt tgttttgaat aaattagata tctcggttga
     3721 taagtatgga gtttacggtt tctatggaaa ttatggtaaa aaaataattt aggaaagatt
     3781 ctatggatga aaaaggattg aaaatttttt tggcagtatt acagagtatt attgtcattt
     3841 tattggttta ttttcttagc tttgttagag agacagaact tgaacgttct tcgatggtta
     3901 tactatacct tctccacttt tttgtattct attttagttc ctatggtaac aattttttta
     3961 aaagagggta cctagttgag tttaatagta ccataagata tatttttttc tttgcaatag
     4021 ctataagtgt attaaacttt tttatagcgg aacggtttag tatctctaga agaggaatgg
     4081 tatacttctt aactttagaa ggaatatcct tatacttgtt aaatttctta gtaaagaaat
     4141 attggaagca tgtgtttttt aatctaaaaa atagcaagaa aattttactg ttaacagtaa
     4201 cgaaaaatat ggaaaaagtt cttgataaat tgctagaatc tgatgaactt tcatggaaat
     4261 tggtagcagt aagtgttttg gataaatctg attttcaaca tgataaaata cctgtaattg
     4321 aaaaggaaaa aattattgaa tttgcaacgc atgaagttgt ggatgaggtg tttgtcaatc
     4381 ttccaggaga gagctacgat attggagaaa ttatctctag gtttgagaca atggggatag
     4441 atgtaactgt aaatcttaaa gcatttgata agaatttggg tcgcaataaa caaattcatg
     4501 agatggtagg attgaatgta gtcactttct ctacaaattt ttataaaact agtcatgtaa
     4561 ttgctaagcg gattattgat atcatgggtg cattggtagg gctgatacta tgtggtttag
     4621 tcagtattgt attggttcct ttgattcgaa aggatggggg ctctgctatt tttgctcaga
     4681 cgcgtatagg aaaaaatggt cgtcagttca ctttttataa gtttcgctct atgtgtgtag
     4741 atgccgaggc gaaaaaaaga gaactcatgg aacaaaatac catgcagggt ggaatgttta
     4801 aggtggacga tgatcctcgt atcacgaaaa ttggtcgttt tatacggaag actagcttgg
     4861 acgagttacc acagttttat aatgttctaa agggagatat gagtttggtt ggcacacggc
     4921 cacctacagt ggacgagtat gttcagtata cttcagaaca gaaacgtcga ctcagcttta
     4981 aacctggtat tacaggttta tggcaggtta gcggccgtag taaaataacc gattttgacg
     5041 atgttgtaaa attagatgtg gcttatattg ataattggac aatctggaaa gatattgaaa
     5101 ttttgcttaa aactgttaaa gttgtattta tgagagatgg agcgaagtga ggaatgaggg
     5161 atagaatcca acttttaggt gtaacaattg atttgcttac gatgaatgaa acgatagata
     5221 ttgtagaaca atatgtatta gaaaaaagac cactacactt gatgggggtg aatgctgata
     5281 aaattaatca gtgtcataca gatgagaaaa tcaaaaaaat cgttaatgag tcaggaatca
     5341 ttaatgcgga tggagcatca gttgttcttg caagtaagtt tttaggaacg cctgttcctg
     5401 aacgagtagc gggtattgat ttgatgcaat gtcttttaga gttgtcaaat aaaaaaggat
     5461 attcagttta cttttttgga gcaaaagaag aagttttgca agatatgctc aaagtattta
     5521 agagagatta tccaaatttg atagttattg gacacagaaa tggctatttt tctgaagagg
     5581 atgaacaagc tattcaagaa gatattcgtg aaaagaaccc tgattttgtg tttattggaa
     5641 ttacgtctcc taaaaaagaa tatattattc aaaaatttat ggatagtggc gtcaattcgg
     5701 tatttatggg agttggcggt agttttgatg tcttgtctgg tcatatccaa cgagcacctc
     5761 tatggatgca aaagtcaaat ttagagtggt tattccgtgt agctaatgag cctaaacgtc
     5821 tctttaaacg ttattttgta gggaatattt cattcatagg aagagtttta aaagcaaaaa
     5881 gaggtgtaaa atattgaacc agacagagat gattcgctta attcaaaaag ttgaattaga
     5941 tgctataaaa gagtttaaaa aaatctgtga agagaatgat atagattttt tcctccgcgg
     6001 tggtagtgta cttggtgcgg tcaaatacga cggctttatt ccatgggatg atgatatgga
     6061 tatcgctgtc cctcgtgaag catacgacaa acttccaagt gttttcaaag atagaattat
     6121 cgctgggaaa tatcaggttc ttacttatca atactgtgat acgttgcatt gctactttcc
     6181 tcgactattc cttttagaag atgaaagaaa acgtttgggc ttgccacgaa ataccaatct
     6241 aggattgcat ttgattgata tcattccttt agatggagca ccaaatcatt cggttttaag
     6301 aaagatttac tttggcaaag tatactggta tcgtttttta gcaagtttag gaacaactta
     6361 tgttggcgac catgtggata tgcattccac taagcaaaaa ctaattattg gtttctttaa
     6421 aaaactagga tttgcaaaac tatttcctca aaattctgta tacagacgct tggataatct
     6481 ctataaaaag tatgattgga aaaagcagaa gtatgcgggg actatcaatg cttctttatt
     6541 tgctaaagaa gttatgccag tagagatttg gggagaagga gtagagaagc cttttgagga
     6601 tactttcttt aaagttccaa cggagtatga tcgctacctg aaaagacttt acggagaaaa
     6661 ctatctttac gaagagccta gtgatgatga aaagaaatcg catttaggag gacactaatt
     6721 tgttttgtta tattattttg cattacaaag tcttagaaga aactatttct tgtgttaaat
     6781 ctataaaaga aggcaattat aatgcaaagc aaatcgttat tattgataat ttttctaata
     6841 atggtactgg tgaaaaacta caagagcttt atgaatcaga tttagaaatt gatgttttga
     6901 ttaaccatga aaatgctggt tttgctcgtg gaaataatgt ggcttatcaa tttgctaagg
     6961 aaaagtataa ccccgatttc atggttatca tgaataacga tattgagata gaaacagaaa
     7021 attttgaaaa aattgtgaca gatatctatc gtgaggaaaa attccatttg ctcgggccag
     7081 atatcttctc gactacttac caacttcacc aaaacccaaa acggttgaca cattatactt
     7141 atggagaagt taaagctcta aatgaaaaat ttaaaaaagg gagccaagtt agtctagctt
     7201 taaaaatcaa atgttggttg aaagctagta aagttcttcg aacagcaatc tatcaaaata
     7261 gacgtaaaaa aggatcagta gactatagaa aacaggtaga aaacccaatt cttcatggtt
     7321 cttttattgt atattcgaga gattttatcg aaaaagagga gtatgctttt aaccctaaca
     7381 ccttcttcta ctatgaaaca gagatattag attatgaagc tgaattaaaa ggatacaaga
     7441 gaatttatac acctaaaatt agagttttgc accatcaaaa tgttgcaact aatcaagttt
     7501 acacgaactt gttagaaaaa accttgtttt caaataaatg caactttaaa tccaccagtt
     7561 attttttgaa gttgatgaaa gaaaacgagg atgtttaaat gagttattta tttttacttt
     7621 gccttacatt attcttattg actatattct atttctttgc ttttattcaa gatttaattg
     7681 ctcctccagt agttatgtct gtaatgtttc taattagttc agtatttgca ctggttaatt
     7741 caaaaaactg gaatattgaa tatagtggaa tagcctatat tctcataatt agtggtatta
     7801 ttatattttc gcttccttta atggcattaa aatcacctaa ttttaatact gaggttaaga
     7861 ttgctgatcg attaattgat atccaatttt ggaaaattgc tctaactatt ataattgatc
     7921 tctttatttt gtatctttac aggaaggaaa tatataacct tgttcttagt aatggatata
     7981 cggggtcaaa tattcagtgg ttttttagaa atgcaacgag ttatgaaggt gaattgacag
     8041 tgcgaacttt tattcgagtt ctcattcgtg ttattgacgt atctgcttat atttttggat
     8101 atacttttat taataatttt cttatctatc gccataaacg ccctaaagac atattacttt
     8161 tagtaccttt attaatattt atttcaaaaa ctttaatatc aggaggccgg caagatatta
     8221 ttaaaattct gattgcctat gtaatcatga tgtatatcca acaaaaacgg aaagttggat
     8281 ggaatagagt catatctcat aaatatattc accttggatt tgttggttta atagcaggta
     8341 ttccagcatt ttactactct ttgtttttag ccggtcgttc aacgactagg acgctatttg
     8401 agagtgtttc gacctatcta ggaggctcaa ttcagcattt taatcagtat attgaaaatc
     8461 cattagatcc tggtgaagtt tttggcagtg aaacattggt gcctatatta aatatattag
     8521 gggaaatggg cctagttaat tatcgtagta caattcattt agaatttcgg acactaggag
     8581 ttactgtagg aaatgtttat acttttttta gaagaccctt gcatgatttt ggtctagttg
     8641 gtatgtatgt gtttgtcttt gctgtaggtg ctttttttgc tatttattat ttagttctga
     8701 gaaagaaaca ggttggtttt aatttggata ttcataccat tatttattct tatgtctttt
     8761 attggatttt tttatcatca atcgagcaat actcgttcac aatgattagt ctatatacac
     8821 ttgtatttat tgtgttggtt tactttatgg ctatctttta ctggtgtaca gattttaaaa
     8881 gaggaaaact gatttttaaa atttctgact caagtatcaa attaaaagaa gaataacaga
     8941 atgtatagga gagggtagat gaatactaaa attaaaaata taataactag tttttcttat
     9001 gttatttctt caaatctgct catagtttta acctcatcac tagttgtttt gatttttcct
     9061 aaaataatgg gggtaactga gtacagttac tggcaacttt atatttttta tctgacctat
     9121 atcggttttt tccacttggg ttggattgat gggatttatc tcaaatatgg tggcttagaa
     9181 tatacaaatt tagatagaaa acagttttat tctcagatga ttctattttc tagtttctta
     9241 atgctaatct cgctggtatt atttactttg aacctaataa ctgtaaggga tgaaaacgca
     9301 agatatattt ataatatggc tatcattagc atgatagtca caaacttaag aacactctat
     9361 gtttatatct tgcagatgac aaatcgcttg aaggatagtt cagtcattct aattagtgat
     9421 cgcgttttat atgtactcct tttattcatg tttattgtat ttggatggca tgagtacaag
     9481 gtcatgattt gggctgatat tctaggtcga acattttctc tcatgctttc cttctggatt
     9541 tgtaaagata ttgtgtttca gcctttgtca aaatttatct tagatttcaa ggagtccctt
     9601 gataatatcc gtgttggaat caatttaatg ctatctaaca ttgcgagtag catgattata
     9661 ggcattgttc gtatgggaat tcaatggaat tggaatattg aaacattcgg gaaagtgtca
     9721 ttaactttga gtatatctaa tttattaatg acttttatta atgccattgg attagttatc
     9781 tttcctttga taaagcgaac aaagactgag aatttaccta aaatttattc taatttaaga
     9841 aatgctttga tgttggttat gttcgcaatc ttgctcttct actatccttt aaaatttatt
     9901 cttgatattt ggcttcctgc ttataaggat gccttagttt tcatggccct aatttttcct
     9961 atgtcagttt atgaagggaa aatggctttg gtgataaata catatttaaa agcaatgaga
    10021 atggaaaaag acattctcaa aattaatgct ttggttatgt taactagtat ggtagtgaca
    10081 ttagtgacta ctctactact aaataatttg gggctgacag ttgtatctat agttatttta
    10141 cttgctttaa gaagtataat agctgaatta attttatcca aaaaactgaa gatatcagtc
    10201 aagcaagaca ttgctttaga gttacttatg acgattatat ttatttcttc aagttggtat
    10261 ctctctattt ggattgcagt aataatttat ttattggcgt atactttata tttgtattta
    10321 aagcacaaag atatcagaat gtatatagaa tactttaaaa atcataaaaa aatatcataa
    10381 aaattatata tcaatgaaat ggtagattac atttctacct ttttatccat ttaggaggaa
    10441 acgatgaaaa agataatgct agttttcggt acacgtccag aagcaataaa aatgtgttca
    10501 ttagtcaatg agttgagaaa acaggaagat atgaaaacag ttgtttgtgt aactggtcaa
    10561 cacaaggaga tggttagccc tgttttagat ttatttggag ttcaaccaga ctatgattta
    10621 gaaattatga aggctaatca aaacttgttc tctataacaa taagtatttt agaaaaaata
    10681 aaacctgtgt tagaaaaaga acaaccagat attgttttgg ttcacggtga tactactacg
    10741 acatatgcag cagctttagc ggcattttat ctaggaatta aagttggtca tgttgaagct
    10801 ggattacgaa cttacaacct gcaaagtcct ttcccagaag agttcaacag acaatcgact
    10861 tctattattg caaattatca ttttgctcct acagaattag ctaaagaaaa tctaataaaa
    10921 gagggtagaa ataatatcta tgttactgga aatacagtga ttgatgcact tacaactaca
    10981 gtacaaaagg attatacaca ccccgatcta gatttaaacg atggaaatcg cctcatctta
    11041 ttgactgctc atagacgcga aaatctcgga gaacctatga gacatatgtt tagagctgtt
    11101 aaacgagttt taaatgaata tgacgatgtt aaagtaattt atccaattca taaaaatcca
    11161 ttggtacggg aaacagctac agaaattttt ggagatacag aacgtattca gatcattgaa
    11221 cctttagatg ttcttgattt tcacaacttt atgaatcata gttatatgat tctaactgac
    11281 tcaggagggg ttcaagaaga ggcaccttcg ttaggaaagc ctgtattggt catgcgagat
    11341 acgacagaaa gacctgaagg agtagctgct ggaacgttga aattggttgg gactgatgag
    11401 gagactattt atcaaaactt taagatgctt ttagacgatc ccgaagaata taaaaaaatg
    11461 agtcaagcta gtaatcctta tggaaatggt gatgctagta aacagattgt tcgaatttta
    11521 cgtggaattt gagtgtgttc agataaagta atatagaaag gtaccctact atgaaaggta
    11581 ttattctagc aggtggttcg gggacacgtt tatatccttt gactcgcgct gcatcaaaac
    11641 aacttatgcc ggtttatgat aaaccgatga tttactaccc actttcaaca ttgatgttgg
    11701 ctgggattag ggatattttg attatttcca ctccacagga tttacatcga ttccaagagc
    11761 ttcttcaaga cggatctgag tttgggctca aactttctta tgcagagcaa ccaagtccag
    11821 atggtttggc acaagccttt atcattgggg aagagtttat ttctgatgat agcgttgcgc
    11881 tgatcttagg tgacaatatc tatcacggtt ctgggctttc caagatgcta caaaaggcag
    11941 cgagtaagga gtcgggagca actgtttttg gctaccatgt caaggatcca gagcgctttg
    12001 gtgtggttga gtttgatcag gatatgaagg ctatttctat tgaagaaaag ccagagcaac
    12061 ctcgttcaaa ctatgcagtt acaggtctct atttctatga taatgatgta gtagagattg
    12121 ccaagagtat taaaccaagt cctcgtggtg aactggaaat tacagatgta aacaaggctt
    12181 acctagatcg tggtgatttg tctgttgagc ttatgggacg tggctttgct tggctggata
    12241 ctggaactca tgaaagttta ctagaggctt cacagtacat cgaaacagtg caacggatgc
    12301 aaaatgttca ggtagcaaac ttagaagaaa ttgcttaccg tatgggctat atcagtcgag
    12361 aagatgtatt ggccttagcc caaccactta agaaaaatga atacggacag tatctgctcc
    12421 gtttgattgg agaagcatag atgacagata attttttcgg taagacgctt gcggcacgca
    12481 aggttgaagc tattccaggc atgttggagt ttgatatccc cgttcatgga gataatcgtg
    12541 gctggtttaa agaaaatttc caaaaggaaa aaatgcttcc acttggattt ccagagtctt
    12601 tctttgcaga aggaaaattg caaaacaatg tatccttctc acgtaaaaat gtccttcgag
    12661 gtctccacgc agagccttgg gataagtaca tctctgtagc agatggaggg aaagttctgg
    12721 gttcttgggt tgatctacgc gagggtgaaa cctttgggaa tacctatcag acagtgattg
    12781 atgcgagtaa gggaatcttt gttcctcgag gcgtagctaa tggctttcaa gttttatcag
    12841 atacagtgtc atatagctat ctggtcaatg attactgggc tcttgaactc aaacccaagt
    12901 atgcctttgt gaactacgct gatccaagcc ttggtattga atgggaaaat attgcagaag
    12961 cagaggtttc agaagcagac aaacatcatc cactacttaa ggatgtaaaa cctttgaaaa
    13021 aagaagattt ggaataagga aagaatatga ctgaatacaa aaatattatc gtgacaggtg
    13081 gagctggctt tatcggttct aactttgtcc attatgttta cgagaacttt ccagatgttc
    13141 atgtgacagt cctagataag ttgacttatg ctggaaaccg cgcgaatatt gaggaaattt
    13201 taggtaatcg tgttgagtta gttgttggtg acattgctga tgcggagttg gtagacaagt
    13261 tggctgctca agcagatgct atcgttcatt atgcagcgga aagccacaat gataattcgc
    13321 tcaatgatcc atcgccattt attcatacta acttcatcgg aacctatact cttttagaag
    13381 ctgctcgtaa gtatgatatt cgcttccacc atgtatcgac agatgaagtt tatggggatc
    13441 tccctttacg cgaagatttg ccaggtcatg gtgaaggacc aggtgagaaa tttactgctg
    13501 aaacaaaata caacccaagc tctccgtact catcaaccaa ggcagcctca gatttgattg
    13561 tcaaagcctg ggtgcgttct tttggagtca aggcaacgat ttccaactgt tcaaataact
    13621 acggtcctta tcaacatatc gaaaaattca tcccacgtca gattactaac atcctaagtg
    13681 gtatcaagcc aaaactttac ggtgaaggta agaacgttcg tgattggatt cataccaatg
    13741 accattcttc aggagtttgg acaatcttga caaaagggca aatcggtgaa acctacttga
    13801 ttggggctga tggtgagaag aacaataagg aagttttgga acttatcctt aaggaaatgg
    13861 gacaagctgc ggatgcctat gatcatgtga ctgaccgtgc aggacatgac cttcgctatg
    13921 cgattgatgc tagcaagctc cgtgatgagt tggggtggaa acctgaattt accaactttg
    13981 aagctgggct caaggcaaca atcaagtggt atacagataa ccaagaatgg tggaaagcag
    14041 agaaagaagc tgttgaagcc aattatgcta agactcagga gattattaca gtataaaaag
    14101 caggaaatag ctgcttttta ttgctatatt gggaagagtt acatattaga aaggtctaga
    14161 gatgatttta attacagggg caaatggcca attaggaacg gaacttcgct atttattgga
    14221 tgaacgtaat gaagaatacg tggcagtaga tgtggctgag atggacatta ccgatgcaga
    14281 aatggttgag aaagtttttg aagaggtgaa accgacttta gtctaccact gtgcagccta
    14341 caccgctgtt gatgcagcag aggatgaagg aaaagagttg gacttcgcca tcaatgtgac
    14401 ggggacaaaa aatgtcgcaa gagcatctga aaagcatggt gcaactctag tttatatttc
    14461 tacggactat gtctttgacg gtaagaaacc agttggacaa gagtgggaag ttgatgaccg
    14521 accagatcca cagacagaat atggacgcac taagcgtatg ggggaagagt tagttgagaa
    14581 gcatgtgtct aatttctata ttatccgtac tgcctgggta tttggaaatt atggcaaaaa
    14641 cttcgttttt accatgcaaa atcttgcgaa aactcataag actttaacag ttgtaaatga
    14701 ccagtacggt cgtccgactt ggactcgtac cttggctgag ttcatgacct acctagctga
    14761 aaatcgtaag gaatttggtt attatcattt gtcaaatgat gcgacagaag acacaacatg
    14821 gtatgatttt gcagttgaaa ttttgaaaga tacagatgtc gaagtcaagc cagtagattc
    14881 cagtcaattt ccagccaaag ctaaacgtcc gctaaactca acgatgagcc tggccaaagc
    14941 caaagctact ggatttgtta ttccaacttg gcaagatgca ttgcaagaat tttacaaaca
    15001 agaagtgaga taagtagtag aatgattttc tagtctaata aaagaggcag ataatgaact
    15061 ccaaaggagc ttaagatgta cgattatctt gttgttggtg ctggtctctt tggcgcatag
    15121 ctttggctca gtttctatta tcgctcacac catccatcag aagtttaatc tgaaggtacc
    15181 caattatcgc caagaagaag attgggctag gatgggttta ccaatcacac gtaaggaaat
    15241 ctctaattgg catatcaagg caagtcaata ctatttagag tccctttata accttttacg
    15301 agaaaagttg ttagaacaac ctcttcttca tgcggatgaa acctcttatc gggtcttaga
    15361 aagtgatagt cagctgacct actattggac ctttttgtct gggaaagctg agaatcaagt
    15421 aatcacgctt taccaccatg atcagtgtcg gagtggttcg gtagtgcaag aattcctagg
    15481 agattattct ggctatgtgc attgtgatat gttgcggcag taacttagga ctttagtcct
    15541 ctagttctgt ctatgcgata gcagtccaag gtttaggagc aaggcgacgc taagcttggt
    15601 aaactgcgaa ccgctagaag cttatcgtca actggaagaa gctgaacttg ttggatgttg
    15661 ggcgcatgtg agaaggaaat tttttgaagt gccccccaag caagcagata aatcatcctt
    15721 aggagctaaa ggtttagctt attgtgatca gttattttcc ttggaaagag actgggaggc
    15781 tttgccagct gatgaacgac tacagaaacg tcaagaacat ctccaacccc taatggaaga
    15841 cttctttgct tagtgccgtc gtcagtcagt tttatcgggt tcaaaactag gaagggcaat
    15901 tgaatacagc ctcaagtatg aagaaacctt taagaccatt ttaaaagacg gacatctggt
    15961 cctttccaat aatctagctg aacgcgccat taaatcattg gttatgggac ggagtaaaag
    16021 agtccagtgg actcttttag cctaagctaa attttaaaaa gcgagggtgg ttattttctc
    16081 aaagttttga aggagctaaa gcaagagcta ttattatgag cttattggaa acagctaaac
    16141 gtcatcaact aaatag
//
LOCUS       DAYYYC010000049        15392 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.049, whole genome shotgun sequence.
ACCESSION   DAYYYC010000049 DAYYYC010000000
VERSION     DAYYYC010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15392
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.049"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            1..656
                     /locus_tag="ACHBV5_001669"
                     /pseudo
     CDS             1..656
                     /locus_tag="ACHBV5_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(720..1802)
                     /locus_tag="ACHBV5_001670"
     CDS             complement(720..1802)
                     /locus_tag="ACHBV5_001670"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFM9967432.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(1799..2776)
                     /locus_tag="ACHBV5_001671"
     CDS             complement(1799..2776)
                     /locus_tag="ACHBV5_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFM9967433.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            2997..3365
                     /locus_tag="ACHBV5_001672"
                     /pseudo
     CDS             2997..3365
                     /locus_tag="ACHBV5_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603343.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            3603..4994
                     /gene="pgdA"
                     /locus_tag="ACHBV5_001673"
     CDS             3603..4994
                     /gene="pgdA"
                     /locus_tag="ACHBV5_001673"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HFM9967434.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            5108..5950
                     /locus_tag="ACHBV5_001674"
     CDS             5108..5950
                     /locus_tag="ACHBV5_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFM9967435.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERENLKTIAVQSGAPRVD
                     DVDF"
     gene            6223..6984
                     /locus_tag="ACHBV5_001675"
     CDS             6223..6984
                     /locus_tag="ACHBV5_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFM9967436.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            7177..8094
                     /gene="glyQ"
                     /locus_tag="ACHBV5_001676"
     CDS             7177..8094
                     /gene="glyQ"
                     /locus_tag="ACHBV5_001676"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFM9967437.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            8306..10342
                     /gene="glyS"
                     /locus_tag="ACHBV5_001677"
     CDS             8306..10342
                     /gene="glyS"
                     /locus_tag="ACHBV5_001677"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFM9967438.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            10384..10641
                     /locus_tag="ACHBV5_001678"
     CDS             10384..10641
                     /locus_tag="ACHBV5_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFM9967439.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(10864..12108)
                     /locus_tag="ACHBV5_001679"
     CDS             complement(10864..12108)
                     /locus_tag="ACHBV5_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFM9967440.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AFTGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNVNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(12127..12732)
                     /locus_tag="ACHBV5_001680"
     CDS             complement(12127..12732)
                     /locus_tag="ACHBV5_001680"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFM9967441.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            complement(12792..13715)
                     /locus_tag="ACHBV5_001681"
     CDS             complement(12792..13715)
                     /locus_tag="ACHBV5_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFM9967442.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            14009..15388
                     /gene="nox"
                     /locus_tag="ACHBV5_001682"
     CDS             14009..15388
                     /gene="nox"
                     /locus_tag="ACHBV5_001682"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HFM9967443.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALAGGKIELFRNGAF
                     LVDKKQETSIPDVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
BASE COUNT         4705 a         2816 c         3359 g         4512 t
ORIGIN      
        1 ccatggttgg cgaaatatta tgccacgtcc agaacatcct aggaaagcag acgctcaaac
       61 cattgtcgcg tctaaaaata aaatctcaat tcaagaagac aagaaagcgc tttaaaacca
      121 gtagaccttt tcataaggtt cgcttgatgt accaagatga ggctggtttc ggtagaatca
      181 gtaaactggg atcttgttgg tctccaatag gagtaggtcc acatgtccat agtcactata
      241 tacgagaatt tcgctattgt tatggagctg ttgatgcccc atacaggcga atcatttttc
      301 ttaatagctg gtggatgtaa tactgagtgg atgaacgtct ttttagaaga gctttcacaa
      361 gcttatccag atgattattt tttactcgtt atggacaatg ctatatggca taaatcaagt
      421 accttaaaga ttccgactaa tattgatttt acctttattc ctccatacac accagagatg
      481 aacccattga acaagtgtgg aaagagattc gtaaacgtgg atttaagaat aaagcctttc
      541 gaactttgga agatgtcatg aatcaactcc aagatgtcat acaaggactg gagaaggagg
      601 tgataaagtc catcgttaat cggagatgga atagaatgct ttttgaaagc agatgagtat
      661 aaaattgaat tgcttataaa aaagctccat acactggatg tgtatagagc aatggggctt
      721 tatttgatat agagttcttg gttttttagg acaatttctc ggatacttgc aaacttttta
      781 agttttttga tttcttctgg atgagtgacg agagtaataa catatccttc cttgcccata
      841 cggccagtac ggccagcacg gtgtgtgtag gtttcgctat ctctaggaat atcaaagttt
      901 acgacacatt ctaggctatc gatatcaatt ccacgagcca aaaggtcagt tgcaagaagc
      961 agggttagtt ggttatcttt aaacttttct aagatgattt ttctaaattt aacattaaca
     1021 tcactagcga gggaaacagc caatatatca cgatactgta gtttttcctc ggcattccca
     1081 aggtctgaca ggctattgaa gaagactaga ccacggaaat cctctacatg agccagtttt
     1141 cgcagcatat ccactcgatg acgttggtct acctgcatgt agaaatgctg gatattgtcc
     1201 aatttttgat cagagagatc aatagtgcgt gtattcggca caatcttttc ttggtcaaac
     1261 ttggtcgtgg cactcatgta gaccagttgg tggtcacgag gtgcgtagtg agtgattttt
     1321 tctacaaagt gaatctgaga atcatctagt aattggtcaa attcatccag gatgatggtt
     1381 tccacattca tcatcttgat ttttttaagt ttaatgagtt caaagatacg gccaggagtt
     1441 ccaatcagaa tttctggccc ctttttaaga cgttcaattt gtcgtttctg acttgaacct
     1501 gaaaggaaga gttgagcagt caatccgata gcttctgccc acgttttaca tacatcaaaa
     1561 atctgtccag caagttccgt atttggtgct agaatcaaga gttgttgggc ttttttcttt
     1621 tgtagtctga gaagacttgg taggagatac gctagggtct taccagttcc ggtttggctc
     1681 actcctagga ggttttctcc agcaagaagg ggctcaaata gttgagtttg aatgggggtg
     1741 aattcttgga aaccgagttg gtcactcagt tcttgccatt cagtcggtag tttggttttc
     1801 atttttctgc ctcaaatcta atgccagcag tctggcgcat ggtatatagt agctcatgaa
     1861 cagagcctgc atcatacagc caagtttggt agagattcag atctggttgc tggatcatgt
     1921 gtgcaaatgc agcgacttcc tcagtcatcg tatgaggagc ctgttggata ggaagctgga
     1981 cttgatttcc ttggtggtcg gtaaaaatag ctgagcgaat atgctcaatc gtgttgagag
     2041 tcaaggttcc atctgttgta taaatctcgc aaggaagatt ggaagtgatg ttttttccag
     2101 ccttgatgtg aacttgatag tctgggtaga agaggatacc atctccattt aggtcaatgc
     2161 tattgtcaag ctgttgagca tggtaagtcg cgtcattagc tttttcaaaa agacgaacag
     2221 cagcatagag gggataaatc cccaaatcca tgagggctcc accagcaaaa cggtctgaaa
     2281 agacatttgg tgtttgtcca gccaacaagt caggcatctt ggaagagtat ttggcatagt
     2341 tgaaatctgc tcctaacact tgcttatctg ctaaaaagtt tttgatagta gtaaaggctt
     2401 tctcgtggta attacgagct gcttcaaaga taaaacagtt atttttttca gctgtttgaa
     2461 tcaaatcaaa ccattcttgt ggttgagtga cagctggctt ttcgagaata acatgtttac
     2521 cagcagacaa ggcagctttt gcctgagcaa aatgtaagga gtttggactg gcgatataga
     2581 ctaaatcaaa agaagatttg aagaagactt ctaattgatc gaatagttgg atattctgat
     2641 agcgagaagc aaaggttgct gcagtttcta gttttctaga atagattgcg accagttggt
     2701 attctccact ggtatgggct gcttctatga aatgatggct gatagcgcca gttccgatga
     2761 cacctaattt tagcataaat actccttttc cgattttaaa tccttctttc attataacat
     2821 agatagacgg gactatccaa cagagaggag aaaatttcaa ataagctatt agctttcttt
     2881 tccgaataaa tagatagaag catagaatct agcaaaccta gatttaaaaa tgtgctataa
     2941 tagaaggagg aaaaggagga ttctcagaca tccaggtatc agcccaacta atgatttgtc
     3001 aatttatccg cgatatgctg gacttgccag caaaaaatgt gacgattttg gagggaagta
     3061 acattcacgt cttgccttcc atgccctact cagcgcaaga tttctatact agtatagacg
     3121 tcttggcgga gttagataat ggaatccaag ttatcatcga aattcaggtt catcatcaga
     3181 attttttcat caatcgccta tgggcttatc tgtgcagtca ggttaatcaa aacctagaaa
     3241 aaattcgcca acgtgaaggt gatacccacc agagctacaa acaaatcgca ccagtatacg
     3301 ctatcgcaat tgtcgatagt aattacttct cagatgacct agcttttcat agttttatag
     3361 taaaatgaaa tgagaacagg acaaatcgat caggacaatc aaatcgattt ctaacaatgt
     3421 tttagaagta taggtctact attctagctt caatctacta gaaattccat agatataaaa
     3481 ctacataatc tctacagata cggatgttgg agttgatgta agatgctttg gcttgctaga
     3541 ggaattgtgg attgccaaat tgtatcattg aaattattgc tcaaatttgt tatgatataa
     3601 atatgaataa aagtagacta ggacgtggca gacacgggaa aacgagacat gtattattgg
     3661 ctttgattgg tattttagca atttctattt gcctattagg cggatttatt gcttttaaga
     3721 tctaccagca aaaaagtttt gagcaaaaga ttgaatcgct caaaaaagag aaagatgatc
     3781 aattgagtga gggaaatcag aaggagcatt ttcgtcaggg gcaagccgaa gtgattgcct
     3841 attatcctct ccaaggggag aaagtgattt cctctgttag ggagttgata aatcaagatg
     3901 ttaaggacaa gctagaaagt aaggacaatc ttgttttcta ctatacagag caagaagagt
     3961 caggtttaaa gggagtcgtt aatcgtaatg tgaccaaaca aatctatgat ttagttgctt
     4021 ttaaggttga agagactgaa aagaccagtc taggaaaggt tcacttaaca gaagatggcc
     4081 aaccttttac acttgaccaa ctgttttcag atgctagtaa ggctaaggaa cagctgataa
     4141 aagagttgac ctccttcata gaggataaaa aaatagagca agaccagagt gagcagattg
     4201 taaaaaactt ctctgaccaa gacttgtctg catggaattt tgattacaag gatagtcaga
     4261 ttatccttta tccaagtcct gtggttgaaa atttagaaga gatagccttg ccagtatctg
     4321 ctttctttga tgttatccaa tcttcgtact tactcgaaaa agatgcggcc ttgtaccaat
     4381 cttactttga taagaaatat caaaaagttg tcgctctaac ctttgatgat ggtccaaatc
     4441 cagcaacgac cccgcaggta ttagagaccc tagctaaata tgatattaaa gcgactttct
     4501 ttgtgcttgg gaaaaatgtt tctgggaatg aggacttggt gaagaggata aaatctgaag
     4561 gtcatgttgt tggaaaccat agttggagcc atccgattct ctcgcaactc tctcttgatg
     4621 aagctaaaaa gcagattact gatactgagg atgtgctaac taaagtgctg ggttctagtt
     4681 ctaaactcat gcgtccacct tatggtgcta ttacagatga tattcgcaat agcttggatt
     4741 tgagctttat catgtgggat gtggatagtc tggactggaa gagtaaaaat gaagcatcta
     4801 ttttgacaga aattcagcat caagtagcta acggctctat cgttttgatg catgatattc
     4861 acagtccgac agtcaatgcc ttgccaaggg tcattgagta tttgaaaaat caaggttata
     4921 cctttgtgac cataccagag atgctcaata ctcgcctaaa agctcatgag ctgtactata
     4981 gtcgtgatga ataagcaaga aaaaataggt ctgttagata tttgacagac ttatttttta
     5041 cagaagatag tactacttaa aaaatgtttt atgctataat tgatgaataa aatagaagga
     5101 gaagcatatg aatacctatc aattaaataa tggagtagaa attccagtat tgggatttgg
     5161 aacttttaag gctaaggatg gagaagaagc ctatcgtgca gtgttagaag ccttgaaggc
     5221 tggttatcgt catattgata cggcggcgat ttatcagaat gaagaaagtg ttggtcaagc
     5281 aatcaaagat agcggagttc cacgtgaaga aatgttcgta actaccaagc tttggaatag
     5341 tcagcaaacc tatgagcaaa ctcgtcaagc tttggaaaaa tctatagaaa aactgggctt
     5401 ggattatttg gatttgtatt tgattcattg gccgaaccca aaaccgctca gagaaaatga
     5461 cgcatggaaa actcgcaatg cggaagtttg gagagcgatg gaagacctct atcaagaagg
     5521 gaaaatccgt gctatcggcg ttagcaattt tcttccccat catttggatg ccttgcttga
     5581 aactgcaact atcgttcctg cggtcaatca agttcgcttg gcgccaggtg tgtatcaaga
     5641 tcaagtcgta gcttactgtc gtgaaaaggg aattttattg gaagcttggg ggccttttgg
     5701 tcagggagaa ctatttgata gcaagcaagt gcaagaaatc gcagcaaatc acggaaaatc
     5761 gattgctcag atagccttgg cctggagctt ggcagaagga tttttaccac ttccaaaatc
     5821 tgtcacaacc tctcgtattc aagctaatct tgattgcttt ggaattgaac tgagtcatga
     5881 ggagagagaa aacttaaaaa cgattgctgt tcaatcgggt gctccacgag ttgatgatgt
     5941 ggatttctag aaaatcataa aaagaattgt acattattct aatttttgat ataatagtca
     6001 gcaggaaaga aagtcttatg gcgttcttca agcgagcttg ggatagtggg agccaagtag
     6061 ggcaaaataa tgagctggcg ctttctgtag tattttcaaa aacaatgaag taataaatta
     6121 gggtggaacc gcgtttctga cgcccctagg ttaaatcaac ctaggattgt cggacgcggt
     6181 tcttttgctt attcagtcta ttgtgtgaaa gaaaggagag ccgtggacaa cctttatctt
     6241 gtaaaagacg atagtcaact agctacattt cgtgattttg tagtaagaaa tactgaaaag
     6301 ttgaaagatt atcaatcttt tttaaagaat gaacttgcag tctgtgattt accgcaagcc
     6361 gttatttggt cagattttaa tgctgctaca cagattatta gggaaagcgc tgttccagcc
     6421 tatacaaata atagacgaat ggttatggcg cctgatttag ctgtttggaa agagttgtat
     6481 ttgtatcaat tgatggacta cgagtgttct cagcaaactc aagcaataga aagtcactat
     6541 cattctttat ctgaaaattt cctcttacag attgtaggac atgagttagc tcattggtcg
     6601 gagcattttt tagatgattt tgatggttat gactcttata tctggttcga agaggggatg
     6661 gttgaatata ttagtcgcaa gtatttcttg acagaagagg aatttcaagc ggaaaaaatt
     6721 tgtaatcaat ctctcgtaga actttttcag aagaagtatg gttggcattc attgaatgat
     6781 tttggttctt cgacttatga taagaactat gcaagtattt tttatgaata ctggcgcagc
     6841 tttttgacag tagataagtt ggtagaaaat ttaggtagtg tacaagcggt cttagattct
     6901 tatcatttat gggcaaatac agaaaaaact tttcccttgt tagattggtt tgttcagcag
     6961 aaattaattg aaaaagaaat ataaaaacta aaggagtaaa caatgtctaa gaaattgaca
     7021 tttcactgcg tcagtggcag aaacctcctt acagtcggac tgccccacgc tcagcactag
     7081 agtgcctgag ctagacgcag tactaactcg tcttgcctcg tatgatcgac gaggcagact
     7141 catgtcgcaa gtaatttata taaaaaggag taaacaatgt ctaagaaatt gactttccag
     7201 gaaatcatcc ttactttgca acaattttgg aatgaccaag gttgtatgct tatgcaggct
     7261 tatgataatg aaaaaggtgc gggaacaatg agtccttaca ctttccttcg tgctatcgga
     7321 cctgagccat ggaatgcagc ttatgtagag ccatcacgtc gtcctgctga cggtcgttat
     7381 ggggaaaacc ctaaccgtct ctaccaacac caccaattcc aggtggtcat gaagccttct
     7441 ccatcaaata tccaagaact ttaccttgaa tctttggaaa aattgggaat caatcctttg
     7501 gagcacgata ttcgttttgt tgaggacaac tgggaaaacc catcaactgg ttcagctggt
     7561 cttggttggg aagtttggct tgacggaatg gaaatcactc agttcactta tttccaacaa
     7621 gtcggtggat tggcaactgg ccctgtgact gcggaagtta cctatggttt ggagcgcttg
     7681 gcttcttaca ttcaagaagt agactctgtc tatgatatcg agtgggctga tggtgtaaaa
     7741 tacggagaaa tctttatcca gcctgagtat gagcactcaa aatattcatt tgaaatttcg
     7801 gaccaagaaa tgttgcttga aaactttgat aagtttgaaa aagaagctgg tcgtgcatta
     7861 gaagaaggct tggtacaccc tgcctatgac tatgttctca aatgttcaca tacctttaat
     7921 ctgcttgacg cgcgtggtgc cgtatctgta acagagcgtg caggctatat cgctcgtatc
     7981 cgtaacttgg cccgtgtcgt agccaaaacc tttgtcgcag aacgcaaacg cctaggctac
     8041 ccacttttgg atgaagaaac aagagctaaa ctcctagcag aagacgcaga ataaagagag
     8101 tgacaaatta cgaaaatggg cgaacagagt gagccctgag ccagttgccg cagtgatgaa
     8161 ggtatcctta gtgaaactaa ggatactagg caaaattgga gacttttggc tccaatttta
     8221 gcaatgaaac aacgaagttg gttgcttgcg tgccaatcac ataaggcaaa ctggaaaata
     8281 aaaagatact tttcggagaa aaaacatgac aaaaaactta ttagtagaac tcggtcttga
     8341 agaattacca gcctatgttg tcacaccaag tgaaaaacaa ctaggcgaaa aaatggcagc
     8401 cttcctcaag gaaaaccgcc tgtcttttga agccattcaa accttctcaa caccacgtcg
     8461 tttggctgtt cgtgtgactg gtttatcaga caaacagtct gatttgacag aagatttcaa
     8521 gggaccagca aagaaaattg ccttggatag tgatggaaac ttcaccaaag cagctcaagg
     8581 atttgtccgt gggaaaggtt tgactgttga agatatcgaa ttccgtgaaa ttaagggtga
     8641 agaatatgtc tatgtcacta aggaagaagt tggccaatca gttgaagcca ttgttcctgg
     8701 tgttgtagat gtcttgaagt cattgacttt ccctgtcagc atgcactggg ctggaaatag
     8761 ctttgaatac atccgccctg ttcacacttt aactgttctc ttggatgagc aagagtttga
     8821 cttggatttc cttgatatca agggaagtcg tgtgagccgt ggccatcgtt tcttggggaa
     8881 agaaaccaaa attcagtcag cattgagcta tgaagaagac cttcgtaagc agtttgtaat
     8941 cgcagatcca tgtgaacgtg agcaaatgat tgttgaccaa atcaaggaaa ttgaggcaaa
     9001 acatggtgta cgtatcgaaa ttgatgcgga tttgctgaat gaagtcttga atttggttga
     9061 atacccaact gccttcatgg gaagttttga tgctaaatac cttgaagttc cagaagaagt
     9121 cttggtgact tctatgaagg aacaccagcg ttactttgtt gttcgtgatc aagatggaaa
     9181 actcttgcca aacttcattt ctgttcgtaa cggaaacgca gagcgtttga aaaatgtcat
     9241 caaaggaaat gaaaaagtct tagtagcccg cttggaagac ggagaattct tctggcgtga
     9301 agaccaaaaa ttggtgattt cagatcttgt tgaaaaatta aacaatgtca ccttccatga
     9361 gaagattggt tcccttcgtg aacacatgat tcgtacgggt caaatcactg tacttttggc
     9421 agaaaaagct ggtttgtcag tggatgaaac agttgacctt gctcgtgcag cagccattta
     9481 caagtttgac ttgttgacag gtatggttgg tgaatttgac gaactccaag gaattatggg
     9541 tgaaaaatac acccttcttg ctggtgaaac tccagcggtg gcagctgcta ttcgtgaaca
     9601 ctacatgcct acatcagctg aaggagaact tccagagagc aaggtcggcg cagttctagc
     9661 cattgcagac aaattggata cgattttgag tttcttctca gtaggattga ttccatcagg
     9721 ttctaatgac ccttatgccc ttcgtcgtgc aactcaaggt gtggttcgta tcttggatgc
     9781 ctttggttgg cacattgcta tggatgagct gattgatagc ctttatgcat tgaaatttga
     9841 cagtttgact tatgaaaata aagcagaggt tatggacttt atcaaggctc gtgttgataa
     9901 gatgatgggc tctactccaa aagatatcaa ggaagcagtt cttgcaggtt caaactttgt
     9961 tgtggcagat atgttggaag cagcaagtgc tctcgtagaa gtaagcaagg aagaagattt
    10021 taaaccatct gttgaatcac tttctcgtgc ctttaacctg gctgagaagg cagaaggggt
    10081 tgctacagtt gattcagcac tatttgagaa tgaccaagaa aaagctttgg cagaagcagt
    10141 agaaacactc gttttatcag gacctgcaag tcagcaattg aaacaactct ttgcgcttag
    10201 cccagtcatt gatgctttct ttgaaaatac tatggtaatg gctgaagatc aggctgtccg
    10261 tcaaaatcgt ttggcaatct tgtcacaact aaccaagaaa gcagctaagt ttgcttgttt
    10321 taaccaaatt aacactaaat aaaatttgat aaacggactt tatcttatta caaaggagaa
    10381 gaaatggatc cgaaaaaaat tgctcgtatc aatgagcttg ctaaaaagaa aaaaacagaa
    10441 ggcttaacac cagaagaaaa agtggaacaa gccaaactac gtgaggagta catcgaaggt
    10501 tatcgccgcg ctgttcgtca ccacattgaa ggaatcaaaa ttgtggacga agaaggaaac
    10561 gatgttacac cagaaaaact acgccaagta caacgtgaaa aaggattaca tggccgtagt
    10621 cttgatgatc caaattcata ataatactct tcgaaaatca aattcaaacc acgtcagctt
    10681 caccttgccg tacttaagta cagcctgcgg ctagcttcct agtttgctct ttgattttca
    10741 ttgagtatat gtattctttc ttttaacaaa gatagatgaa acgataacaa agagactagc
    10801 agtttgtgtt tgctagtctt ttttcgctaa aaaaggaacc ataatggttc ctaaaaacta
    10861 tcattagtaa cttgcaccgg ctgtagcgtc tgcgtcacca ccgtggcctc cagcatcccc
    10921 tgaatcagaa gcgccagaag tagcatcggc gtctccatga cctccggcag caggagcaaa
    10981 tggtccgcta ccacccacca aacgttgacc agtctctttt aggtaccagt caagccatgg
    11041 ttggaagtta aagacgattt cattgatacc agcgtatgat ccatcaggat agtacattgc
    11101 ttggtagttg tgagtgttga taacacctgc aggagaacct ggaacgatcg tacggacgta
    11161 ttcttggttt acgttgcgaa gtgttccgat aacccactct acgttcttca tacgtgctgg
    11221 tggaagagaa ccatgaacag tcgacatacg gctacctgat tgaggtggta cacgtttagc
    11281 gaacatagtg tctggatctt ggtgagcgtt gttgtagtag aggaattggt tgttgtcgtc
    11341 agcgtatgtc aattcaaatg gcatagcttt caagaacata tcaatttggt taactgttag
    11401 gataccgtgg tccaatttga cataggtatc accagaaaca gcaccagtga atgctgcaac
    11461 tttttctacc cattctggat cgtcagggtc aacttctgtg atggttgtag cgattggttt
    11521 tccacaatcc aagtcttctg attcgattgg ttttggtttt ttcaatttcg aaacgactcc
    11581 tacgtattta acaaagttat ctaagcaagt ttcaaggaat ttaacagtgc cttcgttggt
    11641 gatatttccg ttgttatcaa aagcttcctt agctttacca agaaggaatt cgttacctgg
    11701 aagcgtgtag gcattaacac ctggagcatc aaggatttta cgaaggtgaa cttgagcacg
    11761 tgatgttcct tggtcatagt atgatgcacc cacaatcata acaggcttgt tttcaaatgg
    11821 atgaacttcg tatgaaagcc attcaagtac agatttgagt gaagctgaga tagtgtggtt
    11881 atgctcagga gtagcaatga taacaccatc tgcacgagta attttgttat ataaataacg
    11941 taattggaaa ctttcatccc atttttcatc ttggttaaac attggaactt cgtcaatttc
    12001 aagaacttct aattcaaatt tgagtttgaa gtagcgacgg ataaattcca agagcttacg
    12061 gttatatgat tgatcgtagt ttgatccaac aagtccaaca aatttcattc tttttggtct
    12121 cctatcttac aaattttccc agtcaaagtc ttcagcatct ttgcgaagta attcttgtgc
    12181 attacgtaat ttttctgtga tttttacaaa gatacggaag tcatcaaaga tggcatccaa
    12241 tttcttgata acatcaaggt caaccaagtc gccacttggg ttaaatgctt gaagagagtg
    12301 tgagagcaag aattcatctg gaagaacatt tgccttgatt tcaggagcat tcaagatttg
    12361 acgaagttgc aattgggcac gagatgaacc aagcgtaccg taagaagcac ctgtaatcat
    12421 gattggtttg ttcaaaagtg ggtaaatacc ataagataac caagcaagag cgctcatcaa
    12481 aacagctgga atagagtgat catactcagg agtaccgata ataacgccat ctgcctcttc
    12541 gattttagca gcaatttcca atatttcagc aggtacttgc ttgtcagctg gtttgttgaa
    12601 gacaggaatg gccttgattt caacaagttc aatttcagct ttgtcagtaa agtgtttttg
    12661 catgtattga agcaattgac ggtttgtaga acgttttgaa tttgttccaa caatagcaat
    12721 aagttttaac atgagatttc ctttctcttt ttacataata caattttaaa attccattga
    12781 aacagttgtc tctatagagt aggaattcct gaagaacagc ttaggtggcc ttctttatcg
    12841 atgaggatga cttcgatgcc ctccaaactt tcgacttgcc agaggataga agcaggtctt
    12901 tctccaaaga gtcgagtcgt ccagatttcg ccatcgactg atttatcaga gatgattgtt
    12961 agactcgcta gttccgtttc aacaggatat cctgtttgac tgtcaaaaat gtgatggtaa
    13021 tcttgtccat cgacggtcag gtgacgttca taaatgcctg aagtcacgac agatttattg
    13081 acaacaggga tggtcattaa atgatttccc ctaggattgg ctgggtcttg aatcccgatt
    13141 tgccatgggt tatcccctct tgcctgattt tttccaatgg tcaggatatt ccctcccaga
    13201 ttgatcaagg cagaagtcac cccctctttc ctaagaaatt gggcaacctt atccgcactg
    13261 tatcctttgg ctaaacaacc tagatcgatc ttcattcctt tctgttttaa aaacacagta
    13321 gaagtagaag aatctaactc gataccatga ggattgatta gaggcagcac cgattcaatt
    13381 tcttgaggct gggcgacctt ggcatctgaa aaaccgatac gccaggtttg aattaaggga
    13441 ccaatgctga tattgaggtg gctagagagc gctaggctat gctctaaccc aagtgaaatc
    13501 agctcaaaca ggtctggatg aaccgtgacg ggggctattc ctgcttgata attgatttcc
    13561 atcaactcag attcttgact attggcgttg aagcggtatt caagttcttt gagcaagtca
    13621 aaggattttt ggagaaagat atcggcttgc tcatccacta atgaaatagt gatagtagtc
    13681 cccattagcc gttcagaatg tgaacgaaga gtcaagctac caactccttt ctcttataga
    13741 aaataagttg taatatcaaa taatcatcta aattgaagcc cttacatttc attttcatgt
    13801 tattataata ccataaagtt agaattttca caaacaaaat ttggaaaaag tcaagaaata
    13861 tgctcataaa attcatcagg cttgaaaaca ggataaatgg ggaattattt ttgataaaaa
    13921 atgctgaaat aatagtaccc cccttgtaaa cgctaacggt aaatggtata ctagtaaggt
    13981 aaatttagaa tgaaggcagg aaatttttat gagtaaaatc gttgtagtcg gtgctaacca
    14041 cgctggtaca gcatgtatca ataccatgtt ggataatttt ggaaatgaga acgaaattgt
    14101 tgtatttgac caaaactcta acatctcttt cctaggatgt ggaatggctc tttggattgg
    14161 tgaacaaatt gacggtgctg aaggcttgtt ctattctgat aaagaaaaat tggaagctaa
    14221 aggtgctaaa gtttacatga actcacctgt tctttcaatc gactatgata acaaagtagt
    14281 tacagcggaa gttgaaggaa aagagcacaa agaatcatac gaaaaattga ttttcgctac
    14341 aggttctaca ccaatcttgc caccaatcga aggtgttgaa attgttaaag gaaaccgcga
    14401 atttaaagca actcttgaaa acgtacaatt cgtgaaattg taccaaaatg ctgaagaagt
    14461 tatcaataaa ctttctgaca agagccaaca cctcgaccgt atcgccgttg ttggtggtgg
    14521 ttacatcggt gttgaacttg ctgaagcctt tgaacgtctt ggaaaagaag ttgtccttgt
    14581 tgatatcgtt gatactgtct tgaacggtta ctatgacaaa gacttcacac aaatgatggc
    14641 gaagaacttg gaagatcaca acatccgctt ggctctaggt caaactgtta aagcaatcga
    14701 aggtgacggt aaagttgaac gcttgattac tgacaaagaa agctttgacg tggatatggt
    14761 tatccttgca gttggtttcc gtccaaacac agcccttgca ggtggtaaga tcgaactctt
    14821 ccgcaacggt gccttccttg tagacaagaa acaagaaaca tctatcccag acgtttacgc
    14881 tgttggtgac tgtgcgactg tttatgacaa tgctcgtaaa gatacaagct atatcgctct
    14941 tgcttcaaat gctgttcgca ctggtatcgt tggtgcctac aatgcttgtg gacatgaatt
    15001 ggaaggaatc ggtgttcaag gttcaaatgg tatctcaatc tacggtcttc acatggtttc
    15061 aactggtttg actcttgaaa aagcgaaagc tgctggttac aacgcaactg aaacaggctt
    15121 taacgatctt caaaaaccag aattcatgaa acatgacaac catgaagtag caattaagat
    15181 tgtctttgac aaagatagcc gtgaaattct tggtgcccaa atggtttccc atgatattgc
    15241 aattagcatg ggaatccaca tgttctcact tgctatccaa gagcatgtga caattgataa
    15301 attggcattg acagacctct tcttcttgcc acacttcaac aaaccataca actacatcac
    15361 aatggctgcc cttacggctg aaaaataaaa at
//
LOCUS       DAYYYC010000050        14466 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.050, whole genome shotgun sequence.
ACCESSION   DAYYYC010000050 DAYYYC010000000
VERSION     DAYYYC010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.050"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(177..992)
                     /locus_tag="ACHBV5_001683"
     CDS             complement(177..992)
                     /locus_tag="ACHBV5_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFM9967444.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(989..1894)
                     /locus_tag="ACHBV5_001684"
     CDS             complement(989..1894)
                     /locus_tag="ACHBV5_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFM9967445.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(1895..2026)
                     /locus_tag="ACHBV5_001685"
     CDS             complement(1895..2026)
                     /locus_tag="ACHBV5_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFM9967446.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKVKAEKKN"
     gene            2284..2595
                     /locus_tag="ACHBV5_001686"
     CDS             2284..2595
                     /locus_tag="ACHBV5_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFM9967447.1"
                     /translation="MERQTLKDIEVIIVNQSTEEIASISQQMNLSFNIKIIDENSFAE
                     LSDMITGDYITFLSSNDSLFDWTFEKMYHAIKLSDSDVVLGHFADLVDGVFYFYPLGG
                     G"
     gene            2600..3604
                     /locus_tag="ACHBV5_001687"
     CDS             2600..3604
                     /locus_tag="ACHBV5_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HFM9967448.1"
                     /translation="MTENLTNVQVLQKMDDTDHRIRKQYRSLFGKLFNSKLLRKINQF
                     DINNLIWRLYIHSKTATYINFPTYIYKPVIDAKPLKDSYKIILENYENRIKDCAVLEN
                     YDIERAKKQYIQELANFSAWLKNDGEYLDSDIVYHKLIAAEKGIFPFLELDRLDFTII
                     SNNCVGGLIYKQLGFQYRTPFVGLFILPDDYYKLTKHFRYYMEQELVFEEELISPSWT
                     HEVYPLGHLGDIDIHFLHYSSIEEARTKWEKRKKRINWNNLYFKFDNKDSASEEILNK
                     MDNLPYSNKLILVNRPYKNLKSQCVIPGQEHLPELAIMSDPLNTFDIMAWLKKGGNAL
                     "
     gene            3706..5835
                     /locus_tag="ACHBV5_001688"
     CDS             3706..5835
                     /locus_tag="ACHBV5_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFM9967449.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            5822..6271
                     /locus_tag="ACHBV5_001689"
     CDS             5822..6271
                     /locus_tag="ACHBV5_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFM9967450.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            6329..6601
                     /locus_tag="ACHBV5_001690"
     CDS             6329..6601
                     /locus_tag="ACHBV5_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFM9967451.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(6955..7146)
                     /locus_tag="ACHBV5_001691"
     CDS             complement(6955..7146)
                     /locus_tag="ACHBV5_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967452.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            7574..8332
                     /locus_tag="ACHBV5_001692"
     CDS             7574..8332
                     /locus_tag="ACHBV5_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9967453.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            8334..10322
                     /locus_tag="ACHBV5_001693"
     CDS             8334..10322
                     /locus_tag="ACHBV5_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9967454.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(10364..11038)
                     /locus_tag="ACHBV5_001694"
     CDS             complement(10364..11038)
                     /locus_tag="ACHBV5_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HFM9967455.1"
                     /translation="MDSNFAGRLNILRAGVLDANDGIISIAGVVIGVASATSNIWIIF
                     LSGFAAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYASYIQN
                     GEFKTSAQLLTNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPML
                     SVTIFPSDYRIPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLL
                     EQLFSI"
     gene            complement(11034..12029)
                     /locus_tag="ACHBV5_001695"
     CDS             complement(11034..12029)
                     /locus_tag="ACHBV5_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFM9967456.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVRKSSVTKELKEKILHYHNQ
                     KFSPEMMVMVKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKSAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGIKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRN"
     gene            12736..14211
                     /locus_tag="ACHBV5_001696"
     CDS             12736..14211
                     /locus_tag="ACHBV5_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFM9967457.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(14177..>14466)
                     /locus_tag="ACHBV5_001697"
     CDS             complement(14177..>14466)
                     /locus_tag="ACHBV5_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFM9967458.1"
                     /translation="SDWKVQYTRCLDIIFPELDKIVGKHSEYTYQLLTRYPNPQKRIE
                     AGFDKLIEIKRLTASNSRAFCRALKSSPNHQIEIRNSLDKTIDFSYSLSFS"
BASE COUNT         4426 a         2659 c         2989 g         4392 t
ORIGIN      
        1 ctgaatatca aaaaagaaag aacgaaattt gtcctttctc gagcttagct gacttcaacc
       61 cactacagtt gacaaagagc caatctacaa gtcactaatt ttcatataac aaaaaaacga
      121 acaggctctt tttctgttat tcagaagaga acttgttcgt ttttatcttg attttcttaa
      181 aaagctctat atacataggg attttctggt ttatcgactt tggtaaagct gtcgatttcc
      241 aaggttggaa ggttttgttt gagttcttta tggtagtgat tgaccagttt tcctttggct
      301 gtaatccagg tgttgttttc atactgccgg gtattgccct tggtcagcaa tccatagaca
      361 ccagaatctg cgatacagtg gataatgccg aatcggaaca gaaattgact attggcatga
      421 ctggggtcgt tatagacaaa gcctgtaaac tggattgtct tgccctcaaa ttcatctgga
      481 tagtcgtaga tagcctccat gacttccata tagttttcat tagtgatctg aatactatct
      541 tgggataagt atttatccgc cgccgttcgc atttcctttt cataggctga ttttgaaaaa
      601 taagaactag tatctggttt caaatattgg cttgtcgtcc cttcacttgt ctgaatagct
      661 agatccgttc cttccgatag ggggaaatga taacctttag cagaaacggt ctgagaatcc
      721 aagctaacag ttgggaaagt taagccgatg acaagtggaa tagccagaag agaaatactc
      781 gtcatcttgg ccaatcggct gttcagatga ctgtgggttt tgacttgctt catccagata
      841 tacaattgaa caattgccaa gataaaggaa agcaccatgg agatataggc cagataggaa
      901 tagtgcatgt tgatgtactg gtttagtttg cccgacagat ggaggtaaat agtcagttca
      961 aaatagccag ctaaaactaa aaatcgaatc ataggatgac tccaatcaag agagaatagg
     1021 ctaaaacgac cagagtcaca atcgtaatga agtgactaat aaatcgtgct ttcaagtaat
     1081 ttttcatcat gagaatattt ttgatatcca gcattgggcc aatgacgaga aaggccagaa
     1141 ctggtgccaa accgaaactc gagagtagag aagcacctat aaaggcatcc gcctcactac
     1201 agagcgaaag aagaaaggct aaaagcatca agagcaggat agcaaaaaga ggagtcgcac
     1261 tgatagaggt cagaatccga gtcggaacgt agacctgtat tatagaagca aagaggcagc
     1321 caaataccaa ataacgcccc gtatcaaaaa attcatcaat ggcctgcaca aagacttgaa
     1381 aaactttttt tgcagaactc aagtaagaaa aatcatgctc atgacaagcc agacgatttt
     1441 ctttctgaat cggttcttgc cagaaaaatc ctagaaaaat tcctagtatt acagccacaa
     1501 gaatggaacc cagagctcgt aatagggcga catggaagga gttgccaaag gcagaatagg
     1561 tcgcaaaaag aacaatggga ttgataacag gtgctgtcac aagaaaagga acggccgtgt
     1621 aacttggaac ctttttttcc agaaaacgat tgatgatggg gacgattcca cattcacaag
     1681 aagggaaaag tataccgaca aaggtcccaa aaaagattct cccccaacga tttcgaggga
     1741 gaaaatgata aaccttgtca ggtgtgatat aaacttcaat cagccctgag acaatgcttc
     1801 ctatcagaac gaagggaagg gcttcaatga taatggagag aaaaatggct ccagtttgaa
     1861 gtacactaga tgggagttgt tgaaaagcag tcatctagtt tttcttttct gctttgactt
     1921 ttttctcttt gtcatcaggg aaagtaactt gtttcaaatc agggagttta gcaaactctt
     1981 caaacatctt gtccaagtcg tctcgttttg taaatttgac agccataggt gtacctcgat
     2041 tctaaattct acctctatta tactattatt ttgcggaaaa gggaaaagtt aaaatttcaa
     2101 attgagtagc taagagataa tatagcttga tattacctga tatatatcat aattgtgcta
     2161 taattaaata aaaagaaaat cattatcaga aaattatggg aggtagtcaa actgacttac
     2221 tcaattagtg ttgttttgtt acatcaagga gataaaaata gtttattaga gtctttgtca
     2281 atagtggaga gacaaacatt aaaagatata gaagttatta ttgtaaatca atctacagag
     2341 gagatagctt ccattagcca acagatgaat ctatcattta atattaagat tatagatgag
     2401 aattcttttg ctgagttgtc tgatatgatt acaggagatt atattacgtt tctatcttca
     2461 aatgattcat tatttgattg gacatttgaa aagatgtatc atgcgataaa attatccgat
     2521 tctgatgttg ttcttggtca ttttgctgat ttggttgatg gagtatttta cttttatcct
     2581 ttgggggggg gataattggt tgacagaaaa tttaacgaat gttcaagttt tacaaaagat
     2641 ggatgataca gatcatcgaa ttagaaaaca atatcgctca ttatttggaa aattattcaa
     2701 tagtaagctt ttacgaaaaa taaatcaatt tgatataaac aaccttattt ggagacttta
     2761 tattcactct aaaactgcaa cctatattaa tttcccgaca tatatctata aacctgttat
     2821 agatgctaaa cctctaaaag actcctacaa aatcatatta gaaaattatg aaaatagaat
     2881 caaagattgc gccgtcttag aaaactatga tatagaaaga gcgaaaaaac aatatattca
     2941 agaattggca aattttagtg cttggttaaa aaatgacggt gaatatttag attctgatat
     3001 tgtttatcat aagttaatag ctgcagagaa aggaattttc ccttttcttg agcttgatag
     3061 attagatttt acgattataa gtaataattg tgttggagga ttaatttata aacagcttgg
     3121 ttttcaatat agaacacctt ttgttggttt atttattctt cctgatgatt attataaact
     3181 tacaaagcat tttcgttatt atatggaaca agaacttgtt ttcgaagagg aacttatttc
     3241 accgagctgg actcatgaag tttatccttt ggggcactta ggagatatag atattcattt
     3301 tctacattat tctagtattg aagaagcacg aactaagtgg gaaaaaagaa aaaaacgcat
     3361 aaattggaat aatctttatt ttaaatttga taataaagat tcagctagtg aagaaatttt
     3421 aaataagatg gataatcttc cttattctaa taaattaatt ttagtcaatc gtccatataa
     3481 aaatttgaaa agtcaatgtg ttattccagg tcaggaacat cttccagaac tggctattat
     3541 gtctgatcca ttaaatactt ttgatatcat ggcttggtta aaaaaaggtg gcaatgctct
     3601 ttaagtgcaa gttattgcgc tgtagcatat aaatctattt cctacatatt ttttaaatgt
     3661 tctacgagtt aatttgaaac gtttagcttg tggtataata gatttatgga taaaaaatat
     3721 gaaaaaatct ctcaggattt gggagtgacg ttaaagcaaa ttgataccgt tctaagtttg
     3781 acagctgaag gggcgactat tccctttatc gcgcgttatc gcaaggacat gactggtagt
     3841 ctggatgagg tggcgattaa ggctattatt gatttggata aaagtctgac aaatctcaat
     3901 gaccgtaagg aagctgtctt agctaagatt caagaacaag gtaagttgac caaggaattg
     3961 gaagaagcta tcttagttgc cgaaaaatta gcagacgttg aagaactcta tcttccttat
     4021 aaggaaaagc gtcgtaccaa ggcaaccatt gcccgtgaag ctggactctt tcctcttgct
     4081 cgtttgattt tgcagaatat agttgactta gagaaagaag ctgaaaagtt cgtctgtgaa
     4141 ggatttgcga ctggcaagga agccttgacc ggtgcagttg atattttggt cgaagcctta
     4201 tcggaagatg tgaccttgcg ttctatgact tatcaggaag tgctgagaca ctctaaactc
     4261 acttctcaag ccaaggatga aagtcttgat gaaaagcagg tttttcagat ttattatgat
     4321 ttttcagaga cagttggaac tatgcaaggc tatcgtacct tggctctcaa tcgtggggag
     4381 aaacttggtg tcttgaagat cggttttgaa catgcgacgg accgtattct tgccttcttt
     4441 gctactcgtt tcaaggtgaa aaatgcttat attgatgaag ttgttcagca atccgttaag
     4501 aaaaaggtct tgcctgctat tgagcgtcgt attcggacag aattaactga gaaagctgaa
     4561 gagggagcta tccaactttt ttctgacaat ctgcgcaatc tcctcttggt tgctccactg
     4621 aaagggcgcg tggttcttgg gtttgaccca gcctttcgta caggtgccaa gctagctgtc
     4681 gtggatgcaa caggaaaaat gctgacaact caggttattt atcctgttaa accagcatca
     4741 gctcgtcaaa tcgaagaagc caagaaagat ttagcagatt taattggtca atacggtgta
     4801 gagattattg ccattggaaa tggaacggcc agtcgtgaaa gtgaagcttt tgtagcggaa
     4861 gttctgaaag atttccctga agtcagctat gttatcgtta atgaaagtgg tgcttctgtc
     4921 tattctgcca gcgaacttgc tcgtcaggag tttccagact tgaccgttga aaaacgctct
     4981 gccatttcta tcgcccgtcg tttgcaagat cctcttgcgg aattggtcaa aatcgatcct
     5041 aagtcaattg gtgtcggtca ataccaacac gatgtcagtc agaagaaact atctgagagt
     5101 ctggactttg ttgtcgatac agtggttaac caagttggtg tcaatgtcaa tacagctagc
     5161 ccagctcttc tttcacacgt agctggactc aataaaacca tttctgaaaa tatcgtcaaa
     5221 taccgtgagg aagagggaaa aatcacttca cgctcccaaa tcaagaaagt tcctcgtttg
     5281 ggggccaagg cttttgaaca ggctgctggt ttcctccgta tccctgaaag tagcaatatc
     5341 cttgataata caggagttca cccagaaaat tacgctgccg ttaaggaact cttcaaatgc
     5401 ttggacatta aggatctgaa tgaagaggcc caaagtaaac tcaagtcgct ttcagtcaag
     5461 gaaatggcgc aagagttaga ccttggtcca gaaactctta aagatatcat tgcagatctt
     5521 ctcaaaccag gtcgagattt ccgtgattcc tttgatgctc cagttctccg tcaagatgtc
     5581 ctagatatca aggacttagt ggttggacaa aagctagaag gagtggtgcg taatgttgtt
     5641 gatttcggtg cttttgttga tatcggaatt catgaggacg gtctcatcca tatttcccat
     5701 atgagtcgca agtttatcaa acaccctagt caagtggtgg cagttggaga tttggtgagc
     5761 gtttgggtta agaaaattga tactgaacgt gaaaaagtta atctgtctct cctagctcca
     5821 aatgaaactg actgattacg tcaagcaggt ttcactagaa gacttcggca gaccttttat
     5881 ccatcatgtc cagtggaata ggcgtctacg ttcgacaggt gggcgatttt tccccaaaga
     5941 tgggcatttg gattttaatc ccaaggttta tcaggaactg gggttggacg tttttaggaa
     6001 aattgtccga catgaactct gtcattatca cctctatttt caagggaaag gctatcaaca
     6061 caaggatcgg gattttaagg aactgttgaa agcagtggat ggattacggt ttgtaccatc
     6121 cttgcccaat agtaactcca agccaatcaa gctctatcgt tgccaatcct gccagcaaac
     6181 ttatcagcgt aagcgtagga ttgataccca acgctatcgc tgtggacttt gtcgaggaaa
     6241 gttgctatta gtaaatcagc ctgaggactg atgaaagccg agcctatccg tgatatacta
     6301 gtctaaccta gcagaaagag gaaatatcat gaacagtaag ttttataaaa tgagacgaaa
     6361 tcgcatgatt tcaggagttt tagcaggtct gtcagacaag tggaactttg atgttaccct
     6421 tgtacgtttt ctgtttgcca tttttacagt cgcaaacttt ggacttgggg tgattatcta
     6481 tatcatccta gcttctatca tgccaaccaa ggaagaaatc gaagcagaaa tgtacggaac
     6541 aggcccacgt aaacgcaaag aagctcaagc cattgacgat aatgaaggct ggttttggtg
     6601 aggttttaca aaagatttgg aatacgcaaa aagctttaaa tcaatagtct aaactgcttg
     6661 atttaaagct tttttacttt tatactcaat aaaaatcaaa gtgcaaacta ggaagccagc
     6721 cgcaggctgt aatttagtcg gcaatgtgaa gttgatatag tttgcacttt gatttttgaa
     6781 tagtattaat aatatttcgc cagcttcatc cacaaactat agtggattgg aactagaata
     6841 ggacacctat acttctaaaa aattgttaga aatcgatttg actgtcctga tcgatttgtc
     6901 ctgttcttat ttcattttac tataaaagca gtaatttaaa cgcagttttt taatctattt
     6961 ttgctgttga gacaatacat ttttggaaaa atggtggatg ctgataacaa ctgataacca
     7021 gcaaataaca taagcagtgc cggtaaattc tgtaccgata aagtgtgtgt gttcaactaa
     7081 gagctgaccg atgaatggag agagcagata gagaagtccg atgagtatat gttctttgtg
     7141 tttcattaaa gcgcaccttc tttccttata ggttgaacga cttgcaagtg ttaaattgaa
     7201 tggtatgtta tctaggtaac cttactaaaa tgttagttcc cgcttcctcc ttttcaaagt
     7261 aagccttttc acacttatat tttacaactt taaaaatagg aaatcaaatc attttctaag
     7321 taattttgct tatatttcac ccaatcttac aaaaatgtaa gattaaagtc tcttttgtaa
     7381 ggttaggtta tggcaagcgg tctttttttg atgtaaacta gactcataaa gaacaaagga
     7441 gtaacatcat gaaacaaatc ttacataaga aaactagaaa accaagtcac aaagaaattg
     7501 agcgcgttca gctgggatgc actatgatgc aagctacatt tcatttgatg ggatattaag
     7561 aaaggagatt ctcatgacac ttttagatgt aaaacacgtt caaaaaattt ataaaacacg
     7621 ttttcagggc aaccaagtag aagccctcaa ggatattcac tttaccgtcg aaaagggtga
     7681 ctacgttgcc atcatgggtg agtctggttc tggtaaatca actcttctca atattctagc
     7741 tatgctggat aaaccaagtc gtggtcaggt ttacttgaat ggaactgaca ccgcaaccat
     7801 taaaaattca caggcctcta gcttccgtcg tgaaaagttg ggctttgtct tccaagactt
     7861 taacttgcta gatactctat ctgtaaagga caatatcttg cttccgcttg tcttgtcaag
     7921 aagacctatt acagagatga tgaagaaatt ggtggtgaca gctgagaatc tgggaataaa
     7981 ccaattacaa gagaagtacc cttacgagat ttctggtggt cagaaacagc gtgtagcagt
     8041 agcccgcgcc atcatcacag aacctgaaat tctccttgcg gacgaaccga caggagctct
     8101 tgactccaag tcatctgcag ccttacttga tgtctttgat gaaatcaatg agcgcggcca
     8161 aaccattctc atggtaaccc actcaacagc agcagctagc agagctaaac gtgtactctt
     8221 tatcaaagac ggcattcttt acaatcaaat ctaccgtgga gagaagacag aacgtcagat
     8281 gttccaagaa atctctgata ccttgactgt catggcaagc gaggtgaatt agtatgtttc
     8341 gattaaccaa taagttagcg gtatcgaact tgattaaaaa ccgcaaactc tactatcctt
     8401 ttgcgctggc tgttctcttg gcagtcactg tcacctatct cttttactct ctaaccttca
     8461 atcctaagat tgcggaaatc cgtggaggaa caaccattca ggctacactt ggatttggta
     8521 tgtttgtcgt cacccttgcg tcagccatta tcgttctcta tgccaatagt tttgtcatga
     8581 agaaccgttc caaggaacta ggaatttatg gcatgttggg cttggagaag cgtcatctta
     8641 tcagtatgac ctttaaggag ttagtggtat ttgggattct aactgttgga gcgggtatcg
     8701 gtattggagc cttgtttgac aagttgattt tcgctttcct actcaaactg atgaaattga
     8761 aggtggaact ggtcgctacc ttccagatga aagttgtcat tacagtactt cttgtcttcg
     8821 gtttgatttt cctaggcctc atgttcctga atgcccttcg aatcgcccgt atgaatgccc
     8881 tccagctctc acgtgagaaa gctagcggag agaaaaaagg tcgcttcctt cctctccaaa
     8941 ctattcttgg ttccataagt ttagggattg gatattatct tgcccttacg gtaaaagatc
     9001 ctcttacagc cttaacaacc ttcttcatag ctgttttact ggttatcttt ggtacttatc
     9061 ttttgttcaa tgcagggatt accgttttcc ttcaaatctt aaagaaaaat aagaaatact
     9121 attaccaacc taataatctc atatctgttt ctaacttgat tttccgtatg aagaaaaatg
     9181 cagttggact agcaactatc gctattttgt caacaatggt tttggtaacc atgtcagcag
     9241 cgacaagcat tttcaattcc gcagaatcct ttaaaaaagt tctaaatcct catgattttg
     9301 gggtttcagg gcaaaatgtt gaaaaagaag atttggacaa actcttgagc cagtttgcaa
     9361 gtgacaaagg ttataagatt aaagagaaag aagtgcttcg ttacagtaac tttggtattg
     9421 caaatcaaga aggaaccaag ttaactattt ttgaaaaagg acaaaaccgt gtccaaccaa
     9481 aaacagtttt catggtattt gaccaaaaag attatgaaaa tatgactggt caaaaactgt
     9541 ctctatcagg aaatgaggtc ggtctctttg ccaaaaatga cggactgaaa ggacagaaag
     9601 ctctaactct aaatgatcat caattttctg tcaaagaaga atttaataaa gatttcattg
     9661 tcaaccatgt tccaaataag tttaatatct tgactactga ttacaattac cttgttgttc
     9721 ctgatttaca agcctttttg gatcaattcc cagattcggc tatctataat cagttttacg
     9781 gtggtatgaa tgtagatgcc agcgaagaag aacaactcaa ggtcgctgag gagtatgaaa
     9841 actacctcaa tcaatttaat gctcaattag acacagaagg tagctatgtt tatggtagca
     9901 ctctagcaga tgctagtgct cagatgagtg ccctctttgg tggtgtcttc tttatcggta
     9961 ttttcctatc cattatcttt atggtcggaa ctgttctggt catctactac aaacaaattt
    10021 ctgaaggcta cgaagaccgt gaacgcttta ttatcttgca gaaagtcggt ttggaccaaa
    10081 agcaaatcaa gcaaaccatc aacaaacagg ttttaactgt tttcttcctt cctttgctct
    10141 ttgccttcct acatctagcc tttgcctacc atatgcttag cctgatttta aaagtgattg
    10201 gtgtactgga tacgactatg atgttgattg tgaccttgtc tatctgcgct atcttcctca
    10261 tcgcctatgt gctgattttt atgattactt caagaagtta tcgcaagatt gtgcaaatgt
    10321 aaaaaagata cctcgacttc aaaatcgagg tatttcttgt attctaaatg ctgaaaagtt
    10381 gttcgagcag gaaggtaact cccatggtca agagaccaat agcaaggttc cgaatcatag
    10441 ctgttttggt tggggctttt ccaagtctag cacttgtgta accagtgaga agaagggcca
    10501 caccgacaat aaggacggta gcagggatgc ggtaatcact tggaaaaatg gtcactgaca
    10561 gcattggagg caaacttcta aggaaaaagg caacgaagct agaaatggca gcgtgccaag
    10621 gattggtaaa ttcttcatac tcaatcccat atttttcctc taccagagcc ttgagtggat
    10681 ttttaagaaa gatcttatta gtcaagagtt gggcagaagt tttgaattct ccattttgga
    10741 tataagaagc atagagggat tttttggcta gttccctatc ttggtctagc aagagttttt
    10801 ctcgcgaaac ggcagcttcc tcggtatctt ttggagttga aacggataca tattctccac
    10861 cagccattga aaaggcacca gctaagatag ccgcaaaacc tgataaaaag ataatccaga
    10921 tattgctcgt ggcactggca actccgataa ccacaccagc aatggaaata attccatcgt
    10981 tagcatcaag aacacccgca cgcaggatat ttaaacgacc tgcaaaattt gaatcaattt
    11041 cgtgatttgt ttctgacgct aaatttcaag ttcaagttag ccatccagaa gtcttctctg
    11101 ggtgacttgt agtccaagca ttttttagga tagttgttaa tccacttttc gatgaatgcg
    11161 acttctttgg gagtcatttt cttgattccc ttaggtaacc atctacgaat gagcctgttg
    11221 tgattctcat tagttcccct ttcccaagag gcataggggt gcgcataata gatgtgctcc
    11281 tcagaaaata catcaaacaa gcgattgaat tccgttccat tatctgccgt gatggaaaga
    11341 atcttgtgtt gttttaagat gagttttaga gcctgattga ccacatcagc acttttattt
    11401 ggaatcaatc ggatgatctg atgtctactc tttcgatccg tcaagacaag caaacagtag
    11461 tttttcgctc tcgtaagtag aaccgtatca atctcataat gcccattctc caagcgaaga
    11521 ttgatagctt cagaccgctg ttcgatggat tgaccagcag atttaaagtt ggtgctagcc
    11581 tgtttcttaa gcgcttttcc ttttctaggg taaagcagat cctgtttgct taaccccaat
    11641 tttccatgat gaatccaata gtaaatggtt gaaattccca cgttaacccc tttaaccatc
    11701 accatcattt caggcgaaaa tttttggtta tgatagtgga gaatcttttc ctttagttcc
    11761 ttggtcacgc ttgatttcct gaccgagcgc ttgcgattgt tttcataaga ctgttgagca
    11821 tagtcggcag aataaacctc tttgaagcgc ccttttccaa gacattgtcg gactgtccca
    11881 cgcttgattt cagtgtggat agtttgagga acttttccaa gcagagaggc aatttctcta
    11941 tttgatttcc cttctttttt ccatctttcg attaagcgac ggctatcgat tgtcaaatgt
    12001 ttggcttttg tagtataatt gtcttgcatc tctgtgcctt tcttgtgttt gtggttgaac
    12061 aacaagtata acacagaggt gttttcttat gcctacaaga gctatcagct agttgaacca
    12121 tctaattttt aggagggctg ggtggctaac ttcattatag aactttcatt tacgaacata
    12181 tagtaaaatg aaacaagaac agaacaaatc gatcaggaca gtaaaatcta tttctaataa
    12241 tgttttagaa gcagaagtgt actattctag tttcaatcta ctatattttt gttttttatc
    12301 aaaaaatact ttacaagttc ttaaaaacat gatatagtaa taaagcttag aaaatgagat
    12361 gatgttttct agcaaatata aacccgagta aaaaatgcct acggacaggc agggttgaat
    12421 gccgaagcgt ggttgaaaag ccacattatt gatagggtta aaagcctact tttataagtt
    12481 gatgttagga cacttgtcct aattcataaa tttttagtgt ggtgaaagca cacgtcatct
    12541 tgtgaaacga tcaataaagt acgtaatatt tgctactaga gagttaggaa acatcgggaa
    12601 cagacatact caacagaaac caaaataaac acgtcagaag attgcagagc aggtgaaaac
    12661 ctgctctttt ttcatgagtc aacctttagt tccttagttt tcataaggtc ctaaaaatat
    12721 tgaaaggagt atgttttgaa agagttagat caaaaccaag ccccaattta tgaagccttg
    12781 gtgaagttac gcaagaaaag gattgttccc tttgatgttc caggtcacaa gcgtggacgg
    12841 ggaaatccag aacttgtcga actcttagga gaaaaatgtg taggcattga tgtcaattcg
    12901 atgaaaccct tggataattt aggccatcct atttcgatta ttcgtgatgc agaggagctg
    12961 gctgcagatg cttttggagc tagccatgcc tttctaatga ttggtggaac aacttcatcg
    13021 gtgcagacta tgattctggc aacctgcaag gcaggagata agattattct gccacgaaat
    13081 gtccataaat ctgctatcaa tgcgttggtt ctatgtggtg ccattcccat ctatatcgag
    13141 atgagtgtag atcctaagat tggtatcgct ttaggtcttg aaaatgaccg agtagcacag
    13201 gccataaagg accatccaga tgctaaggct atcctaatca acaatcctac ttactacggc
    13261 atctgttcag acctaaaggg gttgacagaa atggctcatg aagctggcat gatggtttta
    13321 gtagatgaag cccatggagc gcatttgcat ttcactggta aacttccaat ttctgctatg
    13381 gatgcaggag ctgatatggc agcagtttcc atgcataagt ctggtgggag tttgacacaa
    13441 agttcgcttc ttttaatcgg ggagcagatg aatcccgagt acgttcgtca gattataaac
    13501 ctgacccagt ctacatctgc ctcttactta ttgatggcta gtttggatat ttcacgtcgc
    13561 aacttggccc ttcgtggtaa agagtcgttt gaggaagtca ttgagctatc cgagtacgct
    13621 cgtcatgaaa tcaatgccat tggcggttac tatgcttact caaaagagtt aatagatggt
    13681 gtgtcggtct gtgattttga tgtaaccaag ttgtcagttt acactcaggg aataggctta
    13741 acaggtatcg aggtttatga cctcttgcga gacgaatacg acattcagat cgagtttggt
    13801 gatatcggca atatcttggc ctatatttcc atcggcgacc gcatccaaga catcgagcgc
    13861 ttggttggtg ctctggctga tattaagaga ctctattcac gagatgggaa ggacttaata
    13921 gctggagaat atattcagcc cgagttggtg ctgtctccac aagaagcctt ctattcagag
    13981 agaaaaagtt tgaccttaga tgagtctgtt ggacaggtct gtggagaatt tgtcatgtgc
    14041 tatcctccag ggattcctat cttggctcct ggtgaacgca ttacacgaga aattgtagac
    14101 tatatccaat tcgccaagga acgtggttgc tccctccaag ggacggaaga tccagaggtc
    14161 aatcatatca acgttattaa gagaaagaca aactataaga aaagtcaata gttttatcta
    14221 aactatttct tatttcaatt tgatgatttg gcgatgattt tagagcacgg caaaaagccc
    14281 ttgaattaga agcggtcaat cgcttaattt ctatcagctt atcaaatcct gcctcaatcc
    14341 ttttctgagg attagggtag cgtgtcaaga gttggtaggt atattctgaa tgctttccaa
    14401 cgattttatc caactcagga aagatgatat caagacaacg agtgtattgt actttccaat
    14461 cagact
//
LOCUS       DAYYYC010000051        14440 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.051, whole genome shotgun sequence.
ACCESSION   DAYYYC010000051 DAYYYC010000000
VERSION     DAYYYC010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14440
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.051"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(<1..589)
                     /locus_tag="ACHBV5_001698"
     CDS             complement(<1..589)
                     /locus_tag="ACHBV5_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HFM9967459.1"
                     /translation="MTPIKDKVRRVKTPMMVNPDTDLTISSVQQDYFSLALIGFSLLT
                     GDFLSFSKGDQKTGLSAFIKICHLIKIARLDNKITKQQEYWLYDLLMMSQGEKIQKIK
                     QLKQVTSDILLNTPDFSSYFEKYNFKEEAENIKSYLLAKSMDKSGRLFPSNEFGEFVS
                     PVSFQHGFGGVLFFMNKYYVEEDENTVKEWLTKLEN"
     gene            complement(663..1655)
                     /locus_tag="ACHBV5_001699"
     CDS             complement(663..1655)
                     /locus_tag="ACHBV5_001699"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HFM9967460.1"
                     /translation="MDLLEKECLKCDKNFQQGDIWNYYYLSDKMPAQGWKIHISSQIK
                     DAVNIFKIVYKLSQLNNCSFKVVKNLEELKKINSPREMSPTANKFITLYPKSESEAKS
                     MICNLTNRLSEFKAPKILSDYQCGMHSPVHYRYGAFLKKQAYDEKNKKVIYLLLDEKR
                     KNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVSSKDSAINKYKMEKIIKRSNK
                     GNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDIKNEAHMLKKLADKSYTTNLT
                     DEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKTLDNIVNIVSYIHKLGI"
     gene            2204..2881
                     /locus_tag="ACHBV5_001700"
     CDS             2204..2881
                     /locus_tag="ACHBV5_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFM9967461.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLCKEVSPVFVQKWQKEAVKLEFALGQIPDKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            2868..3665
                     /locus_tag="ACHBV5_001701"
     CDS             2868..3665
                     /locus_tag="ACHBV5_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFM9967462.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLEIEETTYLQETGPERGIGRIGNIQPQTFGELAQHVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            3682..4785
                     /locus_tag="ACHBV5_001702"
     CDS             3682..4785
                     /locus_tag="ACHBV5_001702"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFM9967463.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            4855..4983
                     /locus_tag="ACHBV5_001703"
     CDS             4855..4983
                     /locus_tag="ACHBV5_001703"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967464.1"
                     /translation="MDRTDEVSSKHCFEVVDRTDEVSNHTHGKATLTWFELDFRRV"
     gene            5086..6105
                     /gene="galE"
                     /locus_tag="ACHBV5_001704"
     CDS             5086..6105
                     /gene="galE"
                     /locus_tag="ACHBV5_001704"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFM9967465.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            6110..6667
                     /locus_tag="ACHBV5_001705"
                     /pseudo
     CDS             6110..6667
                     /locus_tag="ACHBV5_001705"
                     /inference="COORDINATES: protein motif:HMM:NF025025.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            6851..7042
                     /locus_tag="ACHBV5_001706"
                     /pseudo
     CDS             6851..7042
                     /locus_tag="ACHBV5_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            7217..7861
                     /locus_tag="ACHBV5_001707"
     CDS             7217..7861
                     /locus_tag="ACHBV5_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967466.1"
                     /translation="MLSKEEYIEEIGLIEKQNYVEVELYPLVADIINPTLKNSLSKRY
                     VFGRRKSNMGQIYYGLSNFPDIVILDKNYQNKARKSIEIEEWKKLRGCVEIKSLKHDL
                     ITEEKIKSTISNSFEHITGEMGQLIGDLLWYKKVIYTNGIEWRFLSLDDKEEIDNTIV
                     QVVNKRIETEEAGNSFDWWKNIKDLSFNYTDIYLSKDCIQEWDEFVKKVKEIEW"
     gene            7900..8001
                     /locus_tag="ACHBV5_001708"
                     /pseudo
     CDS             7900..8001
                     /locus_tag="ACHBV5_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(8052..8258)
                     /locus_tag="ACHBV5_001709"
     CDS             complement(8052..8258)
                     /locus_tag="ACHBV5_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFM9967467.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDILEAVKNCPTRALIGNQEA"
     gene            8310..8786
                     /locus_tag="ACHBV5_001710"
     CDS             8310..8786
                     /locus_tag="ACHBV5_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFM9967468.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKGFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMVTGSWFANPGDVIKIK"
     gene            8795..9466
                     /gene="cmk"
                     /locus_tag="ACHBV5_001711"
     CDS             8795..9466
                     /gene="cmk"
                     /locus_tag="ACHBV5_001711"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFM9967469.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            9597..9935
                     /locus_tag="ACHBV5_001712"
     CDS             9597..9935
                     /locus_tag="ACHBV5_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFM9967470.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            9938..10567
                     /locus_tag="ACHBV5_001713"
     CDS             9938..10567
                     /locus_tag="ACHBV5_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HFM9967471.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            10807..11958
                     /locus_tag="ACHBV5_001714"
     CDS             10807..11958
                     /locus_tag="ACHBV5_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFM9967472.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            12271..13020
                     /gene="truA"
                     /locus_tag="ACHBV5_001715"
     CDS             12271..13020
                     /gene="truA"
                     /locus_tag="ACHBV5_001715"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFM9967473.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            13010..13783
                     /locus_tag="ACHBV5_001716"
     CDS             13010..13783
                     /locus_tag="ACHBV5_001716"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFM9967474.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            13761..14222
                     /locus_tag="ACHBV5_001717"
     CDS             13761..14222
                     /locus_tag="ACHBV5_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFM9967475.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     AIIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         4266 a         2576 c         3100 g         4498 t
ORIGIN      
        1 aattttctaa tttcgtaagc cattctttaa cggtattttc atcttcctca acataatatt
       61 tattcataaa aaataaaact cctccaaaac catgttggaa agaaacagga cttacgaact
      121 caccaaattc atttgacgga aacaaacgac cagatttgtc catagattta gccagtaagt
      181 atgattttat attctcagcc tcctctttaa aattatattt ttcaaaataa cttgaaaaat
      241 ctggagtatt taaaagaatg tcacttgtaa cttgtttcaa ttgctttatt ttttggattt
      301 tttctccctg gctcatcatt aataaatcgt atagccagta ttcttgttgt ttagttattt
      361 tattgtctaa tctagctatt tttattagat gacatatttt tataaaggcc gataatcctg
      421 ttttttgatc accttttgaa aaggataaaa aatcacctgt taataaagaa aatccaatta
      481 gtgctaaact aaaataatct tgttgaactg agctgatagt taggtcagta tctggattaa
      541 ccatcattgg tgttttaact cgtcttacct tatccttgat aggagtcatt gtctccaagt
      601 ctattaatgt tatatcacct tttttggtat atataaaatt tgtaggagct atatctacaa
      661 ttttatattc ccagtttatg gatgtaactt actatattca caatgttatc cagtgttttt
      721 tctctaatat ttaaggagtg ttctgtttct cgaataaatt cttcaaagtt taacccgtca
      781 acttgttcct gaacaagaaa ataatcatcc acgatataaa attcatcagt taaattagta
      841 gtataacttt tatcggctaa tttttttagc atgtgagctt cattttttat atcatcaaga
      901 gctgtccatt ctccttcagc atcataattc acaaaaggtc ttgactgctt gatgattact
      961 ttttgcccgt ccgattttct aattgcccga taaacatttc ctttatttga tctcttaata
     1021 attttttcca ttttgtattt atttattgca gagtccttac ttgaaacttc acatgtggtt
     1081 tgaaaataaa tccttttttc ttcttctgaa aataaatcca ttttccagct aggaagacta
     1141 gggaaatttt gtctcttatc ttctacatag ttcttccttt tttcatctag caataaatag
     1201 atgacttttt tatttttttc atcataagct tgttttttta aaaaagcccc atatctataa
     1261 tgaactggag aatgcattcc acattgatag tcagatagta tttttggagc cttaaattct
     1321 gacagtctat tcgtaagatt acaaatcata ctcttagctt cagattctga cttaggatat
     1381 agagttataa atttgttagc agtagggctc atttccctag gggaattaat tttttttaat
     1441 tcctctaaat ttttaacaac tttaaagcta caattattta gttgggatag tttatacaca
     1501 atcttaaaaa tatttacagc gtcttttatt tgggagctta tgtgtatttt ccacccttgt
     1561 gcaggcatct tatctgataa ataatagtaa ttccaaatat caccctgttg gaaattttta
     1621 tcacatttta aacattcttt ctctaataaa tccataacaa actcctaatt attaaaatag
     1681 gctagagaca cagcactagc ctattccgta agtaaagcta cttattttat ataaaatata
     1741 actagcgacc tgtaattaaa caagtaaaag aacaatactt agggagacct gtgacaatga
     1801 tatcttcctc tggaagtagt tctaattcaa acaatgtttg ttccatgact gtatcctcct
     1861 gttatgataa attccagaaa gcatagagca aattcgtggt tcgtctgact aaatttctta
     1921 tctgaacacc accttcaaat acaaatttta gtcaaacttt tattttttct aactttctaa
     1981 ttatattcta ccatgtgttt ttatatgtca agaattttct gaataaactg tttatttttt
     2041 attttttgac atttttgcaa attgtttaaa atctttcaat tggattcact tattacttta
     2101 ggacattgaa acttctttcg ccagaggtgc ttatattact gggaagttga agattgaaat
     2161 gtggtataat aagaggtaat agagttttgg aaagtgagag aagatgattt caaagagatt
     2221 agaattggta gcttcctttg tgtcacaggg ggctatttta ctagatgtgg gaagtgacca
     2281 tgcttatctg cctatcgagt tggttgagag aggccaaatc aaaagcgcta ttgcaggtga
     2341 ggtggtggaa ggtccctatc agtctgcggt taaaaatgtt gaggctcacg gcctaaagga
     2401 gaaaatccaa gtccgtttag ccaatggctt ggcagctttt gaagagactg accaagtgtc
     2461 tgtcattacc attgctggca tgggtggtcg tttgattgct aggattttag aagaaggttt
     2521 ggggaagtta gctaatgtag agcgtttgat cctccagccc aataatcgtg aagacgactt
     2581 gcgtatctgg ctacaggatc atggattcca gattgtagca gaaagcatct tagaagaagc
     2641 tggaaagttt tatgagattt tggtggtgga agcaggacaa atgaagctat cagccagtga
     2701 tgttcgcttt ggaccgttct tgtgcaaaga ggtcagtcca gtctttgtcc aaaaatggca
     2761 aaaagaagct gttaagctag agtttgccct cggacaaatc ccagacaaaa atctggaaga
     2821 acgtcaagtt ctagtagata agattcaagc catcaaggag gtgctccatg ttagcaagtg
     2881 aagtgatcca agcttatgaa gccttttgcc ctcaggaatt ttctatggag ggagacagcc
     2941 gtggtctgca aattggcact ttagacaagg gtatccaaag ggtcatggtt gccctcgata
     3001 ttcgtgaaga gacagtggca gaggccattg aaaagggtgt ggacttgatt atcgtcaagc
     3061 acgcgcctat ctttcgtcct atcaaggact tgcttgccag ccgtccgcaa aatcagattt
     3121 acatcgacct gattaagcat gacatcgcag tttatgtcag ccataccaat attgatatcg
     3181 ttgaaaatgg gctcaatgac tggttttgtc agatgctaga aatcgaggag acgacttatc
     3241 tgcaggaaac aggtccagaa cgtggaattg gacgtattgg gaatattcag cctcagacct
     3301 ttggagaatt ggcccaacat gtcaagcaag tctttgacct agatagcctt cgaatggtgc
     3361 attatcaaga gaatgatttg cagaagccta tttcaagagt agcaatttgt ggtggaagcg
     3421 ggcagtcttt ctataaggat gctttggcaa agggggcaga tgtctatatc actggtgata
     3481 tctactacca tactgctcag gatatgctgt ctgatggctt gttagcattg gatccaggtc
     3541 actatatcga agtgcttttt gtggaaaaaa tcgcagcact ccttactcaa tggaaagaga
     3601 aaaaaggctg ggaactagag attttaccta gtcaagcatc gaccaatcct ttccgtcata
     3661 tctagttaga aagtgaagac aatgaaaaaa gttgccatta ttggagcagg aattgtggga
     3721 gcaacagctg cctactacct ctcgagagaa agtgacctag aggtgaccgt ttttgaccat
     3781 gagcaaggtc aagccaccaa ggccgcagca ggaattatca gtccttggtt ttccaaacgc
     3841 cgtaataaag cctggtacaa gatggcgcgc ttgggggctg atttttatgt ggatttatta
     3901 gctgatttag agaaatcagg acaagaaatc gacttttacc agcgttcggg agtctttctc
     3961 ttgaaaaagg atgaatccaa tttggaagaa ctttatcaac tggccctcca gcgcagagaa
     4021 gaatctccct tgatagggca attagccatt ctgaaccaag cctcagctaa tgaattattc
     4081 cctggtttgc agggatttga ccgcctgctc tatgcttctg gtggagcgag agtagatggc
     4141 caactcttgg taactcgtct gctagaagcc agtcatgtca agctggtcaa agaaaaagtg
     4201 actctgacac cgttagcatc aggctaccag attggtgaag aggagtttga gcaggttatt
     4261 ttggcgacgg gagcttggtt gggggacatg ttagaaccct tgggttatga agtagatgtt
     4321 cgtcctcaaa aaggacaact acgagattat cagctggtcc aagatatgga agcttaccct
     4381 gttgtcatgc cagaagggga gtgggatttg attccttttg caggtgggaa attgtcctta
     4441 ggcgctaccc acgaaaatga catgggattt gatttgacgg tagatgaaac cttgctccaa
     4501 caaatggagg aggccacctt gactcactat ctgattttgg ctgaagctac ttcaaaatct
     4561 gagcgtgttg gaatccgtgc ctacaccagt gatttctctc ctttctttgg gcaggtgcct
     4621 gacttaactg gtgtctatgc agccagtgga ttaggttcat caggcctcac aactggtcct
     4681 attattggtt accatttagc tcaactgatc caagacaagg agttgacctt ggaccctgaa
     4741 aactacccaa ttgaaaacta tgtcaaacga gtaaaaagcg aataatactc aatgaaaatc
     4801 aaagaacaaa ctaggtaact agccgcgggt tactcaaagc actgctttga ggttgtggat
     4861 agaactgacg aagtcagctc aaaacactgt tttgaggttg tagatagaac tgacgaagtc
     4921 agtaaccata cccatggcaa ggcgacgttg acgtggtttg aattggattt tcgaagagta
     4981 taagcatttt actgaaattt tatcaggtag tttaggatgg caaatgacat tccctgtcaa
     5041 aaatggtaaa ataagaaaaa ataatctgag aatcgaggaa aaaagatgca agaaaagatt
     5101 ttggtaactg gtggtgccgg ttttattgga acccacactg ttattgaatt gatccaagca
     5161 ggccatcaag ttgttgtggt ggataatctt gtcaatagca atcgtaagag tttagaagtt
     5221 gttgaaagaa ttacaggagt tgagattcct ttctatgagg cagatattcg tgacacagct
     5281 accctcagag atattttcaa gcaggaagaa ccgactggtg tcattcactt tgctggtttg
     5341 aaggctgttg gcgaatcaac acgtatccct cttgcctact atgacaacaa tatcgctgga
     5401 actgtcagcc ttttgaaagc catggaagaa aacaactgta aaaacatcat cttcagttct
     5461 tctgcgacag tttacgggga tccgcacaca gtgcccatct tggaagattt cccactttca
     5521 gtgaccaacc catacggtcg taccaagctc atgctagagg aaattttgac cgatatttac
     5581 aaagcagact cagaatggaa tgttgtcttg cttcgttact ttaacccaat cggagcccat
     5641 gagagtggtg atttgggaga aaatccaaac ggtattccaa acaatctctt gccatatgtg
     5701 actcaagtag ccgttggaaa attagagcaa gtgcaagtgt ttggagacga ttacgatacg
     5761 gaagatggaa caggtgttcg tgactatatc cacgttgtcg atttggctaa gggtcacgtt
     5821 gcagctttga aaaaaatcca aaaaggttca ggactaaacg tttataacct tggaactggt
     5881 aaaggttact cagttcttga aattatccaa aacatggaaa aagcggtggg acgtcctatt
     5941 ccttaccgta tcgtagaacg tcgcccaggt gatatcgctg cctgctactc agacccagca
     6001 aaagctaaag cagaactcgg ttgggaagca gaactcgaca tcacccaaat gtgtgaagac
     6061 gcatggcgtt ggcaaagcaa gcatccaaat ggatttgaag actaagatga tgatttcaat
     6121 catcgtccct tgtttaaacg aagaggaagt acttcctctt ttttatcagg ctctggaagc
     6181 tttacttcca gatttggaaa cagaaatcga gtatgtcttt gtcgatgatg gatcaagtga
     6241 tgggaccttg gaactcttaa aggcctatcg ggagcaaaat ccggcagtcc attatatttc
     6301 tttctctcga aattttggca aagaagcagc cctttatgca ggcttgcaat atgcgacagg
     6361 agatttggtg gtggtgatgg atgcagacct ccaagatcct cctagtatgt tgtttgagat
     6421 gaaaaatgta ctagacaaaa atgtagactt ggactgcgtt gggacacgga gaactagtcg
     6481 ggagggagaa cccttctttc gcagtttctg tgctgttctc ttttatcgcc tcatgcaaaa
     6541 aatcagccca gtagctctgc cgtcgggtgt ccgtgatttt cgtatgatga gaaggtctgt
     6601 agtcgatgcc attttaagct tgaccgagtc caatcgtttt tcaaaggggc tcttcgcctg
     6661 ggtgggtttc aaaacctact atttggacta tccaaatgtc gaaaggcagg ctggcaagac
     6721 aaattggagt tttaggcaac tctttttcta ctccattgaa gggattatta atttttcaga
     6781 ttttcccttg attatagcct ttgtagctgg tctcctatct tgttttcttt ctctgctgat
     6841 gacctttttt gttgtggttc ggaccctcat tttgggcaat ccgacatctg gttggacctc
     6901 tctgatggct gttattctct ttcttggagg tattcaactc ttgaccattg ggattctcgg
     6961 caagtatatc agtaagattt atttagaaac caaaaaaaga ccgctttatc ttatcaaaga
     7021 aaaaagttat catagatcat gaaaaagtag gagttatcta gcgcagtcac ttttttgtaa
     7081 ttataattct tttggtctgg aacttgagtg atttttaaaa aaattaggga tttgacatga
     7141 tataaatgaa ctatgtggaa taaatttact gcaaagacga taacttaata aataaaaaat
     7201 tcaggagggt tattttatgc taagtaaaga ggagtatatt gaagaaatcg ggcttataga
     7261 gaaacaaaat tatgtagagg ttgaactgta tcctttagtt gctgatataa ttaatccgac
     7321 tttaaaaaat agtttatcaa aaagatatgt cttcggaaga agaaagagta atatggggca
     7381 aatatattat ggtctaagta attttcctga tatagttatt ttggataaga attatcaaaa
     7441 taaagccaga aaaagtatag aaattgaaga atggaagaaa cttcgaggat gcgtggaaat
     7501 taagagttta aagcatgatt taattacaga ggaaaaaatc aaatcaacca tatcgaacag
     7561 ttttgaacat ataactggag agatgggaca acttattgga gaccttttat ggtataaaaa
     7621 agtaatttat acaaatggaa ttgaatggag atttctaagt ttagatgaca aggaagagat
     7681 agataataca attgttcaag tagttaacaa aagaatagaa acagaagaag cgggaaattc
     7741 ttttgattgg tggaagaata ttaaagattt atcgttcaat tatacggata tatatttatc
     7801 taaagattgt atacaagagt gggatgaatt tgtaaagaaa gtaaaggaaa tagaatggta
     7861 ggagtctatt ctcattgaga aatttagatt ataagtcgca gtaagattta tttagagact
     7921 aaaaaaagac cactttatct tatcaaagaa aaaagtgacc ttcctgattt tacagaaaaa
     7981 aataaagtga aaagactata attttacatg gaaatgtgct aaactagagg gagtggatta
     8041 tcgccattga tttaggcttc ctggtttcca atcagggcgc gagttgggca atttttaaca
     8101 gcctctaaga tatcctgact aggagaaatt tctttttcca gttggtcagg gtcatcgtaa
     8161 aaacgcacga ttccattatc gtggtaatca aataaatcag aataagtttg gcaaagccca
     8221 caggcgatac atcgttcagg tataagtgtg attttcatgt tcatatttat attgtaataa
     8281 gaaaagtaaa aaaaaacaag gagtaaggta tggcaaaaga accgtggcaa gaagatatct
     8341 atgatcaaga agaatcaaga gcagagcgtc ggcatcgaaa ccacggaggg gctgatagga
     8401 tggctaatcg tattttgacg atcctagcta gtattttctt tgtaattgtg gtggtgatgg
     8461 tcatcgttct catctatcta tcatcggggg ggagtaatcg cacagcagcc ttaaaaggct
     8521 ttcatgattc tgatgcaagt gtagtacaaa tctcatcttc aagcagttct cagcctgagc
     8581 agagttcaga gccagaatct acttctagta gttcagaaga agctgctaat cctgaaggaa
     8641 cgattaaagt tctcgcagga gaaggggaag cagctattgc cgctcgtgca ggaatctcca
     8701 ttgctcagtt agaggccttg aatcctgggc acatggttac aggatcttgg tttgctaatc
     8761 caggtgatgt tataaaaata aaataggagc cgatatgaaa acaattcaaa ttgctattga
     8821 tggtcctgct tccagcggta agagtacggt cgcaaagatt attgctaagg attttggatt
     8881 cacctacctt gatacaggag ctatgtatcg tgcagcgacc tatatggctc ttaagaacca
     8941 attaggagtt gaagaagtcg aagcccttct agccttgttg gaccagcatc caatcagctt
     9001 tggacgttca gaaactggag accagcttgt ttttgtagga gatgtggata ttacccatcc
     9061 tatccgtgaa aatgaagtga ccaatcatgt ttctgctatt gcagcaattc ctgaagtgcg
     9121 tgagaaactg gtttctctcc aacaagaaat tgcccagcaa ggcgggattg tcatggatgg
     9181 tcgcgatatt ggaactgttg tattgccaca agcagaattg aaaattttcc tagtagcttc
     9241 tgttgatgag agagcagagc gtcgttacaa ggaaaatatt gccaagggaa ttgaaacaga
     9301 ccttgaaacc ctaaaaaagg aaattgctgc gcgtgactac aaggatagtc atcgtgagac
     9361 ttctcctctc aaacaagcag aggatgctgt ctaccttgat acaactggtt tgaacattca
     9421 agaagtagtt gaaaaaatca aagcagaagc tgaaaaaaga atgtaaatgt agaaaagccg
     9481 atagattgat atcggttttt ttctaaattt gtcaaaatgc tgattttagg gtataatagt
     9541 tgctgttcga gaaattttga ttttcaaaga atagtgaatg atgataagga gaaaccatga
     9601 acaatttacc aaattgtcca aaatgtaact cagagtatgt ctacgaagac ggtgccctac
     9661 tggtttgccc agagtgtgct catgagtgga atcctgctga agttgcagaa gtagaagaag
     9721 gtcttgtcgc tatcgatgcc aacggaaata aattgactga tggtgataca gtaactctca
     9781 tcaaggactt gaaagtaaaa ggtgcgccaa aagatttgaa acaagggacg cgcgtgaaaa
     9841 atatccgcat cgtagaaggc gaccacaata tcgactgtaa gattgatggt tttggtgcca
     9901 tgaaacttaa atcagagttt gtgaggaaga tttaagcatg tcaaaacact ataaacttgt
     9961 attttatagc cgtatcttct tgtttctagc ggcttttacg ggagtttatc ttgaaattac
    10021 taagcatggt ggttttggga tgcttctcta ttacacggtt ctgtccaacc tcttggtaac
    10081 tatttttacc ctttatcttc taaaggttat gagccgtgta ggtgaaaatt ggcaaaggcc
    10141 aagtctcttg cgcttaaaag gtggggtcac catgagtatc atgattacct gtgtgattta
    10201 ccatttcctc ttggcgccca ttgcgactaa tttctatacc ctagaaaatt tcctttgcca
    10261 ctatatcgtt cccatctggt ttttagcgga taccctcttt tttgacaaac agggtcaata
    10321 caagatttgg gatccagcag tgtggaccat tttacccttt ctgtatatga tgtttgctct
    10381 ttttaatggc ttggttctaa aactcaatat tccaaatgct aaggataatc ctttccctta
    10441 cttctttttg aatgtgaaca agggttggaa tgttgtgttt aagtggtgtc tgattatctt
    10501 tgttgcctat atggtagcag gatttatttt ctactttatc aagcaaatca agagaaagtc
    10561 atcctaatac tcttcgaaaa tctcttcaaa ccacgtcagc ttccatctgc aacctcaaaa
    10621 cactgttttg aacaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
    10681 aagatacaag ggattcattt tcgaatttaa gaaggagtct acaaaccaat gaggcttctt
    10741 cttttcttgc ttatttgata actatcaaaa aagtagaaga ttaagagaaa tatagaaaga
    10801 gatttcatga aacaattttt agaacgggcc agcattttgg ctctctccct cgttttgatt
    10861 acctcctttt ccatttcgag tgccctacca gccatgtttg actattatca gggttattct
    10921 aaggaacaaa ttgagctctt ggtgagcttg ccttcctttg gaatcatgat gatgttactg
    10981 ctaaatggtt tcttagaaaa aatatttcct gagcgcttac agattagttt gggcttgctg
    11041 attttatcat tgagcggtac agctcccttc tggtaccaag cctatccctt tgtctttgga
    11101 acacggcttc tctttggttt gggtcttggg atgatcaatg ccaaggccat ttctattatc
    11161 agtgaacgct accaaggaaa aaggcgaatt cagatgttag ggctacgcgc ttctgcagag
    11221 gtcgttggag cttctctcat taccttggcc gtcggtcagt tgttggcctt tggttggaca
    11281 gctatctttc tagcctatag tgctggattt ttggtgctgc ccctttatct gctctttgtc
    11341 ccttatggaa aatcaaagaa agaagtcaag aaaagagcga aggaagcaag tcgtttaact
    11401 cgagaaatga aaggcttgat ttttacctta gctatcgaag cggcagttgt agtttgtacc
    11461 aatacagcta ttaccatccg tattccaagt ttgatggtgg aaagaggatt gggggatgcc
    11521 cagttatcta gttttgttct tagtatcatg cagttgatcg ggattgtggc tggggtgagt
    11581 ttttctttct tgatttctat ctttaaagag aaactgctcc tctggtctgg tattaccttt
    11641 ggcttggggc aaatcgtgat tgccttgtct tcatccttgt gggtggtagt agcaggaagt
    11701 gttctggctg gatttgccta tagtgtagtc ttgacgacgg tctttcaact tgtctctgaa
    11761 cgaattccag ctaaactcct caatcaagca acttcatttg ctgtattagg ctgtagtttc
    11821 ggagccttta cgaccccatt tgttctaggt gcaattggct tactaactca caatgggatg
    11881 ttggtcttta gtatcttagg aggttggttg attgtaatct ctatctttgt catgtaccta
    11941 cttcagaaga gagcttagga ttgattccta agtttttctt ttgatactca atgaaaatca
    12001 aagagcatag ttgattgagt ttggaatagt acgctgtagc tgctaaaata tttctagaaa
    12061 ttaatttgac ttttctaata gagttattca tatcttattt caatttacta tagaaagcta
    12121 gccgcaggtt gctcaaaata gtgttttgag gttgcagatg gaaactgacg tggtttgaag
    12181 agattttcga agagtatgag atttttatac ccatacaata tttgttttag gtccttgttt
    12241 acagactaat ttcttgataa aatagaggtt atgacgagat ataaagcaac tatttcctat
    12301 gatggttatg cctttgctgg ctttcagcgc cagtctcatg cgcgtagcgt tcaggaagaa
    12361 attgaaaaaa ccttgaccag attaaataaa gggcaaacca ttactgttca cggtgctggt
    12421 aggacagata gtggggttca tgccctggga caggtcattc attttgacct gccttatcag
    12481 atggatgagg agaaactccg ttttgccttg gatacccagt ctcctgaaga tattgatgtg
    12541 atttcgattg agcttgtggc agatgatttt cattgccgtt atgccaaaca tagcaagacc
    12601 tatgagttta ttgtggatag aggacgtccc aaaaatccta tgcgccgtca ctatgccacc
    12661 cactttccct acccactcga tgtggaacga atgcagattg caatcaaaaa gctagaggga
    12721 acccatgatt ttaccggttt tacagcctct gggactagtg tagaggataa ggttcgcacc
    12781 atcacagaag ctagtttaat agtcgatgag acaggacaat ttttgacctt taccttttca
    12841 ggaaatggtt tcttgtataa acagattcgc aatatggtgg ggactcttct caaaatcggt
    12901 aacaaccgca tgccagtaga gcagattgat ctcatcttgg agaagaagga caggcaactt
    12961 gcaggtccca ctgcagcacc aaatggtttg tatttaaagg agattcgtta tgaagaataa
    13021 tcgtatttta gcactttctg gaaatgatat ttttagtggt ggtggactgt cagctgattt
    13081 ggctacctat accttgaacg gcttgcatgg gtttgtagca gtgacttgtt tgacagcctt
    13141 gacagaaaaa ggatttgaag tctttccaac tgatgatacc atttttcaac atgaattaga
    13201 tagcttgcgt gatgtggaat ttgggggaat taagattggt cttctcccta ctgtcagtgt
    13261 ggctgagaag gccttggact ttatcaaaca acgcccagga gtacctgtgg tgttggatcc
    13321 tgtcttggtc tgcaaggaaa cgcatgatgt agctgtcagt gagctctgcc aagagttgat
    13381 tcgctttttc ccttatgtca gtgtgattac gcctaatctc ccagaagcag aattattatc
    13441 cggtcaggaa attaaaacct tggaagacat gaaaactgca gcgcagaaat tgcatgattt
    13501 aggagctcca gcagtcatta tcaagggagg caatcgtctt agtcaggaca aggcggtgga
    13561 tgtcttttat gatggacaga cctttactat cctagaaaat ccagttatcc aaggccaaaa
    13621 tgctggtgca ggttgtacct ttgcctctag cattgccagt cacttgatta aaggtgataa
    13681 acttttgcca gcagtagaaa gctctaaggc tttcgtttat cgtgctattg cacaagcaga
    13741 tcagtatgga gtaagacaat atgaagcaaa caaaaacaac taaaatcgcc cttgtatccc
    13801 tattaaccgc cctttctgtg gttctaggtt atttcttaaa aatcccaaca cctacaggaa
    13861 ttctaactct tttagatgct ggtgtcttct ttgcggcctt ttactttggt agtcgtgaag
    13921 gagcggtagt cggaggacta gcaagtttct tgattgacct cttatcaggc taccctcagt
    13981 ggatgttctt tagcttggtc aaccatggct tgcagggatt tttcgcagga tttaaaggaa
    14041 aaagtcagtg gttaggcctt attttagcaa ttattgccat ggtaggaggc tacgccttgg
    14101 gttctacttt gatgaatggc tgggcagcag ccctcccaga aattctacca aatttcatgc
    14161 aaaatatggt agggatgatt gtaggattta ttcttagtca aagtatcaag aagattaagt
    14221 aatactcttc gaaaatctct tcaaaccacg tcagcttcca tctgcaacct caaaccactg
    14281 ttttgagcag cctgaggcta gctttctagt ttgcactttg attttcattg agtataaaga
    14341 ggttgagtaa aaagtatttc aaataagaaa aacgcatagt atcaggtgtt gaatgaactg
    14401 ccccccaaaa gttagacaga aaaaatctaa cttttggggt
//
LOCUS       DAYYYC010000052        14411 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.052, whole genome shotgun sequence.
ACCESSION   DAYYYC010000052 DAYYYC010000000
VERSION     DAYYYC010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.052"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(10..1299)
                     /gene="hisS"
                     /locus_tag="ACHBV5_001718"
     CDS             complement(10..1299)
                     /gene="hisS"
                     /locus_tag="ACHBV5_001718"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFM9967476.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKEA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVSYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1377..2624)
                     /locus_tag="ACHBV5_001719"
     CDS             complement(1377..2624)
                     /locus_tag="ACHBV5_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HFM9967477.1"
                     /translation="MKLLFRNPAYRILILSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(2817..3668)
                     /gene="rgg"
                     /locus_tag="ACHBV5_001720"
     CDS             complement(2817..3668)
                     /gene="rgg"
                     /locus_tag="ACHBV5_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HFM9967478.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            3792..4133
                     /locus_tag="ACHBV5_001721"
     CDS             3792..4133
                     /locus_tag="ACHBV5_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFM9967479.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            4197..4406
                     /locus_tag="ACHBV5_001722"
     CDS             4197..4406
                     /locus_tag="ACHBV5_001722"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967480.1"
                     /translation="MKIKGQTRKLAAGCSKHCFEVMDRTDEVSSKHCFEVVDRTDEVS
                     PKHCFEVVDRTDEVSNHTYGKATLT"
     gene            complement(4432..6135)
                     /gene="ilvD"
                     /locus_tag="ACHBV5_001723"
     CDS             complement(4432..6135)
                     /gene="ilvD"
                     /locus_tag="ACHBV5_001723"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HFM9967481.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(6368..7300)
                     /locus_tag="ACHBV5_001724"
     CDS             complement(6368..7300)
                     /locus_tag="ACHBV5_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HFM9967482.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGMTKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(7297..8154)
                     /locus_tag="ACHBV5_001725"
     CDS             complement(7297..8154)
                     /locus_tag="ACHBV5_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFM9967483.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(8158..9504)
                     /locus_tag="ACHBV5_001726"
     CDS             complement(8158..9504)
                     /locus_tag="ACHBV5_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFM9967484.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFITKPSAKEE"
     gene            complement(9517..9801)
                     /locus_tag="ACHBV5_001727"
     CDS             complement(9517..9801)
                     /locus_tag="ACHBV5_001727"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM9967485.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(9805..11835)
                     /locus_tag="ACHBV5_001728"
     CDS             complement(9805..11835)
                     /locus_tag="ACHBV5_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFM9967486.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            12026..13033
                     /locus_tag="ACHBV5_001729"
     CDS             12026..13033
                     /locus_tag="ACHBV5_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFM9967487.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            13036..13236
                     /locus_tag="ACHBV5_001730"
     CDS             13036..13236
                     /locus_tag="ACHBV5_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFM9967488.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            13388..13570
                     /gene="rpmF"
                     /locus_tag="ACHBV5_001731"
     CDS             13388..13570
                     /gene="rpmF"
                     /locus_tag="ACHBV5_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFM9967489.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            13586..13735
                     /gene="rpmG"
                     /locus_tag="ACHBV5_001732"
     CDS             13586..13735
                     /gene="rpmG"
                     /locus_tag="ACHBV5_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFM9967490.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(14214..>14411)
                     /locus_tag="ACHBV5_001733"
     CDS             complement(14214..>14411)
                     /locus_tag="ACHBV5_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HFM9967491.1"
                     /translation="ESGSMATGWVKDKGLWYYLNESGSMATGWFTVSGQWYYTYNSGD
                     LLVNTTTPDGYRVNANGEWVG"
BASE COUNT         4658 a         3044 c         2479 g         4230 t
ORIGIN      
        1 ctttgatttt tattgagtat aaaatcctag tttttcaaag atttctgaga agttttggct
       61 gattgtctca agtgacactt gcacttcttc tcgagtttgg ttgttcttga ccgtcacttg
      121 tccgctttcg acttcgctct ctcctagggt gatgagggtc ttagccacaa agacatcggc
      181 tgacttgaac tgagctttta gtttacggtt gaggtaatca cgctctgctt tgaaaccttg
      241 ttggcgaaga gcctgtacca attccaaggc cttgatattt gccccttcgc ccaagactgc
      301 gatatagaca tctagggcgt tttcgatagg gagggtcaca ccttgctttt caagaatgag
      361 aagcaggcgc tctacaccaa gtccaaaacc aaatccagca gtttcagggc ctccaaaata
      421 agaaaccaaa ccatcgtaac gaccacccgc acagacggtc aggtcattgc cctcaatctc
      481 tgtgataaac tcgaaaatgg tgtggttgta gtagtccaga ccacgcacca tattggtatc
      541 gatgatgtaa tctactccaa gattttccaa catctgacgc acagcatcaa aatgagcttg
      601 gctttcttca tcaagaaagt ccaagataga cggcgcattc tctactgcct ccttgtcttc
      661 tttttcctta gagtccaaga cacgaagagg attttcctcc aagcgacgtt ggctatcctt
      721 agacaaggtc tccttgagcg gtgtcaaata gtcaatcaag gcttggcggt aggctgcacg
      781 gctctcagga tttccaagag tgttgaggtg caatttgaca ccttgaatac cgatttcctt
      841 caaaaaatgg gctgccatag cgattgtttc cacatcggta gctggattgc tagagccaaa
      901 acactcaaca ccaatttggt ggaattggcg caagcgccct gcctgtggac gctcataacg
      961 gaacataggt cccatatagt agaacttgct tggcttttgc acttctgggg cgaagagttt
     1021 attttccaca taggaacgga caacgggcgc agttccttct ggacggaggg taatatgacg
     1081 gtcacccttg tcataaaaat cgtacatttc cttggttacg atatccgttg tatctccgac
     1141 agagcgactg ataacctcgt aatgctcaaa aataggcgtg cgcacttctg catagttata
     1201 gcgcttgaaa atctcacggg caaagccctc aacgtactgc cacttagcag attcagcagg
     1261 taaaatatcc tgcgttcctt ttggtttttg taatttcata gggaatcctc tttaaactta
     1321 atagtcttat tttaccacaa ataaagggat taaaacagta agaaaaaaat taggatttag
     1381 atatcatttt tgagattaag aattgtcaaa aaaatagcta gcaaggaaag accaacaaat
     1441 agcatccaag tcaactgtat attccatacg gctactagtg aaaaacaagc tgttcccaca
     1501 ggtatggata aggtaaacaa tagacctaaa aaattactag tacgagctag aacctctgga
     1561 gctagatttt tcatgagcat ggcactaatc tttggttgaa ctttaccaga cacatacagg
     1621 gtaaagaaga gaaatagcaa accaagcacg acttgattga ataaattagc caaaccaact
     1681 agactaagtc ctacggtcgc ccacatcatc aatctaggca aggactgctt cccaaaataa
     1741 tcattgcccg taaggctact gatgatgatt gctactaaaa cacagaattg attgataaat
     1801 agtgcctctg tataagaaaa attcaagaga gaatggctca aaaagaagat attataaatt
     1861 ccacccaaag cgccacccaa ggaattaata agcaagacag caaagagcat aaaaccaaag
     1921 tttttctgcc cacttttaag aaaaacgaga cgtaaatttc ggtaaattgt taggaactgg
     1981 tctttgatag aaagcttctc attttttaag ttttcaccat cagcagatga cattgacagg
     2041 ctcaatttgc tttttcctaa aaagaggata gtggctgata ctaggaaaaa gcaggcattg
     2101 attcccgcaa cgagagaaaa attgttgacc gatagagcta agagccagac tccgaaagct
     2161 tgaccaccaa tagctgaaat ataggtgatg aactgtgaaa aagaataagc ctccatcaaa
     2221 tcatcttcag ctactttttc cttaataaga ggcatacgca ggccacctgc aaaatcactg
     2281 atgatatcac taatgacatt gatcaaacac aggctagaaa aggcaaagag actagcttgc
     2341 tgaacaacta gggctgctag aaaaaataga accgcctgaa acaaaccgct atagaccatc
     2401 catttgacct tgtccctcgt gtaatctgcc cgaatcccta caaaaactgt aaagagggtc
     2461 ggaagaatca tgacaatatt cgccatagca acagcaaaag atgcttgtga caaggtcgat
     2521 gcatagacga taaagaccag gttgaaaatc gaagcaccaa aagcattgaa gaagcgtgat
     2581 aaaatcaaaa ttctataagc tggatttcta aacaatagtt tcatagataa tctcccttct
     2641 tgttcgaacc tctatatgaa gtatgactat agtatagcac ttagaaattt gagagggaga
     2701 actcttgaat atatgcaaca aataaaatga gcaaaaagaa acgatagaac ttttgtaatg
     2761 acctgagaga gggcaatagt tctatcgctt caaatttttt cttggtttgc agatattcaa
     2821 cattcggtcg tatttctata gtattcggca gatttattac agccaagcat ctcaaaaata
     2881 cggacagcat cctccatctt tttctggcct tccttgactc taccttgctt gctatcaagg
     2941 agaccttctg cccacagata aacaattcgg aaataggtct cattttcctt gtagaaatgc
     3001 tcttcgataa cacgtttaaa ataataggca ttggtaaatt cttcacactc aatactagct
     3061 aaaaagccat tcaatagtat agtatgaaaa aggtttcgat tgccagacat ttccattaga
     3121 aaatcagatt tacgtaccat ttctcgtaca tatctagtaa aaagagaaac agataaaaat
     3181 ggagaactga ctgaaaataa attgagttca tagattcccc agatctcggt agaaaacaaa
     3241 taatcatgaa ggacttttcc ttcctctgct gttaactcta ccctttcatc catgctcttc
     3301 atataagact tgataataat ggcatttaga atatgtttct gtttgttgtg agaatgggca
     3361 tgcttttgat actccctgcg atataagtcc tcaagaggtg ctatattctt tggttccaag
     3421 acatctgtaa tttcttttct caactcagaa tctgtatcat actggaaacc tctcgccaga
     3481 aagaggatct cctccacact ggcagatata ttttccagag caaatagaaa cttttccacc
     3541 gaaagctcac tctgacctgt ttcaaaacgg gacaacatag acggcgaaaa ttgtcctccg
     3601 gttgcttgtc tcagtgagat atttcttgac tctcgtaatt gtctaaagac ttttccaatc
     3661 tgctccatag acttcccctt gattccgtat tttcttcatt ttatcctatt tttcagaaaa
     3721 ttcatcaaaa acttgccaaa ttgtcagaat tatgagaaaa tagaggatat ttatcacgtg
     3781 gagggactgc tatgagagac gatatcaaaa tcaatgaccg tgctttggcc ttgcaagacc
     3841 aaattatcga aaaactagag aaagtttttg atacagatgt ggaattggat gtttacaatc
     3901 taggtctgat ttatgaaatc aatctggatg aaacggggct ctgcaagatt gtcatgacct
     3961 tcaccgatac tgcctgtgat tgcgccgaaa gcctgcctat tgaaattgtg gcaggtctga
     4021 aacaaatcga gggtatcaaa gatatcaagg ttgaagttac ctggtcgcct gcttggaaaa
     4081 tcacacgaat cagtcgctat ggccgtattg cccttggact accacctcgt taagcaggcc
     4141 aatcactttt aaagatgaaa aaagcaagcc gaaaatggct tgctttttga tactcaatga
     4201 aaatcaaagg gcaaactaga aaactagccg caggttgctc aaaacactgt tttgaagtta
     4261 tggatagaac tgacgaagtc agctcaaaac actgttttga ggttgtggat agaactgacg
     4321 aagtcagccc aaaacactgt tttgaggttg tggatagaac tgacgaagtc agtaaccata
     4381 cctacggcaa ggcgacgttg acgtgatttg aagagatttt cgagtatgag tttatttttt
     4441 acctgacttg tccatattcc agaagtctgt cacggctccg cgtgaagcag atgatacgat
     4501 gtgggcatat ttaccgagga caccacggct gtaaagtggt ggcaaggttg tttctgcctt
     4561 gcgtttttca agttcttctt cggatacggc catggaaatt tctttggtat cttggtcaac
     4621 cgtaacgata tcgccggtac ggagataggc aattggtcca ccatcctgag cttcaggagc
     4681 gatatgtcca acaaccagac cataagtacc accagagaaa cgtccgtccg tcaagagggc
     4741 caccttatct ccctgacctt taccaacaat cattgaagaa agtgacagca tctcaggcat
     4801 accaggacca cctttaggtc caacaaaacg aacaacgact acatcgccat caacgatttc
     4861 atctgtcaga acggcctgaa tcgcatcttc ttctgagtca aagaccttag ctggcccaac
     4921 gtgacgacgc actttaacac ctgatacctt ggcaactgca ccgtcaggag caaggttccc
     4981 gttcaagatg ataagcggac catccgcacg ttttggattt tcaagtggca tgataacttt
     5041 ttggcctgga gtcaagtctg caaagtcagc caagttttca gctacagtct taccagtaca
     5101 tgtgatgcga tctccgtgaa ggaaaccatt tgccaacaag tacttcataa ccgcagggac
     5161 accaccgact tcgtagaggt cttggaagac atactgacca gatggtttca agtcggccaa
     5221 gtgaggcaca cgttcttgaa tcgtattgaa gtcctcaagt gacaagtcaa catttgcggc
     5281 atgggcaatg gcgagcaagt gaagagtggc gtttgtagaa ccaccgagag ccatcgttac
     5341 agtaatagca tcttcaaagg cttcacgagt caagatatct gatggtttga gaccaagttc
     5401 caacatctta acaacagcac gtcctgctgc ttcgatatct tctttcttat cagctgattc
     5461 agctgggtga gaggatgacc ctggcaaact catccctaga acttcgatag cagttgccat
     5521 ggtattagca gtatacatac caccacagcc accagggcca gggcaggcat tacattcaag
     5581 acgtttcacg tcctcagctg tcatgtcacc gtggttccat tttccgatac cttcaaagac
     5641 agaaaccaag tcgatatctt taccatcaag atttcccggt gcaatagttc caccataggc
     5701 gaaaatagct gggatatcca tattagcaat agcaatcata gatccaggca tgttcttgtc
     5761 acagccaccg atagcgacaa aggcatccac gttgtgacca ctcatagccg cctcgatgga
     5821 gtccgcgatg atgtcacgag atgttagaga gaaacgcata ccaggcgttc ccatagcgat
     5881 cccgtctgct acggtaatgg ttccaaactg tacaggccaa gcgcctgcag atttgacacc
     5941 ttctttagcc agtttcccga aatcatgcaa gtgaatgtta catggtgtat tttccgccca
     6001 agtcgaaatc actcccacaa tcggtgtttc aaagtcctta tctgtcatac cagtcgcacg
     6061 aagcatagca cggttaggtg atttaaccat gctgtcataa atgctactgc ggtgacgttt
     6121 atctaattca gtcatcttat ccctcccatt tcagttttta ctattatagc acaattttcg
     6181 catgaagaac agaataaaaa tcttgaattt tcagaaaatt ctatacacat gtgaaatatt
     6241 taaaattaaa aacaacaaag cggattagtg cactttctga tgaccagaat atgcttttta
     6301 atccgctttc tttaaataac gtactgtaat ttttacagaa attctttcag ataagtgtat
     6361 ttaacatcta tcttgcatta taaatttcta gaaccttctc ttttatattc gattcactca
     6421 aaccatactc attaagaaga taatccattt tccctacttg accgaatctt tcttgaacac
     6481 ccatccgatg aatttttgtc attccatcat cagagaataa ttcacataaa gaactgccaa
     6541 ttccacctat ctgattgtgg ttttctacag taaatatagt ttttccactt aacattgttt
     6601 ttatctgttc tggtatcggt ttgattctaa ataaatctat cacacttact gaataaccta
     6661 atttagacag ttcatctgca actcgaatac ttggagcaac cattatacca gaagcaacga
     6721 ttacaagatc ttcaccatgc cttaactcaa tgtagccctt agaaaaatct tctccacctt
     6781 gatacacagg aactggagct tttctaattg ttcgaatata ttttagtcct tttaagtcta
     6841 atgtctggtt caatatttca cgaaattgga tatcatcagt tgcttcaaaa atgatcgatt
     6901 taggaattaa acgtaacaat ccaatttctt caaatggcat atgtgtccca ccattcattt
     6961 ctgcagttac tcctgcatct gatccaatca cagtggcatc caattgtgcg tatccaagag
     7021 aaataaataa ttgatcaaat actcttcgtg aagcaaaagg accaaatgta tgaagataag
     7081 gtctaaaccc ctgaatagac aagcctgctg caaggccgac catttctgct tccataatcc
     7141 caacattcac ataacggtct ccaaaatcct tttcaagatt attagtagcc atcgaacttg
     7201 acaaatcggc ttctaagact actatatcag aataactttg attagcctct aaaaggaagt
     7261 ctctatatac atgccgtaat tctttcgtgc ttctcatcat tctgtttcct ccaattcctg
     7321 acttaatctt tctacaactg aagttaacat ttgtctctcc tctacagtag ggcgaagatg
     7381 atggttggat ttcatttctt ccagctcttg aaccccttga cctttaatag tatctaatac
     7441 aatgcactta ggtgatgaat tatttgactg ttttaattgg acaatccctt cataaatttc
     7501 tctaatatct gaacccttga ccctaatgga ttcaaatcca aatgctgaaa atttttctac
     7561 gaaatcacct ggattacaaa tatcctttgt aaaaccatct aattgttttt tgttatcatc
     7621 aacaaataca attaagttgg ataactgttg atgagaagca aactgtatag cctcccaaca
     7681 ttgtccctca tttaactcac catctccaac aatagcataa gtataaaagg gactctttct
     7741 tattctctga ccatatgcaa gtccagttgc aacactaatt ccttgtccta aagagcccgt
     7801 tgtcatatct atgcctggcg ttagatttct atcaggatga gacggtaatt tggttccatt
     7861 tgtatttaaa gaatataaga attctttgtc aaagaaacca ttcaaataga gtgtactgta
     7921 tagagctggt cctccgtgac cttttgataa tatgaaataa tctctatctc gtgctgcaaa
     7981 tatttctgga gtcattggca ttatttcacc ataaagcact gctaaaactt ctacgataga
     8041 cagacttcct ccgtaatgtc cgaatccaag atgattcaat gttctaagag tatttaatcg
     8101 gatgttagtc gcaaattttc ttaactcatc ttccctattt ttacttaaaa tcatccctta
     8161 ttcctccttt gcagatggct ttgtaataaa ggatactcca aacataactg ctagaataag
     8221 aacaagacca atcacaatgc ctgcttgtga gccaaattga tttaacattc ctaaaataat
     8281 tcctgataga ccaaaatctg catctgagaa agttgatcct tggaaaccaa gtcctcccaa
     8341 aactggcatt aaaaagactg gaagaaaact gattaaaata ccttgtaaaa atgctccaat
     8401 agtggctcca cgaacaccac cagatgcatt cccaatgaca cctgcagtcg ctccacagaa
     8461 gaaatgaggc acaacacctg gtaagataac aaccgttcct gaagcaatca taattgccat
     8521 acttactaaa ccaccaacaa aactagagat aaatccaatt agaactgcat tgggtgcata
     8581 agtataaaca atcggacaat ccaaagcagg ttttgaatta ggtacaagac gctctgaaat
     8641 acctttaaag gctggaacaa tttcgcccaa aataaggcga acacctgcta aaataacaaa
     8701 tacccctgct gcaaattgac ctgctaattg taaagcataa actagaccac ttgtaccact
     8761 actgatttct ttttctatat attctgaccc tgcaaagata gctacaataa tgtaaataac
     8821 tgccatggat aaagtgatac taacagtact atcacgtaaa aaagctaaac tctttggaaa
     8881 tttaatgtcc tctgttgatt ttgatttgtc accgataagg ctaccagtaa aaccactcaa
     8941 ccaatatccc aaagaactga aatgacctaa agccaccttg tcatttccag ttaattgaac
     9001 catatatttt tgaacaaatg ctggggaaat actcataata ataccgagtg ctaatcctcc
     9061 tagtaagata agaggcaagc tagtaaagcc agcaactgat aaaatgaccg caatcataca
     9121 tgccatatat agagtgtggt gccctgttaa aaaaatatat ttaaatcgag taaaacgagc
     9181 gattaagata ttgaacacca tgcctgcaaa cataatcagt gcagtagctg agccatatgt
     9241 tgttaaagct acagctacaa ttgcttcatt attcggcaca acgccagata aatgaaaagc
     9301 atgctcaaac atggtaccaa atggatttaa agaattttgt acaattcctg caccaccaga
     9361 tacaactaag aaaccaacaa aggtcttaat tccaccttta ataatatcag gtaatttctt
     9421 cttctgaaga actaatccta aaattgcaat taaagctact aaaatagctg gtgtactaac
     9481 aatatccaat atgaacttca tcataacgct agcctcctat ataagtcctt tttcttcaca
     9541 aagtttagta attaattctc gtagttcatc catatcaata atactattta agatacgaac
     9601 atctccaaga tgactagctg aatcagctag atcacgacca acaatccaaa tatcagctgc
     9661 atttggatct gctccaccta aatcataatg ttcaacttct acatccgaaa cattcaaatc
     9721 actcaataca gattcaatat tcatctgtac cataaaactt gaacctaatc ctgaaccaca
     9781 agctgtacca atttttaaca ttatctaatc ctcctgttta attatcattt taatgtcatc
     9841 atagtttttt gatgatatta aagtttgaac atgattttta tctcttaaaa ttgttgttaa
     9901 atgtgacaaa gcctttaaat gactctcatt atcaatggct gcaatacaaa tcaacaatct
     9961 tacctcttgt tctggattat ccaataaata aatcggttct tccaaaacta acattgacat
    10021 tcctatttca ttcacacctt catctggccg agcgtgagga attgctactc ccttccctaa
    10081 attaataaaa ggcccaaact cttctacttt ttgaatcatt gcctcagggt agttctcagt
    10141 tatcttatct tgatccaaaa gcggtttagc tgctaaacga atcgcctcct tccatcctaa
    10201 tttttgcgaa ctaacctgat aggtttcttt ggtaatgagt tgttctagca ctggtacaat
    10261 ttcctttcta tcattttttt ggtaaagata attctttaac gccaatctta attccaattc
    10321 ttgtgtaata attccatatc ttttgacaat attcaggatt tgttcaatct caaaatcccc
    10381 atactctaaa ttcggaaaat cttttaacac tagttctact agttgtattg cttgctcttc
    10441 agtcatcata accgaaacta gataatttgg cttttctgtc tccaccttta tggtagaaaa
    10501 aaccatatca tagtcactac tagctttcac ctgtaaatca tcaatctttg aggttcctat
    10561 aaactcaatt tgaggaaata atgctaatag attctctttt aacatcaatg aagaactaac
    10621 accattagga caaatgattg ctgctttata gcatttttga ggcaaagtat ctgctttctt
    10681 taaataacct ccgaaatgga taacaaaata tgctgtttca ctatcaggta tgggattgtc
    10741 aatagcgtcc atcaagggca tcaaagaatc tttgactaat tcaaataaat caggataatg
    10801 ttctttaaca tgcaatacat attcatttga actaggtagg ccgaacttta atctatagta
    10861 agccggtata aggtggcggc gaagattttc tctcaatcct tccctttgtt taaaatgtaa
    10921 caaagaaata tcttccattc tacttataat agcctctgtt aattgattaa agtaaaccgg
    10981 agcaacatct acttcacctt caaagcaact tgataataaa acggtgatat agcgataatc
    11041 atcctcagaa aacaccgtat ctataattcc caaatcaacc actgtatcca ataaaatagt
    11101 cgttatatct tgaataacag gagatactaa tgtctctgaa agacatactc tttcaacatc
    11161 cctttgatac ctacacagaa tgaatactaa accgaaaagg caaactttta attgattaac
    11221 aataggtact agctgtagct tctcataata atctttaact acctgattta tcaaatcata
    11281 agttaatgaa tacccccaac tggataaaac ataatccaaa ccccaaatcc ctatggagga
    11341 ttccagcaac tcactaacca tttgaaaagc taagcggtgc ttattccact ctgaaccgtg
    11401 taaagtataa ccttttgctc tactgtaccc tagctccaaa tcattatcta acataatctt
    11461 tcttaatgat tgaatatcag ataaggttgt attcttactt actttcaaaa agtcttggta
    11521 atgattattc gatataaaat ctaatcggca aaaagtgtaa agatagatta aagctaagcg
    11581 agtcgacttt ggtaaaacca attcatccga cttaataata tctgtcaaag actgcttcgt
    11641 acgatttgat aaactatagc gaccttgttt tttatccagc actatccctt tattagctag
    11701 ataaggcact aaataatcta ttccttcttt gacttccttt ataggtaagc tcaccttaac
    11761 agataattca tataatgata gctcacaatg atccatcaaa gtcatcaaaa taactagtgc
    11821 tctataatca aacatttctc ttcctttcta actacaatta tagtgtaaaa attataagaa
    11881 taaaagagta tttgagcaca atataatctc accttttaaa agaaattatt gggctgaaac
    11941 tttttagtga ttattttcaa ctttctattg acttttaaaa acaaagtgat atcatttaga
    12001 tatcaaataa taggaggtca ttcttatgac tgaaaaactc atcaattcaa aaccaaatgg
    12061 tgtattcgca ttgattctca ttgaattgac aatcgtactt ggtatcttta tatttataat
    12121 gggtgttggt tcggaaaaca tttttggaat tattatcgga cctttactaa tcgtaattgc
    12181 aggtctagct catgctggtt taaaagttgt caaacctcag gaagctctgg ttctgacact
    12241 ctttggtaat tatacaggta ccatcaaaga acctggtttt tactttgtca atcccttcag
    12301 cgtagcagtc aaccctgcaa accacactcg acttggacaa agtggtgatg ttagcacaaa
    12361 atctcctttt ttaggagcta aatcatcaaa tgacaatgat gtaaatcttg aaattggcaa
    12421 gaaacagatt tccctcaaag tcatgacctt gagcaattct cgtcaaaaaa tcaatgattg
    12481 cttaggaaac cctgtagaaa tcggtatcgc ggtaacttgg agagttgtcg ataccgctaa
    12541 ggcagtcttc aacgttgata actacaaaga atatctttca ttgcaatgtg atagcgccct
    12601 ccgtaatatt gtccgcatct atccttacga tgtgtctcct aatgtggata ctacgggtga
    12661 cgggcaagca gatgaaggta gtctccgtgg ctctagcgaa attgttgcta accgtattcg
    12721 tgaagaaatc caaagtcgtg ttgaggatgc tggcttggaa atccttgaag cacgtatcac
    12781 ttacctagct tatgctccag aaattgctgc cgttatgctt caacgccaac aagcatctgc
    12841 cattattgat gcacgtaaga tgattgtaga tggtgctgta ggaatggttg aaatggcact
    12901 agaacggctc aatgaagggg aattggtaga acttgacgaa gaacgaaaag ctgccatggt
    12961 ttcaaatctc cttgtcgttc tttgtggcaa tcatgatgca caaccaattg tcaacacagg
    13021 aagtctttac taaagatggc tgaagctaaa aaaaagcaga tcccccttcg actctcaaca
    13081 aagttatacg ctgcactcgc atcatgggca gaagacgact ttcgttcagt caatgggcaa
    13141 atagaatatc tcctcacaga gtgtgtcaag caacggaaaa aagacggaaa atacgtatca
    13201 gaaaccattg acgaaccatt tgagattgat atttaacacc ttctcctgtc tgccgtgtcg
    13261 gataggagaa ttttttcatc tttttttgtc aagtaacttt actttacaaa aaaaatgtgt
    13321 tatcctagta tggttgatga aaatcagtag attgaatcga atataaatac ctaaaggaga
    13381 aatcaaaatg gcagtacctg cacgtcgcac ttcaaaagcg aagaaaaaca aacgtcgtac
    13441 acactacaaa gtaacagctc catctgtaaa ctttgacgaa actactggag attactcacg
    13501 ttctcaccgt gtatcactta aaggatacta caaaggacgt aaaatcgcta aagctgcatc
    13561 agctgaataa tagaagggag atactatgcg cgtaaatatt acacttgaac acaaagaatc
    13621 tggtgaacgc ttgtacctta cttctaaaaa caaacgtaac actccagacc gccttcaatt
    13681 gaagaaatac tcaccaaaac ttcgcaaaca cgttgtgttt acagaagtga agtaagcatt
    13741 caatacgaat caatacagaa gaaaaacgct tgatcagcgt tttttctttt tgttaatttc
    13801 actatattgc aagggaaatc attcgaatga ctacattatt gaaataagaa tacggattcg
    13861 gacaattaaa agcaagagga actcaaatgt aagttggggt tccttttttg tatatttttc
    13921 aaataacgcc tctacactat ttgtagcaaa ttcatcaact acagttgtat cttagttaaa
    13981 ataagttaga atatgtaagt gagtaccaga tataccaaga catcgtcacc atctaaggta
    14041 tattcaaaat acaaaagttg accaactaga tttctgaata tccttatata tccattctta
    14101 aaattggttt aaatagcgta gtcttttaaa ctagttttga gaatccaaaa aatcttccta
    14161 catatgtaag aagatttttt agttcagaat gattagattt agctaatgga tacctatcct
    14221 acccactcac cgttagcatt gactcgatag ccatcgggtg tagtcgtgtt tactaataaa
    14281 tctcctgaat tataggtata gtaccattga ccagaaactg taaaccaacc agtagccatt
    14341 gaacctgatt catttaagta ataccataag cctttgtctt taacccaacc agtagccatt
    14401 gaacctgatt c
//
LOCUS       DAYYYC010000053        13636 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.053, whole genome shotgun sequence.
ACCESSION   DAYYYC010000053 DAYYYC010000000
VERSION     DAYYYC010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13636
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.053"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..370
                     /locus_tag="ACHBV5_001734"
     CDS             <1..370
                     /locus_tag="ACHBV5_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replisome organizer"
                     /protein_id="HFM9967492.1"
                     /translation="RQNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKSTPIF
                     YGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDK
                     DKLRQKGLNKKMNYDVGESL"
     gene            1054..1215
                     /locus_tag="ACHBV5_001735"
     CDS             1054..1215
                     /locus_tag="ACHBV5_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967493.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1307..2986
                     /locus_tag="ACHBV5_001736"
     CDS             1307..2986
                     /locus_tag="ACHBV5_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM9967494.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            3254..3820
                     /locus_tag="ACHBV5_001737"
     CDS             3254..3820
                     /locus_tag="ACHBV5_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967495.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4142..4330
                     /locus_tag="ACHBV5_001738"
     CDS             4142..4330
                     /locus_tag="ACHBV5_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HFM9967496.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4392..5150
                     /locus_tag="ACHBV5_001739"
     CDS             4392..5150
                     /locus_tag="ACHBV5_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HFM9967497.1"
                     /translation="MVVYIRQSKLPSEVSINKYHAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            5208..6062
                     /locus_tag="ACHBV5_001740"
     CDS             5208..6062
                     /locus_tag="ACHBV5_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HFM9967498.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            6174..7058
                     /locus_tag="ACHBV5_001741"
     CDS             6174..7058
                     /locus_tag="ACHBV5_001741"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFM9967499.1"
                     /translation="MKKVMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7221..8960
                     /locus_tag="ACHBV5_001742"
                     /pseudo
     CDS             7221..8960
                     /locus_tag="ACHBV5_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
     gene            9235..9690
                     /locus_tag="ACHBV5_001743"
     CDS             9235..9690
                     /locus_tag="ACHBV5_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967500.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            10135..10611
                     /gene="pezA"
                     /locus_tag="ACHBV5_001744"
     CDS             10135..10611
                     /gene="pezA"
                     /locus_tag="ACHBV5_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PezA"
                     /protein_id="HFM9967501.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            10611..11372
                     /gene="pezT"
                     /locus_tag="ACHBV5_001745"
     CDS             10611..11372
                     /gene="pezT"
                     /locus_tag="ACHBV5_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin PezT"
                     /protein_id="HFM9967502.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSSVYDSGENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            11400..11690
                     /locus_tag="ACHBV5_001746"
     CDS             11400..11690
                     /locus_tag="ACHBV5_001746"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967503.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFLVILIRLFFLVQKNILVFLC"
     gene            11684..12556
                     /locus_tag="ACHBV5_001747"
     CDS             11684..12556
                     /locus_tag="ACHBV5_001747"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967504.1"
                     /translation="MLAEAIIKNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDI
                     HPHILHGVEISAADKLHIVCIYDYEQESWVNQWLSENIISEKDGSYQHSLTIMKDFNN
                     QKIVNYIAHFNSYDILKKGSHLSGAYKRKIFSKENTRFLEFNINSKESSQQLDILYKE
                     VGVLSLGQKVVAMLDFLLAYSDYSKDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQ
                     RQIILATHNATIVTNSMTDQVVIMESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDS
                     FKHKMSIYETALSE"
     gene            13375..>13636
                     /locus_tag="ACHBV5_001748"
     CDS             13375..>13636
                     /locus_tag="ACHBV5_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1252 family conjugative relaxosome accessory
                     protein"
                     /protein_id="HFM9967505.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQE"
BASE COUNT         4900 a         1885 c         2811 g         4040 t
ORIGIN      
        1 cagacaaaat aaacagagga cattgtcctt aatgagtcca acccatgtcc gacaagagat
       61 agagatagag aaagatatag agatagataa agagagagag ggagagatag ataaaaagtc
      121 cacccccatt ttttatggag aattcaaaaa tgtaaggtta agcaaagaag aatataaaaa
      181 tctaaaagaa aaattaaact cacacacaga tataatgata aataaactat ccagatacat
      241 ggaaagcagt ggtaagacct atcaaaacca ctatgtgaca atcttaaaat ggtatgaaga
      301 agataaagac aaactaagac agaaaggttt aaataaaaaa atgaattatg atgtaggaga
      361 atctttatag ataaaaagag gtggaaaggc actattaaag actttaagtt taaaaaggta
      421 tcaaagtatg ccagagataa aaaaatataa atatgacact ttaaaggcga ttagaaaatt
      481 aaagaaatgc tagaagactt ttagatgaca gttaccaaga gggtctaatt ttcactgcta
      541 cttatgcagt aggaattgga cctttttata taagcaaatt ctatttcaaa attggttacc
      601 aagaaagact tcttttcact gttaagtata agagggtaat ttatagaatt ttgttacatc
      661 aagataaata ttttctgatg gtcaaatttt aaaaagatta ataactctcg ataaattttg
      721 aaccttaaca attgaataga ccaagacaag acgttaatta tttttggagc gtaataacct
      781 atccgtcaag atctttcggc tgaataattc ggcaaaaaaa gttctgctaa gcaaaaagaa
      841 agtgagcgat aagtaagagt ttgaatatag ggagggatac cctatccgct atgaagaaaa
      901 tgaggataat gatacttcta aggttgaagc cggctcatcc ggaatagagg cggaggtgag
      961 attcctatgt tgctaatcca aagcacttgt caatgtcaaa aaacttaatt aaacaaataa
     1021 ttattagata taaaacttta gaggaggtat atattggaca atgactggaa tggattggct
     1081 gatttaatag caaatctgat tgcaaaatat gctggtgctt tagatttaga taatctaccc
     1141 gatccaacgc cagcaaaaaa tcaagagatg aaaaatagtt ttgacatggc aaaaacacaa
     1201 attgagacgg actaataaaa gtgttataat atacttgaaa tgatagtcca aacttaaatt
     1261 aaaaaaatta tatatgatat agaaaaatta tattgaggtt aatactatgt caaaagaaaa
     1321 aataaaagta tacctctata cacgagtatc tacgtcaata cagatagagg ggtattcgtt
     1381 agaggcacaa aaatcacgaa tgaaagcttt tgctatttac aacgattatg aaattgttgg
     1441 agagtatgaa gatgccggga agtctggcaa gtctattgaa ggtagaatac agttcaatcg
     1501 aatgatggaa gatataaaat ctggaaaaga tggagtatct tttgttcttg tgtttaagtt
     1561 atcaagattt gcaagaaatg ccgctgatgt tctttctaca cttcagataa tgcaggatta
     1621 tggagttaat cttatctgcg ttgaagatgg cattgattca tctaaagatg ctgggaaact
     1681 aatgatttct gttttatcag ctgtggctga aatagaaaga gaaaacatcc gtattcaaac
     1741 aatggaaggt tgcattcaaa aagcaaggga aggaaaatgg aatggtggct ttgctccgta
     1801 tggatataaa cttgaagacg gcaagctgtt tataaatgag gaagaggcag ttgcaataag
     1861 aacgattttc gaccagtatg taaatactac gataggagcc aatgggatat ctaaatactt
     1921 agagaatcat ggaattagaa aaatcccaag acagaatggt aagaatcctt tgtttgatgc
     1981 aggtcttata agaaagatat taaagaatcc tgtatataat gggaaaatag catttggaag
     2041 aagaacttta gaaaaagttc atggtacaag aaatgaatat aagcaggttg aacaagatga
     2101 atatctaata tctgaaggga tacatgaagc tatagtttcc gatgaagttt ggcaagctgc
     2161 tcaggttaag ctaaaatctc aagcaaagaa atatgagcat gtgaataaag gaaaagatac
     2221 acgcacacac ttgctttctg gaattgtaaa atgcccgata tgtggagtgg gaatgtttgg
     2281 gaacaagtgt atcaagaaaa agaaagatgg cacaaagtat aaagattttt attactatgg
     2341 ttgtaaacat aggcagatga taagaggtca taagtgtaca ttcagtaagc aaattagaga
     2401 agaattgtta gatgatgctg ttgcagaggt gattgtcaag atagtaagta atccgaaatt
     2461 tgcttctatg atgcaagaaa aaatcaacat gaaggtggat acctctgaaa tagaaaaaga
     2521 aatagataat taccaaaagg aattgagaaa gagtcattct acaaagttta agctaattga
     2581 ggaaatagat aatttagatg ttgaagataa gcactataag agaaggaaac aggatttaga
     2641 tgatagacta tatcgtatgt atgacaaaat agatgaatta gaatcatcac taattgatgc
     2701 gaaagcaaag aaacagacta ttgaagctga aaaacttaca ggagataaca tatataaggt
     2761 tctgatctat tttgataagc tctataaagt catgaatgat gtagagcgta ggcagttaat
     2821 ttcagctttg atttctgaaa ttcaagttta tgaagaaaaa caatctaacg gacaatggct
     2881 aaaatccatt acttttaagc taccaattat agaagaaaat ctcaacatag atttggacaa
     2941 tgatgaacaa gttgaatgtg taagtttatt agagaaacgt agttaatcct caaaaggttc
     3001 cccaaacttt ttgagtccca ctgacgcatc acgctgaggc ggtatcactg cttgtacgag
     3061 ttgaagcatc agcgaagtaa aagtagatgt tcagccaatg cgacgaggtg agaccgaagg
     3121 tcgataaggt gtgttctggg tataggactc gtaaagtaag taggaaatat gatgagatga
     3181 tacagagagc ctgaattggt caggtgacgt gcttatttac attagcctga taatgaaaat
     3241 ggagagatta tcgatggtta tattggaatt gtaccaaaat gattattcta aagatttagt
     3301 agcatttgat tccatagaag atgggaaagc ctttgtggct caaatcccgg gatacactct
     3361 ggaaacagaa gatggttttg aagtggagta ttttaatcct aaaaacatac cggattatat
     3421 ggaaattatt tttaacggaa atattgttcc tttatctaaa tttatgttcg atcctgagga
     3481 aaatgtaaac attatttgga aagagatttc aaatttatcc ctcaaaaatg atagagtgat
     3541 cgaaggatat tcaaaaattg atgcatatgt cgttaacaac catgaagtta aagcctatgt
     3601 cgaaacaaga gaaacgaact atcgtaaagc aaaagacttc ttagaaagcc gcggatatga
     3661 aatcgacaga agctttttcg gaagtgaaga cggtgaagcg attctttaca gaaaaaaagg
     3721 gatcgaagtt tggcatttct tgtgtcactt agacccaatg tttgtagaga ttgaagatgt
     3781 agaaggatat gttaaagaag aagttggaga gattcaatag tcaaccaaag ttccttgtga
     3841 gtatatacct ttgctagtaa aagagtcaaa acgttataac gaaggggggg aagaaaaccc
     3901 ttgagtgtaa gtctttttct tgtttagagg gaaagtatta gagtagccgc tcataattta
     3961 tactagattt gataactgat ttgagacaga ttttatttct ataaatattg tgaaaatttt
     4021 ttaataccaa agatttaaag ttactgtgtt aaaaatcctc tccactttta aactaatgta
     4081 ttataaaagc cagttgacac aagtgttaca cctgtgatag aattaacttg aggtgatgaa
     4141 aatggcaacc gataaaaata gaataatgat tagcttggat gataaaaatc tagagaaact
     4201 tgaaaattta gtagaagatg ctagagatag aaggggaatg cgactaacaa agtcccaggt
     4261 tattgaatta ctcctaaata ccgttgatta tttcgatgat attatggggg ctatttactc
     4321 aaaaaaataa gagcaaaatt gctattattt tttacaaatt ggtgtaacac tagtgatata
     4381 ggagtgatga aatggttgtt tatattagac aaagtaaatt accaagtgag gtttcaatta
     4441 ataaatacca tgctcaagta ggtgcctact tacaaggaga agaagctgtt ttatatcaat
     4501 ctttttctga aataaaagag ttaacaagtg aagatatagt tgtagattat ataatggaga
     4561 ctagagcatt actaaaaatg atgggcttaa acgttccggt tcatgactat cctattgagc
     4621 ttaaagagtt ttatggtcga aagatttatg ctggtatttt aggagagatt gtgaatatac
     4681 ctgataattg gggaaaattt attaagccta aagctggttc aaaagtcttt actggaagag
     4741 ttgttaatgg aacccatgat ttaataggta ttggtctacc tttcgactat cctatatgga
     4801 ttagtgaggt tgtagaattc atagctgaat ggcgttgttt tgtgttagat ggtcgcgtat
     4861 tagatgttcg accctataca ggtgattatc atgcacaatt tgatgcaagt gtaattgatg
     4921 aagcgatatc atgttggaaa gatgcgccaa tagcttatgg actagatatc ggtgttactc
     4981 gcgatggcag aacacttgtt gttgaagtaa atgatggtta tgcattggga aattatggcc
     5041 tatctccttt aaaatcaatc aattttcata gagctaggtg gaaagaaatg gtaaaaccct
     5101 attttgaaaa aaatgaaatt tttaaaatcc aacaggatgt tgttttctaa aataaatatg
     5161 gtatataacc aatataaaaa gcatcaaaat gaacaaggag gaatctgatg cttggagcaa
     5221 ttattggaga tattgtcggt tctgtttacg aatggaacaa tatcaaaaca aaggactttc
     5281 ctttatttcg gaaggactgc ttttttacag atgacacggt tatgacctgt gctgttgcag
     5341 aagcaattat gaatggtgga caaaaagacg atttcattga cgcgatgaag aaatatggca
     5401 gaatgtatcc gaatgctgat tacggtgctc ggtttaatgc atggctaaac agcgataacc
     5461 gtgagcctta taatagcttt gggaatggat cagctatgcg tatttctcca tgtgcttgga
     5521 tcatggactg tggtttttat gcgaaaactg gtatgtggcc atcatctaga ggacttacga
     5581 gtctttctgc agaggtaact cataatcatc cagaaggtgt caaaggcgct atggctacag
     5641 ctgatgctat ctttctatgt cgtttttact ttggtggtta ttgtagagag tacgagcaat
     5701 caattaacga caatcctaca gagtgtaaaa gacgaattaa ggattatata gaaaaagaat
     5761 acgattacaa tctatctcaa actttagatg aaatccgtcc taactatcgt tttaacgaaa
     5821 catgtcagga aactgtccct caagccatta tcgcctttct tgaaagtaga gacttcgaag
     5881 atgcgataag aaatgccatc tcacttggtg gcgacagtga tactctcgca gcaatcactt
     5941 gtaacatagc agaggcagct tacggtattc ctgattggat caaggataag gcctattctt
     6001 acttggatga acccttaaag gatgtagtta ggcgatggga aaatagaata aaagcgtatt
     6061 aatctccagt acgtcagatt tctcttttct gtattttcat tgtataatag gattacattt
     6121 acttgcatac gacgaaatgt aaacatttct gtttaaaatt aaggataaaa tcaatgaaaa
     6181 aagtaatggt aattatcaac cctacttctg gtggcgagaa ggctttggat tacaaagaaa
     6241 agctggagaa taaagcaaaa gaatactttg aatatgttga aaccaaaatt accgaaaaag
     6301 cgctggatgc aacacatttt gctgaagaag cttctcgtga gcagtatgat gcagtggttg
     6361 tgtttggtgg agatggaact gtcaatgaag tcatttcagg tattgatgag agagactaca
     6421 ttcctaagtt agggattatc ccaggcggta cgggtaacct cattacaaaa cttttggaaa
     6481 tcaatcaaga catcgatggc gcaattgacg aactggattt tgatttaacc aataagattg
     6541 atatcggtaa agcaaatgac aactattttg gttatatctt tagtatcggt tctctgcctg
     6601 aggcgattca caatgttgaa atagaggaca aaacaaaatt cggtatttta acctatgctg
     6661 taaataccat gaagtctgtc atgacagatc aggtctttaa cattaaggtt gagacagaaa
     6721 atggaaatta tgttggtgaa gctagccatg ttttggtcct tttgacaaat tacttcgctg
     6781 ataagaaaat ctttgaagaa aacaaggacg gctatgccaa cattttgatt ctgaaagatg
     6841 cctctatatt ctccaaatta tccgtcattc ctgatttatt aaaaggggat gttgtcgcaa
     6901 atgataatat cgagtatatc aaagcgcgta atattaaaat ctcttcagat agtgaattgg
     6961 agtcagatgt tgacggagat aaatcagata acctacctgt agaaatcaaa gtcctagctc
     7021 agcgagtaga agtattttca aaaccgaaag aggattagta tatagagaaa gcctttttta
     7081 aggctttttg tatactttaa aagatagttc ctttaacaac ggacattcct tgcaaatagt
     7141 ttacaaaaat agtatactgg atttattgag tttgaaaacg tttgcgtaaa atttgaatga
     7201 atactttagg agacaaattg atggaattga gtgctattta ccataggcct gagtcggagt
     7261 atgcctatct ttataaggat aagaaactcc atatttgaat tcgaactaag aaaggggaca
     7321 ttgaaagcat caacttgcac tatggggacc cttttatctt tatggaggag ttttatcagg
     7381 atacaaaaga aatggtcaag ataacttctg gtaccttatt tgaccattgg caggttgaag
     7441 tgtcagttga ctttgcacgt atccagtatc tctttgagct cagagataca gaaggtcaaa
     7501 atattttgta tggcgataaa gggtgtgtgg aaaattctct agaaaatctt catgcaattg
     7561 ggaatggatt taagttgcct tatcttcatg agattgatgc ctgcaaggtt cctgactggg
     7621 tttcaaatac ggtatggtat cagatatttc ctgaaagatt tgccaatggc aatgctctat
     7681 taaacccaga agggacttta gactgggatt catctgtcac acctaagagc gatgatttct
     7741 ttggtggtga tttacagggg attattgatc atatggatta cttgcaagac ttgggtatta
     7801 ctggactata tctttgtccc atctttgaat ctacaagcaa tcacaagtac aatacgacag
     7861 attactttga aattgaccgt tattttggag acaaggagac ctttcgggaa ctggtggatc
     7921 aagcgcatca tcgtggcatg aaagtcatga tggatgcggt atttaatcat attggttcgc
     7981 aatctcttca atggaaaaat gtcgtcaaaa atggcgaaca gtctgcttat aaggattggt
     8041 tccatattca acaattccca gtgacaactg aaaagctagt taataagaga gacttaccct
     8101 atcatgtttt tggtttcgag gactatatgc ctaagctaaa tacagccaat ccagaggtca
     8161 agaattatct tttaaaggtt gcgacttatt ggattgaaga gtttaatatc gatgcttggc
     8221 gtttggatgt ggctaatgag attgaccatc agttctggaa ggattttcgt aaggcagttt
     8281 tagctaaaaa tcctgatctt tatatcctag gagaagtctg gcatacatct cagccttggc
     8341 taaatggaga tgagttccat gccgtcatga attatccttt atctgatagt atcaaggact
     8401 atttcttacg aggaattaag aagacagacc agttcatcga tgaaatcaat ggagagtcta
     8461 tgtattacaa gcagcagatt tcagaggtca tgtttaatct cttggattca catgatacag
     8521 agcgaatcct gtggacggcc aatgaagatg ttcaactggt taaatcagcc ttagcctttc
     8581 tctttttaca aaaaggaaca ccgtgcattt attacggaac cgagctagcc ttgactggag
     8641 gaccagatcc agattgtcgt cgttgtatgc cttgggaacg tgtatcaagt gacaatgata
     8701 tgctgaactt tatgaagagg ctgattaaga ttcggaaata cgcgtcagta atcatttcgc
     8761 atggcaagta tagccttcaa gaaatcaaat ctgatctagt agctctggaa tggaaatacg
     8821 aaggacggat cctcaaagca atattcaacc aatcaacaga agattatctt ttagagaaag
     8881 aagcagtagc actagcaagc aattgccaag aattggagaa tcagcttgtc atctctccag
     8941 atggatttgt gattttctaa aaactagttg atgaagatta tggtacattt catatcttat
     9001 atagtataat aaggctagtt actaaacttg taaaggagaa cttaaatgaa ttgtagagga
     9061 catgaaacaa gacaaagaat tgttagagat tttgaagttt agcctaaagc acatattaag
     9121 ctgttagcaa atcaacaaaa acatagtgat gcaggagcaa ctattgaaga tgaatattat
     9181 gtatttatcg ctgagagtaa aattgatggc aagaaggaag ttattcagtg ttgcatgggt
     9241 gcggcaaggg attttttaga actaattaat cacaaagggc tacctctttt taatccgctt
     9301 gtaggtgatt ctcatgtaaa taatagacaa gaatatgaca atacagggag tggaaattta
     9361 caacctgaaa agtggaatga aactgcaaag cagctttata atgctataat gtggttgatt
     9421 attttatgga atgctaagcc ggatacacct ttatttaatt ttaaagacga agtaattaag
     9481 tataaaacat atgagccttt tgaaagcagt ataaaaagag taaatactac tataaagaat
     9541 ggtagtaaag ggaaaactct gactgagatg attaatggct acagagcgga taacgatatt
     9601 agagatgaaa tttgtaactt taatattctg aaaaataaaa ttcgtgatat gaaagaccaa
     9661 caaggaaata caatggaatc ttacttttag ttattgttga attttgggta ttctataaaa
     9721 tatcctaatt gagatttaaa tagtagacta tacaatatag ttaaaatatc agtaaaaaca
     9781 acactttatt gaggtattgg atacgctttg ctaatagcct aataatcaca tgtggagtgt
     9841 tgctacaacg aaaaaggtga taatccttaa tttcaagcta ttttataagc attttgtctt
     9901 tgtagataaa ggcaattttg acaataaaaa tcctaaaagg tgaatcgtta tagatgtatt
     9961 tgtagatatt gtttgcgcat cgaaaaaatt aatacaagaa taaatattta tagctcttta
    10021 ggtgactttt atagaagtaa agtttaggat agaaaaacaa gaaataacgc accatttttg
    10081 gtgcgttatg cttttttatg ctataatgga tttataaaaa taaaggagtt tgctatgatt
    10141 ggaaagaaca taaaatcctt acgtaaaaca catgacttaa cacaacccga atttgcacga
    10201 attataggaa tttctcgaaa tagtctgagt cgttatgaaa atggaacgag ttcagtctct
    10261 accgaattaa tagacatcat ttgtcagaag tttaatgtat cttatgtcga tatcgtagga
    10321 gaagataaaa tgctcaatcc tgttgaagat tatgaattga ctttgaaaat tgaaattgtg
    10381 aaagaaagag gtgctaatct attatctcga ctctatcgtt atcaagatag tcagggaatt
    10441 agcattgatg atgaatctaa tccttggatt ttaatgagtg atgatctatc tgacttgatt
    10501 cagacaaata tctatttagt agaaaatttt gatgaaatag agagatatag cggctatttg
    10561 gatggaattg aacgtatgtt agagatatct gaaaagcgga tggtagctta atggaaatcc
    10621 aagattatac tgatagtgaa ttcaaacatg ctttagcaag gaatcttcgt tcactgacaa
    10681 gaggaaaaaa gtccagtaaa caacctatag cgattttgct tggaggtcaa agtggtgccg
    10741 gtaagactac aattcatcgt attaaacaga aagaatttca aggaaatatt gttatcatag
    10801 atggtgatag ttttcgttct cagcatccac actatttaga actgcagcaa gaatatggca
    10861 aagacagtgt agaatatacc aaagattttg caggaaaaat ggtagagtct ttagtaacaa
    10921 aattgagtag tttgagatac aatcttttga tcgagggaac tttacgaaca gttgatgttc
    10981 caaagaaaac agcacaactc ttgaaaaata agggatatga agtacaattg gccttaattg
    11041 cgacaaagcc tgaattgtcg tatctaagta ctcttatccg ttatgaagaa ctgtacatta
    11101 tcaatccaaa tcaagcacgc gcaactccaa aagaacatca tgatttcatt gtaaatcatc
    11161 tagttgataa tacacgacaa ttggaagaac tggctatctt tgaaagaatt caaatttatc
    11221 aacgagatag aagttctgta tatgattcag gagaaaatac aacttcagca gcagatgttc
    11281 ttcaagagtt actgtttggg gagtggagtc aggtagagaa ggagatgttg caggtggggg
    11341 aaaagagact taatgaatta cttgaaaaat aaacaattga tatttttagg agagtagaaa
    11401 tgagagggtt taataacaag ataaagtctg tttatcaaga actaacaaat tccaaagaga
    11461 aattcggtag ctttcacaag actttaattc atttgcatac acctgtttct tatgattaca
    11521 agctattttc taattggact gcaacgaaat atagaaaaat tactgaagat gaactatatg
    11581 atatattttt tgaaaataag aaaataaaag ttgataagac aattttttta gtaattttga
    11641 taaggttgtt ttttctagtt caaaagaata tattagtttt cttatgttag cagaggcaat
    11701 cataaaaaat ggaatagaaa tagttgtagt aactgatcat aatactacca aaggtattaa
    11761 aaagttacaa atggcagtct caatcataat gaaaaattat ccgatttatg atatacatcc
    11821 tcatatttta catggagtag aaattagtgc agcagataaa ttgcatattg tatgtatata
    11881 tgattatgaa caagaatcat gggttaatca atggttaagt gaaaatatta taagtgagaa
    11941 agatggaagt tatcaacatt cactgactat aatgaaggat ttcaataatc aaaaaatagt
    12001 taactatatt gctcatttca atagttatga cattttgaaa aaaggttctc acttatcagg
    12061 tgcatataaa cgaaaaattt tttctaaaga aaatacacga tttttggagt ttaatattaa
    12121 ctcgaaagaa tcttcgcaac aacttgatat tctctataaa gaagttggtg tattaagttt
    12181 gggacaaaaa gttgtagcca tgcttgattt tttattagca tatagtgact attctaaaga
    12241 cttcagacca ttgattattg atcagcctga agacaatcta gacaatcgtt atatttacag
    12301 gcatttagtt cagcagttta gagatgtgaa agctcaacgt caaattattt tagcaacaca
    12361 taatgctaca attgtaacaa attctatgac agatcaagtt gttattatgg agtcagatgg
    12421 agttaacgga tggattgaat cacagggata tgttagtgaa aaatatataa aaaatcatat
    12481 catcaatcaa ttagagggag gaaaagattc cttcaagcat aaaatgtcta tatatgagac
    12541 ggctttatca gagtagagtc agaaaaagta ggttagaaat ttagcctact tttttctttg
    12601 ttcgacaggc atagtgtaca tctgaggtcc aagtcctctg tggatatttg ctgcagatga
    12661 aaccaatagc gactcctaag cctgaatatc gtgaggtagg ggggatagga aggaattagc
    12721 gaaatcaagg ttctacaaac agaatcgtga cttgaagcca tatatagcgg atgaggaact
    12781 ctaaaatcca aataggtgtc gtaacctata tacgtaaatt acgagagtaa actaggaaag
    12841 atgtacggct tattccgtga gcgtttagga cgtagtacaa cgaatcatgg gagtcagctg
    12901 aacacatagt attgaagaaa tttctgtaat ggaaatggag cgaagaagtg aacaattaaa
    12961 tgaatacctc tctaattaaa tttgtcaatt ctaattcctg gtatgaaaag acagtgacct
    13021 aaaaatgtaa acgatgggag ctgatcataa atataggacg gtacatgcag tggtgttaga
    13081 gattagtccc tacttgattt gtgataactt ccccaacttt cttctgctat acttttctca
    13141 acttttaaaa atccaactaa gaattttacc tgggagtttg ggggcgtagc caccaagtta
    13201 tcttatggtt agctgtcaaa actggaaggt tttggttagc tggcgatatg attttttggg
    13261 tattgtgacc acaatgcctg agctcgcaaa gaccgaacaa ggactttaag aaatttcccg
    13321 tatgacacac ggggtcgggg tttacccgag aaaggatgaa agtgaggaaa agagatgtct
    13381 gaacagtacc gtgacattcg aaaagaggta aatctaaccg cagatgagct aaaacagatt
    13441 gaaaaaatga tggaggttga taattatcgt cacttttcac cattcgtcag ggataaaatt
    13501 ttgatgactg atgacaaaca gttagctgcc aaagaatggt tttccctttg gcagtctcaa
    13561 aagtttgaac agatcagtcg agatgtgcat ttggttttga ttatcgcaag agagaatcac
    13621 caagtgactc aagaac
//
LOCUS       DAYYYC010000054        13084 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.054, whole genome shotgun sequence.
ACCESSION   DAYYYC010000054 DAYYYC010000000
VERSION     DAYYYC010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13084
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.054"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(50..946)
                     /locus_tag="ACHBV5_001749"
     CDS             complement(50..946)
                     /locus_tag="ACHBV5_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFM9967506.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQTDIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(955..1890)
                     /locus_tag="ACHBV5_001750"
     CDS             complement(955..1890)
                     /locus_tag="ACHBV5_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFM9967507.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(1887..2612)
                     /locus_tag="ACHBV5_001751"
     CDS             complement(1887..2612)
                     /locus_tag="ACHBV5_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HFM9967508.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(2696..3331)
                     /locus_tag="ACHBV5_001752"
     CDS             complement(2696..3331)
                     /locus_tag="ACHBV5_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFM9967509.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(3333..4160)
                     /locus_tag="ACHBV5_001753"
     CDS             complement(3333..4160)
                     /locus_tag="ACHBV5_001753"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFM9967510.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKVRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDIIQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(4182..4517)
                     /locus_tag="ACHBV5_001754"
     CDS             complement(4182..4517)
                     /locus_tag="ACHBV5_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HFM9967511.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(4518..5234)
                     /locus_tag="ACHBV5_001755"
     CDS             complement(4518..5234)
                     /locus_tag="ACHBV5_001755"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HFM9967512.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWFKQADLAIG
                     DFEETINKDHYLAGYPLFNAPAEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKMKAEIERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHL
                     YVVEPSETIEKDGDKKLIVY"
     gene            complement(5377..5499)
                     /locus_tag="ACHBV5_001756"
     CDS             complement(5377..5499)
                     /locus_tag="ACHBV5_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP synthase"
                     /protein_id="HFM9967513.1"
                     /translation="MQRRQNRNQGGLAFRFMKGLVNFLGVIASGAIRDLWRYSC"
     gene            5757..6368
                     /gene="def"
                     /locus_tag="ACHBV5_001757"
     CDS             5757..6368
                     /gene="def"
                     /locus_tag="ACHBV5_001757"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFM9967514.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            6413..7141
                     /gene="rlmB"
                     /locus_tag="ACHBV5_001758"
     CDS             6413..7141
                     /gene="rlmB"
                     /locus_tag="ACHBV5_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFM9967515.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKNLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENSLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(7180..8091)
                     /gene="trxB"
                     /locus_tag="ACHBV5_001759"
     CDS             complement(7180..8091)
                     /gene="trxB"
                     /locus_tag="ACHBV5_001759"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFM9967516.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVRKIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(8157..8381)
                     /locus_tag="ACHBV5_001760"
     CDS             complement(8157..8381)
                     /locus_tag="ACHBV5_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HFM9967517.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(8459..9202)
                     /locus_tag="ACHBV5_001761"
     CDS             complement(8459..9202)
                     /locus_tag="ACHBV5_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFM9967518.1"
                     /translation="MIKISNLSKSFSGQIVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(9202..10002)
                     /locus_tag="ACHBV5_001762"
     CDS             complement(9202..10002)
                     /locus_tag="ACHBV5_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFM9967519.1"
                     /translation="MNVTTILASDWYQNLMQLIPNGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(10160..10516)
                     /locus_tag="ACHBV5_001763"
     CDS             complement(10160..10516)
                     /locus_tag="ACHBV5_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFM9967520.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(10510..11040)
                     /locus_tag="ACHBV5_001764"
     CDS             complement(10510..11040)
                     /locus_tag="ACHBV5_001764"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFM9967521.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRSNRRRSTC"
     gene            complement(11040..11534)
                     /locus_tag="ACHBV5_001765"
     CDS             complement(11040..11534)
                     /locus_tag="ACHBV5_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFM9967522.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            11669..12115
                     /locus_tag="ACHBV5_001766"
     CDS             11669..12115
                     /locus_tag="ACHBV5_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFM9967523.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            12112..12759
                     /locus_tag="ACHBV5_001767"
     CDS             12112..12759
                     /locus_tag="ACHBV5_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFM9967524.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILTASVLQYIAIVYYM"
BASE COUNT         3934 a         2997 c         2277 g         3876 t
ORIGIN      
        1 taattagatt accacgcaaa aactctctgt cacggacaaa gagtcttttt tatttttcta
       61 agaataaatc tttcaaagaa atcaaagtta cagcaaacaa tatcattgcc ataccaagaa
      121 aatcaatggg ataaaattgt tcattcatta ttaagaaggc aaagaaaatc gccgatattg
      181 gctcaattga agccaacaag cttgacttga ccggtcctat cagactggct cctttaagga
      241 aagctgtata ggcaaagaca gtcccgataa ggataatgcc tgcaaacgca aggagaaaat
      301 caagactagt cgggatatcg gtctgtagaa cccctgtaaa aggaagggcg accaaacctg
      361 ctatgaccat tcccacacca atgaccaagc tgctccccca ctttttaatc aaggctatgg
      421 gtaaaatgat atacagagca taagtcaagg cagaaaagag accccagaac agaccagcag
      481 gtgtcatgga taactggtcc aactgcccat gtgttgcgat caggaaggtt cctccgatgg
      541 cgaatatgat ggaaactatc tctcccagtg tcggtgccac cctatccttg atacagctat
      601 aaattaaaat tccgacagga caaacatact gaagcaccgt cgctgttccc gcattggtct
      661 cctgaatagc agacagatag gcgaattggt tgagaaaaag accaatcaga gcaaaaataa
      721 gaagagacag caaactcttt ctatccttta aaaagaccag tattttatcc tttgcagtag
      781 cataagccaa gagcatgaga attccaccag cgattaaaag acgcaagttg gtcaagacca
      841 gagccgaaat tccgtgtgcc attaggtatt ggccactcgt tcctgacaac ccccaagcaa
      901 taccagccac aactgttagt aaagtccctt ttaaactatt tgacatgtct ctccttactc
      961 ttctttgcga atcaagttca tcacttgatt gcggtctaat atccattgag ctctctcgtc
     1021 cttttcatag gtacgattcg ataggaaaat agtggcttct tgcttctgac gattccacat
     1081 gataaaggta cctgtatagc ccgtatggtc tagccaatct ccttccaaat tccatgctaa
     1141 agaacgttcc ttgtcatcca aaggagaaaa attttgactt aagtctcttg caaaatcatc
     1201 tgctaaatag tgttctaaaa agatttgtaa atcctttata gtcgaaaata aaccagcgct
     1261 cccagcatgt ctacccagga gacgagcctt gggatcatgc actatgcctg cctctacacc
     1321 tctaactgtt ggaacagcaa gctcaactgg cccaaacttg gtttccgtca ttccccaagg
     1381 tttccagact tgatccttta aaatcacatc caaatcttga ttaaaaattc tttccaaaat
     1441 aaagcccaac agcaaaaaat ggacatccga ataaagaaag gctggctgac ttcgtctgtt
     1501 gagatgaaac atcgcttcct ttaattcagg ggctgttaaa agatcacgat taggaataaa
     1561 aggatcaagg tctgttgcat gagtcaagag ctggcgaata gtgatgtctg gataatcact
     1621 ctcaggtaaa aaatctatta ccagtctatc aatatctaat tgacctattt cccacaagaa
     1681 ggtacaaact gtgccaaccc caacaacctt gctgacacta gctaggtcat aaactagtcc
     1741 tgcctcagtc tgcaagccat gctctgggtc actctggcct aaatagaact ctgtccattg
     1801 attgtcctta aaatacgcaa aagaggctcc gggataaatt cctgcctcga tttgttcttc
     1861 tattttttta ataatcttgg tccacttcat acttcttcaa accacaattc aacattattt
     1921 ctatctttac aaaggaagaa tttttcagac ttaggaataa aatattcagt agactcaaac
     1981 ttctggcgaa gacttgctat gtctaattca ttgaccaaga acttgagcat agataagtcc
     2041 caggtaaccg tattgtccac agtcaaatcc tgcccctgag ctggaataaa atcaagggat
     2101 gccccaattt cagatgattc caagaaactt tcgatatcag ttgggagatg taattccata
     2161 gaaatctcaa atttacttaa agaaattgat gccaaatctg tttgaaattc aggcttttct
     2221 cctacttcta ctagacttgc tctgtcatct tccgcatgaa tcaaaatcaa atcatcttct
     2281 ggtgagaaaa tttcaaaagc gtagccattt tgacctttat ataatcgatg aatcgaatct
     2341 gttttagata agattccttc aatttctaag ggattttcca ccttgacaat caatctagct
     2401 agtttttttc ttccctctac cttacgagta cgcatactgg gagcttcttc taaaaccagc
     2461 ttttcaagac ccgtttggtc acctagtgac agaaaggccg attcttctaa caaggccttc
     2521 attccaaggg tttcaatata aaatgtttca tttaattttc tattattagc ttttaaagta
     2581 ggaataatcc gtacaatctg atttacattc ataaattcct ccgtcacttt ttattttaaa
     2641 ggattttaga attttttaca agatattatg ctcaaattta acattattta gctatttagt
     2701 aaagatagtc tttcaaggat tttgacaaag cctgataacc agcaatactg aggtgcagtc
     2761 catcagttgt atattctttt ttgagttggc ctgcttggtc tgtcaaacaa tcaaatactg
     2821 gcacaaattc cacctgcata taggcagatg caagctcttg ataggcttga ttccagttct
     2881 gaattttttc attcgagcgg atatagactg cctgctggta ctcctctccc tcattgacag
     2941 gcaaaatgga aagcaattta atctctgtca atggataatc gcgagcaacg gattgaatga
     3001 tagcttcgag attattgaga gcctcattca caggaacatc ctttccgata tcatttgtcc
     3061 caatcagaag aaaaatttta tctactgctc caccatatag atgagcatca agattctcta
     3121 gtaacagtcc tgtctgatag ccacgaattc ctcgattgac aatcgtcttt gaagtcccaa
     3181 atagctcctg tagaggataa tactcgacaa tggaatcccc aataaaaaga atgtttggtt
     3241 ctacaacaga aatgtgattt aggtgacgat acttagtttg aattttttct tgttccttta
     3301 ggagccaatt ttctaataac tgtactgcca cttcattctc ctttttctaa ccagttttcc
     3361 aagacttgat aaactcctcc ttggctgttg gctggtgcta gagcagtcgc cacagctttg
     3421 gctttctcat cagcattttc catcgcatag gcaattccag ccatttcaag catttcaaca
     3481 tcattttcac tatcaccaaa agccatgatt tcttgggatt tcaagtccca gcgcttgagt
     3541 aattcctcca agccccatgc tttatgaatc ccagcttgga tgatatcaat gcaaccatag
     3601 ccactggata cagctcggac acggccatca aagagagcat tgatttcttc caaaaccgaa
     3661 ctcaaacgtt cctcaccaac aaccatgctc atcttgagca caccaccaaa gaggtcagat
     3721 gttaattcat ccacaaattg catccgttgg tagaattttt caatcatttc tggagtcata
     3781 aaactttcaa gatctgtaaa aatcgtacct tccttgacaa aatcaccctt catccccgtt
     3841 acaacaaact ggtcctgaca cgctcgaacc ttgaaatgag tcaaagcctt gttgacaatg
     3901 gcgtcatccc atgtctgagc ctgaatcaat tcattgtttt caaaaatacg agcgccatta
     3961 gcaacaacca gaaccactcg atccaccaag ggactcagta gttgtctcat gcggtgaatt
     4021 tcattgcccg tcgcaatgac aaaacgaatg cccctttgat ccaactgatc taaaatcttt
     4081 tccaatcgtg ggagatcaag ctgacctcta gcatccagca aggtcccatc catatctgtc
     4141 gcaattacct taatcatcat ttactttcct ctggattcaa gctaatacca cttcaatccc
     4201 acatgttcat tcatttcttt ataggctgta tcaattcgtt ccttagtcgc ttcatctaac
     4261 tggtcacgat gactgccatc ctctataaaa tcttccaaaa tataagtttg gtaatgatac
     4321 aagggatatc cttctggtga aaaggttccc tttggtgttc gattgaccca agtaggatga
     4381 gctttagctg ttccgatagt tgtttttcca tccttcttct tgatggtgac atccatgaga
     4441 acaccacgtt cagtccactt agcattctct tcatctccca tagattcaat tcgttgattg
     4501 gaaatgaagt tccccattta atagacaatg agcttcttat ctccatcttt ttcaatcgtt
     4561 tcagatggtt caacaacgta aagatgccct ccaaagataa tatccgctcc ccaatcgatc
     4621 atcttgtgat aaagagcttt ttgttcttca gttggttcca atcgatactc aacacccatc
     4681 tgaggcatga taatggtgat atctgcttcc ttctctgccc gttcaatttc agccttcatc
     4741 ttatcttcgt ttaaatctga aagataacga ttatagtctt cctgagaaat atactgctca
     4801 attccattga aaccatagga ataggctaac aatgcaacct tgataccatt cacttcctta
     4861 atgaccagcg gagcctgatc acgtggttcg tgcgtataaa ctccgattgg agtgattcca
     4921 gctttctcaa taatatcggc cgttgaaata actccctcaa tttgcgaatc caaaatatga
     4981 ttatgagcta aatccagcac atgataacct gcctccttaa tagcatccat aacttcagca
     5041 ggagcattaa agagaggata acccgctaaa taatgatcct tattaatggt ttcttcaaaa
     5101 tcaccaatag ctaaatctgc ttgcttgaac caaggagtca catactcaaa attttcatga
     5161 aagtcatagg taccgtcttc ttttttagct gaaaagaaaa gtccatcgtg gtagagcaaa
     5221 tccccgtggg ccataattct ggcagttttt tcctcttcct actcctgaga cttttgctta
     5281 gttccctctt gagaaatagt atctcgtttt tgactagtca agagattcct tggaagcttt
     5341 caaacaataa gaccaagccc attgataaac caactgctag caagagtatc gccacaaatc
     5401 ccttattgct ccacttgcga taactcctaa aaagtttacc aagcccttca taaaacgaaa
     5461 agctaaacca ccctgatttc gattttgtct tctttgcatc ttcattctcc ctactttctt
     5521 atgcaagcct tttcttttta ttatatcaca gataagtatt tctttcacaa ttgaattgaa
     5581 cttcccatct attttctata aatcctaaat gccataatgc tttcaattct tgtcattttg
     5641 tgatatcatg tagaggtaat gaaaggaaat gaactaatcc acagtggctt attccaagta
     5701 taccacttgg gctttggcag tagttaactg cactaaacat aatataagga gagaaaatgt
     5761 ctgcaataga acgtattaca aaagctgctc acttaattga tatgaacgat attatccgtg
     5821 aagggaatcc tactctacgc gcgattgctg aggaagtcac tttcccccta tctgaccagg
     5881 aaatcatcct aggcgaaaag atgatgcaat tccttaaaca ttcccaagat cctgtcatgg
     5941 ctgaaaaaat gggactccgc ggtggtgttg gactggctgc tccccagtta gatatctcaa
     6001 aacgcattat cgctgttttg gtacctaata ttgttgaaga aggcgaaact ccacaggaag
     6061 cctacgattt ggaaggcatt atgtacaatc caaaaatcgt ctctcactct gttcaagatg
     6121 ctgctcttgg cgaaggagaa ggttgcctgt ctgttgaccg taacgtgcct ggctatgttg
     6181 ttcgccatgc ccgcgttact gttgactact ttgacaaaga tggagaaaaa caccgtatca
     6241 aactcaaagg ctacaactcc attgttgttc agcatgaaat tgaccacatt aacggtatca
     6301 tgttttacga tcgcatcaat gaaaaagacc catttgcagt taaagatggt ttactgattc
     6361 ttgaataaag aaaatcccgt tgcaagacgg ggttttgtgt tataatagag gcatgaaaac
     6421 aaatgatatt gtctatggtg tccacgccgt taccgaagcc ctccttgcaa atacaggaaa
     6481 caaactctac ctccaagaag atctccgagg taagaatgtt gagaaagtca aggaactagc
     6541 tacagaaaag aaggtgtcca tttcttggac atcaaaaaaa aatctctctg agatgactga
     6601 aggtgctgtt catcaaggtt ttgttctacg agtgtctgaa tttgcctata gcgagctaga
     6661 ttacatcctt gcaaaaacac gccaagaaga aaattcactt ctattgattc tagatggtct
     6721 aaccgatccc cataatctgg gttctatctt gcgaacagcc gatgcgacca atgtttcagg
     6781 tgtcatcatt cccaagcacc gtgctgtcgg agtaactcct gtcgttgcca aaacagccac
     6841 aggtgctatt gaacacgttc caattgcccg agtaaccaac ctcagtcaaa ccttagataa
     6901 actcaaggat gaaggtttct ggacctttgg aacggatatg aacggtactc cttgccacaa
     6961 gtggaataca aaagggaaaa tcgccctcat cattggaaat gaaggaaaag gtatctctag
     7021 caacataaaa aaacaggtcg atgaaatgat taccattccg atgaatggac atgttcaaag
     7081 ccttaatgcc agtgttgctg cggccattct catgtacgaa gttttccgaa atagactata
     7141 aaaaagtttc cagtcatctg attggaaact tttttatgat taactatgtt ctgtaatgaa
     7201 tttataggct tcttgaccag cgatagctcc atctccaact gctgttgtta cttggcgaag
     7261 gtctttcaag cgaacatctc caactgcaaa gataccgtcg actgcagtct tcatgtggct
     7321 atctgtcaca atccagcctg cctgatcttg gatattcaat tctttaacaa aatcgctaag
     7381 agggtccaaa ccaacataga taaagacacc accgaaggct tgctctgtca cttgacctgt
     7441 tttcacattt tcaaaaacga cagattctac tctgttttca cccttgattt tccttactac
     7501 agaatcccat ataaagctga ttttctcatt ggcaaaggcg cgatcttgta aaaccttttg
     7561 ggcacgaagt tggtcacgac ggtgaacaat ggtaacagtc ttagcaaaac gagtcaagaa
     7621 gagggcttct tcaacagctg aatctccacc accaactacc aataaatctt ggtcacggaa
     7681 gaaagcacca tcacacacag cacagtaaga aacaccacga ctgttcagtt cttcttctcc
     7741 aggcactccc aaaggacggt gtttagaacc agttgctacg ataactgtac gtgtttcata
     7801 tgtttggtca tcagtcatca ctttcttaaa atcaccatgg tcttcgacat tttcaacata
     7861 accataaatg tgctcaacac caagattttc aagtggttca aacatctttt cagccaattc
     7921 aggtccacta atattagcgt atcctgggta attttcgata tcagatgtat tattcatctg
     7981 accacctggc agaccacctt caatcaaagc tacttttaga ttgcttcgag cagcatacaa
     8041 ggccgcagtc atccctgcag gtccagcacc gataataata gtatcgtaca tatagattcc
     8101 ttctttcttg ttgtaactat ctttattcta actctttctt gtcaatcacg caaggattat
     8161 gccttgaaaa caagaattaa actcataacc gcaaaggata atactgggac aaccaagact
     8221 ccaatcataa tcatatcata gagatgggct tggcgagcct tggctgtctt atcaactccc
     8281 gacatggctc tcagaccaat ccaaatccct aaaaaaatca gaacaaggat ggtggtcaag
     8341 atcaaactct cgaaatataa agaaaatagt tgcagtagca tgatttctct catttctatc
     8401 ttttttaaag agtaaactca gctagtccaa ctaactgagt tttcctttat ctattatatc
     8461 aaatataagt ccgtttgtaa ctagcgaaga attcttttgt ccgctcttct ttaggggtgt
     8521 ggataatctc atccggagtt ccagactcga tgattttccc cttatctaag aagagaatct
     8581 tatccgcaac ttgggctaca aaggacatgt catgactgac caaaatcatg gtctgacctg
     8641 acttagcagc atctgcaata gacttttcta cttcaccgac caattctggg tcaagggctg
     8701 aagttggttc gtctaagagc aaaacatctg gtttcatagc aagcgcacgc gctagggcaa
     8761 cccgttgctt ctgtccacct gataaatggc gaggataatg gttttcacgg tccgaaagcc
     8821 caaccttagc caactcttcc ttggcaatct tagtcgcttc ttggtcagat aatttcttga
     8881 caacaaccaa gccttctttc acattatcaa gtgctgttcg gcgttcaaac aaattaaact
     8941 gttggaaaac catagacaac ttacggcgta gggcaaggat ttcttcttga gtgattttag
     9001 aaaaatcaac tgaaaaacca tcaatctgaa tagagccact gtcaggtgtt tcaagataat
     9061 tgagactgcg aagaaaggtt gattttccag ctcctgaaga accaatcaag gctacaactt
     9121 cccctttttg aatatccaag tccagatgat ccaagacaat ctgtcctgaa aaggatttgc
     9181 ttaaattcga aatcttaatc attaacgaag gtctcctttc acatctgttt gcactgtatc
     9241 aggtgcagaa atagccattt ttctctcgat gaaacgaccg agactttcaa ttccgatatt
     9301 gactacccaa taaacaaggg caacggagat gaagcgttca aaatagcgat aatcagctcc
     9361 acctagaatc tgagcttggg caaagacttc cacaacaccc gcactaaaag ctagagatgt
     9421 tcccttggtc aaaccgatga gggaattaat caaggttgga gtagctacca ccgctgcatt
     9481 aggaataatc actcgtcgat aaacttgcgc tcgggtcata cccagactgc gtgccgcctc
     9541 aatctcacca ggattaactg agagaatggc tgcacgaatg gtttcactag cataagctgc
     9601 ctcattaaag gcaaaggcga caatcgcaaa agctgcagct ggaatcgcat tgatattgag
     9661 accagttccc cattgctgat tgagggcttt caaagccaaa gggattccgt agtaggtcaa
     9721 catgagttgc accaaaatcg gtgtcccttt taagaaacta acaaagaagg cctgcaaggg
     9781 atataaaatc ttgacacgat tgatcttcac aatggcaaaa agaagcgcca aaaccaagcc
     9841 aaaaagggca ccaccaattg tcaacataat tgttgttgga agttgttgga caattctagg
     9901 gattccatca aagaccgaac gtaggctaaa cagcttgcca ttcggaatca attgcatcaa
     9961 gttttggtac caatctgatg ctaaaatcgt tgtaacattc ataaaaacat cctcttctga
    10021 taatgattca ttctaccatg cttctgccgt caatgaaatt atttgctacg gtcagataca
    10081 gactttgtct acctactagt ttatcatact ttgaaacagg gaagttatat attttatcta
    10141 tcaaagagat agataaaaac tatttcagtc ccagttcttc ataagatttt cgataaccga
    10201 tttgcttaac ggttccattt tctactaaaa tgggccgttt taacaacata ccgtcacttg
    10261 ctagcaactc agccgcttct tggtttgaca aacttcctac cttatctttt agccctaatt
    10321 cacggtattt gataccactg gtgttgaaaa attgcttcaa ttcaaatcct gaggtttcta
    10381 gccaattcaa aatgacttct tggctaggtg tttcttccac gatatggacg gctttatagt
    10441 ccacacctaa ttgatttaat tcttgttttg cttttttaca agttgaacat ttggggtatt
    10501 cgataaattc taacatgtgc ttctccttct attgcttcta tctttaaaat ctactccttc
    10561 atgctccaag agccaagctt tcttttccac tcctgcagca taacctgtca gacgcttgcc
    10621 tgctcccaac acacgatgac aaggtactag gatagaccaa ggattgcgtc ccactgctcc
    10681 accaattgct tgagcagaag ccacttgcag gtcttgagca atttgtccat aggtcactgt
    10741 ctgaccataa ggaatgccct gtaaatagtc ccaaactctc ttttcaaaat tcgttccgat
    10801 tggcgccaag agcaagttgg ataaatcctg aggcttgcct ttaaagtaat catctaagca
    10861 agcaataact gggtctaaaa taggatgact aacaacttct tctatcgttt catctcctag
    10921 tcccctctca aaatgcttct gctcctgaac ccaaattcca tacaaataat ggtcatcagc
    10981 tacaagtgat agaataccaa ttggtgagga gtagagtatt tttacatact tcttttgcat
    11041 tatttcttta atttttgata ggccaagcgt tcgccatcta ctggcacctt accaacttgt
    11101 ttaaaaccaa gtttttcaaa aatatgttgc ataaccttgt tttcagcatg cgtatctgag
    11161 cgaaaatcaa gataatcaaa accttcaatc aagccctcta agaaggtttg agcaactcct
    11221 tttccctgca catctgctgc cacagcaata cggtgaaaga ctagatactc tgactctcca
    11281 gcttgccagt ttccctcata aatagcttca taggcctcct ctggactctt ggtcacagca
    11341 gcataggcta gcagttctcc ctcttccaag gctacgtagg cttgccctga gatgatatca
    11401 tcgataataa catctgcatt tggatagcca ttttgccact ggtcactacc agcatctgct
    11461 aaacattttt tggcatcctc catcacctgc atgatggcat ctacttcatt tggaaaagct
    11521 aaacgaattt ccatcttttt tcctcatttc tgactagttt ctcccatcat agcataattt
    11581 aagtatttct acaagcagtt aaaacttgac tttgtgtttt tgttatttta taatctagtt
    11641 atcaaaacta tataaaaagg agttgaaaat gaaaactacc ttttcctacc caaaatgggc
    11701 agaaattcca aacattgacc tctatctgga ccaggttttg ctctatgtca atcaggtctg
    11761 cgcccctatc tctcctaata aagacaaggg cctaacagca tctatggtca acaattatgt
    11821 gaaaaatggt tacctgacaa agcctgacaa aaaaaaatac caacgccaac agattgcccg
    11881 tttgattgct atcacaaccc tcaagtctgt attttctatt caagaaatag cccagacact
    11941 taatactcta caaactcaag caagttcaga ccaactctac gatgcttttg tggactacat
    12001 gaaccaagga attgacccag ctaaccctat tatccaaacc agctgccaaa ccgttaaact
    12061 ctatcatcaa actctagact taatcgatca tactcaagag gaggtaatcc aatgaacact
    12121 agtcttaaac tcagcaaaca actcagtttt ggagaggaga ttgctaatag cgtgacccat
    12181 gctgtgggtg cagtcatcat gcttatcttg ctgcctattt catccatcta tagttatgaa
    12241 gcacacggat ttttatcctc tatcggcgtt tccattttcg tcatcagtct ctttctcatg
    12301 ttcctatcat ccaccattta tcactctatg gcctatggtt cgacccacaa atatgttttg
    12361 cgaatcattg accattctat gatttacgtt gccattgccg gctcatacac gcccgttgtc
    12421 ttgaccttga tgaataactg gtttggctat ctgattattg tcatccaatg gggaacgacc
    12481 atctttggta ttctctataa aatctttgct aaaaaggtca atgagaaatt tagccttgct
    12541 ctttacctga ttatgggctg gttggttctg gctatcattc ctgccattat cagtcaaacg
    12601 acacccgttt tctggagtct catggtaact ggcggactct gttatacagt tggagctgga
    12661 ttttatgcca agaaaaaacc ttatttccac atgatttggc atctctttat cctaactgcg
    12721 tccgtacttc aatacatcgc tattgtttat tacatgtaaa actctcagta ggcagagcct
    12781 gcttagagtt ttacaaacga atttcccaaa gaggaagcaa tatgaaagca gtcattgctt
    12841 gtgttcataa aattctcaga atcatttaca aactactctc caccaagtag acttatcaaa
    12901 aagaaaaggc gctaggactg aagaaacagt tctaacgccc aaattaaaaa aatttcaact
    12961 acagtatagc acaggaaatg attttttgcg cttttttact gttttttcaa ataaaaaaag
    13021 acaaagtttt atccttgtct tttagtttta gtattgcttt ggtttcaatg tcaataagtg
    13081 tgtt
//
LOCUS       DAYYYC010000055        12867 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.055, whole genome shotgun sequence.
ACCESSION   DAYYYC010000055 DAYYYC010000000
VERSION     DAYYYC010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12867
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.055"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..139
                     /locus_tag="ACHBV5_001768"
     CDS             <1..139
                     /locus_tag="ACHBV5_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="choline-binding protein D"
                     /protein_id="HFM9967525.1"
                     /translation="EASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNANGEW
                     V"
     gene            539..1660
                     /gene="mnmA"
                     /locus_tag="ACHBV5_001769"
     CDS             539..1660
                     /gene="mnmA"
                     /locus_tag="ACHBV5_001769"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFM9967526.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLATAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTNLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1801..2256
                     /locus_tag="ACHBV5_001770"
     CDS             1801..2256
                     /locus_tag="ACHBV5_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFM9967527.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNEKTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2266..4179
                     /gene="mnmG"
                     /locus_tag="ACHBV5_001771"
     CDS             2266..4179
                     /gene="mnmG"
                     /locus_tag="ACHBV5_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFM9967528.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4513..6192)
                     /locus_tag="ACHBV5_001772"
     CDS             complement(4513..6192)
                     /locus_tag="ACHBV5_001772"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFM9967529.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6194..6427)
                     /locus_tag="ACHBV5_001773"
     CDS             complement(6194..6427)
                     /locus_tag="ACHBV5_001773"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HFM9967530.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6707..6922
                     /locus_tag="ACHBV5_001774"
     CDS             6707..6922
                     /locus_tag="ACHBV5_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967531.1"
                     /translation="MYNLFAFAIGVRLLAFIVFVACVYGGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            complement(7245..7397)
                     /gene="cibB"
                     /locus_tag="ACHBV5_001775"
     CDS             complement(7245..7397)
                     /gene="cibB"
                     /locus_tag="ACHBV5_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HFM9967532.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7399..7584)
                     /gene="cibA"
                     /locus_tag="ACHBV5_001776"
     CDS             complement(7399..7584)
                     /gene="cibA"
                     /locus_tag="ACHBV5_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HFM9967533.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7762..8445
                     /gene="tsaB"
                     /locus_tag="ACHBV5_001777"
     CDS             7762..8445
                     /gene="tsaB"
                     /locus_tag="ACHBV5_001777"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFM9967534.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8442..8879
                     /gene="rimI"
                     /locus_tag="ACHBV5_001778"
     CDS             8442..8879
                     /gene="rimI"
                     /locus_tag="ACHBV5_001778"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFM9967535.1"
                     /translation="MIEIKRIQQHPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8869..9879
                     /gene="tsaD"
                     /locus_tag="ACHBV5_001779"
     CDS             8869..9879
                     /gene="tsaD"
                     /locus_tag="ACHBV5_001779"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFM9967536.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHELPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFANLDLNAKPSLAFDT
                     ME"
     gene            complement(9919..11225)
                     /locus_tag="ACHBV5_001780"
                     /pseudo
     CDS             complement(9919..11225)
                     /locus_tag="ACHBV5_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11561..12218)
                     /locus_tag="ACHBV5_001781"
                     /pseudo
     CDS             complement(11561..12218)
                     /locus_tag="ACHBV5_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12461..>12867
                     /locus_tag="ACHBV5_001782"
     CDS             12461..>12867
                     /locus_tag="ACHBV5_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HFM9967537.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKT"
BASE COUNT         3689 a         2519 c         2989 g         3670 t
ORIGIN      
        1 tgaagcatca ggtgctatga aagcaagcca atggttcaaa gtatcagata aatggtacta
       61 tgtcaatggt ttaggtgccc ttgcagtcaa cacaactgta gatggctata aagtcaatgc
      121 caatggtgaa tgggtttaag ccgattaaat taaatcatgt taagaacatt tgacatttta
      181 attttgaaac aaagataagg ttcgattgaa tagatttatg ttcgtattct ttaggtacct
      241 atcttatgat ttcaggaagt gtcattaaaa aaacgactcc ttttctctaa cttgaaaaat
      301 agattagaga aaatgggttg ttttatttat tatagttatt tgaatgaaga taagaagagg
      361 gtatactcac gtcattcaca tgatctgtat attgactata agttttaaaa aacaattttt
      421 aagctcttcc ttgtcttctc taaccaagcg tgttataatg aatactgctc aagcgacctt
      481 caatcgtgaa gcacacacga ccttcaatcg tgaataaacg aatagatgga gacttaccat
      541 gagtgataac tctaaaacac gtgttgtcgt ggggatgagt ggtggtgttg attcgtcggt
      601 gacggctctt ttgctcaagg agcagggcta cgatgtgatc ggtatcttca tgaagaactg
      661 ggatgacaca gatgaaaacg gcgtttgtac ggcgaccgaa gattacaagg atgtggttgc
      721 ggtggcagac cagattggca ttccctacta ctctgtcaat tttgaaaaag agtactggga
      781 ccgcgttttt gagtatttcc tagcggaata ccgtgcaggg cgcacgccaa atccggacgt
      841 tatgtgcaac aaggaaatca agttcaaggc ctttttggac tatgccatga ccttgggggc
      901 agactatgta gcgactgggc attatgctcg agtggcgcgt gatgaggacg gcactgttca
      961 catgcttcgt ggcgtggaca atggcaagga ccagacctat ttcctcagcc aactttcgca
     1021 agaacaactc caaaaaacca tgttcccttt gggacatttg gaaaagcctg aagtacgcag
     1081 actagcagaa gaagcaggcc tggcgactgc taagaagaaa gattcgacag ggatttgttt
     1141 tatcggagaa aagaacttta aaaacttcct cagcaactac ctgccagctc agcctggtcg
     1201 catgatgact gtggatggtc gcgatatggg cgagcatgca ggtcttatgt actatacaat
     1261 cggtcagcgt ggcggactcg gtatcggtgg gcaacacggc ggtgacaatg ccccttggtt
     1321 cgttgtcgga aaagatctaa gcaagaatat tctctatgta ggacaaggat tctaccatga
     1381 ttcgctcatg tcaactaacc tagaagccag tcaagtccac tttactcgtg aaatgccaga
     1441 agagtttacg ctagaatgta cggctaaatt ccgttaccgt cagcctgact ctaaggtgac
     1501 cgtccatgtc aaaggagaca aggcagaagt tatctttgcg gaaccacaac gcgcgattac
     1561 accaggacag gcagttgtct tttacgatgg cgaagagtgt ctaggtggcg gtttgattga
     1621 caatgcttac cgcgatggac aagtttgtca gtacatttag attgacaaat tttctcaatt
     1681 tgctacaata ataacagcaa tagaaatgat ggtcaaagct catggatgtt gcaggctttt
     1741 ttgtcctgca cttctttgta gttttgactg tttttgtgtc gtttaaggga aaggacaaga
     1801 atgactcaac aagactttcg gacaaaagta gacaatacgg tttttggtgt tcgggcgaca
     1861 gccttgattg tccaaaatca caagcttcta gtcaccaaag acaagggcaa gtattacact
     1921 atcggcggtg cgattcaagt taacgaaaaa acggaagacg cggtagtccg tgaagtgaag
     1981 gaagaactag gtgttaaagc tcaagctggg cagctagctt ttgtggttga aaatcgtttt
     2041 gaagtggacg gcgtttccta tcacaatatc gagtttcatt atctggtgga tttgcttgaa
     2101 gatgccccgt tgaccatgca ggaagatgag aaaaggcagc cctgtgagtg gattgacttg
     2161 gataagcttg aggatatcca gctagttcca gcctttttaa aaacagccct accagattgg
     2221 gaaggccaac taagacacat tcatcttgag gaataggaga gaaacatgac ttatcatttt
     2281 actgaagaat acgatattat tgtaattggt gcgggacacg ctggggttga ggcttccttg
     2341 gccgctagcc gtatgggctg taaggtcctg cttgcgacca tcaatattga aatgctggct
     2401 ttcatgcctt gtaatccctc tatcggtggt tctgccaagg ggattgtcgt gcgtgaagtc
     2461 gatgccctcg gtggcgagat ggccaaaacc attgacaaga cttacatcca gatgaagatg
     2521 ctcaacacag ggaaggggcc agctgtccgt gcccttcgtg cgcaggctga caaggaactt
     2581 tactctaagg agatgcgcaa gacggttgaa aaccaagaaa atctgaccct tcgtcaaacc
     2641 atgattgatg agattttggt ggaagatggc aaggttgtcg gtgtgcgtac agccacccat
     2701 caagaatatg ctgctaaggc tgttattgtg acgacaggga ctgctctccg tggggaaatt
     2761 atcatcggag acctcaagta ctcatcaggt cctaaccaca gcttggcttc tattaaccta
     2821 gctgacaatc tcaaggaact gggcctcgaa atcggtcgtt tcaagacagg aacccctcca
     2881 cgtgtcaagg cttcttctat caattacgat gtgacagaaa tccaaccagg agatgaagca
     2941 cctaatcact tctcatacac ttcacgtgat gaggattatg tcaaggacca agtgccatgc
     3001 tggttgacct acaccaatgg taccagtcat gagattatcc aaaacaacct ccaccgtgcg
     3061 cctatgttta caggtgtggt caagggagtg gggcctcgtt actgtccatc gattgaggac
     3121 aagattgtgc gctttgcgga caaggaacgt caccaactct tccttgagcc agaagggcgc
     3181 aatactgagg aagtctatgt tcaaggactt tcaaccagtc tgcctgagga tgtccagcgt
     3241 gacttggttc attccatcaa aggtttggaa aatgcagaga tgatgcggac aggttatgct
     3301 attgagtatg atatggtctt gcctcatcag ttgcgtgcga ctctggaaac caagaaaatc
     3361 tcaggtctct tcactgctgg tcagacaaat ggaacatcag gttatgaaga agctgctggc
     3421 caagggatta tcgcgggtat caatgcggct ctgaaaatcc aaggcaagcc tgagttgatt
     3481 ttgaagcgca gtgacggtta tatcggggtg atgatcgacg acttggtgac caagggaacc
     3541 attgaaccct accgtctctt gacaagtcgt gctgaatacc gtctcattct tcgtcatgac
     3601 aatgctgata tgcgcttgac tgagatggga cgcgagattg gccttgtgga tgatgaacgc
     3661 tgggctcgtt ttgaaatcaa gaaaaatcaa tttgataatg agatgaaacg cctagacagt
     3721 atcaaactca agccagtcaa ggaaaccaat gctaaggttg aggaaatggg cttcaagccg
     3781 ttgacagatg cggtgacagc caaagaattc cttcgccgtc cagaagtttc ttaccaagat
     3841 gtggtggcct tcatcggacc agctgcagaa gacttggatg acaagattat cgaattgatt
     3901 gaaacagaaa tcaagtacga aggctatatt tccaaagcca tggatcaggt tgccaagatg
     3961 aaacgtatgg aagaaaaacg cattccagcc aatatcgact gggatgacat cgattctatt
     4021 gcgacggaag ctcgtcagaa gttcaaactc atcaatccag aaaccatcgg ccaagccagc
     4081 cgtatttcgg gagtaaaccc agcagatatt tctattttga tggtgtatct ggaaggtaaa
     4141 aatcgtagta tttctaaaac tcttcaaaaa tcaaaatgat acgtcgtcgg cttcttacga
     4201 atgagttcaa agcttggctt tgattcatct ccaacctccc atagttcccc gaactatggg
     4261 agctaactca agttatgctt tcgcttagcc ttctagtctg attttcattg agttttaatc
     4321 tcaaaagaaa gcatagagaa aaacagctcc gaagacgggg ctgttttgtt gatttgtact
     4381 caatgaaaat caaagagcaa actaggaagc tagccgtagg ttgctcaaag cactgctttg
     4441 aggttgtgga tagaactgac gaagtcagta acatatatac ggcaaggcga agctgacgtg
     4501 gtttgaagag tattattctt catctggtgt gaggatcatc gggatgatga tcggttcacg
     4561 ttcggtattt tcatagagga aggggcgaat agcgttgaca atggcaccat tgacagattg
     4621 cacgctagca tccttatttt tcagtgcgat acgaatggca ttgaagagga tacgctggct
     4681 ttggcgaatc aagtcgccag actctctcat gtagacaaag cctcggctga ggatgtctgg
     4741 accagataga atcatctgcg atttgaagtc aacagttgcg actgccagaa cgacaccgtc
     4801 ttcagataga tcgcgacgat ctttgaggac agctgcgcca atttcaccga tacgatttcc
     4861 atcgacatag atatcttggg cgttgaaatg acctgcgata cgagctgagt cagcagtaag
     4921 ggcaagcaca tcgccattgc tcatgataaa gatattgtcc ttctcaacac cagtatccac
     4981 tgctagtcca gcgtggactt tttgcatgcg gtattcaccg tggacaggca tgaagtattt
     5041 tggcttaatc aagcagagca tgagtttttg ctcttgctga ccaccgtgtc cagatgtatg
     5101 gatattgttt actttaccgt ggataacttc gacaccagct tcagaaatga tgttaatcag
     5161 cttgttgacg ctagtagtgt ttccagggat gggactagaa gagaagataa cggtatcacc
     5221 tggttgtaat tgtacttgac ggtgggttcc gttggcgata cgagagaggg ctgccatagg
     5281 ctcaccctga ctacctgtac agaggataag aacttctcct gcaggataat ctttgatttc
     5341 atttggctcg ataaaggttc ccttaggagc tttgatgtag ccaagatcga ttccgttgac
     5401 aatggccttt tccatagaac gaccaaagac cgcaatcttg cgtccagtct taacagcagc
     5461 ttctgttgcc tgctggagac ggaagatatt tgaggcaaag gatgcaaaga tgatacgtcc
     5521 ttcaatacct tggataatct tcataatgga ctgaccaacg actttttcag agttggtaaa
     5581 ggttggtact tccgcatttg tcgagtcaga caggagacag agcacgcctt cttcaccaag
     5641 cgcagccata cgatgcaagt ccgcaggttc tccaactgga gtaaagtcga acttaaagtc
     5701 acccgtacag acgattttcc cttgaggagt atgaatgaca atccccaaag gctctggaat
     5761 agagtgagtc gttctaaaga aagttgcctt gagattttta aaggtcaact cggtgttgtg
     5821 gttgatttcg taaagtttgg cgttgcgcaa gaggccgtgt tcttcgagtt tcccacggat
     5881 caaagccaag gcaagcggtc cagcgtagat agggacattt gcttgcttga gtaggaacgg
     5941 aatcccacca atgtggtcct cgtgtccgtg tgtgattaaa acagccttga cgcggtcgat
     6001 attgtccacg atgtaagagt agtcaggaat gacatagtcg ataccaagca agtcatcttc
     6061 tgggaattta atcccagcat cgacgatgat aatctcgtct tggtattcaa ttccgtaagt
     6121 gtttttcccg atttctccta gaccaccgat ggcaaaaacg ccgacttctt caggtttaag
     6181 agtgtaggcc atattagaac tccgtaattt cgaaggcgcc agtttctttt tcgtaatcga
     6241 gcaatttgtc agacaagagt tcgatatatt cgatattgta ctctgggcga ttttcttcga
     6301 caagttggcg agcagtgata cggccctcaa gttctgagct ggcatcgatg tctaggtaaa
     6361 gcgcgcgtgt tgtttcacgg cgtgggctac gttcttttgt ttcttgataa aaaactttgt
     6421 aaatcatata gttcctttct atttacaggt cagcttattc caaactttta gcagagattt
     6481 gcttgatttc attccatttt gtgtctagat tgaccttgat tcgttacaat tatttcaatt
     6541 ataccacaaa atgaaaaatt agtaaaagac ggaaacgaga aagttagggg acgatttctt
     6601 tggtaagcgt ttgcaaaaat aaagaaaatg tattatgttg ataacggaag tgaaatttat
     6661 tgcttgtcat aattccatat agattttaag tcaaggaggt tgccctatgt ataacttatt
     6721 tgcttttgct atcggagttc gtttgctagc ttttatcgtt tttgttgctt gcgtttatgg
     6781 aggaaatctt ctatttgcca aactggaacg acgacaaacc aagttcttgt ggaaaatgac
     6841 ctttgtgact ctctactcgc tttttctcct cctcgtgacc tatgtcgttt ggtttgtatt
     6901 ttactttgaa ttaaatgctt agatgccctg cttatgctgg ggttttttgt ttggggatgt
     6961 agagatagta gatttacgac acgaaaattc caccccatct atcaagatga ggtggtcttt
     7021 gcatttttct aacatgacat gacaatggaa ttttcaaagc ttattatttt tatgggagtc
     7081 attgttctga tcaaaaatag agttgaagca taaaaataaa acaatacaaa cagataaatc
     7141 gaatggtaaa gggatggtag taatgttcaa atcattgaga atgctgagca aactgtaaga
     7201 gatgaagaca ataaaattta tccttctaaa aatgtgtttc ttatctagca tgacttacca
     7261 aactttttac gaaggtcttt tccaatggta taacctgcca taaataaagc gataccaaca
     7321 ccgacaccaa agccaccctt gatttcttgc aattccttat tagaaatttc acgataattg
     7381 ttcaaatctt tcatcatatt aatctcctcc taaaaaataa ccagctgcca aaccagaacc
     7441 tataagtgct gttccacctg caatagcctt ccaagatact gctactccaa agataaccaa
     7501 gggagcgaga ccgccatcaa tatctgataa ttcattttca gataaggata aaaattgatt
     7561 gtcaagaatg tcaaaatttg tcattgaact ttcctccttt tttcttgttc acttttatat
     7621 tcggaaaaga aaaggaaaag tgagcatttt tttaaattat ttttagttaa gtgagggcac
     7681 tcttgtctgg gggcaaagaa aattcccatg tgccagcttt tgtagtataa tagtaagcag
     7741 acaaaaagat aggaatgtgt tatgaaagta ttagcttttg atacgtccag caaggctctt
     7801 tctctggcta ttttagagga taagcaggtt cttgccgaga cgacgattaa tattaagaaa
     7861 aatcacagta ttactcttat gcctgccatc gattttttga tggcaagttt ggattggaca
     7921 cccaaggatt tggaccgaat cgtggtagct gaagggccgg gtagctatac aggcttgcga
     7981 attgcggtag caactgctaa gaccttagct tacaccctga acatcgagtt ggttggtatg
     8041 tcgagtctct tggctctggt gccccaccaa caagaaggtt tgtttgtccc cttgatggat
     8101 gcgcgtcgca ataatgttta tgcaggattt tatgaaaatg ccaaacctgt catggcagaa
     8161 gcgcacctat cttttgaaga ggtgctagaa aaagtcaagg gtactagtca ggtaaccttt
     8221 gtcggagaag ttggcccctt tgttgagcag attcaaaaac acttgccaag gactgattac
     8281 aaagaaacat tgcccaatgc agccaatctt gctcttttag cttgggacaa ggaagcagac
     8341 tccttgcatg attttgtgcc gaactacctc aagcgtgtcg aagctgagga aaactggctc
     8401 aagaatcaca ccgagtctgg tgagtcctac attaaacgcc tatgatagaa atcaagcgaa
     8461 ttcaacaaca tcctgaccta gctcaagcca tctacgctgt tatggcagct gtttacctag
     8521 tcagtccttg gactctggag caaatccaag cagatctgtc ccaagaccag acttggtatg
     8581 cattggctta tgatggggca gaagtgattg gatttctagc tgtgcaggag aatctttttg
     8641 aagcagaagt cctgcaaatc gctgtcaaag gagcttatca gggtcaggga attgcgtcag
     8701 ccttgtttgc tcaattgccg acagacaagg aaattttcct cgaagtcaga cagtcaaatc
     8761 aacgagcgca agcattttac aagaaagaaa agatggcagt tatcgctgag cgaaaggcct
     8821 actaccatga cccagtcgag gacgccatta tcatgaagag agaaatagat gaaggataga
     8881 tatattttag catttgagac atcctgtgat gagaccagtg tcgccgtctt gaaaaacgac
     8941 gatgagctct tgtccaatgt cattgctagt caaattgaga gtcacaaacg ttttggtggc
     9001 gtagtgcccg aagtagccag tcgtcaccat gtcgaggtca ttacagcctg tatcgaggag
     9061 gcattggcag aagcagggat taccgaagag gacgtgacag ctgttgcggt tacctacgga
     9121 ccaggcttgg tcggagcctt gctagttggt ttgtcagctg ccaaggcctt tgcttgggct
     9181 cacgaacttc cactgattcc tgttaatcac atggctgggc acctcatggc agctcagagt
     9241 gtggagcctt tggagtttcc cttgctagcc cttttagtca gtggtgggca cacagagttg
     9301 gtctatgttt ctgaggctgg cgattacaag attgttgggg agacacgaga cgatgcagtt
     9361 ggggaggctt atgacaaggt cggtcgtgtc atgggcttga cctatcctgc aggtcgtgag
     9421 attgacgagc tggctcatca ggggcaggat atttatgatt tcccccgtgc catgattaag
     9481 gaagataatc tggagttctc cttctcaggt ttgaaatctg cctttatcaa tcttcatcac
     9541 aatgccgagc aaaagggaga aagcctgtct acagaagatt tgtgtgcttc cttccaagca
     9601 gcagttatgg acattctcat ggcaaaaacc aagaaggctt tggagaaata tcctgttaaa
     9661 accctagttg tggcaggtgg tgtggcagcc aataaaggtc tcagagaacg cctagcagcc
     9721 gaaatcacag atgtcaaggt tatcatcccc cctctgcgac tctgcggaga caatgcaggt
     9781 atgattgcct atgccagcgt cagcgagtgg aacaaagaaa actttgcaaa cttggacctc
     9841 aatgccaaac caagtcttgc ctttgatacc atggaataaa gagtggctct ttgtcaagtg
     9901 tagtgggtag gcgaaaagct acaatctgga gagtacgaaa ttcgtactct cttttttgat
     9961 gttcaaagtc atcaaaatcc gttttttaaa attgttaaag ttccggaaac caaaggcttt
    10021 gcgcttgata accttaatca aattattggt cgcttcaagt ttagcgttgg aataaggcag
    10081 cttaagtgcg ttgataatct tatctctatc ccttaaaaaa gtccaaaaga ccgtttgaaa
    10141 aagcggatga accgttggca gttcttgctc aatcaatcca aagaaatggt cggcattctt
    10201 ctcttgaaaa tgaaagagca ggagttgata gagttcgtag taaacctgta atccctcaga
    10261 gtaagaaagc agcttatctc gtacttcccg atgggttaag tgcattcgaa acgtgggctg
    10321 atagaatcgt ttctgacaga gcttgaagct atcctggtgt agtaaatcag tccagtggac
    10381 tgatttagcc cgagcctaga aacgaaaaag cgagggttcc aaaagcgctt gagcgcccga
    10441 tactccaagg attttcggtc aaattggttc atgatttgga ttcgtactcg gttcatagct
    10501 cggctcagat gttggacaat gtggaagcgg tcaagaacaa tcttcgcctt tggaaagagt
    10561 tgcttagcga gccgataata agggctgtac atgtccatgg tgatgacctc gaccagctcc
    10621 cgaacctctc tctgatagcg ttggaaatgg tttcgaatca ccgcatgagt tcgcccgtct
    10681 aaaattgcga ggatggattt ggactcaaaa tcttgggcaa tgaagctcat tttgctcttt
    10741 ttgaagctat actcatccca actcataact tttggcaact tggtccaatc ggtttcaaac
    10801 ttaaattccc tcagttttcg gatgacggtg gaagttgaga ccgccaatct gtgggcaatc
    10861 tcagtcatag actgcttttc aaggaggagc tgagcgattt tttgtctcac catgttggaa
    10921 atctggcaat ttttcttgac aatggatgtt tgagaaacga ccaccttaag gcaattcttg
    10981 cactgaaagc ggcgcttttt gagatgcagt accgtgggta aaccctgaca gtcgagaagc
    11041 ggaattttag aggctttctg gaagtcgtat ttgatcatct tcccttgaca atgaggacaa
    11101 ggaggagcgg gggaatccaa ctttgcctga acgactagat gggtttggta tttcagaaca
    11161 gacaagattt tgatattttt gtcttccaat ccgagcaaat ctgtggtatt cttaagttgt
    11221 tccatatgaa ccctttctaa tgagttggtt agacgctttt cattataggt catatggggc
    11281 tttttttcta caagaaacga ccctataatt cctggggtgg gattacccac tacagaaatt
    11341 atagagccaa agcattccaa agtcttgtct gactctggaa tgttttctgt tcacagttgt
    11401 tttgtaactg cctaataagt aaccgcgcta taacgaggta tctaccgaga ttgtcaattc
    11461 tccagtatac tgttataaaa aacaaaactg gaggattttt ttatgtcccc ccatcgtccc
    11521 atcgactgtt ccgtagctgc ccaataacgg agtatagtcg gctgaaacaa gaataggaca
    11581 aaagtgcctc aagaaaagca tcgtaatttg acaatattat tctgagatgt ttttgatgta
    11641 agcccatatt ttctcaatgg gattatactc gggtgaatag gtaggaagtg gtaacagtct
    11701 atgccctgct ccttacacat gttcattctg tgaaaccttg cattgtccat aatgataagg
    11761 gatggtgtat ctaaagtagg tagtaagaat ttttggaagc aagcttcgaa ggagccatag
    11821 tatattgaaa caaaaaaggg cattagtact tctataacag tatcgcaatc tctggtgtgc
    11881 gttgtctcga tcttaattca aataattata tcttcttcca gagagactaa ctgcctgctc
    11941 aaggctcgat catattcgag ataaaaatag gtcttaaccc ctgtctcata aatataaata
    12001 ggagtcaggt agcttaagtg attcaattct ttaaggaacc gatttacttt ttctgggtct
    12061 tgttcgcagt aggtacggct cttttttaga ctatatccca tagcctttag agcgtaatga
    12121 atagttgttg gaggacagtt gaattcagca gctatttcag tcaaataagc atcgggatga
    12181 gtttcaatat agatctttaa tttatctcta tcaacttttt caattaatag tggaagtttt
    12241 cttgaagtta gtgtattgaa acgtttttat acagtgctaa aatttgaagt gtagtgcaga
    12301 tgtatttgta atagtattat agcaattctt tggagaaggt cgagacaaga gaaaataggt
    12361 atctttgaga tataagcatg atttactata aaattattga gttattcata aaaatttctc
    12421 tatcaaatat cataatgcgt cgtttaagga gatggttaca atgcaatata gttgtggaaa
    12481 aataaatatt aatatccctg atggatatgg agacattaag gatatagtgt tttcggctca
    12541 tattatagtt aggtataata atggacattg tggaggtata gatccgcata taattggact
    12601 ttgtaaaaag cagatcagaa ggatgtctct atatcctatt ttgataatcg tatctagaga
    12661 ttcaaaggtt attgatgatt ataaaaattt agatattgcc tatgttgatt gtactcaatg
    12721 ttcaaataat tttgaaactg ccttacacgt taaaaatatt ttaaaattat taaaaatcca
    12781 acttatacac tgtcatggct actcaactaa ttatttttta tatatgttaa aaaaacttga
    12841 caagaatgga tttggaaagg ttaagac
//
LOCUS       DAYYYC010000056        12303 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.056, whole genome shotgun sequence.
ACCESSION   DAYYYC010000056 DAYYYC010000000
VERSION     DAYYYC010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12303
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.056"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(128..640)
                     /locus_tag="ACHBV5_001783"
     CDS             complement(128..640)
                     /locus_tag="ACHBV5_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
                     /protein_id="HFM9967538.1"
                     /translation="MSAQITINHKKARYVRIGLEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            complement(665..1240)
                     /locus_tag="ACHBV5_001784"
     CDS             complement(665..1240)
                     /locus_tag="ACHBV5_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HFM9967539.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            complement(1250..1645)
                     /locus_tag="ACHBV5_001785"
     CDS             complement(1250..1645)
                     /locus_tag="ACHBV5_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HFM9967540.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEIIEPAQADDIRKVVGELAKDISITKLYMTGHSLGCYLAQIAAVEAYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            complement(2121..2930)
                     /locus_tag="ACHBV5_001786"
     CDS             complement(2121..2930)
                     /locus_tag="ACHBV5_001786"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFM9967541.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            complement(2930..3487)
                     /locus_tag="ACHBV5_001787"
                     /pseudo
     CDS             complement(2930..3487)
                     /locus_tag="ACHBV5_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893195.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            complement(3489..4700)
                     /locus_tag="ACHBV5_001788"
     CDS             complement(3489..4700)
                     /locus_tag="ACHBV5_001788"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFM9967542.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            complement(4714..5397)
                     /gene="rpiA"
                     /locus_tag="ACHBV5_001789"
     CDS             complement(4714..5397)
                     /gene="rpiA"
                     /locus_tag="ACHBV5_001789"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFM9967543.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            complement(5679..6551)
                     /locus_tag="ACHBV5_001790"
     CDS             complement(5679..6551)
                     /locus_tag="ACHBV5_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFM9967544.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            complement(6693..7550)
                     /locus_tag="ACHBV5_001791"
     CDS             complement(6693..7550)
                     /locus_tag="ACHBV5_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFM9967545.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(7704..8438)
                     /locus_tag="ACHBV5_001792"
     CDS             complement(7704..8438)
                     /locus_tag="ACHBV5_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFM9967546.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESRKVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            complement(8438..9121)
                     /locus_tag="ACHBV5_001793"
     CDS             complement(8438..9121)
                     /locus_tag="ACHBV5_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFM9967547.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            9311..9541
                     /locus_tag="ACHBV5_001794"
     CDS             9311..9541
                     /locus_tag="ACHBV5_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HFM9967548.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            9770..12028
                     /locus_tag="ACHBV5_001795"
     CDS             9770..12028
                     /locus_tag="ACHBV5_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFM9967549.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKTEVKSSEKEK"
BASE COUNT         3643 a         2777 c         2241 g         3642 t
ORIGIN      
        1 tagtttgctc tttgattttc attgagtatt aattttgttc tttcacagag agctacctga
       61 gttctattca agctcaggta gtactttctt ataaactaga caaactaact gtcattgtac
      121 catcagatta caagacatca tcgtcactca ccttggaatt caatgtcgta ccccaatggg
      181 taattttacg gtggggttga gctaaaattg gtctgttttc atagattgtt tgccatctat
      241 tccatagtag gcccgtcttt ttctcaatct taactcgcag atttctcata ttttctttga
      301 ttgggaggtt gaggacaaaa cctgcagtct ggttgcgacc gtttccttcc caagaatgac
      361 tacgaacaac ttggtttcca tctttatcta ctgtaacttc ttcccaagtt atggagtagc
      421 gggcaatgta agctccactg tgttgaattg tcaatgtttt atctttcaca ggagtctgac
      481 tgattggttg aactggctta gaaacttgtg tcgccgtttc agcattcgta gctataaagc
      541 ggaaaacttc aacttctgca agactgaggg cattatagcc ttctagccca atccgaacat
      601 agcgcgcttt tttatggtta atcgtaattt gtgctgacac atctttagga gatattatac
      661 gttttcactc aatttcttta ccagaactgt ctaaaagaat gacatcaaag tttgccaatc
      721 tatcctgggc agtgtctgtt cggttgtaaa tattgatttg gcgaatggtt tcttctttag
      781 ccaaatctac ttgccaccaa ggcttagatt ggaagtttgt atgagtgaca gaattgtgac
      841 catagttacc atcgactttg ccatccacag ctcttctagc atctcctccg aaagctgtcg
      901 aactttgagt aacctgtttt cctaaggcaa tattttccat tggttcagcg cttggttgac
      961 tagaagattg aggtagagcc tgtttcttaa agaatcgcac tttatccaat ttcggatcac
     1021 gataaccatg tttatccaag gtagcttgtt taccaatatt aaagttagga atatcattca
     1081 ttggactttc aaaatagcca cgagaacggt gtttaaagcg tgaattacct gtaaatgtaa
     1141 caatatcacg attattatga atcaagggag tcacaacatt gtcattatca accacataat
     1201 gcttaatttt tccactaaca gctaatttac gactttccaa accaacatct cagaaaccat
     1261 tcttagcatc ccaaacagtt ctggaagtaa tcactttagg agcactgaaa gttgtcactt
     1321 tcctcaatac atggttataa aaatcaggat atttttggta agcttcaacc gctgcaatct
     1381 gagctaggta acatccaaga gaatgacctg tcatatacaa cttagtaata cttatatcct
     1441 tggctaattc cccaacaacc ttgcggatat catccgcttg agctggctct attatctcta
     1501 cttttgactc ttcccttttg ttttcaagaa cttcacttgc ttccggaagc gtttgaggag
     1561 ctagtcttgg ctcctctcta agaggagttt ctagttttgg agcatcattt tctgactctt
     1621 tcaattcctc cttagaatct agcacaccta ttaccacttc agatgttaca tcttgcttta
     1681 cttcattggc tgaaattcca gctggagcta gaaatcaaag ccgactacaa cagatacaac
     1741 tccgatactt aattttttat gccaaagcgc ataattcgtt gaccaatttt cattatttct
     1801 tatctttctt ttcgtttatt tacaagcaga ctcaagcgaa atctcattgt gctatatatg
     1861 ataagactga gaaattcaga aagtcaattc attctcatct ctccttatca tactagtcta
     1921 cttggctagg aagctaatgc tagtatccta gaatcttgtc tttcacaatg ctggctatca
     1981 gatcagacac acctattctt ccgcttcttt cagttataag agcaggaaga agctcatagt
     2041 attcctctgt ttcttcttta atccggatag gcagtcaatc ctgaaaaaac agaggcactc
     2101 ccccttttaa atcttttttc ttacaattca gcaagaatcg ctttaagcaa gcctttgaaa
     2161 tcacctttaa cacgttcagt cacttctaca acttcttcgt gattgagttc ttcttggaaa
     2221 ccggccgcaa agttagtgat acatgaaatt cccagaactt tcaagccaga gtgggccgcc
     2281 acgataactt caggaaccgt agacatacca actgcatctg ctcccagtgt cttataggaa
     2341 cgaatttctg ctggtgtttc ataagtcgga ccagtaactc cgatatagac accttcatca
     2401 agcttgatat taagtttttt agccacttca tgggcagtgg cacggtattc tggtgtgtag
     2461 gccctagaca tatctgggaa acgtgggcca aagtcatcca agttttcacc catcaatgga
     2521 ttttgccccg tcatgttgat atggtctgag atagccatca aggtaccagg accaaatccg
     2581 ataccgccag ctgcattggt tacaataaca ccttcacatc caagaacttt catcacacga
     2641 actgggaaag tcaccacttc cagaggattc ccttcataga aatggaaacg cccttgaaga
     2701 gccaagacct tgcgacctgc cagttcacca tataccaatt taccagcatg accgactact
     2761 gttgaacggc cccagtttgg aatctcagca tagtctacta caactggatt ttcgatttct
     2821 tctgccaatt ctccaagtcc tgacccaagg attagaccga actcaggggc tgcaattccc
     2881 ttttctttca ggaaagtagc agtttcatgg attttgttta aaaatgtcat tatgtgtctc
     2941 ctttattatt ttttagcatt tgaccaattt tgtcaaaggt tttagcatta cgaatagtaa
     3001 tgtggcggta gaaaggcacc ttcagcaagt acttatgata ggcagtctta gaataggatt
     3061 cttcagaaaa tttcccccag aaaatcccaa gttttctaaa ataaagcact tcatctttca
     3121 gctctaaact ttcaactgtc gcgatgactt ggtccacatc caaaccctca gtgtaaaaga
     3181 gaaaatcttt tcgtgccaag tctctgctcc accaagctgg tagattttca agttccgcct
     3241 caaagtcctc tagactcagt aaagaaaagc tctgaataaa tggataatgg actgcaaaga
     3301 aagtctctag cttttaaacc aattgggctt tggaatctat cgaagtaaag aaaatattgc
     3361 cactgttgat gtagctctca accttttcca gtcccaagtt tgtcaattct tgacgaagct
     3421 ccgccataac gaccttattc ttactaccaa cattgatacc tctcaccagc aaagcatagc
     3481 gcgtcatctt ataccaattt atctaagaaa ctttccccaa tcatagcagt ttccacacca
     3541 aagttatcgg caacagtcgc tgaaatatct gcaaaatgtc ctactggaat gagaccattt
     3601 cctttaaagg cagggctata tgccaacaat ggaatatatt cccgagtgtg atccgtccct
     3661 gcatacgttg ggtcatttcc atggtccgca gtaatcaaga gaaggtcatt ctctctcata
     3721 gctgcgataa tttcaggtaa gcgttcatca aactcatgca aacaatcacg gtaaccgtga
     3781 gcattacgac gatggccgta aagggcatca aagtcaacta ggtttgtgaa tgagaatcct
     3841 ttttcaaact cagcaagtcc catagtcttc aatagtgtat caattccatg actatttgac
     3901 ttgttgtgac ccatgtcatg gttgatacca gcaccgttaa agatatcgtt gattttaccc
     3961 acagcataag tatcgatacc agcctcattc aatttatcca aaacagttgg ggaaaatgga
     4021 gatacagcca agtcacgacg gtttgccgta cgagtgaagt tacctggttc acctacataa
     4081 gggcgagcaa tgatgcgacc aagaagggca ggacgctcaa gggtaatcga acgagcgtat
     4141 tcacagatac ggtacaattc atccaaagga ataatgtctt cgtgggcagc aatctgcaaa
     4201 acagggtcag ctgaagtata gataatcaac tctccagttt ccatctgacg tggtccaaaa
     4261 tcatcgataa cagccgttcc tgaataaggt ttgttggctt cacgaataac cttgcgtcct
     4321 gagaattctt cgatttttgt caggatttct tctgggaatc cgttccagaa agtatcgaaa
     4381 ggctcagtaa tgttgagtcc catgatttcc cagtgtccag tcatagtatc cttaccaaga
     4441 gatacttcct ctaattttgt tgcatatcca gttggattga tttcagctgc tacagtctta
     4501 agaggagttt cacgaggaat atttccaaga cctattttag ccatgtttgg gacattcaaa
     4561 ccaactgttt ttgaaatgtg tcccagtgtg tcagaagctc catctggaac ccctgcattg
     4621 acaaagttat tagcatctgg tgctgcaccg attcctacag aatccagtac caccaaatga
     4681 atacgattaa atttagacat cttatgcccc cttctatttt cctttttttg aagttgaaat
     4741 ctgaactcca tctcgtccag caacgattac cttatccacc atttggttga ataaaccatg
     4801 ctccacaaca ccaacgacat ggtccaattc ttgtccaaaa gcaattggat tttcaatgac
     4861 atccaaggcg aggtcaatga taaaattctg catatccgtc acaaaacgtt ggccgtcttt
     4921 ttcacggaaa cttggtttgt agccagctcg ttcaaaatga cgaaagacct gctctgcacc
     4981 atactgaacc acttctactg gcaatttaaa agcacctagt ttttcgacca gcttgctttc
     5041 atccaccacc caaatgtatt cttttgatgg tgttgcgacc accttttcca tgagaagggc
     5101 accaccaccg cctttgattc cattaaactg actatccact tcatccgcgc catcaaccgt
     5161 cacatcgaca aagtctactt ggtcaataga cttgagcggg atattaaggc cttctgcctg
     5221 tttagtggtc acactagaag ttgttacagc tgtaatctgc aatccttctt ccttgatacg
     5281 acgaccgatt tcttcgacaa aataataggc agtcgagcct gttccaagtc caacgaccat
     5341 tccatcgctc acgaactcag cagccttgat acctgccatt ttcttcagat tttccaccga
     5401 tttacctcca tcattctcag ttcttatttt actatgaaac cgctttttat tcaagtaaaa
     5461 acatcaaatc tacatttttc atcaatcttt ctttaaaaat atgcatttta tttttaccaa
     5521 acgaataaaa atgagtttat cttttatgta tttgatttgt tcatctcttt ccagttacaa
     5581 aaacaaactc ttaactttga tacgtctagt ttagccttaa agcaggcgca tttcaagaat
     5641 cataaattaa gagaaggaag tagatttatc tgtctatttt aaacaagttt atctttgctt
     5701 accctctctt gttgacaaat aattttcatt attttgggaa gatacctgct gatttccgtc
     5761 ggtaagacca cataattttc ctgagatagt tcttgggcta tggctgaatg aagatgggtc
     5821 gctactgcca cacgctcgta gagactggcc tgtcggaatt ggcctacaaa tcctgcgatc
     5881 atcccagcca gagtatctcc cattccccca gtcgcctgat aaggaccacc aacctgtaac
     5941 tggtaataat cagattggcc aacttcccaa atacgagtag ctgggccttt ctccaccaaa
     6001 attgttcctt gagggaagga agtcagaaca ctagccgttg catcttcctt ttgcttttca
     6061 atcgtaattc cagataattt ttcccattct ttttggtgag gagttaggat aagctggctt
     6121 gagggaaatg acaaacttgt cctagcaaga atggtcaagg cacctccgtc tacaatcaaa
     6181 atctgatttt ggcttaaatt aacaaagacc tgttttacta gattttctcc agaagcatcg
     6241 tctcgtaaac caggccccaa caagacaact tctgccttct ccaattgctc ttttaacaat
     6301 tgctggtctt gaagagaaaa ggccataggc tcaggtaaat ggctgtgcag agccgggata
     6361 ttttccctgt ccgttccaac ggtcaccaat cctgcaccgc tttttacagc tgctaaagca
     6421 gccatgatga tggcacctcc ataaggataa gtaccaccaa gcagcagcag acgaccataa
     6481 tctcctttat gacttgaacg agaacgttca ataataactt tttctaataa ggtttgatta
     6541 atcactttca tccttttttc ctctcacttt tattatacaa taaaaaggag acgcagacct
     6601 ccttttgtaa tcttatatct aaaatttaat attcatttct gccattttag atatagctat
     6661 agaaaataca ctctattaat cgaatgtttc tcttattttc tatccaatgt ccgaagtgct
     6721 gcttgataag tttgctccat cagcatggta atggtcatag gaccgacacc tccagggact
     6781 ggcgtgatat agctagcaag tggtgcaact gcctcataat caacatctcc acagagcttc
     6841 ccattttcat ctcggttcat cccaacgtca atgacaaccg cacctggttt gacaaagtca
     6901 gcagtcacaa acttggcgcg gccgattgcg actacaagaa tatctgcttt agcagccacc
     6961 ttggcaagat tatgagttcg tgagtgggtc aaggttactg tcgcattttt agccaaaaga
     7021 agctgagcca taggttttcc aacgatattt gaacgaccga tgacgaccgc atttttacct
     7081 tccaagtcaa tcccatattc atgaaacatt tccataattc ctgcaggtgt cgagggaatc
     7141 atgactggat gtccagacca aagacgtccc atgtttaagg gatggaaacc atccacatcc
     7201 ttttctgggt caatggctaa taaaaccgcc tcttcatcga tatgttttgg taatggcaac
     7261 tggaccaaaa tcccatgcca agctggatcc tgattatatt tagcaatcag gtctaacaat
     7321 tcctcttgag taatggtctc tggaactcgc actacttcgc tacgggaacc agccgcaaga
     7381 gctgacctct ccttgttgcg aacgtagact tggctggctg gattatcccc aaccaaaatc
     7441 actaccaaac caggcactag agctgtttct tcctttaatt ttgcagtctt ttcagccaac
     7501 tgcccctgca atttggccgc taaagctttc ccatcaataa tctgtgtcat atcacttctc
     7561 ttttctttca aatatcttcc attataccaa aaactgctag tgccctctaa cacttctttc
     7621 ctaggttatc ctatagtttc aaactataag aaaaagctct ggttgaactt ttcactaatc
     7681 ttgtcttgaa attttaaaat agattataaa accttactca agaaatcttt agtccgttgt
     7741 tcttgggttt gttcaaaaat ctgctcaggt gtcccatctt caacaaccac accgtctgcc
     7801 ataaagataa cacgatctgc cacctcacgg gcaaatccca tctcatgtgt tacgataacc
     7861 atagtcatcc ctgacttggc aaggtcttgc ataacagcca atacctcacc taccatttca
     7921 ggatccaagg ctgaagttgg ttcgtcaaag agcaaaacat ctggttccat agccaaccca
     7981 cgcgcgatgg caatccgttg ttgttgccca cccgacagac tctgtggata agcgtctgcc
     8041 ttatctggca aaccaacttt ttccaaaagc tcttgggctc tcttctcagc aactttcctg
     8101 ctttcacctt tagtcttgat aggtgacaag gtaatatttt ccatcacagt catattagga
     8161 aagaggttaa attgttggaa aaccatgccc atcttctcac gcatggcaaa caggtcattc
     8221 ttcttgtccg taatatcgac tccctcaaag ataaccttcc ccttggttgc ttcctccaac
     8281 aaattcatag agcgaagcaa ggtagatttc ccactccctg aaggaccgat gataacgaca
     8341 acttctcctc ttttaatctc gaggttgatg cccttcaata cttcattctt tccaaaagat
     8401 ttatgtaaat tttcaatttt tatcaaggtt tctgtcatta tttcttatct ccttgtccca
     8461 tatgtttttc aaaagctttc aaggctactg tcagaataga ggtcataatc aagtagtaaa
     8521 atgctgcaaa taaaagtggt gttaaaggta gataggttgt tgtagaaact gttgtagccc
     8581 cattccacaa ctccatgacc ccaatagctg ataagaggga gctgtccttg ataatggtga
     8641 taaattcgtt ccccaatgct ggcaagatat ttttgactgc ttgtggcaaa atcacataac
     8701 gcatcgcatt tttaggacga atccctagcg aataagccgc ctctagctga ccttttggaa
     8761 ccgcattgat tccggcacga acagtctccg aaacataagc accactattc atagagataa
     8821 tcaaaatccc tggaatcaga cgcgaaaaat caacacctaa aattccaatc tgaatagtcg
     8881 gagcattgat atgcataaga gcaaaggcaa tcataatttg aaccatcatc ggtgtcccac
     8941 ggaaaatcca aacgtacaag ttggccaacc aaacaagcgg tttaaacttt gaacgttgcc
     9001 caaaagccaa gacaacaccc aaaatagttc ccaaaaagat aacacagata gaaataagaa
     9061 tcgtcacaac agccccatag ttaaaataag gtaaatactt aggtaaaaaa gaaaaattca
     9121 tagtcacact gctttctaaa atagaatact gtatgattat aacatgtttt gaattaaaat
     9181 ttaaattttt tatccaattt atttaaaaat ctttaaacta gcagaattaa cgagaaatct
     9241 tagttttttc tagtcaagtt ggcctccttt atggtaaaat agtaacgata agaaatgaag
     9301 gagaatcaaa atggaatcac atttggttag aatcatcaac cgccttgaag caatggcaaa
     9361 cgatggcgga aatttaaaac gtaattttga acgcgaagga gttgttgttg cagaagttgc
     9421 gtacagccac gacgaagaaa acggcccaat ctttaccctt cgtgacgtag aagatcgcga
     9481 aacgtatacg tttgatagca ttgacttaat cgcaatggaa atttacgaac ttctctacta
     9541 atctaaaaca agctgggatt gtccctgcat gtctaagtaa aatccttttt gtctcacaaa
     9601 taggattttt ttatagtcca aattcacaaa aattttcatt gtaacaactt ctcaaagctt
     9661 caatcttttt acttgcttta caccccaatc ctgttataat gagagtatag aatttgacta
     9721 tttttgacct ttaaacaagt caggctaaag aaagaaatga ggtagatgta tgctttgtca
     9781 aaactgtaaa attaacgact caacaattca tctttacacc aatctcaatg gaaaacaaaa
     9841 acaaattgac ctctgtcaaa actgctataa gattatcaaa acagatccta acaatagcct
     9901 cttcaaaggt atgacggatc tgaacaatcg tgacttcgat ccctttggtg atttcttcaa
     9961 tgatctaaac aatttcagac cttctagcaa tactcctcct attcccccaa cccaatcagg
    10021 tggaggttac ggtggaaacg gcggttatgg ttcccaaaat cgtggatctg ctcaaactcc
    10081 gccacctagc caagaaaaag gcctgctgga agaatttggt attaatgtaa ctgaaattgc
    10141 ccgtcgtgga gacattgacc ccgttattgg gcgcgacgat gagattatcc gtgtcatcga
    10201 gattctcaat cgtagaacca agaataatcc tgtccttatc ggtgaacctg gtgtcggaaa
    10261 aacggccgtt gtcgaaggtc tagctcagaa aattgtcgat ggcgatgtgc cacataaact
    10321 ccaaggtaaa caagtcatcc gtctggatgt ggttagctta gttcaaggaa cggggattcg
    10381 aggacaattt gaagaacgca tgcaaaaact catggaagaa attcgcaaac gtgaagacat
    10441 catcctcttt atcgatgaaa tccatgaaat tgttggtgct ggttctgcga gtgatggtaa
    10501 tatggacgca ggaaatatcc tcaagccagc ccttgctcgt ggagaactgc aactagtcgg
    10561 tgctactacc ctcaatgaat accgtatcat tgaaaaggat gctgccctcg agcgtcgtat
    10621 gcagcctgtt aaagtcgatg aaccaacggt ggatgaaaca atcactattc tcaaagggat
    10681 tcaaaagaaa tacgaagatt accaccacgt tcaatatacc gatgctgcga ttgaagcagc
    10741 tgcaactctt tccaatcgct acatccaaga tcgcttcttg cctgacaagg ccattgacct
    10801 cctagatgaa gctggttcta agatgaactt gaccttgaat tttgtggatc ctaaagtaat
    10861 tgatcagcgc ttgattgagg ctgaaaatct caagtctcaa gctacacgag aagaagattt
    10921 tgagaaggcg gcctacttcc gcgaccagat tgccaagtat aaggaaatgc aaaagaaaaa
    10981 gatcacagac caggatactc ctatcatcag cgagaaaact attgagcaca ttatcgagca
    11041 gaaaaccaat atccctgttg gtgatttgaa agagaaagaa caatctcaac tcatccatct
    11101 agccgaagat ctcaagtctc atgttattgg ccaagatgat gcagtcgata agattgccaa
    11161 ggctattcgc cgtaatcgtg tcggacttgg tacccctaac cgcccaatcg gaagcttcct
    11221 cttcgttggg ccaactggtg tcggcaagac agaactttcc aaacaactgg ctatcgaact
    11281 ttttggttct gctgatagta tgattcgctt tgatatgagt gaatacatgg aaaaacatag
    11341 tgtggctaag ttggtcggcg ctcctccagg ttatgttggc tatgatgagg ctggtcaatt
    11401 aactgaaaaa gttcgccaca atccatattc tctcatcctt ctcgatgaag tggaaaaagc
    11461 tcacccagat gttatgcaca tgtttcttca agtcttggac gatggtcgtt tgacagacgg
    11521 gcaaggacgc accgttagct tcaaggatgc tatcattatc atgacctcaa atgcaggtac
    11581 aggaaagacc gaagctagcg ttggatttgg tgctgctaga gaaggacgta ccaattctgt
    11641 cctcggtgaa ctcggtaact tctttagccc agagtttatg aaccgttttg atggcattat
    11701 cgaatttaag gctctcagca aggataacct ccttcagatt gtcgagctca tgctagcaga
    11761 tgttaacaag cgcctctcta gcaacaacat tcgtttggat gtaactgata aggtcaagga
    11821 aaagttggtt gacctaggtt atgatccaaa aatgggagca cgcccacttc gtcggactat
    11881 tcaagactat attgaggaca caatcactga ctactacctt gaaaatccaa gcgaaaaaga
    11941 tctcaaagca gttatgacta gcaagggaaa cattcagatt aaatctgcca aaaaaactga
    12001 agttaaaagt tctgaaaaag aaaaataaat cctataaaaa aagagtagaa aatgaaattt
    12061 ttctgcttct ttttttacta aaataactgt aatttcttga cagcttgccc tttgtccatt
    12121 atgatatata gtagactgaa tctgaaatag tacgaaacaa ttgctaaaac atttatagaa
    12181 attaatttta ctttccaaat cgatttgttc tcatcttatt tcaatctgct acagtcaatt
    12241 gaaacaagaa caggacaaaa gagcctcgta aaaggtattg taacttggta ataccttttt
    12301 gag
//
LOCUS       DAYYYC010000057        12045 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.057, whole genome shotgun sequence.
ACCESSION   DAYYYC010000057 DAYYYC010000000
VERSION     DAYYYC010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12045
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.057"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(140..1342)
                     /gene="rpsA"
                     /locus_tag="ACHBV5_001796"
     CDS             complement(140..1342)
                     /gene="rpsA"
                     /locus_tag="ACHBV5_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFM9967550.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRVARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1504..1575)
                     /locus_tag="ACHBV5_001797"
     tRNA            complement(1504..1575)
                     /locus_tag="ACHBV5_001797"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1541..1543),aa:Gln,seq:ttg)
     gene            complement(1585..1665)
                     /locus_tag="ACHBV5_001798"
     tRNA            complement(1585..1665)
                     /locus_tag="ACHBV5_001798"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1629..1631),aa:Tyr,seq:gta)
     gene            complement(1715..1945)
                     /locus_tag="ACHBV5_001799"
     CDS             complement(1715..1945)
                     /locus_tag="ACHBV5_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFM9967551.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2113..2757)
                     /gene="pcp"
                     /locus_tag="ACHBV5_001800"
     CDS             complement(2113..2757)
                     /gene="pcp"
                     /locus_tag="ACHBV5_001800"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFM9967552.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2772..3695)
                     /locus_tag="ACHBV5_001801"
     CDS             complement(2772..3695)
                     /locus_tag="ACHBV5_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0859 family membrane protein"
                     /protein_id="HFM9967553.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3692..4381)
                     /locus_tag="ACHBV5_001802"
     CDS             complement(3692..4381)
                     /locus_tag="ACHBV5_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0858 family membrane protein"
                     /protein_id="HFM9967554.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4446..5150)
                     /locus_tag="ACHBV5_001803"
     CDS             complement(4446..5150)
                     /locus_tag="ACHBV5_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM9967555.1"
                     /translation="MVLSTLAILVACGKTDKEADAPTTFSYVYAVDPASLGYSITTRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPIVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            complement(5206..6228)
                     /locus_tag="ACHBV5_001804"
     CDS             complement(5206..6228)
                     /locus_tag="ACHBV5_001804"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFM9967556.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6358..8829)
                     /gene="parC"
                     /locus_tag="ACHBV5_001805"
     CDS             complement(6358..8829)
                     /gene="parC"
                     /locus_tag="ACHBV5_001805"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFM9967557.1"
                     /translation="MSNIQNMFLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKNFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9030..9234)
                     /locus_tag="ACHBV5_001806"
                     /pseudo
     CDS             complement(9030..9234)
                     /locus_tag="ACHBV5_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            complement(9249..11192)
                     /gene="parE"
                     /locus_tag="ACHBV5_001807"
     CDS             complement(9249..11192)
                     /gene="parE"
                     /locus_tag="ACHBV5_001807"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFM9967558.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTALKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11328..11969
                     /gene="plsY"
                     /locus_tag="ACHBV5_001808"
     CDS             11328..11969
                     /gene="plsY"
                     /locus_tag="ACHBV5_001808"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFM9967559.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
BASE COUNT         3473 a         2734 c         2118 g         3720 t
ORIGIN      
        1 atcgctctga atatcaaaaa agaaaggacg aaatttgtcc tttctcgagc ttagcttttt
       61 ttcaacccac tacagttgac aaagagccag aaaaatcctt tgtttagtaa acaaaggatt
      121 ttgtgaattt tcaatttgat taaagttcga tatcaccaaa caaatcagcc attgaaaatc
      181 ctgtttgtgt ttctggaagt tcgaaatcac gcttttcttg acgtcttgga cgacgtggac
      241 gagcaacacg tttttcttct ttttgtcctt cttcttgggc tggacgttct tcaagagctt
      301 taatagaaag tgacacgcgt tctgcatctg cgttaacttc aagaacttta acttgaactt
      361 cttgaccaac tttaagagct tcttttggat tttcaatccg tttgtgtgaa atttgtgata
      421 cgtgaacaag tccatcgata cctggcaata cttcaacaaa tgcaccgaag tcagtcaaac
      481 gtttaactgt tccttctact acatcacctt tagccaattt ttgctcaacg ccatcccatg
      541 gtcctggtac tgttgcttta agtgaaagtg atacacgtcc ttcttcttcg ttaagatcaa
      601 ggattttcac ttcaatttct tcaccaacag ttacaactga ttttggtgat acattacgtt
      661 catgtgacaa ttcagtcaag tgaaccaatc cgtcaacacc accaagatcg acgaaagcgc
      721 cgaagcttgt gatacgagca actttaccag ttacaacatc accaacagcc aatttaccga
      781 atacttcagc gcgagctgct gcagtagctg cttcaacaac ttcacgacgt gaaaggatga
      841 agcggttttc tttagcgtta acttctttga ttttagtatc aaattcttga cctacaaaac
      901 gctcagcgtt acgtacgaaa cgagtatcca acattgaagc tgggataaat ccacgaacac
      961 cttcaaattc tactgaaagt ccacctttaa cggcacgcgt tcctttaaca gtaacaactt
     1021 cttcttcgcg accaacaagt ttgtcccatg ctttgcgagc ttcaaggcgt tttttagata
     1081 caaggtatgt aactgtatca gtatctttac caactacttg acgaagtaca agaacatcca
     1141 atacttctcc tactttaaca aagtcattga tatctgcatc acgatcgttt gtcaattcgc
     1201 gaagagtcaa gacaccttca acaccagttc cagagattgc aacgttagct tgagtcgcat
     1261 caactgtcaa tacttcagca ctaacaacat caccagtctc aacttgacta acgctattta
     1321 gcaaatcttc aaattcattc atctaaaaaa tcctccaaca atcaagtttt tcttaaactt
     1381 gacatactta taattttttt cctaagcacc cgcaaggaca tgttcatatc attcacgtct
     1441 ttcaattata aaaataaaat accctaagat attttgcttt ttatcttgat tattacctaa
     1501 gaactggggt agctggattc gaaccaacgc atgagggagt caaagtccct tgccttaccg
     1561 cttggctata ccccattaat gaaatggaga gagagggatt cgaacccccg aacccgaagg
     1621 agcggattta cagtccgccg cgtttagcct cttcgctatc tctcctacaa tcaacatgga
     1681 ctattatatc atgaaaattt caaaaaaaca agacttattt tgctaaatta taattttcaa
     1741 tcaaaatttc cacagctttt tccaattttt tataaaaact atcgacattc ccattcttta
     1801 taatggcaaa ttgtccgtct aattcggcaa tttctccgat aactttttta ccgatagtca
     1861 atgtataacc ttcaaaactg tctttaccaa cattaacttt ggcatccgct acttgaattt
     1921 cgattttttt atctttcttg ctcatttcat acctctcttc actttttcta ttttacaaga
     1981 aaatcctaaa actagcaaga aaaaactcta tatcaggctt ctctgatata gagttttatg
     2041 taaacaacct caatcgattt agcatagtta atagttagta aacaagcata attgactatc
     2101 ctttttaggt tatcagtgag tctcaccgcc tactaactgc aaatccttat ctttgtagtc
     2161 tacaatagct tcaatagcta cctctatgcc tcttacaata tcacatagac tcattcctgc
     2221 agtattcggc ttatttacta cttgttccat catatatgga atatgcatga aacctgctct
     2281 catattaggg aattttttat ccactaaata aagagcttgg tacatcaaat gattgcaaac
     2341 aaaggttcct gcactattgg atacaactgc cggaagtccc tgttttttga tagcttgtac
     2401 catcgctttg ataggtaaac tactaaaata ggccgatgct ccatcaatac gaatcggtgt
     2461 atcaattggt tgattgcctt cgttatcagg tatgcgagca tcatcttgat taatagccac
     2521 tcgttcaggt gttaagccgg tcctgccgcc tgcttgtcca atacaaagta cagcatctgg
     2581 ttgatatcgt aatatttctg cctctaaaac ttctgacgac ttataaaaaa ccgttggaat
     2641 ttctacccag cgaacttcag ccccattaat ctcagatggt aataatttta cagcctccaa
     2701 agctggatta atcttttcac ctccaaaagg attaaaacct gtaaccaata ttttcatttt
     2761 attttccttt actaaaatgc gagaaagtac attaagaata tgtgaataac aatcattact
     2821 agagcaacac ctgcttgagc ctttataacg ccattctgat ctttcatatc catcaatgct
     2881 gctggtagag cgttaaaatt agcagccatt ggggtcaata aggtcccaca ataacctgct
     2941 gtcatggcaa gagcaccagc cacaattgga ttagctccca gagcaaatac gaagggaact
     3001 ccaacacctg ctgtaataac ggtgaatgct gcaaaagcat ttcccataat cattgtgaat
     3061 agaaccattc caagaacata ggccaaaact cctataaagc gactatctga aggaacaata
     3121 ccgctaatca gatgagagat aacatcacca acacctgcta cagtaaaaat agcccccaaa
     3181 gcccctaata attgaggaac aatcccactt gttgaaactt gctgagtcat tcgattattt
     3241 tctgataaca gactcttagg gtgactattg gtaatcacaa gaacagaaat tgtagcaaac
     3301 aaggcggcaa ggctaatcga aatcttgcta aattctggaa tcatttgcgc taagaccaac
     3361 gcaagtattg ccatcagcat aactggaata aaaattttat ttttcaacct gttagattca
     3421 atattggctt tcatttcatc taaggatggc aaggttccga tacggacttg cttaaacaat
     3481 gttaacagcg ataataggat tacaataata ccaatactca tatttggcat ataggaacca
     3541 cctataaacg taatagacaa tagagtccaa aatgcagatg tcccaagtcg aactgggttt
     3601 gttttatctt tataactaca ataggctgta tggagaaatt gacaaccaat cacaatatag
     3661 gtcaactcta atagttgctt tgccaactct gtcatttttg ttctcctccc ctagtctttt
     3721 ttgatatcaa ttttttatca aataaataat tgtaaatccc cactacaata agtgttataa
     3781 cagcaacaat aatagatgta gaagcaatcc ctgcataatt gctttcatag cctaactgat
     3841 ctaatgttcc ccctatcaag aggactcccc cagcacctac aaacgtattt tgagcaaaga
     3901 aatttccaaa attttcattc gcagccgcac gcgcttttat tgtctcatct tcaacctctg
     3961 ttaactttct acctaattga gactctgcag ctgcttctcc cataggttga accaaaggtc
     4021 tgacaaactg agggtgtcct cctagacgaa ttgaaaagaa accagctaac tctcgaataa
     4081 agaaataaac tgtatagaag tttccaactg tcagaccttt aatctttcga atcaaatcga
     4141 ttgatcgttg cttgagtcca aaggtttctg acagccccac aagaggcaag gtaaccataa
     4201 aaatcgtgag cactcgctga ttgctaaatt cttttcccaa aatctccaaa aattcaacga
     4261 gagaaacacc tgaaactaaa gctgtaacca aaccagctaa gactactgtt gcaattgtat
     4321 caaattttaa aataaaaccc acaacaatga ttgctattcc tattaatcta atccactcca
     4381 tatcaaactc ctttatattc aaaatgacag tattttaaaa attttatcaa gatcaatacc
     4441 attccttatt taatgtgttt ttctagttct ttttggtatt tgctattgga ttccaatttt
     4501 tctttttgcc attttttaaa aacctcgtta tattcttttg ttgtaacaat atctttttgc
     4561 aatttcattc ctttaaagat atatggttcc cccttaatac caacttgtga gtatggtttt
     4621 gagaatggta ctacgttact tacaattgga gaaccaccag atgaagctgt tggcatcaat
     4681 aatgaactat ctgtcgacca agcttgagct ttggcatatt tttcatatct cttctctagg
     4741 tcagtggtct cagaaacagc atcttctaac aatttcttat atttatccaa accaggttta
     4801 gctacaacat ccttatcttt tcctttcgta ataccaaggt gtttcatggc agaaccagat
     4861 tttggatcca taatattcaa gtaagacgct ggatcttgat agcttggagc ccatcctgta
     4921 ctattcaaat catagtcttt ttgagaagga gcaacattgc cgtatttatc attttccatc
     4981 aaaccatcaa taacatttcc aataacgtct gtcgtcgatg ttcgagtcgt tatactgtag
     5041 cccaatgatg ctggatctac tgcatagaca taagaaaatg ttgtcggtgc atctgcttct
     5101 ttatcagttt ttccacaagc cactaaaata gctaacgtgc tcaggaccac tcctgctgtt
     5161 aagagccact ttttctattt cataaaaaat ctcctttggt ttattttaat ctacttttac
     5221 aatccaacct tctggcgctt caatatcgcc aaactgaata cccgtcaatt cattatataa
     5281 tttacgcgtc acaggaccta cttctgtttc actatagaat acatggaaat catcaccatg
     5341 ttgaatacct ccaattggag aaataaccgc tgctgtacca caggcacctg cctctacaaa
     5401 acggtcaaga ttatcaattg gaacatcacc ctcaatagga gttaatccca agcgatgttc
     5461 tgccaaataa agcaaggaat acttggtaat agatggcaag atagatggac tcaatggtgt
     5521 tacaaattca ttatcagctg taattccaaa gaaattagct gatccgactt cttcaatctt
     5581 tgtatgagtt gatgggtcca gatagataac atctgagaaa tggcgtgact tggccatttt
     5641 tcctggtaag agacttgcag catagtttcc accaacctta gccgcacctg taccatttgg
     5701 tgctgcacgg tcgtactcat cctgaatcaa gaagttggtt gggaccaaac cacctttaaa
     5761 gtaatttcca actggcatag caaagatggt gaaaatgtac tcttctgccg gttttacccc
     5821 gataatatct ccgacaccaa tcaaaagagg gcgaagatat aaggttccac ctattccgta
     5881 tggtggtacg tattcttcat tcgcacggac aactgcttta caagcttcta caaacatgtc
     5941 tgtcggaact tgtggcatca agagacggtc acatgtacgt tgcaggcgtt tagcattttc
     6001 atcaggacgg aacagttgaa cactgccatc cttagtacga taagctttca aaccttcaaa
     6061 tgcttgttgt ccatagtgaa gacttggaga agactctgaa atatgcaaag ttgcatcctc
     6121 tgtaagctct ccttgatccc attgtccatt tttgaaatga gcaagatagc gataaggtaa
     6181 tttcatatag gaaaaaccga ggttttccca atcaatcgtt actgtcatat tccactcctt
     6241 attctaaaaa cctatttctt atattctaca ctatttttct aaaatagcaa gtatattttg
     6301 taattttcag aaaattcctc caataaaaac catcttagaa ctgattcttc atttcactta
     6361 tttatcttca gtaactactt cctgaagata agcgtcaaaa acttcttcat ctgaaatcgt
     6421 gtcagaaatg aagcttccat tgctagtgcg ttctgacaag ttcaagtctt gcaatcggct
     6481 ttcatagatt gttcctttat tggattggac aagcagagtt tggtcgttca catccacttc
     6541 cgtactgaag aaatcgccaa caaatccttg ctctgcaact gctcctgcca agaagacacg
     6601 atgcggtttg tttttcaact cacgcaagac ttgtaatcct cgtttggcac ggctggttgc
     6661 tagaatttcc tcaatggaaa cacgtttcaa gcttccacgc tgggtcaaga ggtagaagga
     6721 cgaagtatta cagataaagc cagattggag gacatcatct tctttcaaat tcatagcctt
     6781 gacacctgct gccttagcac cgacaaccgg aacctcttcg atattgaaac gcagggcata
     6841 accattttga ctaaccaaga caacatcatc tagtttaatc ggagccactg ctacaatctg
     6901 atctgtatcg tctttgagct tagcatactt gacagactta gatctatagg tccgccatgg
     6961 agtgaattct tttcgctcta cccgtttgat ttgaccaagg cgagtcgctg caaagtaggt
     7021 tgtcgcatcg tcaaactgat ccagtacttc cacataaagg attgcttcat tcgtttcaaa
     7081 gtttgtgatg gtttggctca gatgctctcc gatgtccttc caacgaatat ctgccaactc
     7141 atggattggt ctgtagatga catttccaag acttgtgaac atcaagaggt gctgggttgt
     7201 cttggcagat tgaacaaaaa tcaaacggtc atcatcacgc ttgccaattt cttccaaggt
     7261 ggaagccgca aaggaacgtg gactggtacg cttgatgtaa cctgccttgg tcacgctgac
     7321 gtaggtatct tcctcagcga taagactagc tgtatcaatc tcaattgctt tcgcagtgtc
     7381 ttctaaagaa ctcaaacgag gagttgcaaa gttcttcttg acctcacgaa gttctttctt
     7441 catgagattg tacatagtcc tttcatcacc gataatagcc gccagcatag caatcttctc
     7501 acgaagctct gcttcttctt cctgcaagac aaccacatcg gtattggtca aacggtacag
     7561 ttgcaaagtt acgatagcct cagcctgttc ttccgtaaaa tcatagctaa ctttgaggtt
     7621 ttccttggcg tccgccttat tctcagaagc acggataaga gcaatgactt catccaaaat
     7681 cgaaatcaca cgaatcaaac cttcgacgat acggagacgt ttctcagcct tttctttgtc
     7741 aaagcgtgaa cgcgccaaaa tcacttctcg acggtgagcg atgtagctag acaggattgg
     7801 aacaatccca acctgacgag gtgtgaaatt gtcaatcgcc accatattaa agttgtagtt
     7861 gatttgtagg tcggtgtact taaataagta gttgagaaca agctcagtat tagcgtcttt
     7921 cttaagttca atagcgatac gaagaccatc acggtcagac tcatcacgaa cctcagcaat
     7981 cccagctacc ttgttattaa cacgaacatc atcgattttc ttgactagat tggccttatt
     8041 gatttcataa ggaatctcag taataacgat ttgttcctta ccacctttta gcttttcaat
     8101 ttcagtcttg gaacgaacaa ccacgcgccc tttcccagtc tcataggctt tcttgatttc
     8161 atcacgaccc tgaataatag cccctgtagg gaagtctggt ccaggtaaga attccatgag
     8221 tttatcaatc tttgcagttg ggtggtcaat catgtaaact gcagcatcta tgacctcagc
     8281 taaattatgg ggaggaatgt ctgtggcata accagccgaa atcccagtcg aaccattgac
     8341 caagaggttt ggaaaggctg ctggcaagac cgttggttct ttctccgtat cgtcaaagtt
     8401 ccatgcaaaa ggaactgtct ttttctcgat atcctgaaga aggtagcctg caatttcaga
     8461 caaacgtgcc tcagtataac gcatagccgc aggaggatct ccgtccatag aaccgttatt
     8521 accgtgcatt tcaactagaa tctcacgatt tttccagttc tgtgacatac gaaccatggc
     8581 atcatagata gaagaatccc cgtgtgggtg gaaattcccc atgatgttcc cgactgactt
     8641 ggccgactta cggtagctct tgtcaaaagt attgctatcc ttattcatag aataaagaat
     8701 acggcgttga accggcttca acccatcacg aatatctggc aaagcccggt cttgaataat
     8761 gtacttggag tagcgaccaa agcgctctcc catgatgtcc tccaggaaca tgttttgaat
     8821 gttagacata agatacaaag cccataaaat accaagtgaa aatagaaaat tcttgaagta
     8881 agcaaactca caagagaatt tatctttttc acacagtatc tagggcgtgt tcaactcctt
     8941 tcaaagaatg tagagtaggt ttttatgcag taaaagatat tttacgggaa ttcgtcccgt
     9001 gttcagttac gataagtaac caaactatcc tgtttgtatt tttcaatatg aaaatctggt
     9061 tttccaaaat tagtcttagt ttgtgtctta accgctccct taagcgcctc tttaagataa
     9121 gcactcatag cagattcttc attaataatc ctgcaatttt ttcaaaccaa gattttcaaa
     9181 ctgctttttc acatagtcat tcacatccga ctctaatttc cagtttacta acatattatt
     9241 ttctttcatt aaaacactgt cgcttcttct agcgtaaact tgacattatc ttcaatccat
     9301 ttacggcgtg gttctacctt atctcccatg agaacattga cgcggcgttc ggcgcgcgct
     9361 aaatcttcaa ttgtgacacg gatgagggta cgtgtttctg ggttcatggt tgtttcccag
     9421 agctggtccg cattcatctc accaagtcct ttgtatcgtt ggagggtagc gcctttaccg
     9481 aactgtttac ggagttcttc tagttctccg tccgtccaag cgtaggccac ttcttctttc
     9541 ttgcctttac ctttggacat cttgtaaaga ggtgggaggg caatatagac atgacctgcc
     9601 tcgactagcg gacgcatgta acggtagaaa aatgtcaaga gcaaggtctg gatatgggca
     9661 ccgtcggtat ccgcatcggt catgataatg atcttatcat agttggcatc ttcaatagag
     9721 aagtctgctc caacacccgc accaatggta taaatcatgg tattgatctc ttcatttttg
     9781 aggatatccg ccatcttggc cttggctgta ttgataacct taccacgaag aggtagaata
     9841 gcctggaact tgcggtcacg accttgtttg gcagaaccac cggcagagtc cccctcaact
     9901 agatagagtt cattcttagc aggattctta gattgggctg gggtcaattt cccagacaac
     9961 aagcccttat ctttcttgtt tttcttccca tttcggctct catcacgcgc cttacgtgct
    10021 gcttcacgag catcacgggc cttgatagcc ttgcggatga ggttagaagc taattcccca
    10081 ttttccataa ggaaaaaggt caacttatca gccactattc catccacaac tgggcgagct
    10141 agggggcttc ctagtttatc cttggtctgt ccttcaaact gcaagtgttc ttcaggaact
    10201 aagatagaaa gaacggccgc tagtccctca cgatagtctg aaccttcaag gtttttatct
    10261 ttttccttga gaagacctgt tttacgtgca tagtcattca tgaccttggt aatggcagac
    10321 ttgagtcctg tctcgtgcgt tccaccgtcc ttggtgcgaa cgttattgac aaaggataga
    10381 atgttatctg agaatccgtc attgtactgg agggctactt ccacttgaaa accattgtct
    10441 tccccttcaa agtaaagaac tggcgtcaag atttccttat cttcgttgag ataagaaaca
    10501 aaatcttgta ctccattctc atagtggaac tcaatcgctt catctgttcg cttgtccgtt
    10561 aaagacaagg tcacattttt caagagaaag gctgattcat taaggcgctc tgaaatggta
    10621 ttgtacttga aatctgtcgt agaaaagata gtcgcgtcag gcataaaagt aactttggtg
    10681 cctgttttag acttgagtgc tgtaccgatt ttcttcaaag tcgtgacagg ttttccacca
    10741 ttttcaaaac gttgcttgta aactgcgcca tcacgggtaa tttcaacttc taaccagcta
    10801 gaaagggcgt taacaacgga agaacccact ccgtgaagtc cacctgatgt cttatagcca
    10861 ccttgaccga atttccctcc ggcatgaaga atggtaaaga taacctcaac agttggaatt
    10921 cccatagcgt gcatacctgt cggcatccca cgtccatggt cttgaaccgt tagactaccg
    10981 tctttattga tagttacatc aatacgatca ccaaacccag acaaggcttc atcgactgca
    11041 ttatcaacga tttcccaaac taggtgatga agaccagcgc catcggtcga tccaatatac
    11101 atccctggac gttttcggac cgcatccaac ccttctagca cctgaatagc atcatcatta
    11161 taattgttaa tattgatttc cttttttgac acaaggaacc tcctattcgt tcatctttac
    11221 tattctacag gttttccaag gattttgcaa aatttttctt tctccgatgt gacaatttca
    11281 gcagagattc tctgcttttc tttcccaatt catgatataa taggagtatg attacaatag
    11341 ttttattaat cctagcctat ctgctgggtt cgattccatc tggtctctgg attggacaag
    11401 tattctttca aatcaatcta cgcgagcatg gttctggtaa cactggaacg accaacacct
    11461 tccgcatttt aggtaagaaa gctggtatgg caacctttgt gattgacttt ttcaaaggaa
    11521 ccctagcaac gctgcttccg attatttttc atctacaagg cgtttctcct ctcatctttg
    11581 gacttttggc tgttatcggc cataccttcc ctatctttgc aggatttaaa ggtggtaagg
    11641 ctgtcgcaac cagtgctgga gtgattttcg gatttgcgcc tatcttctgt ctctaccttg
    11701 cgattatctt ctttggagct ctctatcttg gcagtatgat ttcactgtct agtgtcacag
    11761 catcgatcgc ggctgttatc ggggttctgc tctttccact ttttggtttt atcctgagta
    11821 actatgactc tctcttcatc gctattatct tagcacttgc tagtttgatt atcattcgtc
    11881 ataaggacaa tatagctcgt atcaaaaata aaactgaaaa tttggtccct tggggattga
    11941 acctaaccca tcaagatcct aaaaaataaa acgccagttc tgtactgccc ccaaacagtt
    12001 agacaaataa tttatccaaa ggatttagtt ctgtattgca caggg
//
LOCUS       DAYYYC010000058        11925 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.058, whole genome shotgun sequence.
ACCESSION   DAYYYC010000058 DAYYYC010000000
VERSION     DAYYYC010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11925
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.058"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(<1..283)
                     /locus_tag="ACHBV5_001809"
     CDS             complement(<1..283)
                     /locus_tag="ACHBV5_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFM9967560.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPSVVGGIEINVLGI"
     gene            451..1773
                     /locus_tag="ACHBV5_001810"
     CDS             451..1773
                     /locus_tag="ACHBV5_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFM9967561.1"
                     /translation="MNNILTFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRIFIQRGITIKMPNGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            1775..3661
                     /locus_tag="ACHBV5_001811"
     CDS             1775..3661
                     /locus_tag="ACHBV5_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HFM9967562.1"
                     /translation="MVIRVFDQQKNTYSSFALEELRYYMNQVFNTDIELVEEKEADIF
                     VGLVNEEDGKDHIFISLNKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFIP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYKDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            3829..4173
                     /locus_tag="ACHBV5_001812"
     CDS             3829..4173
                     /locus_tag="ACHBV5_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFM9967563.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            4183..5595
                     /gene="lacG"
                     /locus_tag="ACHBV5_001813"
     CDS             4183..5595
                     /gene="lacG"
                     /locus_tag="ACHBV5_001813"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFM9967564.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVQYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            5664..7343
                     /locus_tag="ACHBV5_001814"
     CDS             5664..7343
                     /locus_tag="ACHBV5_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFM9967565.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSVMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            complement(7468..8907)
                     /locus_tag="ACHBV5_001815"
     CDS             complement(7468..8907)
                     /locus_tag="ACHBV5_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFM9967566.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMAFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSLDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(8911..10260)
                     /gene="trkA"
                     /locus_tag="ACHBV5_001816"
     CDS             complement(8911..10260)
                     /gene="trkA"
                     /locus_tag="ACHBV5_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HFM9967567.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            10448..11296
                     /locus_tag="ACHBV5_001817"
     CDS             10448..11296
                     /locus_tag="ACHBV5_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HFM9967568.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            11311..11859
                     /locus_tag="ACHBV5_001818"
     CDS             11311..11859
                     /locus_tag="ACHBV5_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HFM9967569.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
BASE COUNT         3642 a         1943 c         2558 g         3782 t
ORIGIN      
        1 agatacctaa gacgtttatt tcaatacctc caacaacaga tgggatatta tctgtaatag
       61 aaatagtttt tctacgtctt ccagatccgg aaaactcgct aaattcatca ccagtttcgt
      121 atatgaggga ttgttcgctt agctctttta tgatgttagt cgttgttgct ggagtaagtc
      181 ctgtttcatt aacaatatct gtacgggatg ttgctggatt tcgatataga aattccagta
      241 tagtggctct attttgtaaa aaggctgatt gttttgtaat catttgtttc ctcctttggt
      301 ttattttata ttaaacataa gaaaaaatca attaaaatta ttattctata caaagaaaaa
      361 aatattgtaa aaacagtaaa aaatatattg acaacgcttt ctgttagtgg tatatttaat
      421 ttataaaaaa taaaaaaagg agttccggtg atgaacaata ttttaacgtt tttagaaacg
      481 aaagtcgctc cgtttggtga aaaagttggc aatcaacggc atttgaaagc tattcgtgaa
      541 ggatttatga tggcaatgcc tttgatttta gtcggctctt tatttcttat tctaatcagt
      601 tggcctcaag aggcttttac aaattggctg aatagtgttg gattgctaag tatcttgaca
      661 actatgaatc agtcaacagt agcgattatc tccttggtcg cttgtttcgg tattgcctac
      721 aggttgtcgg aaggatatgg tacagatggt ccgtctgcag ggatcatagc cttatccagt
      781 tttgtattga tggcccctcg tttttcaagt atggtttatg ataaaaatgg ggagcaggtc
      841 aagcagttat ttggaggtgc aataccattt tctagcctga atgcgtcttc tttgtttatg
      901 gcgattacca ttggattggt tacagcggag atttatcgta tttttatcca acgcggaatt
      961 acgataaaaa tgccaaatgg tgtcccagat gtggtcagta aatcattttc agctctttta
     1021 cctggtttta ctacttttgt tttgtgggct ttggtcttaa aaggtctgga agcagcagga
     1081 gttgcaggag gtctcaacgg acttttaggt gcaattgttg gaacgccgct taagttaatt
     1141 gcaggaacac ttccaggtat gattttatgt gttattgtaa actcattctt ttggttctgt
     1201 ggagttaatg ggggacaagt tttaaatgct tttgtagacc cagtttggtt acaatttact
     1261 acagaaaacc aagaagctgt ggctgcagga caaaccctac aacacattat tacattaccg
     1321 tttaaagatt tatttgtatt tattggtggc ggtggagcga ctattggtct tgcgatttgt
     1381 ctcttcctat ttagtaagag tcgtgctaat aaaacattag gtaagctagc tattataccg
     1441 tctatcttta atatcaatac agctattcta tttacgtttc caacggtttt aaatcctatt
     1501 atgctgattc cgtttattgc tactcctaca atcaatgcct tgattaccta tgtatcaatg
     1561 gctgtaggct tagtacccta tacaacaggt gtaatccttc cgtggacaat gccacctatc
     1621 ataggaggct tccttgcgac aggggctagt tggcgaggag ctctattaca agttgttttg
     1681 attttggttt ctgtagcaat ttattatcca ttcttcaaaa ttgcagataa acgcaatctt
     1741 gaaaaagaaa aagctactgt tggagggaaa taagatggtt atcagagtat ttgatcaaca
     1801 gaaaaatact tattctagct ttgccttaga ggaattaaga tactatatga atcaggtatt
     1861 taataccgat atagaacttg tcgaggagaa ggaagcggat atttttgtag gattagtcaa
     1921 tgaagaggat ggaaaagacc atattttcat ctcattaaac aaaggtaagg ggagaattga
     1981 gtccaataca attgtaggtt tacttattgg aatttaccga atgtttcatg aatttggtgt
     2041 tgtgtatact agaccagggc gcggacatga ctttattcca gagttaagat ttgaagattt
     2101 tttagataaa gagctatcta tagatgaaac agcaagttac tatcataggg gagtatgtat
     2161 agagggagca gattcatttg aaaatatact agatttcatt gattggctac ctaagattgg
     2221 gatgaacagt tttttcattc agtttgaaaa tccctattct tttttgaaac gttggtatga
     2281 acatgagttt aatccatacc taaataaaga aaaattctca aatgaattag tacaagaatt
     2341 gagtgatagg ttggataaag aattgcaaaa aagaggtctt attcatcatc gtgttggtca
     2401 tggatggaca ggtgaggttt taggttactc ttcaaaattt ggctgggaat caggtcttag
     2461 tatttcagag gagaagaaac cctatgtcgc tgaaataaac gggaaacgag aattgtttaa
     2521 tacggctccg attttaacca gcctggattt ttcaaatcca gatgtagctg ataagatggt
     2581 agaaattatt aaggattatg ccaagaaaag acctgatgtt aactacttac atgtatggtt
     2641 gtcggatgct cgtaataata tttgtgaatg cgaaaactgt agacaagaat tggtttcgga
     2701 tcagtatatt cgtattctca atcaattgga tagggcttta acgagtgagg gattagatac
     2761 aaagatttgt ttcctacttt accatgagtt gttatgggcg cctcagaaag aaaaattaga
     2821 taatcctgaa cgctttacca tgatgtttgc accgattaca agaacatttg aaatgagtta
     2881 tgcagatgta gattttgaca attccatacc tacgcctaaa ccttatctgc gtaataaaat
     2941 tatacttccg aattctcttg aagaaaattt atcttatctt tttgagtggc aaaaaacatt
     3001 taaaggagat agtttcgtat atgactatcc tttagggcgt gctcattatg gcgatttagg
     3061 ctatatgaaa attagtcaaa ctatttacaa agatgtatct tatctttcaa acctacattt
     3121 gaacgggtac atttcgtgtc aagaattacg tgccggattc cctcataatt ttcctaatta
     3181 tgttatgggg caaatgctct ggaagaagac aagaagttat gaagaattga ttgaagaata
     3241 cttttctgct ttgtatgggt caaattggca gtctgttgtt gaatatttag aaaaattatc
     3301 tagttattcc tcatgtgatt attttaatgc aattggcagc cgtcaaaatg atgttttagc
     3361 gaatcattat tatatagctt acaatctagc tgataatttt ttaccaatta ttgaggaaaa
     3421 tatttctaag ttattaaata gtcaaaagga tgaatggaaa cagctcagtt atcatcgtga
     3481 atatgttgtt aagatggcga aggctttata tcttcaagca actggaaaaa caaggcaagc
     3541 tcaagatgaa tggagaaatg ttttgaatta tatccgtggt cacgaattgc tattccaatc
     3601 taatttggat gtttatcgtg taattgaagt agcaaaaaat tacgctggtt tccacttata
     3661 aattataagt atagaaaatg aactaaggta ttcagagaag attgatccta aatattatga
     3721 aatttaagga tttttaagat atttagggtc aactttctat ttgtatcgta gcgaagtcat
     3781 tttaataatg atgtgtaaaa gatgtatcaa gattgaggag gaagaaagat gaaatcaaaa
     3841 gaagaaataa atatgcttgg ttttacaatt gtcgcttacg caggagatgc aaggtcagat
     3901 ttgatggatg ctttggcgtt tgcgagagat ggatattttg aacaggcaag agaattggtt
     3961 gagtctgcaa acgactcaat agtgtctgcc catcgagaac agactaattt attagcggag
     4021 gaggcatctg gagataattt tgaagtgagt tttatcatga ttcatggtca agatactttg
     4081 atgacaacga tgctattgta tgatcaggta aagtttttta ttgatgaata tgaacgaatt
     4141 cgaaagattg aagaacatat tggtttgcaa tgaggattag tcatggaaaa tttacaggtt
     4201 aaagccttac cgaaggagtt tttattagga gctgctaccg ctgcttatca agtagagggt
     4261 gcaactaggg tagatggcaa aggaataaat atgtgggatg tttatttgca agaaaatagt
     4321 ccgttcttac cagatccagc tagtgatttt tattatcgtt acgaagaaga tatagccttg
     4381 gcggcagaac atggtttgca ggctttgcgt ttatctattt cttgggttcg catatttcct
     4441 gatatagatg gggagccgaa tatattggct gttcagtatt accatagagt ctttcagtcc
     4501 tgcttaaaac ataatgtgat tccgtttgtt tctttacatc attttgattc gcctcagaaa
     4561 atgttagaaa caggggattg gttgaataga gagaatattg atcgtttcat acgatatgct
     4621 cgcttttgtt tccaagaatt tacagaagtc aagcattggt ttacaatcaa tgaactgatg
     4681 tctcttgctg caggtcaata tataggaggt cagtttcctc cgaatcatca ttttcaatta
     4741 tctgaagcaa ttcaagcgaa tcataatatg ttgttggcgc atgctcttgc agtcctcgaa
     4801 tttcatcaat tagggattga gggaaaggta ggttgtattc atgctttaaa gccaggctat
     4861 cctattgatg ggcaaaaaga aaatattttg gcagctaaac ggtatgatgt ttataataat
     4921 aaatttctat tagatggaac ttttttgggc tactacagtg atgacacgct ttttcactta
     4981 aatcaaatat tggaagctaa taattctagc tttattattg aagatggtga tttagaaatt
     5041 atgaaaagag ctgcacctct taatacgatg tttgggatga attattatcg ttcagaattt
     5101 attcgtgaat acaaaggtga aaatagacaa gaatttaatt caacaggaat aaaaggacag
     5161 tcctctttta aattaaatgc tctaggtgaa tttgtaaaaa agcctggtat tccgacaaca
     5221 gattgggatt ggaatattta tcctcaaggc ttatttgata tgttacttcg tatcaaagaa
     5281 gaatatcctc aacatcctgt catttattta actgaaaatg gtacagccct taaagaggtt
     5341 aagccagagg gcgagaatga tattattgat gacagtaaga gaatccgtta tattgagcaa
     5401 catttacaca aagttttaga ggctcgagat aggggagtca atattcaagg atattttata
     5461 tggtctttgc aagatcaatt ttcttgggcg aatggctaca ataagcgata tggtcttttc
     5521 tttgttgatt atgagacaca gaagcgatat attaagaaaa gtgctctttg ggtaaaaggg
     5581 ctaaaacgga attaaggtta gcgatttgaa tgatgtttaa tatgttttaa atatgaggtt
     5641 gaatttttta taggaggagt tttatggata agctagtcgc tgccattgaa aagcaacaag
     5701 ggaaatttga aaaaatttct actaataatt atatgatggc tattaaagat ggattcattg
     5761 ctactatgcc tttaattatg ttttcaagct ttttgatgat tattattatg attcctaaaa
     5821 atttcggagt agagttaccg agtccagcta ttgcctggat gaggaaagtg tatatgctaa
     5881 ccatgggagt tttgggtgtt attgtttcag ggacagttgc aaagtcattg gctggaaatg
     5941 ttaatagaaa aatgcctcct ggaaaggtaa taaatgatac ttctgtaatg ttggcagcca
     6001 tatgtagtta tctggtatta actgtaacgc ttgtagttga tgagaagacg ggatctacaa
     6061 gtttgtcgac aaactattta ggatctcaag gattgataac ttcgtttgtc agtgccttta
     6121 ttactgtaaa tgtttaccga ttctgtatta agcgagacat tactattcat ttacctaagg
     6181 aagttcctgg ggctatatca caagctttta gagatatttt tcctttttct tttgttttac
     6241 ttattagtgg tttgttagat attgtatctc ggtttagttt agatgttcct tttgcccaag
     6301 tatttcaaca actattgact cctattttta agggggcaga atcatatcct gctatgatgt
     6361 tgatttggtt tatgtgcgct ttgctttggt ttgttggaat tcatggacca tctattgtct
     6421 tacctgctgt tacagcttta caactgagca atatggaaga gaatgctcaa cttcttgcaa
     6481 atgggcagtt tccttatcat tctttaacgc ctaatttcgg aaattatatc gctgctatcg
     6541 gaggaacggg ggctaccttt gttgtaccat ttattttgat tttctttatg cggtctaaac
     6601 aattaaaatc ggtaggtaaa gctacaatta ctcctgtttt atttgcggtg aatgaacctc
     6661 ttctatttgg tatgccagtt attttgaatc cctatctttt tgtacctttt ttgatgactc
     6721 caccagtgaa tgtatttcta ggaaaggtct ttattgattt ctttggaatg aatggatttt
     6781 atatccagtt accttgggcc tttcctggtc ccttgggatt gttaattgga acgaattttc
     6841 aatctatctc ctttgtattt ttatctttga ttttagttgt cgacatattg atttatttgc
     6901 cattctgtag agcgtatgat agacagttac tgatgaaaga agatgttgca agctcaaatg
     6961 atattatttt agaggaggag acaagtgaaa taatgcctgg tgagttagat gaaataaaaa
     7021 gtaaggagtt gaaagtactg gttctttgtg cagggtctgg aacaagtgcg caattagcca
     7081 atgcaattaa cgagggcgct caattagcag aagttagagt gattgcgaat tcaggagcgt
     7141 acggagctca ttatgatatt atgggtgttt atgatttaat tattctggct ccacaagttc
     7201 ggagttatta tagagagatg aaggtggatg cagaaagatt aggtattcag atagttgcta
     7261 ccagaggaat ggaatatatt catttaacaa agaatccaag taaagcctta caatttgtat
     7321 tggagcatta ccaagctgtg tagtaagttt ttccatcttt tatttgagta aggactttgc
     7381 ttacagacag gcttggattt aaaaacgttc ccccttttta atataaaaat ccctctttca
     7441 caattgtaaa aagagggatt ttgtatttta tctcttagac caagttctct tcataaagag
     7501 aaggaggatt gggtaaatct ccaagcggcc tgcaatcatt gcaaaggaga ggagaatttt
     7561 tgagatagga ctaaagattg agaaactaga agtggttcct agaataggcc cgatattatt
     7621 gaaacagcta aagacagcgc tggtcacgat cagaaaatca ttgctatcta ggctgacaat
     7681 aaagataagg gatagcaaaa tcatagcata gatgacaaag tacttgagaa ttttatgctg
     7741 ggtatcctta tcaatcaccg ttttattcac atggagagtc aaaacacggt ggggagatag
     7801 aatggacaaa atttgatttt tggcaatttt tgaaaggatg aggcctcgaa taatcttgag
     7861 tccacctgca gttgatccag cagaaccacc gattgtcatg aggaagagga ggataaactg
     7921 ggagaagagg ggccagttgg taatatctcc atatccaaaa ccagttgttg taatgatgtt
     7981 ggaaacctgg aagaaggcca tttcaaagct tttggaaaat cctgggtaga ggtagagagt
     8041 attgaggcta atcaagcctg tagaaaccag cacgatgacc aagtaagccc gaagctcttc
     8101 atctccaaag aaggccttaa cccgacggag cataaggtag tagtagagat tgaaatttac
     8161 cccaaaaacc aaaactccta tactaaccag ataggtaatc agtgagctac catagtgggc
     8221 aattccatcg ttatagacgg taaagcctcc agttcccgct gtccccatag caatgacaaa
     8281 actatcgtag agaggcatac cagctagata atagatgatg acaaagaggg agaagagagc
     8341 tagataaagg agatagagaa tctgggcagt gttttttagt ttggatacaa ccttgccaaa
     8401 aacaggacct ggaacctcag ccttcatcac ctctaggtgg ctatttttgg cattgtccat
     8461 aatagcaagt gcaaaaacaa gcactcccat ccctccaatc aagtgggtaa aacttcgcca
     8521 gaagaggagg gaacgactga gaactgaaac gtcgttcaaa atacttgctc cagtagtcgt
     8581 aaagccggaa ctaatctcaa aaaaggcatc aataaggctg gggatttgcc cagaaaagac
     8641 aaaggggaga ccaccaaaga aagaccaaag gatccaacag agggcaacga tcaagactcc
     8701 ctccttggca taaatccgtt gattttttgg cttctgtaaa ctccctgaac cgcctaacaa
     8761 tacgagaatc cctatggtcg aaaagagggc tgtaaagact tggctcgatt cacggtaata
     8821 gacagcgata gccacaggaa ccaagaggag aacagcttca atcaaaagta actttgaaag
     8881 gaggtaacga atcatacttt tattcatttc ttacctcgca atcaagtcat aaatcttggt
     8941 gatgtttggc aacaaggttg ttactaggag cttgtctcca acttccaaca tatcctcccc
     9001 agttgggaaa atagtcttgc cctttcgaat aatggctgca ataagaaccc cttttttcaa
     9061 tttcagttga gaaagaggtt tggcagtcat tttattggct tccttgatat ggaattgcag
     9121 ggtttcaatt tggccattgg ctagatggtg catggcttga aggtctgaat actgggcatt
     9181 aactcgacca cgaataaagt gcataatcgt atctacagcg atgcttttag gtgtgatgat
     9241 acttgaaaaa tcaggcgcat tgataatctc gaggagactg gtacgattga ccttagtaat
     9301 atttttctgt acacctaccc tgtcaaggaa catagatgta atcagatttt cctcatcgac
     9361 tcctgttaga gtcgcaacgg catcatagtg ttgagcactt tcttccagca ggatatcttt
     9421 tgcggttcca tctccttgaa cgatgtagag atttgggaat ttctcgctaa agaagctggc
     9481 gatttcagga ttgatttcaa tgacttttgt atcgatacga ctatctttga gaataccaag
     9541 tagataatag gcaattctac ctgccccaac gatgagaagg ctcttcacgg cgcgtgattt
     9601 aaaataatta tggaagagta tcatatcgac acggttacca gtgacaaaga ttctatcttt
     9661 atcctgtaca gtcatgtcac cgcttggaat gataatttga tgatccctct ctatcgcaca
     9721 gacaatgaca ttaccaaatt ttttacgaaa atcagaaatg ggcatttggc aaagaccgct
     9781 ggtggacttg acgacaaatt ccatgaggct aacgcgtcca ccagcaaagc gttcgacaga
     9841 cagggcgttg gggaagtcaa tgatattcgc gatagcacgg gcagccaaga gctcaggatt
     9901 aacgataaga gaaaaaccga gaatattctt ttccttgaaa taagagttag aatattcagg
     9961 gttccgcacc cgaacgatag tttctttagc tcccattttc ttggctagaa ctgctgcaat
    10021 catgttgact tcatcgtgct cagtcagggc gataaagata tcacaatctt ggacgctggc
    10081 ttgctcaaga atggcaaaat cggccccgtt accaaggata ccaatgatat caaagcgact
    10141 gacaatatga ttgagaacag cttcgtcttg ctcaatcagc aaaacatcat gcttttctgc
    10201 aaccaaggag cgacagaggg caaaaccaac ttttccccct ccgacaagga taattttcat
    10261 aataaaacct actttttcat gatgtaacta tcataccctt tttcaagaaa aaatgcacct
    10321 actagctaat aacaagagct tttagtgaaa attcgctata aggtaaaact ataccctaac
    10381 caattgaaat agctattagc gactttctct gaaatatggt atgataaagg atatacaagg
    10441 agataaaatg aataataatt tactggtatt acaatcagac tttggtctgg ttgatggtgc
    10501 ggtatcggct atgattggag tggctttaga agagtctcca accttaaaaa tccatcactt
    10561 gacgcacgat atcacgcctt ataatatttt tgaggggagc tatcgtctct ttcagacggt
    10621 ggattactgg cctgagggaa cgacgtttgt atcggttgtc gatccaggtg tcggttcgaa
    10681 acgtaagagt gtagttgcca agactgcaaa aaatcaatac attgtcacgc cagataatgg
    10741 gacgctttcc tttatcaaga aacacgttgg cattgtagcc attcgtgaga tttctgaggt
    10801 ggccaatagg cgtcaaaaca cagagcattc ttataccttc cacggtcgtg atgtctatgc
    10861 ctatactggt gctaaactgg ccagtggtca cattactttt gaggaagtag ggccagagct
    10921 cagtgtggaa cagattgtag agcttccagt cgtagcgacc atcatagaag atcatctggt
    10981 gaagggagcc attgatattc tggatgtgcg tttcggttcg ctttggacct ctatcacacg
    11041 ggaagaattt tacaagctgg aaccagaatt tggtgatcgt tttgaagtga ccatctatca
    11101 tgctgatatg ctggtctatc aaaatcaggt tgtctatggc aaatcatttg cagatgtgag
    11161 aattgggcaa cccatccttt acatcaactc tctctatcgt ttaggtttgg ctatcaacca
    11221 aggttccttt gccaaggcct ataatgtagg tgtcggttca tcttggacca ttgaaataaa
    11281 gaaaatagaa ggataaaata ggagaatagt atggaaatta aatttacaat taaacaagtt
    11341 gttgctgtcg gaattggcgc tgccctcttt gtcgtcatcg ggatgatcaa cattccaacc
    11401 cctgttccaa atacaagcat ccagcttcag tatgcggtac aagcgctact ttctattatt
    11461 tttggaccga ttatcggttt gcttgtcggg ttgattggtc atgcaatcaa ggactctctt
    11521 gctggttatg gtctatggtg gacttggatt atcgctagcg gactctttgg tttagttgtg
    11581 ggacttttta gaaagtacgt tcgcgtgatc aatggtgttt ttgactggaa agatattctt
    11641 atttttaacc tcattcaact acttgcaaat gcccttgttt ggggtgtctt ggcaccactt
    11701 ggagatgttg tgatttatca agaagcggca gaaaaagtat ttgcacaagg gattgttgcg
    11761 ggaattgcca atggtgtatc tgtagctatt gcaggaactc ttctcttact tgcctatgca
    11821 ggaacccaaa ctcgtgcagg aagtttgaaa aaggactaat actcaatgaa aatcaaagag
    11881 caaactagga agttagccgc aggttgctca aaacagtgtt ttgaa
//
LOCUS       DAYYYC010000059        11915 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.059, whole genome shotgun sequence.
ACCESSION   DAYYYC010000059 DAYYYC010000000
VERSION     DAYYYC010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11915
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.059"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..208
                     /locus_tag="ACHBV5_001819"
     CDS             <1..208
                     /locus_tag="ACHBV5_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM9967570.1"
                     /translation="RKSSKLKPLTVEDKAYNHALSKDRSKVENIFAKVKTFKMISTTY
                     RNHRKRFGLRMNLSAGIINHELGF"
     gene            400..2691
                     /gene="pcrA"
                     /locus_tag="ACHBV5_001820"
     CDS             400..2691
                     /gene="pcrA"
                     /locus_tag="ACHBV5_001820"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFM9967571.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2734..3414
                     /gene="radC"
                     /locus_tag="ACHBV5_001821"
     CDS             2734..3414
                     /gene="radC"
                     /locus_tag="ACHBV5_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFM9967572.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3411..4100)
                     /locus_tag="ACHBV5_001822"
     CDS             complement(3411..4100)
                     /locus_tag="ACHBV5_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFM9967573.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDSGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELTLIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4118..4759)
                     /locus_tag="ACHBV5_001823"
     CDS             complement(4118..4759)
                     /locus_tag="ACHBV5_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFM9967574.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4842..5057)
                     /locus_tag="ACHBV5_001824"
     CDS             complement(4842..5057)
                     /locus_tag="ACHBV5_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HFM9967575.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5065..5412)
                     /locus_tag="ACHBV5_001825"
     CDS             complement(5065..5412)
                     /locus_tag="ACHBV5_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFM9967576.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5417..6532)
                     /locus_tag="ACHBV5_001826"
     CDS             complement(5417..6532)
                     /locus_tag="ACHBV5_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFM9967577.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6542..7501)
                     /locus_tag="ACHBV5_001827"
     CDS             complement(6542..7501)
                     /locus_tag="ACHBV5_001827"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFM9967578.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGAPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7614..8183)
                     /locus_tag="ACHBV5_001828"
     CDS             complement(7614..8183)
                     /locus_tag="ACHBV5_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFM9967579.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8311..8982
                     /locus_tag="ACHBV5_001829"
     CDS             8311..8982
                     /locus_tag="ACHBV5_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFM9967580.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8966..9784
                     /locus_tag="ACHBV5_001830"
     CDS             8966..9784
                     /locus_tag="ACHBV5_001830"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFM9967581.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9781..10677
                     /locus_tag="ACHBV5_001831"
     CDS             9781..10677
                     /locus_tag="ACHBV5_001831"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFM9967582.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHLLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10721..11695
                     /gene="pta"
                     /locus_tag="ACHBV5_001832"
     CDS             10721..11695
                     /gene="pta"
                     /locus_tag="ACHBV5_001832"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFM9967583.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         3484 a         2285 c         2566 g         3580 t
ORIGIN      
        1 acgtaaatcc agcaaactca agccgctaac agttgaagat aaagcctata accatgcgct
       61 atccaaggat agaagcaagg ttgagaacat ctttgccaaa gtaaaaacgt ttaaaatgat
      121 ttcaacaact tatcgaaatc atcgtaaacg tttcggatta cgaatgaatt tgagtgctgg
      181 tattatcaat catgaactag gattctagtt ttgcaggaag tctattgagg tattgagcta
      241 gtttatgaaa aaattgggtg aaaaagtcga gtgttttaga aacccacagt gtagtattct
      301 agtttcaatc cactatattt tgctactccc cgtaaagttt ctattttccc tgatttctga
      361 tataatagaa atattgactt caagagtaag gaagagaaga tgaacgcatt attaaatgga
      421 atgaatgacc gtcaggctga ggcggtgcaa acgacagaag gtcccttgct aatcatggca
      481 ggggctggtt ctggaaagac tcgtgttttg acccaccgta tcgcttattt gattgatgaa
      541 aagctggtca atccttggaa tatcttggcc attaccttta ccaacaaggc tgcgcgtgag
      601 atgaaagagc gtgcttatag cctcaatcca gcgactcagg actgtctgat tgcgaccttc
      661 cactccatgt gtgtgcgtat tttgcgtcgc gatgcggacc atattggcta caatcgtaat
      721 tttacaattg tggatcctgg tgaacagcga acgctcatga aacgtattct caaacagttg
      781 aacttggatc ctaaaaaatg gaatgaacga actattttgg ggaccatttc caatgctaag
      841 aatgatttga ttgatgatgt tgcttatgct gcccaagctg gcgatatgta tacgcaaatt
      901 gtggcccagt gttatacagc ctatcaaaaa gaacttcgtc agtctgaatc cgttgacttt
      961 gatgatttga ttatgctgac cttgcgtctc tttgatcaaa atcctgatgt tttgacctac
     1021 taccagcaaa aattccaata catccacgtt gatgagtacc aagataccaa ccacgctcag
     1081 taccaattgg tcaaactctt ggcttcccgt tttaaaaata tctgtgtggt tggggatgcg
     1141 gaccagtcta tctacggttg gcgtggtgct gatatgcaga atatcttgga ctttgaaaag
     1201 gattacccca aagccaaggt tgttttgttg gaggaaaatt accgctcaac caaaaccatt
     1261 ctccaagcgg ccaacgaggt tattaaaaat aataaaaatc gccgtcctaa aaatctctgg
     1321 actcaaaacg ctgatgggga gcaaatcgtt tactatcgtg ccgatgatga gctggatgag
     1381 gctgtatttg tagccagaac catcgatgaa cttagtcgca gtcaaaactt ccttcataag
     1441 gattttgcag ttctctatcg gactaatgcc cagtcccgta caattgagga agccctgctc
     1501 aagtctaaca ttccttatac catggttggc ggaaccaaat tctacagccg taaggaaatt
     1561 cgcgatatta ttgcttatct caaccttatt gctaatttga gtgacaatat tagttttgag
     1621 cgtattatca acgagcctaa acgtggaatt ggtctaggta cagttgagaa aatccgtgat
     1681 tttgcaaatt tgcaaaatat gtctatgctg gatgcttctg ctaatattat gttgtctggt
     1741 atcaagggta aggcagccca atctatctgg gattttgcca atatgatgct tgatttgcgg
     1801 gagcagctag accacttaag cattacagag ttggttgagt ccgtcctaga aaaaacaggt
     1861 tatgtcgata ttcttaacgc ccaagcgact ctagaaagca aggcacgggt tgaaaatatc
     1921 gaagagtttc tttctgttac gaagaacttt gatgacacca ctgatgtgac agaagaggaa
     1981 actggtctgg acaaactgag tcgtttctta aatgacttgg ctttgattgc cgacacagat
     2041 tcaggtagtc aggagacatc agaagtgacc ttgatgaccc tgcatgctgc caaaggtctc
     2101 gaatttccag ttgtcttttt gattgggatg gaagaaaatg tctttccact tagtcgtgcg
     2161 actgaagatc cagatgaatt agaagaagag cgccgtctag cctatgtagg tatcacgcgt
     2221 gcagagaaaa ttctctatct gaccaatgcc aactcacgct tgctttttgg tcgtaccaat
     2281 tataaccgtc cgactcgttt tattaacgaa atcagttcag acttgcttga gtatcaaggt
     2341 ctggctcgtc ctgcaaatac aagctttaag gcatcatata gcagtggtag tatttccttt
     2401 ggtcaaggta tgagtttggc tcaggctctt caagaccgta aacgcggtgc tgccccaaaa
     2461 tcaatccagt caagcggtct tccatttggt caatttacag ctggcgcaaa atcagcatct
     2521 agcgaggcaa attggtccat tggtgacatt gctctccaca agaaatgggg agagggaact
     2581 gttctggaag tttcaggtag cggtgctagg caggaattga aaatcaattt cccagaagta
     2641 ggtttgaaaa aacttttagc cagtgtggct ccaattgaga aaaaaatcta attttccatc
     2701 cttctcacga ataataaagt gaggaggatt tttatgtaca gtatttcatt ccaagaagat
     2761 tcactattac caagagaaag gctggccaag gaaggagttg aagcgcttag taaccaagag
     2821 ttgctagcta ttttactcag gacaggaaca cgtcaagcta gcgtttttga aattgcccaa
     2881 aaagtcttga acaatctttc aagcctaacg gatttgaaaa aaatgaccct gcaggaattg
     2941 cagagtttgt ctggtattgg gcgtgttaag gccatagaat tacaagctat gattgaactg
     3001 gggcatcgta ttcacaaaca cgagactctt gaaatggaaa gtattctcag cagtcaaaag
     3061 ttggccaaga agatgcagca ggaattaggg gataaaaaac aagagcacct ggtggcactc
     3121 tatctcaata ctcaaaatca aatcatccat cagcagacca tttttatcgg ttctgtaact
     3181 cgtagtatcg ctgaaccgcg agagattctg cactatgcaa tcaagcatat ggcgacttct
     3241 cttatcttgg tccacaatca tccttcagga gcggtagcgc ctagccaaaa tgatgatcat
     3301 gtcactaaac ttgttaaaga agcctgcgaa ttgatgggga ttgttctctt ggaccatttg
     3361 attgtctctc attctaatta ctttagttat cgtgaaaaga cagatttaat ctaaagttca
     3421 ttaacgacat agtcaaagag ttttttatct ttgggacgat tttcaaaaag aagttctgga
     3481 tgccattgga caccgagaaa ggcgacatca tccgtactca tgacagcctc aatgatacca
     3541 tctttaggat catgagccac aacttttaaa tttggtgcta agtccttgat gctctggtgg
     3601 tggaaggagt tgatatgaga gatttctcca tagatttctt ggagaacggt atctggttct
     3661 gttaccaagc gttgagttgt gtactcaaca gaagaatcct gccaatggtc ttcgatatct
     3721 tggtacaaag ttccacccat ggcaacgtta aagagttggg taccacggca gacagagaaa
     3781 atgggctttt tctgtttaat agcttccttg atgagggtca gttcgaagat atctctttga
     3841 aggtgatagt catcgctatc aatggttttg ggttcgccat aaaattttgg atcgacattt
     3901 tgcccacctg tcaagatgag cttgtcaatc aaactgatat agtggcaggc catttcttga
     3961 tcaccaatcg gtaggatgat gggaatccct ccagaatctt taacgccttc aacaaagcct
     4021 tttgctgcgt agctcatcat gatgtcatca tctggatgag ctttttcgtt tcctgtaatc
     4081 ccaataactg gttttttcat aaaatgattt tcgctttcta atcctctttt cgcatgaagt
     4141 agaggagggt ttggagttca cttgtcaaat cgacatactg aacgaccacg tcttttggta
     4201 aatgcagatg gactggtgaa aaactgagaa ttcctttcac accagcatca accaagagat
     4261 tagcaacctc ttgtgacttg acgctgggaa cagttaggat agcagtcttc acatcagcat
     4321 ccttgatttt atccttgatc tgagaaatcc cgtaaatggg aatcccgtca ggagtttggg
     4381 taccgacttc aggatggtcg tctaggtcaa aggccatgat aatcttcatc ttgttacgtt
     4441 cgtggaagcg gtagtggaga agggcatggc ccatatttcc aataccaacc agcatgacat
     4501 tggtaataga gttgtcattg agcaaatcgg caaaaaatgt cattagtttt ttgacatcat
     4561 agccaaaacc acgacgacca agttcaccaa aataggaaaa atcacgacgt acggtcgctg
     4621 aatcaatacc gatagcctct gcaatttgct tagagttggc acgttcaatc ttttctgcat
     4681 gaaatctctt aaaaattcga tagtagagag agagtctttt tgctgtagct tttggaatag
     4741 caaactgttt atctttcaca aaatcacaac ctttctattc ttctatttta tagaaacatt
     4801 gtgaaaaaat caacaaaaat aagaaaaaac taagaaaaat cttagttttg atgtaaaaaa
     4861 tctgcatgag atagaaaacg gtagaggtct ccgaccagac cctgataaac tttttggccc
     4921 ctaaaagtca gagaagtcac ataaagtgta tctggtaagg ttacacatcc tgacaaagtc
     4981 aacatgagag cctcatgatc ctcatacttg agagtacgct ctacatgata gcagtcctta
     5041 taggtcagtt caaacatttt ggctctatct ttccgatttt gtaaagacac cacgttctac
     5101 caagctatcc atgaggaagt agaatttttc ctgatgaata tggtggtctt ctgatttgaa
     5161 aatatcaact agacgaaggc caaacttgtc agtgatattg attttagccc ctgtaagttc
     5221 cttgttaatg atgattttga gttggaagcc ttcaccgctg tttggcactt tttccaaaag
     5281 gcgagtcagt tcatagttac caaccttagt ttcaaaaaag gtgttatctt tgagggtgaa
     5341 ttttttaaca gaagggctaa gagtgtaatc gtaacgacaa ttttttaact gaatgatttt
     5401 ttcaaatgcc atatggctaa cctccgataa tttcttttaa ggtttttgcg agggtttgta
     5461 ggtcttcaac ggtattttgt ggcgacaaac tgatgcgaag ggattccttc aagcgttctg
     5521 aatttgcgcc atacatggct tcaagaacat ggctggattg gacaacgcct gcagtacagg
     5581 ctgagccagt agagattgaa attccagcta aatctagccg aaggagtaag aggtcatttt
     5641 tctgaccagg aaatccaata ttgagaacat aagggagatg atgttttcct ctattcaagt
     5701 aatactgaat gccctccagc tctgccagaa aggcagtttc tagattttgt acatgttgaa
     5761 aatgttcttc ttgtttttct aggtcttctt ttagggctgc aaccatgcct acgatagcag
     5821 gcagattttc agttcctgca cgttttttct gttcctggtc tccgccatgt agataggaat
     5881 caaagtccat gctagatgcg tagagaaaac cgattccctt aggaccatgg aatttgtggg
     5941 cagaagcagt gagaaaatca atgcccaatt cttctgaatg aattgggatt ttaccaatag
     6001 cctgaactgc atcaacatga taggcagcag ggtgttgctt gagtatttgg ccaatttcag
     6061 cgatgggcag taggtttcct gtctcattat tggcaaacat ggtagaaacc aaaatcgtat
     6121 cgtcacgtaa agccttttga atttgctggg ctgtgatttc ttgattttct ggctggataa
     6181 tggttgcttc aaacccaaag tgttgaacca agtaatcaat tgtttcaagg acagcatggt
     6241 gctcgatggc agttgtgatg atatgttttc cttgttcttg gtgacgaaga cagtagccaa
     6301 tgatggtagt attattgcct tcagtcccac cagaagtgaa aaagatatgt tgaggttttg
     6361 tccttagtaa ctgggctagt tcctgacggg cttctcgcaa gagtttgcca gcttgacgac
     6421 catgaccatg aatactagaa ggatttccgt gggtttcttg cataaccttg gtcatagctg
     6481 aaatagcaac tgctgacata ggagtcgttg cagcattgtc caaataaatc aaagaatcac
     6541 cttatttctt tttattgtag gcaaagagtg ggctgactgg ttttctttcg tgaatacgga
     6601 cgatagcatc accaattaac tcactagcag tgatgtagca tacattttta ggagtttttt
     6661 cttttgttgc tactgaatca gtcacaagaa tttctttaat attagtattg tcaagaagct
     6721 cagcagctcc ctcgacgaag agaccgtggc tagaaacagc ataaatttct gtagctcctt
     6781 cacgttcaac gattttagaa gcttcagaga aggtacgtcc tgtatttaaa atatcatcaa
     6841 tcaagatagc tttcttacct tcaacatcac caataatata accttcgtta cgagttgcat
     6901 cgtcttgagg gtagtcgata atggcgatag gagcatcaag atattcagcc aggctacgcg
     6961 cacgtttgac acctgaattt ttagggctaa cgacaacaac atctgaacca agcaatcctt
     7021 tatcgcagta atgttttgcg aataggggaa cagtgaaaag attatccact ggaatatcaa
     7081 agaaaccttg aacctgaacg gcatgcaaat caagagtcag gatacgatca actccagcct
     7141 taaccagcat attggcaact agttttgctg taagtggctc acgaggacaa gcaatgcggt
     7201 cttgacgtgc atagccaaaa tatggaagga caacgttgat actgtgggca cttgcacgca
     7261 cacaagcatc gaccatgatt aacaattcca ttaggtggtt gttgacaggg aaacttgttg
     7321 attggatgat gtaaacatca taaccacgga cactttcttc gatatttact tggatttctc
     7381 cgtctgaaaa ttgacgtgat gatagttttc caagtggggc accaacagct tgggcaattt
     7441 tttgtgcaat ctcttggtta gagttgagtg cgaaaagttt catgtttttt ctatctgaca
     7501 ttatagaccg tcctctgtaa actttataaa tcctagttat atttacctta catatatgaa
     7561 ctgggatttg tgtattttta tcttttctat tttaccaaaa aatggagatt atttcagcta
     7621 tttttcatac ttttgacaaa tcgaaccaat tttgaaggag ctttttggta ggaaatctga
     7681 tttttctcta aaaattgtcg gaaatcctgt ttgccttgct catgattttc cacttcaagc
     7741 tccaattcgt aatctgttat atcaaagtat cggctctgat ccagtgccat gagaccaata
     7801 gctgttttca tttcatagcg aagcgttgtt agacaaccaa gaacctgcca gttcttactt
     7861 tggataccat gtttcgccaa ttcatccagt actagccctt gaggaagttc ttccttactc
     7921 agatagttct cagcatcttt tagttgcaat ttttggttgt attccatgtt tccaacactc
     7981 tgcgggactt tgagtgtcaa ctcagcccag tcttcaaagg ttcgaatgcg catagcgact
     8041 ttcttttctc gcagttcaaa atcaggcgtg tcgatgtagt aatttgtttg aagaacagga
     8101 gtgacacctg tgaactggtc ttttagacga ttgtattcat cttttttcaa tagtgttttc
     8161 aattcaattt ctaaatgttt catttttctt accttttttt atcgttgaaa gcggatttat
     8221 ggtataataa gcattgtatt tattgtatat gaatctggag aaaaaatcaa agatattttt
     8281 gacggataat atgagaacaa gggagaatat atgaccttag aatgggaaga atttctagat
     8341 ccttacattc aagctgttgg tgagttaaag attaaacttc gtggtattcg taagcaatat
     8401 cgtaagcaaa ataagcattc tccaattgag tttgtgaccg gtcgagtcaa gccaattgag
     8461 agcatcaaag aaaaaatggc tcgtcgtggc attacttatg cgaccttgga acacgatttg
     8521 caggatattg ctggcttacg tgtgatggtt cagtttgtag atgacgtcaa ggaagtagtg
     8581 gatattttgc acaagcgtca ggatatgcga atcatacagg agcgagatta cattactcat
     8641 agaaaagcat caggctatcg ttcctatcat gtggtagtag aatatacggt tgataccatc
     8701 aatggagcta agactatttt ggcagaaatt caaattcgta ctttggccat gaatttctgg
     8761 gcaacgatag aacattctct caactacaag taccaagggg atttcccaga tgagattaag
     8821 aagcgactgg aaattacagc tagaatcgcc catcagttgg atgaagaaat gggtgaaatt
     8881 cgtgatgata tccaagaagc ccaggcactt tttgatcctt tgagtagaaa attaaatgac
     8941 ggtgtaggaa acagtgacga tacagatgaa gaatacaggt aaacgaattg atctgatagc
     9001 caatagaaaa ccgcagagtc aaagggtttt gtatgaattg cgagatcgtt tgaagagaaa
     9061 tcagtttata ctcaatgata ccaatccgga tattgtcatt tccattggcg gggatggtat
     9121 gctcttgtcg gcctttcata agtacgaaaa tcagcttgac aaggtccgct ttatcggtct
     9181 tcatactgga catttgggct tctatacaga ttatcgtgat tttgagttgg acaagctagt
     9241 gactaatttg cagctagata ctggggcaag ggtttcttac cctgttctga atgtgaaggt
     9301 ctttctcgaa aatggtgaag ttaagatttt cagagcactc aacgaagcca gcatccgcag
     9361 gtctgatcga accatggtgg cagatattgt aataaatggt gttccctttg aacgttttcg
     9421 tggagacggg ctaacagttt cgacaccgac tggtagtact gcctataaca agtctcttgg
     9481 cggtgctgtt ttacacccta ccattgaagc tttgcaatta acggagattg ccagccttaa
     9541 taatcgtgtc tatcgaacac tgggctcttc cattattgtg cctaagaagg ataagattga
     9601 acttattcca acaagaaacg attatcatac tatttcggtt gacaatagcg tttattcttt
     9661 ccgtaatatt gagcgtattg agtatcaaat cgaccatcat aagattcact ttgtcgcgac
     9721 tcctagccat accagttttt ggaaccgtgt taaggatgcc tttatcggtg aggtggatga
     9781 atgaggtttg aatttatcgc agatgaacat gtcaaggtta agaccttttt aaaaaagcac
     9841 gaggtttcta agggattgct ggccaagatt aagtttcgag gtggagctat tctggtcaat
     9901 aatcaaccgc aaaatgcaac gtatctattg gacgttggag actacgttac cattgacatt
     9961 cccgctgagg aaggctttga aaccttggag gctattgagc atctattaga tattctctat
    10021 gaggatgatc actttctagt cttgaataaa ccctatggag tggcttctat tcctagtgtc
    10081 aatcactcta ataccattgc caattttatc aagggttact atgtcaagca aaattatgaa
    10141 aatcagcagg ttcacattgt taccagacta gatagggaca cttctggctt gatgctcttt
    10201 gccaagcacg gttatgccca tgcacgatta gacaagcagt tgcagaagaa atctatcgag
    10261 aaacgctact ttgctttggt taagggagat ggacatttgg agccagaagg ggaaattatt
    10321 gctccgattg cgcgtgatga agattccatt attaccagac gagtggctaa aggcggaaag
    10381 tatgcccata cttcatacaa gattgtagct tcttatggaa atattcactt ggtctatatt
    10441 cacctgcaca ctggtcgaac ccatcaaatc cgagtccatt tttctcatat cggttttcct
    10501 ttgctgggag atgatttgta tggtggtagt ctggaagatg gtattcaacg tcaggctctg
    10561 cattgccatt acctatcctt ttatcatcca tttttagagc aagacttgca gttagaaagt
    10621 cccttgccgg atgatttcag taaccttatt acccagttat caactaatac tctataaaaa
    10681 ctgtctcaga gtataattat tatcttaaag gagaaaactc atggaagttt ttgaaagtct
    10741 caaagccaac cttgttggta aaaatgctcg tatcgttctc cctgaagggg aagagcctcg
    10801 tattcttcaa gcaacaaaac gcttagtaaa agaaacagaa gtgattcctg ttttgcttgg
    10861 aaatcctgaa aaaattaaaa tttatcttga aattgaagga atcatggatg gttatgaggt
    10921 catcgaccct caacattatc ctcaatttga agaaatggtt tctgccttgg tggagcgtcg
    10981 caagggcaaa atgactgaag aagatgtacg caaggttttg gttgaagatg tcaactactt
    11041 tggtgtgatg ttggtttact tgggcttggt tgatggaatg gtgtcaggag cgattcactc
    11101 aacagcttca acagttcgtc cagctctaca aatcatcaaa actcgtccaa atgtaactcg
    11161 tacttcagga gccttcctca tggttcgtgg tacggaacgt tacctatttg gagactgtgc
    11221 cattaacatc aatccagatg cagaagcctt ggctgaaatt gccatcaact cagcaatcac
    11281 agctaagatg tttggcatcg aacctaaaat tgccatgttg agctattcta ctaaaggttc
    11341 agggtttggt gaaagcgttg ataaggtcgt tgaagcaact aaaattgctc acgacttgcg
    11401 tcctgacctt gaaatcgatg gtgagttgca atttgatgca gcctttgttc ctgaaactgc
    11461 agctctgaaa gctcctggaa gtacggtagc tggtcaagca aatgtcttca tcttcccagg
    11521 tatcgaggca ggaaatatcg gttacaagat ggctgaacgc ctaggtggct ttgcggctgt
    11581 aggacctgtt ttgcaaggtt taaacaagcc agttaatgat ctttctcgtg gatgtaatgc
    11641 agatgatgtt tacaagttga ccctcatcac agcagctcaa gcagttcatc aatagtgaaa
    11701 actataaagc gatatactat gctatactgt agttatgaaa ctatgtacga aaagcactgc
    11761 cattaattcc tgagaactaa attactgatt ggtgtcaaaa aggaaaactt ccaagcgata
    11821 atatcctgtc tatacacgac ctatagaaat ctgtaatata catgtccgta aaacgataaa
    11881 ttcccttttt gattttaaat gagtatgaaa agaga
//
LOCUS       DAYYYC010000060        11043 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.060, whole genome shotgun sequence.
ACCESSION   DAYYYC010000060 DAYYYC010000000
VERSION     DAYYYC010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11043
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.060"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(1..374)
                     /locus_tag="ACHBV5_001833"
                     /pseudo
     CDS             complement(1..374)
                     /locus_tag="ACHBV5_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            415..720
                     /locus_tag="ACHBV5_001834"
                     /pseudo
     CDS             415..720
                     /locus_tag="ACHBV5_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            852..1796
                     /gene="manA"
                     /locus_tag="ACHBV5_001835"
     CDS             852..1796
                     /gene="manA"
                     /locus_tag="ACHBV5_001835"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFM9967584.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(1836..3171)
                     /locus_tag="ACHBV5_001836"
                     /pseudo
     CDS             complement(1836..3171)
                     /locus_tag="ACHBV5_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3399..4148
                     /locus_tag="ACHBV5_001837"
     CDS             3399..4148
                     /locus_tag="ACHBV5_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFM9967585.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(4168..4623)
                     /locus_tag="ACHBV5_001838"
     CDS             complement(4168..4623)
                     /locus_tag="ACHBV5_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HFM9967586.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4643..5818)
                     /locus_tag="ACHBV5_001839"
     CDS             complement(4643..5818)
                     /locus_tag="ACHBV5_001839"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFM9967587.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5877..6722)
                     /locus_tag="ACHBV5_001840"
     CDS             complement(5877..6722)
                     /locus_tag="ACHBV5_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFM9967588.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            6847..7404
                     /locus_tag="ACHBV5_001841"
     CDS             6847..7404
                     /locus_tag="ACHBV5_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFM9967589.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7423..7890
                     /locus_tag="ACHBV5_001842"
     CDS             7423..7890
                     /locus_tag="ACHBV5_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HFM9967590.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7979..8608
                     /gene="upp"
                     /locus_tag="ACHBV5_001843"
     CDS             7979..8608
                     /gene="upp"
                     /locus_tag="ACHBV5_001843"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFM9967591.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8782..9372
                     /gene="clpP"
                     /locus_tag="ACHBV5_001844"
     CDS             8782..9372
                     /gene="clpP"
                     /locus_tag="ACHBV5_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HFM9967592.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9451..9699
                     /locus_tag="ACHBV5_001845"
     CDS             9451..9699
                     /locus_tag="ACHBV5_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFM9967593.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9800..10960
                     /locus_tag="ACHBV5_001846"
     CDS             9800..10960
                     /locus_tag="ACHBV5_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM9967594.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVIDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGRDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
BASE COUNT         3483 a         2178 c         2345 g         3037 t
ORIGIN      
        1 agccttcaaa tgacgggcaa gaaaggcttt ctcttcctca actgtcatat atgcatggtt
       61 acgaccacca cgtgtttctt gaaggagaga gtcgagtccg aactcctcat attttttaca
      121 ttttgctaaa tcgttgtttg attacagtct aaaagctcta taatctcttt ataagatttg
      181 cccatcagac gaaatataat agattgaaac tagaatagta cacctctact tctaaaacat
      241 tgttagaaat cgatttgtcc tgttcttgtt tcattttact atagaacgat ttgaaggcgt
      301 ttataatatt tagctgtacg agagtctttt aaaagtgttt tgatggtttg gatttcttct
      361 ttagttgatt tcatattact attgtataat gctttttgat tttagtttag tattatcgta
      421 gaaaatggac tcggtgctat ggatacaccg gatgagaatg gttatgtagc agatgactat
      481 cggattactt acttagaggc ccacatcaag gccatgcgag atgccattta ccaagatggg
      541 gttgacttgc ttggttatac gacttggagc tgtatcgatc cggtttcagc tggcacaggg
      601 gaaatgaata agcgctatgg ctttatctat gtagatcgag ataatgtagg aaatgggact
      661 ctcaaacgta gcaagaagaa gtccttctat tggtacatgt catttatagc aatggtgtaa
      721 gcatcgagta gagcacattt gtttactatt tttataaaat cttctccctg ctttataaga
      781 tgtaaaaaag agttcaaatg gaactctttt tttgctataa tgaggggaga aaaatcagac
      841 aggagattaa gatgtcagaa ccattatttt tacaatcagt tatgcaagaa aaaatctggg
      901 gtggtaccaa gttacgtgat gagtttggct acgacatccc aagtgaaaaa gtcggagagt
      961 actgggctat ctcagctcat ctaaatggtg tttctaaagt tgccaatggt cgttacgagg
     1021 gaacagatct tgctactttg tatgcggaac accgtgaatt atttggcaat cgtccagaac
     1081 ctgtatttcc gcttttgacc aagatcctcg atgccaacga ctggctcagt gtccaagttc
     1141 acccagacga tgcttatgga ctcgagcatg aaggcgaact tggaaaaaca gaatgttggt
     1201 acatcattgc agcagatgaa ggttcagaga ttatctacgg tcacaatgcc aagtcaaaag
     1261 aagaactccg ccagcaaatc gaggataaga actgggatgc gctgttgaca aaagtgccag
     1321 ttaaagcagg agatttcttc tatgtaccaa gcggtaccat gcacgctatc ggggcgggta
     1381 tcttgattct tgaaacccag cagtctagcg ataccactta ccgtgtctat gactttgacc
     1441 gtaaggatga caagggcaat ttacgtgaac ttcaccttga aaaatctatc gatgtcttga
     1501 acattggtga acccgcaaat agccgtccag tgacaatcaa agcagatgat ctacgttcca
     1561 ctctccttgt atccaatgat ttcttcgcag tttacaaatg ggaaattact ggaaaagtta
     1621 actttgaaaa gacagctgac tacagcttgt tgagtgtctt ggctggtcaa ggtcagctaa
     1681 ctgttgacgg gaaaaattat ccaattcaaa aaggcagcca ctttatccta ccaagtgatg
     1741 ttgaagcttg gactctggaa gggcaaggtt tggaattgat tgttagccat ccataaaaag
     1801 aaagggcctg agttcactac tcaagtcctt tttgattaca taaattgggc aatgaagacc
     1861 acaatgatga tgattggaat gacgaaacga agaaacgaag aaggaagagc cagacttgga
     1921 acagtccttg tttccatgct ctttcatcga gatggagttc ctccattgca agagcctttt
     1981 taaagatata gcctgtaaaa agtgaaaggt agagagctcc aaatggcatg aggagattgg
     2041 aaaccaagaa gtccatagcg tcaaagaagg tcttaccaaa aatgtgaaca tccgccatga
     2101 caccgtaaga tagggctgaa ggaatgccaa agacaaaggt caaaattcct aaaataacac
     2161 tccatttggc acgtttgctg ttatcctggt tggtgatatt gcccacattg atctccagca
     2221 tcacgacaga agaagtgaca gtcgcaaaga gggagcggac gtagaaaatg gttccaaaag
     2281 gcatcttgtc aaagagttga ggcaagacga taaagagcag gctgggtccc ccttcagact
     2341 ggatattgaa gggggatcga gcttggaaaa tggctagacc tgccatgatg gatatcgaga
     2401 tattcatggc tacgatggag attcctgact ggactagatt ggttttcttg tccaagtaag
     2461 aagcataggt caacatgact gtaaccccta gtgagagggc aaagaaagat tgtcccagag
     2521 catagaggag accagcgcta gtcagttttg aaaagtctgg tttgaggaag taaagaaccc
     2581 cttccatggc atttggcaaa ctgagagagc gactgatgat aaaaacaaag acgataaaga
     2641 gcaggggcat catgactttc gaagctcttt caatcccttt ttgaacccca cgtgatacaa
     2701 tgaagatatt caataggata aaggccgctt gagctcctag ggcaatggct ggatttgaaa
     2761 tgattgaagt aaataactga gcataatcac ccgttccacc aagttggaac aatttcccaa
     2821 actcaatacc tagatagact agaatccatc ctccgataac actgtaaaaa gataagagga
     2881 taaagagggc aaaggcgcca atccaaccga taaagttgta cttgttattc ttgcccagtt
     2941 ttccaaaggt tttgatagcg gaaacgccag cactacggcc aagggcaaac tcagccagca
     3001 ggagagggaa accgattaaa atagtggaaa tgagaaagat tagtaaaaag cctccaccgc
     3061 cattagcagc agtcatgtag ggaaacttcc aaacggaacc aagcccgatg gccagccagc
     3121 agatgctaga ataaaaccaa gtttcgaccc ccattgtgat ttttctgaca tagttaaact
     3181 ctgatctcct ttttcaaaat aagaaaaagc tacttgagtt gtcaaatagc cttctgtttg
     3241 attgatagac ttgactatcc tatcatgttt tctaaggtct gtcaagaaaa tcattttcaa
     3301 gttttcacac ctttctcaaa aaagttaaaa aattttctca aaaacgcttg actctgacct
     3361 aaggggaggg gttatactat cattgtaagg aggaaatcat gtaccatata aaagaagctg
     3421 cgcagctttc aggtgtctct gtcaagaccc tgcatcacta tgacaagata ggactcttgg
     3481 tccccttaaa gtcggaaaac ggctatcgaa cctacagtca agaggatttg gaacgccttc
     3541 aggtcattct ttactacaaa tatctaggtt tttctttaga gaaaatagca gagctgttaa
     3601 aggaagaaag gacagattta ttgccccatt tgactaggca gttggactat ctaactcgcg
     3661 aaaggcaaca tctggatacc ttgatttcca ccttgcaaaa aactattcaa gaacaaaaag
     3721 gagaaagaaa aatgaccatt gaggaaaaat tcacgggatt tagctatcaa gacaatcaaa
     3781 aataccacca agaagcggta gagaaatatg gtcaagaagt catgggacaa gcgctcgaac
     3841 gccaaaaagg tcacgaagac gaggctacgg ccgcctttaa ccaagtcttt caaactttgg
     3901 cacaaaatct tcaagttggt ttacctgcaa cagcaaccga aaaccaggag caagcagcca
     3961 agctcttgca agccattcgc acttatggat ttgactgctc tattgaggta ttcggtcata
     4021 tcggtaaagg ttacgtctat aacccagagt ttaaggaaaa cattgacaag tttggttctg
     4081 gaacagccca gtacacgtca gatgccattg cagcttacgt tcagacaaat gcagaaaaaa
     4141 taggctagga atttcctagc ctatttttta cttcaaatca taaagccagt cgtcaccgtt
     4201 tttgtagtaa aagaattcac tgagatcttc ttctagaaac acacgaagca tatcagacat
     4261 atcatcggtt gcaagtttta gatgagaaag attttcaaag tcctcccacc aaactttccc
     4321 ttcgtctgaa gactggagtt caccagtaaa gtgttctgtc ttgtaaaaaa ggacgacata
     4381 acgataatcc ttgtcgtcat accagttttt gataccacag agttggggtt tggaaatgat
     4441 cagaccagtt tcttctttca cttcacgaat gacagcatcg acaaaggatt cgccacgttc
     4501 aacatgacca ccaggaaaag taatgccagg ccagtcggga ctaactcggt cttggaccag
     4561 gaccttatct ccgtttttaa tcatacacat gttaacaaat tcgactgcct ctcttctgtt
     4621 cattcttcac aacctttaat ctttaatcat aatgcagact tcccgccacc cagccggtac
     4681 agagggcaga agtgatgtta aagccacccg tgtgggcatt gatatccata acttcgcctg
     4741 caaagtggag gccaggtacc agcttacttt caagggtttt aggattgatt tccttgagac
     4801 tgactccacc cttggtaaca aaggactttg caagggacat ttttccagtt acaggaattt
     4861 taagttcttt aatggactga acaagttgtt ctcgttcctt ttcagtcagc tgtttgactt
     4921 tttcaggata tccttgtaca aaaaattcgg ccaagcgttc tggtaacaag gtttttaaag
     4981 cgtttttcaa ggatttttcc cgattttctt ctagaaatgt aaccaagtcc ttctcagaaa
     5041 gttgaggcaa aacatcgagt gagagaacct ccccaccttt gacaaagcta gacatgcgta
     5101 gggcagcagg acctgacaaa ccaaagtggg taaagagtaa atcatgagtg atgacatgct
     5161 taccataact tagggtcaca tcgtccagag aaatcccttg taaggcttta tgtggaaaat
     5221 ctgttaataa aggactttca gcagcctcaa gctcggtgat ggtatgctta aaatggcgag
     5281 caatctcgtg accaaaacca gtcgaaccag tcgaaggata agacttacca cctgttgtga
     5341 caatgagttt ctcacaagtg aaggtttgat ccgctgactt aaggacaaac tggtcatcta
     5401 cttttttaac agaaacgatt tctatttgag tagcaacttg accacctagt tcggtgattt
     5461 tcttttccaa agcttcgata atagtccgag acttgtcact ggctggaaag acgcgtccgt
     5521 ggtcttcgac cttaagttta acaccatttt ctgtaaaaaa gttgatgatg tcatgattat
     5581 cgaactggga gaaaacactg taaagaaagc gtccgtttcc aggaattcca gctagcaggt
     5641 tgtctaagct accattgttg gtcacattgc aacgtccccc accagtccca gctaattttt
     5701 ttccaagttt ccgatttttt tcgatgagga gggttttctg tccataaaag ctactggaaa
     5761 tcgtagccat cataccagca ggtcccccac cgatgacaat agtatcaaaa tgtttcatag
     5821 ctctattgta ccacaaaaaa acaagagatg atggtcacct cttgtcaaga atgcaattaa
     5881 tcaatttcat agcccatcag caaaccgcca tcttctgcat agaaactgca gagaccagag
     5941 gttggtagaa ttttaatatc cgcttgtggg aaggtttcac ggattcgctc tgagagctgt
     6001 tgacaacatt tttcgttatt gcgttgggcc atgacaatac ggccaccagc atatccagct
     6061 tttactaact catcataggc agcttgaact gatttctttg atccccttgc tttttgtagc
     6121 aattcgagag tcccagtttc actagctttt ccgaccatac gaatgttgag aaggccaacg
     6181 accgtaccga taagcttgct caaacggccg ttcttcacca agttatcgac tttggctagg
     6241 acaaagagca acttagtttt ttcttgatag gcggtgatag cttcaaccac ttcttcaaaa
     6301 gacaagccct ggtcaatcaa gtcattcaat ttttctacga gtaggtcaac ttcaccacca
     6361 gcagataaac tatcaatcac atgaatctta gtgtcaggat ggtcttccag ataaatattc
     6421 tttgctagtt gagcactatt gtgactgcca gaaagggtac ctgtgatggt tactaggaaa
     6481 atgtttttgg caccttcaaa tgctcgcaaa tagtcatctg ggcttggaca agccgatttt
     6541 gaagcttctg cagttgcata catggtttcc atcatttggt caatatcgag actggcgtca
     6601 tcaacaaaga cctgatcagc tacttgaatg gttaagggga cacttacaaa ggttgtgtta
     6661 atagctggtg ttggcagttg acgataatca caaccagagt cagcaataat tttccaagtc
     6721 atagaaattc tccatctttg tcagttatac attgacaaag gttctgtctt tttttacaat
     6781 tatatcatga aaacccttga aacaaaagca tcatccgtct gttgtgacaa gtagaaagaa
     6841 aatgttatgt ctgaacgtag aatctctgaa aagtctcttg aaaatctcag aaaatcaaac
     6901 caagaatcca atttattaac cagagaagcc attgaaacag ccctcttgca actcttggaa
     6961 aaaaaggagc tgaccaagat tagtatttct gaattggtca aacgtgcagg tgtttcgcgt
     7021 gcggcctttt atcgcaatta tgactccaaa gaggaaattt tagagagcgt ctttaaacga
     7081 actgtccaca atattatgga acagctgcat cattacgatt taaagacaga cctttatttg
     7141 gtttgggttc accttttccg ggaggccaga aaggaagcta gagtgattca attggccttg
     7201 gattaccatc tggaaaaaat ctttgtccaa gccatgcagg aatttctaga aaaataccat
     7261 gggaaatcaa aaggtgtcag ctcttatctt cattccttct ggagctcagc catcgtctct
     7321 gtccttctaa aatggatcaa ggatggcatg aaggtaccag ctgaaaagat tgcagattta
     7381 ggtttaccat tttttaaaaa atagagaaaa aggagaaaag agatgactga aaaaagactg
     7441 gcctgggatg agtattttgc agcccaagcc ctactaattg cgaatcgttc cacttgtaaa
     7501 cgtgctaaag tgggcgcgat tctggtaaaa gataataagg ttatttccac tggttacaat
     7561 ggttcggtgt cagggactga gcattgtatt gatcacgaat gtttggtcat tgaaggccac
     7621 tgtgttcgca cccttcacgc tgaggtcaat gctatccttc aaggtgctga gcgtggtgtt
     7681 cccaaaggct ttacagccta tgtaacccat tttccttgtc tcaactgtac aaaacaattg
     7741 cttcaggtcg gctgcaagcg cgtggtttat atcaaccagt accgaatgga cgactacgcc
     7801 caataccttt atcaagaaaa agggacagaa ttgacccatt taccacttga gacagtacag
     7861 acagctctta aagaggctga tctaatgtaa aaattatcaa aaataaatgg cttagaaaga
     7921 tttttaaacc gttttttggt ataataagaa gaataaattg aaagaaggaa ttccaaaaat
     7981 gggaaaaatt gaagttatta atcacccact gattcaacac aaattgtcaa tcttgcgtcg
     8041 tacagatact tctacaaaag cttttcgtga gctagtagat gagattgcaa tgttgatggg
     8101 gtatgaagta cttcgtgatc ttccactaga agatgtggaa atcgaaacac caattacaaa
     8161 aacagttcaa aaacaattgg caggtaagaa attggccatc gtcccaatct tgcgtgcagg
     8221 tatcgggatg gttgatggtc tcttgagctt ggttccagct gctaaagttg gccacatcgg
     8281 tatgtaccgt gatgaagaaa cacttcaacc agttgaatac ttggtgaaat tgcctgagga
     8341 cattgaccaa cgtcaaattt ttatagtaga cccaatgttg gcaacaggtg gctcagcaat
     8401 cttggctgtt gattctctta aaaaacgtgg cgcatcaaat atcaaatttg tctgccttgt
     8461 atctgctcca gagggtgtaa aagcccttca agaagctcat ccagatgtag aaatctttac
     8521 agcagccttg gatgaacgtt tgaacgaaca cggttatatc gttccaggtc ttggagatgc
     8581 tggagaccgc ttgttcggta caaaataaga tcgaaaagaa gaatgacttg gaaaagtatt
     8641 tccagtcacg aaaggaggtt gggtttttgt ttctgtctaa tgaaagcaga gcaaaaattt
     8701 gacctttttt gaccaagata ttataatagt cttatcttca gtcagttgac caacaaaatt
     8761 aaaactcaaa aggagaaatg aatgattcct gtagttattg aacaaacaag ccgtggagaa
     8821 cgttcttacg atatttactc acgtcttctc aaagaccgca tcattatgct gacaggtccg
     8881 gttgaagaca atatggctaa ctctgttatt gcccaattgc ttttcttgga tgcccaagat
     8941 agtacaaaag atatttacct ttatgtcaat acaccaggtg gttctgtttc agctggtttg
     9001 gcaatcgtag ataccatgaa ctttatcaag gcagatgtcc aaaccatcgt tatgggaatg
     9061 gctgcatcta tgggaacagt catcgcatca agtggagcaa aaggcaaacg tttcatgctt
     9121 ccaaatgctg aatacatgat tcaccaacca atgggcggta caggtggtgg tacccaacaa
     9181 actgatatgg ctatcgctgc agaacacttg ctcaaaactc gtaatacctt ggaaaaaatc
     9241 ttggctgaaa attcaggtca gtcaatggaa aaagtccatg cagatgcaga acgtgataac
     9301 tggatgagcg cccaggaaac acttgaatat ggctttattg atgaaattat ggccaacaat
     9361 tcattgaact aatgatgata gaaggcaaac tcgactgggt ttgctttttt tggtataata
     9421 gggagagatt tcttagaaag aggatttatc atgtttgaaa aagtcaatcg ctctggcttg
     9481 attatctatc tttactataa tcgtgatgcc aaaaaattgc aggattatgg agatattacc
     9541 tatcattcca agaaacatcg ttacttacaa ctctatgttc caactcaaga agtggagcaa
     9601 ttggtcggac gcttgagcaa ggaaaaattt attaaaaaag ttagggtttg tcatatccaa
     9661 gagttggaaa caccctttgt gggcaatctt tatcgatagg aaaacgttat catagaaaaa
     9721 gttcaaggaa aacattgaca attttctgat aattcggtat attcttaaca gactatttaa
     9781 gaaataagga gacaaaaaga tgaagaaaaa atttgcccta tcgtttgtgg cgcttgcaag
     9841 tgtagcactt cttgcagcct gtggagaagt gaagtctgga gcagtcaaca ctgctggtaa
     9901 ctcagtagag gaaaagacaa ttaaaatcgg gtttaacttt gaagaatcag gttctttagc
     9961 tgcatacgga acagctgaac aaaaaggtgc ccaattggct gttgatgaaa tcaatgccgc
    10021 aggtggtatc gatggaaaac aaatcgaagt aatcgataaa gataataagt ctgaaacagc
    10081 tgaggctgct tcagttacaa ctaaccttgt aacccaatct aaagtatcag cagtcgtagg
    10141 acctgcgaca tctggtgcga ctgcagctgc ggtagcgaac gctacaaaag caggtgttcc
    10201 attgatctca ccaagtgcga ctcaagatgg attgactaaa ggtcaagatt acctctttat
    10261 tggaactttc caagatagct tccaaggaaa aattatctca aactatgttt ctgaaaaatt
    10321 aaatgctaag aaagttgttc tttacactga caatgccagt gactatgcta aagggattgc
    10381 caaatctttc cgcgagtcat acaagggtga aatcgttgca gatgaaactt tcgtagcagg
    10441 tgacacagac ttccaagcag cccttacaaa aatgaaaggg agagactttg atgctatcgt
    10501 tgttcctggt tactataatg aggctggtaa gattgtaaac caagcgcgtg gcatgggaat
    10561 tgacaaacca atcgttggtg gtgatggatt caacggtgag gagtttgtac aacaagcaac
    10621 tgctgaaaaa gcatcaaaca tctactttat ctcaggcttc tcaactactg tagaagtttc
    10681 agctaaagct aaagccttcc ttgacgctta ccgtgctaag tacaatgaag agccttcaac
    10741 atttgcagcc ttggcttatg attcagttca ccttgtagca aacgcagcaa aaggtgctaa
    10801 aaattcaggt gaaatcaaga ataaccttgc taaaacaaaa gattttgaag gtgtaactgg
    10861 tcaaacaagc ttcgatgcag accacaacac agtcaaaact gcttacatga tgaccatgaa
    10921 caatggtaaa gttgaagcag cagaagttgt aaaaccataa tagaaaaatg ttgaaatagg
    10981 gaatgagcct ttgactcact ccctgtttcg atatttaata ctcttcgaaa atctcttcaa
    11041 act
//
LOCUS       DAYYYC010000061        10689 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.061, whole genome shotgun sequence.
ACCESSION   DAYYYC010000061 DAYYYC010000000
VERSION     DAYYYC010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10689
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.061"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(<1..839)
                     /gene="lytB"
                     /locus_tag="ACHBV5_001847"
     CDS             complement(<1..839)
                     /gene="lytB"
                     /locus_tag="ACHBV5_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HFM9967595.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQA"
     gene            complement(881..1867)
                     /locus_tag="ACHBV5_001848"
     CDS             complement(881..1867)
                     /locus_tag="ACHBV5_001848"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFM9967596.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1830..2630)
                     /locus_tag="ACHBV5_001849"
     CDS             complement(1830..2630)
                     /locus_tag="ACHBV5_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFM9967597.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVNQRVCEDGPVFRTGTVVL"
     gene            complement(2880..3260)
                     /locus_tag="ACHBV5_001850"
     CDS             complement(2880..3260)
                     /locus_tag="ACHBV5_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFM9967598.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="ACHBV5_001851"
     CDS             complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="ACHBV5_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFM9967599.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="ACHBV5_001852"
     CDS             complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="ACHBV5_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFM9967600.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3962..4492)
                     /gene="infC"
                     /locus_tag="ACHBV5_001853"
     CDS             complement(3962..4492)
                     /gene="infC"
                     /locus_tag="ACHBV5_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFM9967601.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4508..4639)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4813..5988)
                     /locus_tag="ACHBV5_001854"
     CDS             complement(4813..5988)
                     /locus_tag="ACHBV5_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967602.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWKDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     gene            complement(5992..6579)
                     /locus_tag="ACHBV5_001855"
     CDS             complement(5992..6579)
                     /locus_tag="ACHBV5_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFM9967603.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMTDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            complement(6611..6799)
                     /locus_tag="ACHBV5_001856"
     CDS             complement(6611..6799)
                     /locus_tag="ACHBV5_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967604.1"
                     /translation="MTVTKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGSY"
     gene            complement(6979..9219)
                     /locus_tag="ACHBV5_001857"
     CDS             complement(6979..9219)
                     /locus_tag="ACHBV5_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFM9967605.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            complement(9203..9853)
                     /locus_tag="ACHBV5_001858"
     CDS             complement(9203..9853)
                     /locus_tag="ACHBV5_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFM9967606.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(9921..10490)
                     /locus_tag="ACHBV5_001859"
     CDS             complement(9921..10490)
                     /locus_tag="ACHBV5_001859"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9967607.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
BASE COUNT         3118 a         2395 c         1900 g         3276 t
ORIGIN      
        1 gcttgactat gagaatcgta gacccattct ttttcagcta ttttcccatc aaatttgaga
       61 taaaaccaag attccttatc ccaaatccat tcattggctg ccatgtagcc accagatttt
      121 agataataat agtgaccatt ctcgaaaatc cattctttat cagcatagtt tccattttct
      181 tttatgtaaa accaagattg gtattgtttg tcaaaaagcc aaccttgctg tactttggca
      241 ccactagcat tcacataagc ttgattaatc cactgacttg ttagtagata accaccggat
      301 ttgaaataat agtccttccc tttaatttgg agccattctt tctctgcgtg ctgtccatct
      361 gctttgatat aaaaccaagc atcgtattga gaatcataga cccagtcttc tattactttg
      421 gcacctgttg caccaacata ggaagttcct acccaagcat ttcttttcat ctttccatct
      481 tggtcaagat aataaaaggc tcccttgtct tctacccatt ctgatttggc catatagcca
      541 ccagatttga ggtaaaaata gtcgtcacct tgctttagcc attcattttc agcatagtta
      601 gcatctgctt ttatatagaa ccaagattga taatgagtat caaaaaccca ctcattcgct
      661 gcttgactgc catcttcttt cagatactgt tttccttgcc aagtaccatc actagccatt
      721 gcaccctctg gactagctaa gaaaaatagc agagctaaaa aaataaatct tactttcttc
      781 attaaccttc ttcctctgtt cttatttatt ttattgtacc aaaattctcc taaattcata
      841 ttacaaacta ataaaaaatc aagaacagat tgattgcagt ttacctcaga gactctttta
      901 cttcctgacg gagttcttcc agactgctaa taccgtattt atccatgact tttggtaaat
      961 tttcgatgat gtcagggcag gcataaggat tggtaaagtt agctgttcca actccgatag
     1021 cagatgcccc agccagatac atttctaggg cagcttcagc cgaatccact ccccccattc
     1081 caatgatagg caggtctgtt gtttgggcta cttggcggat gagtttgagg gctactggaa
     1141 agactgctgg acctgacatt ccacctgttc cattggccaa gattggtttt ctggttttga
     1201 ggtcaaagcg cattccaacc agagtattga tcatggtcaa gccacttgct cccgcatctt
     1261 ctgcagcttt tgcgacagta acgatatcgg tcacactcgg ggttaatttg acataaactg
     1321 gcacttctga ggcttccaca gctgctttca ccacatcata agccaaatct ggatcttgac
     1381 caatcaaaag tccatgatta cagtggtcaa cattgggaca agaaatattg agctcgatag
     1441 cttttacatt agttgccttg gaaatcccat gagaaacagc tgcatactct tgttttgaaa
     1501 aaccagctac attggcaata ataggaagat ttggatattc tctttccagc caaggtagct
     1561 tttcagccaa aacaacctct aaaccaggat tttgcaagcc aattgcattg agcataccag
     1621 caggcgtctc tgctactctt ggagttgggt tcccaaaacg tggttcaagg gttgtcgcct
     1681 tgatcataat agaacctaaa aggtttaaat catagtactt ggcatactct tgtccaaagc
     1741 caaaacaacc tgatgctgga ataatcggat ttttcaaatc caaaccaggt agagacactt
     1801 gtaatcgatt tgtagtcata attttctcct tataatacaa ctgttcctgt gcggaaaaca
     1861 ggaccatctt cacagacgcg ttggttgacc gtctcgcttt ctggtacttt tagaacacag
     1921 gcatagcaag ctcccatccc acaagccata cgagattcca gagataaata ggctcttggg
     1981 tgatcatcaa aggtttgatt gatatacttc atcattcctg gagccccaca cgagtaaaca
     2041 gcatcaaact gactatctaa atcattgata acaacggaaa catttccctt gatgccataa
     2101 gaaccatcat ctgtcgttac aaagacctga ccatactgag ccaattccgt tttcaaaata
     2161 acagcatcct tattagcaaa accgaggact gtcactactt tcactccacg ttcatgcaat
     2221 tccttggcca cctcaagcaa gggtggaaca ccaatcccac caccaacaag gagaacctga
     2281 ttctgctcat caaggtcaga caagtcaaaa ccatttccct gaggccccat cacatcaaga
     2341 gtgtctccct gacttaaggt tgaaaaaatt gcagtcccag ctccctcaat ccgataaatg
     2401 aggtgacact gcttgtttgc cttgtcaata gacgaaattg aaataggacg acgtaaaaga
     2461 tgggcatcgt ctggtacacg cagatgaaga aattggcctg ctcgcatggc ttcaaccatt
     2521 tctccttcta ggactaattc aaagattgct ggcgcgattt cctcttgtgc aaccaccttc
     2581 atggtttcca accgaatgac acccaaacgc ttcttacatg tgggattcat aacttttcct
     2641 ccttaaattt taaggggacc agataaagaa aagaccttgc tagtgcaagg cctcagttaa
     2701 aatcgtacaa cacaagagag cacactcaaa aagtctcctc tagaaaattg cactattctt
     2761 ttatctgaca ccttgtgagt ctctctggac tccccttaaa ggttgaattt ttattagtat
     2821 actctttcag ctaaaaaaag tcaagtaaaa aacgaatatt ctacttaact tgcacgaaat
     2881 tatttttcac gaatgacttc gaccttatat ccatcagggt ctttgacaaa gtaatagttt
     2941 ggtgtagttc ctggtagacc atttggctca gtcacttcat agccttttgc actgtgttct
     3001 tgatgaagtg cctcaagatc aggtgtactg agggcgatat gggcaaaccc atcaccaacc
     3061 acatacggac cgtgatcgta gttataagtc aactccaact catagtcatc accctcaaga
     3121 cctagataga caatcgtgaa ggcatggtct ggaaaatctc tgcgacgcaa ttctttaaaa
     3181 ccaaaagcat cttgataaaa tgcgattgat ttttcaagat tttctactcg taagcaagtg
     3241 tgtagcattt ttgaagccat atttttctcc tttattttta aaaagactgg acaatcctgt
     3301 tccagtctca tcagttgtta tttaccaagt tttgctttag ctgcatctgc aagagctgtg
     3361 aaagctactg catcgttaac agccaagtca gcaagcattt tacggttaac ttcgatctca
     3421 gccaatttca aaccatgcat caattgtgag tatgaaagtc cgttcatacg agctgccgca
     3481 ttgatacgag tgatccacaa tttgcggaag tcacgttttt tctgacgacg gtcacggtat
     3541 gcatagtagt aagagttcat tacttgttct tttgcagtac ggaacaagat gtgtttagct
     3601 ccatagtaac cttttgctaa tttaagaata cgtttacgac gtttgcgtga tacaacgcca
     3661 cctttaacac gtgccatgtt ttatttcctc caaatatttc ctagaattgt ttacttacag
     3721 tcaagctatt atttcaagcg agtaagcatt gctttgatac gtttgtaatc tcctgaatgc
     3781 accatagatg ctttacgaag atgacgacgt tgtttcttag tttttccgtg gaaacggtga
     3841 gaagtgtaag cacggaaacg tttaagtcca ccagaacctg tacgtttgaa acgtttagct
     3901 gatgcgcggt gtgttttttg ttttggcata attttttctc ctttatttaa ctttctgaca
     3961 attatttttt gtcagtcgct ggcgccaatt gcatgaacat ttgacgtcca tccattttag
     4021 cacgttgttc gatgatggca atatcttgag ttgcttcagc aaactcggct aaaacttttg
     4081 caccaatctc tttatgggta atcatacgac ccttaaagcg aatagatacc ttaactttat
     4141 ttcctttttc aaggaactta cgtgcattac gaagttttgt atcaaagtca cccttgtcaa
     4201 tagttggact tagacgaact tctttcacag taacaacgct ttgtttttta cgttgttctt
     4261 tttgcttctt ctggtactca aatttgaact taccgtagtc cataattttt gcaacaggcg
     4321 gtttggcttg gggttgaatc aatactaggt caacattagc gttatcagcc aaagcttgcg
     4381 cttcactgag tggcttgatg cctagctgtt ctccttcaag accaatcaag cgaacttcac
     4441 gtacacgaat ctcatcattg atgaataagt cttgctttgc tatggttttc acctcttttg
     4501 ttttattaga gaaaaacaat agcggactcg taaatataca agcccgcacg ttatgatagc
     4561 gtttcttcga aacttttcat ccgtagggcc aggcaactta atgtcacaag gcgagaagct
     4621 ctcacttctg cttttctcaa cttttatatg ataccaagtt ttctagctct tgtcaagata
     4681 aaaagttatt ttttgaaaag tttgtgtttg tattttggtt tggttttcga atcaaaaaga
     4741 gagaatcaag ttgattccct ctctatgtta gtttttactt attttcccta cctataggaa
     4801 agctagaatc tattaaaaaa ttcttttttt ctgtgaactt ccccatcttt caataaatag
     4861 aattcccaat agcaaaaaga taatcaggca aggaagtaag accattccca tgctccaatt
     4921 tagatcgaca ttatcaatct gcttaggtaa tcttccagat aaaatctcca ctgaacgcaa
     4981 gtaagtaaag ggaatcagat gtgcaatcct ttgaagaggc tgaattgttt ggatgccaaa
     5041 caataagcca acaatcccaa tgagtgaaag aaagaggaca ggcatttttt gcttgaaaaa
     5101 gtaagcaatc aagtacacaa cttccacaat gacgataaag gctaagaaag ctaagagcaa
     5161 gccaggaaat aatacatctt gtattttccc aatagttact tcttgattca ctaagctata
     5221 aattgggtag ggataatcta actgtccaaa accacttatc agacttccca ctagaaaaga
     5281 aaagccacag attccgataa acagcacagt tacatatccc actccaactc caagagagga
     5341 tattgcaaat gtcacttttg aaacaggata taagtgagct gtgtccagat gattttgata
     5401 tctttctgca aatagttgtg ttagcataaa aataatcgca accacaaaca agcttgggat
     5461 gataacctct aaaatccaga caatctgatc aatcccgtgg gtcggaaact ccaaagtatg
     5521 tgcttttatg ttcaagggat acagggcttg gtaaatcttc cgttcgcggt caacccccat
     5581 ttttaagcca gagctagcag tcgggtcatt tgatacaaat tcataattct tctcttcatc
     5641 tttccactgc agatagtagg cttctttcca gcgcccttct tttagtaaag ttagaatttc
     5701 tgtctttcgc gtcaaaagat ttttttgcac gtctaaatta tttttagcaa actggtattc
     5761 ctccgagctg gtatcagaca tttgggagag tttctcttca ttttcattga tagccctctc
     5821 gttggctgca atgcgacttt ccaacctgct ctccaagctg tgtgagtttg cagtctgact
     5881 atttaaataa aaggtaacac cgagtacaga tacaaataaa gctaagataa tccagtttaa
     5941 acgacttttg aaaacttttt tcaataaaaa tagactaaca tctttcataa actaaacctc
     6001 ttctatctgc ccctgatgaa tggttactac tctatcgcag atatcaacca actcttcctt
     6061 atagtgggaa cttaaaagaa ccagctgttc ttgtctatcg atttgtgcta gcctatcaaa
     6121 aaacttctgt cgataatact cgtctaagcc atttgtaatc tcatccatga gccagcattt
     6181 ggcctgactg agaaaataca tagcaatcac caagcgttgc ttcatcccta aggaatactt
     6241 gcggatggga agactgatat agtcagtcat ttcccagtag gcgatttcat ctctcaagtt
     6301 taggtctgac ttccagatgt tttttatgag acgaaggtag tccatcccac ttaagtttcc
     6361 atccagccat tcaacgctct cataataaaa caaagaagga ggaactgcga tgtgtccact
     6421 actaagggga agcaacttgc tcatagctcg gaatagtgtc gtctttcccg agccattgat
     6481 agcaagaagg ccataaatcc tacccttttt aaaggtaaaa tccgcatctt gcaagatgac
     6541 ttgtcgcgtt tttaaggtaa catgagtaag atttaacata tccagccctc cttttctcac
     6601 tctttaagga ttaataactt ccagtatagt agtttatgac ctcataacga gcgtagttcc
     6661 agcctccgcc aactttatac tcagaatagc tgtaataacg agaccattcc ggaatccaag
     6721 catactgatg gtcgtgatag ttggtactat attccaaaac cgtattccaa tcatacttgt
     6781 aacttttagt gactgtcaca gcagatacac tggactgaag aagaccaata gattataaac
     6841 taactaacta aaacaacttt tgctgatttt taatgatttt atatcctcaa tattgaatac
     6901 gttttcatta tgccgttttt atcattatta tgcaacaaat ttttagttta tttcactaat
     6961 ctacaacatt tatccttcct atcgaacact ttcgattttc caactatcca accccttaaa
     7021 acgtatagct ccttgctggt cagttcgata aactttgcta ttgatacctt ccagtcgtgt
     7081 caatgtttcc tgatggggga gtttcattcg attgctcttt ccaactgaga taagagtaag
     7141 ctctggtttg agtttttcta gaaaggctgg acttgatgat tttttattgc catgttggct
     7201 agctttcaaa acatttactt tcaagtctgg atagtgcttc agcaagtcct tctctccttt
     7261 ctcctccaaa tttcccgtga agagaaattg cttatccaag aatttcccat acagaactag
     7321 ggtatcatcg tgtcctccat ctcccatttt ccttggagat agaacttcta actgacttcc
     7381 aaaaatgggc aagttctccc ctactatcat actacgcacc tttgtttgag tcgcctgtag
     7441 ttctgccaca aattccttct gtttcagact gtcttttgat actagaatct cccctacatg
     7501 gaaagccttg gtcatctctg acaaatctcc aacatgctcc ttgtccgtgt tagtcaaaat
     7561 tagctggtca atcttagcta ctcctcgact tttgagatag ggtatcaagc ttcgctgggc
     7621 attgctggtc gtcatctttt cttgccattt tttgattttc ttataagatt ctgccttacc
     7681 acctacatct atgagaatgg ttttcccagt tacatcccgt aggaaaatac tttctccttg
     7741 ccccacatcc agcatggtga tttcattttc cagtggatgc ttggtcagga gaaagagccc
     7801 tgtaatcaat aagcacaata ccgttagctt tttaatgttt ttcctcaaat catagaccaa
     7861 agccaaagaa attaacaata ggattaaaag ccattcattg ggttgtccaa agacaagcgg
     7921 tctacttgcc acctgcgaga ccaagcgaat aatgccctct aaccattcaa agataaagtt
     7981 cagctgaatg actggataga gaaaggaaag gacaaataag atagacaaga gcggtaagaa
     8041 gaccaagtca aaaagaaagg aaaagacaaa ggtcaaaagg atagaccaag gttgaaattc
     8101 cgcaaaatag aaggatagaa tgggcaatat gcccaaggag atgactagac tttcactagt
     8161 aacagccttg agcccctccc cttctttgct ggtcatggtc aggataaaag cataagcaca
     8221 ggacaagact cctcctgctg tcaagaaaaa gtttggcatg acaataaaga ggacaagcac
     8281 cgtcaaggca aaattatcca agcccttaac cccatgttga gccagtagct tttgcaagag
     8341 actgcgaata accgatgctg aaaatccagt tagtcccgca tagataaggg aaaagggata
     8401 agtcagccac ttcaactttt cttgtgtcaa gcccaatcgt aaaagtagtt tcttaaatcc
     8461 gtccatgaaa aaccctacct gcatacctga caaggcaaaa aggtgaataa ttcctaaact
     8521 ggaataaagc tcattcatct cctcaaaatc ggtgtccaga tgtcctagca agagtcctgt
     8581 catgtaattg cgcatagggt ctgggaagtg catcttaatc caaaccacag cctttcgacg
     8641 taaactggac aggttttcac ctatatccca actgccaacc ttttggagtg actggattct
     8701 tttaatattg agtgtctggt aaattccctg agtcttcaga tagccttggt agtcaaagcc
     8761 accaaaattt ctctgccctt ctggctccga aagcttccct tctagtccta tctcatgaag
     8821 gtcagttaaa gcttgaaagg cttctttctc ctcctcggac tggagtttat aatagacttg
     8881 gaaagcacga ccatcagact taccacgaaa ggacagactg tcaccgttaa ccttaatagt
     8941 gtctggtaaa atccgtaccc tttcaacaga atccaccaaa ttttgactca cttgactctg
     9001 ttgccaagtt tgaaacagaa accagaagcc aaagactcca caaatcacta gaactttacc
     9061 tgctgatttc caaggaaatt ggataaagag gcagactagc agaaaaacaa aacccaacaa
     9121 agcaaaatag gatactgaga aaatggcgta gtaaagccat agtaacagaa aactcaggta
     9181 aattagggga atagagaaat tcttaatcca ctgtaacata gtctttaagt ttttctatgg
     9241 tcttggcacc aatgccagag accttcttga gctcgtctac tgacttgaac ttgccatttg
     9301 cctcacgatg gtcaataatg tcctgagctc gttttcctcc cagtcccttg acctgcttga
     9361 gttcttccag actggccttg ttgagattga ccttcttttc cttgcttgtt gaagaagctg
     9421 tccccgaacc agtctgttga ctaactgctt cttctccctt agtaggaacg taaaccagag
     9481 cctcatcact aactttctga gctagattga gcgacttgct gtctgcttgc tctgtcaagc
     9541 caccagcctt ctgaacagca tcattgactc gactacctac aggcaagtca taaatccctg
     9601 gcgatttgac agcacctttg acatctactg tgattagatc ttgttcaact ggttcttcct
     9661 tctcttcctt gttcacttcc tttccggtcg atgagtcctt ggaaacagct gcaacttcag
     9721 cctgcaaatt cgtctctttg acagatgttt gtggagctgg ctttagcagg aaaaatcctc
     9781 ctacaagcaa gcccagacca gtacagatga cgatgatttt atactctttg attttctcga
     9841 taattgcttc catattttct cctctcttag attattcgta agaggaagaa aaaacagtcg
     9901 aaaaatttct tttcaactgc ttatttattt gcaaaatagt cttccttggt caagacataa
     9961 tgaactcttg tcacgattcg gcctttttca tgctggtcca tacaagcata tggttctgca
    10021 tgggaaaaac gcatgcctga tttctccatg acctttcctg acgcgggatt agccttatcg
    10081 tgaagggcag tcaacttatt catccctatc ttctcaaaag ctagctcaat cacagcacga
    10141 ttggcttctg tcgttaatcc ttgattccaa tactttttat tgataatgta gccaatagct
    10201 gccttcttaa gaacaggatc aatcttgtgt aagtcaatag ttccgataaa cttgccgtta
    10261 tcttttaatt caatccccca acgtcccaag ggattagcca agtagaactg agcaatgtta
    10321 ttcttggttt cttccaagct ttgattggtt ggaaaagtgt aacgtgtatt acccttgtcc
    10381 gaggcatagt caaacattgc ttccgcatca tccaaagtta caggtctaag caataaacgc
    10441 tccgtttcta tagacggata ctgggcaaat ttcacaaata ttgattccat acttttccct
    10501 ccattagagc ttgattttca ctagtctagc ataaaaaaat ttggatgaca agtttttctt
    10561 gatttttgaa gcggtttcat atacaatgaa accgtcacat ttttgattta tgaactggaa
    10621 tgtgacaacc aaaacaagac cgtcaattga aaggtaggtt atctcaatgt taatcggaat
    10681 cccaaaaga
//
LOCUS       DAYYYC010000062        10031 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.062, whole genome shotgun sequence.
ACCESSION   DAYYYC010000062 DAYYYC010000000
VERSION     DAYYYC010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10031
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.062"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(71..307)
                     /gene="rpsT"
                     /locus_tag="ACHBV5_001860"
     CDS             complement(71..307)
                     /gene="rpsT"
                     /locus_tag="ACHBV5_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFM9967608.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(375..1295)
                     /gene="coaA"
                     /locus_tag="ACHBV5_001861"
     CDS             complement(375..1295)
                     /gene="coaA"
                     /locus_tag="ACHBV5_001861"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFM9967609.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            1493..1897
                     /locus_tag="ACHBV5_001862"
     CDS             1493..1897
                     /locus_tag="ACHBV5_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967610.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGRCFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            2104..2694
                     /locus_tag="ACHBV5_001863"
     CDS             2104..2694
                     /locus_tag="ACHBV5_001863"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM9967611.1"
                     /translation="MSKMYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDF
                     GSQLLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEK
                     NNAKATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETSGDLTIVIQ
                     KKQGAPSAKSKMEGVFGNCEILKKDKGYYILRSVKE"
     gene            2691..3968
                     /locus_tag="ACHBV5_001864"
     CDS             2691..3968
                     /locus_tag="ACHBV5_001864"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFM9967612.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILVPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            3986..4648
                     /gene="deoC"
                     /locus_tag="ACHBV5_001865"
     CDS             3986..4648
                     /gene="deoC"
                     /locus_tag="ACHBV5_001865"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFM9967613.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            4635..5024
                     /locus_tag="ACHBV5_001866"
     CDS             4635..5024
                     /locus_tag="ACHBV5_001866"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFM9967614.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            5114..6166
                     /locus_tag="ACHBV5_001867"
     CDS             5114..6166
                     /locus_tag="ACHBV5_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HFM9967615.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            6310..7845
                     /locus_tag="ACHBV5_001868"
     CDS             6310..7845
                     /locus_tag="ACHBV5_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9967616.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            7838..8896
                     /locus_tag="ACHBV5_001869"
     CDS             7838..8896
                     /locus_tag="ACHBV5_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9967617.1"
                     /translation="MFKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            8899..9855
                     /locus_tag="ACHBV5_001870"
     CDS             8899..9855
                     /locus_tag="ACHBV5_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9967618.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            9940..>10031
                     /locus_tag="ACHBV5_001871"
     CDS             9940..>10031
                     /locus_tag="ACHBV5_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM9967619.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGI"
BASE COUNT         2863 a         1766 c         2310 g         3092 t
ORIGIN      
        1 gataattgcg attttcattt tctacctttt cctatttgga gacaaaaaaa cagcctctat
       61 ggactgtttc ttatttagca agtttagctg aaagacgagc tttatcgcgg cttgctttgt
      121 ttttgtgaat caaaccttta gtttctgctt tatcgatagc tgagctagca gcacggaaaa
      181 gttcttcaga tgggtttgct tcgaaagctt ttatagcagt acgcatagct gatttttgag
      241 ctgagttctt ttcgttttgt ttaacgttca attcagcgcg tttgatagct gatttaatgt
      301 ttgccaatgt tcttacctcc atatttacta actataccat tatatatgaa aacttacgtt
      361 ttgacaaggg aaaattattt ttttaagtaa atttcatcga tttcatggtt cttgctttta
      421 tgaagaatca cttctgcacg atttctggtt ggttcaatat aattttgtag atttgtgaga
      481 ttgatactgg tccagacctg atgggcaaag gcttccactt ccccaatcgg catctgagta
      541 aaacgataat agtagctatc agggtcgttt tgggctagac tcagcatttt caagaaacgg
      601 tccagatacc aactttcaat atcatccact ccagcatcta catagatgga aaagtcaaag
      661 aagtcagtga tatagagacg atcgttttgt ggattttgaa agacattgat tccctcaaca
      721 attacaaaat cagcagcttt gacactttgt ttctcttcgg gtacgatgtc gtaaacttca
      781 tgagaataga caggaatatc tacatcttgt ccatttttga tgcggtccaa gaagttgaga
      841 agagcttcca tatcatagct ttcaggaaat cctttacgat ttaaaatccc ctgctcaatc
      901 aaggtttgat tgggatagag aaaaccatca gttgtaacca actcaaccgt agcatctgta
      961 aacgtacggg acagtaggat ttgaagtagg cgactggttg tggattttcc aacggcaaca
     1021 ctcccagaaa ccccaataat aaaaggttga gatttacttt cacgttggag gaaaattcct
     1081 tttgaaaagg ctaaatcttc cttagttcgc ttgtaaatct gaatcagatg agccaagggg
     1141 agatagatat ctgtaacgtc ttggagactg atttggtcat taaaactctt gatagattcc
     1201 aattcttctt ctgtcaaagg aggtgttgtc tttcgatgta aagattgcca agtctggcgg
     1261 ctgatttttt caaaatgtaa aaattcgttg gtcatttgtt ttcccctaga tattttgtct
     1321 atcataccat aaaaatctaa aaaaataaag cggtttcttg aatgtggtaa gtcaatggta
     1381 tatagtataa gtgatcaatt tattgatgaa ataggagata gattctactg atttataagt
     1441 ttataagctt ataaaggggg ctttttagtt cacaacttat aggaggtgta ctatgaaaat
     1501 cttaaaacgt tacatattgg aactctgttt tattttaagt tttgctttac cttttataaa
     1561 aggagccaat gcagataatg gtagatgctt tgtggaaacc tattacggtt ttactttttt
     1621 gatggaacat gctattgtaa cagctgtctt tatctattcg tttttaattg ctttcttact
     1681 aaaaaaacga tgggcgaaat ggattgctgc tggtagttat tgctttttag tcctatggat
     1741 tgcgacagag ggttatttct tccgcatgtc actagaagat ttgatacgac tttggacaag
     1801 tttggaaatc ctgacacaaa cgtatcagtt gggcttttat ctaaacattt tgttgggaat
     1861 tttgttgata ataaagtatt ttaaggttaa gcaatagaaa taataatctg cctgattata
     1921 gatgataaac tttttgtttt tatctggact gtgatattta tagttctaaa tggtttatta
     1981 tttataagtg ttgaaagaga ttgaagaaaa tggcttcgtg actcgctttc ttcggtcttt
     2041 ttcgttttat tatcaatttg taaacgattt acaatttgag tcaaattatg gtaaaatagt
     2101 gtcatgagta aaatgtatta tgcagaaaat cctgacgctg ctcacgacat tcatgagttg
     2161 agagtagagt tgttgggaca aaaaatgacc tttttaacgg atgcgggtgt ttttagcaag
     2221 aaaatagttg actttggaag tcaactattg ctcaagtgtc ttgaggtcaa ccaaggagaa
     2281 actgtccttg atgtaggctg tggttacgga cctttgggtt tgtccttagc taaggcttat
     2341 ggagttcagg ctactatggt tgatatcaac actcgtgcct tagatttagc tcggagaaat
     2401 gctgaaaaaa ataatgcaaa agcgacgatt ttccagtcca acatctatga acaagttgaa
     2461 ggacattttg atcatgtcat ttccaatcct cctatccgtg cgggcaagca agtcgttcat
     2521 gaaatcattg agaaaagtaa agatttcttg gaaactagtg gggatttgac aatcgtcatc
     2581 cagaaaaaac aaggggctcc aagtgctaag tccaagatgg agggtgtgtt tggtaattgt
     2641 gaaatcctta aaaaagacaa gggatactat atccttagaa gtgtgaaaga atgagagcag
     2701 ttgatttaat acaaaaaaaa cgagacggtc aagaactgac ttcaagtgaa attgaatggc
     2761 tggtagaagg ctatgtgtca ggaactgttc ctgattatca gatgtctgcc tttgctatgg
     2821 ctgtttattt taaaggaatg acgactcgag aaatctctga tttaacgatg aatatggtta
     2881 agactgggca agagtttgac ctgtcagcca ttgatggtgt gaaagttgac aagcattcta
     2941 ctggtggtgt cggcgataag gtaaccttga ttttagttcc tcttgttgct agcttcggtg
     3001 tgcctgtagc aaaaatgagt ggtcgtggtc ttggccatac aggcggaaca attgataaat
     3061 tggagtccat taagggctat caagtagaac gtagtcaaga ggattttatt cgtcaggttc
     3121 aggatattgg agtatctgtc attgggcaat cagaccagct ggtcaaagca gataagcttc
     3181 tctatgccct tcgtgatgtg accgcaactg tcgacacgat tcctttgatt gcgagttcgg
     3241 tgatgagcaa gaaaattgcg gcaggggcgg atgctatttt gctagacgtg actgtcggtg
     3301 agggtgcctt catgaagacg gttgatgagg cgcgtgagtt ggctcaaact atggtagatc
     3361 ttggtaaggt tgttggacgg aagacagtag cagtgattac ggatatgagc cagcctttgg
     3421 gacgagcgat tggaaatcgt ctggaaatcc ttgaagcatt ggagattttg caaggtcaag
     3481 gacgtcagga tattacccac tttatttgtg aattggctca aattatgctt ggtttggcaa
     3541 atgttaacaa aactgttgaa gaagttcgcc aacatcttga gaatggtcaa gcactggcta
     3601 agtttgagga aatggtgcaa gcccaaggtg gagacttgga agacctctat cgtcctgtaa
     3661 atgtagctca tgtggtggaa atccctgctc aggaaacggg tgtcatttca gctcttccag
     3721 ctatggactt tggtctttat gccatgaggc tgggtgctgg tcgtgcagtt aagtctgatg
     3781 ccttggacta tgaaacagga attgtttttg aaaagaagat tggagactcc gttcaaaagg
     3841 gtgaaattgt tgcaaaagta tacacaaatg aaaaaattcc acctcaacta gttacagatt
     3901 tccaaaaatg tgttaaaata agtgatgaag tgaaaaaaat ccgtgaaatt gtagaaatca
     3961 tctcctaaat ggagggaaaa ccgaaatgaa attaaataaa tatatagatc atacgctttt
     4021 aaaacaagat gcaaagaaaa aacaaattga tagtttgttg tctgaggcta gagagtatga
     4081 ctttgccagt gtttgcgtta atccgacctg ggttgaacat gctaaaaaag gacttgaagg
     4141 cacagatgtt aaggtttgca cagtagtagg tttccctttg ggagcaacaa cttcagccgt
     4201 gaaagcattt gagacaaaag aagctatcca aaatggtgca gatgagattg atatggtgat
     4261 caatgttgga gctctcaaat caggtaattt agccttggtt gagtcagata ttcgcgcagt
     4321 agtggaagca agtggtgata agttagtgaa agtcattatt gaagcttgcc ttctgacaga
     4381 ccaagaaaaa attgttgttt gccaattggc ccaaaaagct ggggctgact ttgttaaaac
     4441 atctactggt ttttcaactg gtggtgctac gatagcagat gttacattaa tgcgtgaaac
     4501 agttggatct gatatgggag tcaaggctgc tggtggagct cgttcttatg cagatgctct
     4561 tgcctttgtc gaagcaggtg cgacccgtat cggaacgtca gctggggtag ctattttaaa
     4621 aggagaattg gcagatggcg actactgagt tgattgaact ggcaattgaa accagcaaac
     4681 atgcatatgt cccctattct cactttccta tcggagcagt tttagtagcc aaagacggaa
     4741 gtgtttacac gggagtgaat atcgaaaatg ctagctatcc tttgaccaat tgcggtgaga
     4801 gaacagctat ttttaaggct atatctgaag gccaaagaga attttcagaa ttgattgtct
     4861 atggtcaaac tgaaaaaccg atctcgccat gtggtgcttg tcgccaagtg atggctgaat
     4921 tttttgaaca agatctaaaa gtgaccttag tcgcaaaaga taaatcgacg gtcgagatga
     4981 cggtcgggga attacttcca tactctttta cagacttaaa ctagtctgag tcgctctctg
     5041 agtggcacgg tccttgtggc caaccaatcc atacttgcaa catcgttgca catcttattt
     5101 aggaggttca gtaatgaaca agaaacaatg gctaggtctt ggcctagttg cagtggcagc
     5161 agttggactt gctgcatgtg gtaaccgctc ttctcgtaac gcagcttcat cttctgatgt
     5221 gaagacaaaa gcagcaatcg tcactgatac tggtggtgtt gatgacaaat cattcaacca
     5281 atcagcttgg gaaggtttgc aggcttgggg taaagaacac aatctttcaa aagataacgg
     5341 tttcacttac ttccaatcaa caagtgaagc tgactacgct aacaacttgc aacaagcggc
     5401 tggaagttac aacctaatct tcggtgttgg ttttgccctt cataatgcag ttaaagatgc
     5461 agcaaaagaa cacactgact tgaactatgt cttgattgat gatgtgatta aagaccaaaa
     5521 gaatgttgcg agcgtaactt tcgctgataa tgagtcaggt taccttgcag gtgtggctgc
     5581 agcaaaaaca actaagacaa aacaagttgg ttttgtaggt ggtatcgaat ctgaagttat
     5641 ctctcgtttt gaagcaggat tcaaggctgg tgttgcgtca gtagacccat ctatcaaagt
     5701 ccaagttgac tacgctggtt catttggtga tgcggctaaa ggtaaaacaa ttgcagccgc
     5761 acaatacgca gccggtgcag atattgttta ccaagtagct ggtggtacag gtgcaggtgt
     5821 ctttgcagag gcaaaatctc tcaacgaaag ccgtcctgaa aatgaaaaag tttgggttat
     5881 cggtgttgat cgtgaccaag aagcagaagg taaatacact tctaaagatg gcaaagaatc
     5941 aaactttgtt cttgtatcta ctttgaaaca agttggtaca actgtaaaag atatttctaa
     6001 caaggcagaa aaaggagaat tccctggcgg tcaagtgatc gtttactcat tgaaggataa
     6061 aggggttgac ttggcagtaa caaacctttc agaagaaggt aaaaaagctg tcgaagatgc
     6121 aaaagctaaa atccttgatg gaagcgtaaa agttcctgaa aaataatgga tggaagtcat
     6181 ttcttaggaa gcggccaagg gccgcttttt taagagttga gacaaagtca ttttgtctca
     6241 gtaaagcttg ctactagaca aactagcaag ttttattgaa ataaaataag actctgaaag
     6301 gaagagcaca tggcacacga aaatgtcatt gagatgcgtg atattaccaa ggtgtttggt
     6361 ggatttgttg ccaacgacaa aatcaacttg cacctacgaa aaggtgaaat tcatgcactt
     6421 ttaggagaaa atggggctgg taagtccacg ctaatgaaca tgttagcagg ccttcttgaa
     6481 ccaactagtg gtgaaatcgc ggtcaacggt caagttgtca atctcgactc cccatctaaa
     6541 gcagctagct tgggaatcgg gatggttcac cagcacttta tgttggttga agccttcaca
     6601 gtggctgaaa acatcatttt aggtagtgaa ttgactaaaa atggtgtgct agatatcgct
     6661 ggagctagca aagaaatcaa ggctctttct gaacgttatg gcttagctgt tgacccttct
     6721 gccaaggtag cagatatctc agttggagcc caacaacgtg tagaaatttt aaaaacactt
     6781 tatcgggggg ctgatatcct tatctttgac gaaccaacgg ctgttttgac tccatcagaa
     6841 attgatgagt tgatggctat tatgaaaaat cttgtcaaag aaggaaaatc aattatcttg
     6901 attacccaca aattggatga aattcgcgca gtttctgacc gtgttacagt tatccgtcgt
     6961 gggaaatcaa ttgaaaccgt tgaaattgca ggggctacca atgctgattt ggcggaaatg
     7021 atggtaggac gttctgtttc ctttaaaaca gagaagcaag cctctaaacc aaaagaagtg
     7081 gttttgtcta tcaaagattt ggtggtcaat gaaaaccgtg gtgttccagc tgttaaaaat
     7141 ctgtccttgg atgttcgtgc tggagagatt gttggtattg cggggattga tggaaatggt
     7201 cagtctgaac tgattcaagc cattacaggt cttcgtaagg ttgaatctgg tagcattgag
     7261 ctaaaagggg attcaattgt aggcttgcac ccacgtcaga ttacagaact aagtgttggg
     7321 cacgttccag aagaccgtca ccgtgatggc ttgattttgg aaatgatgat atctgaaaat
     7381 attgcccttc aaacctacta taaagaacca catagtaaaa atggaatttt gaattattca
     7441 aatattactt cttatgctaa aaagctgatg gaagagtttg atgttcgcgc tgccagtgaa
     7501 ttagttcctg cagctgcact ctcaggagga aatcaacaaa aagcaattat tgctcgtgaa
     7561 attgatcgag atcctgatct ccttatcgtt agccagccaa ctcgtgggtt ggatgtcggt
     7621 gccattgagt atatccacaa acgcttgatt gaagagcgtg ataatggcaa ggctgtcctt
     7681 gttgtcagct ttgaattgga tgagatttta aacgtctcag accgtattgc cgttatccac
     7741 gatggtaaga ttcaaggtat tgtatcacca gaaacaacca ataaacaaga acttggtgtc
     7801 ttgatggctg gtggaaactt gggaaaggag aagagtgatg tttaaaaaat tacaacaaat
     7861 ttcggttccc ttgatttctg tatttctagg aattttactc ggagccattg tcatgtggat
     7921 cttcggttat gatgctattt ggggctacga agaattgttc tatacagcct ttggcagtct
     7981 gcgtgggatt ggagaaatct tccgtgctat gggtcctctg gtcttgattg gtcttggttt
     8041 tgcggttgcc agtcgagctg gtttctttaa cgtcggactt cctggtcagg ctttggcagg
     8101 ttggattctc agtggttggt ttgccctgtc gcatccagat atgccccgtc ccttgatgat
     8161 tctagcaacc atcgtgattg ccttgattgc tggtgggatt gtcggagcga ttccaggtat
     8221 tcttagggcc tatctaggga cgtcagaggt tattgtaacc atcatgatga actacattgt
     8281 cttgtatgta gggaatgcct ttatccatgc tttccctaaa gacttcatgc aaagtacaga
     8341 ttcgaccatt cgtgttgggg ctaatgcaac ctatcagaca ccttggttgg ctgagttgac
     8401 tggtaactca cggatgaata ttggtatttt ctttgccatc attgccgttg cagttatttg
     8461 gttcatgctc aagaaaacaa ctcttggttt tgaaatccgt gcagttggtc ttaatccaca
     8521 tgcttcagaa tatgctggta tttctgccaa gcggactatt atcctatcta tgattatttc
     8581 aggtgccttg gcaggtcttg gtggagctgt tgaaggtttg ggaaccttcc agaacgtcta
     8641 tgttcaaggt tcgtcattag ctatcggatt taacggaatg gcggttagtt tgcttgcggc
     8701 caactcacca attggtatac tctttgcagc cttcctattt ggcgttctcc aagttggggc
     8761 tcctggtatg aatgctgcgc aggtaccatc tgagcttgtc agcattgtaa cagcgtctat
     8821 tatcttcttt gtcagtgttc attaccttat cgaacgcttt gttaaaccga aaaaacaagt
     8881 taaaggaggt aagtaaagat gtctattata accttgctcc ccctcttggt gtcttctatg
     8941 ctgatttact cagcacctct catctttaca agtatcggtg gtgttttctc tgaacgtggt
     9001 ggtgtggtaa acgttggcct tgaaggaatt atggttatgg gtgccttttc tggagttgtc
     9061 tttaaccttg aatttgcaga acaatttgga gcagcaactc catggctatc cttgcttgta
     9121 gcaggattgg ttggtagtgt tttctctatc atccacgcag cagcgacggt tcatttccgt
     9181 gcagaccatg ttgtcagcgg tacggtattg aacttgatgg cgcctgcctt ggctgttttc
     9241 ttagttaaag ttctttataa caaaggacaa accgacaacc taagtcaaac ttttggacgc
     9301 tttgatttcc cagtcttggc aaatatccca gtgattggtg atatcttctt caagtcaact
     9361 agtctacttg gttatctggc gattgccttc tcattccttg cttggtttat tctctttaag
     9421 actcaatttg gtcttcgtct ccgctctgtc ggtgaacatc ctcaagcagc ggataccttg
     9481 ggaatcaacg tctacaagat gagatattta gggattatta tttcaggttt tctaggtgga
     9541 attggcggag cgatttatgc gcaatcaatc tcagttaact tctcagtgac aactattgtt
     9601 ggacctggat ttatcgccct tgctgcgatg atctttggga aatggaatcc aatcggtgct
     9661 atgctttcta gtctcttctt tggactttca caaagtttgg ctgttatcgg ttctcaattg
     9721 ccgttcctac aaggagtgcc agcggtttat cttcaaattg caccttatgt tttgacaatt
     9781 cttgtcttag cagccttctt tggaaaagca gtcgcaccaa aagcagatgg tatcaactac
     9841 atcaaatcaa aataagcata caaaaaaacg tcagttcaat gactgaactg ccccccaaaa
     9901 gttagacaga aaaaatctaa cttttggggt gtttttatta tgaaactaac ttatgatgat
     9961 aaagttcaga tctatgaact tagaaaacaa ggatatagct tagagaagct ttcaaataaa
    10021 tttgggataa a
//
LOCUS       DAYYYC010000063         9774 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.063, whole genome shotgun sequence.
ACCESSION   DAYYYC010000063 DAYYYC010000000
VERSION     DAYYYC010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9774
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.063"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            218..1408
                     /locus_tag="ACHBV5_001872"
     CDS             218..1408
                     /locus_tag="ACHBV5_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HFM9967620.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(1729..2610)
                     /locus_tag="ACHBV5_001873"
     CDS             complement(1729..2610)
                     /locus_tag="ACHBV5_001873"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFM9967621.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(2749..4077)
                     /gene="vncS"
                     /locus_tag="ACHBV5_001874"
     CDS             complement(2749..4077)
                     /gene="vncS"
                     /locus_tag="ACHBV5_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HFM9967622.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(4074..4730)
                     /gene="vncR"
                     /locus_tag="ACHBV5_001875"
     CDS             complement(4074..4730)
                     /gene="vncR"
                     /locus_tag="ACHBV5_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HFM9967623.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(4779..4862)
                     /gene="pep27"
                     /locus_tag="ACHBV5_001876"
     CDS             complement(4779..4862)
                     /gene="pep27"
                     /locus_tag="ACHBV5_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HFM9967624.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(5042..6421)
                     /gene="vex3"
                     /locus_tag="ACHBV5_001877"
     CDS             complement(5042..6421)
                     /gene="vex3"
                     /locus_tag="ACHBV5_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HFM9967625.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(6473..7120)
                     /gene="vex2"
                     /locus_tag="ACHBV5_001878"
     CDS             complement(6473..7120)
                     /gene="vex2"
                     /locus_tag="ACHBV5_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HFM9967626.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(7133..8410)
                     /locus_tag="ACHBV5_001879"
     CDS             complement(7133..8410)
                     /locus_tag="ACHBV5_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9967627.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(8767..8937)
                     /locus_tag="ACHBV5_001880"
                     /pseudo
     CDS             complement(8767..8937)
                     /locus_tag="ACHBV5_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            complement(9223..9678)
                     /locus_tag="ACHBV5_001881"
     CDS             complement(9223..9678)
                     /locus_tag="ACHBV5_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967628.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
BASE COUNT         2786 a         2108 c         1806 g         3074 t
ORIGIN      
        1 gcaacctcaa aacagtgttt tgagcaactt gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt ataaacagcc actctccagt tcaattggag agttttttga tgagagtaga
      121 tatttataga cctcaatttg acaccataca ttttctatga taaaatgtaa caaatttatt
      181 tacaacaaat cgaaatctaa atgaaatgga attttctatg aaatcagtca aaggactact
      241 ctttatcata gctagtttta tcttgactct tttgacttgg atgaacactt ctccccaatt
      301 catgattcca ggactagctt taacaagcct atctctgact tttatcctag ccactcgtct
      361 cccactacta gaaagctggt ttcacagttt ggagaaggtc tacaccgtcc acaaattcac
      421 agcctttctc tcaatcatcc tactaatctt tcataacttt agtatgggcg gtttgtgggg
      481 ctctcgctta gctgctcaat ttggcaatct tgccatctat atctttgcca gcatcatcct
      541 tgtcgcctat ttaggcaaat acatccaata cgaagcttgg cgatggattc accgcctggt
      601 ttacctagcc tatattttag gactctttca catctacatg ataatgggca atcgtctcct
      661 tacatttaat cttctaagtt ttcttgttgg tagctatgcc cttttaggct tactagctgg
      721 tttttatatc atttttctat atcaaaagat ttccttcccc tatctaggga aaattaccca
      781 tctcaaacgc ttaaatcacg atactagaga aattcaaatc catcttagca gacctttcaa
      841 ctatcaatca ggacaatttg cctttctaaa gattttccaa gaaggctttg aaagtgctcc
      901 gcatcccttt tctatctcag gaggtcatgg tcaaactctt tactttactg ttaaaaattc
      961 aggcgaccat accaagaata tctatgataa tcttcaagcc ggcagcaaag taaccctaga
     1021 cagagcttac ggacacatga tcatagaaga aggacgagaa aatcaggttt ggattgctgg
     1081 aggtattggg atcaccccct tcatctctta catccgtgaa catcctattt tagataaaca
     1141 ggttcacttc tactatagct tccgtggaga tgaaaatgca gtctacctag atttactccg
     1201 taactatgct cagaaaaatc ctaattttga actccatcta atcgacagta caaaagacgg
     1261 ctatcttaat tttgaacaaa aagaagtgcc cgaacatgca accgtctata tgtgtggtcc
     1321 tatttctatg atgaaggcac ttgccaaaca gattaagaaa caaaatccaa aaacagagct
     1381 tatttacgaa ggattcaagt tcaaataagt aatcatactc tcctgggatt tcccaggaga
     1441 gttttttata gccaaatgaa ataagacagg aacgatggaa ttttggcatt caaatcaatt
     1501 gataagaatg ttttatagtg gagtgaaata ggatacgaac aaattgatta ggaaaatcaa
     1561 atgaatttat agaaatcttt tagcagttat gttgtcctat tctagtttca aaacgctata
     1621 gaagcagcat tgtgctagtc tagattcagt ttactatact aaaacgagta gcttgaaatc
     1681 aaaaaaccca ccctcacagg caggttttat ctgtattatt cagctagatt atgctttacc
     1741 ttctgaaccg aatacgtcga tacgttcttc aaccgatgct tggatagctt ttacaccgtc
     1801 agccaagaat ttacgtgggt cgaagagttt tttcttgtcg tattctgctt cgtttgcttc
     1861 gtagtcacga gcaaatttac gagttgcgtt agcgaatgcg atttggcatt ctgtgttaac
     1921 gttaactttg gcaacaccaa gtttgatagc tgcttggatt tgctcatcag gaatacctga
     1981 tccaccgtgc aatacgattg ggaatcctgg aagagcttct gtcaattttt gcaagtggtc
     2041 aaggtctaga ccttcccagt ttactgggta agggccgtgg atgttaccga taccagctgc
     2101 caagaagtcg ataccagttt caaccattgc tttagcgtct tcgattggag ccaattcacc
     2161 tttaccgatg attccgtctt cttcaccacc gatagtacca acttcagctt ctactgagat
     2221 acctttagcg tgtgcttttt caacaacttc tttagccaat ttaaggtttt cttcaactgg
     2281 aaggtgtgaa ccgtcaaaca tgattgaagt ataaccaact tcgatacact caagtgcatc
     2341 ttcgtagtga ccgtggtcaa ggtggatagc tactggtaca gtgataccca ttgattcaac
     2401 aaggttagcg atcaagttgc gagcaacttt gtaaccaccc atgtatttag cagcacccat
     2461 tgaagtttgg atcaaaactg gagctttttt agcttctgct gcgcgcaaga tagcttgagt
     2521 ccactcaagg ttgtttgtgt taaatccacc aactgcataa ccgttgtcac gggctgcttg
     2581 gacaaatttt tctgctgaaa cgattgccat tttatcaggc ctcctgtata tttttatggg
     2641 tcatcccatt tacattgttc attttatcac tttttgccaa aaaaatctag tttttcccgc
     2701 agtttcgatt gattttcttc taactccatc tatgtaaacc ctttctccct agtcttggac
     2761 gacttttgga aaatctataa agaaggttaa acgattctcc tccatctcga aacgataagc
     2821 taatttttca tgttctaata gactcttaac cacaaagagc cccataccag accccttgac
     2881 cttgcgacta gcattgtcag aaaaagactg ggctagtttt tcttgttcct ctgagctaca
     2941 gctattttcg ataaaaagtt ctccttctct ttctccaatt cgaactaagc cacctggaac
     3001 agagtgctta atggcattgc tgatgagatt agaaagaatc aacttcataa ctgatgggtt
     3061 tagataagcc tgctgatggg tcaaactatt gtctatctgg agctctcttt cctttgctag
     3121 caaggcataa tctttgacca gattttgcgt catctggagg aggtcaattg tttccctatc
     3181 atctcgcaat tcctgcacag aagagaggga aagtatctgc agaacatggt gattgagttc
     3241 atccacaatc cccaaggcaa ctcccagata ctggtctcta tccttataac gaccgatatt
     3301 ctctctcata ttttcgatta ggattttcaa actagccagc ggtgttttca attcatgaga
     3361 agctcctcgt aggaattcga ccttcatctt ctccagctgg agaatggctt cattcttttc
     3421 atgcaagtcc gcaataacag tcaagagatg ctggtagagg ctattgattt gttccttgag
     3481 attacctatc tcatccttag aatccacgcg caatcgcact tgggaatcca ggtccatcat
     3541 ccgacgggtc acccgcttga tttccaaaat cggtgcaaca atagtccgag cgtagatgta
     3601 ggccaccaag agggaaatca gaaaggaggc cagcaaggta tagggaagaa actggagact
     3661 gatttgctcc gcttcctttt gtaaatccat ggaagctaga aactggagaa tcatagtacc
     3721 accgtcttgc gttttcacct cgcgctcctc aataaagaga gaggttgtct ggcggtctgt
     3781 gtccagagga agactgtcct tgacttctaa cttgtcctcg gtcatctcac ctttgacggt
     3841 ccccttgata tcactagtct gggaatacaa gtctaacact tgctcgatac tctgcctatc
     3901 tttcccttct agggactggg caatggctgt tgccttttga ccaatggttt cctgacgatg
     3961 actcagataa gtcgaaggaa aaagaaaata aatagctaaa tgaaggcaga taaccagaac
     4021 actaaatatc gagaaggtat agataaatat ctttgcaaat aaacctgttc gtttcatttt
     4081 cgctccaatt tataaccaac attgcgcaca gtgaggatac aatccaagtc tagctttttc
     4141 cgcaattcct tgatataaac atcaataaca cggtcaaagg gaacctcatc tgtcgctttc
     4201 cagacggcat cgataatctg agatcgagtc aaggcccggc cttcattttt cactagatag
     4261 tccagaattt ccaactcttt ggcattgata ggcacttctt gacctgcgag gcttgcactg
     4321 tagctttcaa agtccacctt ggtatccttg taagaaaaga ttcgtcctgt atcgtagtag
     4381 cgcttgaaaa tcgcgtccac cctcactttt aaaagggaga gggagaaagg tttttccaga
     4441 tagccatctg ccaaagaggc aaaggcactc atcttgtatt cctcatcttg aaaagctgtc
     4501 aacatcaaga caggaacctg actggtttta cgaatctcag ctaggacttc taagccgttg
     4561 agcttgggca tctggatatc cagtaaaacc agggccacct catagctaga aaattgctcc
     4621 agagcttcct gaccgtccgc tgcctcaata gtttcatagc cacaatccgt caaataatca
     4681 ctgaccccct cacggatcat ctcttcatct tctacaatta aaattttcat actttaactg
     4741 ctctctattt tttatttttc ttagaataaa tacctaccct attttctatt atagtctctt
     4801 gctggccttt tgtctgcaag caactgacca ctagataaaa cgttgtgaaa ttcctttctc
     4861 ataaattcca taactttagt atattatatt taagcactaa agtacaaaga aagcaactga
     4921 aagcaatgat tttcaccact gctttcggat ttattttgaa ttgttaaata gccattccta
     4981 tccactattc ttgaatagaa acacaagatg caatctttat tctagactca ttttttcaaa
     5041 tttattcacc atccagcaag agctcttttg gttgttttct aaggagattg cttgaagcaa
     5101 gcgccataac gagaaccact agaaccaagg caaggacaaa aatgatgata aagtctgatg
     5161 tctgaatgga aatgtctagg ctcgacaagg tcttgctaaa gccatctact tctgcaccac
     5221 caccaaggtt agaggcttga gccgccttac tagcctgttt ggcaacacct gaagtcacat
     5281 tggcaaggac agtgtttcca attgcacggg cagtgtaatt agctaggaag taagcagaaa
     5341 ctagagcagg gatagcaatc aagatagatt cggtgatgaa ttgacccaag atacttgcct
     5401 gcttgaggcc gatagagagg agaattccca cttccttgcg acgggcgttg atccaaaggc
     5461 tgagcaagag ggcaaggagg agaactgaga agctcaagct accccagaag aggaggttgg
     5521 ccatcttgta cataccagag atagattgct caagagctgg gtagttagag gagctcttga
     5581 cgagtgtgta gctcttccag ttgataccac tgatgccatt caactctttc ataacatcat
     5641 ccaagttctt gtctgctgtt acaaagaagg ttgcgtcccc ataaatggct gtgtcttctg
     5701 tgtatccata aagttttgca gcagtgtgaa tgtctgtaat agctgtgttt tcgtaaagtt
     5761 cttgtgagta ggttactgct gacttattat gaccatcaaa gagtcccttg attgtcactt
     5821 caactgtttc cttggctcct ttttcattat ctgcatcgta gatattagag tccagtttaa
     5881 ccttgtcccc tactttccag ccgtgtttgg ctgccaagtc cttgtgcaag aggattttat
     5941 ccttgtcgtc gttggttaag tgctctcctt cgactagttt ataagaacca gagacaaact
     6001 tgtcttcttt agaggagtca ttgacacctg taatcatcaa gctacttcca aaacgcttgg
     6061 cacgatcagc agtgagattc ttcttggttt ctggcgtttc aatcaggtca tatccagtca
     6121 aatctccgat agcgttgata cgtttgacat aagactcaat ggccttgttt tcggtgattt
     6181 ttttgatgtc ttcacccttg atattcccag caccacgagg cgttccttgg ttgacgcgac
     6241 gattgatttg catggagaag ctattggtga tatttttaaa ggtctcctga gaagccttgg
     6301 cagtagctcc cttgattgac aagccgacca aactcaagct cgccatgagg agaataatca
     6361 ggaagatgac aatcgatttg aaaaacttcc ttgtaacata ggcaaatgcg ttgtgtaaca
     6421 tagattccct ttctagattt tgttttaatc attctattaa aataagctca aattatttac
     6481 tagtattgcg cgtttcagtc agtttcttat cctttaattc aagtgtaata tctgacgctt
     6541 gtgccacttc tttactgtga gttacgacaa tcacacattt acctgttttc tgggcaagtg
     6601 atttgagtag ttcgacaata tctccagcag ttttaggatc cagatttcct gttggctcat
     6661 cagctagaat aactggagct tctgagacca aactgcgagc aatggcaaca cgttgctgtt
     6721 gaccacctga taactggaga acattccgct tgatctggct ttcatccaaa ccaagctcaa
     6781 gaagtgtatt cttgcttgcc tttttgttga ccaatcggat attttccagc ggagaaagat
     6841 aatctatcaa gttataattt tgaaagacca gggaaatatg gtgcatgcga tggtaagaat
     6901 agcccttctt acgaatatcc tctccttgaa aaaggataga accttcaaca ggactatcta
     6961 gaccagcaag tagggacaag agtgtggatt ttcctgctcc tgactcccca ataatactgt
     7021 aaaattttcc gggttcaaaa ttataattga tctgatatag gactgcttca gcagtattct
     7081 tataacggta ggtaacatct tgtaattgta ataaagtcat gatttctcct tcttaactaa
     7141 tagatgataa aatttctttc ggtgattttc taaataagaa taggaaacaa agggctacag
     7201 ataagcaact aagcagaact agaaaaacat aggattctgc aaaagataag atgctagttg
     7261 ataaactgct tgctttggct agtgtatctt gtaagcttgc ctgatctcca cttgctagta
     7321 gagtttggag taggtaagtt gtgattgcgt ttcctgcaac aaatgctgga agcaaagctc
     7381 caagagatac caaaactacc tctaaacaga attgtaggaa gatcgagctc ttgccttttc
     7441 caagtgcaag taaaatcccc acttcataga cccgttctct caaccagaga gacaaaacca
     7501 gaattaaggc tccagctcct gctatcaaca tcccataaag gaagatggtc aggaaggttt
     7561 ggaaagttgc aactgagtct ttgatttgtt caaaagcctt gttttccttt tcgacttggt
     7621 agccttgatt ttccaaggcc aagttttcta cctgcttcat gagtccgtcc atttccttag
     7681 gattttctac atagaagcgt gctgcactga cttgagcttc actattgccc aaaagggttt
     7741 ggctactttc atagtctgta aagacttgat tttcactgaa gtcagaagac aagcctgtga
     7801 atttctcttg ttttttacca gaaaagatgc cgataatctc aaactctact gtttgtcctt
     7861 ttccagattc agactgacca gcatccaagc caatcttgtc atgaagcgaa agaccgttct
     7921 tcttagccaa ttcttcgtgg ataaggattt tcttggaatc ccctttttga aggtgtcgcc
     7981 cttcttttag attgaaagcc gaactggtaa aggttacatc cttggatgaa tcctcaagag
     8041 ccgttaagct aaccaagtta ttgtctgcag ctgataaatc atcacgctcc acgctctgct
     8101 cgccagtcac tgcttccttg tcttttagtt ttgcgaccgt ctcaagttca ggagagacat
     8161 tttccagccc cttaatcttg cttacagatg ctaggtctga caacttgaat gtctgaccat
     8221 tctctatctt cttaatagaa aaagatgtat tgagtgattt ataaagattg ctttctactg
     8281 ttttgttgga cttcatcaga gtcaaacagg ctgaaattcc ggccaataag accaataaaa
     8341 tcagaaataa aataaaactt ctcagtcgct ttctgctgac ataagcccaa gatctttgga
     8401 ttggattcat ttgtcacctc catatttgta agactattat aaaacccaaa tatgaaatgt
     8461 ttatgaaata cgaaaaaaaa atatcgagta ggggataatc tctagcccct ctcacaccac
     8521 catacgtgcc gttcggcata cggcggttca actaactttt aacgcatgtc gttcaaggta
     8581 ataatccaaa cacgaaacca gtccacgttt ttcaaggact ggttttgata tagcacgttt
     8641 aagtaccgac ttctgagcta ctatagtata ttgaaactag aatagtacac ctctacttct
     8701 aaaatattgt tagaaatcga tttgactgtc ctgaacgatt cgtcctattc ttatttcatt
     8761 ttactataat tgatagtggt cgccccagcc agatacctta tctgctatcc atttaggaac
     8821 ccctaactta agcaatcccc ataatcgtct cgatttcttc ttccattgct tccagataat
     8881 cactcgtagg cgagtacgca agcgctcatc tatgctagtg actatacttt tcatatttat
     8941 aattcattcc tttcgtttca ctcaaggcac aacacagaat gaaaaagtgt tgtgatcttt
     9001 attttgtttt ataataatag tgagaaagcc tatcactact acaaatcacg gggaggtgaa
     9061 taagtgagtg gtacagccac tacctcgcat attttgtcac atcatttaac ggtacataat
     9121 aagttgtacc atctgaataa gttgctacaa tatcatttgc atgctctcct tcacctttag
     9181 caaaggttgg agctcctgct ggatgatttt tatttgcctc tttcaatttt tcaataatgg
     9241 cattttttct gtatctttta tattatcagg atttttcact aagattttgt ctggatatgt
     9301 cggtttagca gaaacaattt ttactgttat ttctttttta ttcgaagcac ttgtccagtt
     9361 tccagcatta tctttagcat ttaattttac agtaattcct gaactaggaa cttcagtagc
     9421 aggttgatta tcaacattat tcaactttaa tttcaaaaga gctgttgcat cagacgtttt
     9481 atcaatcgtt atatataatg atgaattgtt attataacca gtttcttcat atttagctgt
     9541 ttgtgagcta cttgaaacag aactgaaatt atgcccacta cctccctgat tatcttcaat
     9601 gcttacgtct aaatgaactt ccccactatt atttggctta gcaacaactg ttatagtaaa
     9661 ataacataaa atttgcataa atagattagg taaatcaaag caacttctag gaatgtttta
     9721 gcagtcacag tgtactttcc cagcatcaag ccactataac tctgcacata aaaa
//
LOCUS       DAYYYC010000064         9702 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.064, whole genome shotgun sequence.
ACCESSION   DAYYYC010000064 DAYYYC010000000
VERSION     DAYYYC010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9702
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.064"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            100..597
                     /locus_tag="ACHBV5_001882"
     CDS             100..597
                     /locus_tag="ACHBV5_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFM9967629.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            597..2252
                     /gene="dnaX"
                     /locus_tag="ACHBV5_001883"
     CDS             597..2252
                     /gene="dnaX"
                     /locus_tag="ACHBV5_001883"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFM9967630.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATDKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2280..2474
                     /locus_tag="ACHBV5_001884"
     CDS             2280..2474
                     /locus_tag="ACHBV5_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HFM9967631.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2624..3394
                     /gene="sufC"
                     /locus_tag="ACHBV5_001885"
     CDS             2624..3394
                     /gene="sufC"
                     /locus_tag="ACHBV5_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFM9967632.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3422..4684
                     /gene="sufD"
                     /locus_tag="ACHBV5_001886"
     CDS             3422..4684
                     /gene="sufD"
                     /locus_tag="ACHBV5_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFM9967633.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4695..5921
                     /locus_tag="ACHBV5_001887"
     CDS             4695..5921
                     /locus_tag="ACHBV5_001887"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFM9967634.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATAFYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVINPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5908..6348
                     /gene="sufU"
                     /locus_tag="ACHBV5_001888"
     CDS             5908..6348
                     /gene="sufU"
                     /locus_tag="ACHBV5_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFM9967635.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6402..7814
                     /gene="sufB"
                     /locus_tag="ACHBV5_001889"
     CDS             6402..7814
                     /gene="sufB"
                     /locus_tag="ACHBV5_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFM9967636.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8045..9286)
                     /gene="pbp3"
                     /locus_tag="ACHBV5_001890"
     CDS             complement(8045..9286)
                     /gene="pbp3"
                     /locus_tag="ACHBV5_001890"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HFM9967637.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9389..>9702
                     /gene="cozE"
                     /locus_tag="ACHBV5_001891"
     CDS             9389..>9702
                     /gene="cozE"
                     /locus_tag="ACHBV5_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HFM9967638.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LI"
BASE COUNT         2868 a         1806 c         2142 g         2886 t
ORIGIN      
        1 ggggttaccc actacaaata ttatagagcc caaaatcctt tgtttactaa acaagggatt
       61 tttcttttgt ctctgctcct tttttgatat aatagttcta tgttaaaatc agaaaaacaa
      121 tcacgttatc aaatgttaaa tgaagaattg tccttcctat tggaaggcga aaccaatgtt
      181 ttggctaatc tttccaacgc cagtgctctc ataaaatcac gttttcctaa taccgtattt
      241 gcaggctttt atttgttcga tggaaaggaa ttggttttag gccccttcca aggaggtgtt
      301 tcctgcatcc gtattgcact aggcaagggt gtttgtggtg aggcagctca ctttcaggaa
      361 actgttattg ttggagatgt gacgacctat ctcaactata tttcttgtga tagtctagct
      421 aaaagtgaaa ttgtggtgcc gatgatgaag aatggtcagt tacttggagt tctggatctg
      481 gattcttcag agattgagga ttacgatgct atggatcgag attatttgga acaatttgtc
      541 gctattttgc ttgaaaagac aacatgggac tttacgatgt ttgaggaaaa atcttaatgt
      601 atcaagcact ttatcgaaaa tatagaagtc aaaacttctc ccagttagtt ggtcaagaag
      661 ttgtggctaa gactcttaaa caagcggtgg agcaagagaa aataagtcac gcttatcttt
      721 tttctggtcc tcgtggaacg ggaaaaacca gtgttgctaa aatctttgcc aaggctatga
      781 actgtcccaa tcaagtgggt ggcgaacctt gcaataactg ctatatttgt caagcagtga
      841 cggacggtag tttagaagat gtcattgaaa tggatgcagc ttctaataat ggggtagatg
      901 aaattcgcga aattcgtgat aaatctacct atgcgcctag ccttgctcgt tataaggttt
      961 atatcataga tgaggttcac atgctgtcta caggggcttt taatgccctc ctaaagacgc
     1021 tggaagaacc aacacagaat gtagtcttta ttttggccac tactgaattg cacaagattc
     1081 ctgctactat tctatcccgt gtgcaacgtt ttgagtttaa atcaattaag acacaggata
     1141 ttaaggaaca tattcactat atcttagaaa aagaaaatat cagttctgaa ccagaggctg
     1201 tggaaatcat tgccagacgg gcggaaggtg gaatgcggga cgccttgtct attttggatc
     1261 aagccctgag tttgacacag ggaaatgagc tgacgactgc tatctctgaa gaaattactg
     1321 gcaccattag cctatcagcc ttggatgatt atgtggcggc cttgtctcaa caggatgttc
     1381 ccaaagcttt gtcttgcttg aatcttcttt ttgacaatgg taagagcatg actcgttttg
     1441 tgaccgatct tttgcactat ttaagagact tgttaattgt tcaaacaggg ggagaaaata
     1501 ctcatcatag ttcagtcttt gtagaaaatt tggcacttcc tcaaaaaaat ctgtttgaaa
     1561 tgattcgctt agcaacagtg agtttagcag atattaagtc tagtttgcag cccaagattt
     1621 atgctgaaat gatgaccgtc cgtttggcgg aaatcaagcc cgaaccagct ctatcaggag
     1681 cggttgaaaa tgaaattgct acgctgagac aggaagttgc ccgtctcaaa caagagcttt
     1741 ctaatgtagg tgcggttcct aaacaagttg caccagctcc tagtcgacca gctacggaca
     1801 aaacagtcta tcgtgtcgat cgcaataaag tgcaatctat cttacaagag gccgtcgaaa
     1861 atcctgattt agcacgtcaa aatctaattc gtttgcagaa tgcctgggga gaggtaattg
     1921 aaagtctagg tgggccggac aaggctctgc tagttggttc tcaaccggtt gctgccaatg
     1981 aacaccatgc tattcttgct tttgagtcta acttcaatgc tggtcaaact atgaaacgag
     2041 acaatctcaa taccatgttt ggtaatatcc tcagtcaggc ggcaggtttt tcacctgaga
     2101 ttttagctat ttccatggag gaatggaaag aagttcgcgc agccttttca gccaaagcca
     2161 aatcttctca aactgaaaaa gaagtagaag aaagcctgat tccagaagga tttgaatttt
     2221 tggctgataa agtgaaggta gaggaagact aaagaaagat ttcatgatac aataagttta
     2281 tgaataaaca acaatttatt attatggcgc tgtttacagc tgctgagacc tattttttca
     2341 atgaagcctg gatgactggc cgctatatta tggcagcctt ttgggcaatt ttactcttta
     2401 gaaatttccg agtcagttat gtgatgggca aaatcgttga tgtcatcgat cagcatttta
     2461 ataggaaaga ctagccctca gcttccagac aaaatcaaag ccttttaggc ttttttttgt
     2521 tatactagaa aagtatattt atagaatttt tgctctattt ctggggaaat cagacgtttt
     2581 tctagtaagt actgtaaaag ttttgaaaaa gaaaggaact atcatgtcag tattagagat
     2641 taaagatctt cacgttgaga ttgaaggaaa agaaatttta aaaggggtta acctgaccct
     2701 gaaaacagga gaaattgccg ctatcatggg accaaatggt acaggtaaat cgactctttc
     2761 tgccgctatc atgggaaatc caaactatga agtaactaaa ggtgaagttt tgtttgatgg
     2821 cgtaaacatc cttgagttgg aagtggatga gcgtgcgcgt atgggacttt tccttgctat
     2881 gcaataccca tcagaaatcc ctggaattac caatgctgag tttcttcgtg ccgctatgaa
     2941 tgcgggtaaa gaagatgatg agaagatttc agttcgtgag tttattacta agctagatga
     3001 aaaaatggaa ttgctcaaca tgaaagaaga aatggcagag cgttacctca acgaaggctt
     3061 ctctggtggt gagaaaaaac gcaatgaaat tcttcaactt ttgatgttgg agccaacatt
     3121 tgctcttttg gacgagattg actcaggtct tgatattgac gctcttaaag ttgtgtctaa
     3181 aggtgtcaat gccatgcgtg gtgaaggttt tggtgctatg atcatcactc actaccaacg
     3241 tcttttgaac tatatcacac ctgatgtggt acacgtgatg atggaaggtc gtgttgtcct
     3301 ttctggtggt ccagaattgg ctgcgcgttt ggaacgtgaa ggatacgcaa aattagctga
     3361 agaacttggc tacgactaca aggaagaatt gtaatttcct cgtatctttt aggagaagta
     3421 aatgactaga gaaaatatta aacttttttc agaaatgcac gctgaaccaa gctggttggc
     3481 tgatctccgt caaaaagctt ttgacaagat tgagactttg gaattaccag ttattgagcg
     3541 tgtcaaattc caccgttgga atctgggtga tggaacgatt acagaaaatg agccatcagc
     3601 aaatgttcca gatttcacag ctttagatca tcacttgaag ttggtgcaag taggaactca
     3661 aactgttttc gaacaaactc cagttgagtt agctgaacag ggtgttgtct tcacagactt
     3721 tcactcagct ttagaagaaa ttccagagct gatcgaagaa ttcttcatgt catctgttaa
     3781 gtatgatgat gacaagttgg cggcttacca cacagcttac tttaacagtg gtgctgtact
     3841 ctatattcca gataacgtag aaatcacaga gccaattgaa ggaattttct accaagatag
     3901 cgatagcaat gtgccgttta acaagcatat tatgattatc gctggtaaaa attctaagat
     3961 tagttatctg gagcgtttag agtcacgcgg tgaaggaagt gacaaagtaa ctgccaatat
     4021 cacagtggaa gtgattgcac gttctggtgc gcaagtcaag tttgctgcta tcgaccgtct
     4081 aggtgaaaac gtcactgcct acattagccg tcgtggtaaa ttaggcaacg atgcaagtat
     4141 tgactgggct atcggtgtca tgaacgaagg aaatgtcgtt gctgattttg atagtgactt
     4201 gattggtaat ggtagccatg ctgacctcaa ggttgtagct ctttcaagtg gtcgtcaggt
     4261 acaagggatt gatactcgtg taactaacta tggctgcaac tctatcggaa atatcctaca
     4321 acatggggtt atccttgaaa aagcaacttt gactttcaat ggtatcggcc acatcatcaa
     4381 gggtgctaag ggagcagatg cgcaacaaga gagccgtgtt ctcatgcttt cagaccaagc
     4441 gcgttcagat gctaacccaa ttcttttgat tgatgaaaat gatgtcactg caggacacgc
     4501 agcgtctatc ggacaagttg atccagaaga catgtattac ctcatgagtc gtggattgga
     4561 taaggcaact gcagagcgtt tggttgttcg tggtttcctt ggatctgtta tcgtggagat
     4621 tccagtcaag gaagttcgtg atgaaatgat tgcaactatc gaagagaaat tgtcaaaacg
     4681 ctaaggggaa gcctatgtta gatgtagaag cgattcgcaa ggattttcca attttagatc
     4741 agattgtcaa tgatgaacct ctggtctatc tggacaatgc tgcgacgaca caaaaacccc
     4801 tagtagttct gaaagctatt aacagttact atgagcagga caatgccaat gttcaccgtg
     4861 gtgtccatac cttagcggaa cgagcgacag ctttttatga agctgctcgt gaaaccattc
     4921 gtaagtttat taatgcaggc tctacaaagg aagttctctt taccagagga acgacaacca
     4981 gccttaactg ggtggcacgc tttgctgagg aaattctcac tgagggagac caggtcttga
     5041 tttcagtaat ggaacaccat tctaatatca ttccatggca ggaagcttgt cgaaagactg
     5101 gagcagagct tgtctatgtc tatcttaaag acggtgcctt ggatatggag gatttgcgag
     5161 ctaaattgac tgataaggtt aaatttgttt ccctagctca tgcctccaat gttcttggtg
     5221 tgatcaatcc gatcaaggaa atcactcaat tagcccacca agttggggca atcatggtag
     5281 tggatggtgc tcaatctaca cctcatatga agattgatgt ccaggacttg gatctggact
     5341 ttttcgcctt ttcgggtcac aagatggctg gtccgactgg tatcggtgtc ctttacggca
     5401 aagaaaagta tcttgagcaa atgtctccag tagaatttgg cggcgagatg attgattttg
     5461 tctacgagca atttgctagt tggaaggaat tgccttggaa atttgaggct ggaacgccaa
     5521 atatggcagg agctattgga cttgcgactg cagttgatta tttggaaaag attggtatgg
     5581 atgccgttga agctcatgaa caggaattga ttgcgtacgt ctatccaaaa ctgcaggcaa
     5641 ttgagggatt gaccatttac ggttctcagg atttggctca acgttcgggt gttattgcct
     5701 ttaacctagg tgatctccat cctcacgatc ttgcgacggc tctggattat gaaggagtgg
     5761 ctgttcgtgc tggtcaccat tgtgcgcaac ccttgcttca gtatttggaa gtcccagcaa
     5821 cagctcgtgc aagtttttat atctacaata ccaaggcaga ttgcgacaaa ctagtcgatg
     5881 ccctacaaaa gacaaaggag tttttcaatg gcactttcta aactagatag cctttatatg
     5941 gcagtggtag cagaccattc gaaaaatcca catcaccaag ggaagttaga agatgctgag
     6001 caaatcagtc tcaacaatcc gacttgtggg gatgtcatca acctctctgt caagtttgat
     6061 gcagaggacc gtttggaaga tattgctttt ctaaattcag gatgcacgat ttcaactgct
     6121 tctgctagta tgatgacaga tgccgtttta ggaaaaacca aacaagaaat tttagaactg
     6181 gcgactattt tttctgaaat ggttcaaggg caaaaagatg agcgtcaagg ccaacttgga
     6241 gacgcggcat tcttgtcagg tgttgccaaa ttccctcaaa gaatcaagtg tgcaacccta
     6301 gcttggaatg cccttaagaa aacaattgaa aatcaagaaa aacagtaaga caagtttctt
     6361 ttgtcttatg aattattaga aatgaagaaa gaaaggatac tatggctgaa gaaagagtag
     6421 aaccaaaacc aattgacctt ggtgaatata aatttggttt ccatgacgat gtagagcctg
     6481 tcttatcgac aggaaaagga ctcaacgaag gtgttattcg tgaattatct gctgctaagg
     6541 gtgagcctga gtggatgttg gagttccgtt tgaagtctta tgaaaccttc aaaaaaatgc
     6601 ccatgcaaac ttggggagca gacttgtcag agattgactt tgatgactta atctactacc
     6661 aaaaaccatc tgacaaacca gcccgttctt gggatgatgt acctgaaaag attaaagaaa
     6721 cctttgaacg tatcgggatt ccagaagctg aacgtgctta tttagcaggg gcttctgccc
     6781 agtacgagtc agaagtggtt taccacaaca tgaaggaaga gttccaaaaa ttaggtatta
     6841 tctttacaga tacagattcc gcactcaagg aatacccaga cttatttaaa caatactttg
     6901 cgaagttggt accgccgaca gataacaagt tggcagccct caactcagca gtatggtcgg
     6961 gtggaacttt tatctacgtg ccaaaaggtg tcaaggtaga tattccactt caaacttatt
     7021 tccgtatcaa taacgaaaat ataggtcagt tcgaacgtac cttgattatc gttgatgagg
     7081 gagcaagcgt ccactacgta gaaggatgta cagcaccaac atattcaagc aatagcttac
     7141 acgctgccat tgtagaaatt tttgctttgg acggagctta tatgcgttat acaactatcc
     7201 aaaactggtc tgataacgtc tataacttgg taacaaagcg tgctaaggct caaaaggatg
     7261 ccactgttga gtggattgat ggaaacttgg gtgccaaaac gactatgaaa tatccatctg
     7321 tttaccttga tggagaagga gcgcgtggta ccatgctctc tatcgccttt gctaatgcag
     7381 ggcaacacca agacacgggt gctaagatga ttcacaatgc tccacatacc agctcgtcta
     7441 ttgtgtctaa atccatcgct aaaggtggag gaaaggttga ctaccgtgga caagtcacct
     7501 ttaacaagaa ctctaagaaa tctgtttccc acattgaatg tgataccatt atcatggatg
     7561 acttgtcagc atcagatact attccattta atgaaattca caactcgcaa gtggctttgg
     7621 aacacgaagc caaagtatct aagatttcag aagagcaatt gtattatctc atgagccgtg
     7681 gattgtcaga atctgaggca actgaaatga ttgtcatggg atttgtagaa ccctttacaa
     7741 aagaacttcc aatggaatac gcagttgagc tgaaccgctt gattagctat gaaatggagg
     7801 gatcagttgg ataaaatttg attttatact cttcgaaaat ctcttcaaac cacgtcagca
     7861 tcgccttacc gtatgtatgg ttactgactt cgtcagtttc atctacaacc tcaaaacagt
     7921 gttttgagca agctgcggct agcttcctag tttgttcttt gattttgagt attagattta
     7981 ctcaaaatca aggattttga agatgaactt gtatcaaaaa atcgcggttt aaaatcgcga
     8041 ttttttataa tttctcgtta acaaagcgga caaactgatt ccaccaaact tttaagaaga
     8101 aggctttttc aattttcttg tctgctacca tttcgaaact agggcgctct gtggtgatgt
     8161 aaccttgacc aatcaagtcc ttgtcttcat aagtcaaatg gccaaccact gttccagctt
     8221 caagtggtgc tgggattgct ttggaatcag gtgtgaattg aacagattgg gaagattgat
     8281 tcccaacacg ttcgattaga tagatatcct ctggagccac tgcagttact gtatcttctt
     8341 ttccatcttg tacaggggtt ttgctatctt gataggcatc gccttgttga acgattttgc
     8401 gaagtgtaaa tgtagaagaa atataatcca ttagggaaga tgtagctgta aatcgagcgt
     8461 aaggattatt gtcttgatga tctgcattta aaacaactgt gatgactctc atgccttttt
     8521 cgacagtagt accaacaaaa gactctccag ccttatctgt tgttcctgtt tttagcccat
     8581 caaaaccacc acggtaagca ggcatacctt ctaacatgta gttggttgaa gtgattgtca
     8641 tcccagcaaa agtagaagaa ggttttttgg tgatttctaa gacttgtggg tattttttga
     8701 tgaggttgcg agcaacgata gcgacatcat aagcactaag cttattttcc tcatcttttt
     8761 tagaacctgg gtaaatgtta tcccctagag tttcattgtt aagacctgtc gtattgacaa
     8821 cagtggcatc ctgaattccc cattccaaga gttttgcccg catcatatcg acgaaatctt
     8881 tttctgagcc agcaattttc tcagctaggg caatagcggc gctgttggca ctagatacca
     8941 gagttgcttc aagcaactct tcgacagtat aattacgggc ctccatagga atattactgg
     9001 cttcagaatt tgtcgtcaat tgataaggat aatcagaaat atctacagga gtggagaggg
     9061 taatacttcc gttttccaaa gcttcataga ccagataaac agtaatcaat tttgttatgg
     9121 aagcaatttc gacaggttgc gttgcatcct tctcatagag aattttacca gtatttgcct
     9181 caacagcaat cgcatgttta gcggcaatgg taaaatcttg agcaacagca gtagaagcac
     9241 cccctaaaag agagacagtt aacaaagtta aaaatatttt tttcatagta gtcttattct
     9301 atcataaaga aaaaaaatat tcttgcttta ataattcatc tgttaagctt tttgaaaata
     9361 tggtaaaata aagtgaggga ggtaactcat gtttcgtaga aataaattat ttttttggac
     9421 cacagaaatt ttactcttaa ccatcatctt ttacctatgg agacagatgg gatctttgat
     9481 taaccctttt gttagcgtgc ttaatacaat tatgattcca tttttattag ggggctttct
     9541 ttattatttg acaaacccta ttgttacttt cttaaataaa gtctgtaaac tcaatcgttt
     9601 gcttggtatt ttaattacct tgtgtacttt ggtctgggga atggtcatag gtgttgtcta
     9661 tctcttacct attttgatta atcagttatc tagtttgatt at
//
LOCUS       DAYYYC010000065         9358 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.065, whole genome shotgun sequence.
ACCESSION   DAYYYC010000065 DAYYYC010000000
VERSION     DAYYYC010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9358
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.065"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            1..656
                     /locus_tag="ACHBV5_001892"
                     /pseudo
     CDS             1..656
                     /locus_tag="ACHBV5_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612110.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            653..871
                     /locus_tag="ACHBV5_001893"
     CDS             653..871
                     /locus_tag="ACHBV5_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967639.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETKPTDESGT"
     gene            complement(928..1170)
                     /locus_tag="ACHBV5_001894"
     CDS             complement(928..1170)
                     /locus_tag="ACHBV5_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFM9967640.1"
                     /translation="MKKDIHPEYRPVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(1266..2201)
                     /locus_tag="ACHBV5_001895"
     CDS             complement(1266..2201)
                     /locus_tag="ACHBV5_001895"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFM9967641.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            2305..2748
                     /locus_tag="ACHBV5_001896"
     CDS             2305..2748
                     /locus_tag="ACHBV5_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFM9967642.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSIGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVV"
     gene            2864..3130
                     /locus_tag="ACHBV5_001897"
     CDS             2864..3130
                     /locus_tag="ACHBV5_001897"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFM9967643.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            3127..3501
                     /gene="crcB"
                     /locus_tag="ACHBV5_001898"
     CDS             3127..3501
                     /gene="crcB"
                     /locus_tag="ACHBV5_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HFM9967644.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            3495..3824
                     /gene="crcB"
                     /locus_tag="ACHBV5_001899"
     CDS             3495..3824
                     /gene="crcB"
                     /locus_tag="ACHBV5_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HFM9967645.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            3943..4290
                     /gene="rplS"
                     /locus_tag="ACHBV5_001900"
     CDS             3943..4290
                     /gene="rplS"
                     /locus_tag="ACHBV5_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFM9967646.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            4332..4403
                     /locus_tag="ACHBV5_001901"
     tRNA            4332..4403
                     /locus_tag="ACHBV5_001901"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4365..4367,aa:Arg,seq:cct)
     gene            complement(4969..5823)
                     /locus_tag="ACHBV5_001902"
     CDS             complement(4969..5823)
                     /locus_tag="ACHBV5_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM9967647.1"
                     /translation="MENFGAVLKDIRISKNFRLKDLSCNEISESTISRFENGITKLSI
                     NHFYILLNRLGISFSEFEELVHCYYSKKECLFEELEHAVNSSDIFLLQELVDKIELKQ
                     KQEKSLCNYHIKLIAEQQINRLANLPYNSSKCNELIKYLLSVDTWMEYELKLFYNSVF
                     FMNTRTISLLYRIVIKKTRYFLKTNTGTHRIIPLYLFNLKLLLKNNLLGSAQFFIDDL
                     ENLLTRQGYYFEKNYLLFLKGIYLIKTNQIELGKKECSKAMRIFKEYNDSDTINELNQ
                     KFKLDLTI"
     gene            5917..7137
                     /locus_tag="ACHBV5_001903"
     CDS             5917..7137
                     /locus_tag="ACHBV5_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004197 - cysteine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HFM9967648.1"
                     /translation="MKKILLSTVALLSLVASLLANNPVSAQESSSQATYSKSSGSWIK
                     SGNRWWYKHSDGSYTTNGWEKINGTWYYFDSEGWMKTGWIKEYGKWYYLDDSGAMKTG
                     WCLVSGSWYYLNSSGVMQTGLQTINGKQYYLAAGGAMQTGWHNIGDDTYFFANSGENQ
                     NINRRALVLGETSTRAVPIADVNAMEKVFNNQNFSEVVRFPDRTKSEIIAKMQELFES
                     SSEGDVNYLYFTCHGGRDGRIYIGSDGLAFSGWELASVLKQYKGKFVVMLDCCHAGTI
                     ISKDNTGEGNEGASTEYFDLDEFVSGFSNMDGNEKSGEMIDSKFLVLCSSRGAEYSSG
                     GSLSLATKYWSLGSGWNPLQNSQAYLAADQNNNRRITLNELYTYSREQVLKQNSNQHI
                     EVYPDNSQFVLFKK"
     gene            7150..8331
                     /locus_tag="ACHBV5_001904"
     CDS             7150..8331
                     /locus_tag="ACHBV5_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HFM9967649.1"
                     /translation="MKVSKKITLFSLSFAGFVLLTLPQAGKAFELKEDWAFKGGIRYE
                     NGKVSKINNGYEVNIKVLDLPSTSAIEWTVRLNGEKQNTNFLAEERTVSKTEDKGRFL
                     HFYIPYGYRGDIVVEAKSGNEVKTWSTKVVDDVYSDSAKSGYFILDGEQILESSWDSV
                     NESYIATLPTVTSGKTVVAWREKGTLNLIKPGRIARQYNSSGSYVELSPIFETASWLK
                     SNQNWYYQKQGQLVQNSWIKDQGSWYFMDDEGVMFNQTWLHQGGSWYAFKSSGAMISA
                     DWLYDNGSWYYLKDSGSMVTGWLKNGGSWYYLNKSGSMATGWIKDSGTWYYLKNSGSM
                     ATGWVKDSGSWYYLKNSGSMATGWVKDNGKWYYLASSGNMLRNTRTPDGYYVDGSGAW
                     K"
     gene            8817..>9358
                     /locus_tag="ACHBV5_001905"
     CDS             8817..>9358
                     /locus_tag="ACHBV5_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4365 domain-containing protein"
                     /protein_id="HFM9967650.1"
                     /translation="MANNRKTETLGVSYLSTFIDKHELLQSYFESNDKTPVWDGEIHV
                     LKSPSEKKDEILGKVPVQIKTTRQKKDVLKSFSLDTRDLELYKPNGGVVLFVVWLNED
                     NGLRDIYYKSLPPLSIKNLLKKSKLKNKSTNRKKLSIEIFKLDEKKMYPMLVDFINNS
                     QKQYSFINVEGISVEDIPDD"
BASE COUNT         3021 a         1429 c         1888 g         3020 t
ORIGIN      
        1 ccatggttgg cgaaatatta tgccacgtcc agaacatcct aagaaagcag acgctcaaac
       61 cattgtcgcg tctaaaaata aaatctcaat tcaagaagaa aagaaagcgc tttaaaacca
      121 gtagaccttt tcataaggtt cgctcgatgt accaagatga ggctggtttc ggtagaatca
      181 gtaaactggg atcttgttgg tctccaatag gagtaggtcc acatgtccat agtcactata
      241 tacgagaatt tcgctattgt tatggagctg ttgatgccca tacaggcgaa tcatttttct
      301 taagagctgg tggatgtaat actgagtgga tgaacgcctt tttagaagag ctttcacaag
      361 cttatccaga tgattatctt ttactcgtta tggacaatgc tatatggcat aaatcaagta
      421 ccttaaagat tccgactaat attggctttg catttattcc tccgtacaca ccagagatga
      481 accccattga acaagtgtgg aaagagattc gtaaacgtgg atttaaaaat aaagcctttc
      541 aaactttgga agatgtcatg aatcaacttt aagatatcat acaaggactg gagaaggagg
      601 tgataaagcc catcgttaat cggagatgga ctagaatgct ttgtgaaagc agatgagtat
      661 aagtcctcgt tttgaaacct tagagcaggc cattgcctcc aaagatttgg aaaaagtccg
      721 agaagctttt aagaaaatga attccacttg gaccatcaat gaaagtgtgg ttcgtgacaa
      781 tagtacagct cattatggac gtgttgaaac agctatttcc ttcctgccta gtagcatgga
      841 aaccaaacct acagatgagt ctggaacatg aaaacagcag ttgatttcaa gaaacaaaaa
      901 agaacagccg aaactgttct cttatcatta tttgagaccg tattttttgt tgaaacgatc
      961 cacgcgtcca tctgcttgag tgaacttttg acgtccagtg tagaatgggt gtgagtctga
     1021 tgaaatttcc acacggatca atgggtaagt ttcgccttcg aactcaactg tttcgttaga
     1081 gcgttttgtt gaaccgctaa ggaattggta accagtagtt gtgtccatga agacaactgg
     1141 gcgatattct ggatggatat cttttttcat tttgcaatat ttcctttctg ccatggtctc
     1201 tttgcgagcc atagattgtt accatactag tctatcagat tctgaaaagt ttggcaagta
     1261 ttttatcagt ttttaagcaa gttttttaac ttttggtaga tgatttcgtt ttcttctagg
     1321 ctataggaat tagcaccact tgctagaggg tggcctccac catcatgctc cttggcgatt
     1381 tcattgatag gatggatttt actgcgtaag cgaactcggt agtggccatc agcctgttcg
     1441 acaaaaattc cccagagact cactctgtca atgcgtccag gtgcaccgac aatggctgca
     1501 gtttcagcat cggttacatt gtattgtttc aagacttctt gactcaggat aacgcgagca
     1561 gcaccatttt catccacttc cagatggtcg tagatgtagc cttgcagttt agcaattttg
     1621 tagctcatag tgtccatttt gcgagtgaga gccgcaaagt caaagttatg ttctctcaaa
     1681 taagcagcca ggcgaagagt ccgtgcagtg gtagaagggt agaggaagcg acctgtatca
     1741 ccgacaattc ctgcaaagag caactcagca tcgcgatctg ccaaggctag ttgggttgtt
     1801 tgggcaaata gggtaatcat ctcgctagcg ctacttgaac tagtatcgac ccaagacagg
     1861 tcaccgtata catcatcatt tggatggtgg tcaatcttaa tgagaaaatc accttgacta
     1921 tagcgcttat catcgatacg agcagtatta gctgtatcac agacgatgac aagtgcgcct
     1981 tggtaggctc tatcttcaac aagatccatc tcagccatcc aagtaagagt tggttcatca
     2041 aaaccgacgg ctttgatggt tttttctggg aaatgatgtt ccagcaaggc tttcaatccc
     2101 acctgacttc ccaaggcatc agggtctggt ttcatatgac gatgaatgat aatggtgtcg
     2161 tattctttaa ttttttctaa aatttgttgg caaatctcca taaataacct caattctttc
     2221 tcatttcatt gtagcacaag aatttttatt tttaaaatga aaaagatgtg atataatgga
     2281 gaaagataaa ttgaggagga cgatatggca ttagcaaaaa ttgtatttgc cagtatgacc
     2341 ggtaataccg aagaaattgc agatattgta gcagacaaat tacgtgactt gggcttggat
     2401 gttgatgttg atgaatgtac aactgttgac gcttcagact tcttggaagc agacatcgct
     2461 atcgttgcga cctatactta tggtgatggt gaattgccag atgagatgat ggacttctac
     2521 gaagacctag cagatctcaa cttgaatggc aaaatctacg gagtggtcgg ctcaggagat
     2581 accttctacg atgaattctg taaggctgtt gatgactttg accgtgtctt tgtgtcaata
     2641 ggagcagaaa aaggttcaga gtgtgttaaa gttgatcttt ctgccgagga agaagatatt
     2701 gaacgcttgg aacaattcgc agaagaattg gttgctaaag tagtataagc ataaaagtgc
     2761 gctgatgtaa tcaatcagtg catttttctt atcgagagtt gggattttac tagcctaatt
     2821 gatggctttt tgatacaata attcaaataa aggaggagac tgtatggatt tagatattat
     2881 tcgtcaagaa atcgatcaaa tcgatgacca aattgtcaaa ctgttagaag aacgaatgca
     2941 tttagttgag ggggtggttg cttataagaa agcttcaggt aaaccgattt tagatactaa
     3001 gagagaagaa gttatttttg aaaaggttag gagtcgtgta gaggacaagc gctatcagga
     3061 gactattgta gcgacttttt cggacatact caaacgttcg cgtgattatc aggatcaaaa
     3121 tatcaaatga aaaaagaaca attttatccg ctaggaattt ttctagctgc tatgttgggc
     3181 ggacttgtcc gatatctagt ttccacctgg ttaccagcca gtccagactt tccttggggc
     3241 actctctttg tcaactatct gggaattttc tgcttgattt ttcttgtcaa gggctatctg
     3301 gtctataagg ggactagtaa gggcttgatt ttagcactgg ggacgggttt ttgcggaggt
     3361 ttaacaactt tttccagcct aatgcttgat actgtgaagc tgcttgatac agggcgttat
     3421 cttagtttag tcctgtattt gcttttgagc atcggtggag gcctactctt agcttatttt
     3481 ctagggagga agaaatggta atcgtctatc ttgcaatcgc ctgtggcttg ggagcactcg
     3541 tacggtattt cttttcccgc tacaatcaag cttctaaatt gccactcgga acgctcatag
     3601 ctaatctttt aggttgtttt ttaattggag tattctacaa tcatgtagag tctaaggaag
     3661 tatatgctat tctagcaaca ggattttgtg gcggtttaac aactttttcg accttgaatg
     3721 acgaacttca aagactgtta agtgataaga aggtctttta ttcttacctg actttgactt
     3781 acataggtgg tttggttgcg atttttttag gaattttgct ataaatttct ttactttttt
     3841 gtgaaaattt ggtagactgt atcttgtgtg tgatggacgc acaaaaatac agtttatccg
     3901 ctgaggaaat ttcctcaaga ttgacaaaga taggagaata aaatgaatcc attaatccaa
     3961 agcttgactg aaggtcaact tcgtacagat atcccatcat tccgtcctgg tgacactgtt
     4021 cgtgtacacg cgaaagttgt cgaaggtaac cgtgaacgta tccagatttt tgaaggtgtt
     4081 gttatcgcac gtaaaggtgc tggaatctca gaaaactaca cagttcgtaa aatctctaac
     4141 ggtgtaggtg ttgagcgtat cttcccaatc cacactccac gtgttgaaaa aatcgaagtt
     4201 gttcgttacg gtaaagtacg tcgtgcgaaa ttgtactact tgcgtgctct tcaaggtaaa
     4261 gcagctcgta tcaaagaaat ccgtcgttaa ttcgactaaa aaactctgct tttcagcaga
     4321 gtttttatct agctccctta gttcaatgga tataacaact ccctcctaag gagtagttgc
     4381 aggttcgatt cctgcagggg gcatttttag taatgtaaag aaagacaaag aaaattcaaa
     4441 atgtttattt gaaggcaatt ttctcaagtt catttttaaa aataatttag catttttaat
     4501 ttttttgacc aaattttgac caaaaattat attttggtca atgattatag aataaaatgg
     4561 atcataaaaa tgtctttgat ttatagtagt gctaaaaagg acttccttta ttggaatgtc
     4621 cttattttta ttatggaatt gccaaatgac gttaaggttc agttctatga acttagaaag
     4681 aaagtacaaa gctttaatca gctttcaaaa agatttggta tggatgtttc tggctaaggt
     4741 atgtgacaag gtgaattgat cgttattgaa cagagagcgt taaaaaaggg aagaatcgtt
     4801 actattccac tgaattaaaa caagaaataa atcaacaaaa gcctatataa taacaaatgt
     4861 attaaaaata aaaagattta gttcagtgta atgcagaacc aaatcttatg gataaattat
     4921 ttgtctaatt ttttaggaat tatatctcta aacaatatca tttaacaatt aaattgttag
     4981 atctagctta aatttctggt ttaattcatt tattgtgtca ctatcattat attccttaaa
     5041 tattctcata gctttagaac attctttttt acctaactct atttgattag tttttataag
     5101 ataaatacct tttaggaaga gtaaataatt cttttcaaaa taatatcctt gcctagtaag
     5161 caaattttct aaatcatcta taaaaaattg agcactacct aataaattat tttttaataa
     5221 taattttagg ttaaataaat acaggggaat tattctatgc gttccagtat tagtttttaa
     5281 aaaatatcgt gtttttttga ttactattct atatagtaag ctaatggttc tagtattcat
     5341 aaaaaacact gaattataga aaagttttag ttcatactcc atccaagtat ctacagaaag
     5401 cagatatttt attaattcat tacatttaga tgaattataa ggaaggtttg caagacgatt
     5461 aatctgttgt tcagcaatca attttatgtg ataattgcat aaactttttt cttgcttttg
     5521 ttttaactct attttatcca ctaattcttg aagtaaaaat atatctgaag aatttacagc
     5581 atgttctaat tcttcaaaaa gacattcttt tttggaataa taacaatgaa ctaattcttc
     5641 aaattctgaa aatgatattc caagacggtt taacagaata taaaaatgat taatagataa
     5701 ttttgtaatg ccattttcga aacgagaaat agttgattca ctaatttcat tacatgataa
     5761 atctttaagg cgaaaatttt ttgaaatacg aatatccttt aaaactgctc cgaaattttc
     5821 cataatgttc ctcttccatt tctgcaaaaa ataaaacgct tgttttttat ttatgatatg
     5881 attatacaaa aataaaatag aaaggacaat aatatcatga aaaaaatttt attgtcaaca
     5941 gttgctttat taagcttagt agcatctctg ctagcaaata atccagtttc tgctcaagaa
     6001 tcatcctctc aagcaactta tagtaagtca agtggaagtt ggataaaatc tggtaaccgt
     6061 tggtggtata agcattctga tggttcttat actacaaatg gatgggaaaa aataaatggt
     6121 acctggtact attttgatag tgaaggttgg atgaagacag gttggattaa agaatatggg
     6181 aaatggtatt acctagatga tagtggtgct atgaaaactg gatggtgttt ggtttctggt
     6241 agctggtatt atttaaatag tagcggtgta atgcaaacgg gactacagac tatcaatgga
     6301 aaacaatatt atttagctgc cggcggtgct atgcagacag gttggcacaa tatcggagat
     6361 gatacctatt tctttgctaa tagtggggaa aatcaaaata tcaatcgtcg tgctttagtt
     6421 cttggtgaaa catcaacgag agcagtacct attgcagatg ttaatgctat ggaaaaggtt
     6481 tttaataacc aaaactttag tgaagttgtt cgtttcccag atagaacaaa atccgagata
     6541 attgcaaaaa tgcaagagct ttttgaatct tctagcgaag gcgatgtgaa ctatctttac
     6601 tttacttgtc atggaggaag agatggaaga atctatattg gtagtgatgg cctagcattt
     6661 tctggttggg aattggcgtc cgttttgaaa caatacaaag gtaagtttgt tgttatgctg
     6721 gattgttgtc atgctggaac aattatttct aaagataata caggtgaagg caatgaagga
     6781 gcctctacgg aatattttga tttagatgaa tttgtatcag gattttctaa tatggatggt
     6841 aacgaaaaat caggtgagat gattgactct aaatttttag tattatgctc atcaagaggt
     6901 gcagaatact ctagtggtgg atcattaagt ttagcgacta aatattggtc tttaggttca
     6961 ggatggaatc ctctacagaa ttcacaagca tatttagcag cagaccaaaa taataatcgc
     7021 agaatcacat taaatgaatt gtatacatac tctcgtgaac aagttttgaa acaaaattct
     7081 aaccagcata ttgaagttta tcctgacaac agtcaatttg tgttatttaa gaaataaggg
     7141 ggcaataaaa tgaaagtatc aaaaaaaatt acactattta gtttgtcttt tgcaggtttt
     7201 gttttattga ctttacctca agcaggaaag gcttttgaac ttaaagaaga ctgggcattt
     7261 aaaggtggca ttcgatacga gaatgggaaa gtcagcaaaa ttaataatgg atatgaagta
     7321 aatattaaag tgttagattt acctagtact agcgcaatcg aatggacagt tagattgaat
     7381 ggagaaaagc aaaatactaa cttcttagcg gaggaaagaa ctgtatctaa aactgaagat
     7441 aagggacgtt tcttgcactt ttatatcccc tatggatatc gtggggatat tgtagtagag
     7501 gctaagagtg gaaacgaagt gaagacttgg tctactaagg tagttgacga tgtttattca
     7561 gattctgcta agagtggcta ctttattctc gatggggaac aaatcttaga aagttcatgg
     7621 gattccgtaa atgagtctta tattgcaacg cttccaactg taacatcagg aaaaactgtt
     7681 gttgcttggc gtgaaaaagg aactcttaat ttaattaaac caggaagaat tgctcggcaa
     7741 tataatagca gtggatcata tgtagaactt tctccaatct ttgaaactgc tagttggcta
     7801 aaatcaaacc aaaactggta ctatcaaaaa caaggtcaat tagttcaaaa ttcttggatc
     7861 aaggatcagg gaagctggta ctttatggat gatgaagggg ttatgtttaa tcaaacatgg
     7921 ctacaccaag gtggaagctg gtatgccttt aagtcatcag gagccatgat ttcagctgat
     7981 tggttgtatg ataatggttc ttggtattac ctaaaggact caggttctat ggtaacagga
     8041 tggcttaaaa atggaggctc ttggtattac ctaaacaagt caggttcaat ggctacaggt
     8101 tggattaaag atagtggaac ttggtattat ctaaagaatt caggctctat ggcgacaggc
     8161 tgggtgaaag atagtggctc ttggtattat ctaaagaact caggttcaat ggcaacaggt
     8221 tgggtcaaag ataatggtaa gtggtactat ctcgcatcat ctggtaatat gcttcgcaat
     8281 acacgcacac cagatggcta ttatgtagat ggcagtggcg cttggaaata aatttttaaa
     8341 agagaaaatc tactgagaag gtagattttc tttttagtta atgaatatag aataaagtag
     8401 atcaggactg gtctatttta ttttgtaact attaatgaat agtcttaatg atgaagttac
     8461 tttctgaaga tatttaattg tgttgagatt tgataaaact atagcggatt gaaataagat
     8521 ataaacaaag agattatgga agtcaaatta atttctaaaa acgttttaaa atccttagcg
     8581 tactatttta gattcaattt aatatagttt aaaaataaga aaattacgta ccttattctt
     8641 ggtgataaaa atgtgaattt agataaatat atttgatttg tagaaggtgc tcataatcca
     8701 tattttaaaa tttatactat tatactgaaa tttaattgta gtttattgaa tgctatgtat
     8761 ttttatttct taatgctata atataaagta tatagagtta ttttagaggt gcagatttgg
     8821 ccaataatag gaaaactgag acattaggtg tttcatatct ttcaacattt atagataagc
     8881 atgagttact tcaatcttat tttgaaagta atgataaaac tccagtatgg gatggagaaa
     8941 ttcatgttct taaatcaccg agtgagaaga aagacgaaat attaggtaaa gtacctgttc
     9001 agattaaaac tactagacag aaaaaagatg tgttaaaatc cttctcatta gatactagag
     9061 atttagaact atataaacca aatggtggag tagttttatt tgtagtttgg ttgaatgagg
     9121 ataatggttt aagagatatt tactataagt cattacctcc tctttctata aagaatttgc
     9181 tcaaaaagag taaactaaaa aataaatcta caaataggaa gaaactttcc atagagattt
     9241 ttaaactgga tgagaaaaaa atgtatccaa tgttagtgga tttcataaac aatagtcaga
     9301 agcagtatag tttcataaat gtcgaaggta tttcagttga ggacattcct gatgataa
//
LOCUS       DAYYYC010000066         9246 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.066, whole genome shotgun sequence.
ACCESSION   DAYYYC010000066 DAYYYC010000000
VERSION     DAYYYC010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9246
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.066"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            67..312
                     /locus_tag="ACHBV5_001906"
     CDS             67..312
                     /locus_tag="ACHBV5_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967651.1"
                     /translation="MKAFYITIEKFIRDDESLKCYFIKVISSRSKVTSLDQIEADKTI
                     QRKYSSELKKFIGFYNEIICEENSFLHVRKRWSSWFR"
     gene            713..1705
                     /locus_tag="ACHBV5_001907"
     CDS             713..1705
                     /locus_tag="ACHBV5_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFM9967652.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1707..2525
                     /locus_tag="ACHBV5_001908"
     CDS             1707..2525
                     /locus_tag="ACHBV5_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9967653.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2527..3312
                     /locus_tag="ACHBV5_001909"
     CDS             2527..3312
                     /locus_tag="ACHBV5_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM9967654.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3351..3629
                     /locus_tag="ACHBV5_001910"
     CDS             3351..3629
                     /locus_tag="ACHBV5_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HFM9967655.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3614..3811
                     /locus_tag="ACHBV5_001911"
     CDS             3614..3811
                     /locus_tag="ACHBV5_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9967656.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(4087..4311)
                     /locus_tag="ACHBV5_001912"
     CDS             complement(4087..4311)
                     /locus_tag="ACHBV5_001912"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967657.1"
                     /translation="MKIKEQTRKLAADCSKQCFEVVDGTDVVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFEEIFEEYKSKTFVNRDTL"
     gene            4543..>9246
                     /locus_tag="ACHBV5_001913"
     CDS             4543..>9246
                     /locus_tag="ACHBV5_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HFM9967658.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKEENSNK
                     SQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGSKAIKELSSLKNTKVLYTYDRIF
                     NGGAIETTQDNLNKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHF
                     IRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKEKSSF
                     TIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAYEDES
                     ALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEIKATK
                     YDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDDRIKAETKIRMPEKNKETKAEY
                     PYVSSYGNVIELGEGD"
BASE COUNT         3147 a         1430 c         1868 g         2801 t
ORIGIN      
        1 attatggtat cgaatcttca tcagaatgat aaaattaatc aattgatatc tgattacaaa
       61 cagaatatga aagcttttta tatcactatt gaaaaattta tacgagatga tgaaagcctt
      121 aagtgttatt ttataaaggt tatttcaagt cgttccaagg taacaagtct agatcagatt
      181 gaagctgata aaacgataca aagaaaatat tcaagtgagc taaaaaaatt tattggattt
      241 tataatgaga ttatttgtga ggaaaatagt ttcctacatg tacgaaagag gtggtcgagt
      301 tggtttaggt agtcgatgcg tgagttgata attctcaggg tatggacttc tttttcatga
      361 atgaggtaaa agagcaggta ttgtttagag acaatcattc tgagcatatt ttctggatag
      421 agggagtatc cgattttatg atcaaagtta ataccgccct ctggtgagaa gatgagtagg
      481 ttggtaattt aaactattaa acagaatttt tgattaaaag tattatttta tgagagaaat
      541 cctaatttca caatccatag gcaaacgctt gcatttcgtt ttttattgga ctataatagg
      601 ttggtataaa gccttttgta gtaataaaat gtagaaggtg tagaaagcaa ggatttagaa
      661 tatttgtagt taaaaacaca atgttgctat tccttacgat agggagatag atatggcaat
      721 gatagaagtg gaacatcttc agaaaaattt tgtgaagact gttaaggaac cgggcttgaa
      781 gggggctttg cgctccttta ttcatcctga aaagcagacc tttgaagcgg tcaaggattt
      841 gacctttgag gttccaaaag ggcagatttt aggatttatc ggggcaaatg gtgctgggaa
      901 gtcgacaacc attaaaatgc tgacaggaat tttgaaacca acatctggtt tttgtcggat
      961 taacggcaag attccccagg acaatcggca agattatgtc aaagatattg gcgtagtctt
     1021 tggacaacgc acccagctat ggtgggattt ggctctgcaa gagacctaca ctgtcttaaa
     1081 agagatttat gatgtgccaa actcgctctt tcataagcgc atggactttt tgaatgaagt
     1141 cttggatttg aaggacttta tcaaggatcc cgtgcggact ctttcactgg gacaacggat
     1201 gcgggcggat attgcggcct ccttgctcca caatcccaag gttctttttt tagatgagcc
     1261 gaccattggt ttggacgttt cggttaagga taatattcgt cgggcaatta ctcagatcaa
     1321 tcaagaggaa gaaactacca ttcttttgac cactcacgat ttgagtgata ttgagcaact
     1381 ttgtgatcgg attttcatga ttgacaaggg gcaagagatt tttgatggaa cggtgagcca
     1441 actcaaggag acctttggta agatgaagac tctctctttt gaactgctac caggtcaaag
     1501 tcatctcgtc tctcactatg aaggtctgtc tgatatgacc attgatagac aaggaaacag
     1561 cctcaacatt gaatttgata gttctcgcta ccagtcagct gacattatca agcaaaccct
     1621 gtctgatttt gaaatccgcg atttgaagat ggtggatacg gatattgagg atattatccg
     1681 tcgcttctac cgaaaggagc tctaggatga tcaaattatg gagacgttat aaacccttta
     1741 tcaatgcagg ggttcaggag ttgattactt accgagtcaa ctttattctc tatcggattg
     1801 gcgatgtcat gggggctttt gtggcctttt atctctggaa ggctgtcttt gattcttcgc
     1861 aagagtcttt gattcagggc ttcagtatgg cggatatcac cctctacatc atcatgagtt
     1921 ttgtgaccaa tcttctgact agatccgatt cgtcctttat gattggggag gaggtcaagg
     1981 atggctccat tatcatgcgt ttgttgcgac cagtgcattt tgcggcctcc tatcttttca
     2041 ccgagcttgg ttccaagtgg ttgattttta tcagcgttgg ccttccattt ttaagtgtca
     2101 ttgtcttgat gaaaatcata tcgggtcaag gtattgtaga ggtgctagga ttaactgtca
     2161 tttatctttt tagcttaacg ctcgcctatc tgattaactt tttctttaat atttgctttg
     2221 gattttcagc ctttgtgttt aaaaatcttt ggggttccaa cctacttaag acttccatag
     2281 tggcttttat gtcggggagt ttgattccct tggcattttt tccaaaggtt gtttcagata
     2341 ttctctcctt tttgcctttt tcatccttga tttatactcc agttatgatc attgttggaa
     2401 aatacgatgc cagtcagatt cttcaggcac tccttttgca gttcttctgg ctcttagtga
     2461 tggtgggatt gtctcagtta atttggaaac gggtccagtc ctttatcacc attcaaggag
     2521 gttagtatga aaaaatatca acgaatgcat ctgattttta tcagacaata catcaaacaa
     2581 atcatggaat ataaggtaga ttttgtggtt ggtgtcttgg gagtctttct gactcaaggc
     2641 ttgaatctct tgtttctcaa tgtcatcttt caacatattc cattcctaga aggctggacc
     2701 tttcaagaga tagctttcat ttatggattt tccttgattc ccaagggaat ggaccatctc
     2761 ttttttgaca atctctgggc actagggcaa cgcctagtcc gaaaagggga gtttgacaag
     2821 tatctgactc gtcccatcaa tcctctcttt cacatcctag ttgaaacctt tcagattgat
     2881 gccttgggtg aactcttagt cggtggtatt ttattgggaa caacagtgac cagcattgtt
     2941 tggactcttc caaaattcct gcttttccta gtttgtattc cttttgcgac cttgatttat
     3001 acttctctta aaatcgcaac agccagtatc gccttttgga ctaagcagtc aggcgccatg
     3061 atttacatct tctatatgtt caatgacttt gctaagtatc cgatttctat ttacaattct
     3121 cttcttcgtt ggttgattag ctttatcgtg cctttcgcct ttacagccta ctatccagct
     3181 agctatttct tacaggaaaa ggatgtgttc tttaacgtag gaggtttgat gttgatttct
     3241 ctggttttct ttgttatttc ccttaaactt tgggataagg gcttagattc ctacgaaagt
     3301 gcgggttcgt aaaagctaaa gtaagactaa aatcaagaaa gaaacttatg atgtttgtaa
     3361 ttgaagaagt caaggatgaa aatcaaaaaa aggcagttgt cgctgaggtt ttgaaggatt
     3421 tgccagaatg gtttggaatc ccagaaagca cacaagccta tatagaagga accacgacac
     3481 tgcaagtttg gaccgcctat caggagagtg atttgactag atttgtaagc ttatcctatt
     3541 cgagtgaaga ttgtgcagag attgattgtc tcggcgtaaa aaagcttatc aaggtagaaa
     3601 aattgggagc caattgcttg ctactttaga gagtgaagct cgtaaaaaag ttggttatct
     3661 gcaggtcaaa acagtggcag aaggttctaa taaagattat gatcgaacaa atgactttta
     3721 tcgaggtctt ggctttaaaa agttagagat ttttcctcaa ctatggaatc cgcaaaatcc
     3781 ttgtcagatt ttgattaaaa agcttgaata atattacttg acatctattc tcagagtgct
     3841 atactgtaag tgtaatcgcc gatttagctt agttggtaga gcaaggcact cgtaaagcct
     3901 aggttatagg tagataaacg actgaggatt tgaaaaaata gataggtaga agataaccgt
     3961 taagccttac tcttagcggt tatttatatt gtttaatagc gctaatattt tatcaattat
     4021 gcctgttttc gtgtttctgg tagttgttca agtttattgc tactattttt gatggtatga
     4081 atgtgcttat aatgtatccc ggttaacgaa agttttggac ttatactctt cgaaaatctc
     4141 ttcaaaccac gtcaacgtcg ccttgccgtg cgtatggtta ctgacttcgt cagttctatc
     4201 cacaacctca aaacagtgtt ttgagctgac tacgtcagtt ccatctacaa cctcaaaaca
     4261 ctgttttgag caatctgcgg ctagtttcct agtttgctct ttgattttca ttgagtacta
     4321 atcttatttt ttaatgtgtg ctaaaaaata aattaactaa tgttaatttt tttgacttaa
     4381 atttttttaa atgatatact gtttttatag agagataaca attatatata aatgtactac
     4441 tctatttcct agataatact tagtaaaact ttttataaca aaggctagca aagttaaagt
     4501 ttattatcta ttggaagtta tataaatatg taaggaatta aaatgaaaaa aagtacagta
     4561 ttgtcattaa ccacagctgc agttatttta gcagcctatg cccctaatga ggtagtctta
     4621 gcagacacat ctagctctga agatgcttta agcatctctg ataaagaaaa agtagcagaa
     4681 aataaagaga aacataaaga tattcataat gctatagaaa cttcaaagga tactgaagaa
     4741 aagaaaacaa caattattga ggaaaaagaa gttgttagta aaaatcctgt gatagacact
     4801 aaaactagca atgaagaagc aaaaatcaaa gaagaaaatt ccaataaatc ccaaggagat
     4861 catacggact catttgtgaa taaaaacaca gaaaatccca aaaaagaaga taaagttgtc
     4921 tatattgctg aatttaaaga taaggaatct ggatcaaaag caatcaagga actatccagt
     4981 cttaagaata caaaagtttt atatacttat gatagaattt ttaacggtgg tgctattgaa
     5041 acaactcaag ataatctgaa taaaattaaa caaatagaag gtattacatc ggttgaaagg
     5101 gcacaaaaag tccaacccat gatgaatcat gccagaaagg aaattggagt tgaggaagct
     5161 attgattacc taaagtctat caatgctccg tttgggaaaa attttgatgg tagaggtatg
     5221 gtcatttcaa atatcgatac tggaacagat tataggcata aggctatgag aatcgatgat
     5281 gatgccaaag cctcaatgag atttaaaaaa gaagacttaa aaggaactga taaaaattat
     5341 tggttgagtg ataaaatccc tcatgcgttc aattattata atggtggcaa aatcactgta
     5401 gaaaaatatg atgatggaag ggattatttt gacccacatg ggatgcatat tgcagggatt
     5461 cttgctggaa atgatactga acaagatatc aaaaacttta acggcataga tggaattgca
     5521 cctaatgcac aaattttctc ttacaaaatg tattctgacg caggatctgg gtttgcgggt
     5581 gatgaaacaa tgtttcatgc tattgaagat tctatcaaac acaacgttga tgttgtttcg
     5641 gtatcatctg gttttacagg aacaggtctt gtaggtgaga aatattggca agctattagg
     5701 gcattaagaa aagcaggcat tccaatggtt gtcgctacgg gtaactatgc gacttctgct
     5761 tcaagttctt catgggattt agtagcaaat aatcatctga aaatgaccga cactggaaat
     5821 gtaacacgaa ctgcagcaca tgaagatgcg atagcggtcg cttctgctaa aaatcaaaca
     5881 gttgagtttg ataaagttaa cataggtgga gaaagtttta aatacagaaa tataggggcc
     5941 tttttcgata agaataaaat cacaacaaat gaagatggaa caaaagctcc tagtaaatta
     6001 aaatttgtat atataggcaa ggggcaagac caagatttga taggtttgga tcttaggggc
     6061 aaaattgcag taatggatag aatttataca aaggatttaa aaaatgcttt taaaaaagct
     6121 atggataagg gtgcacgcgc cattatggtt gtaaatactg taaattacta caatagagat
     6181 aattggacag agcttccagc tatgggatat gaagcggatg aaggtactaa aagtcaagtg
     6241 ttttcaattt caggagatga tggtgtaaag ctatggaaca tgattaatcc taataaaaaa
     6301 actgaagtca aaagaaataa taaagaagat tttaaagata aattggagca atactatcca
     6361 attgatatgg aaagttttaa ttccaacaaa ccgaatgtag gtgacgaaaa agagattgac
     6421 tttaagtttg cacctgacac agacaaagaa ctttataaag aagatatcat cgttccagca
     6481 ggatctacat cttgggggcc aagaatagat ttacttttaa aacccgatgt ttcagcacct
     6541 ggtaaaaata ttaaatccac gcttaatgtt attaatggca aatcaactta tggctatatg
     6601 tcaggaacta gtatggcgac tccaatcgtg gcagcttcta ctgttttgat tagacctaaa
     6661 ttaaaggaaa tgcttgaaag acctgtattg aaaaatctta agggagatga caaaatagat
     6721 cttacaagtc ttacaaaaat tgccctacaa aatactgcgc gacctatgat ggatgcaact
     6781 tcttggaaag aaaaaagtca atactttgca tcacctagac aacagggagc aggcctaatt
     6841 aatgtggcca atgctttgag aaatgaagtt gtagcaactt tcaaaaacac tgattctaaa
     6901 ggtttggtaa actcatatgg ttccatttct cttaaagaaa taaaaggtga taaaaaatac
     6961 tttacaatca agcttcacaa tacatcaaac agacctttga cttttaaagt ttcagcatca
     7021 gcgataacta cagattctct aactgacaga ttaaaacttg atgaaacata taaagatgaa
     7081 aaatctccag atggtaagca aattgttcca gaaattcacc cagaaaaagt caaaggagca
     7141 aatatcacat ttgagcatga tactttcact ataggcgcaa attctagctt tgatttgaat
     7201 gcggttataa atgttggaga ggccaaaaac aaaaataaat ttgtagaatc atttattcat
     7261 tttgagtcag tggaagaaat ggaagctcta aactccaacg ggaagaaaat aaacttccaa
     7321 ccttctttgt cgatgcctct aatgggattt gctgggaatt ggaaccacga accaatcctt
     7381 gataaatggg cttgggaaga agggtcaaga tcaaaaacac tgggaggtta tgatgatgat
     7441 ggtaaaccga aaattccagg aaccttaaat aagggaattg gtggagaaca tggtatagat
     7501 aaatttaatc cagcaggagt tatacaaaat agaaaagata aaaatacaac atccctggat
     7561 caaaatccag aattatttgc tttcaataac caagggatca acgctccatc atcaagtggt
     7621 tctaagattg ctaacattta tcctttagat tcaaatggaa atcctcaaga tgctcaactt
     7681 gaaagaggat taacaccttc tccacttgta ttaagaagtg cagaagaagg attgatttca
     7741 atagtaaata caaataaaga gggagaaaat caaagagact taaaagtcat ttcgagagaa
     7801 cactttatta gaggaatttt aaattctaaa agcaatgatg caaagggaat caaatcatct
     7861 aaactaaaag tttggggtga cttgaagtgg gatggactca tctataatcc tagaggtaga
     7921 gaagaaaatg caccagaaag taaggataat caagatcctg ctactaagat aagaggtcaa
     7981 tttgaaccga ttgcagaagg tcaatatttc tataaattta aatatagatt aactaaagat
     8041 tacccatggc aggtttccta tattcctgta aaaattgata acaccgcccc taagattgtt
     8101 tcggttgatt tttcaaatcc tgaaaaaatt aagttgatta caaaggatac ttatcataag
     8161 gtaaaagatc agtataagaa tgaaacgcta tttgcgagag atcaaaaaga acatcctgaa
     8221 aaatttgacg agattgcgaa cgaagtttgg tatgctggcg ccgctcttgt taatgaagat
     8281 ggagaggttg aaaaaaatct tgaagtaact tacgcaggtg agggtcaagg aagaaataga
     8341 aaacttgaca aagacggaaa taccatttat gaaattaaag gtgcgggaga tttaagggga
     8401 aaaatcattg aagtcattgc attagatggt tctagcaatt tcacaaagat tcatagaatt
     8461 aaatttgcta atcaggctga tgaaaagggg atgatttcct attatctagt agatcctgat
     8521 caagattcat ctaaatatca aaagcttggc gagattgcag aatctaaatt taaaaattta
     8581 ggaaatggaa aagagggtag tctaaaaaaa gatacaactg gggtagaaca tcatcatcaa
     8641 gaaaatgaag agtctattaa agaaaaatct agttttacta ttgatagaaa tatttcaaca
     8701 attagagact ttgaaaataa agacctaaag aaactcatta aaaagaaata taaggaagaa
     8761 gacgactttg taactggtgg aaaaagaaca gtagaacttg attataaata tgacgataaa
     8821 ggaaatataa ctgcctatga agatgaaagt gctctagaat atgaaactga aaaatttgac
     8881 gaaataaaat caaaaattta tggtgttcta agcccatcta aagatggaca ctttgaaatt
     8941 cttggaaaga taagcaatgt ttctaaaaat gccaaggtat attatggaaa taactataaa
     9001 tttatagaaa tcaaagcgac taagtatgac tcacattcaa aaacgatgac atttgattta
     9061 tacgctaata ttaatgatat tgtggatgga ttagcttttg ctggagatat gcggtttttt
     9121 gttaaagatg atgatcgaat aaaagctgaa actaaaatta gaatgcctga aaaaaataag
     9181 gaaactaaag cagaatatcc ctatgtatca agttatggga atgtaatcga attaggagaa
     9241 ggagat
//
LOCUS       DAYYYC010000067         9134 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.067, whole genome shotgun sequence.
ACCESSION   DAYYYC010000067 DAYYYC010000000
VERSION     DAYYYC010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.067"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(293..1054)
                     /locus_tag="ACHBV5_001914"
     CDS             complement(293..1054)
                     /locus_tag="ACHBV5_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFM9967659.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(1342..2304)
                     /gene="nrdF"
                     /locus_tag="ACHBV5_001915"
     CDS             complement(1342..2304)
                     /gene="nrdF"
                     /locus_tag="ACHBV5_001915"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFM9967660.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(2492..4651)
                     /gene="nrdE"
                     /locus_tag="ACHBV5_001916"
     CDS             complement(2492..4651)
                     /gene="nrdE"
                     /locus_tag="ACHBV5_001916"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFM9967661.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWTELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(4732..4950)
                     /gene="nrdH"
                     /locus_tag="ACHBV5_001917"
     CDS             complement(4732..4950)
                     /gene="nrdH"
                     /locus_tag="ACHBV5_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFM9967662.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPEKLKQLA"
     gene            5301..5564
                     /locus_tag="ACHBV5_001918"
     CDS             5301..5564
                     /locus_tag="ACHBV5_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFM9967663.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            5570..7303
                     /gene="ptsP"
                     /locus_tag="ACHBV5_001919"
     CDS             5570..7303
                     /gene="ptsP"
                     /locus_tag="ACHBV5_001919"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFM9967664.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            7558..>9134
                     /locus_tag="ACHBV5_001920"
     CDS             7558..>9134
                     /locus_tag="ACHBV5_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HFM9967665.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKL
                     VDDILAFLAPIRHPERLG"
BASE COUNT         2841 a         1703 c         1886 g         2704 t
ORIGIN      
        1 ttcaacaatc gtaaccaatt tctcaaaaaa gttaaatctt atatttagta ctctgtaaaa
       61 ctcttatcta atcacgttgc ttatactcaa tgaaaatcaa agagcaactt taaactagga
      121 agcgagtcgc agatttctca atgcatagct ttgaggaatt gggcaaaaag tctttgatat
      181 agaaaaaagc atagtatcag gtgttgaaac acctgatact atgcttttta ttgtgggaag
      241 atttactttt tttcttctga aattgagttg ttacccaggc tctttcagtt tattaaggct
      301 tgatgacttt aatgtgttta gatagcttaa aaaggattga atcacttagt ttagaatctg
      361 aaacaatagt atcaagattt gatatattat aaaaagtata aaaatcaaac ttattgaact
      421 tactatgatc tgcgagtaaa tattttttat tagaattatt taaagcgatg cgttgagcct
      481 ctccctcttc ctcgctaaaa gtagctagag ctccgttttg aataccatta cagctaacga
      541 aagctttaga aaattggaga ttagagagat tttgtagggt caatgtgcca acaaaagcac
      601 ctgtaatatc gcgataattt ccacctatca aaatcaaatc tgttaatttt cgttcgctta
      661 aaatcagaaa aacaggtaga ctgttggtta cgacgcggat attgtcaata ggcaactcac
      721 gcgcaaaaaa ctctaatgtt gttcctggtc caatgaaaat agtttctctt tcttctacta
      781 gactgcctgc aaaatgggct atttcttgtt tttctgccgt ttggagggct tgtttttcaa
      841 tatttgatcg ctcattagtc aaaagggagt tggttcgaag tttttcagct ccaccatgca
      901 cacgaatcag caaatcttta tcagctaatt cctgtaaata gcgccttgca gtcatatctg
      961 aaacggctat ttcgtccata atctgtttaa ctgttatggt tcctttacta tttactatct
     1021 ctaaaatttt ggttaatttt tcttgtttga gcatattatc acctcgtttc ctactactat
     1081 cttaccataa acaaactcat cattcaaata caaaaacaac aaaatgaaac aaaaacaaaa
     1141 atatcgaagt ttgttttcaa aactttcgat atttttgttg ggttattatt ttgttgtttc
     1201 tagtttactt tttgatggtt aagagtggtg gagaattata ctcaatgaaa atcaaagagc
     1261 aaactaggaa gctagccgca ggctgtactt gagtacggca aggcgaagct gacgtggttt
     1321 gaatttgatt ttcgaagagt attagtccaa accgtagttg tagtcatcat cttgcatggc
     1381 ttcaacttcg ccaagaaggt aaccatttcc gacttgagag aagaagtcat ggttggaagt
     1441 tcctgttgaa ataccgttca taacgattgg gttgacatct tcagctgaat ctgggaaaag
     1501 tggatcttgt cccatgttca tgagagcttt attggcattg tagcgaagga aggttttaac
     1561 ctcttcagtc caaccaacac cgtcataaag actctctgtg tagccttctt cattttcata
     1621 aagagtatag agtaggtcgt acatccattc tttgagtttt tcttgctctt cttcaggtaa
     1681 ttcattgaaa ccaagttgga atttgtaacc aatgtaggtt ccgtgaacag actcgtcacg
     1741 aataatcaat ttaatgattt ctgcaacgtt ggcaagtttg ttgttaccga gatagtagag
     1801 gggagtgaag aaaccagagt agaagaggaa ggtttcgagg aagacgctgg caactttctt
     1861 ttcaagtggg ctgccgttta ggtagatttc gttgacaatc tcagccttct tttgtaggta
     1921 aggattggta ttggtccatt cgaaaatttc ttcaatctca gccttagtat tcaaggtaga
     1981 aaagattgat gagtaagatt tagcgtggac agattccata aattggatgt tattgaaaac
     2041 agcttcctca tgtggtgtac ggatgtctgc gcgaagggct tgaaccccag tttcagattg
     2101 catagtgtca agaagggtta aaccaccaaa aacttttccg accaagtctt tctctttgtt
     2161 agatagcttt ctccagtcat ccaagtcgtt tgataaggga atacgtgtat cgagccaaaa
     2221 ttgctccgtc agtttttccc aagttgattt gtcgatgaca tcttcgatgg cattccagtt
     2281 aatggctttg tagtaagttt ccatttaaaa tctctttctg tgtttagtat tgcgaactca
     2341 caattatttc tactttacca taattctata ggagtatcgc acaaaaagtc ggaagcccga
     2401 cttttaaaat gttacataaa ttatgttatg acatagtaga tttgatttta tcagtgctgc
     2461 ttagggaaaa atagtgtttc tatgctagaa actaaatcac acagctttca cattggttgg
     2521 cgccgacttc tccaccgtca tctgtaaagg tacggacgta gtagatagac ttgattccct
     2581 tgttaaaggc atagttacga aggatggaca agtcacgtgt cgtttgttta ttttccctct
     2641 tccattcgta aaggcctttt ggaatgtcac tacgcatgaa gagggtgagt gaaagtcctt
     2701 gatccacgtg ttcagtcgca gcagcgtaaa catcgatgac tttacgcata tccatatcgt
     2761 aggcagaagt gtagtaagga atggtttctg tagacaagcc agcagcaggg tagtagattt
     2821 taccaatttt cttttcctga cgttcttcaa tacgttgcgt aatcgggtgg atagaagcag
     2881 aaacatcgtt gatgtagctg atagaaccat ttggcgctac agcaaggcga ttttggtggt
     2941 aaagaccatc ctcttgaacc ttgtcgcgaa gttcagtcca atcagcaaca ccagggataa
     3001 aaacattttt gaagagttct ttaacacggt ctgatgttgg aacaaattca ccagttacat
     3061 acttgtcaaa gtaacttccg ttagcatagt ctgatttttc aaagttgtgg aaggtaatac
     3121 cacgttcacg cgcaatattg tttgactcta ccaaggtcca gtagttcata agcataaagt
     3181 agatgcttgt aaattcaaca gactcaggtg aaccatattc aatgagttgt tgggcaaggt
     3241 agctgtgcag tcccatggca ccgagaccaa aggtgtgggc ttggctattt ccatggtcaa
     3301 tcgttggtac agctacgata tgtgaactat ctgtaacgaa agtaagggca cgaaccatag
     3361 cacggataga acgaccaaaa tcaggtgaag tcatcatgtt aaccacgttg gttgaaccca
     3421 ggttacatga aacatctgtt cccatttgaa ggaattcttg agcatcgttg atcaagcttg
     3481 gttcttgaac ttgaagaatc tcagaacaca agttactcat gataatcttt ccatcgacag
     3541 gatttgcacg gttagccgta tctatgttga ctacataagg atagccagac tcttgttgca
     3601 atttagagat ttcagtttcc aaatcccgcg ccttgatttt tgtcttgcga atatttggat
     3661 ttgcgaccaa ttcatcgtat ttttcagtaa tgtcgatgta attgaatggc acaccgtatt
     3721 ctttttctac agagtaaggg ctgaagaggt acatttcttc atttttacga gccaattcgt
     3781 agaatttatc aggtactaca acaccaagtg atagagtctt gacacgtact ttttcatcag
     3841 cgttttcttt cttagttgaa aggaaagcga tgatatctgg gtgaaagacg ttgaggtaga
     3901 caacaccggc accttgacgt tgccccaatt ggttggagta agagaagctg tcttcaaaaa
     3961 gcttcataac aggaacgaca cctgaagcag ctccttcata gcctttgata ggtgcaccag
     4021 cttcacgaag gttgctgagg gtaattccca caccaccacc aatacgtgaa agttgaagag
     4081 ctgagttgat agaacgtccg atagagttca tatcatccgt cacttggatt aggaaacaag
     4141 ataccaactc cccacgacga gcacgtccag cattcaagaa ggaaggagta gcaggttggt
     4201 agcgttggtg gatgatttca ttggcaatat cgattgcaac agcttcattc ccatcagcga
     4261 aataaagggc gttgaagaag acacggtctt ccatattttc aagatagtat tcaccgtcat
     4321 tagtctttaa ggcatattga ttgtaaaatt tataagctgc catgaatgac ttgaattgga
     4381 agttttggtc tttgataaat tgagccaatt cttccaagaa ctctggacgg tatttcttga
     4441 taaaggctgt ttcgatgtag ttgtgttcaa tgaggtaatt gattttgtct ttgattgaat
     4501 caaaaaccat agtgtttgga actacatttt ctttaaagaa agcatccaag gcttccttat
     4561 ctttatgaag catgatttgt ccattaacag gacggttaat ttcgttatta agacggaagt
     4621 aagtcacgtc ttcaagatgt tttaatccca taaaatttcc cttatctaat tacaaaagaa
     4681 aggcttctaa gttagcccta aaagcagttt cttctggatg atgtactaag attatgctaa
     4741 ttgtttcagt ttttctggtt ggaaacctga aaagacttca gttggtgttt ggataacagg
     4801 agctgcgcta aaaccgagct ctttaacttg atcgacgtac tcaggttgct catcaagatt
     4861 gatttcacga taagagacat tattactgtc caagaaacgc ttggtcattt tacattggac
     4921 acaattgttt ttagaataaa cggttaccat tgtgtaactc ctcttcaaaa tttaatacta
     4981 tcttagtata tcagaaaata aaattttgtc aatgatttaa actaaatata gtggtgttct
     5041 tttgttgttt ttatatataa acacaatata tagtgtttgt attgtgaaat agcaatgatt
     5101 atcctataaa ttgtttttga agaaactata tcctgtgttt tgttatctag gatagaagat
     5161 tttcagcaag ttatctgaaa ggaaattgaa ggaaaatcca gaaaatgctt gaaaaaaatc
     5221 ctagaagatg gtataatact aaattgtaag ggttatcaca tataactcaa aaaaagaaag
     5281 aacaaaagga gagtcaaact atggcttcta aagatttcca cgtagtggca gaaacaggta
     5341 ttcacgcacg tccagcaaca ttgttggtac aaactgctag caaatttgct tcagatatca
     5401 ctcttgagta caaaggtaaa tcagttaacc ttaaatcaat tatgggtgtt atgagtcttg
     5461 gtgttggtca aggtgctgac gtaactatct cagctgaagg tgcagatgca gatgacgcta
     5521 tcgctgcaat ctcagaaaca atggaaaaag aaggattggc ataagggaaa tgacagaaat
     5581 gcttaaagga atcgcagcat ctgacggtgt tgcagttgca aaagcatatc tactcgttca
     5641 gccggatttg tcatttgaga ctattacagt cgaagataca aacgcagaag aagctcgcct
     5701 tgatgccgct ctacaggcat cacaagacga gctttctgtt attcgcgaga aagcagtagg
     5761 tacgctcggt gaagaagcag ctcaagtttt tgatgctcac ttaatggttc ttgctgaccc
     5821 agaaatgatc agccaaatca aggaaactat ccgtgcgaag aaagtgaatg cagaagcagg
     5881 tctgaaagaa gttacagata tgtttatcac tatctttgaa ggcatggaag acaacccata
     5941 catgcaagaa cgcgcagcgg atatccgcga cgtgacaaaa cgtgtattgg caaaccttct
     6001 tggtaaaaaa ttgccaaacc cagcttctat caatgaagaa gtgattgtga ttgcgcatga
     6061 cttgactcct tcagatacag ctcaattgga caaaaacttt gtaaaagctt ttgtaaccaa
     6121 cattggtgga cgtacaagcc actcagctat catggcacgt acacttgaaa ttgctgctgt
     6181 attaggtaca aacaacatca ctgaaatcgt taaagacggt gacatccttg ctgttaacgg
     6241 gatcactgga gaagtgatta tcaacccgac agatgaacaa gcggcagaat ttaaagcagc
     6301 tggtgaagcc tatgcgaaac aaaaagctga atgggcactt ttgaaagatg ctcaaacagt
     6361 gactgctgac ggtaaacact tcgagttggc tgccaatatt ggtactccaa aagacgttga
     6421 aggtgttaac aacaacggtg cagaagctgt tggactttac cgtacagagt tcttgtacat
     6481 ggattctcaa gacttcccaa ctgaagatga gcagtatgaa gcatacaagg ctgttcttga
     6541 aggaatgaac ggtaaacctg ttgtcgttcg tacaatggat atcggtggag ataaggaact
     6601 tccttacttc gatatgcctc acgaaatgaa cccattcctt ggattccgtg ctcttcgtat
     6661 ctctatctct gagactggag atgctatgtt ccgcacacaa atccgtgctc ttcttcgtgc
     6721 gtctgttcac ggtcaattgc gtatcatgtt cccaatggtt gcgctcttga aagaattccg
     6781 tgcagcgaaa gcagtctttg atgaagaaaa agcaaacctt cttgctgaag gtgttgcagt
     6841 tgcggataac atccaagttg gtatcatgat cgagattcct gcagcggcta tgcttgcaga
     6901 ccaatttgct aaagaagttg acttcttctc aattggtaca aacgacttga tccaatatac
     6961 aatggcagca gaccgtatga acgaacaagt ttcatacctt taccaaccat acaacccatc
     7021 aatcctacgc ttgattaaca atgtgatcaa agcagctcac gctgaaggta aatgggctgg
     7081 tatgtgtggt gagatggctg gtgaccaaca agctgttcca cttcttgtcg gaatgggctt
     7141 ggatgagttc tctatgtcag caacatctgt acttcgtaca cgcagcttga tgaagaaact
     7201 cgacacagct aagatggaag agtacgcaaa ccgtgccctt acagaatgct caacaatgga
     7261 agaagttctt gaacttcaaa aagaatacgt taattttgat taatcgaaaa gtccctgcaa
     7321 ctcagttaca gggacttttt ttgatatttt aaaaagaatt ttcaagaaaa tctttcttat
     7381 aaaaagtcca accttgaaaa agtagtggtc agaacaaaaa atacttaaat ggttcataaa
     7441 attcttgaca agttggagat ttaggagtaa actattaacc agttaagtaa tagagaggag
     7501 tttctgcaat ttagaaatga attgcaacta gaaatatcaa atagaaagag agtttcgatg
     7561 aaaattaata agaaatacct tgttggttct gcggcagctt tgattttaag tgtttgttct
     7621 tacgagttgg gactgtatca agctagaacg gttaaggaaa ataatcgtgt ttcctatata
     7681 gatggaaaac aagcgacgca aaaaacggag aatttgactc ctgatgaggt tagcaagcgt
     7741 gaaggaatca atgctgagca aatcgtcatc aagataacag accaaggcta tgtcacttca
     7801 catggcgacc actatcatta ttacaatggt aaggttcctt atgatgcgat tttcagtgaa
     7861 gaattactca tgaaagatcc aaactataag ctaaaagatg aggatattgt taatgaggtc
     7921 aagggtggat atgttatcaa ggtagatgga aaatactatg tttaccttaa ggatgctgcc
     7981 cacgcggata acgtccgtac aaaagaggaa atcaatcgac aaaaacaaga acatagtcaa
     8041 catcgtgaag gtgggactcc aagaaacgat ggtgctgttg ccttggcacg ttcgcaagga
     8101 cgctatacta cagatgatgg ttatatcttt aatgcttctg atatcataga ggatactggt
     8161 gatgcttata tcgttcctca tggagatcat taccattaca ttcctaagaa tgagttatca
     8221 gctagcgagt tagctgctgc agaagccttc ctatctggtc ggggaaatct gtcaaattca
     8281 agaacctatc gccgacaaaa tagcgataac acttcaagaa caaactggct accttctgta
     8341 agcaatccag gaactacaaa tactaacaca agcaacaaca gcaacactaa cagtcaagca
     8401 agtcaaagta atgacattga tagtctcttg aaacagctct acaaactgcc tttgagtcaa
     8461 cgccatgtag aatctgatgg ccttgttttc gacccagcgc aaatcacaag tcgaaccgcc
     8521 agaggtgtag ctgtccctca tggtaaccat taccacttta tcccttatga acaaatgtct
     8581 gaattggaaa aacgaattgc tcgtattatt ccccttcgtt atcgttcaaa ccattgggta
     8641 ccagattcaa gaccagaaca accaagtcca caatcgactc cggaacctag tccaagtctg
     8701 caacctgcac caaatcctca accagctcca agcaatccaa ttgatgagaa attggtcaaa
     8761 gaagctgttc gaaaagtagg cgatggttat gtctttgagg agaatggagt ttctcgttat
     8821 atcccagcca aggatctttc agcagaaaca gcagcaggca ttgatagcaa actggccaag
     8881 caggaaagtt tatcgcataa gctaggagct aagaaaactg acctcccatc tagtgataga
     8941 gaattttaca ataagactta tgacttacta gcaagaattc accaagattt acttgataat
     9001 aaaggtcgac aagttgattt tgaggctttg gataacctgt tggaacgact caaggatgtc
     9061 tcaagtgata aagtcaagtt agtggatgat attcttgcct tcttagctcc gattcgtcat
     9121 ccagaacgtt tagg
//
LOCUS       DAYYYC010000068         9004 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.068, whole genome shotgun sequence.
ACCESSION   DAYYYC010000068 DAYYYC010000000
VERSION     DAYYYC010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9004
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.068"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            1..535
                     /locus_tag="ACHBV5_001921"
                     /pseudo
     CDS             1..535
                     /locus_tag="ACHBV5_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            551..1048
                     /locus_tag="ACHBV5_001922"
                     /pseudo
     CDS             551..1048
                     /locus_tag="ACHBV5_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
     gene            1205..1630
                     /gene="lacA"
                     /locus_tag="ACHBV5_001923"
     CDS             1205..1630
                     /gene="lacA"
                     /locus_tag="ACHBV5_001923"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HFM9967666.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1661..2176
                     /gene="lacB"
                     /locus_tag="ACHBV5_001924"
     CDS             1661..2176
                     /gene="lacB"
                     /locus_tag="ACHBV5_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HFM9967667.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            2187..3116
                     /locus_tag="ACHBV5_001925"
     CDS             2187..3116
                     /locus_tag="ACHBV5_001925"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HFM9967668.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            3118..4098
                     /gene="lacD"
                     /locus_tag="ACHBV5_001926"
     CDS             3118..4098
                     /gene="lacD"
                     /locus_tag="ACHBV5_001926"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFM9967669.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGETAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            4332..5168
                     /locus_tag="ACHBV5_001927"
     CDS             4332..5168
                     /locus_tag="ACHBV5_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFM9967670.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYCQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            5204..5521
                     /locus_tag="ACHBV5_001928"
     CDS             5204..5521
                     /locus_tag="ACHBV5_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFM9967671.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5523..7217
                     /locus_tag="ACHBV5_001929"
     CDS             5523..7217
                     /locus_tag="ACHBV5_001929"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HFM9967672.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            7426..8832
                     /gene="lacG"
                     /locus_tag="ACHBV5_001930"
     CDS             7426..8832
                     /gene="lacG"
                     /locus_tag="ACHBV5_001930"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFM9967673.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTDYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8875..9004
                     /locus_tag="ACHBV5_001931"
                     /pseudo
     CDS             8875..9004
                     /locus_tag="ACHBV5_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
BASE COUNT         2905 a         1534 c         1865 g         2700 t
ORIGIN      
        1 aagtaactct tgttcaaagt ggtgttacgg tttcaagaac tcctctcagc tctgaggaca
       61 cggtaatgat tgatgcgacg gaagtacaaa tcaatcgccc taaaaaagaa ttagcgaatg
      121 attctggtaa aaagaaatgc cacgctatga aggctcaagc gattgtcaca agtcaaggga
      181 gattgtttct ttggatatca ctgtgaacta ttgtcatgat atgaagttgt tcaaaatgag
      241 tcgcagaaat atcggacaag ctggtaaaat cttggctgac agtggttatc aagggctcat
      301 gaagatatat cctcaagtac aaactccacg taaatccagc aaactcaagc cgctaacagt
      361 tgaagataaa acctataacc atgcgctatc taaggagaga agcaaggttg agaacatctt
      421 tgccaaagta aaaacgttta aaatgatttc aacaacctat cgaaatcatc gtaaacgctt
      481 cggattacga atgaatttga ttgctggcat tatcaatcat gaactaggat tctagttttg
      541 caggaagtct aataaagaaa ctagcaaggt caggccttac tttattggtg gacatccagg
      601 atttaattgt cctctacttg atgatgaagt ctatgaagat tattatctag agtttgagaa
      661 agaagagact tgctctgttc cacgtccttt cccagaaaca ggtatgttgg atttccaaga
      721 tagaagtcca tggctagagg gacaaaaaga aatagatctt agttatgatc ttttcagcaa
      781 agatgcagtg actttggatg aattgcaatc tcgaacaatt gcccttcgtt ctcttaaaca
      841 tgatagggga ttgaaagtgc attttgcaga atttccaaac ctcatcatct ggtcaacttt
      901 gaacaaggga cctttcatta cctttgaacc atggtctggc ttgtcaacat tccttgaaga
      961 aggagatcat ttagaagata agaagaatgt ttgtctctta gaagccaatc aggttgaaga
     1021 attagggttt gagatagaag ttttataaaa aagtaaaaaa taaataacaa aaacaaacac
     1081 aaactgttga cttcttcaaa caatagtagt atattatgtt tgtgaggact aattgactgt
     1141 tttttaaaga cagccaatac actgctggaa tccagcatag aaaaaataaa aaggagtata
     1201 caatatgtct attgttatcg gtgcagatgc tgcaggtttg agattgaaag aagttgtgaa
     1261 agacttctta gaaaaagaaa acttccacct tgtggatgtt acagctgaag gtcaagactt
     1321 tgttgatgtg actctcgctg ttgctgcaga agtaaacaaa gaagaacaaa accttggtat
     1381 cgtgattgat gcttatggag ctggtccatt tatggttgca actaagatca aaggaatggt
     1441 tgctgcagaa gtttctgatg aacgttcagc ttatatgact cgtggccaca acaactcacg
     1501 tatgatcact atgggtgcac aacttgttgg tgatgaattg gctaaaaaca tcgctaaagg
     1561 atttgttaat ggtaaatacg acggtggtcg tcaccaaatc cgggttgaca tgttgaacaa
     1621 aatgggctaa ttagattata gtaagaaagg taagttaaaa atgagaattg caattggatg
     1681 tgaccacatc gtaacagatg aaaaaatggc ggtttcagaa tttttgaaat caaaaggata
     1741 tgaagtcatt gactttggta catatgacca tacacgtact cactacccaa tctttggtaa
     1801 aaaagtaggg gaagctgtaa ctagcggtca agctgatctt ggagtatgta tctgtggtac
     1861 tggtgttggt atcaacaacg ctgtaaataa agttccaggt gttcgttctg ccttggttcg
     1921 tgatatgaca acagcccttt atgctaaaga acaattgaac gctaacgtta ttggttttgg
     1981 tggtaaaatt actggtgaat tgcttatgtg tgatatcatc gaagctttca tccatgctga
     2041 atacaaacca actgaagaaa acaaaaaatt gattgcgaaa attgaacatg ttgaaagtca
     2101 caatgctcaa caaacagacg caaacttctt cactgaattc cttgaaaaat gggatcgcgg
     2161 agaataccac gactaagagg taacctatga ttttaacagt tacaatgaac ccatccattg
     2221 atatttccta tcccttggat gagttgaaga ttgatactgt caatcgtgtg gtggatgtaa
     2281 ccaaaacggc tggtggtaag ggactcaatg ttacccgagt actttcagaa tttggcgatt
     2341 ctgttcttgc tactggttta gtgggtggca aacttggtga gtttttggtt gaacatatcg
     2401 ataatcaagt aaagaaagat ttcttctcaa ttcagggaga aactcgtaac tgtatcgcta
     2461 ttctccacgg agacaaccaa acagaagttc ttgaaaaagg tcctgaagta ttggaacagg
     2521 aaggtcaaga ctttttggaa catttcaaaa aactcttgga gtcagttgaa gtagtggcca
     2581 tctcaggtag tctgccagct ggccttccag ttgattacta tgcgagcttg gtagaacttg
     2641 ctaatcaagc tggcaagcct gtagtcttgg actgctcagg tgcagcactt caggctgttc
     2701 ttgaatcacc ccataaacca acagtcatca aaccaaataa tgaagaattg tctcagcttc
     2761 ttggaagaga agtttctgag gatttggatg aattaaaaga agtacttcaa gaacctttgt
     2821 ttgcagggat tgaatggatt atcgtttcac ttggtgccaa cggtactttt gccaaacatg
     2881 gtgacacttt ctacaaggta gatattccta gaattcaggt ggtaaatcct gttggatctg
     2941 gagactctac tgtggcagga atttcttcag gacttcttca caaagaatcg gatgcagaat
     3001 tactcatcaa ggcaaatgtc cttggtatgc tcaatgctca agaaaaaatg actggtcatg
     3061 tcaacatggc caactatcaa gttctatatg atcaattaat agtaaaagag gtataaaatg
     3121 gctttaacag aacaaaaacg tgtacgctta gaaaaacttt ctgatgaaaa tggtatcatc
     3181 tcagctcttg catttgacca acgtggtgct ttgaaacgcc tcatggctca acaccaaaca
     3241 gaagaaccaa ctgtggccca aatggaagaa cttaaagtct tggtagcaga tgaattgact
     3301 aaatacgctt catctatgct tcttgaccct gagtatggac ttccagcaac taaagctctt
     3361 gatgaaaaag ctggtcttct ccttgcttat gaaaaaacag gttatgacac aacaagcaca
     3421 aaacgcttgc cagactgctt ggatgtctgg tctgcaaaac gtattaaaga agaaggtgca
     3481 gatgcagtta aattcttgct ttactatgat gtagatagct cagacgaact caatcaagaa
     3541 aaacaagcct acatcgaacg catcggttct gagtgtgtgg ctgaagatat cccattcttc
     3601 cttgaaattc ttgcttacga tgaaaaaatt gcggatgcag gttctgtaga atacgcgaaa
     3661 gtaaaaccac acaaagttat cggcgctatg aaagtctttt cagacccacg ctttaacatt
     3721 gatgtcttga aagttgaagt tcctgttaac attaaatatg ttgaaggctt cgctgaaggt
     3781 gaagtagttt atacacgtga agaagcagca gccttcttca aagcgcaaga tgaagcaacg
     3841 aacttgccat acatctactt gagtgctggt gtatcagcta aactcttcca agatactctt
     3901 gtatttgctc atgaatcagg tgcaaacttt aacggagttc tttgtggccg tgcaacatgg
     3961 gctggatcag ttgaagcata catcaaagat ggtgaaacag cagctcgcga atggcttcgc
     4021 acaactggat ttgaaaacat tgatgagctc aacaaagttc ttcaaacaac agcaacttca
     4081 tggaaagaac gtgtgtaaga aagtcctcct agtttaggaa catgaatcta aaaaaattta
     4141 aaaaaagttg tatgtaaagg tttacaaaat aacttacttg tgctatactt aaatcacaag
     4201 ttaatacaag gtgagtgtta ctaagtaata ttaggcatga tcacaggtga attagaaatc
     4261 agctgatttt ctagttcatt tgtggtcatt ttttgtactc atataccttt aagatataaa
     4321 aggaggttga catgtatcga attctaaatc caatgaatca caatgtctcg cttgtcagaa
     4381 atgataaggg agaagaggtg attgtaattg gtaaggggat tgcattcgga aagaagaagg
     4441 gggatttgat tgctgaaaat catgttgaga aaatctttcg gatgaagacc gaagagtcca
     4501 gagaaaactt tatggctctt ctcaaagatg ttccgcttga ttttatcaca gtgacctatg
     4561 aaatcattga taagctatca aagaaatatc attatccgat tcaagagtat ctctatgtaa
     4621 ccttgacaga tcatatttac tgttcttatc aagctctaac tcaaggaagg tacaaggata
     4681 gtaatctgcc agatatttct gctaagtatc ctgtcgcttt tcaaatcgca aatgaagctt
     4741 ttgaaattta ctgtcagaag ctagcagatc attttcctga ggacgaaatt attcggattg
     4801 cttatcattt cattaatgct gaaggtgaaa atgaagtgga acttgtggag tcgattgata
     4861 agaggaaaga aattctcagg aatgttgaag aagttttaac ggactatgca attcaacgaa
     4921 ctaaaaagaa taaccatttc tatgatcgct ttatgatcca tttgaattat ttcttggatt
     4981 atttagacag atctagagat gataaccaat cacttctgga tatggaagat catattaaac
     5041 aatcctatcc aaaagccttc gagattggtt ccaagatcta tgatgtgatt acgcaacata
     5101 cgggtcttga tttgtataaa agtgaacgag tttatctagt tctacatatc caacgtttat
     5161 tgtcataaaa atttatttaa aactatataa ggagaattct atcatgaata gagaagaagt
     5221 aacattgtta ggttttgaaa tcgtagccta tgctggcgat gctcgttcaa aactattgga
     5281 agccttgaag gctgctgaag ctggtgattt tgaaaaagcg gacgctctgg tagaggaagc
     5341 tggtagctgt attgcagagg ctcaccacgc gcaaacaagt ctattgacta aggaagcttc
     5401 tggtgaggac ttagcgtata gtgtgaccat gatgcatggt caagatcact tgatgacaac
     5461 tatcttgtta aaagacctaa tgcaccattt aattgaactt tacaagagag gagttaaata
     5521 aaatggataa gttaataatt tttattgaga aaggaaagcc tttctttgag aaattatcga
     5581 gaaatatata cttaagagcg ataaaagatg gttttatttc cagtatgcca gcagtattat
     5641 tctcaagtat ttttatacta atagctgctg tgcccaatat ttttgggttt aaatggtctg
     5701 atgaacagtt agcttttatt ttgaaacctt acaactactc aatggggatt ttagctctct
     5761 tagtagctgg gacaactgca aaatcgttaa cagattcagt taatacacgt agtatggaga
     5821 aaaccaacca aatcaactac atgtcaactt ttttagcagc tgttgttgga ttgttaatac
     5881 tggcagctga tccaattgaa ggtggatttg ctaatggtct tttaggtact agaggattac
     5941 ttactgcatt tttggcagct tttattacag taaatatcta taaagtatgt attaaaaata
     6001 atgtaaccat tagacttcct gaagaggttc caccaaatat tgcacaagtt tttaaagatg
     6061 ttattccgtt tgccttatct gttctttcaa tatatggatt ggatttaatt gttagaaata
     6121 tttttggtac aaatgtagca gaatctgttg gtaaaatatt agcccctcta ttttcagcta
     6181 ctgatggtta tatcggttta gctattgtat ttggtgctta tgctttcttt tggtttgttg
     6241 gaattcatgg gccatctgtt gtagaacctt taattgtagc tatcagttat gcaaatatag
     6301 aagctaatgt tcagcttgtg caagctggta tgcacgcaga taaaatttta aatccagtta
     6361 ctcaaacttt tgttgtaaca atgggtggta ctggtgcaac actagtagtt ccatttatgt
     6421 ttatgtggtt atgtaaatca aaaagaaata gaattgtcgg acgtgcgtct gtagttccta
     6481 ctttctttgg cgtaaatgaa ccaatcctat ttggtgctcc aattgtttta aatcctatct
     6541 tctttattcc gtttgttact gctcctatta tcaatgtttg gattatgaaa ttttttgtag
     6601 atgttctaca aatgaatagt ttcagtatta ttttaccttg gacaacacct gctccaattg
     6661 gtattgttat gggaacggcg ctggctccat tgtcattcgt cttggctata actttaatca
     6721 ttatcgacac tttaatctat tatccatttg ttaaagttta tgaccatcaa attttagaag
     6781 aagaacggaa aggaaactct tcatctgaat tgaaagaaaa agttgctgca aacttcaaca
     6841 ctgcaaaagc ggatgctatt cttgaaaaag cgggtgtaga agcagcacaa aatacaatca
     6901 ctaaagaaac aaatgtcctc gttctctgtg caggtggagg aacaagtggt ctccttgcaa
     6961 atgctttgaa taaggcagca gcagaataca atgtccctgt gaaagcagca gcaggcggct
     7021 atggtgctca ccgtgaaatg ttaccagagt ttgatcttgt tatccttgcc cctcaagttg
     7081 cttcaaactt tgaagatatg aaagcagaaa cagataagct cggtattaaa ctagcgaaaa
     7141 cagaaggcgc tcaatacatc aaattaactc gtgatggaaa aggtgctctt gcattcgtac
     7201 aagcgcaatt cgattaaggc tagagactct gaaatagtct cctatcgtta cggaaatcgc
     7261 tatggcgaat ttcctattat taattcgtcg gtaaaaagat atcgttttta cctcctcatg
     7321 tcacaattcg gtgacttggt acaagaagtg agatggagaa ggatggctca ttgactcctc
     7381 tcctctcact tttactttat ttaaatcaag aaataggtga aaaaaatgac aaaaacactt
     7441 ccaaaagact ttatttttgg tggcgcaaca gctgcctatc aagcagaagg tgctacacat
     7501 actgatggta aaggaccagt agcgtgggat aaatatcttg aagataacta ctggtacact
     7561 gcagaaccag ccagtgattt ttacaatcga tatccagttg acctcaagct agcagaagag
     7621 tatggtgtca atggtattcg aatttctatt gcttggtcac gtattttccc gactgattac
     7681 ggccaagtaa atgctaaagg tgttgagttt tatcataatt tatttgcaga gtgtcacaaa
     7741 cgtcatgttg agccttttgt aactcttcat cactttgaca cgccagaagc tctccactca
     7801 aatggagact tcttaaaccg tgaaaatatc gaacattttg tagactacgc tgccttctgt
     7861 tttgaagaat ttccagaagt aaactattgg acaaccttta atgaaattgg accaatcggt
     7921 gatggtcaat atttggttgg gaaattccct ccaggtatcc agtacgacct tgccaaagtc
     7981 tttcaatcac accacaatat gatggtgtct catgcacgcg cggtaaaatt gtacaaagag
     8041 aaaggctata aaggggaaat tggtgttgtt cacgccctgc caactaaata tcctctagat
     8101 cctgaaaatc cagcagatgt tcgtgcagct gagttggaag atatcatcca caataaattc
     8161 atcttagacg caacttatct aggtcgctat tcagctgaaa ccatggaagg tgtcaaccat
     8221 atcttatcag tcaatggtgg tagcttggat cttcgtgaag aagattttac agcattagaa
     8281 gctgcaaaag acttgaatga tttcctagga atcaactact atatgagtga ctggatggaa
     8341 gcctttgatg gagaaactga aattatccat aatggtaaag gtgaaaaagg aagctctaag
     8401 tatcaaatca aaggtgttgg tcgtcgtgta gctcctgact atgtaccacg cacggattgg
     8461 gattggatta tctaccctca aggtttgtat gaccaaatca tgcgtgtgaa gaaagattat
     8521 cctaactaca agaagattta catcactgaa aatggtctcg gctataaaga tgagttcgtt
     8581 gataacactg tttacgatga tggtcgtatt gattacgtga aacaacactt ggagatcttg
     8641 tctgatgcga ttgcagatgg agctaatgta aaaggttact tcatttggtc attaatggat
     8701 gtcttctcat ggtcaaacgg ttatgagaaa cgttatggtc tcttctacgt agattttgaa
     8761 actcaagaac gttatcctaa gaaatcagct cactggtaca agaaagtagc ggaaactcag
     8821 attatagact agtagaatta gtcattagat atagaatttt agtgagtcaa aaagatgttc
     8881 aaagatttta tccaatctat ttatgaaaaa aagtttatat tataaatttc gaaaaatgct
     8941 ctcaaatacc gtgtttgacg agtgaagaat tgaaaagtct tggaaaatgg tatgtctcga
     9001 ctgg
//
LOCUS       DAYYYC010000069         8961 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.069, whole genome shotgun sequence.
ACCESSION   DAYYYC010000069 DAYYYC010000000
VERSION     DAYYYC010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8961
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.069"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(298..1146)
                     /gene="dprA"
                     /locus_tag="ACHBV5_001932"
     CDS             complement(298..1146)
                     /gene="dprA"
                     /locus_tag="ACHBV5_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFM9967674.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLLTSGQDV
                     LAEFEF"
     gene            complement(1242..1931)
                     /locus_tag="ACHBV5_001933"
     CDS             complement(1242..1931)
                     /locus_tag="ACHBV5_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HFM9967675.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1943..2821)
                     /locus_tag="ACHBV5_001934"
     CDS             complement(1943..2821)
                     /locus_tag="ACHBV5_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFM9967676.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2811..3680)
                     /gene="licA"
                     /locus_tag="ACHBV5_001935"
     CDS             complement(2811..3680)
                     /gene="licA"
                     /locus_tag="ACHBV5_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HFM9967677.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3697..4719)
                     /locus_tag="ACHBV5_001936"
     CDS             complement(3697..4719)
                     /locus_tag="ACHBV5_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HFM9967678.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4724..5431)
                     /locus_tag="ACHBV5_001937"
     CDS             complement(4724..5431)
                     /locus_tag="ACHBV5_001937"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HFM9967679.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGNRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5767..7254
                     /gene="tacF"
                     /locus_tag="ACHBV5_001938"
     CDS             5767..7254
                     /gene="tacF"
                     /locus_tag="ACHBV5_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HFM9967680.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7264..8067
                     /locus_tag="ACHBV5_001939"
     CDS             7264..8067
                     /locus_tag="ACHBV5_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HFM9967681.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8069..8878
                     /locus_tag="ACHBV5_001940"
     CDS             8069..8878
                     /locus_tag="ACHBV5_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HFM9967682.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2814 a         1806 c         1518 g         2823 t
ORIGIN      
        1 aaagcgcaaa ctaggaagct agccacaggt tgctcaaagc actgctttga ggttgtagat
       61 aagactgacg aactcagctc aaaatactgt tttgaggttg cagatggaag ctgacgtagt
      121 ttgaagagat tttcgaagag tattatatga gaaaaatcct ctactctact aatccactta
      181 gaaaaaacgc atattagcaa gtgttaaaaa cttgctaata tgcgttttat tatggaaatg
      241 ttgggttcat tttctcttaa aattgatttt ttcttagaat tctagcttag gtcattttta
      301 aaattcaaat tccgcaagaa catcttgccc actggtgagc aattttgctc cttcttgaat
      361 caaatgatgg caaccgtctg atagtccatc taaaatgcta ccaggaatag caaagacatc
      421 gcgtccttct tccattgctc gctcacacgt aatgagacta cctgaacgca tcttagcctc
      481 tgctacaatc acaccacgac aaagtccagc aatgatgcga ttacgggcag gaaaatgaaa
      541 tttcagaggt tgttcgccag gtccatattc acttagaacc agatggtcat tgccgatgta
      601 gtcttgcaag cgtttattgg ctttaggata aaacacatcc agtcctgttc caatcactgc
      661 aatggttttt ccgccattct gaagagctgc catatgagct gctgtgtcaa tgcccttggc
      721 cagaccactg acaataacca gttcattttc caagccttga atgacttttt caactgactt
      781 agctccctgt ttgctacaag cacgactgcc cacgaccgct accttcggga atttcaggag
      841 gtcaagattt cccttgtaaa ataaaagtac aggcgcatca tatatttcac tcaaatccca
      901 aggataacag tcatctaaaa tagagaaaga tggaaatttt tgaaactctt tcgacaaatg
      961 cgcatcgtct atctgaaaat aacgttccat aaaaacggct ggattacggc aacctgatat
     1021 atctgcaata tcacccaaca aaagctcctg atcaacattt tcaccgtatt ctagcacttt
     1081 caaaatctgt tgattggtca aacctgattt ttttaactta tagatttcat agtttgtgat
     1141 tttcataaat aactccattt ctttttctac tcatctatct attcgtaaaa gttcgtaaaa
     1201 aatcaaaaaa catccgacta ttttgtcaga tgttggaatc tttaattttc gtttttaaga
     1261 atttcttcta atttacgata gtcttggaca ctatcgatct cataaatgct attgccttct
     1321 aattcttcaa catagacatc tagctctttg atattatcct taaccatatt gtcccaatag
     1381 agatcaacaa attcaccact tgcataagcc ttgtcgataa agctgacaat cttttctgca
     1441 gttggagcat cccagaagga tacaccacta aggatgcgac ctgccttgct atcaacaata
     1501 atgtcttgaa ccttgtagtc atctccatag accaagaacc attcgttggt acaatcttca
     1561 cgataaacac taaaataagt cgaacgtgtc aaatcattgc ggaacatatt tttaaagaga
     1621 taattgtcag catcaataac atagctgttg gccaattctt cttttacaag atagagagag
     1681 taaaagttat tgtagtcagc gtatttatca ttgaaaacga ggcgaacacc gtatttttct
     1741 tttaagtaat cgaattgttc tttaagataa ccaacaatga tgatgatgtc attgattcct
     1801 ttttctttga gaaactcaat ttggtattca atcaaaggtt tttgattaac ctgaaccaag
     1861 gctttagggg tattttcagt cataggacgc aagcgagttc ccaatcccgc tgctaagata
     1921 atggctttca cacgaatctc ctttattctt taataataat ataaactcca gcaatgacga
     1981 caagtgacgt cataatggtc agcatatcta gcggtgcacc caaaaaaaca actgcaaaca
     2041 agaccgtcca tactacatag ctcacgttca agcctgtagc cttggctggt tgcaagcgat
     2101 tgatagcgat ataataagcc aagtaggaaa tcatatcaaa ggctgcaaaa acaatcatga
     2161 gacctagcaa ttgtccattg gctactgcag taaatgactg atgagagaag agcacaatca
     2221 caagatagga caagaacgaa gtcacttgac ggattaagag ggcttcgatt tcactcagtt
     2281 cactttccat agcaaaggag ctaagaacac tctcacttcc ccatgcaata gcacaaacca
     2341 aagcacagag aatcccaatg tagaaggaat taacctgttc aaccttatag gtctgggcaa
     2401 taatccctcc aataatcaag acaatcccaa atacagtatt tttcgaaatc ttgtgcttca
     2461 aaaagaagaa agccaataga actgaaatcg cagggtaaat agccgataca gatgaagcta
     2521 aagaacttcc gatatactta actgcataaa gattggcctg cataccgata gggcctgcta
     2581 gcaaggctcc gatgataaca ctgacattgc gaatatttaa gaaaattgag aggcgaactt
     2641 tcccttcttt taccaagaga aaagctagta agataaagat gctcaaaaaa tcatgagctg
     2701 cagccaccac aaagggtgac aaatctgtaa aaatcgaaaa gatataagca ctaaccgtta
     2761 gacccaagcc ccagaaaata cctgagagaa ggccaaaagg aactccgttt ttacttttca
     2821 tctgaacctc cataagaagc caaaccttta acagctcttt ggtaacgatt cacaccatag
     2881 tcaccaaaat cttcaccttg ctcttcctta tagacagtcc atagactcca aatagtatct
     2941 tgtaaaattt tataaatagc aatcttttca tgagaaaccg gtgtttggtc actctcatag
     3001 tgagataaga aagtttcttc ctcttgggaa gtgaattcag actctaaaaa gagggcagcc
     3061 aaatcccaca ttggatcatt cattgatgaa tattcccagt caatcaaata aagtcgtcct
     3121 tgaggtgatt cgataaagtt ttcaggcacc aaatcgatat gacaagattt tctgtcaaca
     3181 cctaagtcag ccagtctttt ctctaaggag aagactgcat ttctaacaga ttcatagttg
     3241 gcataaggaa tttgttcttc aatcaaggat tcgtattttt tgatttcttc aaaaggagca
     3301 aattctcctc ttaattcctt agcagacgta tgaatagttt gtaatattgg agcaattttg
     3361 tcgaacttgg tcttgattga cgttgaatca agcgtaatcg cagattcgat atactcattt
     3421 actttgatac cagcttcaat atcaaaaaga taatttttta catctaagcc taaatccttt
     3481 agtagttcaa gattgtactt ttcatcttgt cgattgataa gcttttctgt ccctttacca
     3541 aagaatttaa caatgtattg cttatttgtt gttttggcca aatagttttg attggtcatt
     3601 ccacccagtt gttcaacact gaggacttcc tcttcttgac taagtaagga agaaattttt
     3661 tctttaatga ttttctccac aattaacctc cagtacttat acttcccact taaacactgt
     3721 tttaaaggct gtgtttaaat cggttgcaaa gacacgatga atatctttaa tttctcttac
     3781 aggttcttct agataaagga tatttttaag acgattggca aatttcttga cttccatcat
     3841 ttggatagca tttttaaaat caatgcgacc agaacgagat gacccaacca aaatcaagcc
     3901 cttttctaag gcatcgcgag tattgagatt gactttatat tcgctaactc ccatcatgag
     3961 aatcgttccc tgaggacgaa tgtagcgaat caagtcatta atagctggtc cagtaccatc
     4021 accaccacaa cattcaaaag catggtcaaa ggccaactct tcaggaatat tatccgtaat
     4081 atagcattct ttggcaaatg agaagagttc caacttttcc caatgacgac caataaccac
     4141 aatctctgat tctggcaaag tatagttgat aatattggca accacaaaag ctaaacttcc
     4201 atctccaata acggcgatcc gctcccgctt gctatgagca agagtcaata gacgattcat
     4261 agcgtgcatg cccacactga caaactctgt aatggctgca accgtatctt caatagcatc
     4321 ataagccacc acacgatctt tagggagaga aacaaactct ctcataaagc catcaaatcc
     4381 actagacaag aaatgggtcc ctgtcatgta gttttcatag aattcttcat cactctgcat
     4441 aggagactga ttgggaatca tgacaacttt ttgaccaacc tcgtaggttc cggtcgggtc
     4501 agaaatgacg gttccacatg actcgtgaat cattgccatt ggaagctttt tattcaaaat
     4561 cttgggatca cgttttccct gatagtaacg ctgatccgca tgacagacag ccatgtagtt
     4621 gggacggata aggatatgat tctcttggtc aatagcctct tcctgatatt tgacattgat
     4681 aaacttaggc ttagttagtt gataaatttg attaatcatt ttactagtct ttctcaatca
     4741 tactttttgc aatcttcaaa tctgttacgg ttgtaatctt cagatttgag tattcacctt
     4801 tggccaaggc cacatctttt cctttgatca caaagatttt acatgcatct gtcaagattt
     4861 ccttctcttc atcagaaaga gatccataaa ggtccatgaa gtccttgcaa cggaatgttt
     4921 gaggtgtttg tccttgataa aggtgagcac gatttggaat atctgtaata aattgaccat
     4981 tggtactttc aacgatagta tcaaccgctt ctaccactgt gtccactgcg tcatgatttt
     5041 gggcaagttg gatattgtcc tgaatcatgc gaagtgtaat aaatggacga acagaatcgt
     5101 gggtaacaac gatatcctct ggagtaagcg gacgataagc atcaatggct tcaatgattt
     5161 tcttaatact tgtattgcgg tcagcaccac cctttgtaat gatgatacgt tccttataaa
     5221 gaggaagata tttatctaca agatcttctg catgagaaac ccagtctcca tgaacaccaa
     5281 ctacaatttt ttcaatactt ggctccaaga caaatttttc aattgtatga atcaaaatag
     5341 gtcgattacc tagctctaaa aattgttttg gcaagttact gatccccatg cgtgtgccag
     5401 ttccaccggc aagaattcct gcataaatca tctattttct cctttgtctt actaaaaaaa
     5461 cttattctct ctattatacc acaatctagt cctatcataa aagaaatact ggtcctcccc
     5521 ttctagaata ggagaattat gcagttctat tattcaaaga aactagtcca tttctagtaa
     5581 tgactaggaa ttctgtagca attactaata aatggctgcg aaattttaga gtccttcaga
     5641 ataatatact ttccttaaag aaaacttaaa acttaagatt tgaaacttca aagtgattac
     5701 ttgacttact gcccttcatt tcttattagc taactttatg atataatgaa aaacgaggta
     5761 aattgaatga aaagtataaa attaaatgct ctatcttaca tgggaattcg tgtcttgaat
     5821 attatttttc ccatcctaac tggaacctat gtcgcgcgtg tcttggaccg aactgactat
     5881 ggttacttca actcagtcga cactattttg tcatttttct tgccctttgc aacttatggt
     5941 gtctataact acggtttaag ggctatcagt aatgtcaagg ataacaaaaa agatcttaac
     6001 agaacctttt ctagtctttt ttatttgtgc atcgcttgta cgattttgac cactgctgtc
     6061 tatatcctag cctatcctct cttctttatt gataatccaa tcgtcaaaaa ggtctacctt
     6121 gttatgggga ttcaactcat tgcccagatt ttttcaatcg aatgggtcaa tgaagctctg
     6181 gaaaattaca gttttctctt ttacaaaact gccttcatcc gtatcctgat gctggtctct
     6241 attttcttat ttgttaaaaa tgaacacgat attgttgtct atacacttgt gatgagttta
     6301 tcgacgctga ttaactacct gattagttat ttttggatta aaagagacat caaacttgtt
     6361 aagattcacc taagtgattt taaaccactc tttctccctc tgacagccat gttagtcttt
     6421 gccaatgcca atatgctctt cactttttta gatcgcctct tcctcgttaa aacagggatt
     6481 gatgtcaacg ttagttacta taccatagct cagcgaattg tgaccgttat agctggggtt
     6541 gtaacaggtg caattggagt gagtgtgcct cgtctcagtt actatctggg gaaaggagac
     6601 aaagaagcct atgtttctct ggttaataga ggtagtcgaa tctttaactt ctttatcatt
     6661 ccactgagtt ttggactcat ggttttagga ccaaatgcca tcctacttta cggtagtgaa
     6721 aaatatatcg gaggcggcat cttgacctct ctcttcgctt ttcgtacgat tatcctggcc
     6781 ttagatacca ttcttggttc ccaaattctc tttaccaatg gctatgaaaa acgtatcaca
     6841 gtctatacag tctttgctgg gctactcaat ttgggcttga atagtctcct ctttttcaac
     6901 catatcgtgg ttcctgaata ctacttactg acaactatgt tatcagagac ttctctactt
     6961 gttttctata ttattttcat ccatagaaaa caactcatcc acttgggaca tatctttagc
     7021 tatactgttc gatactctct cttttcactt tcctttgtag caatttattt cctgattaat
     7081 ttcgtgtatc ctgtggatat ggtcattaat ttgccatttt taattaatac tggtttgatt
     7141 gtcttgctat cagctatctc ttatattagt ctacttgtct tcacaaaaga tagcattttc
     7201 tatgaatttt taaaccatgt cctagcctta aaaaataaat tcaaaaaatc ataggagttt
     7261 aaaatgaaac aactaaccat tgaagatgcc aaacaaattg aattagaaat tttggattat
     7321 attgatactc tctgtaaaaa gcacaatatc aactatatta ttaactacgg tactctgatt
     7381 ggggcggttc gacatgaggg ctttatccct tgggacgacg atattgattt atccatgcct
     7441 agagaagact accaacgatt tattaacatt tttcaaaagg aaaaaagcaa gtataagctc
     7501 ctatccttag aaactgataa gaactacttt aacaacttta tcaagataac cgacagtacg
     7561 actaaaatta ttgatactcg aaatacaaaa acctatgagt ctggtatctt tatcgatatt
     7621 ttccctatag atcgctttga tgatcctaag gtcattgata cttgttataa actggaaagc
     7681 ttcaaactgc tgtctttcag taaacataaa aatattgtct ataaggatag ccttttaaaa
     7741 gattggatac gaacagcctt ttggttgctc cttcgaccgg tttctcctcg ttattttgca
     7801 aataaaatcg agaaagaaat tcaaaaatat agtcgtgaaa atgggcagta tatggctttt
     7861 attccttcaa aatttaagga aaaggaagtc ttcccaagtg gtacctttga taaaacaatc
     7921 gatttaccct ttgagaattt aagccttcct gcacctgaaa aatttgatac tattttgaca
     7981 caattttatg gagattatat gaccctacca ccagaagaaa aacgcttcta cagtcatgaa
     8041 tttcacgctt ataaattgga ggattaggat gcaatattta gaaaaaaaag aaattaaaga
     8101 aattcaacta gccctgctgg actatattga tgagacttgt aagaaacatg atattcctta
     8161 ttttctcagt tatggaacca tgcttggagc catccgccac aaaggtatga ttccttggga
     8221 tgatgatatt gatatttccc tttatcgtga ggattatgag cgtttactga agattattga
     8281 agaagaaaat caccctcgct acaaggttct ttcctacgat acatcttctt ggtacttcca
     8341 taatttcgca tcgattttgg acacttctac tgttatagaa gaccatgtta agtacaagcg
     8401 tcatgatacc agccttttca tcgatgtctt cccaattgat cgatttacag acttgagcat
     8461 tgtcgacaag agctataagt atgtggccct tcgtcaacta gcttatatca aaaaatcacg
     8521 agcagttcac ggtgatagca aactaaaaga ttttcttaga ttatgtagct ggtacgctct
     8581 ccgatttgtc aatcctcgct acttttacaa gaaaattgat caactagtca aaaatgctgt
     8641 aaccaacact cctcaatatg aaggaggagt tgggatcggt aaggaaggga tgaaagaaat
     8701 cttcccagtt gataccttta aagaactgat tttaactgag tttgagggcc gtatgttgcc
     8761 tgttcccaaa aaatatgacc aatttttaac ccagatgtat ggcgattata tgacaccacc
     8821 atcaaaagaa atgcaagagt ggtatagtca tagcattaaa gcttatcgca aaaactgatt
     8881 gagggggatt atacaaacta ctaagataga ggttattcaa aaacataatt ttagtagaaa
     8941 atgaaatata tattcccaca a
//
LOCUS       DAYYYC010000070         8527 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.070, whole genome shotgun sequence.
ACCESSION   DAYYYC010000070 DAYYYC010000000
VERSION     DAYYYC010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8527
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.070"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(<1..201)
                     /locus_tag="ACHBV5_001941"
     CDS             complement(<1..201)
                     /locus_tag="ACHBV5_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM9967683.1"
                     /translation="MKSTKEEIQAIKTLLKDSRTAKYHKRLQIVLFRLMGKSYKEIIE
                     LLDCNQTTIWRNVKKYEEFGLDS"
     gene            543..1889
                     /gene="gdhA"
                     /locus_tag="ACHBV5_001942"
     CDS             543..1889
                     /gene="gdhA"
                     /locus_tag="ACHBV5_001942"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFM9967684.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSNLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGVV"
     gene            complement(2178..5756)
                     /locus_tag="ACHBV5_001943"
     CDS             complement(2178..5756)
                     /locus_tag="ACHBV5_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFM9967685.1"
                     /translation="MSLRNKIEQHIKELEGGKFQKLGDAYLSRKYNFNIVSLGSQEGT
                     DKTTKGIPDSYAVENGKYVYIMYGTHKSVISKLEGDIQSVKKKILEENIAEDKVGRLI
                     CCHTSSNITIKQKEDLEKMAEPYHLELIGINEIANDLTKIDFQYLAKEYLSISESTEQ
                     VWSINDFIRIHDESKTNAPISNDYIGDVSEIINTIKSSEKRIFLISAKPGTGKTRLAI
                     EICFLLDRNKYNIICVKSNNQDIYQDVKRNLNLHKENIVFIDDVNTTQNYISTLGLLN
                     TTSNIRFILTVRDYAKKDVINNIKVYGYNNIEPELIKDDNFKELLNQFSRNDFTNQEI
                     EHIKTISKSNPRIAVIAAKLSSSQDLTNFNDEIDILKDYYEEILNKNNIIYAEQKTLF
                     ILSYLKKIRLESLEENQEFNKLLKITDITNTDFKSAVEKLHERELCNIYNDKIVKIAD
                     QSLDDYIVIKFLINKKISILEILHELYPVNDQRVVQILNQCSNFIRKESDLEGVSDAV
                     KSYYYNESNFESDELKEKFLIQFGVLLPLEAISHVKNKIDNIESQVYTKTNFINQKDK
                     KGSIEDSVLNIVFVTTRTKYCSQILQLLLKYFDKNPNKISEVYSILEANYGLVTEREY
                     IDYTLAENTISELANLDLTKSYNQELIVTILKQFLKIEIERTETHEEKFTFGRYKVPD
                     SEKLKQYHRSILKLLANLYNIGSCETRFYIEKMLYDYRRKILTYSESHRNTIFGDLRN
                     IRKLFFNDIKNLSMIGEKIVYALHKAEVKENLPIVFDDYIISDRQKIYNNLTNPNHAW
                     FYDASEIKLQQIANSYSNVWLKIFNFANQFKHSLFMNDNNIELVLFNMFLLSKNDKKI
                     KFLNYMFKSNYHFVNMNPISFLENIEESSMQSVIVSSPESEKYEWQLAYLTQLENVKN
                     EDLQTLKSILEANSLPCYFTILNFERLILKDPSLKELLIQKAGNTNFVISDFIREEEV
                     PKLINLIGVKELKFWYLINLENCQNHSYNLFQKLGEKDVDFSVEVLKKIDELRIGHSN
                     LGYMVLHSISEFRDKKEIYKKFIRFAINRPYYYYNNMIDDIIKNDSQIILEILEETNN
                     EQSAIRLVNLGVEFLENNNQKLILFNLLRAKGFGKKSFQEIHFTPYSHFYTDSHVPVL
                     ELEKELLERIKKIFETGIDYINLLLYLNKLIDCKRKAIERELEKEF"
     gene            complement(6003..6371)
                     /gene="rplL"
                     /locus_tag="ACHBV5_001944"
     CDS             complement(6003..6371)
                     /gene="rplL"
                     /locus_tag="ACHBV5_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFM9967686.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            complement(6447..6947)
                     /gene="rplJ"
                     /locus_tag="ACHBV5_001945"
     CDS             complement(6447..6947)
                     /gene="rplJ"
                     /locus_tag="ACHBV5_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFM9967687.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     misc_feature    complement(6986..7121)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(7197..8456)
                     /locus_tag="ACHBV5_001946"
     CDS             complement(7197..8456)
                     /locus_tag="ACHBV5_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HFM9967688.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
BASE COUNT         2632 a         1561 c         1318 g         3016 t
ORIGIN      
        1 agagtcgagt ccgaactcct catatttttt tacatttcgc caaatcgttg tttgattaca
       61 gtctaaaagc tctataatct ctttataaga tttgcccatc agacgaaata gaacgatttg
      121 aaggcgttta tgatatttag ctgtacgaga gtcttttaaa agtgttttga tggcttggat
      181 ttcttcttta gttgatttca tatcactatt atataatgct ttttgatttt agtctggtat
      241 aaatattgct ttcctccaaa atggtcataa ttttactagc aaatctaaca tatcacggat
      301 aaattaacaa gtgatttctg aattgctaaa cattttcttt tcttatagca taccatactt
      361 taagattttg tctttgagaa agatatttcc aagaaaaacg ttcgtttttt tatctatttt
      421 caaaaaaaac caaaaactga attgaaagaa tttttagaaa atttctgttt tttctttaca
      481 gtgaaaaaaa attctgctat aatgtcttat gtaataaaat atgacaataa aaggagaacg
      541 atatgacatc tgctaaagaa tatatccaaa gcgtgtttga aactgtaaaa gctcgtaacg
      601 ggcacgaggc tgaattcctc caagctgttg aagaattttt caacactttg gaacctgtat
      661 ttgaaaaaca ccctgagtat atcgaagaaa atatcttggc acgtattact gagcctgagc
      721 gcgtgatttc tttccgtgtt ccttgggttg accgtgatgg aaaagttcaa gtaaaccgcg
      781 gctaccgtgt tcaattcaac tcagctgttg gaccatacaa aggtggactt cgtttccacc
      841 caactgtaaa ccaagggatc ttgaaattcc tcggatttga acaaatcttt aaaaatgtct
      901 tgactggact tcctatcggt ggaggtaaag gtggatcaga cttcgatcct aaaggtaaaa
      961 cagatgctga agtgatgcgc ttctgccaaa gcttcatgac tgaattgcaa aaacacatcg
     1021 gaccatcact tgacgtacct gctggtgata tcggtgttgg tggacgtgaa attggttacc
     1081 tttacggtca atacaaacgt cttaaccaat ttgatgctgg tgtcttgact ggtaaacctc
     1141 ttggatttgg tggtagcttg attcgtccag aagcaactgg ttacggtttg gtttactata
     1201 ctgaagaaat gctcaaagct aacggtaaca gctttgctgg taagaaagtc gttatttcag
     1261 gttctggtaa cgttgctcaa tacgctcttc aaaaagcaac cgaacttggt gcaacagtta
     1321 tctctgtttc tgactcaaac ggctatgtta tcgatgaaaa cggtatcgac ttcgatcttt
     1381 tggttgatgt taaagaaaaa cgtcgcgctc gtttgactga gtatgcagct gagaaagcaa
     1441 ctgctactta tcatgaaggt tctgtatgga cttacgctgg aaactatgac attgcgcttc
     1501 catgtgctac tcaaaacgaa atcaacggtg aagcagctaa acgtttggtt gctcaaggcg
     1561 ttatctgtgt atctgaaggt gccaacatgc caagcaacct tgatgccatc aaagtttaca
     1621 aagaaaatgg tatcttctac ggacctgcca aagctgccaa cgctggtggt gtagccgttt
     1681 cagcccttga aatgagccaa aacagccttc gcctctcatg gactcgtgaa gaagttgatg
     1741 gacgtctcaa agacatcatg accaacatct ttaacacagc taaaacaact tcagaaacat
     1801 atggtcttga taaagactac cttgcaggag ctaacattgc tgcctttgaa aatgtagcaa
     1861 acgctatgat tgcacaaggc gtggtataaa aaaaaattac ggaaactgac tacccagacg
     1921 ggtagccagt tttttcaatt cctaaaattt aagattctaa taccctttat gcaaaaatat
     1981 agaattctac ctttttcttt atataggcta atgtttttaa tatatttatt gtctattttt
     2041 gaaaagacaa taaaactatt ctactataga ttatcatttc ccacaattca taactcaaac
     2101 ctaatatttt gttataaaac agtagatttt atttattata tctggcacct taaaaagtaa
     2161 gaaatataaa ttaaaattta aaactctttt tccaattctc tttcaatagc ttttcgcttg
     2221 caatcaatta gtttattcaa gtacagtagc aagttaatgt agtctatacc cgtttcaaat
     2281 atctttttaa ttctttctag gagttctttt tctaattcca acaccggaac atgactatca
     2341 gtataaaaat gtgaataggg agtaaaatgt atttcttgga atgacttctt accaaatcct
     2401 ttagctctga gaagattaaa tagtattagt ttttgattgt tgttttctaa aaattctaca
     2461 cctagattga ccaatctaat tgcagattgc tcattatttg tttcctccag tatttctaat
     2521 atgatctgac tgtcattttt tataatatca tcaatcatat tattgtagta gtaatatggc
     2581 ctatttattg caaaacggat aaacttttta taaatttctt tcttatctct aaattcactt
     2641 atagaatgta ataccatgta tcctaaattg gaatgaccta ttctcaattc atcaattttc
     2701 ttcaatactt ctaccgaaaa atcaacatct ttttcaccta atttttgaaa aagattatag
     2761 ctgtgattct gacaattttc taaatttatt aaataccaaa acttcaactc ttttactcca
     2821 attagattta ttaattttgg cacctcttct tctcttataa aatcagaaat aacaaaattt
     2881 gtattcccag ctttttgtat taacaactct tttaaactag gatctttcaa aatcaatctc
     2941 tcaaaattta aaattgtaaa ataacatggt aaagaattag cttctagaat actctttaat
     3001 gtttgtagat cttcattttt aacgttttca agttgtgtta aataagcaag ttgccattca
     3061 tatttttctg attctggaga ggaaacaata acagactgca ttgaactttc ctcaatattt
     3121 tctaaaaaac taatcggatt catatttaca aaatgatagt ttgatttaaa catataattt
     3181 agaaatttaa tctttttatc attttttgat agtaaaaaca tattgaatag tactagctca
     3241 atgttattgt cattcataaa taagctatgt ttgaattgat ttgcaaaatt aaaaatttta
     3301 agccaaacat ttgaatagct atttgcaatt tgttgtagtt taatttcaga agcatcataa
     3361 aaccaagcat ggttaggatt tgttaaatta ttatatattt tttgtctgtc agaaattata
     3421 taatcatcaa aaacaatcgg taaattttct ttcacttcgg ctttatgcaa agcataaact
     3481 attttttctc caatcataga taagttttta atgtcattaa aaaataattt cctaatattt
     3541 ctcaaatctc caaagatagt attacgatga ctttctgaat aggtcaaaat ttttcttctg
     3601 taatcatata gcattttctc aatataaaat ctagtttcac aactccctat attatacaaa
     3661 ttcgctaaaa gttttagtat acttctatga tactgtttta atttttcact atccgggact
     3721 ttatagcgcc caaaagtaaa tttctcttca tgagtctctg ttctttcgat ttcaatttta
     3781 agaaactgct tcaaaattgt cacgattaat tcttggttat aacttttcgt caaatcaaga
     3841 ttagcaagtt cagaaatggt attttcagct aaggtataat caatatattc tctttctgta
     3901 accaacccgt agtttgcttc aagaatacta taaacctcag aaattttatt aggattttta
     3961 tcaaagtact ttaacaataa ttggagaatt tgactacaat attttgtccg tgtagttaca
     4021 aatacaatat ttaaaactga atcctcaata gatccctttt tatccttctg attaataaaa
     4081 ttagtctttg tataaacctg agactctata ttatcaattt tatttttaac gtgtgaaatt
     4141 gcttctaaag gaagtaatac tccaaattgt attaaaaact tttctttaag ttcatcactt
     4201 tcaaaattac tttcattgta ataatatgat ttaactgcat cagaaacgcc ttctaaatca
     4261 ctctctttcc taataaaatt ggaacattga tttagtattt gaacaactct ttggtcgttt
     4321 actggatata actcatgtaa aatttctaaa attgatattt tcttgttaat taaaaacttg
     4381 ataactatat aatcatctaa tgattgatct gctatcttta caattttgtc gttataaata
     4441 ttacacaact ctctttcatg aagcttctcc actgcactct taaagtcagt atttgttatg
     4501 tcagttattt ttagtaattt attgaattcc tggttctctt ctaaactttc cagtctaatc
     4561 ttttttaagt aagataaaat aaatagagtc ttttgttctg cataaataat gttgttttta
     4621 tttaaaattt cttcatagta atcttttaaa atatcaatct catcattaaa attagtcaaa
     4681 tcctgagagc tagataactt tgctgcaatg actgcaatac gcggattgct tttagatatc
     4741 gtttttatat gttcaatttc ttgattggta aaatcgtttc gagaaaattg attgagtaat
     4801 tccttaaaat tatcatcttt tataagttct ggctcaatat tattgtaccc ataaacttta
     4861 atattattga ttacatcttt tttagcataa tcacgtaccg taagaataaa ccgaatatta
     4921 ctagtcgtgt tcagtagccc aagtgtagaa atataatttt gtgtagtatt aacatcatca
     4981 ataaaaacaa tattttcttt gtgtaaattt agattgcgtt ttacatcttg gtaaatatcc
     5041 tgattattgc tcttgacaca aataatgtta tatttatttc gatccagcaa aaagcaaatt
     5101 tcaattgcta atctagtttt ccctgttcca ggcttagcag atattaagaa gattcgtttt
     5161 tcacttgatt taatggtatt tataatttca cttacatctc caatatagtc atttgatata
     5221 ggagcattag ttttactctc atcatgaatt cttatgaagt cattgataga ccaaacttgc
     5281 tctgtagatt cactgattga tagatactct tttgctaaat attgaaaatc tatctttgta
     5341 agatcattag caatttcatt aattccaatc aattctagat gataaggctc agccattttt
     5401 tctagatctt ctttttgttt aattgttata tttgaagaag tatgacaaca aataagtctc
     5461 ccaactttat cttcagcaat attttcctct aaaatttttt tcttaactga ctgaatgtct
     5521 ccttctaatt tagatattac agacttatgg gtgccataca taatataaac atatttacca
     5581 ttttcgacag cgtaagaatc tgggatccct ttagttgttt tatctgttcc ttcctgtgag
     5641 cctaatgaaa caatattaaa attgtatttt ctacttaggt acgcgtcacc tagtttttga
     5701 aacttccctc cctctagctc tttaatatgt tgctcaattt tatttcttaa actcattata
     5761 aaaacctttc cagataagta tttcaacata attatatcac actagtcaaa accataaggt
     5821 atagtttaat taacaaactc ttgtactacg ttaatttaga gtagtaaacc aattatacaa
     5881 aaattattta tttcctaaac aactatataa aaagtttgcc cctttttaaa caaaaagaaa
     5941 aaccgctact cctaagaata gcggtttaat catgttttta agctactaat gtagttgctc
     6001 tattatttaa gagtaactga agctccagct tcttccaatt tagctttgat ttcttcagct
     6061 tctgcagttg caacgccttc tttaacaagt gctggtgcac cgtcaacaag ttctttagcc
     6121 tctttaagac caagaccagt gatttcacgt acaactttga taacgccaac ttttttgtcg
     6181 cctgcagatg tcaattcaac gtcgaatgaa tctttagcag caccagcatc agctgcatca
     6241 gctgcagcaa cagctacagg agcagctgca gttacaccaa attcttcttc gatagctttt
     6301 acaaggtcgt tcaattcaag gattgaagct tctttaattt cagcaataat gttttcaatg
     6361 ttcaatgcca ttgttatttc ctccaaataa gttttaaatt ttataatagt ttttttcgta
     6421 gctaggctac gctgtgtagc ttaagattaa gccgcgtctt ctttgctttc tgcaaccgct
     6481 ttgactgcaa gagcaacgtt gcgcactggc gcttgaagta cagaaaggag catagaaaga
     6541 agtccttcgc ggtttggaag agttgcaagt gcaagaatct cttctttaga tgcgacagcg
     6601 ccttcgattg caccaccttt aatttcaagt gcttcagcgt ttttagaaaa gtcgttcaag
     6661 attttcgctg gtgcgataac atcttcatta gaaaatgcta ctgcagatgg tccaacaaat
     6721 acagatgcaa gatcttcaag accagctttt tcagctgcac gacgcaagat tgagttttta
     6781 ataactttat actcaacttc gcttccacga agctcacgac gaagaactgt atcttgctca
     6841 actgtcaaac cacgagcgtc tacaacgacg atagatgcag cagctttcat tttttcagct
     6901 actacgtcaa ctagttccgc ttttttagca ataattgctt cactcattag tgtgttcacc
     6961 tccgtaatta ttttgcttgg ggaatttttc aaaaagaaaa acgcgcccaa acctagacac
     7021 gaaagtacaa tacgcttctt tttacatgat acgttttgtc ctcggtagga tatttatgag
     7081 tcgagctccc ctactgtctt aggcagtttt tttaaaccgt atataagtat agcatagtca
     7141 aaaaaagaat gcaagatttt tgcaaacttt ttttaaaatt tttcgtaatt tttcttttaa
     7201 agttctactg tcaggacttg accttgctta acaacctgtt ctccggcgat ataaacatca
     7261 tctacatcac tagatttaac tgcataaacc aggtgagaca gcatattttc ctgaggttgg
     7321 agatgaattt tcccttgtgg ttgaatgacc agaaaatctg cttgcttgcc gacttccaga
     7381 cttcctatct gattttccat tccaaggacc ttagcccctt cgattgtcag taccttgaga
     7441 gctgtttcga ttggaaactg gctggcatcc ccacttttca tcttctgaag aagagctgca
     7501 gtccttcctt cctcaaacat atctagattg ttattggaag caaccgagtc agtcgcaatt
     7561 ccgactgcta ctcccgcttt ttggagctgg ataattggag caattcctga tgccagtttg
     7621 aggttactga taggattgtg ggcgatagcc acttgagaag atgccaagcg ttcaatttct
     7681 ctctcgttta attcgacccc gtgagcaaat acggacggat gatctaaata acccagttct
     7741 tcaagaaaag caagggggcg tttgccgtat cgtttgagga taattcctga ctcctccttg
     7801 gtctccgcca catggacatg gagcggaata tttagctctt ttgccatttc caaactcgct
     7861 tccagcaagt ctctactgca gctatacgga gaatgaggtg ctaccataac cttgaaattt
     7921 ggatttttat attttaagat ttcatctatg atggatcgag ttctgcttat agtctcagca
     7981 gttgtttctg tctctgaaga aaagagagtc ggagaaaaat aacaacgcat cttggaagtt
     8041 ttcaccacct gataaatttg ctggatatcc acaccattgg gattatacat atcgttaaag
     8101 gttgttgttc ctgactggag catctctgtt agggcttctt taaccgcatt ggtagtcatg
     8161 tcgggagtaa actcagattc tgctggccag atatagtcat tgagccattc atggagattg
     8221 ctgtcatctc ggatccctct cagacctgtc attgcagaat gggtgtgaca attgaccaaa
     8281 ccaggcataa tccaagctcc ctgatagtct ataatctgct cagcttgttc taaaaacgct
     8341 ggcttatctt gaccgacata gacgatttga gaatccttga ctgctaagat tccatcaaga
     8401 taaacatgga aattttgatc acaagtcacg atatttacat gctgaaagac tttcattata
     8461 ggctcctttt ctaaaagaca agttgtactc tcttcaaacc acttcagatt cactttgccg
     8521 taggtgt
//
LOCUS       DAYYYC010000071         8411 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.071, whole genome shotgun sequence.
ACCESSION   DAYYYC010000071 DAYYYC010000000
VERSION     DAYYYC010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.071"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            84..788
                     /locus_tag="ACHBV5_001947"
     CDS             84..788
                     /locus_tag="ACHBV5_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HFM9967689.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            769..1698
                     /locus_tag="ACHBV5_001948"
     CDS             769..1698
                     /locus_tag="ACHBV5_001948"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HFM9967690.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSK
                     NNKYLEKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            1695..3803
                     /locus_tag="ACHBV5_001949"
     CDS             1695..3803
                     /locus_tag="ACHBV5_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HFM9967691.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVAS
                     LKYIMDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAILDL
                     LMIVVYAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNLIDKNIKEKVNVQNITS
                     EVISKNSDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSITNVLQIILPVLT
                     LIVGVNIKTFEQLTLGQIVAISTVSPYFISPIISLSDNYIQLMLLKGYFLRIEDVFNT
                     KSELIPERVSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVGESGSG
                     KSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLTF
                     GHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSKP
                     SVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVEI
                     GTHRELLELGGIYKQLYSNN"
     gene            3827..5239
                     /locus_tag="ACHBV5_001950"
     CDS             3827..5239
                     /locus_tag="ACHBV5_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HFM9967692.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYK
                     LKDQPYNYMFVKKFWKKHYQ"
     gene            5293..5565
                     /locus_tag="ACHBV5_001951"
     CDS             5293..5565
                     /locus_tag="ACHBV5_001951"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFM9967693.1"
                     /translation="MLQLEYKNEQSWDSFIDNVNLIELEERIQTTIGIKQINTHNIIT
                     IAREGYSQNYLPNTSENTYNSLQVSLVGVLLLFISMVNILWAKKSK"
     gene            5616..6383
                     /locus_tag="ACHBV5_001952"
     CDS             5616..6383
                     /locus_tag="ACHBV5_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HFM9967694.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            6385..7017
                     /locus_tag="ACHBV5_001953"
     CDS             6385..7017
                     /locus_tag="ACHBV5_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9967695.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(7963..8376)
                     /gene="ndk"
                     /locus_tag="ACHBV5_001954"
     CDS             complement(7963..8376)
                     /gene="ndk"
                     /locus_tag="ACHBV5_001954"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFM9967696.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
BASE COUNT         2954 a         1164 c         1493 g         2800 t
ORIGIN      
        1 ataatgtgag tcaacaaaag tctgtttttg taccatacta tcttgaaaaa tctactaaat
       61 tcaaattgag aggatgaatt aaaatgaata aaatatttat atatgcagga gtgcgaaatc
      121 ataactctaa gactttagag tatactaaga gactttcaag tatcatttct agtagaaata
      181 atgttgatat atctttcagg acacctttca attcagagct agaaatatct aattctgatt
      241 cagaagagtt gtttaagaaa ggaattgata ggcaaagtaa tgctgatgat ggaggtgtta
      301 taaaaaaaga gttattagag tctgatatta taattatctc ttctcctgta tatttacaaa
      361 acgtatctgt ggacacaaaa aactttattg aaaggattgg ggggtggagc catctttttc
      421 gattagctgg aaagtttgtt gtaacattag atgttgctga gagtaacggc tctgataatg
      481 tgtcagaata tcttagagat atattttcat atatgggagg acagatatta caccaagttt
      541 caattaccaa ttcactcaaa gatattgcag aggctcagtt gatggaggca acttataaaa
      601 ttgaagatgt acttgaaggg aaaattaagt acaaaacaac ggattatcaa gaaagagctt
      661 accagacatt aaaattaatt ttagaaaatt atgattccga acattttgag aagatgtatt
      721 gggagaaaaa acgccttttt gaagctaata gtttagagga atggtattat gttgaaaata
      781 ttaaataact ctgtcatata tttatgtttg attccgttat tgttcctatt attgataatt
      841 tttccaaatg attcattaat ctattatttt cgattgattt taatttcgtt aatatcaatt
      901 acattacatg aactaggtca ttttttagtg ggaagatgtt tatcttataa actagagatg
      961 cttgctactc cctttttctt ctatttcaga aaaaaaatat atttcaaatt tccagtgtta
     1021 ttagcattcg gttattgtca aatgagtaat agaaacatta ctaatgaaaa aaatagtgat
     1081 aggaatttgg tgttctactt ctttggggga ggtggagcta acctaattgt cgcaatatta
     1141 gcacttttgg gatttgtgcc gtacgcatca gaatttttta ttttgaatat aattcttttt
     1201 ctagttacgg tatgtttacc aattgatgga acagatggca atgctattag agagatagtt
     1261 ttgtattcaa aagattcaaa aacatatcag agattctttg cgaacagtct ctataataat
     1321 ccttatataa caatcgacga ttttgcaaaa ttaacctcta aagaaaaatc ttttttttca
     1381 aaatttgaaa aatgtttgat aaacctttac tttgaagtga aaggtgaagg gtcagcattt
     1441 acaattgcta atcatgaagt ttttgattca aatattcagg aaaatattat ccatgagtac
     1501 tataaattac tacataaatc ttctgattgg attattccac agaacttatc tttagaagaa
     1561 gttgttttta ccttgtcaaa ctatatttac tcgaaaaata ataaatattt agaaaagatt
     1621 aagtatctaa agaaattagt agattttaga caagaagaaa ttatcgactt tattttgaac
     1681 aaggaggaag tattgtgaaa attccaatga tatatcaaat ggaaaattca gaatgtggat
     1741 tagcatgctg tgccatgata ttgaactatt ttaaatatga gatttcttta aatgaactac
     1801 gtgaaatcta cccatcatcc agatctggat attctctcct atctataagt aaagttttag
     1861 gagattttaa tataagttct catgctttta aagcttcggt aagagattta aaaccgctca
     1921 gtttcccact catttgcttc tgggagagtt ctcattttat tattcttgaa aaaattagta
     1981 aaaacaagtt ttatatttta gatcctgcaa aaggcaggca gagaatgtca ataagtgaat
     2041 ttgaaaggca ttattcaaat atcattttaa catttaaaaa gttagatagc tttatgtctc
     2101 gtaaagataa taagaagtcg cctgttttaa agtatttttt taagtatagg aataagctag
     2161 ggattttatt ttttgtaaca gcattattgt atgtaataca atcattagta cctatagcta
     2221 atagatacat aattgacacg aatttcaagg acgattcgta ttcgtctaga atgttattta
     2281 ctatattatt tatatttact gtttcattct cactaatgta tttattaaga cagatatatg
     2341 ttgcatcctt aaaatatata atggataaag agattagcta tgattttatg aaacatttga
     2401 tatatttacc ttacagtttt tatgaaaaac gtactttagg ggatatactt tttagagcta
     2461 actctattgt ttatataaga gaaatactat caaataattt tatagcagct atacttgatt
     2521 tgttaatgat tgtggtttat gctgtggttt tatttagctt ttctaagtac atggtaatct
     2581 ttttaatatc actaagtcta gctctatcta ttgtaatgta tccaatcata aaaatctcaa
     2641 aaaatttaat tgataaaaat ataaaagaaa aggttaatgt tcaaaatatt acttccgaag
     2701 taatttctaa aaatagtgat attaagctaa ctggagaaga ggaattttgg attaacaaat
     2761 gggataattt taatacaaaa cagctcatca taggtcgaaa acttgatata catttatcaa
     2821 ttgttagtag tataacgaat gttttacaaa ttattctccc tgttttgacc cttattgtag
     2881 gtgtaaatat aaaaacattc gaacaattga cgttaggaca aattgtagca ataagtacag
     2941 tctcaccata ctttatttct cctataattt ctttaagtga taactatata caattaatgt
     3001 tattaaaggg atatttttta agaatagagg atgtgtttaa tactaaatcc gaattaattc
     3061 cagaaagagt cagtcaagat ataaaatttg ataaaaaaat agaattaaaa gatatttggt
     3121 ataaatatgg attatttgat gattatgttt tgaaaggaat aaatgttact attaaaaaag
     3181 gagaaactgt tgctattgtt ggagaatcag gttcaggtaa gagtacatta gctaaaattt
     3241 tattaggttt attagaacct aatattggtt caatagaagt tgatggagta gaaaaagaag
     3301 aaattggtca aacattgtat agaaagattt ttggagcagt gttacaaaat tcaaccctaa
     3361 gttatggtac cttaagagag aatttgacat ttggacactt tgtttcagat gaagaattaa
     3421 tgacaaatct aaattcaatt ggtcttagca atgtagttaa atctttacct cttggattag
     3481 agacaatcat cgctgaagaa ggtaataact tttctggagg gcagcagcaa atgatacttt
     3541 tagctcgttg tcttttgtcg aaaccttcgg tagttgtttt ggacgaagca acaagtagtt
     3601 tagataattt atctcaacaa attacaactt cttacttaag tgaaatcggt accactaaga
     3661 ttttaattgc ccatcgacta gatactatca agtctgcaga taagatctta gtaatgcata
     3721 atggtgaaat tgtagagatt gggacccata gagaacttct tgaactagga ggcatttata
     3781 agcaattgta ttcaaataat tagtttttga ttaaaagggt aaatttatga agattatgaa
     3841 aaaaaaatat tggactttag cgatattatt cttttgtttg ttcaataatt ctgttactgc
     3901 tcaagaaata cctaaaaatc ttgatggcaa tataactcac actcagacta gcgaaagttt
     3961 ttctgaatct gatgaaaaac aggttgacta ttctaataaa aatcaagaag aagtagacca
     4021 aaataaattt cgtattcaaa tcgataagac agaattattt gtaacaacag ataaacattt
     4081 agaaaaaaac tgttgtaaat tggaacttga accacaaata aataacgata ttgttaactc
     4141 tgaaagtaat aatttactag gcgaagataa tttagataat aaaattaagg aaaatgtttc
     4201 tcatctagat aatagaggag gaaatataga gcatgacaaa gataacttag aatcgtcgat
     4261 tgtaagaaaa tatgaatggg atatagataa agttactggt ggaggcgaaa gttataaatt
     4321 atattctaaa agtaattcta aagtttcaat tgctatttta gattcaggag tcgatttaca
     4381 aaatactgga ttactgaaaa atctttcaaa tcactcaaaa aactatgtcc ccaataaagg
     4441 atatttagga aaagaggagg gagaggaagg aataatatca gatattcaag atagattagg
     4501 tcatggtacg gctgttgtag ctcaaattgt aggggatgac aatattaatg gagtaaatcc
     4561 tcacgttaat attaacgtct atagaatatt tggtaagtcg tcagctagtc cagattggat
     4621 tgtaaaagca atttttgatg ctgtagatga tggcaatgat attatcaatc ttagtactgg
     4681 acaatattta atgattgatg gagaatatga ggacggaaca aatgattttg aaacattttt
     4741 gaagtataaa aaggctattg attacgcgaa tcaaaaagga gtaattatag tagctgcatt
     4801 agggaatgac tccctaaatg tatcaaatca gtcagattta ttgaaactta ttagttcacg
     4861 caaaaaagta agaaaaccag gattagtagt tgatgttcca agttatttct catctacaat
     4921 ttcggtcgga ggcatagatc gcttaggtaa tttatcagat tttagcaata aaggggattc
     4981 tgatgcaata tatgcgcctg caggctcaac attatctctt tcagaattag gacttaataa
     5041 ctttattaat gcagaaaaat ataaagaaga ttggattttt tcggcaacac taggaggata
     5101 tacgtatctt tatggaaact catttgctgc tcctaaagtt tctggtgcga ttgcaatgat
     5161 tattgataaa tacaaattaa aagatcaacc ctataattat atgtttgtaa aaaaattctg
     5221 gaagaaacat taccagtaaa aaatggtata aaagtgttaa atataccaaa cgtattgaga
     5281 tatgatttga atatgttaca attagaatat aaaaatgaac aaagttggga tagtttcata
     5341 gataatgtta atttaattga gttggaagag agaattcaaa ctactattgg aattaaacaa
     5401 ataaacacac acaatattat tactattgcc cgagaagggt actctcaaaa ttatttacct
     5461 aacacttcag aaaatacata taattcatta caagtcagtt tagttggagt attactactt
     5521 tttataagta tggtaaatat tttatgggct aaaaaaagta aatgaaaata aaatttggag
     5581 ccctctgaaa aagtaagtcc tacagttcaa ctaaaatgag tcaaaagatg aatcaccttg
     5641 atgtagggga gtttgtctta ttgctgcctg aacacctccg ttcagaggaa gaacattata
     5701 aatctgtttt tgaagacgac ttaaccagtc gcatatctag tcaagatgaa cgacagcaaa
     5761 tgactgctac ggtaggttat ttagaatcag gtcaggatcg ttttgtgtat aatacgaccc
     5821 ctatttctta ccagcagttt ttgaaagatc caatcatcat tgttataaca ccccaatcaa
     5881 ctggtccaca gtccattttg ttttggatag acgcagtaca gaactacgtt ctctttaatc
     5941 aattgtctga tgcccaggag cttatccaga gacaaggcat tgaaaattgg gtctcagaaa
     6001 tgcaaacagg ttaccacaac tacatcacat tattggataa tatccagagg gaacgttggg
     6061 taatgctagc aggagctgtg cttgggattg caacttcaat cttgttgttt aacactatga
     6121 ataggctcta ctttgaagaa tttagacgtg ccatttttat caaacgcatt gcaggtctca
     6181 ggttcttaga aatccatcgc acttatctct ttgctcaact gggtgtgttt ttactgggat
     6241 ttgttgcgag tgtatttctt caggtagaga taggagttgc tttcttagtc ttgttactct
     6301 ttactggtct atctctttta cagttacatg tccaaatgca gaaagaaaac aagatgtcca
     6361 tgcttgtttt gaagggaggt taatatgatt gaacttaaac aggtgagtaa atcttttgga
     6421 gaacgagagt tattttcgaa tctttcaatg acatttgagg ctggaaaagt ctatgcctta
     6481 attggttcaa gtggtagcgg aaaaacaacc ttgatgaaca tgattgggaa attagaacct
     6541 tatgatggga cgatttttta ccgaggtaaa gacttggcca attataaatc aagtgatttt
     6601 ttccgtcacg aattgggcta cctcttccag aactttggct taattgaaaa ccaaagtatt
     6661 gaagaaaacc ttaagctagg tctcattggt caaaagttga gtcggtcgga acagcggttg
     6721 aggcagaagc aggctttaga acaggtcggc ctggtttatc ttgacctaga taagcgcatc
     6781 tttgagttat cgggcggaga atcgcaacgg gttgccttgg caaaaattat cttaaagaat
     6841 ccacccttta ttctggcaga tgagccaaca gcttcaatag acccagcaac ctctcagttg
     6901 attatggaga ttttgctatc tcttcgagat gataataggc taatcattat cgcaacacat
     6961 aatccggcaa tttgggagat ggctgatgaa gtgttcacga tggatcatct gaaataaaaa
     7021 tccttgtttt taattgcacg atgagttact gaaatattat catgaatcaa gaattggagt
     7081 taatttagaa ttgtacttaa tttagaattg tactttatta atattgaggt aactttttct
     7141 tgataaagga agaaataatg gagaggaagt tagaatgaaa aaattcgaca attatattat
     7201 tgagaagcct tgcgattcta attcagataa actgcaaaaa atcttaataa ttgaaagttt
     7261 ggtagatgat attttgcaat tttctctcag aatcaataat agtgtaggag agattttcct
     7321 cctacaaccg ttttaaaaga aaactatctt tattccatgt tattttgagg aagatattgt
     7381 gaaagtcaaa gatgatgata aagttgagtg gaatttgtta gaatttcaaa aatttagagc
     7441 atttttggct tagtaatctg tgttgaaggc tcaaaaccta tggtaaaaaa gtagctttga
     7501 aaacgtattg cctccaaaga tttagttaaa taatgattta acacaaaaag aaattattga
     7561 agttctggaa agatgttgtt tcagtattga gaaaaggtgg gaaaaacttg cgattttcac
     7621 agagaaagga agaaaaagta tagaaatata gtcaattgaa acaagaacag gataaaagaa
     7681 ccttttgtgc catatttttc tcctttcgct ttacaattgg attgaacacc tttattgtat
     7741 cgcgtatgga gtttttttgg tataaccttc gacgcacacc cgcatagcgg gtgttttttt
     7801 tgtctcgcac ctaacggagc gagacaaact aatagtcact taatcaaaaa acgcaccata
     7861 tcaaaaacta aaaagtttga tatcatgcgt catgtcttaa actaattgac tatactttct
     7921 attcaaatga gcttttaacc aattgattga gccaatccac tcttaaaacc aaagagcaat
     7981 ttctcgctta gctgactctt ctgaatctga accatgtaca acattttgga taatctcatt
     8041 ttctccagca gcttttgcaa aatcacctcg aatagtgcct ggtaaagctt cttctggacg
     8101 agttgcaccc atcatggtcc gccaagtttc gattactttg ggaccagaaa tgacacccac
     8161 aagaactgga cctgaagtca tgaattcacg aatcggtggg taaaaactct gaccaaccaa
     8221 gtcctgatag tgctggtcaa tcaactcttc tgaaacctgt gaacgaaact ccaatttttc
     8281 gattgtaaat ccacgttgtt cgatgcgctt taacacttca cccactagcc ctctttttac
     8341 accatctggt ttgatgataa agaatgtttg ttccataccc gtctcctttg tcagcttctt
     8401 tcttttattt t
//
LOCUS       DAYYYC010000072         8086 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.072, whole genome shotgun sequence.
ACCESSION   DAYYYC010000072 DAYYYC010000000
VERSION     DAYYYC010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8086
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.072"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..1579
                     /locus_tag="ACHBV5_001955"
     CDS             <1..1579
                     /locus_tag="ACHBV5_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFM9967697.1"
                     /translation="LLTIFIVAGQLLLIYAATINALVLNELIAMNLERFLKLSIYQMI
                     VWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHSKSSGTYLSWLNND
                     VQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLMIMLLVPKIFASKM
                     REVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAGILLKMVIQRKTTV
                     ETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTGVIFTALGELGGQL
                     SSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNICYKYGDKEILKNLN
                     FCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIKKTSYLNMVSNVLY
                     VDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNILDYYVGDDGRLLS
                     GGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDREDLTVIIVTHAPHP
                     ELKQYFTKIYQFPKDFI"
     gene            1840..2268
                     /locus_tag="ACHBV5_001956"
     CDS             1840..2268
                     /locus_tag="ACHBV5_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967698.1"
                     /translation="MSEIVEMSKKISNLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            2280..3029
                     /locus_tag="ACHBV5_001957"
     CDS             2280..3029
                     /locus_tag="ACHBV5_001957"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HFM9967699.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            3042..4214
                     /locus_tag="ACHBV5_001958"
     CDS             3042..4214
                     /locus_tag="ACHBV5_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HFM9967700.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIAIPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     FFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFEFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            4609..5472
                     /locus_tag="ACHBV5_001959"
     CDS             4609..5472
                     /locus_tag="ACHBV5_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HFM9967701.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFLYIPIFE
                     AELESMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFTQSLQVLENPQLTSLFE
                     LRLQQYKKLID"
     gene            5758..5955
                     /locus_tag="ACHBV5_001960"
     CDS             5758..5955
                     /locus_tag="ACHBV5_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HFM9967702.1"
                     /translation="MLNLQFAETMELTEAELETGYGGEFGNNAVIPAGAWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            6023..6688
                     /locus_tag="ACHBV5_001961"
     CDS             6023..6688
                     /locus_tag="ACHBV5_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HFM9967703.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            6760..7986
                     /locus_tag="ACHBV5_001962"
     CDS             6760..7986
                     /locus_tag="ACHBV5_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFM9967704.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLT
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         2600 a         1176 c         1509 g         2801 t
ORIGIN      
        1 tttattaacg atatttattg ttgctggtca attattgcta atttatgcag caactattaa
       61 tgctctggtg ttgaatgaat taattgcgat gaatttagag cggtttttga aattgtcaat
      121 ctaccaaatg attgtctggt gtgggataat attccttgac tgggtagtga aaaattatca
      181 ggttgaagtg atccaagagt ttaatctaga gattcgaaat agagttgcca cagacatctc
      241 taactctacc tatcaagaat ttcatagtaa atcatcagga acatatcttt cgtggctaaa
      301 taatgatgtt cagactttaa atgatcaggc ttttaaacaa ctttttttag taataaaagg
      361 aatttctggt actatatttg cagttgtgac tcttaatcac tatcattggt cattgactgt
      421 agccaccttg ttttcattaa tgattatgct acttgtacca aaaatctttg catcgaaaat
      481 gcgagaagtt agtctaaatt taactagcca aaatgaagct tttttaaaat ctagtgagac
      541 tatattgaat ggatttgatg tgttagcgtc cttgaatctt ttatatgtat tgcctaagaa
      601 aattaaagaa gcaggaattt tattaaagat ggttatacaa agaaagacaa ctgtagaaac
      661 gttagcaggc gctattagct tctttctcaa tatttttttt cagatatctc tcgttttttt
      721 aacaggctat cttgcaataa aaggaatagt gaaaattggt actattgaag caataggagc
      781 actaacaggt gttattttta cagcgctagg tgaattagga ggtcaattat cctctattat
      841 tggtacgaag cctatttttt taaaattgta ttcaattaat ccaattgagt caaataaaat
      901 gaatgatatc gaaccaaatg aggtgaatag agattttccg ttatatgaag caaaaaatat
      961 ttgctataag tatggagata aagaaatatt aaaaaactta aatttttgtt ttcaacgtaa
     1021 tgaaaagtat ttaattttag gtgaaagtgg aagcgggaaa tctacattat taaaattatt
     1081 gaatggcttt ttgagagatt atagtggaga attgcgattc tgcggggatg atataaaaaa
     1141 aacctcctat ttaaatatgg tttcgaatgt tctatatgta gatcaaaaag cttatttgtt
     1201 tgaaggtacg attagagata atattttatt ggaagaaaat tatactgatg aagaaatact
     1261 acagtcttta gaacaagttg gtttgagtgt aaaagatttt cctaataaca ttttagatta
     1321 ttatgttggt gatgatggga gattactgtc aggagggcag aaacaaaaaa ttactttagc
     1381 tagaggccta attagaaata agaaaatagt attaattgac gagggaactt ctgctatcga
     1441 taggagaact tcgttagcga ttgaacgtaa gatattagat agagaggatt tgactgtcat
     1501 tattgttacc catgctccgc atccggaact taaacaatat tttactaaga tatatcaatt
     1561 tccaaaggat tttatttaag aatatagggg agggaaacat gagattctat tgtgaagctt
     1621 atgaggtaat tactgaagag aaaaaagtat cattttttta tgtagatgag aaacccttaa
     1681 ggtatctgtt atttgactat atatttctac tagttctagc taaaaaaaaa tatcccaatc
     1741 ttatgaactg caccccaaaa gttagattta ttctgtctaa cttttggggt gcagttcatt
     1801 ttgcatagtt ttggcattca tcctagatat ccatataaaa tgtctgagat tgttgaaatg
     1861 tctaaaaaaa tatcaaatct aaacgataaa aaagaatttc acaaaaagaa ctgtgagttg
     1921 aggtttcaag atagtgttct tgataacata aatagtgtcc cgggtacaac tcatttattt
     1981 agttgtttaa atattcaaac attagtaaaa attattttat atatttttcg atacaacagt
     2041 tgtatgaaaa tatttaattt tagagataaa gagcttatct tttttaataa gattgtaaat
     2101 gggctgatac aaaatattga ggagaattta gaggatgata ttgaaaggat attgaaatat
     2161 ttatatatat gtttatttaa cgaaatattc attattaaga ataaggtgaa tttttttgat
     2221 gatgtggaat ttaatcagac acttagtgag tttttagata aattgtagag ggaatggtta
     2281 tgagtaacaa tactaagtat atctttttat ctccacattt agatgacgca attttttcct
     2341 gtggtgatta tatttcaaaa ttaacttcag aaggagaaat tgtacttgtt attactatat
     2401 tttctggtta ccctttgagc caacagctac agccctctgc taagcaattt cataagttgt
     2461 gtaaccttgg gaaatatccg attgaagaaa ggaagaaaga agacaggtta gcttgtgaac
     2521 gtctacaatg tgattttaga cacttatcgt actatgaatg tctctatagg aaagatagaa
     2581 atggcaattt tctataccgt catatctata gtgaattaaa aaatgaggac acattaaaga
     2641 atgatatcat aaaagagctg ttaatgcatt tagacgataa atgtgtcgta tattgtccgc
     2701 tttcacttgg tgaccatgtt gatcatgttt ttgtgaatag tattggaagg gcgcttgaat
     2761 ttatgcgtta taaagtaata tattatgagg acttcccata tgtaagtgat agtagtatgg
     2821 ttagttatat gggaaaaact aaagaattaa aaatgtatca agaggaactt gatgaaaaac
     2881 attatattga tagaatatca tcaatattgt gctataaatc tcagattttg ataatctgga
     2941 aatcagttga aaaactttta aacaatatta aagagttgta tttaaggaat ggggcagctt
     3001 attctattag attttggatt aagaaataag gaagtagttt tatgaatata gcagtaattg
     3061 gtttggggca tgttgggctg gcctacgcgt tactatttgc atctaaatat aaagttgttg
     3121 catatgatat agattctgta aaaataaata atttaaaaaa gggcattctt ccatctaaaa
     3181 atgaagagct tatgaagttt ttttgcgaga ataacttaaa tattactttt tttgatacat
     3241 tttctgaaat taaaaataat attgattatt atattattgc gattccgaca gattatgatg
     3301 agaaaattgg tagttttaat acatatgaaa tcgaacaaac ggtatcgaag attctgaggg
     3361 taaaacctaa tggaaagatt attttaaagt caacagttcc gatcggcttt tcaaacaaat
     3421 taaaaaggct gtttgataca aaaaatatca tttttgtccc tgaatttttg agagaaggtt
     3481 gttctatata tgataattta tatccaagtc gcatagttgt tggagatgag acagttgaag
     3541 gaagaaaaat tgcagagttg ttcctttcga ttagtactca tagtactgcc aatattaaaa
     3601 atgttatgtt agtttctcct actgaagcag aagcaattaa gcttttttct aacacattct
     3661 tagctctccg tgttgctttt tttaatgaac tagatttttt tgctgagagg agaagtttaa
     3721 atgctgaagt tgtaataaaa ggtgtttgtt tagatccaag aattggaaat ttttataata
     3781 atccttcttt tgaatttgga ggatattgtc ttcccaaaga tactaaacaa ttaaaaaaag
     3841 aatttataga aataaatgcc ccagtgatag aagcgattga tatttcaaac acaaatagaa
     3901 aacagttcat agttaaacaa atattggaac gaaagccaaa gatagtagga atatataaat
     3961 tggggatgaa atataattca gataattaca aagagtcagc tattttaagt ataattaatg
     4021 aactattgat tgtcggtata aaaattttag tatatgaacc aaatttaaac gttagtatag
     4081 ataacgtaat ttttgaaaag aattttgaac tatttacaaa acaaagtgat ctaattgttg
     4141 caaatagatg ggataggggc cttgaagctt ataaagataa agtttacaca agggggatct
     4201 ggataagaga ttaactattg atattaaaaa ggcaataatt tataaaattt gtacaaaaaa
     4261 atgttaaatt ttcacatttt catagtatac tgtttaatag aaagtaggtt ctttgtaacc
     4321 gctccattat aaaatccttt cactcttccg gtatgctatt aggaaaaaca taattggagg
     4381 atattttgag ctcacacctc atcgttccag tggctgttcc ccaagctcgt gtactgccca
     4441 aaaaagttag acattctatt tagaacgagg attgagttct gtattgtaca aggctcggtc
     4501 cttttagagt cagcttaagg ctggcttttt caatcaccaa agtgtcagaa tgttttgaca
     4561 aatgaacaca aataatgata taatatgcaa aagctaggag gtggtaggat gattgaaaaa
     4621 atggaactgg gggaatttta caaggaatta cgtttggcga gaaagctcaa gcagtcagat
     4681 gtggcttgtg acgggctaac agcttctcag ttgtccaagt ttgagctagg gcagtccatg
     4741 ttgtctgctg ataagctcat attagccatc caagggatca atgtgacctt tgatgagttt
     4801 gggcacaagc tcaacaacta tcaagaatct ccacatatgc agattggtag aaaggttgtg
     4861 gatcgctttg ctcatcaaga tatagctggc ttagagcaac tgttggagga agtcgagcaa
     4921 gaacagatgg cagagactta tcgtcgtttg aatgctattg taatcaaaga tgccatccac
     4981 tcactagata aaagctaccc actagcagag gaggatagcg agtttttgac cacctatctc
     5041 tatgctatcg agtcttggac ctggtttgaa ctctatctct tttgcaatac tctgcccttc
     5101 ttgagcaatc aagatctgat ctttttatca acctccttac tcgaaaaatc caaagaattt
     5161 aaagagttag tacacaatcg attgtatatg aagcaaggac tcttaaatat cttatcagaa
     5221 ctcatggagc gaaaactttt cttatacatc ccaatcttcg aagccgagtt ggagagcatg
     5281 ttgcgtccgt acgatgtttt tgaaaaagta tcgtggcaat ttttaaagaa gatgagtgtc
     5341 tttcttcaaa caaagggaag caatcaaaaa gagattgaac gctttaccca atctctgcag
     5401 gtattagaaa atccacaatt aacatccctt tttgaattgc gtttgcagca atacaaaaag
     5461 cttatcgatt agttagaaat ggcaaaataa taataatctc agcaacgatc gtcaataatg
     5521 ttaaaacttg tttcttcata ttacttccct cctcattagt aataacttta ttataccagg
     5581 gaaataatca aatctaccaa aatcgcaaat ctgaaatttc tataagaaaa aatatcaaat
     5641 atgcgatttt ctaaaataag ccaatttccg tgttatactg tccttgtaaa acatttgaag
     5701 caaatcctag gtcgcagaag tggtttacaa atgaagataa ttgaaggagt gtaaaagatg
     5761 ttaaatttac aatttgcaga aacaatggaa ttgacagaag ctgagttgga gacaggttat
     5821 ggaggggaat ttgggaataa tgctgttatc ccagccggtg cttggggagg tttaggaacg
     5881 tcttggtcaa tcactaattt ctggaagaaa tattttaacc atgattcttc cactgttaat
     5941 cgtcgccatt attgatattc agagtccttg cctttttctt gggtagggac tgtctttatt
     6001 tcatagtata ggagaaaata gaatgaaaaa gataatctca caccgctact ttattatagt
     6061 ttttctacta gttattgctg accagaagtt cagtgtttta gttttacgca gcgaccttgt
     6121 tgctgggcta tctgactttg cctattatct gtcggatatg atgttgaatt ttcttgtggt
     6181 tttatttgct cttattgcta tgatttggtc ggggaaatgg cagaaaatca atagtagaaa
     6241 gtttaaagga tcctatcttt tctattcctt cctagctctg cttgcttttg ttgcttggaa
     6301 ttttgtcacc ttttttcttt tcccacctac tcgaaatgaa atttcttatc aacatgctgc
     6361 tcctactttt acaggagcta cggcattttt gatgtatttt ttttatcctg tgattgcagg
     6421 tcccattttt gaagacatga tttatcgtgg attagtgatg actgctctgg aaaaaggaaa
     6481 gaaatggggg ctagatgtac ttggttccgc tgttttattt ggggtctcgc acattagtaa
     6541 tcacggttgg gtcttgacag actttgtctt ctatatgggt ggaggtctta tatttgcagt
     6601 cttatttaga atgacaaagt caatttattg gcctattgga ctgcatatag tctacaatgg
     6661 cattggtcag cttttgatgt tactgtaatt ttggttgtta gtagtatcgc ggtctatcct
     6721 tggggaaaga ttcccatttg aacttaagaa ggagttgtga tgaaagtatt tcttcaaaat
     6781 agagatttta ggcaattaac tatcaaccag tggatttcaa cgcttgggga tacgattttt
     6841 tatctggcct ttctgaatta tgtggcagat gcgtcttttg cacctttgac gattttactc
     6901 attacgattt cagaaaccct tccccaaatt ttacaaatct ttctgggagt tttggcagat
     6961 tttcaacatc atcgtgtctt gaaatacaca gtcattagtt ttgcaaaatt tttgctttac
     7021 tctatcgttt ctttatcact ttcagggcag tctttctcct tgttgctagt agcatttatt
     7081 tgtctgctta acctcttgtc tgacacattg agttactttt caggagccat gctcactccg
     7141 attttcatta gaattattgg gcaagaccat ctggcagaag ctattggctt taaacagtca
     7201 actgttagtt tagtgaaaac aatcagtaat atcctaggag gagtcttact aggcattcta
     7261 tccatccagt ttatttcctt actgaacgct cttacctttt taatcgcatt tttaggtatc
     7321 ctcttcataa aaactgacct cttgaaagta gaaaaaacga ttagctatca agaaggactc
     7381 tctgtaaaat ccttttgcca gcatttgctc caatcatcaa aattgatatg gaatatgaat
     7441 aaggtgctct tggttttgtt tattatctct actagtcaag cagtgataaa tgttacggtt
     7501 cctatttcca ctctattttt aaggaaccag ccctttttga atttacaaac aggtcaatct
     7561 cttgccttgc tatccacttt tgaactgtca gccctgattg tcggaagcct tgtaagtggc
     7621 tatctgcaac ataccatttc cataaaaaca gctctctatg cctcacttgt catccagttg
     7681 cttcttctag taggatttgc cacagttcgt tttgactgga ttctcatctt tagtaccttg
     7741 gatgcctttt tcgcaggtgt tctctctcct agattgcaag aactcgtttt taaacaaata
     7801 cctgaggagt caatgggagc agttcaatcc tctatcggtg ccattacggt tgttttacct
     7861 agcttattta caatagcttt ggtaaccatt gctactagct ttggaactct ggcagttagc
     7921 tttgttttat tgctatttct tctagttgcc tttgttatgc ttctgaatat tcgtgaaagt
     7981 atttagtgga gaatttctat aatatatgtt tgagactgga ttgccagtct ttttatgatg
     8041 gtcaaaatca acagactttt tctcttttct gaatgtgtta tagtag
//
LOCUS       DAYYYC010000073         7720 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.073, whole genome shotgun sequence.
ACCESSION   DAYYYC010000073 DAYYYC010000000
VERSION     DAYYYC010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7720
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.073"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(1..846)
                     /locus_tag="ACHBV5_001963"
     CDS             complement(1..846)
                     /locus_tag="ACHBV5_001963"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFM9967705.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKACAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            1102..2129
                     /locus_tag="ACHBV5_001964"
                     /pseudo
     CDS             1102..2129
                     /locus_tag="ACHBV5_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(2430..4319)
                     /locus_tag="ACHBV5_001965"
     CDS             complement(2430..4319)
                     /locus_tag="ACHBV5_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HFM9967706.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGTEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKEQSKQLLTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFERDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLLGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            4457..6022
                     /locus_tag="ACHBV5_001966"
     CDS             4457..6022
                     /locus_tag="ACHBV5_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFM9967707.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYANAKSLDDFNGAKITSQQGVYLYD
                     LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGF
                     KTGEEDTAIAIGLRKDDTRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTITGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWILNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            6022..6762
                     /locus_tag="ACHBV5_001967"
     CDS             6022..6762
                     /locus_tag="ACHBV5_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFM9967708.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(6871..7086)
                     /locus_tag="ACHBV5_001968"
     CDS             complement(6871..7086)
                     /locus_tag="ACHBV5_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967709.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
BASE COUNT         2444 a         1718 c         1370 g         2188 t
ORIGIN      
        1 ttatacaaat aaacggacaa aactgtaaag tagcaaaaca ctaccaagca cgatacggta
       61 tttaccaaaa agggtgaagt cgtgtttttt cacatagctg gtcaagaagc gaatagccac
      121 catgctgacc gcaaaagcta ctcccatcgc gaccaagagc aaaaacaatt gcccaaagct
      181 caagagttct ccggctttca caaatttgaa aatctttaag gcactagctc caaacataac
      241 gggaatccca agatagaagg taaattctgt cacaactgaa cgactggttc catttaacaa
      301 accaccgaca atcgttgcac ctgaacggct agtccctggt aaaagagcaa gaacttggaa
      361 gagtccgata tagaaagcgg tcgtataagg aagcttgtcc aactctgtta cacttggctc
      421 gatagcacac gctttattgc gcttttccaa atagatgaag gcaaccccgt agataatcaa
      481 catgagagca actgaaacca tgttatggaa gtgggtatca aaccaatcat caaatttaaa
      541 gacaccaagt aaaggtaaag tagcaatcaa gaccttcaac catagtctcc aagtcttacg
      601 aacttcctgt ttgtccttag tcggtttaaa aggattgagc ttgttaaaat aaatcaccat
      661 aactgctaaa atagcaccaa gctgaatcac gacattaaac atggacataa aggcttcatt
      721 ttgattttgg tattggataa actcctctgc taaaatcaag tgacctgtac tggaaatcgg
      781 caaccattcc gtaattcctt caacaatccc gaagaagata gattttaaaa tttcaataag
      841 atacatatat ttctccttat attatattta acgcagttag ctactgccaa agcccaagtg
      901 gtatacttgg aataagccac tgtggattag ttcatttcct ccaatcgctt gacgatttcc
      961 gaaaggatct aaccacagct ttttgtttca attggtaatg agtttgataa cgcatagacg
     1021 ttttatctcg tctaaggtaa caaggcaaaa agttcgtgga taaccaagta gacttgaaat
     1081 actatatctg gaggtactcc catgctttat gtgggcattg atgtcgctaa aaataaacac
     1141 gatgttacag ccttgaatgt tcgaggaaaa ctgttcttaa accactcact ttttcaaata
     1201 ataaagctgg ttttgaacta ttagatctgt ctcttcgaca gctcaaccaa gactgtctca
     1261 tcgctcttga agataccgga cattatgcct ttaatctact gaacttcctg catgaacaag
     1321 gatataaagt ttacacctac actcctttgc tcatcaagga atttgccaaa tcattatcac
     1381 ttcgcaagac taaaacggat aagaaagacg ctcatggcat cgctcttaaa cttctttctg
     1441 accccaatcg tgaacaattt caacacgata atcggcaagt agaactaaaa atactggcta
     1501 gacatattca tcgtctcaag aaaaaacagt ctgattggaa agtacaatac actcgttgtc
     1561 ttgatatcat ctttcctgag ttggataaaa tcgttggaaa gcattcagaa tatacctacc
     1621 aactcttgac atgctaccct aatcctcaga aaaggcttga ggcaggattt gataagctga
     1681 tagaaattaa gcgattgacc gcttctaaaa ttcaggatat cctctcagtc gcacctcgtt
     1741 ctatcggaac aacatctcct gctcgtgaat tcgaaatcat cgaaaacatc aaacattaca
     1801 agaggctcat tgacaaggcg gaaaaatgtg tcaatgactt gatggctgag ttcaactcgg
     1861 tcatcacgac ggttactggg attgggaatc gtttaggggc ggtcatttta gccgagattc
     1921 aaaatattca tgcctttgat aatcctgctc aattacaagc tttcgctgga ctggattctt
     1981 ctatttatca gtcaggtcag attgatttag ctggaagaat ggtcaaacgg ggttctcctc
     2041 atctgcggtg ggcactcata caagctgcca aagcatgcgc tcgcttttca cctgctttta
     2101 aggcctatct taagactaag ttagaataag aaaaacatta caatgtagcc atcatccacc
     2161 ttgcaaaaaa acttatccga accctgtttt atatcctaaa aaagagctgc catttgacga
     2221 acaaaaagtg atgtaatttc tgaaatcaac acaggattac ctttgaaaaa atggactttt
     2281 tcaagggctt tttgccgtgc tctaaaatca tcgccaaatc atcaaattga aataagaaat
     2341 agtttagata aaattattga cttttcttat agtttgtctt tcttctatct tccattatat
     2401 catacttttt cagtctatgg tagctctctt taaaaggctc cgatactgcc gccacctccg
     2461 cctccagaga agccaccgcc agaacttcca cttccagaag atacggagta ggtacttgct
     2521 gtatttgcga cactagcata atggctcatt tgcgcgcttg aatgataaaa catactgtgc
     2581 cagccataag ctacatagag attgatatct ggattttcaa cttgaatctg atgaaccttc
     2641 atcaaatgac taaccttgtc cgcatagcca agtaaggttg catagaccaa gagacgattc
     2701 caaacaacaa tactttccaa ttcagcctta tccagtcgtg caatctcacg taacatattt
     2761 tcaaaactgg tccagagata gtagacctca gctcccgctt catttagaac accatcacga
     2821 ttatctagtc gaagcttcca ataatagaaa acagacaaaa ctaaccctag aaaaccaagt
     2881 attggcaaag ggaggtaaag atagccatga acgtctaaac tgtacaagaa caaaccaaat
     2941 ccgataaata ggggcaggat agtcaaggca cccataccca cttgcaaggc cttttcccca
     3001 ccagttaaag gacgataata atctgggagc ccccagaagg aaactcgttt tctcactcct
     3061 tcttgcatct ggttcaatac ctcttcaaaa gaagatttga gttgaagccc tcttgcttga
     3121 atccgttttt catcagaaac tttggctcta cgataaagac tatcagatac cttgtaatcc
     3181 gcaaacaaat tggaaagagt ttcttctttt ttacctgaaa aggctagatt tagacagtct
     3241 ctctcaaagc ttgacaaacc atcttctttt actagcctca aaccaactgc atctccttct
     3301 gaaatgatag agacattccc acggtctatc acatctagca aggtagcttg aataagttga
     3361 tcaaaggtga attttccagc tcccttgacc aagggactca cttcctccaa ggaggtcgag
     3421 tagactgctt ctgataaaac cataggctct aattccattg gtggttcata gagacgatga
     3481 tttttggcat atttgactga aggagtggtc tttcttctat aaataaaata gaagcagaca
     3541 ctcaataaca aggagatgga aaggatcgaa gggaggaccc aagtaagtag ttgtttactt
     3601 tgctcttttt ctctaacaat cgagtcttct atcttattaa actcttctaa tcgattccct
     3661 ttcaatccct gatccctagc gctagcaaaa tcggtccgag gccaataggc atgcaactca
     3721 actccacgct tagccggaag attgtctaaa cggatagtat aatcaaggtt actcttttca
     3781 atcgttccct ctctaaaaag tttccctgta tggaaaaaga gtttttcagt ccccttgtct
     3841 ccccttacat gaaattcaaa cttttcaata gactctgaac tatctgtcag aggttgccaa
     3901 tttaattcag cgatatcatc ataaaggaaa agtaaatttt ttaagttcca gacgaggtca
     3961 acttcaacta tgtcgccctc ctgacctgga ttatagactc tcacagtata accatccgct
     4021 tcttctgtta cttcgctagt cacatctgct agttctgcac cgtttttcgc ggcctgaatc
     4081 tttggatgag ggtcaatgtc aaacccgcta ggcatcttac cagcacgtcc aagtcccacg
     4141 atttggccct taaagtcctc ctcaaactgg taaactatct tctgtctaaa ctctgccgta
     4201 ttatctgcat gaatatacaa atccccttga taagagttta tcttgaaatc aatggcaaaa
     4261 acagagagtg gaagaaggca aaacaagcct aacaccagta agaaaaaagt ttttttcatc
     4321 aactaagccc cctttttatc tttcttatca ttatagcatt ttttcgtaag taaaggctta
     4381 cttatgttga aaaattacgc atttttcgat aaaataggag acagttattt tttaatagat
     4441 cagaatagga gaaatcatga gaaaaatata cttatctatt ttcacaagtc tcttgctgat
     4501 gctaggactt gtcaatgttg ctcaagccga tgaatattta cgcatcggga tggaagcagc
     4561 atatgctccc tttaactgga cccaggatga tgatagcaac ggagctgtca aaatcgatgg
     4621 gaccaatcag tatgccaacg gatacgatgt tcaaatcgcc aagaaaatcg ctaaggactt
     4681 aggtaaagaa cctttggttg ttaaaaccaa gtgggaaggt ctagtccctg cccttacttc
     4741 tggtaagatt gacatgatta tcgcaggtat gagtccaact gcagaacgca aacaagaaat
     4801 tgccttttcg agcagttact acactagcga accagttcta ctggtcaaaa aagattctgc
     4861 ctatgcaaat gctaaatctt tggatgactt taatggtgcg aaaatcactt ctcaacaagg
     4921 tgtctacctt tatgacttga ttgcacaaat cacaggtgct aaaaaagaaa cagccatggg
     4981 agacttcgct caaatgcgcc aagctcttga ggctggtgtc atcgacgcct atgtttctga
     5041 acgcccagaa gctctgactg ccgaagccgc taactctaag ttcaagatgg tccaagtaga
     5101 accaggtttc aaaactgggg aagaagatac agctatcgcc attggacttc gtaaagatga
     5161 cactcgtatt agccaaatca atgccagcat tgaaaccatt tcaaaggacg accaagttgc
     5221 cctgatggat cgtatgatca aggaacaacc tgccgaagct acaacaactg aagagactag
     5281 cagtagtttc tttagccaag ttgctaaaat tctttctgaa aactggcaac aactcttgcg
     5341 tggtgctggt atcactcttt taatctctat cgtcggaacc atcacaggtc tcattattgg
     5401 acttgccatt ggtgttttcc gtactgctcc tctctctgaa aacaaagcca tttacggcct
     5461 acaaaaacta gtcggctgga ttctcaacgt ctacattgaa attttccgtg gtacgccaat
     5521 gattgttcaa tcgatggtta tctactatgg aactgcccaa gctttcggga tcaaccttga
     5581 ccgtacactg gctgctatct tcatcgtttc aatcaatacc ggtgcctaca tgactgaaat
     5641 cgtccgtggt ggtatcctag cagttgacaa gggacaattt gaagctgcga ctgctcttgg
     5701 tatgacccat aaccagacca tgcgtaagat tgtcctacct caggtagtcc gtaacatcct
     5761 acctgcaact ggtaatgaat ttgtcatcaa tatcaaagat acatctgtat tgaacgttat
     5821 ctctgttgtc gaactttatt tctcaggaaa taccgtggca acacaaacct atcaatactt
     5881 ccagacattt acaatcatcg ccgtgattta ctttgtcctc accttcaccg taacacgtat
     5941 cctacgattt atcgagcgcc gaatggacat ggatacctat actacaggtg ctaaccaaat
     6001 gcaaacggag gatttgaaat aatgacacaa gcaatccttg aaattaaaca cctcaaaaaa
     6061 tcctatggac aaaacgaagt gctaaaagac atttcactca ctgtccacaa gggagaggtc
     6121 atctctatca tcggaagctc tggaagcgga aaatcgacct tcctacgctc cattaaccta
     6181 cttgaaacac caactgatgg acaaatcctt tatcatggac aaaacgtcct cgaaaaaggc
     6241 tatgacctca cgcaataccg tgaaaagttg gggatggttt tccaatcctt taacctcttt
     6301 gaaaatctca atgttcttga aaacacaatc gtcgctcaga caactgtcct aaaacgcgaa
     6361 cgcacagaag ctgaaaagat tgccaaagaa aacctggaaa aggtcggcat gggagaacgc
     6421 tactggcaag ccaaaccaaa acaactctca ggtggtcaaa aacaacgtgt ggccatcgct
     6481 cgtgccctct ccatgaatcc ggacgctatt ctctttgatg aaccaacatc agctctcgat
     6541 ccagaaatgg ttggagaagt cctcaaaatc atgcaggacc tggctcagga aggcttgacc
     6601 atgattgtcg taacccatga aatggaattt gcccgtgatg tctctcaccg tgttatcttt
     6661 atggataagg gcgtgatcgc tgaagaaggt aaaccagaag acctcttcac caatcctaaa
     6721 gaagaccgaa caaaagagtt ccttcaacgc tatctcaaat aaaaagaaaa ggctgcatca
     6781 accgtgcagt ctttttgctg tcctcaaaat gaaaaggcag attctctatc tctactactt
     6841 gaaggtcaag aatccgccgt tatccaaaga ttaatcttca aatttttcat aatttttttc
     6901 atagaaatca attaggccta gggctgtttc aaatgaaata ttttttactt ttgcacgacc
     6961 ctgcgccaga gcaatgatag acatttcacg cgcattcgtt tctttagaga tacggtagcc
     7021 tgtgattttc ttatcacgaa cccagccaac aactgattct actttttcaa agtttgactt
     7081 agccatgttt ttctcctatt ttcttcttta taatatttaa ttgtatacgt ttttactact
     7141 tttgtcaata aaaaaacatg tattcaacga aaataattag ttcagaattt tagcttcaga
     7201 attttcttac ttcctttttg aatccgataa tatataggtt ttactagtct ctacaccata
     7261 aatatttgct aataaaaata ctgtattatt accctcttaa ggtgcgaaat tattcaagtt
     7321 cttaaaaaat gcttctctat ttccgtaaga tagcttattt cttcgattta agaactgaag
     7381 atgatagttc taacctttag aaatccaagc cttcactagc tcaaaaactc ctatctttct
     7441 tcctcaataa atcatctgag agataggtat tccttatgtc cttcaaattc atcactcctt
     7501 tggatattga ggtgctagcc tagaagcaga cacccgatta tctaaaccat ccttaataaa
     7561 gatgacaaga cagataagct cagttaatta cttatatatc tttttaatat ggtatatttg
     7621 tcaacaaaaa gaaatcaaat cataccttat actcaatgaa aatcaaagag caaactagga
     7681 agctagccgc aagttgctca aaacactgtt ttgaggttgc
//
LOCUS       DAYYYC010000074         7329 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.074, whole genome shotgun sequence.
ACCESSION   DAYYYC010000074 DAYYYC010000000
VERSION     DAYYYC010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7329
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.074"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(82..504)
                     /gene="nusB"
                     /locus_tag="ACHBV5_001969"
     CDS             complement(82..504)
                     /gene="nusB"
                     /locus_tag="ACHBV5_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFM9967710.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREYT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(497..886)
                     /locus_tag="ACHBV5_001970"
     CDS             complement(497..886)
                     /locus_tag="ACHBV5_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFM9967711.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            complement(908..1468)
                     /gene="efp"
                     /locus_tag="ACHBV5_001971"
     CDS             complement(908..1468)
                     /gene="efp"
                     /locus_tag="ACHBV5_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFM9967712.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            complement(1597..3039)
                     /gene="gatB"
                     /locus_tag="ACHBV5_001972"
     CDS             complement(1597..3039)
                     /gene="gatB"
                     /locus_tag="ACHBV5_001972"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFM9967713.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            complement(3039..4505)
                     /gene="gatA"
                     /locus_tag="ACHBV5_001973"
     CDS             complement(3039..4505)
                     /gene="gatA"
                     /locus_tag="ACHBV5_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFM9967714.1"
                     /translation="MTFNDKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDTDNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSASVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILSAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            complement(4505..4807)
                     /gene="gatC"
                     /locus_tag="ACHBV5_001974"
     CDS             complement(4505..4807)
                     /gene="gatC"
                     /locus_tag="ACHBV5_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFM9967715.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            5020..6564
                     /locus_tag="ACHBV5_001975"
     CDS             5020..6564
                     /locus_tag="ACHBV5_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFM9967716.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            6819..7016
                     /locus_tag="ACHBV5_001976"
     CDS             6819..7016
                     /locus_tag="ACHBV5_001976"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967717.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            7127..7303
                     /locus_tag="ACHBV5_001977"
     CDS             7127..7303
                     /locus_tag="ACHBV5_001977"
                     /inference="COORDINATES: protein motif:HMM:NF013652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFM9967718.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
BASE COUNT         2036 a         1442 c         1702 g         2149 t
ORIGIN      
        1 tgaacatcaa aaaagaaagg acgaaatttg tcctttctcg agcttagctt ttcttcaacc
       61 cactacagtt gacaaagagc cttattgttc ttctgttaca aactggctga gcagtccatt
      121 gataaaacgg gcagattttt gatcggagaa gtcctttgca agctcgatag cttcattaac
      181 agcaaccagc tgaggagtgt caaatgaagt gatttcaaag actcccaagc gaaggaggtt
      241 tctctccacg agcgttaagc gttcaatggt ccaacctgct tttaaatgct gagtgatttg
      301 cttatctagt tcttcctttt tagcttgaac accagaaacg aggtctatca aaaaggctgg
      361 aagttgtaca tccgtatatt cacgatcatg agtataggcg aaacgacaag cagtttcgac
      421 atccgtaccg aactcaaggc tcatgagagc ttgaaaagcg catttacgga gttggcgtct
      481 agattctaat agtggactag tcattgagga agtcctcgtc aaatagatct ttcaattctg
      541 gttttggtgt tttatctggg acgatacctg caacgtgaat attgatagca gcgagttcta
      601 catcagccat attacggacg gcatctttga cagctttctg gatagcaacc gctaccttag
      661 gaacttttac tccgtactca aggtagagat agatatctgc tgtgagttct tcgtccacgt
      721 ttttaagata aatgccacgg ccgagtgaaa gttttgaaag ggtatcagac actgatctgt
      781 ttgaaaaaga gtgaacaccc tctacctttg cagtagcgat agcaatgatt ttttcaagta
      841 cacgtggggc gataacgatt tcgccaagtt gttcttcaat tcccatagaa tgacctcttt
      901 ctagagatta ggcacgagaa acgtaagttc cttctgcagt gttgataacg agtttttgtc
      961 ctgcttcgat gaagtctgga acgtttacga caagtccagt ttccatcgtt gctggtttac
     1021 cagaacctgt aacagtagca cctttgatag atggttgagt ttcagcaact gtcaactcaa
     1081 cagtagtagg aacggtgaca ccgatcactt cagttccgta gaattggatt ttcacatcag
     1141 agttttcaag gatgtaaagc aattcgtttt caacattgac tacagggatt tcgtattggt
     1201 cgtaagtttc tgtattcatg aagtatgctg tgtcatccat tttgtacaag tattgagctg
     1261 ggacagtctc gataatagct tgttcaaatt tttcctctgg acggtagctt gtgtcaaatg
     1321 tagaaccagt acggacatca cgcaatttca tacgcatgat cgtgtttcct ttacctggtt
     1381 tgtggtgact agcttccaaa acgcgaatca atttgccgtc agctgtttca aaggtcatac
     1441 cagcttttaa tttacttgct tcaatcatgt ttttacctct ttaataaata ttattactct
     1501 tcattttacc ataaaatact ctggaaataa agccaaaata gttattggga gttggtagag
     1561 aagaaaaaac caaccttagg gctggttttg ttctgtctag ttttctttca acttcgccaa
     1621 ttcctgtgca agtagtttaa gggcaacttg tgggttggct tggcctttgg ttgccttcat
     1681 aaggaatcct gtaaaggcct tgtcggcgtt acgtttgcct gacttgaagt cggcaacagc
     1741 agcttcgtta tcggcaaaga cttggtggat gattgggatc aagatagctg gatctgaaat
     1801 ttgaaccata cctgcttttt ccacgtattc acgcgcgcca ccgccatttt tagctagatg
     1861 gacaaagact ttcttggcaa tcttagatga aatagtaccg tcttcgatga tggtaatcat
     1921 ttcaaccaag ttttctggtg tcaattcgat ttgttccagt gttttacctt cagcattcaa
     1981 gaactgagcg acttcccctt ggagccagtt agagacttgt ttggcatcac cacctagggc
     2041 aacagctttt tcaaagaagt cagaagtgac tttattagca gtcaactgac tagcatcgta
     2101 gtctgataaa ccaaggtcag atacataacg cgcacgacgt tcttttggaa actctggcaa
     2161 ctcagtccgc atttcctcaa tccactcgtc agaaatttca aagaggggta ggtctggttc
     2221 tgggaagtag cggtagtcag cagccccttc cttgacacgc atgaggatgg ttgttttgtt
     2281 agcttcatcg taacggcgtg tttcttggcg gatttgacca cctgagcgaa gaatttcagc
     2341 ctggcgttgg acttcgtatt caagaccttt acgaacgttt gagaaggagt tgaggttctt
     2401 caattcagtc ttggtaccga atttttcttg accataagga cgaagggaga tgttggcatc
     2461 cacacgcata gaaccttctt ccatcttaac gtcagaaatg ccagcgtact ggataacttc
     2521 cttgagggct gtcagataag cataggcttc ttcaggagaa cgcatatctg cctcagatac
     2581 aatctcaatc aagggaaccc cttggcggtt gaggtcaaca taagagtagc catctgtacc
     2641 atgggtgttt ttaccagcgt cttcctctaa gtgggcacgt tcgataccga ttttcttggt
     2701 cgtaccgtct tctagtttga cttcaatcca gccattatat ccgattggtt catcaaattg
     2761 agaaatttgg taggctttgg ggttatcagg atagaagtag ttcttgcggt caaagtgcat
     2821 ctttttgtgg atgtccatgt tgagggcaag agcagccttg ataccggcat caacaacccc
     2881 tttattgaga actggtagaa ctcctgggaa agaccagtca attacgttag tgttggcatt
     2941 ttggtcattt ccgaagtggg cagaagtagg tgagaagatt tttgaattgg tgttgagctc
     3001 tacgtggact tcaagtccga tgactgtttc aaagttcatt agttgtcacc tccaaaaatc
     3061 acgggttgtt gtttgtggta gtctgttgtt gcttcaaaag cagcagcagc ttggtaaatg
     3121 gtttcctcag agtacttggg accaatcaat tggagtccga caggtagacc ttgagagaat
     3181 ccagcaggaa tcgaaattcc aggcagtcct gccaagttta caggtatggt caagaggtcg
     3241 gctaagtaca tggcaactgg gtcatggttg agagaatcca agtcataggc aacacttgga
     3301 gcagttggac ccaaaatcaa atcgtaatcc gcgaagactt tttcgaaatc ttgaatgata
     3361 agtgtacgga cctgtccagc cttcttgtag taggcatcgt agtaacctga tgaaagactg
     3421 aaagtaccca gcatgatacg acgttttacc tcttcaccaa aaccttggct tcggctgttt
     3481 acatagattt catcaaggtt ggttgcatct tctgcgcgat agccgtaacg gataccgtca
     3541 aagcgttgca agtttgatga agcttctgat gaagcgatga tgtagtatac ggcaactccg
     3601 tatttagagt gaggaaggct gacttcttcg acaatagcac caagtttttc aaagtgttta
     3661 gcggcactta gaatggtttc cttaacctct gggttaattc cttcaccgag gtattcctta
     3721 ggcaaagcga ttttcatacc cttgatgtct tggccgattt ttgaagtaaa gtcggcgatg
     3781 cggacagaag cagaagtaga gtctttagca tcttcgctgg caatagcgtt gagcaagagg
     3841 gcattttcct taacagtagg agcaaaaggt ccaatctggt ctaatgagct gccaaaggca
     3901 atgagaccga aacgtgaaac tgttccgtag gttggtttga gaccaacgat tccgttgaag
     3961 gcagcaggtt ggcggatgga accaccagta tcagaaccaa gtgacaagcg aacttgtcct
     4021 gaggctacag ctgcggcaga accacttgat gacccaccag gaaccttgct gtggtcccaa
     4081 gcgtttttag ttgctccgta gtgtgaagtt tcacctgaac cacccatagc aaattcgtcc
     4141 atgttggtct ttccaacgac aatcatgccc ttggtttttg cattggcaac agctgtcgca
     4201 tcaaagattg gctcatagtt gtagagcatt tttgaggcag cagttgtgag aataccgtct
     4261 gtagagatgt tatccttaac agcaagtgga attcctgaaa ggacattgtc agtatcaatt
     4321 ccagcttcat caatggcttt agcttgaaca agagcttgct cctcagcgat ggtgacaaat
     4381 gaattgaggg cttcctcacg agacttgata ttttcaagtg ttgcttgggt caattctgtt
     4441 gcagaaattt ccttagagac aaggagattg tgcaactctt caatagtttt atcgttaaaa
     4501 gtcattaggc atctcctcca tcgtctagga tagctggcac cttgatatag tagttgtctt
     4561 tttcaggtac gtttttaaac aagcgatcac ggtctgttcc ttcttcggcc acatcagggc
     4621 ggagtacagt cttgcggtca gccatagtcg tagtaggtgc gacaccagtt gtgtcaactt
     4681 cgcccagcaa ttcaaccatg tcaacaatct tagacaaggt ggtcgcaaag gcagcagttt
     4741 cttcttcaga gaatcttaat tttgaaagat tggcaacgtg tgttacctct tcttgcgtaa
     4801 ttttcatctt gcatcctttc gtgaaatgat gatttttagt ctgttctatt ttaccatatt
     4861 ttcctataaa taagggaggg ggaagtgaaa agaaatagaa attgaaaaaa atgctaaaat
     4921 ccgatataat ggagtgttga aaggaatggt aaaatccaat gtaaaaatca ttctcagcta
     4981 ttgaaacaag aaaaatagag aatcaaagaa agagaactta tgaatattca agaagaaatt
     5041 aagaaacgtc gtacctttgc cattatctcc cacccggacg cggggaaaac aaccatcact
     5101 gagcagttac tctactttgg gggtgagatt cgtgaggctg gtacggtaaa agggaagaaa
     5161 acagggactt ttgctaaatc tgactggatg gatatcgaga agcaacgtgg gatttctgtt
     5221 acttcatctg ttatgcaatt tgactacgac ggcaagcgcg tgaatatctt agacacgcca
     5281 gggcacgagg acttctcaga agatacctat cgtaccttga tggcggtgga tgctgcggtc
     5341 atggtcgtgg actctgccaa ggggatcgag gctcaaacca agaaattgtt tgaggttgtg
     5401 aaacatcgtg gcattccagt ctttaccttt atgaacaagc tggaccgtga cggtcgtgag
     5461 cctttggatc tcttgcaaga attggaagaa atcttgggca ttgctagcta ccctatgaac
     5521 tggcctatcg ggatggggaa agcctttgag ggcttgtatg acctctataa ccaacgttta
     5581 gagctttata aaggggatga gcgttttgcc agtctagaag acggggacaa actctttggt
     5641 agcaatcctt tctacgagca agtcaaggat gacattgagc ttttaaatga agctgggaat
     5701 gagttttcag aggaagctat tctggctgga gaattgacgc ctgtcttttt cggttcagcc
     5761 ctgacaaact ttggtgtgca gaccttcctt gaaatcttcc tcaagtttgc tccagaacca
     5821 catggtcaca agaaaacaga cggtgaaatt gtggatcctt atgacaagga tttctcaggc
     5881 tttgtcttta aaatccaagc caacatggat cctcgtcacc gtgaccgtat tgcctttgtc
     5941 cgtatcgtat caggcgaatt tgagcgcggc atgagtgtca atctccctcg tactggtaag
     6001 ggggctaaac tatctaatgt tacccagttt atggcggaga gtcgtgagaa tgtgaccaat
     6061 gccgtggcag gtgatattat cggggtttac gataccggta cttatcaggt tggggatacc
     6121 ttgacggttg gaaaaaacaa gtttgaattt gaaccactgc caacctttac tcctgaaatt
     6181 ttcatgaaag tttctgctaa gaatgttatg aagcaaaaat ccttccacaa ggggattgag
     6241 caattggtgc aagaaggagc cgttcagctt tataagaatt accaaacagg tgagtacatg
     6301 ctgggagctg ttggtcaact ccagtttgaa gtctttaaac accgtatgga aggcgaatac
     6361 aatgcggaag tggtcatgag cccaatgggt aaaaagaccg ttcgttggat caagcctgag
     6421 gacttggatg aacggatgtc gtcaagtcgc aatatcttag ccaaagaccg ttttgaccaa
     6481 ccagtctttc tctttgaaaa tgactttgcc ctccgctggt ttgcggacaa gtatccagac
     6541 gtagagttag aggagaagat gtgactcagt accaacaatt ggaactaaag ttccaaattg
     6601 ttggacgcta gtcgctattt ggcgaactag ctaactgcct cactaactac gtttggcaaa
     6661 tgaaatcgat ttgtaaaact ccgtgtcgta atgtaaaaat tgtaaaccgt aatgggactt
     6721 catctaaaat ctccactggt atggttttac gaacgaatag gcgaaaataa tggttacgta
     6781 gaaacatatg atgggaataa aaagaaatga gataaaaagt gaaagaagag aaaaaagcga
     6841 ttgtcttagg tgcagataat gcttatatgg ataaagttga aacaacaata aaatctcttt
     6901 gtgttcatca ttataatctt aagttttatg tttttaatga tgaccttccg cgagaatggt
     6961 tccaattgat ggaaaaaaga ctagagactt tgaatagtga gattgtgaat gtttagattg
     7021 acagtaatat tctgaaaggt tatcgtctcc cctttgaggg actttcatat gcggcttttt
     7081 taggtatttt attccaaagt atgtaagcga gtctcgtgta ctgtatttgg attcagatat
     7141 tgttgtaaga aaatcgatag atgagctgtg ggatttggac ttgacggcta tacccttagc
     7201 tgcagttaga gatgattttt atacacataa ttttaattct ggtgttctgt taatcaacga
     7261 tggcatgtgg agagcagaaa atgtcacgca agacctgatt taagacacaa ataaaaaatc
     7321 ttccaattc
//
LOCUS       DAYYYC010000075         6903 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.075, whole genome shotgun sequence.
ACCESSION   DAYYYC010000075 DAYYYC010000000
VERSION     DAYYYC010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6903
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.075"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            1..511
                     /locus_tag="ACHBV5_001978"
                     /pseudo
     CDS             1..511
                     /locus_tag="ACHBV5_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            678..878
                     /locus_tag="ACHBV5_001979"
     CDS             678..878
                     /locus_tag="ACHBV5_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967719.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            903..1319
                     /locus_tag="ACHBV5_001980"
     CDS             903..1319
                     /locus_tag="ACHBV5_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967720.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLDVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1550..2257
                     /gene="ccdA2"
                     /locus_tag="ACHBV5_001981"
     CDS             1550..2257
                     /gene="ccdA2"
                     /locus_tag="ACHBV5_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HFM9967721.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2268..2825
                     /gene="sdbB"
                     /locus_tag="ACHBV5_001982"
     CDS             2268..2825
                     /gene="sdbB"
                     /locus_tag="ACHBV5_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HFM9967722.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2946..4337
                     /locus_tag="ACHBV5_001983"
     CDS             2946..4337
                     /locus_tag="ACHBV5_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFM9967723.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4480..5397
                     /gene="adcAII"
                     /locus_tag="ACHBV5_001984"
     CDS             4480..5397
                     /gene="adcAII"
                     /locus_tag="ACHBV5_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HFM9967724.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5405..>6903
                     /locus_tag="ACHBV5_001985"
     CDS             5405..>6903
                     /locus_tag="ACHBV5_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HFM9967725.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITYRTVNGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLG"
BASE COUNT         2148 a         1255 c         1442 g         2058 t
ORIGIN      
        1 ggagagctaa accaccaagt aaaaggaaca aaaccaagaa aagttgatag agatagactt
       61 aaaaactatc ttactgacaa tccagacgct tatttgactg aaatagcttc tgaatttggc
      121 tgtcatccaa ctaccatcca ctatgcgctc aaagctatgg gctacactcg aaaaaagaac
      181 cacacctact atgaacaaga cccagaaaaa gtagccttat ttcttaagaa ttttaatagt
      241 ttaaagcacc tagcacctgt ttagattgac gaaacaggat tcgatactta tttttatcga
      301 gaatatggtc gctcattaaa aggtcagtta agaagaggca aagtatctgg aagaagatat
      361 cagagaattt ctttggttgc aggtctaaca aatgaatggt gagttaatcg ctccaatgac
      421 ttacgaagag acgatgacga gcgacttttt tgaagtatgg tttcagaaat ttctcttacc
      481 aacattaacc acaccatcgg ttattatagt aaaatggaat aagaacagga caaatcgatc
      541 aggacagtaa aatcgaattc taacaatgtt ttagaagtct atatgtacta ttctagtttc
      601 aatataccat aactgctcct agtcaacctg caagtcctgt cccagctcca agctcagctc
      661 cgactcaaga tcctagagtg gtagcaagcg cttcggctag ctcaacgagc acacaagctc
      721 aagagcaagt tgacaagtct gaacttcgtg ccttgagtca agagttagac caacgcttga
      781 aagctttggc aacagtatct gatccaaaaa tcgatgcaac caaggctgtc ctcctagatg
      841 ctcaaaaagc tccggaagat agtgccttga cagagtaagg tctgcatact gcagtagagt
      901 ctgtgaaggc tgccttggac tctctcaaag atgtgaaagc aaatgctagc gacagcaagc
      961 ctgcacagga caagaaggat gcaaaacaag gaacggaaga tagtaaggat tcagataaga
     1021 tgactgaaac aaactcagtt ccggcaggag tgattgtggt cagtctactt gccctcctag
     1081 acgtgattgc cttctggctg attcgccgta agaaagagtc agaaatccag caattaagca
     1141 cggaattgat caaggttcta ggacagctag atgcagaaaa agcggataaa aaagtccttg
     1201 ccaaagccca aaaccttctc caagaaaccc ttgatttcgt gaaagaagaa aatggctcag
     1261 cagagacaga aactaaacta gtagaggagc ttaaagcaat ccttgacaaa ctcaagtaaa
     1321 acatgattta tgaaatgtca gacctaaaag acattttcgt tcacaaaagc agtgacgagt
     1381 aatccttgtc gttgcttttt ggctattttg ggggataaga tccgccttga ctagcaaaag
     1441 aaaagattgg tccaatagtg cccgatacga ttttgcgtag cagaaagctt acaaataaaa
     1501 ttgaatatag taaaatagga ttagaattat taagaaagtt ggttctttat tggaaacgat
     1561 agtattttta atctctgttt ttctagcagg tgttttatcc tttttttctc cttgtatttt
     1621 tcctcttctg ccagtctatg ctgggatttt attggatgat caagaaagtg caaaaagctt
     1681 ttctttgttt gggagaaagg ttctctggtc aggcttgatt cgaacacttt gctttatcgc
     1741 tggtatctct ctcattttct ttattctagg ctttggtgct ggttactttg gtcatattct
     1801 ctatgcaaat tggtttcgat atgtcatggg agctattatt atcattttgg gtcttcacca
     1861 gatggaaatt tttcatttga agaaattaga agttcaaaaa agttttacct ttaaaaaatc
     1921 agattctaat cgttattggt cagctttttt acttggtatt acctttagct ttggttggac
     1981 accttgtatt ggtccagttt taagttctgt tttagcactt gcggcttctg gaggcaatgg
     2041 tgcttggcaa ggagcgattt atactctcat ttacactctg ggcatggccc ttcctttctt
     2101 ggtcttggca ctagcttcag gtctagtcat gccatatttt agtaaaatca agcgtcatat
     2161 gatgctacta aagaaaattg gtggtttcct cattgtttta atgggaattt tgttactatt
     2221 aggacaagta aatgttctag ctggaatttt tgaataaagg aggacaaatg aaaaaagtaa
     2281 tgtttgctgg cttaagtctc ttgtcattag ttgtattgat ggcctgtggt gaggaagaaa
     2341 ctaaaaagac tcaagcagca caacagccaa aacaacaaac gactgtacaa caaattgctg
     2401 ttggaaaaga tgctccagac ttcacattgc aatccatgga tggcaaagaa gttaagttat
     2461 ctgattttaa gggtaaaaag gtttacttga agttttgggc ttcatggtgt ggtccatgca
     2521 agaaaagtat gccagagttg atggaactag cggcgaaacc agatcgtgat ttcgaaattc
     2581 ttactgtcat tgcaccagga attcaaggtg aaaaaactgt tgagcaattc ccacaatggt
     2641 tccaggaaca aggatataag gatatcccag ttctttatga taccaaagca accaccttcc
     2701 aagcttatca aattcgaagc attcctacag aatatttaat tgatagccaa ggaaagattg
     2761 gaaagattca atttggtgct atcagtaatg cggatgcaga agcagcattt aaagaaatga
     2821 actagaatcg ataaaatctg attacaagat gtagtcagat ttttttagaa aaacatttta
     2881 taaatattca catatctcct atatttatgg taaaatagaa ttatcagttt attttggagt
     2941 caaagatgaa tatatttaga acaaagaatg ttagtttaga taaaacagag atgcataggc
     3001 atttgaagtt atgggatttg attttgctgg gtatcggagc catggtaggg acaggcgtct
     3061 ttacaatcac aggtactgca gctgcaacac ttgctggccc agccctagtg atttcaatcg
     3121 ttatttctgc cttgtgtgtg ggattatcag ccctcttttt tgcagaattt gcctcgcgag
     3181 tacccgctac aggaggtgcc tatagttacc tctatgctat cttaggagaa ttccctgcct
     3241 ggttggctgg ttggttaacc atgatggagt tcatgacagc catatcaggc gtagcttcgg
     3301 gttgggcagc ttattttaaa ggcttgctct ctcaatacgg gatagccttt cctcaggctt
     3361 taaatggtac ctttaatcct caagcaggga catttgttga tttattgcct attcttgtct
     3421 tggtcttggt gacttcgctt gttttactaa atgccaaggc agccttacgc tttaattcga
     3481 ttctagttat tttgaaattt tccgctttag ctctctttgt tttagtagga atttggaata
     3541 ttaagtttga taattggagc aattttgctc cttacggttt tggacaaatc tatggagcta
     3601 gcactggtat tatggctggt gcgtccttga tgttcttcgg ttttttggga tttgaatcca
     3661 tctctatggc tgtagatgaa gtcaagactc ctcaaaaaaa tattcctaga gggattgtct
     3721 tatcgctttc tatcgtaacc attctctatg ccttggtgac ccttgttttg actggtgtgg
     3781 ttcactatag tcatttaaat gtcgatgatg ccgttgcctt tgcccttcgt agtgttggga
     3841 ttagttgggc agccaactat gtgtcattag tggctatctt gaccttgatt acagtttgta
     3901 tttcgatgac ctatgcccta tcgcgtatga tttacagttt agcacgtgac ggcttagtgc
     3961 ctgctgcctt taaggaactg acgaagacta gcaagatacc aaagaatgct actatcttga
     4021 caggtctagc ttcagcagta gcagcaggaa tgttcccact agccagtatt gcagcctttt
     4081 taaatatttg taccttagcc tacttgatca tgctggctta tggtctgatt cgcttacgga
     4141 aagaaaaagg aatgcccaaa gctggggaat ttaaaacacc attggtacct ctgttaccaa
     4201 ttttatcgat catcatttgt ttatccttca tgttacagta taatatgaac acctggattg
     4261 ctttcctagt tgcgttgtta gtaggaagta ttatttactt cacttatggc tataagcatt
     4321 ctaccataga agaataaagt gaaagtctat tgagttgttg acactcagta gatttttata
     4381 tgtgaaagaa atttcaaatt ttttctaaaa atatcttgac agattaaatt ttcaggagta
     4441 gaatatttac tagttaatta aatggttaag gagttgttca tgaagaaaca aaatttattt
     4501 ttagtcctgt taagtgtctt tcttttgtgt ttgggggctt gtggtcaaaa ggaaagtcag
     4561 acaggaaagg ggatgaaaat tgtgaccagt ttttatccta tctacgctat ggttaaggaa
     4621 gtatctggtg acttgaatga tgttcggatg attcagtcaa gtagtgggat tcactccttt
     4681 gaaccttcgg caaatgatat cgcagccatc tatgatgcag atgtctttgt ttaccattct
     4741 catacactcg aatcttgggc aggaagtctg gatccaaatc taaaaaaatc caaagtgaag
     4801 gtcttagagg cttctgaggg aatgaccttg gaacgtgtcc ctggactaga ggatgtggaa
     4861 gcaggggatg gagttgatga aaaaacgctc tatgaccctc acacatggct agatcctgaa
     4921 aaagctggag aagaagccca aattatcgct gataaacttt cagaggtgga tagtgagcat
     4981 aaagagactt atcaaaaaaa tgcgcaagcc tttatcaaaa aagctcagga attgactaag
     5041 aaattccaac caaaatttga aaaagcgact cagaaaacat ttgtaacaca acatacagcc
     5101 ttttcttatc tagcgaagag atttgggctt aatcaacttg gtattgcagg tatctctcct
     5161 gaacaagaac caagtccacg acaactaaca gaaattcagg aatttgttaa gacctataag
     5221 gttaaaacga tttttacaga aagtaacgct tcttcaaaag tagctgaaac tcttgtcaaa
     5281 tcaacaggtg tgggtcttaa aactctgaat cctttagagt cagacccaca aaatgacaag
     5341 acctatttag aaaatcttga agaaaatatg agtattctag cagaagaatt aaagtgagga
     5401 aagaatgaaa atcaataaaa aatatctagc aggttcagtg gcagtccttg ccctaagtgt
     5461 ttgttcctat gaacttggtc gtcaccaagc tggtcaggtt aagaaagagt ctaatcgagt
     5521 ttcttatata gatggtgatc aggctggtca aaaggcagaa aatttgacac cagatgaagt
     5581 cagtaagaga gaggggatca acgccgaaca aattgttatc aagattacgg atcaaggtta
     5641 tgtgacctct catggagacc attatcatta ctataatggc aaggttcctt atgatgccat
     5701 catcagtgaa gaacttctca tgaaagatcc gaattatcag ttgaaggatt cagacattgt
     5761 caatgaaatc aagggtggct atgtgattaa ggtagacgga aaatactatg tttaccttaa
     5821 agatgcagcc catgcggaca atattcggac aaaagaagag attaaacgtc agaagcagga
     5881 acgcagtcat aatcacaact caagagcaga taatgctgtt gctgcagcca gagcccaagg
     5941 acgttataca acggatgatg ggtatatctt caatgcatct gatatcattg aggacacggg
     6001 tgatgcttat attgtccctc acggcaatca cttccactat attcctaaga gtgatttgtc
     6061 tgccagtgaa ttagctgctg cccaagccta ttggaatggg aagcagggat ctcgtccttc
     6121 ttcaagttct agtcataatg caaatccagc tcaaccaaga ttgtcagaga accacaatct
     6181 gactgtcact ccaacttatc atcaaaatca aggggaaaac atttcaagcc ttttacgtga
     6241 attgtatgct aaacccttat cagaacgcca tgtagaatct gatggcctag tatttgatcc
     6301 ggcacaaata acatatcgta cagtcaatgg tgttgctgta ccgcacggag accattatca
     6361 ctttattcct tattcacaac tgtcaccttt ggaagaaaaa ttggctcgta tgattgctgt
     6421 taagggacaa aatggtgcag tcttgccagg aatgcattat ttgaaaccag caccaaaacc
     6481 gcaagttcaa ccatcaactg agaaaaaaca aactgatttt gcagtagaac aggttgttag
     6541 aaaagttgga gaaggctatg ttgtggaaat tgctggtgtc agtcactatg tttttgctaa
     6601 agacttggct aaggataaga ttgatgctat tgaaaatctc ttgtctaaga aaactcaaga
     6661 gacacatgct ctagttgcta aaaaagaaaa tgtcgctcct cgtgaccaag aattttatga
     6721 taaagcttac aatctgttaa cccaggctca taaagtcttg tctgaaaata aaggtcgtac
     6781 ttctgatttc caagccttag acaaattagc agaacgcttg aataatgaat cttctaataa
     6841 agtaaaattg gtagatgatt tattggcatt cctagcacca attacccacc cagaacgcct
     6901 tgg
//
LOCUS       DAYYYC010000076         6608 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.076, whole genome shotgun sequence.
ACCESSION   DAYYYC010000076 DAYYYC010000000
VERSION     DAYYYC010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.076"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..88
                     /locus_tag="ACHBV5_001986"
     CDS             <1..88
                     /locus_tag="ACHBV5_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HFM9967726.1"
                     /translation="SDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            78..1217
                     /gene="glgD"
                     /locus_tag="ACHBV5_001987"
     CDS             78..1217
                     /gene="glgD"
                     /locus_tag="ACHBV5_001987"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HFM9967727.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            1214..2647
                     /gene="glgA"
                     /locus_tag="ACHBV5_001988"
     CDS             1214..2647
                     /gene="glgA"
                     /locus_tag="ACHBV5_001988"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HFM9967728.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            2706..3350
                     /gene="serB"
                     /locus_tag="ACHBV5_001989"
                     /pseudo
     CDS             2706..3350
                     /gene="serB"
                     /locus_tag="ACHBV5_001989"
                     /inference="COORDINATES: protein motif:HMM:NF012905.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0036424 - L-phosphoserine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
     gene            3359..4475
                     /locus_tag="ACHBV5_001990"
                     /pseudo
     CDS             3359..4475
                     /locus_tag="ACHBV5_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(4472..4918)
                     /locus_tag="ACHBV5_001991"
     CDS             complement(4472..4918)
                     /locus_tag="ACHBV5_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFM9967729.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            5082..6386
                     /gene="eno"
                     /locus_tag="ACHBV5_001992"
     CDS             5082..6386
                     /gene="eno"
                     /locus_tag="ACHBV5_001992"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HFM9967730.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFLGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            complement(6393..>6608)
                     /locus_tag="ACHBV5_001993"
     CDS             complement(6393..>6608)
                     /locus_tag="ACHBV5_001993"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967731.1"
                     /translation="SEYQKRKDKICPFSSLAFFQPTTVDKEPKSFVPFLPSKYKNSPS
                     DKIRGARNVVKSTAELLNFMVRDKIVH"
BASE COUNT         1971 a         1196 c         1433 g         2008 t
ORIGIN      
        1 ttctgacggt gtcgaaattg atggaacaga tgaagtacaa gttgtaggat ataatgaagt
       61 agtgggggta gcaacagatg aagattgata aatattctgc cattttagga aatacagttg
      121 gttttcacaa tatgtcgaca ttgacggacc accgtccagt agcaagtttg ccatttggtg
      181 ggaaatatcg tttgattgat ttcccacttt caagccttgc taatgcaggt gttcgtagtg
      241 tctttggtat tttccagcag gataatatca gctcagtatt tgaccatatt cgttcaggac
      301 gcgagtgggg cttatcaacc cttcttagcc attactatct aggaatttac aatacccgtg
      361 tagaaagtag tacagttgga aaagaatact accaacagct tcttacttat ttgaaacgtt
      421 ctggctcaaa ccaaacggtt gccctcaact gcgatgttct tattaacatt gatttgaacc
      481 aagttttcca cctacatagt acaacaaaag agcctatcac tgtagtttat aaaaaactag
      541 ctaagaaaga tatttcagaa gtaaatgcaa tcttggatgt agatgaaaca gaccatgttc
      601 tttctcataa actctttgat agcaagtcaa cagctgaaac gttcaatatg tctacagata
      661 tctttgtcgt tgatacacct tggttgattg aacacttgga agaagaagct aaaaaagaac
      721 atccagagaa attgcgctat gttttacggg atttggctgt aaaagaggga gctttcgcct
      781 acgagtacac gggctatcta gccaatattc actctgttaa atcttattat caagcgaata
      841 tcgatatgct tgaatcacaa aaattctatt ctcttttctc accaaaccaa aagatttata
      901 caaaggtcaa aaacgaagag ccaacttact atgctaatac atctaaggta agcacttctc
      961 agtttgcctc tggtagtatt attgaaggtc aagtagctaa ttctgttcta tcacgtaata
     1021 ttcatgtcca taaggatagc ttggttaaag atagcctgct cttccctcgt gttgttattg
     1081 gagaaggggc tcaggtcgaa tatgctatct tggacaaagg ggttgaagtt gagcctggtg
     1141 ttgtgattcg aggaactgca gaacatccag ttgtggttaa gaaaggtgct aaagtaacag
     1201 aggatattca ttcatgaaaa ttttatttgt agcagcagag ggtgcaccct tttcaaaaac
     1261 aggtggtttg ggagacgtca ttggcgctct tccaaaatca ctggtaaaag ctgggcacga
     1321 agttgcagtg attttaccct actatgatat ggtagaggct aaatttggaa atcagattga
     1381 agatgtgctt cattttgagg tgagcgttgg ttggcgcaga cagtattgtg gaattaagaa
     1441 aacagtatta aatggtgtaa ccttctactt tattgacaat caatattatt tcttccgtgg
     1501 tcatgtttac ggtgattttg atgacggaga acgctttgcc tttttccaac tggctgccat
     1561 tgaggctatg gaaaggattg actttattcc tgatcttctc catgttcatg actaccatac
     1621 agctatgatt cctttcttgt tgaaggaaaa ataccgttgg attcaagcct atgaggacat
     1681 tgaaacagtt ttaaccattc ataatttaga attccaagga caattttcag aaggaatgtt
     1741 gggtgatttg tttggagttg gctttgaacg ttacgctgat ggcacccttc gatggaacaa
     1801 ctgtctgaac tggatgaagg caggtattct ctatgcgaac cgtgtttcaa ccgtttcacc
     1861 tagctatgct catgaaatta tgactagtca gtttggatgt aatttggatc agattcttaa
     1921 aatggagtct ggtaaagtat ctggtatcgt gaatgggatt gatgctgatc tttataatcc
     1981 tcagacggat gctcttttag actatcattt caatcaggaa gatttgtctg ggaaagccaa
     2041 aaataaggca aaattgcaag aaagagttgg cttgcctgtt agagcagacg ttccactggt
     2101 gggaattgtt tctcgtttga cacgtcaaaa aggttttgat gtggtggtcg aaagtcttca
     2161 ccatatcttg caagaagatg ttcagattgt tcttttggga actggcgatc cagcctttga
     2221 aggagctttc tcatggtttg ctcagattta cccagacaag ctatcaacaa atatcacttt
     2281 tgatgtcaaa cttgctcagg aaatctacgc tgcttgtgac ctcttcctca tgccaagtcg
     2341 ttttgaaccg tgtggcttgt ctcaaatgat ggctatgcgt tatggaacct tgccattggt
     2401 ccatgaagtt ggaggcttgc gagatacagt tcgcgctttc aatccaatcg aaggaagcgg
     2461 tactggcttt agctttgaca atctatctcc ttattggtta aattggactt tccaaacagc
     2521 attggacttg tatagaaacc atccagacat ttggagaaac ctacaaaaac aagctatgga
     2581 gagtgacttc tcatgggata cagcctgcaa gtcatacctt gacttgtacc atagtttagt
     2641 taattaatag ataaaatcgt atgatgactt catacgattt ttaggctgtt tagagaggag
     2701 aactgatgtc tcaagtaaaa ggcttgtgtg ttttggatgt agatggaacc ttaatcctag
     2761 aagaagtgat tgatctttta gggagagagg caggtcatga ggcggaaatt tcgcagatta
     2821 caagtcgagc aatgcgagga gagttggtct ttgaaagcag tttaagaaaa agagtgtcct
     2881 tgttggaagg tcttcctatt ttggtctttg ataacgtctt caactcaatt catctatcgc
     2941 taaatgtccc agagttcatc tctattctcc aaaagaatgg catcctagtt ggtctggtgc
     3001 ctggtggatt tacaccaata gttggagaga ttagcaaaat cccttggtat tgcctatttc
     3061 actgccaacc agcttgaagt caaagaaggt ttttaacagg aaaattagtt ggacaaatta
     3121 taagtcccca ggtcaaaaaa gaaactctgg aaaaatggag aaagaaacta aaactttcta
     3181 aagaaagaac ggtggcaatc ggtgatgggg tcaataatct attaatgttg aagtcggcgg
     3241 agttaggaat cgccttttgt tccaaagaaa tgctcaaaaa agaaatacca catcatgttg
     3301 acaagaggga ttttttagaa gttcttcctt tgattgactg tttagaatga gggaaaatat
     3361 gaagattgta attgcaccgg attcgtttaa ggaaagcttg acagctcaac aggtagctga
     3421 agcaataaaa agaggcttcc aacaatcgat agcagatgta gaatatctcc tctgccctgt
     3481 tggtgatggg ggagaaggta ctgtagatgc tatccgacat tctcttgacc taaaagaaaa
     3541 atggatccaa gtgacagacc cttttggaca aaaagaagcc atgcgctatt ttcaaaaagg
     3601 ggaactggca ctatttgaag tagctgactt ggttggtctt ggaaaaattc cgctagagaa
     3661 acgaaatcca cttcaaatcc aaacttgtgg tattggagag ttgattctcc atctcatttc
     3721 taaagggatt aaagatattt atatcggtgt tggtagcacg gccagtaatg atggaggact
     3781 ggggattgct gctggtttag gttatcaatt ttatgatagg gatggaaatg tcttgcctgc
     3841 ttccagtcaa tccttattaa acttagcttc tgtttcaaca gaaaattgct ataaaattcc
     3901 tgaaggtgtt caaattcata ttctagcaga tgtcgtgagt cccttatgtg gtcatcaagg
     3961 tgcgacttac acttttggca atcaaaaagg tctacatccg actatgtttg cagtcgtaga
     4021 tcaggcgatc caagattttt atgaaaaatt ctcacctgca acattagaaa ttaaaggagc
     4081 aggagcaggt ggaggccttg ctggtggttt gtgtgccttt gctcaggcaa gtatcgtgtc
     4141 tggaattgat accttgcttg gacttaatca actttgataa gaaagtttca gatgctgact
     4201 tgcttgttgt tggagaagga agacttgaca gtcaaagctt tgctgggaaa gcgcctatag
     4261 gtgttgcaaa aagaacccct gttggagttc ctgttattgc tatttgcggt agtcttgctg
     4321 aagatttacc tcccctacca tttgaaaata tccaagctgt cttttctatt ttggagaaaa
     4381 gtgaaccttt agaagatagt ttgaaaaatg ccagtctcta tctggagcgc acggctgcca
     4441 atattgggca cttattaaat atgtgcaaga tttagctaaa ccatttcttc cataaggatg
     4501 ttttggctgg ttcttccttt ttaacttccc aaagttttgg aaaagcaagt cgaaggtctt
     4561 tttcttctac ttgaactggt gcattgctat gaataaccag gccaaaagga gaagtaatat
     4621 gctcttcaga tactatggtg gcttgactat cagtttcttt tgcttctttt aagtagaaaa
     4681 cttgcttatc aaattcgata gttggtgaaa tcttcacaaa tagtggctct gctttttcct
     4741 gaaggttttc taaaataaat aaaaagcctt tttctaactg agggctattt gctgtgtcaa
     4801 tatctacata tccaagaact ctttcctcaa aagtaccaag atagcgtctt tgctcatccg
     4861 gatttatttt taacccacca tgagcttttt caagtaattg ttttgataaa tctgtcatga
     4921 aaacagtata tcataaaagt tagaataaaa cagacaaaag aaagcgatta ctttataaag
     4981 ttaaggaaaa gttgcacaaa gataacgttt tttcttgaaa aaggaggggt tttaaggtat
     5041 tatagaggtg taaaaaattt aactcataag gagagtaaaa aatgtcaatt attactgatg
     5101 tttacgctcg cgaagtccta gactcacgcg gtaacccaac acttgaagta gaagtttaca
     5161 ctgaatcagg tgctttcgga cgtggtatgg ttccatcagg agcttctact ggtgaacacg
     5221 aagcagttga acttcgcgac ggtgacaaat ctcgttacgg tggtcttggt acacaaaaag
     5281 ctgttgacaa cgtaaacaac atcattgctg aagctatcat tggctacgat gtacgtgatc
     5341 aacaagctat tgaccgtgct atgatcgcac ttgacggtac tcctaacaaa ggtaaattgg
     5401 gtgcgaatgc aatcctcggt gtgtctatcg ctgtagctcg tgctgctgct gactaccttg
     5461 aaatcccact ttacagctac cttggtggat tcaacactaa agttcttcca actccaatga
     5521 tgaacatcat caacggtggt tctcactctg acgctccaat cgctttccaa gagttcatga
     5581 tcttgccagt tggtgcgcca acatttaaag aagcccttcg ttacggtgct gaaatcttcc
     5641 acgctcttaa gaaaatcctt aaatcacgtg gtttggaaac tgccgtaggt gacgaaggtg
     5701 gattcgctcc tcgtttcgaa ggaactgaag atggtgttga aactatcctt gctgcgattg
     5761 aagctgctgg atatgtacca ggtaaagacg tatttctcgg atttgactgt gcttcatcag
     5821 aattctacga taaagaacgt aaagtttacg actacactaa atttgaaggc gaaggtgctg
     5881 ctgttcgtac atctgcagaa caaatcgact accttgaaga attggttaac aaatacccaa
     5941 tcatcactat tgaagatggt atggatgaaa acgactggga tggttggaaa gctcttactg
     6001 aacgtcttgg taagaaagta caacttgttg gtgacgactt cttcgtaaca aacactgact
     6061 accttgcacg tggtatccaa gaaggtgctg ctaactcaat ccttatcaaa gttaaccaaa
     6121 tcggtactct tactgaaact tttgaagcta tcgaaatggc taaagaagct ggttacactg
     6181 ctgttgtatc acaccgttca ggtgaaactg aagattcaac aatcgctgat atcgcagttg
     6241 caactaacgc aggacaaatc aagactggtt cactttcacg tacagaccgt atcgctaaat
     6301 acaaccaatt gcttcgtatc gaagaccaac ttggtgaagt agctgaatat cgtggattga
     6361 aatcattcta caaccttaaa aaataaaata gttcagtgaa ctattttatc ccgaaccatg
     6421 aaattcaaaa gttcggccgt tgatttaaca acgtttctag cccctcggat tttatccgaa
     6481 gggctatttt tgtatttaga gggcaaaaaa gggacaaaac tttttggctc tttgtcaact
     6541 gtagtgggtt gaaaaaaagc taagctcgag aaaggacaaa ttttgtcctt tcttttttga
     6601 tattcaga
//
LOCUS       DAYYYC010000077         6323 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.077, whole genome shotgun sequence.
ACCESSION   DAYYYC010000077 DAYYYC010000000
VERSION     DAYYYC010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6323
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.077"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(616..1608)
                     /locus_tag="ACHBV5_001994"
     CDS             complement(616..1608)
                     /locus_tag="ACHBV5_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM9967732.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            1768..3522
                     /locus_tag="ACHBV5_001995"
     CDS             1768..3522
                     /locus_tag="ACHBV5_001995"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9967733.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNINNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            3506..5227
                     /locus_tag="ACHBV5_001996"
     CDS             3506..5227
                     /locus_tag="ACHBV5_001996"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9967734.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDVK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            5238..5822
                     /locus_tag="ACHBV5_001997"
     CDS             5238..5822
                     /locus_tag="ACHBV5_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFM9967735.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            5822..>6323
                     /locus_tag="ACHBV5_001998"
     CDS             5822..>6323
                     /locus_tag="ACHBV5_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFM9967736.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKIAMRVRGINF
                     KNPVKYL"
BASE COUNT         2230 a          895 c         1073 g         2125 t
ORIGIN      
        1 catatgattc tttctaatga gttgttttgt cgcttttcat tataggtcat atgggacttt
       61 ttttctacac aaaataggct ccataatatc tatagtggat ttacccacta caaatattat
      121 agaacccaaa aatgctctga aacactgatt tcaaggcatt ttttgttagt ttaaaattac
      181 tcccattctt cttttccaaa catacaatat atccaaaacc attcaaaata ctagattcta
      241 ttttttataa tatcactaaa tccacctaat tataggacgt tttcagattt ttagtcccgt
      301 cccagtccca gtaccggaga aatattgttt taatataata tctctttttg tcttctaagc
      361 tcttaaaagc aaaagaacaa gtaaagagtc aagacaagga taaaaagtcc atattagggc
      421 aaataaaaag ctttaagaca gatgacaaat ctaagtcaaa taagaaagac catagcaaag
      481 gtgcagagag ataaatattg gcggtcttcg gactgccttt atttttttat ccatttttca
      541 aatcaaattt attcagacta tatatgcaca tatacactta aattcatata aaaacatggc
      601 ttgtaaaaaa ttactttaat cacaataatc gcatttaaaa ttgtgatgtt tgcaagctaa
      661 attacggact tcacttggaa gttttccctt gtatctttta taatagatag aaaatttgct
      721 ggcagatgaa tatccaacag attctgctat ctcttttata ggtagttcag tgtttaaaag
      781 aagagtttca gctacattca ttctttttct ttgagtgtac tctgtaatgc tttgacaata
      841 tttttcctta aataaatttt ttaatttagt accactcatt ttagatattt tttcaagcgt
      901 gccttgattt acattcgttg caaaatgatc atctaagaat cttgctacat cttcaagtgc
      961 tttatcatca tcaatttcaa ttttatattt ttttctattt aagtatgtgt caattactat
     1021 acttatccat tcatttgcct ttgctttaaa gaaaaaatca gcggcaggag cgtccatctt
     1081 acaatttaat atttccattg ccactctttc taaggccttt gtaagtatta tttgattcgg
     1141 ttgaagcaag gttgaataaa aagattctgg attaatgtta atagatgcta aatgtttttc
     1201 tattagctct tttttaaaac caatggaaac agcaagataa caacaattct cgtgtaataa
     1261 aaaaacaaaa tcatctttta tattatcaaa atcaaaagta cataaagagt ttgcggtaat
     1321 agtttgatac ggattaaact tttctccgtt tgcactgaca atgtaacttg aataaattga
     1381 aacatagtct gacatactat aagtgctatt ttgaactact tcctctttga tataaaaatc
     1441 atgtatatcg ataatgaagc tgcctccttc ataaaaccaa tataggcctt ctgcataagt
     1501 tgaattctct tttttccaac aaaatgtatg acctgcactt gaatacttct cattgttttt
     1561 acattcatct actttcatat aatcttttac aaaatcataa tatgacataa cacactatcc
     1621 cttttagaca atattccaat tagctttatt aattcaaaac tattgtatta gtaattataa
     1681 cagatgtata atagaaaagc aatgatagat attatcaatt aagcgaattt atatctaaaa
     1741 gggatattaa agaaaggaga tatgcttatg aagatttaca aaaaactatt tgcttatgtc
     1801 caagataaga aatatcttgg ggttttggcc ataatttttt ctgctatatc tgctctactt
     1861 acagtatatg gatattattt aatctacaaa tttctagata agttaataat taattcaaat
     1921 ttatccggtg cagagagtat agcattaaaa tctgttatta cactaacaag tggagcgata
     1981 ttttattttg tctcaggaat gttttcacac atcttgggat ttaggcttga aacaaattta
     2041 agaaaaaggg gaattgatgg cttagagaaa gcaagtttta ggttctttga cttaaatcca
     2101 tctggtcaaa taagaaagat catagatgat aatgcagcac aaactcatca ggtggtagca
     2161 cacatgattc ccgatagttc tcaggcaata atcacacccg tacttgtact tgcacttggc
     2221 tttatagtaa gtataagagt tggcataatt ttgcttgctc ttactataat tggcggctta
     2281 attttagggg caatgatggg cgagcaagaa tttatgaaga tataccaaga atccctatct
     2341 aaactaagtg ctgaaactgt tgagtacgtg agaggaatgc aagttgtaaa aatatttaaa
     2401 gcaaatgtag agtcttttaa aagcttttat aaggcgataa aagattactc aaagtatgct
     2461 tatgattatt ccctatcttg taaaaggcct tatgttttgt atcaatggtt attttttgga
     2521 ctgattgcaa ttttaattat tcctatagtt tattttatga ctagcttagc tagcgcaaag
     2581 gtgattttac ttgagcttat catgatttta tttttatcag gagttctctt tgtttcattc
     2641 atgagaatga tgtggtactc catgtatatt tctcaaggaa attatgcagt agatacttta
     2701 gaggcgcttt acgaagatat gcaaaaagac aaattagtgc atggtaatat caataatttt
     2761 aaaaactata atatagaatt tgagaatgtt agctttgctt ataatgataa agctgtcatt
     2821 gaaaatttat cctttaattt agaagaagga aagtcctacg cacttgtcgg ttcatctgga
     2881 tcaggcaaat caacagtagc aaaacttata tcaggttttt ataatgttaa taaaggaagc
     2941 ataaagatag gcgggatagc aataagtgaa tattctgacg aagccttaat taaagccatt
     3001 tcctttgttt ttcaagattc aaaattattc aagaagagca tttatgataa tgtagcttta
     3061 gctaataaag atgcgacgaa agatgacgtt atgagagcct taaaattagc aggatgcgat
     3121 ttaatattag acaaattccc agaaagagaa aatacaatca taggctcaaa aggtgtttat
     3181 ttatccggtg gagaaaaaca aagaattgca attgctagag caattttaaa ggattccaaa
     3241 attattatta tggatgaagc atcagcatct attgacccag ataacgagtt tgaattgcaa
     3301 aaagctttta aaaatcttat gaaggataaa acagttatca tgattgcaca caggctatct
     3361 acaattaaag accttgatga aattattgtc atggatagtg gaaaaattat agaaagaggg
     3421 tctgacaaag aattaatgtc aaaagataca aggtataaga gcctgcaaga gatgtttaac
     3481 agtgcgaatg aatggagggt ttcaaatgaa agagttttat aaaaaaagat ttgctcttac
     3541 agatggagga gcaagaaatt taagtaaagc aacactggct tcatttttcg tttattgtat
     3601 aaacatgctt cctgccatat tacttatgat ttttgctcag gaagttttgg aaaatatggg
     3661 caaaagcaat ggcttttata tagtattctc agttttgact ttgatagcaa tgtatatttt
     3721 gctttctatc gaatacgata aattatataa cacaacctat caagaaagtg cagatttaag
     3781 aataaggaca gcggagaatt tatcaaaatt acctctatct tacttttcta aacatgacat
     3841 ttccgacatt tcacaaacaa tcatggctga tattgaaggc atagagcatg caatgagcca
     3901 ctcaatacca aaggtgggcg gcatggtact gtttttccca ttaatatctg taatgatgct
     3961 agcgggcaat gtcaagatgg gtttagctgt aattattcca tctattttaa gctttatatt
     4021 tataccttta tctaaaaaat atcaggttaa tggacagaat agatattatg atgtcttaag
     4081 aaaaaactca gaaagctttc aagaaaatat cgaaatgcaa atggagatta aagcatataa
     4141 tttatcgaag gatattaaag atgacttata taaaaaaatg gaagatagtg agagagtaca
     4201 cttaaaggcg gaagtaacca caattttaac tttgtctata tcttcaatat ttagctttat
     4261 atctcttgct gttgtgatat ttgtcggcgt aaatctaatt attaataaag agataaattc
     4321 tctctacctt ataggatatt tactagctgc tatgaagata aaagactctt tagatgcatc
     4381 taaagagggc ttgatggaaa tattttattt atcgcccaaa atagaaagat taaaagaaat
     4441 tcaaaatcaa gatttacaag aaggcgatga ctatagctta aaaaaatttg atattgatct
     4501 aaaagatgtt gagtttgcct acaataaaga cgcaaaagtt ttaaatggtg taagttttaa
     4561 agctaagcag ggagaggtca ctgctttggt aggtgcaagt ggctgcggta aaacaactat
     4621 cttgaaactt atatcaagac tttatgatta tgacaaggga caaatcttaa tcgatgtcaa
     4681 agatataaaa gaaatatcaa cagaatctct ttttgataag gtctctatag ttttccaaga
     4741 tgtggttctc tttaatcaaa gcgttatgga aaatattaga atcggaaagc aagatgcaag
     4801 tgacgaagag gttaaaagag cagcaaaact tgcaaattgc acagatttta tagaaaaaat
     4861 ggataaaggt ttcgatacag ttattggtga gaacggagct gagctatcag gaggagaaag
     4921 acaaagatta tcaatagcca gagccttctt aaaagatgcg ccgatattga tcttagatga
     4981 gataacagca agccttgatg ttaacaacga gaaaaagatt caagagtctt taaataattt
     5041 agttaaagat aaaactgttg taatcatttc acatagaatg aaatccatag aaaatgcaga
     5101 caagatagta gttcttcaaa acggaagagt agaaagcgaa ggtaagcatg aagagctttt
     5161 acaaaaatca aaaatttaca aaaatttaat agaaaagaca aaaatggcag aagaatttat
     5221 ttattaggag gactacaatg gataataaaa aattaaaagt aaaagattta gtaagtatcg
     5281 gtgtttttgg cgtaatttat tttgccttca tgtttggagt tggtatgatg ggcttgattc
     5341 caatattgtt cttaatatac ccgacagtat tagccatagt tgcaggaact gttgttatgt
     5401 tatttatggc taaggttcaa aagccatggg cactatttat atttggtatg atatcaccac
     5461 ttgtgatgtt tgcagctggt catacctacg tagttgtggt tttatcactt atagtaatga
     5521 taatagcaga attaattaga aagattggta attataattc atttaaatac aatatgcttt
     5581 cttatgcaat cttcagcaca tggatatgta gctctttaat gcaaatgctt ttagcaaaag
     5641 aaaaatatat ggagtggtct ttgatgacga tgggaaaaga ttatgttgat gtattagaaa
     5701 agttaataac ttatcctcac atggctttag tagccttagg tgctttctta ggaggaattc
     5761 ttggagcata tataggcaag gctctattga aaaaacactt tgaaaaagca ggcatcgtat
     5821 aatgcctact ttttcttcaa atgctccctt taatcccaat ccgatctcta agatattagt
     5881 cgtatttatc acaggcttaa ctgttatgca tagcataaac atccgttttg agctggcaat
     5941 tgtttgtctt attggtattt tgctttattt gaatggatac aaaaaaacac ttttcaaatg
     6001 gattatattg tgtgggatac tttactcctt gcctaatttt atggtgttat ctgaattaaa
     6061 ccctatagtt aagatgtttt tgagtatacc tattgttatt agaatgttta ttttaccatt
     6121 tatggcagca agctttatga taaagacctc ggatgtaggc gcaataattt catcgatgga
     6181 taagcttaag atttcaaaga atgtatccat acctattgcg gttatgttta gattcttccc
     6241 atcttttaag gaggagaaga aaaacatcaa aatagctatg agagtaagag ggataaattt
     6301 taaaaaccca gtcaaatatc ttg
//
LOCUS       DAYYYC010000078         6011 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.078, whole genome shotgun sequence.
ACCESSION   DAYYYC010000078 DAYYYC010000000
VERSION     DAYYYC010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6011
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.078"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(1..552)
                     /locus_tag="ACHBV5_001999"
                     /pseudo
     CDS             complement(1..552)
                     /locus_tag="ACHBV5_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1655..2914
                     /locus_tag="ACHBV5_002000"
     CDS             1655..2914
                     /locus_tag="ACHBV5_002000"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFM9967737.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            2930..3481
                     /locus_tag="ACHBV5_002001"
     CDS             2930..3481
                     /locus_tag="ACHBV5_002001"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM9967738.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            3474..4751
                     /gene="spxR"
                     /locus_tag="ACHBV5_002002"
     CDS             3474..4751
                     /gene="spxR"
                     /locus_tag="ACHBV5_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HFM9967739.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            4767..5627
                     /locus_tag="ACHBV5_002003"
     CDS             4767..5627
                     /locus_tag="ACHBV5_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HFM9967740.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVIGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
BASE COUNT         1813 a          972 c         1356 g         1870 t
ORIGIN      
        1 tattgagatt gttaaaatct tgcgcaataa agctcatctc catctcccga ttgaaacagt
       61 cactccccgg actgtttcaa cgtcccagga cataatctca ggaagacaag aaaaatcatg
      121 tttaaagtga aaatcattga gcttacgaat aacagttgaa gttgaaatgg ccagctgatg
      181 agcaatatcg gtcatagaaa tcttctcaat caacttttgc gcaatttttt ggttgataat
      241 acgaggaatt tggtgatttt tcttgacgat agaagtttca gcgaccatca tttttgaaca
      301 gtgatagcac ttgaatcgac gctttctaag gagaattcta gtaggcatac cagttgtctc
      361 aaggtaagga atcttagacg gtttttgaaa gtcatatttc ttcaattggt ttccgcactc
      421 agggcaagat ggtgcgtcgt agtccagttt ggcgatgatt tccttgtgtg tatctttatt
      481 gatgatgtct aaaatctgga tattagggtc tttaatgtct agtaattttg tgataaaatg
      541 taattgtccc atatgaatct ttctaatgag ttgttttgtc gcttttcatt atagatctta
      601 tgggattttg tggtacgaca ggcatgtata gcaaactgaa tctggaatag cacagcatat
      661 cttctaaaat attgttataa attgatttga atttcaaaat taaattgttt gattcttatt
      721 tcaatttgtt atagtatatc tgatgtcaaa gttctcggcg aatcaaatag cgattcccaa
      781 gcctgactat cgtgaggtag cggattaaaa tggtctgggg atagaccgtt ttaagtctga
      841 cgctggaaat aagaattgtc agaagaaggg atagcgaaat cgtggctcta cgaacaggaa
      901 cgtgataata aggcgtatat agcggataag agggcctcaa actctaaagt ccaaaaaggt
      961 agtcgtaacc tatatgcgta aatcacgaga gtaattgaat tcgtactaag attttctatt
     1021 ttcactgtaa ccttttaacg tcctcatatc ttgtatacac gaggaaagat gtacgactta
     1081 tcccgtgagg tctatcacta taaagagaaa acgacagata gaagtgatcc tgagtcacgg
     1141 ttatctttaa aatagattgt ctgataggat gctagcctga aaacgtcttg ttcatgaaat
     1201 ataggacggt atgtataaaa cgcttctgtg aactgagaga agggggagaa gttcttgcta
     1261 aaatttagtt gaacagccgt attccgatat ttagataaga gatctagtct tagctcctac
     1321 tcggtttcag gggataaaaa aggggcaata gcgattcgag aaagattata ctcttcgaaa
     1381 atctcttcaa atcacgtcaa tatcgccttg ccgtacgtgt aggatactga ctacgtcagt
     1441 tccatctaca acctcaaaac agtgttttga gcaacctgcg gctagtttcc tagtgtgatc
     1501 tttgattttt attgagtatt agtaattcag ttactaactc gtcaactctg atttatccaa
     1561 taaaattgaa aaggatggaa aaaaggataa atttatgata tactttattt tgaagacctt
     1621 attagaaatc ttgaaagagt attgaaaact tagaatgaga aaaattgtta tcaatggtgg
     1681 attaccactg caaggtgaaa ttactattag tggtgctaaa aatagtgttg tggccttaat
     1741 tccagctatt atattggctg atgatgtggt gactttggat tgtgttccag atatttcgga
     1801 tgtagccagt cttgtcgaaa tcatggaatt gatgggagct actgttaagc gttatgacga
     1861 tgtcttggag attgatccaa gaggtgttca aaatattcca atgccttatg gtaaaattaa
     1921 cagtcttcgt gcatcttatt atttttatgg gagcctctta ggccgttttg gtgaagcgac
     1981 agttggtcta ccgggaggat gtgatcttgg tcctcgtccg attgacttac accttaaggc
     2041 gtttgaagct atgggtgcca ctgctagcta cgagggagat aacatgaagt tatctgctaa
     2101 agatacagga cttcatggtg caagtattta catggatacg gttagtgtgg gagcaacgat
     2161 taatacgatg attgctgcgg ttaaagcaaa tggtcgtact attattgaaa atgcagcccg
     2221 tgaacctgag attattgatg tagctactct cttgaataat atgggtgccc atatccgtgg
     2281 ggcaggaact aatatcatca ttattgatgg tgttgaaaga ttacatggga cacgtcatca
     2341 ggtgattcca gaccgcattg aagctggaac atatatatct ttagctgctg cagttggtaa
     2401 aggaattcgt ataaataatg ttctttacga acacctggaa gggtttattg ctaagttgga
     2461 agaaatggga gtgagaatga ctgtatctga agacagcatt tttgtcgagg aacagtctaa
     2521 tttgaaagca atcaatatta agacagctcc ttacccaggc tttgcaactg atttgcaaca
     2581 accgcttacc cctcttttac taagagcgaa tggtcgtggt acaattgtcg atacgattta
     2641 cgaaaaacgt gtaaatcatg tttttgaact agcaaagatg gatgcggata tttcgacaac
     2701 aaatggtcat attttgtaca cgggtggacg tgatttacgt ggggccagtg ttaaagcgac
     2761 cgacttaaga gctggggctg cactagtcat tgctgggctt atggctgaag gtaaaactga
     2821 aattaccaat atcgagttta tcttacgtgg ttattctgat attatcgaaa aattacgtaa
     2881 tttaggagcg gatattagac ttgttgagga ttaaaccgta gaggtgttta tgaatatttg
     2941 gaccaaatta gcaatgtttt ctttttttga aacggatcgc ttgtatttgc gtcctttctt
     3001 ttttagtgat agtcaggact tccgcgagat agcttcaaat ccagaaaatc ttcaatttat
     3061 tttcccaacg caggcaagtc tggaagaaag tcaatatgca ctggccaatt actttatgaa
     3121 gtcccctttg ggagtgtggg caatttgtga ccagaaaaat caacaaatga ttggttctat
     3181 taaatttgag aagttagatg aaatcaaaaa agaagctgag cttggctatt ttttgagaaa
     3241 agatgcttgg tcgcaaggat ttatgacaga ggttgttaga aaaatttgtc agctttcttt
     3301 tgaggaattt ggcttaaaac aattatctat cattacccac cttgaaaatg aagctagcca
     3361 aagagttgct cttaagtctg gatttagttt gttccgtcag tttaagggaa gtgatcgtta
     3421 cacaagaaaa atgcgggatt atcttgaatt tcggtatgta aaaggagagt tcaatgagta
     3481 agcatcagga aattctaagc tatttggagg aattaccagt aggtaaaagg gtcagtgttc
     3541 gtagcatttc gaatcatcta ggagttagtg atggaacagc ctatcgggct attaaagaag
     3601 ctgaaaaccg tggaattgtg gagacccgtc ctagaagtgg aacaattcgt gttaaatccc
     3661 agaaagttgc tatagagaga ttaacgtttg ctgaaattgc agaagtgact tcttctgagg
     3721 ttctggctgg gcaagaaggt ttagagagag aatttagtaa gttttcaatt ggtgccatga
     3781 ctgaacaaaa tatcttgtct taccttcatg atggggggct cttgattgtc ggagaccgaa
     3841 cccgtattca gttgctagcc ttggaaaatg aaaatgcagt tctggttaca gggggatttc
     3901 aggttcatga tgatgtgctt aaactggcca atcaaaaagg gattcctgtt ctaagaagta
     3961 agcatgatac ctttaccgtc gcgaccatga tcaataaagc cttgtcaaat gtccaaatca
     4021 agactgatat tctgacagtt gagaaacttt atcgccctag tcatgagtat ggttttctga
     4081 gagagacaga tacagttaaa gattatttgg acttggttcg taagaatcgt agcagccgtt
     4141 tccctgttat caatcaacat caggtcgttg ttggcgttgt aaccatgaga gacgctggtg
     4201 ataaatcacc aagcacgaca attgataagg ttatgtctcg tagtctattt ttggttggat
     4261 tatcgacaaa tattgccaat gtgagtcaac ggatgatcgc agaagacttt gaaatggtac
     4321 cagttgttcg aagcaatcaa actttgcttg gcgttgtgac gcgacgagat gtcatggaga
     4381 agatgagccg ttcccaagtt tcggctctac caactttttc tgagcagatt ggacaaaagc
     4441 tctcttatca ccatgatgaa gtagtcatta cagtggaacc ctttatgcta gaaaaaaatg
     4501 gagttttggc taatggtgta ttggcagaaa ttctgaccca catgacccaa gatttagttg
     4561 ttaatagtgg tcgcaatctc attatcgagc agatgctgat ctactttttg caggctgttc
     4621 agatagatga tatattgcgc attcaggcac ggattattca tcatacgaga cggtcagcta
     4681 taattgatta cgatatttat catggtcacc agattgtttc aaaagcaaat gtgactgtta
     4741 aaattaatta gaaactagga gaaaagatga taacattaaa atcagctcgt gaaatcgaag
     4801 ctatggacaa ggctggtgat tttctagcaa gtattcatat aggcttacgt gatttgatta
     4861 agccaggcgt agatatgtgg gaagttgaag aatatgtccg ccgtcgttgt aaagaagaaa
     4921 atttccttcc acttcagatt ggggttgacg gtgccatgat ggactatcct tatgctacct
     4981 gttgctctct taacgatgaa gtggctcacg ctttccctcg tcattatatc ttgaaagatg
     5041 gtgatttgct caaagttgat atggttttgg gaggtcccat tgctaaatct gacctgaatg
     5101 tctcaaaatt aaacttcaac aatgttgaac aaatgaaaaa atacactcag agctattctg
     5161 gtggtttagc agactcatgt tgggcttatg ctgttggtac accgtccgaa gaagtcaaaa
     5221 acttgatgga tgtaaccaaa gaagctatgt acaagggtat tgagcaagct gttattggaa
     5281 atcgtatcgg tgatatcggt gcggctattc aagaatacgc tgaaagtcgt ggttacggtg
     5341 tagtgcgtga tttggttggt catggtgttg gcccaactat gcacgaagaa ccaatggttc
     5401 ctaactatgg tattgcaggt cgtggactcc gtcttcgtga aggaatggtc ttaaccattg
     5461 aaccaatgat caatacaggc gattgggaaa ttgatacaga tatgaaaact ggttgggcgc
     5521 ataagaccat tgacggtgga ttgtcatgtc agtatgaaca ccaatttgtc attacgaaag
     5581 atggacctgt tatcttgact agccaaggtg aagaaggaac ttattaataa aaagtgaaaa
     5641 gactactgga agtttattat gaaaaaatcc agtagatctt ttcataataa aacgcattgt
     5701 atcaagtgtt aggggctgat atcatgcgtt tttctgcttt taagattttt tccaactctg
     5761 tttgtaagcg catcataaca aagggtctag gattcagggc tctcctccta tatactatta
     5821 gtaaagtaaa actaagggag gatattttag tgtcgcagtc tattgttcct gtagagattc
     5881 cacaatattg tcgttttgat tctaaaaaga gaaatggaat tctgtttaat gttcgtattg
     5941 ccaatcttaa atttaccttt tttagattag acttcctgcg aaacaaaata tggtatagta
     6001 gttccatgaa t
//
LOCUS       DAYYYC010000079         5808 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.079, whole genome shotgun sequence.
ACCESSION   DAYYYC010000079 DAYYYC010000000
VERSION     DAYYYC010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5808
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.079"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            109..1809
                     /locus_tag="ACHBV5_002004"
     CDS             109..1809
                     /locus_tag="ACHBV5_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HFM9967741.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            1802..2278
                     /gene="ilvN"
                     /locus_tag="ACHBV5_002005"
     CDS             1802..2278
                     /gene="ilvN"
                     /locus_tag="ACHBV5_002005"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HFM9967742.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            2344..3366
                     /gene="ilvC"
                     /locus_tag="ACHBV5_002006"
     CDS             2344..3366
                     /gene="ilvC"
                     /locus_tag="ACHBV5_002006"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HFM9967743.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            3473..3709
                     /locus_tag="ACHBV5_002007"
     CDS             3473..3709
                     /locus_tag="ACHBV5_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967744.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMNFEQFFKLAQI
                     SREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            3947..4303
                     /locus_tag="ACHBV5_002008"
     CDS             3947..4303
                     /locus_tag="ACHBV5_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HFM9967745.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            4353..5603
                     /gene="ilvA"
                     /locus_tag="ACHBV5_002009"
     CDS             4353..5603
                     /gene="ilvA"
                     /locus_tag="ACHBV5_002009"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HFM9967746.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
BASE COUNT         1797 a          976 c         1334 g         1701 t
ORIGIN      
        1 taaacgttaa aatagaaaat tcagaaaatt tcttctttta tcttgaaaaa ttttgaaaaa
       61 atggtatgat agtaacaagt tatttttaag aggaaagaaa ggggaacaat ggagaaaatc
      121 agtttagaat ctcctaagac ggggtcggac ctagttttgg aaacacttcg tgatttagga
      181 gttgatacca tctttggtta tcctggtggt gcggttttgc ctttttatga tgcgatatat
      241 aattttaaag gcattcgcca cattctaggg cgccatgagc aaggttgttt gcatgaagct
      301 gaaggttatg ccaaatcaac tggaaagttg ggtgttgccg tcgtcactag tggaccagga
      361 gcaacaaatg ccattacagg gattgcggat gccatgagcg atagcgttcc ccttttggtc
      421 tttacaggtc aggtggcgcg agcagggatt gggaaggatg cctttcagga ggcagacatc
      481 gtgggaatta ccatgccaat cactaagtac aattaccaag ttcgtgagac agctgatatt
      541 ccgcgtatca ttacggaagc tgtccatatc gcaactacag gccgtccagg gccagttgta
      601 attgacctac caaaagatat atctgcttta gaaacagact tcatttattc accagaagtg
      661 aatttaccaa gttatcagcc gactcttgag ccgaatgata tgcaaatcaa gaaaatcttg
      721 aagcaattgt ccaaggctaa aaagccagtc ttgttagctg gtggtggaat tagttatgct
      781 gaggctgcta cggaactaaa tgaatttgca gaacgctatc aaattccagt ggtaaccagt
      841 cttttgggac aaggaacgat tgcaacgagt cacccactct ttcttggaat gggaggcatg
      901 cacgggtcat tcgcagcaaa tattgccatg acggaagcgg actttatgat tagtattggt
      961 tctcgtttcg atgaccgttt gacggggaat cctaagactt tcgctaagaa tgctaaggtt
     1021 gcccacattg atattgaccc agctgagatt ggcaagatta tcagtgcaga cattcctgta
     1081 gttggagatg ctaagaaggc cttgcaaatg ttgctagcag aaccaacagt tcacaacaac
     1141 actgaaaagt ggattgagaa agtcactaaa gacaagaatc gtgttcgttc ttatgacaag
     1201 aaagagcgtg tggttcaacc gcaagcagtt attgaacgaa ttggtgaatt gacgaatgga
     1261 gatgccattg tggtaacaga cgttggtcaa caccaaatgt ggacagctca gtattatccc
     1321 taccaaaatg aacgtcagtt agtgacttca ggtggtttgg gaacaatggg ctttggaatt
     1381 ccagcagcaa tcggtgctaa aattgctaac ccagataagg aagtagtctt gtttgttggg
     1441 gatggtggtt tccaaatgac caaccaggag ttggctattt tgaatattta caaggtgcca
     1501 atcaaggtgg ttatgctgaa caatcattca cttggaatgg ttcgccagtg gcaggaatcc
     1561 ttctatgaag gcagaacatc agagtcggtc tttgataccc ttcctgattt ccaattgatg
     1621 gcgcaggctt atggtattaa aaactataag tttgataatc ctgagacctt ggctcaagac
     1681 cttgaagtca tcactgagga tgttcctatg ctaattgagg tagatatttc tcgtaaggaa
     1741 caggtgttac caatggtacc ggctggtaag agtaatcatg agatgttggg ggtgcagttc
     1801 catgcgtaga atgttaacag caaaactaca aaatcgttca ggagtcctca atcgctttac
     1861 aggtgtccta tctcgtcgtc aggttaatat tgaaagcatc tctgttggag caacagaaga
     1921 tccgaatgta tcgcgtatca ctattattat tgatgttgct tctcatgatg aagtggagca
     1981 aatcatcaaa cagctcaatc gtcagattga tgtgattcgc attcgagata ttacagacaa
     2041 gcctcatttg gagcgcgagg tgattttggt taagatgtca gcgccagctg agaagagagc
     2101 tgagatttta gcgattattc aacctttccg tgcaacagtg gtagacgtag cgccaagctc
     2161 gattaccatt cagatgacgg gaaatgcaga aaagagcgaa gccctattgc gagtcattcg
     2221 cccatacggt attcgcaata ttgctcgaac gggtgcaact ggatttaccc gcgattaaaa
     2281 atccaactta aatttattaa accagcctaa aaggcaataa ataatagaaa agagagaaaa
     2341 gctatgacag ttcaaatgga atatgaaaaa gatgttaaag tagcagcact tgacggtaaa
     2401 aaaatcgccg ttatcggtta tggttcacaa ggacatgcgc atgctcaaaa cttgcgtgat
     2461 tcaggtcgtg acgttattat cggtgtacgt ccaggtaaat cttttgataa agcaaaagaa
     2521 gatggatttg atacttacac agtagcagaa gctactaagt tggctgatgt tatcatgatc
     2581 ttggcgccag acgaaattca acaagaattg tacgaagcag aaatcgctcc aaacttggaa
     2641 gctggaaacg cagttggatt tgcccatggt ttcaacatcc actttgaatt tatcaaagtt
     2701 cctgcggatg tagatgtctt catgtgtgct cctaaaggac caggacactt ggtacgtcgt
     2761 acttacgaag aaggatttgg tgttccagct ctttatgcag tataccaaga tgcaacagga
     2821 aatgctaaaa acattgctat ggactggtgt aaaggtgttg gagcggctcg tgtaggtctt
     2881 cttgaaacaa cttacaaaga agaaactgaa gaagatttgt ttggtgaaca agctgtactt
     2941 tgtggtggtt tgactgccct tatcgaagca ggtttcgaag tcttgacaga agcaggttac
     3001 gctccagaat tggcttactt tgaagttctt cacgaaatga aattgatcgt tgacttgatc
     3061 tacgaaggtg gattcaagaa aatgcgtcaa tctatttcaa acactgctga atacggtgac
     3121 tatgtatcag gtccacgtgt aatcactgaa caagttaaag aaaatatgaa ggctgtcttg
     3181 gcagacatcc aaaatggtaa atttgcaaat gactttgtaa atgactataa agctggacgt
     3241 ccaaaattga ctgcttaccg tgaacaagca gctaaccttg aaattgaaaa agttggtgca
     3301 gaattgcgta aagcaatgcc attcgttggt aaaaacgacg atgatgcatt caaaatctat
     3361 aactaattag aaatatatag cgctggagat gattttatga aaaagattat gagaaaaact
     3421 gcatcgttat tattggttct agttgtataa tgtaattaca ccgtcggtaa tagtgctagc
     3481 agaccaaaat aaagcagatt ggtcgtatga tgaaaatgct gtaattaaca tttatgatga
     3541 tgctaatttt gaagatggta ggttgcatat gaactttgaa caattcttca aattggcaca
     3601 aatatctaga gaagaaggtc ttgaaattca ttctccgttt gagagagctg gtgcgactaa
     3661 atctgctcgt tatatagcga aatggatttt gagaaataaa aaacattaac aaatatagtt
     3721 ggtaaatcat taggacctaa atcagctgtt agattcggag aagctttatc ctatattgaa
     3781 ggtcctcttc gcagaataaa tgagacgata gatggcggtt tatatcaaat agagcaaatt
     3841 attgcatctg gattgaaaga atcgggttta aatgactgga ctgcgaaaac tttagcttca
     3901 gctattcgtg ggatattaga tgtacttatt taggggttga aatcatatga atattaccaa
     3961 tttgttttct atcaagacag gatgtgatga aactgatagg caactgcaaa aactattttt
     4021 tcagttggat ttacaattgg gagaattgac agatcaacta agaaaattag attctaattt
     4081 tgttcctcgt agtcaatttg tagacacgtt ggatttgaat gatgtagaat ataaagaaat
     4141 tttaaactat tttatcttcc atcgtaatga tagtgaagaa agtttggtag aatggttata
     4201 tgattggatt tccacaaatc gttatgaact tcctaaagag ttttcgattc gtatggctca
     4261 taaataccat gaaagtgtta ctgaagtttt cggagatgaa taactaaaaa acagtcatta
     4321 gtgactgttt tttatagaaa aagaggtttt atatgttaag ttcaaaagat ataatcaagg
     4381 ctcacaaggt cttgaacggt gtggttgtga atactccact ggattacgat cattatttat
     4441 cggagaagta tggtgctaag atttatttga aaaaagaaaa tgcccagcgt gttcgctcct
     4501 ttaaaattcg tggtgcctat tatgccattt cccagctcag caaggaagaa cgtgaacgtg
     4561 gggtagtctg cgcttctgcg ggaaatcatg cgcagggagt agcctatact tgtaatgaaa
     4621 tgaaaattcc tgctactatc tttatgccca ttactacgcc acaacaaaag attggtcagg
     4681 ttcgcttttt tggtggggat tttgtaacta ttaaactagt tggagatacc tttgatgcct
     4741 cagccaaagc agctcaagaa tttacagtct ctgaaaatcg tacctttatt gatccttttg
     4801 atgatgctca tgttcaagca ggtcaaggaa cagttgctta tgagatttta gaagaagctc
     4861 gaaaagaatc gattgatttt gatgctgtct tggttcctgt tggtggtggc ggtctcattg
     4921 ccggggtttc tacctatatc aaggaaacaa gtccagagat tgaggttatc ggagtagagg
     4981 cgaatggagc gcgttccatg aaagctgcct ttgaggctgg aggtccagtc aaactcaagg
     5041 aaattgataa atttgcggat gggattgctg tgcaaaaggt aggtcagttg acctatgaag
     5101 caactcgtca acatattcaa actttggtag gtgtcgatga gggattgatt tctgaaacct
     5161 tgattgacct ttactctaag caagggatag tcgcagaacc tgctggagca gctagtatcg
     5221 cctctttaga ggttttagct gaatatatta aggggaaaac catttgttgt atcatttctg
     5281 gaggaaataa tgatatcaac cgtatgccag aaatggaaga gcgtgccttg atttatgatg
     5341 gtatcaaaca ttactttgtg gtcaatttcc cacaacgtcc aggagctttg cgtgagtttg
     5401 taaatgatat cctggggcca aatgatgata tcacacgttt tgagtatatc aaacgagcta
     5461 gcaagggaac aggcccagta ttaattggga tcgctttagc agataagcat gattatgcag
     5521 gtttgattcg tagaatggaa ggttttgatc cagcttatat taacttaaat ggtaatgaaa
     5581 cgctttataa tatgcttgtc tgaggactaa taaaaaaata tcatattatt tgtacaactg
     5641 atgtatatgt gctataatga agatgaagaa aggggacgat tcctatggtt ttagaaaact
     5701 tatcgtgcaa ttcttacttc tgttcattat agcacttatg atgtttggct cagatttcca
     5761 tccttcattt tgatttccta tctattgaca agcatagtca cactgtct
//
LOCUS       DAYYYC010000080         5801 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.080, whole genome shotgun sequence.
ACCESSION   DAYYYC010000080 DAYYYC010000000
VERSION     DAYYYC010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5801
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.080"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            1..160
                     /locus_tag="ACHBV5_002010"
                     /pseudo
     CDS             1..160
                     /locus_tag="ACHBV5_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            221..1197
                     /locus_tag="ACHBV5_002011"
                     /pseudo
     CDS             221..1197
                     /locus_tag="ACHBV5_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            1374..2381
                     /gene="gap"
                     /locus_tag="ACHBV5_002012"
     CDS             1374..2381
                     /gene="gap"
                     /locus_tag="ACHBV5_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFM9967747.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2448..3323)
                     /locus_tag="ACHBV5_002013"
     CDS             complement(2448..3323)
                     /locus_tag="ACHBV5_002013"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFM9967748.1"
                     /translation="MQFTFTLPASLPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVHWKEIVNPGDVCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLA
                     HCKLKTGRTHQIRVHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTF
                     TTLSNTFEKELKKNG"
     gene            3410..5605
                     /gene="pbp2a"
                     /locus_tag="ACHBV5_002014"
     CDS             3410..5605
                     /gene="pbp2a"
                     /locus_tag="ACHBV5_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HFM9967749.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
BASE COUNT         1755 a         1058 c         1263 g         1725 t
ORIGIN      
        1 gtgaagagtt tgggcataaa cttttacctc ttcctcccta ctcacctgag tacaatctat
       61 tgagaaaaca tgggctcata tcaaaaagca cctcaaaaag gtattaccaa gttgcaatac
      121 cttttacgag gcttttttat cctgctcttg tttcaattga ctatagttca cggatacagt
      181 tgggaaagaa gctattaaat atttggagag tccttttggg atgaacatgt caaatattac
      241 tatagatggg caagaaaaga tgggcaagaa atggatctga gtcaaacgat gccttcttat
      301 gctcaagtag tgagtcttta tgatgataca agtatctctg ttagtaataa tgagacggac
      361 aaagtgttgg ctggctccct ctatactgat acaaatgaac agggattaac gattccaagc
      421 agtttactaa aaaattggaa tgaacagaca ggaaaaaatt tgacagctaa tgatcttatt
      481 ggcaaatcag tctcagccag cattgtagaa agtgctgccg aaactagtaa gattgctcaa
      541 tttcaaacga agattgtacg tgtaatcaat gatgaagatg acatggagga cagcaacagt
      601 ttcatgctgt ctcatcaaat ggaaacgatt ttgaaagagg ctggatttac gaaagctgta
      661 tcttatttta tcttggaact caaagatcca tcacagacaa aagtagtaac agaagaatta
      721 cagaaaaata agaagtatac tgtgctttct caacagagag ttcttgatat tgtgattacc
      781 tttattcgtg ttattcaggg attattgatt gtgctttcat cacaagctat tgtggtagca
      841 gcggttatga ttggtatcat tatttacatc aatatcatgc aacgttccaa ggaaataggt
      901 gtcatgaaag cagttggtta tcagaatcgt ggtgtcaaag gaatttttat ttacgaggct
      961 atctggattg taggcatcgc cttgctgctg gcatttttgg ttgcacaagg ggtgggaagt
     1021 ttggcgaatg cgattgtaag tcacttttac ccatccatca ctaaggtttt tgaattaaat
     1081 cttttatctg ttttaggaac tctagttttc gctctattac ttggttatgt ctcagcctac
     1141 ttcccggcgc gtaagattag taaaatggat cctgtagaat cgttacgcta tgaataataa
     1201 gggattcctt gatttacagt cttaaaaaga aactcacata gaaaaacaat ggccatactt
     1261 gcaattcaac tcaaatagtt gtataatagg tttgttgaaa ggtgatttgt agtgattcaa
     1321 gttactcttt tcacaataaa aatttcatga ttttcataag gaggaaatca ctaatggtag
     1381 ttaaagttgg tattaacggt ttcggacgta tcggtcgtct tgctttccgt cgtatccaaa
     1441 acgtagaagg tgttgaagtt acacgcatca acgaccttac agatccagtt atgcttgcac
     1501 acttgttgaa atacgacaca actcaaggtc gtttcgacgg tactgttgaa gttaaagaag
     1561 gtggattcga agttaacggt aaattcgtta aagtttctgc tgaacgtgat ccagagcaaa
     1621 tcgactgggc tactgacggt gtagaaatcg ttcttgaagc tactggtttc tttgctaaga
     1681 aagaagcagc tgaaaaacac cttaaaggtg gagctaaaaa agttgttatc actgctcctg
     1741 gtggaaacga cgttaaaaca gttgtattca acactaacca cgacgttctt gacggtactg
     1801 aaacagttat ctcaggtgct tcatgtacta caaactgctt ggctccaatg gctaaagctc
     1861 ttcaagataa ctttggtgtt gttgaaggat tgatgactac tatccacgct tacactggtg
     1921 accaaatgat ccttgacgga ccacaccgtg gtggtgacct tcgccgtgct cgcgctggtg
     1981 ctgcaaacat cgttcctaac tcaactggtg ctgctaaagc tatcggtctt gtaatcccag
     2041 aattgaacgg taaacttgac ggatctgcac aacgcgttcc aactccaact ggatcagtta
     2101 ctgaattggt agcagttctt gaaaagaacg ttactgttga tgaagtgaac gcagctatga
     2161 aagcagcttc aaacgaatca tacggttaca cagaagatcc aatcgtatct tcagatatcg
     2221 taggtatgtc ttacggttca ttgtttgacg caactcaaac taaagttctt gacgttgacg
     2281 gtaaacaatt ggttaaagtt gtatcatggt acgacaacga aatgtcatac actgcacaac
     2341 ttgttcgtac tcttgaatac ttcgcaaaaa ttgctaaata attcttgagt tgatagaaag
     2401 caaggctttg tggtcttgct ttttatatgg aaaaatggat gacacgatca tccattcttt
     2461 tttaattctt tttcaaatgt atttgaaagg gtagtgaaag ttagcttctc taaagtaagt
     2521 gggtgggtaa aggaaagtcg gaaggcatga agcataagcc ggcttgtctt tgatttacta
     2581 ttatagagag ggtctcccag gataggaaga ttatgatgcg aaaggtgcac acgaatctga
     2641 tgggttcgcc ctgtctttag cttgcaatga gccaaggaag tcttgtttga gaattgcttt
     2701 aatctgctta catgcgtttc agcatattgc ccattttttg catcaactat tctttttcta
     2761 cgatcatggc gatcacgtcc aattttgtct ctgaaaacaa gttcttttct gttgatattt
     2821 ccatcaacta gagcccaata ttctctagaa atctcttttt tctccaataa gcgattgaga
     2881 atgggcagga taaaaggatt tttggcaaag agaactaagc cactggtttc catgtccaga
     2941 cgatgaacga catagcaggt ttggccaaca taggtactga catggttaag aagggcaatt
     3001 tcgtttggtt gattaccatg cgttttcatc ccctctggtt tgtttacaat aatcaagtgt
     3061 tgatcttgat aaacttcctg cactaagtct gggttgcccc aagggatcgt cttttgggaa
     3121 taatcttcct cgtcaaaagt caactggcaa acatctccag gatttacgat ttccttccag
     3181 tggacttctt cttgatttat caaaatatgt ttcttgattc tcaaaaaatg acggattttt
     3241 ctagggatga ggagttgttc ctcaagtaat tgctttactg tcatttgagg tagagaggcg
     3301 ggtaatgtaa atgtgaattg catacagata ttgtaacaaa aaaagcccta tttggatagg
     3361 aaatagctaa attcttgtct tcctatgatg aagatgataa aataaacgca tgaaattaga
     3421 taaattattt gagaaatttc tttctctttt taaaaaagaa acaagtgaac tagaggactc
     3481 tgattctact atcttacgtc gctctcgtag tgatcgaaaa aaattagccc aagtaggtcc
     3541 gattcgaaaa ttctggcgtc gttatcatct aacaaagatt atccttatac taggtttgag
     3601 tgcaggcttg ctagttggaa tctatttgtt tgctgtagcc aagtcgacca atgtcaatga
     3661 tttgcaaaat gccttgaaaa ctcggactct tatttttgac cgtgaagaaa aagaggctgg
     3721 tgccttgtct ggtcaaaagg gaacctatgt tgagctgact gacatcagta aaaacttgca
     3781 gaatgctgtt attgcgacag aagaccgttc tttctataaa aatgacggga ttaactatgg
     3841 ccgttttttc ttggctattg tcactgctgg acgttcaggt ggtggctcta ccattaccca
     3901 acagctggct aaaaacgcct atttatcgca ggatcaaact gttgagagaa aagcgaaaga
     3961 atttttcctt gccttagaat taagcaaaaa atatagtaag gagcaaattc taaccatgta
     4021 ccttaacaac gcttattttg gaaatggtgt gtggggtgta gaagatgcga gtaagaaata
     4081 ctttggagtt tctgcatcag aagtgagtct ggatcaagct gcgactctgg cagggatgct
     4141 caaggggccg gaactgtata atcccttgaa ttccgtagaa gattctacta atcggcgcga
     4201 tactgtcttg cagaatatgg ttgcagcagg atatattgat aaaaaccaag aaaccgaagc
     4261 tgctgaagtt gatatgactt cgcaattgca cgataagtat gaaggaaaaa tctcagatta
     4321 ccgttacccc tcttattttg atgcggtggt taatgaagct gtttccaagt ataatctaac
     4381 agaggaagag attgtcaata atggctaccg catttacaca gagctggacc aaaactacca
     4441 agcaaatatg cagattgttt atgaaaacac atcgctattt ccgagggcag aggatggaac
     4501 gtttgctcaa tcaggaagtg tagctctcga accgaaaaca gggggagttc gtggagttgt
     4561 cggtcaagtt gctgacaatg ataaaactgg attccggaat ttcaactatg caacccaatc
     4621 aaagcgtagt cctggttcta caattaagcc tttagttgtt tatacgccag cagttgaagc
     4681 aggctgggct ttgaataagc agttggataa ccataccatg cagtatgaca gctataaggt
     4741 tgataactat gcagggatca aaacgagtcg agaagttcct atgtatcaag ccttggcaga
     4801 atcgcttaat ctacctgctg ttgccactgt taatgatttg ggtgtcgata aggcttttga
     4861 ggcaggcgaa aaattcggac tcaacatgga aaaggtcgac cgtgttcttg gtgtcgcctt
     4921 gggaagcggt gttgaaacca accctcttca aatggctcaa gcatacgctg cctttgcaaa
     4981 tgaaggttta atgcctgaag ctcattttat tagtagaatt gaaaatgcta gtggacaagt
     5041 tattgcgagt cataaaaatt cacaaaaacg ggtgattgat aagtctgtag ctgacaagat
     5101 gaccagtatg atgttgggga ctttcaccaa cggtaccggt attagttcat cgcctgcaga
     5161 ctatattatg gcagggaaaa ctggaacaac tgaagcagtt ttcaatccgg agtacacaag
     5221 tgaccagtgg gtaattggtt atactccgga tgtagtgatt agccactggc ttggctttcc
     5281 gaccactgat gaaaatcact atctagctgg ctctacttca aacggtgcag ctcatgtctt
     5341 tagaaacatt gccaatacca ttttacctta tacgccagga agtaccttta cggttgaaaa
     5401 tgcttataag caaaatggaa ttgcaccagc caatacaaaa agacaagtac aaaccaatga
     5461 taatagccag acagatgata atttgtctga tattcgaggg cgtgcgcaaa gtctagtaga
     5521 tgaggctagc cgggctatct cagatgcgaa gattaaggaa aaggctcaaa caatatggga
     5581 ttcgatagtc aatctatttc gctaagatgc tgtcaatcga aagtgattat gtccccaaaa
     5641 aatggagagt ttgagggcaa ttattttgat ttcatttgac acgaggagcc cttgaagctg
     5701 ttttgttagc taaaccaagg ctagtcttag ccttggctcg ccagcctaac agctccaagc
     5761 ctcttatcaa atgaaatgct tgtcttacac tcctcacttt c
//
LOCUS       DAYYYC010000081         5478 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.081, whole genome shotgun sequence.
ACCESSION   DAYYYC010000081 DAYYYC010000000
VERSION     DAYYYC010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5478
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.081"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            503..724
                     /locus_tag="ACHBV5_002015"
                     /pseudo
     CDS             503..724
                     /locus_tag="ACHBV5_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            complement(1011..1493)
                     /locus_tag="ACHBV5_002016"
     CDS             complement(1011..1493)
                     /locus_tag="ACHBV5_002016"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFM9967750.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(1588..3072)
                     /locus_tag="ACHBV5_002017"
     CDS             complement(1588..3072)
                     /locus_tag="ACHBV5_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFM9967751.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQLAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3225..4832
                     /locus_tag="ACHBV5_002018"
     CDS             3225..4832
                     /locus_tag="ACHBV5_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFM9967752.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDELIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            4997..5164
                     /locus_tag="ACHBV5_002019"
     CDS             4997..5164
                     /locus_tag="ACHBV5_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HFM9967753.1"
                     /translation="MKKRILSAGLTFTSALLLAACDQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(5157..>5478)
                     /locus_tag="ACHBV5_002020"
     CDS             complement(5157..>5478)
                     /locus_tag="ACHBV5_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM9967754.1"
                     /translation="NGELIAPMTYEEMMTSDFFEVWFQKFFLPTLTTPSVIIMDNARF
                     HRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSC
                     SCFN"
BASE COUNT         1622 a         1031 c         1245 g         1580 t
ORIGIN      
        1 atcgctctga atatcaaaaa agaaaggaca aaatttgtcc tttctcgagc ttagctgact
       61 tcaacccact acagttgaca aagagccaaa aaaactggtt ccttttgagg tacgacgggc
      121 atgtcgtata gtaggttgaa actagaatag tacacatcta cttctaaaac atttttagaa
      181 atcgatttga ctgtcctgat cgatttgtcc tgttcttatt tcattttact atatatctga
      241 ggtgtaagtc ctcggtgggc acctgttacc ggtgaaccca atagcgattc ccaagcctga
      301 ctatcgtgag gtagcggatt aaaacggtct ggggatagac cgttttaagt ctgacgctgg
      361 aaataagaat cgtcagagga agggatagcg aactcgtggc tctacgaaca ggaacgtgat
      421 agtaaggcgt atatagcgga taagggggcc tcaaactcta aagtccaaaa aggtagtcgt
      481 aacctatatg cgtaaatcac gagagcaact gaatttgtcc attcgaggat ggataaacta
      541 tttttcattg ggaaatatga aaagtatagt caccagcata gatgagcgtt tgcatactcg
      601 cctacgagtg attatctgga agcaatggaa gaagaaatcg agacgattat ggggattgct
      661 taagttaggg gttcctaaat ggatagcaga taaggtatct ggctggggcg accactatca
      721 attatagtaa aatgaaataa gaatagaaca aatcgatcag gatagtcaaa tcgatttcta
      781 acaatgtttt agaagcagag gtgaactatt ctagtttcaa tccactatag tagctcagaa
      841 gtcggtactt aaacgtgcta tatcaaaacc agtccttgaa aaacgtggat tggtttcgtg
      901 tttggattat taccttgaac gacatgcgtt aaaaagttag ttgaaccgcc gtatgccgaa
      961 cggtacgtac ggtggtgtga gaggggctag agattatccc ctactcgatt ttaaatcaca
     1021 tgacgttcaa aggcatcatc tgaaatccct tgttccaaga tgagttttgc ccattcttta
     1081 gcagagaaga ggctgtggtc cttgtagttt ccgcaagatt cgatggttgt ccctgggaca
     1141 tcttcccaag tagtagtttc agcgatttcc ttgagcgaat ccttgataac agctgcgatt
     1201 ttagcactgg tgtgacgtcc ccacataatc atgtggaagc ctgtgcggca accaaatggt
     1261 gaacagtcaa tcatgccgtc aatgcgggta cggatgagtt tggctaagag gtgctcgata
     1321 gtgtgaaggc cggcagtagg gatagagtct tcgtttggtt gcaccaagcg aatatcataa
     1381 ttggagatga tgtctccttt tggtcctgtt tcttccccaa tcaagcgaac atagggtgct
     1441 ttgacaatgg tgtggtcaag ttcaaaactt tcgacaataa cttcttttga catggtaaat
     1501 cctttcagtt ttcttctctc attatatcat aaaggttgct cctgagacag agagaaaacc
     1561 tctccgaggc tggagaggtt gaaatcttta cttacgatat aagcggtcgt attggtagta
     1621 tgggtcaaag gttacgttga tacccagttt acgaaggaca ttcttgtctt catcagtcaa
     1681 gatgatggtt gagtgggctt cgcttccttt gaggttgccg agttcttcca tagcgcgggc
     1741 agcatcagga ttttctgtag ctgtgatagc aagtgcaatc aggatttcat ttgaatgaag
     1801 gcgtggattg cggctaccga gatgatcgat tttaagacct tggattggct taacaacttc
     1861 aggctcgatt agttttactt ctttagcgat gtcagctgat tttttgatgg cgttgatcaa
     1921 ggcagcggct gtaggcccaa agagttctga gttcttacca gtgacgattt ccccatttgg
     1981 caattcaaag gctagggctg gtccaccagt ttcttctgct ttttggcgcg caacgacagc
     2041 aaccttacgg tctgcaggtg tgataccgag gtcgttcatg agcaactcaa ttttcttgac
     2101 ggcagcttcg ccaacttttt cagctttgaa gtcaagaact gtttgatagt aacggcggat
     2161 gatttcttgt ttagaagctt cgacagcagc ctcgtcatct gtaatagcga aaccaaccat
     2221 gttgacaccc atatctgtcg gtgaagcgta tggtgatttt ccgagaatac gttccaacat
     2281 gcgcttgagc actgggaaga tttcgatatc acggttgtag ttgacagtgg tttctccata
     2341 ggtttgaaga tggaaggggt caatcatgtt gacatcatca aggtcagctg tggcagcttc
     2401 ataagccaag ttaactggat gatgaagggg aagattccaa acagggaagg tttcaaattt
     2461 agcgtagcca gacttgatgc cattgatttg gtcgtggtac atattggaca tacacgttgc
     2521 caattttcca gaaccgggtc caggagcggt tacgacaatc aagttgcgac tggttttgat
     2581 gtagtcgttt ttgcccatgc cttctgggga aatgatgtga tccatatccg tcggatatcc
     2641 tttgattgga taatgaagat aagaatcaat tccgtttttc tcaagttggt tgcggaaggc
     2701 atctgcagcg agttggccag cgtattgtgt aatgacaacg gaaccaacaa aaatccctaa
     2761 ttcattgaat ttgtcaatca aacgaagaac ttcttggtca taagaaatgc ctaagtcgcc
     2821 acgtgctttg gaatgttcaa tgttgctagc attaatggca atcacaacct caacctgctc
     2881 tttcaattct tgcaagagct tgattttgtt gtcaggttca taaccaggaa ggacacgagc
     2941 agcgtggaaa tcttctaaca ttttaccgcc aaactctaag tagagcttgc cgtcaaattg
     3001 gttaatgcgc tctaagatgt ggtcgcgttg taaattcaaa tactgttcag aactaaaagc
     3061 ttgttttttc atttttttac ctctggattc tattataata aaaaattgga agttaggaaa
     3121 ctacggagct aaaaaagaaa ttaaaaagat taagcaaacg cttgcacaaa attttaaaaa
     3181 gtgctatcat atactataga ttattaaaat aatgaggtaa acagatgcaa gaaaaatggt
     3241 ggcataatgc cgtagtctat caagtctatc caaagagttt tatggatagt aatggagatg
     3301 gagttggtga tttgccaggt attaccagta agttggacta tctagctaag ctaggaatca
     3361 cagcgatttg gctttctccc gtttatgaca gccctatgga tgataatggc tatgatattg
     3421 ctgattatca agcgattgcg gctatttttg gaaccatgga ggacatggat gaactgattg
     3481 cagaagctaa gaagcgtgat atccgtatca tcatggactt ggtggtcaat catacctcgg
     3541 atgagcatgc ctggtttgta gaggcctgtg aaaatcctaa tagccctgag cgagactact
     3601 atatctggcg ggatgagcct aacgatttag attctatctt tagtgggtct gcttgggaat
     3661 acgatgaaaa gtcaggtcaa tactatctcc actttttcag caagaaacag ccggatctca
     3721 actgggaaaa tgaaaaactt cgccagaaaa tttatgagat gatgaacttc tggattgata
     3781 agggtattgg tggtttccgt atggatgtta ttgacatgat tggcaaaatt cctgacgaga
     3841 aggtagtcaa taatggtcct atgctccatc cctatctcaa ggaaatgaat caggcgacct
     3901 ttggagataa ggatctcttg acagtagggg agacttgggg agcaacgcca gagattgcca
     3961 aactctactc tgatccaaag gggcaagaat tgtctatggt cttccagttt gaacatatcg
     4021 gtcttcagta tcaggaaggt caacctaaat ggcactatca aaaagagctg aatatcgcta
     4081 agttaaaaga aatcttcaac aaatggcaga cagagttagg agttgaggac ggctggaatt
     4141 ccctcttctg gaacaaccat gacctccctc gtattgtctc aatctgggga aatgaccaag
     4201 aataccgcga aaaatctgcc aaagcctttg caatcttact tcatctcatg agaggaactc
     4261 cttatatcta ccaaggtgag gagattggga tgaccaacta tccgtttgaa acactggatc
     4321 aagtagaaga tattgaatct ctcaactatg cgcgtgaggc tcttgaaaaa ggtgttccga
     4381 ttgaagaaat catggacagt atccgtgtta ttggacgtga caatgcccgt acccctatgc
     4441 aatgggacga gagcaaaaac gctggtttct caacaggtca accttggttg gcagttaatc
     4501 caaattacga gatgatcaac gtccaagaag cgctggcaaa tccagattct attttctata
     4561 cctatcagaa actggtccaa attcgcaagg agaatagctg gctaattcga gctgactttg
     4621 aattgcttga tacggctgat aaggtctttg cttatatacg taaggatggc gaccgtcgct
     4681 tcctagttgt ggctaacttg tccaatgaag agcaagactt gacagtagaa ggaaaagtca
     4741 aatctgtctt gattgaaaac accctagctc aagaagtctt tgaaaaacaa atcttagttc
     4801 catgggatgc tttctgtgtg gaattactat aaatattttt tgcagaaaaa tttaaaattg
     4861 aaatcgtata aaaacaaggg aggactgtat aaaaggcaga aatcctttgt tttttataac
     4921 caaggtttat aaaccttcat tctcgaaatt caattaactt tacaaattcc cactattaag
     4981 gagaaagaag acgaacataa agaagcgtat ccttagtgca ggcctgactt ttacatctgc
     5041 tttgctttta gctgcttgcg accaatcagg ttcagataca aaaacttact catcaacctt
     5101 tagtggaaat ccaactacat ttaactatct attagactat tacgctgata atatagtcaa
     5161 ttgaaacaag aacaagacaa aagagcctca taaaaggtat tgcaacttgg taataccttt
     5221 ttgaggtgct ttttgatatg agcccatgtt ttctcaatag gattgtactc aggtgagtag
     5281 ggaggaagag gtaaaagttt atgcccaaac tcttcgcata aaagttctag cttccccatt
     5341 ctatggaatc ttgcattatc cataataata accgatggtg tggttaatgt tggtaagaaa
     5401 aacttctgaa accatacttc aaaaaagtcg ctcgtcatca tctcttcgta agtcattgga
     5461 gcgattaatt caccattt
//
LOCUS       DAYYYC010000082         4792 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.082, whole genome shotgun sequence.
ACCESSION   DAYYYC010000082 DAYYYC010000000
VERSION     DAYYYC010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4792
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.082"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            97..1642
                     /locus_tag="ACHBV5_002021"
     rRNA            97..1642
                     /locus_tag="ACHBV5_002021"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1694..1766
                     /locus_tag="ACHBV5_002022"
     tRNA            1694..1766
                     /locus_tag="ACHBV5_002022"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1727..1729,aa:Ala,seq:tgc)
     gene            1891..4792
                     /locus_tag="ACHBV5_002023"
     rRNA            1891..4792
                     /locus_tag="ACHBV5_002023"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1333 a          984 c         1423 g         1052 t
ORIGIN      
        1 gaaccaatgt gcagggcgct acaacataag ttgtagtact gaacaatgaa aaaacaataa
       61 atctgtcagt gacagaaatg agtgagaact caaactttta atgagagttt gatcctggct
      121 caggacgaac gctggcggcg tgcctaatac atgcaagtag aacgctgaag gaggagcttg
      181 cttctctgga tgagttgcga acgggtgagt aacgcgtagg taacctgcct ggtagcgggg
      241 gataactatt ggaaacgata gctaataccg cataagagtg gatgttgcat gacatttgct
      301 taaaaggtgc acttgcatca ctaccagatg gacctgcgtt gtattagcta gttggtgggg
      361 taagggctca ccaaggcgac gatacatagc cgacctgaga gggtgatcgg ccacactggg
      421 actgagacac ggcccagact cctacgggag gcagcagtag ggaatcttcg gcaatggacg
      481 gaagtctgac cgagcaacgc cgcgtgagtg aagaaggttt tcggatcgta aagctctgtt
      541 gtaagagaag aacgagtgtg agagtggaaa gttcacactg tgacggtatc ttaccagaaa
      601 gggacggcta actacgtgcc agcagccgcg gtaatacgta ggtcccgagc gttgtccgga
      661 tttattgggc gtaaagcgag cgcaggcggt tagataagtc tgaagttaaa ggctgtggct
      721 taaccatagt aggctttgga aactgtttaa cttgagtgca agaggggaga gtggaattcc
      781 atgtgtagcg gtgaaatgcg tagatatatg gaggaacacc ggtggcgaaa gcggctctct
      841 ggcttgtaac tgacgctgag gctcgaaagc gtggggagca aacaggatta gataccctgg
      901 tagtccacgc tgtaaacgat gagtgctagg tgttagaccc tttccggggt ttagtgccgt
      961 agctaacgca ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa
     1021 ttgacggggg cccgcacaag cggtggagca tgtggtttaa ttcgaagcaa cgcgaagaac
     1081 cttaccaggt cttgacatcc ctctgaccgc tctagagata gagctttcct tcgggacaga
     1141 ggtgacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg
     1201 caacgagcgc aacccctatt gttagttgcc atcatttagt tgggcactct agcgagactg
     1261 ccggtaataa accggaggaa ggtggggatg acgtcaaatc atcatgcccc ttatgacctg
     1321 ggctacacac gtgctacaat ggctggtaca acgagtcgca agccggtgac ggcaagctaa
     1381 tctcttaaag ccagtctcag ttcggattgt aggctgcaac tcgcctacat gaagtcggaa
     1441 tcgctagtaa tcgcggatca gcacgccgcg gtgaatacgt tcccgggcct tgtacacacc
     1501 gcccgtcaca ccacgagagt ttgtaacacc cgaagtcggt gaggtaaccg taaggagcca
     1561 gccgcctaag gtgggataga tgattggggt gaagtcgtaa caaggtagcc gtatcggaag
     1621 gtgcggctgg atcacctcct ttctaaggat aaggaactgc gcattggtct tgtttagtct
     1681 tgagaggtct tgtggggcct tagctcagct gggagagcgc ctgctttgca cgcaggaggt
     1741 cagcggttcg atcccgctag gctccattgg tgagagatca ccaagtaatg cacattgaaa
     1801 attgaatatc tatatcaaat agtaacaaga aaataaaccg aaaacgctgt agtattaata
     1861 agagtttatg actgaaaggt cagaaaataa ggttaagtta ataagggcgc acggtggatg
     1921 ccttggcact aggagccgac gaaggacgtg acaaacgacg atatgccttg ggtagctgta
     1981 agtaagcgat gatccaggga tttccgaatg ggggaaccca acaggtagta cctgttaccc
     2041 acatctgtta aggatgtgag gaggaagacg cagtgaactg aaacatctaa gtagctgcag
     2101 gaagagaaag caaaagcgat tgccttagta gcggcgagcg aaacggcaga agggcaaacc
     2161 gaagagttta ctcttcgggg ttgtaggact gcaatgtgga ctcaaagatt atagaagaat
     2221 gatttgggaa gatcagccaa agagagtaat agcctcgtat ttaaaatagt ctttgtacct
     2281 agcagtatcc tgagtacggc gggacacgtg aaatcccgtc ggaatctggg aggaccatct
     2341 cccaacccta aatactccct agtgaccgat agtgaaccag taccgtgagg gaaaggtgaa
     2401 aagcaccccg ggaggggagt gaaatagaac ctgaaaccgt gtgcctacaa caagttcgag
     2461 cccgttaatg ggtgagagcg tgccttttgt agaatgaacc ggcgagttac gttatgatgc
     2521 gaggttaagt tgaagagacg gagccgtagg gaaaccgagt ctgaataggg cgccttagta
     2581 tcatgacgta gacccgaaac catgtgacct acccatgagc aggttgaagg tgcggtaaga
     2641 cgcactggag gaccgaacca gggcacgttg aaaagtgctt ggatgacttg tgggtagcgg
     2701 agaaattcca aacgaacttg gagatagctg gttctctccg aaatagcttt agggctagcg
     2761 tcgacattag agattcttgg aggtagagca ctgtttgggt gaggggtcca tcccggatta
     2821 ccaatctcag ataaactccg aatgccaatg aattatggtc ggcagtcaga ctgcgagtgc
     2881 taagatccgt agtcgaaagg gaaacagccc agaccaccag ctaaggtccc aaaataattg
     2941 ttaagtggaa aaggatgtgg ggttgcacag acaactagga tgttagctta gaagcagcta
     3001 ttcattcaaa gagtgcgtaa tagctcacta gtcgagtgac cctgcgccga aaatgtaccg
     3061 gggctaaaac aatttaccga agctgtggat acctttatag gtatggtagg agagcgttct
     3121 atgtgtgatg aaggtatacc gtgaggagtg ctggaacgca tagaagtgag aatgccggta
     3181 tgagtagcga aagacaggtg agaatcctgt ccaccgtaag actaaggttt ccaggggaag
     3241 gctcgtccgc cctgggttag tcgggaccta aggagagacc gaaaggtgta tccgatggac
     3301 aacaggttga tattcctgta ctagagtatg tagtgatgga gggacgcagt aggctaacta
     3361 aagcagacga ttggaagagt ctgtctaagc agtgaggtgt gaattgagtc aaatgcttaa
     3421 ttctataaca ttgagctgtg atggggagcg aagtttagta gcgaagttag tgacgtcaca
     3481 ctgccaagaa aagcttctag cgtttaaaca tactctaccc gtaccgcaaa ccgacacagg
     3541 tagtcgaggc gagtagcctc aggtgagcga gagaactctc gttaaggaac tcggcaaaat
     3601 gaccccgtaa cttcgggaga aggggtgctg actttaagtc agccgcagtg aataggccca
     3661 agcaactgtt tatcaaaaac acagctctct gctaaatcgt aagatgatgt atagggggtg
     3721 acgcctgccc ggtgctggaa ggttaagagg agtgcttagc gtaagcgaag gtatgaattg
     3781 aagccccagt aaacggcggc cgtaactata acggtcctaa ggtagcgaaa ttccttgtcg
     3841 ggtaagttcc gacccgcacg aaaggcgtaa tgatttgggc actgtctcaa cgagagactc
     3901 ggtgaaattt tagtacctgt gaagatgcag gttacccgcg acaggacgga aagaccccat
     3961 ggagctttac tgcagtttga tattgagtgt ctgtaccaca tgtacaggat aggtaggagt
     4021 ctaagagatc gggacgccag tttcgaagga gacgctgttg ggatactacc cttgtgttat
     4081 ggccactcta acccagatag gtgatcccta tcggagacag tgtctgacgg gcagtttgac
     4141 tggggcggtc gcctcctaaa aggtaacgga ggcgcccaaa ggttccctca gaatggttgg
     4201 aaatcattcg cagagtgtaa aggtataagg gagcttgact gcgagagcta caactcgagc
     4261 agggacgaaa gtcgggctta gtgatccggt ggttccgtat ggaagggcca tcgctcaacg
     4321 gataaaagct accctgggga taacaggctt atctccccca agagttcaca tcgacgggga
     4381 ggtttggcac ctcgatgtcg gctcgtcgca tcctggggct gtagtcggtc ccaagggttg
     4441 ggctgttcgc ccattaaagc ggcacgcgag ctgggttcag aacgtcgtga gacagttcgg
     4501 tccctatccg tcgcgggcgt aggaaatttg agaggatctg ctcctagtac gagaggacca
     4561 gagtggactt accgctggtg taccagttgt cttgccaaag gcatcgctgg gtagctatgt
     4621 agggaaggga taaacgctga aagcatctaa gtgtgaaacc cacctcaaga tgagatttcc
     4681 catgattata tatcagtaag agccctgaga gatgatcagg tagataggtt agaagtggaa
     4741 gtgtggcgac acatgtagcg gactaatact aatagctcga ggacttatcc aa
//
LOCUS       DAYYYC010000083         4664 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.083, whole genome shotgun sequence.
ACCESSION   DAYYYC010000083 DAYYYC010000000
VERSION     DAYYYC010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4664
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.083"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            102..467
                     /locus_tag="ACHBV5_002024"
     CDS             102..467
                     /locus_tag="ACHBV5_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFM9967755.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSRLISQEQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSH"
     gene            454..2304
                     /locus_tag="ACHBV5_002025"
     CDS             454..2304
                     /locus_tag="ACHBV5_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
                     /protein_id="HFM9967756.1"
                     /translation="MVVTKHFATHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSYEEMVEMYNVNFTNNDKLYEYRNDRQEKHQQNIHAHHLIQSFSPEDNLTPEEINR
                     IGYETIMELTGGRFRFIVATHTDKDHIHNHILINAIDCNSDKKLIWNYALERNLRMIS
                     DRISKMAGAKIIEKRFSYRDYQKYRATSHKFELKQRLYFLMQQSKSFDDFLEKAEQLH
                     VHIDFSQKHSRFMMTDRAMTKPIRGRQLSKRDLYDEDFFRMHFTKQEIASRLEFLLNC
                     VNSLEGLLTKSKELNLTIDLKQKNVIFILEENGKQFSLSHKKISDEKLYDVNFFQDYF
                     KNKEVGVSEGIENLQAQYRAFQEERDKEKVSTEEIEEAFETFKEKRDAVHEFEVKLTE
                     HQIEKLVDEGIYIKVSFGINQSGLIFIPNYQLDIMEEENQKKYKVYIRETTSYFVYNK
                     EHSDKNQYIKGRTLIRQLTNDSRVIPYRRPTVERLQEKISEISLLIELTETDKKYQDI
                     KDNLVSEIAELDIKLTQTNEKIATLNKMAEVLINSKSEGSGSQKLARHEFSKLNMTES
                     TTLEQVNEELLKLQQEFGNVLDEYEKTIRKLGQLFKVFDECINKEIMNEI"
     gene            2560..3992
                     /locus_tag="ACHBV5_002026"
                     /pseudo
     CDS             2560..3992
                     /locus_tag="ACHBV5_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886556.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(4474..>4664)
                     /locus_tag="ACHBV5_002027"
     CDS             complement(4474..>4664)
                     /locus_tag="ACHBV5_002027"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFM9967757.1"
                     /translation="CLYAKGIRYKYKYYSRRHSSLTRPNLINQCFQTKGKNEIWLGDL
                     TYIPTKAGTLYLSLYICL"
BASE COUNT         1613 a          766 c          896 g         1389 t
ORIGIN      
        1 caatcttatt gacctgcgtt caagaattga ttgcggaagt caatcaagta cagtcactca
       61 gtcgtgggtt tcgtgaaaaa tacatgagat aggaggctac tatggtttat cgttatcgta
      121 ccaatctcaa aaaagtattt ctaacagatt cagaattaca ccaattgaat gaacggattg
      181 ctaagagcaa ttgtcaaaat ttttcagtct atgccagaaa agttttgctt aatcccaata
      241 tgtcatttgt cacgattaac acggatactt atgaccagtt agtttttgaa ttgagacgga
      301 tcggaaataa cattaatcaa attgcgcgtg ctatcaatca aagccgtctg atttctcagg
      361 aacagttaca agaattgagt aaaggagtcg gagagttgat caaggaagtg gacaaagaat
      421 ttcaagtgga agtgaaaaga ttgaaggagt ttcatggtag tcactaagca ttttgcgaca
      481 cacggaaaaa aatatcgtag gcgtttaatt aagtatatcc tcaatcctga taaaacggac
      541 aatttgaaat tagtatctga ttttggtatg agcaattact tagactttcc tagctatgaa
      601 gaaatggtag aaatgtacaa tgtcaacttt accaataatg acaagttgta cgaatacaga
      661 aatgaccgac aagaaaaaca ccaacaaaat attcatgccc atcacctcat tcaatcattt
      721 tctcctgaag ataatctgac acctgaagaa attaaccgca ttggttatga gaccattatg
      781 gaattaacag gaggccgttt tcgtttcatc gtagcgactc atacagacaa agatcatatt
      841 cataatcaca tcttaatcaa cgccattgac tgtaattcag ataaaaagtt gatatggaat
      901 tatgccttgg aacgaaacct tcgtatgatt tcagaccgca tttctaaaat ggctggggcg
      961 aaaattattg aaaagcgttt ctcttaccgt gactatcaaa aatatagagc gactagccat
     1021 aagtttgaac taaagcaacg tctttatttt ttgatgcagc agtcaaaatc ctttgatgat
     1081 tttttagaaa aagcagagca attacatgtt catattgatt ttagtcagaa gcatagtcga
     1141 ttcatgatga cggatcgggc aatgacaaaa ccaattcgag gacgtcaact cagtaaacga
     1201 gatttatatg atgaagattt ttttagaatg cattttacca agcaagagat tgcaagtcgt
     1261 ttagaatttt tgttgaactg tgtcaattct ttagaagggt tactaacaaa atcaaaagaa
     1321 ttgaatctaa ccattgactt aaaacaaaaa aatgtaatct ttatacttga agaaaatgga
     1381 aagcaattca gtctgagtca taaaaaaata agtgatgaga aattatatga tgtcaatttt
     1441 tttcaagatt attttaaaaa taaggaagta ggtgtttcag aaggaataga aaatctacag
     1501 gcacagtacc gtgcttttca agaagaacga gataaggaga aggtatctac tgaagaaatt
     1561 gaggaagcct ttgagacatt taaggaaaaa cgagatgccg ttcatgaatt tgaagtaaaa
     1621 cttacagaac accaaattga gaagttagtt gatgagggga tttatatcaa agtgtccttt
     1681 ggtataaatc agagtggtct tattttcatt cctaactatc aactggatat tatggaagaa
     1741 gaaaatcaga aaaaatataa agtctacatt cgtgagacaa cctcatattt tgtctataac
     1801 aaagaacatt cggataagaa tcagtatatc aaagggagaa ccttgattag gcagctaacc
     1861 aacgatagtc gagtaatacc atacagaaga ccgactgttg aaagacttca agaaaagatt
     1921 tctgagatta gcctcttgat tgagttaact gagacagata agaaatacca agacattaaa
     1981 gacaacttgg tttccgaaat agcagagcta gatataaaac tgactcaaac aaatgaaaaa
     2041 attgccacct taaataagat ggcggaagta cttatcaatt ctaagagtga aggttcgggt
     2101 agccaaaaac tagctaggca tgaattttct aaattgaaca tgacagaatc aacaacttta
     2161 gaacaagtca atgaagaact tttgaagtta caacaggaat ttggtaatgt tcttgatgag
     2221 tatgagaaaa caataagaaa gcttggacaa ttatttaagg tttttgatga gtgtatcaat
     2281 aaagaaatta tgaatgaaat ataaatcaga ctgaagacaa actcaaattt ttttggatat
     2341 cttttctgtt tatggttgcc aatatcggtt taacttctaa aacaaacatt aataaaaatg
     2401 cattcaaaga cgattttacc tattttacga ttacgcttcg accccaaatc attaaagttg
     2461 tctatgctct atcattgcat cactggactt gtcaagagtt aagataattc ggagtccact
     2521 gaaaaagtca tcgtatgatg gtatactaaa gatgaggtga tggtatgctt gataatcgat
     2581 gttagtccct attctactct gtgtgatatt gttgttccca aaactcattt tttacgacag
     2641 ctaatggaac tctgtgattt tagttttatt tatgacgagc tggaaaagaa ttatcaacct
     2701 gacttcggat gtcgttccta ctctctcctt atcatgatgt tcaagtatct cttattaaaa
     2761 gacatctata agttgtccga tgtggatgtg gtggagcgct ccttttctgg tatgaccttc
     2821 aaatacttcc ttggtctagc tcctgttatt gaaccgtcct cattgactaa attccgaaaa
     2881 cttcggaaca aagatgaacg attacttgat ttgctcatcg ctaaatctgt tcagattgcg
     2941 atagagctcg gtctgattaa aagtaacatt ctcattgtgg atgcgactca taccaaagtt
     3001 cattacaatc acaagaaacc tcaagaagtc ctccgagaac gctcaaaagc cttgcgtaaa
     3061 acgatttatc agtattcgga atatatcaag gcagaatttc ctagtaagcc tcaggaagat
     3121 actctagtag ctgaattaag atatacacaa gaagtaatat cagtccttga gaagcatgac
     3181 gaattgactg gaataccagc tatctcacaa aattcaatta ccttaaagaa gctgtagagg
     3241 atgacttaga gcacttggaa tcctctgtca aagaagaagc aagaattgga cataagtcag
     3301 ccgatagttc cttttacggg tacaaagagc attttgccat gaccgatgaa cggattatta
     3361 ctgcctgtgt ggtgacatcg ggtgaaaaaa gtgatggtcc tgttttagaa gaactctatc
     3421 acaaatctaa ggataatggc gtgacgattg aagctattgt tggagatagg gcctactctg
     3481 ggaaggataa tatgcaattt accaagaaag aacgtgtgca ttgagtcgct aggccatatc
     3541 caactatttc aaaaggcttt cgtaggaagg aagatgagtt tttctataac aaggacgcag
     3601 gtctctttgt ttgtccagaa gggcatatgg cactaaagaa ggaaaagaca ggaagaagga
     3661 cggctcagga aacccactat tttgacatca agcactgtca aatatgccct tcaaaagtgg
     3721 gctgttataa agaaggggct aagtctaaga cttatttgat accccttaag agcgatgaac
     3781 atattttcca gaagaggttt caggaagcgc cctattttaa agaaaaggcc aaacatcgct
     3841 acaagataga agccaaaaat gcggaacttg aaaacagaca tggtcttaat gtagctagag
     3901 caccaggtct tttaaacatg gagttacaag ccgccacaac catatttgtg gttaatatga
     3961 agaggattat aactctaata aaccaaaaat aaggaaaagc aaagaggaat ctatccaagc
     4021 aggagataga tccctctttt ttcattttag ttgaactgta gagcttactt tttcagtgga
     4081 ctcgatgatt agtgactatt tttttcaaac tctattagtt attggtaccc taatgccgaa
     4141 tggagatatt taggattgta atagatttca atatatttaa agatttcgtt caatagttgc
     4201 gaaattggca tcattgacaa gttctctttt tatgttttgt aaaaggattc catgggtgca
     4261 ttatcatatg gattgccttt tcgactcagg ctagacttgc atcttttctg tttaaggagt
     4321 tcttgaaatc tagctccagt atattgagat ccttgatcgg tatggccgac tagttcttat
     4381 ttgagatttt ctctatgata agcttgattg aaaacattcg ttaccaactt atcttgcatt
     4441 cgatttccca ttgcctaacc aacaattttt ctgctataaa catatatata atgataaata
     4501 aagagtacct gcttttgtcg gaatataagt taaatccccc agccagattt catttttacc
     4561 ttttgtttga aaacactgat taatcaaatt gggtcgtgtt aatgaggaat gccgacggct
     4621 atagtacttg tatttatagc ggattccttt agcatagaga caaa
//
LOCUS       DAYYYC010000084         4527 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.084, whole genome shotgun sequence.
ACCESSION   DAYYYC010000084 DAYYYC010000000
VERSION     DAYYYC010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4527
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.084"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..1119
                     /gene="cpoA"
                     /locus_tag="ACHBV5_002028"
     CDS             <1..1119
                     /gene="cpoA"
                     /locus_tag="ACHBV5_002028"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HFM9967758.1"
                     /translation="KFPLFSSSLSFLLLILFKENDIIVVMEKKKLRINMLSSSEKVAG
                     QGVSGAYRELVRLLHRAAKDQLIVTENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKI
                     GYVHFLPATLEGSLKIPFFLKGIVKRYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREK
                     VTYIPNFVNKEKWHPLPQEEVVRLRTDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEE
                     LPQITFIWAGGFSFGGMTDGYEHYKKIMENPPKNLIFPGIVSPERMRELYALADLFLL
                     PSYNELFPMTILEAASCEAPIMLRDLDLYKVILEGNYRATAGREEMKEAILEYQANPA
                     ALKDLKEKAKNISREYSEEHLLQIWLDFYEKQAALGRK"
     gene            1135..2460
                     /locus_tag="ACHBV5_002029"
     CDS             1135..2460
                     /locus_tag="ACHBV5_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFM9967759.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            2491..2667
                     /locus_tag="ACHBV5_002030"
     CDS             2491..2667
                     /locus_tag="ACHBV5_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFM9967760.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIVPVATDY"
     gene            2726..2860
                     /locus_tag="ACHBV5_002031"
     CDS             2726..2860
                     /locus_tag="ACHBV5_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFM9967761.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            2924..4234
                     /gene="obgE"
                     /locus_tag="ACHBV5_002032"
     CDS             2924..4234
                     /gene="obgE"
                     /locus_tag="ACHBV5_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFM9967762.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            4244..4402
                     /locus_tag="ACHBV5_002033"
     CDS             4244..4402
                     /locus_tag="ACHBV5_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967763.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT         1334 a          774 c         1073 g         1346 t
ORIGIN      
        1 aaatttcccc tcttttcctc tagtctctcc tttcttttgc tgattttatt caaagaaaat
       61 gatataatag tagttatgga gaaaaagaaa ttacgcatca atatgttgag ttcaagtgag
      121 aaagtagcag gacagggagt ttcaggtgct taccgtgaat tagttcgtct tcttcaccgt
      181 gctgccaagg accaattgat tgttacagaa aatcttccga tcgaggcaga tgtgactcac
      241 tttcatacga ttgattttcc ctattattta tcaaccttcc aaaagaaacg ctcagggaga
      301 aagattggct atgtgcattt cttgccagct acacttgagg gaagtttgaa aattccattt
      361 ttcttaaagg gaattgtgaa acgctatgta ttttcttttt acaaccggat ggagcacttg
      421 gttgtggtca atcctatgtt tattgaggat ttggtagcag ctggtattcc acgtgaaaaa
      481 gtgacctata ttcctaactt tgtcaacaag gaaaaatggc atcctctacc acaagaagag
      541 gtagtcagac tgcgcacaga tcttggtctt agtgacaatc agtttatcgt agtaggtgct
      601 gggcaagttc agaaacgtaa agggattgat gactttatcc gtctggctga ggaattgcct
      661 cagattacct ttatctgggc tggtggcttc tcttttggtg gtatgacaga tggttatgaa
      721 cactataaga aaattatgga aaatccccct aaaaatttga tttttccagg cattgtatcg
      781 ccagagcgga tgcgcgaatt gtatgctcta gcggatcttt tcttgttgcc tagttacaat
      841 gagctctttc ctatgactat tttagaagct gcgagttgtg aggctcctat tatgttgcgt
      901 gatttagatc tctataaggt gattttggag ggaaattatc gggcgacagc gggtagagaa
      961 gagatgaaag aggctatttt ggaatatcaa gcaaatcctg ctgccttaaa agatctcaaa
     1021 gaaaaggcta agaatatttc cagagagtat tctgaagagc atctgttaca aatctggttg
     1081 gacttttatg agaaacaagc cgctttaggg agaaagtaaa aagtgaggta atctatgcga
     1141 attggtttat ttacagatac ctattttcct caggtttctg gtgttgcgac cagtattcga
     1201 accttgaaaa cagaacttga aaagcaggga catgctgttt ttatctttac gacgacagat
     1261 aaggatgtca atcgctacga agattggcaa attatccgca ttccaagtgt tcctttcttt
     1321 gcttttaagg atcgtcgctt tgcctaccga ggttttagca aggcacttga aattgctaaa
     1381 cagtatcagc tagatattat ccatactcag acagaatttt ctcttggcct gttggggatt
     1441 tggattgcgc gtgaattgaa aattccagtc atccatacct atcacaccca gtatgaagac
     1501 tatgtccatt atattgctaa ggggatgttg atccgaccga gtatggtcaa gtatctggtt
     1561 agaggtttcc tgcatgatgt ggatggggtt atttgcccta gtgagattgt ccgtgacttg
     1621 ctatctgatt ataaggtcaa ggttgaaaaa cgggtcattc ctactgggat tgaattagcc
     1681 aagtttgagc gtccggaaat caagcaggaa aatttgaaag aactgcgtag taaactaggg
     1741 attcaagatg gtgaaaagac gttgcttagt ctttcgagaa tctcctatga aaaaaatatt
     1801 caagcagttt tagtagcctt tgctgatgtt ctgaaagagg aagacaaggt taaactggta
     1861 gtagctgggg atggccctta tctgaatgac ctcaaagagc aagcccagaa cctagagatt
     1921 caagactcag tcatctttac agggatgatt gctcctagtg agacggctct ttactataaa
     1981 gcggcggatt ttttcatttc ggcatcgaca agcgaaacgc aaggtttgac ctacttggaa
     2041 agcttagcca gtggaacacc tgtcattgct cacggaaatc cttatttgaa caacctcatc
     2101 agtgataaaa tgtttggaac cttgtactat ggagaacatg atttggctgg tgctattttg
     2161 gaagccctga ttgcaacacc agacatgaac gagcatacct tatcagagaa attgtatgag
     2221 atttcagctg agaactttgg gaaacgagtg catgagtttt atctggatgc cattatttca
     2281 aataacttcc agaaagattt ggctaaagat gatacggtca gtcagcgtat ctttaagaca
     2341 gttttgtatc ttcagcaaca ggtggttgct gtacctgtaa aaggatctag acgcatgttg
     2401 aaggcttcaa aaacacagtt gatcagtatg agagactatt ggaaagacca tgaagaatag
     2461 aaagaggaac agctatgaaa aaaacaatta atgagaagcg gtcgtgataa aaagattgcg
     2521 ggtgtttgtg ctggggtggc ccattatctg gatatggatc cgactatcgt tcaagtcatt
     2581 tggggtgttc ttacttgctg ttacggagct ggaattgtag cttacattat tttatggatt
     2641 atcgtaccag tagcaactga ctattgaaaa ctagctcaat tcatgctaag ataatagaaa
     2701 atagaatgta acgaaggaga gaaaaatggc atttggagat aatggaaatc gtaaaaaaac
     2761 tatgtttgag aaaataacct tgtttatcgt gattatcatg ctagtagcaa gtttattggg
     2821 aatttttgca actgcaattg gtgccctcag taatctataa aatagattca agaaaattta
     2881 gtgactggga tttcccagcc cttttttaaa gtgagaagaa ataatgagta tgtttttaga
     2941 tacagctaag attaaggtca aggctggtaa tggtggcgat ggtatggttg cctttcgtcg
     3001 tgaaaaatat gtccctaatg gaggcccttg gggtggtgat ggtggtcgtg gaggcaatgt
     3061 ggtcttcgtt gtagacgaag gattacgtac cttgatggat ttccgctaca atcgtcattt
     3121 caaggctgat tctggtgaaa aagggatgac caaagggatg catggtcgtg gtgctgagga
     3181 ccttagagtt cgagtaccac aaggtacgac tgttcgtgat gcggagactg gcaaggtttt
     3241 aacagatttg attgaacatg ggcaagaatt tatcgttgcc cacggtggtc gtggtggacg
     3301 tggaaatatt cgtttcgcga caccaaaaaa tcctgcaccg gaaatctctg aaaatggaga
     3361 accaggtcag gaacgtgagt tacaattgga actaaaaatc ttggcagatg tcggtttagt
     3421 aggattccca tctgtaggga agtcaacact tttaagtgtt attacctcag ctaagcctaa
     3481 aattggtgcc taccacttta ccactattgt accaaattta ggtatggttc gcacccaatc
     3541 aggtgaatcc tttgcagtag ccgacttgcc aggtttgatt gaaggggcta gtcaaggtgt
     3601 tggtttggga actcagtttc tccgtcacat cgagcgtaca cgtgttatcc ttcacatcat
     3661 tgatatgtca gctagcgaag gccgtgatcc atatgaggat tacctagcta tcaataaaga
     3721 gctggagtct tacaatcttc gcctcatgga gcgtccacag attattgtag ctaataagat
     3781 ggatatgcct gagagtcagg aaaatcttga agaatttaag aaaaaattgt ctgaaaatta
     3841 tgatgaattt gaagagttac cagctatctt cccaatttct ggattgacca agcaaggtct
     3901 ggcaacactt ttagatgcta cagctgaatt gttagacaag acaccagaat ttttgctcta
     3961 cgacgagtcc gatatggaag aagaagctta ctatggattt gacgaagaag aaaaagcctt
     4021 tgaaattagt cgtgatgacg atgcgacatg ggtactttct ggtgaaaaac tcatgaaact
     4081 ctttaatatg accaactttg atcgtgatga atctgtcatg aaatttgccc gtcagcttcg
     4141 tggtatgggg gttgatgaag cccttcgtgc gcgtggagct aaagatgggg atttggtccg
     4201 cattggtaaa tttgagtttg aatttgtaga ctaggagact ggtatgggag ataaaccgat
     4261 atctttccga gatgcggatg gtaattttgt ttccgccgca gacgtttgga atgaaaagaa
     4321 attggaagaa ctatttaatc gtctcaatcc aaatcgtgcc ttgagattgg cacgaactaa
     4381 aaaggaaaat ccatctcagt aaagaagcta aaaaatcccg gctctttgtc aactgtagtg
     4441 ggttgaagaa aagctaagct cgagaaagga caaattttgt cctttctttt ttgatattca
     4501 gagcgatgaa aatccgtttt ttgaagt
//
LOCUS       DAYYYC010000085         4258 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.085, whole genome shotgun sequence.
ACCESSION   DAYYYC010000085 DAYYYC010000000
VERSION     DAYYYC010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.085"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            148..1023
                     /gene="pdxS"
                     /locus_tag="ACHBV5_002034"
     CDS             148..1023
                     /gene="pdxS"
                     /locus_tag="ACHBV5_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HFM9967764.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            1024..1608
                     /gene="pdxT"
                     /locus_tag="ACHBV5_002035"
     CDS             1024..1608
                     /gene="pdxT"
                     /locus_tag="ACHBV5_002035"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HFM9967765.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEDVEILATVDNQIVA
                     AQEKNMLVTSFHPELTDDAHLHQYFIEMCKEKRQ"
     gene            2165..2896
                     /locus_tag="ACHBV5_002036"
     CDS             2165..2896
                     /locus_tag="ACHBV5_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9967766.1"
                     /translation="MVNNVAVKVSNLSKEFLLGQDKTVSILKDISLSVNYGEFVSILG
                     VSGSGKSTLLSCLSSLSEPTSGEVVINGVNPYTLKEGKLAKFRRQDIAIIFQNYNLVP
                     ALPVLENVTLPLRLSGKSVDSNKVKKMLDSLNFKAELSSLVATLSGGEQQKVAITRAI
                     IADSKIIFADEPTGALDSVSRKLIFETLRNLASQGKCVLMVTHDIELASKTDRALILK
                     DGKISRQIIKPSADELYQALESSKD"
     gene            2914..4230
                     /locus_tag="ACHBV5_002037"
     CDS             2914..4230
                     /locus_tag="ACHBV5_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFM9967767.1"
                     /translation="MLKLIIYQFQYSKRQWLGTIPLLFVSSLIVGTSLFGIASSIKTA
                     NINASQLFQMLIIFGGTTLFFLISNNIRLLIDIFKKDYQLWTILGASRTQLSLLVSGQ
                     FYLMAVIVSSIGTILSFIMADSYYKFLQNLLGRDELPDLVITANIQSILLSIFIVPTI
                     VGIGAYFYSSRILKISSILKPKKKKRKVTVTGFVNISVRLFLWLLCIGSIVSAGFIRN
                     KEIIEKQSSIILFLLIIHILIIQSLSPSIQMFLIKFLMRIFPTENYVINTGFWNLLSN
                     PSYLKSIQTSMSMGVTLISGFILYTQNMYSFMNTANGVNEARASFIAYMSAPIILIIT
                     SSISLTILSSNKDIEDIKQLKTLGVSRLQLFKIRIGEAIIHSVLILLVSVIFNLIILI
                     LVSIIGQFLGRSLVDISGFWQPSLIVISLLVIFYSITKGFYLFQDR"
BASE COUNT         1365 a          674 c          821 g         1398 t
ORIGIN      
        1 gaatgagcta tctggcctta agttaaggtc agatagtttt tagctaatct gtccccatac
       61 aattatagtt tttttatctt gtgcttcatt ctgttctgac ttaaaatgaa aaggtagcta
      121 ccaatacaaa tgatgaggat aaaacaaatg actgaaaatc gttatgaact aaataaaaac
      181 ttggcacaga tgctcaaggg tggtgttatt atggatgtgc agaatcctga acaggctcgt
      241 atcgcagaag ctgctggtgc ggcagctgtg atggccttgg aacgaattcc ggctgatatt
      301 cgtgcagctg gaggagtttc ccgcatgagc gacccaaaga tgattaagga aatccaagaa
      361 gcggttagta ttccagtaat ggctaaggtc agaatcgggc attttgttga agctcagatt
      421 ttagaggcta ttgaaattga ttatatcgac gagagtgaag ttctatctcc agctgatgac
      481 cgtttccatg tggacaagaa agaattccaa gttccttttg tctgtggtgc taaggatttg
      541 ggtgaagcct tgcgtcgtat cgctgaaggt gcttccatga ttcgtaccaa aggagaacca
      601 gggacagggg atatcgtcca agctgttcgt catatgcgta tgatgaatca ggaaattcgc
      661 cgcattcaaa acttacgtga ggacgagctt tatgttgctg ccaaggattt gcaagtccct
      721 gtagaattgg tccaatatgt tcatgaacat ggaaaattgc cagttgtaaa tttcgctgct
      781 ggaggtgttg caacgccagc agatgctgcg ttaatgatgc aactaggggc agagggggtc
      841 tttgtcggtt caggtatttt caagtcagga gatcctgtta aacgagcgag tgccattgtt
      901 aaggctgtga ctaacttccg taatcctcaa atcctagctc aaatctctga agatttagga
      961 gaagccatgg ttggtattaa tgaaaatgaa atccaaattc tcatggctga acgaggaaaa
     1021 tagatgaaaa tcggaatatt ggccttgcaa ggggcctttg cagaacatgc aaaagtgcta
     1081 gatcaattag gtgtcgagag tgtagaactc agaaatctag atgattttca gcaagatcag
     1141 agtgacttgt cgggtttgat tttgcctggt ggtgagtcta caaccatggg caagctctta
     1201 cgtgaccaga acatgctact tcccatccga gaagccattc tatctggctt accagtgttt
     1261 gggacctgtg cgggcttaat tttgctggct aaggaaatca cttctcagaa agagagtcat
     1321 ctaggaacta tggatatggt ggtcgagcgt aatgcttatg ggcgccaatt aggaagtttc
     1381 tacacggaag cagaatgtaa gggagttggc aagattccaa tgacctttat ccgtggtcca
     1441 attatcagca gtgttggaga agatgtagaa attctagcaa cagttgataa tcaaatcgtt
     1501 gcagcccaag aaaaaaatat gttggtaact tcttttcatc cagaattgac agatgatgct
     1561 cacttacacc agtactttat cgaaatgtgt aaagaaaaaa gacagtaaaa aagctcaaaa
     1621 aatcacttcc tgtgctatac tgtaattgaa atttttttag tttttgcgtt agaactgttt
     1681 cctcagtcct agcgcctttt ctttttgata agtctgcttg gtggagagta gtttgtaaac
     1741 gattctgaga atcttatgag cacaagcaat gacggctttc atcttgcttc ctctttggga
     1801 aattcgattg taaaactcta agcaggcaga gcctgcttag agttttacat atgctactat
     1861 ctttgttata gctaacttaa attctcattt attaagtata cctaagtttt atgtttaaat
     1921 tttgtataga atagttgtat cacttaacaa agctatgttt acgctttcaa tcaagtctca
     1981 tttatgatac tattatggta atagaaaaaa ttcttagttc gctaaagacc tttattcgag
     2041 atccagagga aatagaaatt ttatccatta aaaatacgtt tcataagtta cttacttgat
     2101 attaatagaa ttccaatatt gtataattaa atcaaagatg acactggaat caggaggatt
     2161 tattatggtt aataatgtag ctgttaaagt ctcaaacctt tcaaaagaat ttttgttagg
     2221 gcaagacaaa actgtctcta ttttgaaaga tatttcctta tctgtcaatt atggggaatt
     2281 tgtatcaata cttggtgtca gtggttctgg aaagtctact ttgctaagtt gcttatcaag
     2341 tttatctgaa ccaacaagtg gcgaagttgt tatcaatggt gtaaatccat ataccttaaa
     2401 agaagggaag cttgctaaat ttagaagaca agatattgca ataatttttc aaaactataa
     2461 tctggtacct gctctacctg tactagaaaa tgttacactt cctctgagac tatcaggaaa
     2521 gagtgttgat agcaataaag taaaaaaaat gttggatagt ttgaatttta aagcagaact
     2581 atcatcatta gttgctacct tatcaggtgg agaacagcaa aaagtggcta ttactcgtgc
     2641 aataatagct gatagtaaaa ttatttttgc tgatgagcca acaggagctc tggacagcgt
     2701 ctcaagaaaa cttatatttg aaacacttcg taatttagcg agtcaaggaa aatgtgttct
     2761 tatggtcact catgatattg agttggcttc aaaaactgac agagcactca ttttaaaaga
     2821 cggaaaaata tctcgacaaa ttattaaacc ttcagctgat gagctctacc aagcacttga
     2881 aagtagtaaa gattaatttg aggaggattt attatgctaa aattaatcat ttaccaattt
     2941 cagtactcaa aaagacaatg gttaggaaca ataccattac tatttgtatc tagcctgatt
     3001 gttggaacat ctttatttgg tattgctagt tcaatcaaga ctgctaatat taacgcttca
     3061 caactttttc aaatgctaat aatttttggc gggactactc tatttttcct tatttcaaat
     3121 aatataagac tgctaataga tatctttaaa aaggattacc aattatggac tatcttaggc
     3181 gcaagcagaa ctcagctatc tttattagta tctggacagt tttatttaat ggcagtgatt
     3241 gttagtagta ttggtacaat actttcattt atcatggcag atagttatta caaattttta
     3301 caaaatttat taggaagaga tgagttacct gatttagtta ttacagccaa cattcaatca
     3361 attttattga gtatttttat agtcccaaca attgtcggga taggggctta cttttattca
     3421 agtcgaatac ttaaaatatc atcaatatta aaaccaaaaa agaaaaaaag aaaagttaca
     3481 gtaactggat ttgttaacat ctctgttcgt ttattcctat ggctactatg tataggttct
     3541 attgtttcag caggttttat cagaaacaaa gaaataattg aaaaacagtc aagcataata
     3601 ttatttttat taattattca catccttatt attcaatcac tatctccatc aattcaaatg
     3661 tttctaataa aatttttaat gaggatattt ccaactgaaa attatgtaat taatacaggc
     3721 ttttggaatc tactatccaa tcctagctat ttgaaaagta tacaaacttc aatgagcatg
     3781 ggagtaactc tcatttctgg gtttattctt tacacccaaa atatgtattc attcatgaat
     3841 acagcaaacg gagtaaacga agcaagagct tcctttattg cttatatgtc tgcaccaatt
     3901 attctgatta ttactagttc tatttctctt acaattttat cttctaataa agatattgag
     3961 gacattaaac agttaaagac actgggagtg tcaagattac aactttttaa aatacgtata
     4021 ggcgaggcaa taatacattc ggtgttaatt ttattagtgt cagtaatttt caatttaatt
     4081 attttaattt tagttagcat tattggccaa tttttaggtc gtagtttagt agatatatca
     4141 ggtttctggc aaccgagtct tatagttatt tctttgttag ttatttttta tagtattaca
     4201 aagggatttt atttatttca agatagataa attggaatag ttactgaacc aaaaagaa
//
LOCUS       DAYYYC010000086         4158 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.086, whole genome shotgun sequence.
ACCESSION   DAYYYC010000086 DAYYYC010000000
VERSION     DAYYYC010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.086"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(174..839)
                     /locus_tag="ACHBV5_002038"
     CDS             complement(174..839)
                     /locus_tag="ACHBV5_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFM9967768.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(853..2232)
                     /locus_tag="ACHBV5_002039"
     CDS             complement(853..2232)
                     /locus_tag="ACHBV5_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFM9967769.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            complement(2797..3561)
                     /locus_tag="ACHBV5_002040"
     CDS             complement(2797..3561)
                     /locus_tag="ACHBV5_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HFM9967770.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            3638..3793
                     /locus_tag="ACHBV5_002041"
                     /pseudo
     CDS             3638..3793
                     /locus_tag="ACHBV5_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691454.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
     gene            3783..4066
                     /locus_tag="ACHBV5_002042"
                     /pseudo
     CDS             3783..4066
                     /locus_tag="ACHBV5_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
BASE COUNT         1341 a          973 c          792 g         1052 t
ORIGIN      
        1 gcccgtagct agtttcctag tttgatcttt gattttcatt gagtattact ctctcttgtc
       61 acttctttct attttaccat aaagtccagc ctttgaagaa cttttactag aagacaaggg
      121 gcttctgtct ctatttgcca tcttaggcat caaaaaagag gggtcatccc tctttacgaa
      181 ttcaatgcta ctagggtatc caaatactgg ttgttgatga ctgccaaaat ataggtatct
      241 gctttcaaga ggtcatctgg tccaaattca acatccaatg gggaattttc ctgctctcgg
      301 aaacccaaaa tattcagatt gtatttgcca cggaggtcta atttactcag actttgacct
      361 gcccaagact gaggaatttt catctccacg atagacacat ttttatccaa ctgaaagaca
      421 tcaacactat tatggaaaag aatggtctgt gctagagact gccccatttc atactctggc
      481 gagataaccg agtcagctcc aatcttttct agcactttct tagcggtctg acttttgacc
      541 ttagcaataa cagtcggtac ccccaaactc ttacagtgca taaccgcaag cacactcgac
      601 tccagatttt cacctgtcgc gactacaacg gtatcgcagg tatcaatccc tgctgatctc
      661 aataattctt catctgtgat gtcaccaatc actccacgcg ccaaaactgg ctcaaactga
      721 ttgatgcgct ctgcgtggtc atcaatagcg ataatattca tatcctgctt ggctagggca
      781 gctaggacac tgctcccaaa aattcccaag cccaaaattc caatcgtacg atctgacatg
      841 ctctttcctt tcttaaccaa tactaatatc tgctttcata tagtgaatca tatctttctt
      901 ttctggatgg taatctgcca agctaacaaa caaggtcaag ggaccaattc gtcccataaa
      961 cataagtggc atgataacac tgagagccaa tttcccaagg tcaggagtca gatttgccgt
     1021 tacaccaact gtactaagag ctgaaatggt ttcaaatacg aggtggataa agggaggatt
     1081 gcctttggct gttatcccta gcagaatcaa tcctatcaag aagctcatca aaaagataat
     1141 aaagacacta aaggattttt gaaccgttcg cggcgcgatc gttcgtctcg caacattggc
     1201 atgaggcaag cctagaagct cacttcgtgc aaagaccaag aggacaaaaa atgtcgtaat
     1261 cttgagtccc ccagctgttc ctccaggtgc cccacctaga aacatctgta agatataaat
     1321 caaaagagtc acaggatgag cctgagtata atctatcgta gaaaagccag ctgttcgcat
     1381 cgtcactgtt tgaaaaaagc taactaaaac cttatcggca acagggagat tgccaatcgt
     1441 tccagcattg ttccactcaa gaaagagagt agttgctgtt ccaaataaca acaaacctat
     1501 agtcaataat agtacaagct tcgtatgaaa gtgcagacgt ccttttttct ttcttcctac
     1561 atgaccagcc aaatcaaacc agaccataaa accaaggccg cctgtaataa tcaagcctgc
     1621 aatcaccaga ttgaccagta aatcggtctg aaaagcaaat aaactggtgc tccctaaatt
     1681 atcaaaaccg gcattacaga aggctgagat cgctagaaaa atggaactaa aaagaccacg
     1741 tccccagcca agttgaggaa taaggcgaaa actaagcaaa atagctccca agctctcaac
     1801 caaaaaggtc gtgagaaaaa tagaatagac aaactttctc aaagatcgag tttctccata
     1861 actaaaacta tcctgaatag ttgcacggct acgaagacta agcttttgct tgctctggat
     1921 atagaaaacc ccaataaagg tcatgagccc tagaccaccg atctgaatca agagcaaaca
     1981 gattatttgg ccccagatat tataggtgtg agctactgga agggttgaga gacctgtcac
     2041 acagactgca gagacagcag tgaaaagatg atcaaaataa gtcgctcgtg agctttcaac
     2101 ttggacaaag ggcaagctca aaagaagaga gcctagtaaa atgaccaagg caaaactcaa
     2161 aaaaatacga cgggctggcg ataaacgaga taagcctagc tctatttttt ccttagataa
     2221 tttgaataac atgtttccat tgtaccataa aaagttcgaa atgacttaga taggataagg
     2281 caaaatctac taacaccaag cctaaaaaat gccacctttt tattgatagc ttaggcaaga
     2341 acaatacttg atagatgtga ctataggtca aaaaagcaag acaggagctt ttaacgccag
     2401 ctactctata tgcttttcag gagaaaattt ctctttttga ttataggcaa tgagaaccaa
     2461 ggcatcgctt agaaagctag tcacaggttg ctcaaaacac tgttttgagg ttgtggatag
     2521 aactgacgaa gtcagtaaca tctatacggc aaggtgaagc tgacctggtt tgaagagatt
     2581 ttcgaagagt atcatttcat ctcactctaa atcttaccaa cataaaacgc atagtatcaa
     2641 aattttcatc acctgatatg atacgttttt ctgattttaa agatttttcc caacctcaac
     2701 atgcctagga caagaggaag gtgacctcgt ttaaacatat ttttgaaaag tatgagctag
     2761 acattttatg ataaaacaaa tcctttgcca gtacaactaa aggtggtgaa cacttgctaa
     2821 actcagttct agtgccttat taaaagcttc cgagccccag tcacgactgt cgtactggtc
     2881 caagtccgct agagaatctg ctgtgaacaa caattcaccc cagagaactc cacgcaattg
     2941 agctactgcc gcaagagcag aacactccat ctccacaaca gcacagcctt cttccttacg
     3001 ataagccacc ttttcagccg tttctcggta aaaaccatct gtggaccagg tcatgacttc
     3061 ttcataagga atccctctat catccaaaac tcgctcaatg gcagcaatag cctctggctg
     3121 catttccata taacgagaag gtgccacata gtggtaactg gctccttcat ctcgcagagc
     3181 gcgaacaggg actagaaagg cattttcctc tatatcagct aggacaccac aggtcccagt
     3241 agagataatc tgctccacac catagccaat caaccaatcc ataaactggg ctgctggagc
     3301 ggagccaaca ggagcctgag ccagacagac ctcctcaccc ttgtagttga tgacatagac
     3361 tggataggtc ttggtagcag aaacgaattc gccaacacag ttcgccccta cttccctcgc
     3421 atagcggtca atctcctcac ctaaaaaagc atagacacac ttctttggca actgcaaatc
     3481 caacccctcg tgattgggca tgataaccgc ctgaggatta tcatcaaact ctaaaatggg
     3541 aatcgcatgt ttctgaatca tagcccacct cctctaattt tgtactattg tatcaaaatc
     3601 tgaccgagtg tcaaggagga agctgatgaa ctgaggagaa aaacaagcct acatcgtcag
     3661 ttgccacagt agtttgcgca gctatatcgc agagcctatc ctcaagcaag caggatttac
     3721 cgtccaaaac cttgacggcg cttattcact atacaaaatg gttaacccag aaggagtaga
     3781 atatggaaac tagtatcagc atggctgact tttatagaaa atatcaaaat gaaaatctgg
     3841 aacttatcga tgtccgtgaa gcacatgaat tccaagcagg acccaaaaat cttccataaa
     3901 taccttagag caaggctaca aagaactcaa acctgaccat gaatactatg tcatttgtca
     3961 cggaggagtc cgctctgcat ctacctgcca atttctcagc tcccaaggcc tcaccgttac
     4021 caacgtagaa ggtggtatga atgcttggcc cggtcaagta gaataatcaa gaggagctgg
     4081 gcaaaaactc aatttcatga gaagatgaag taatactcaa tgaaaattaa agtgcaaact
     4141 aggaagttag ccgcaggc
//
LOCUS       DAYYYC010000087         3919 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.087, whole genome shotgun sequence.
ACCESSION   DAYYYC010000087 DAYYYC010000000
VERSION     DAYYYC010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3919
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.087"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(146..1207)
                     /gene="dinB"
                     /locus_tag="ACHBV5_002043"
     CDS             complement(146..1207)
                     /gene="dinB"
                     /locus_tag="ACHBV5_002043"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFM9967771.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            1556..3880
                     /gene="pflB"
                     /locus_tag="ACHBV5_002044"
     CDS             1556..3880
                     /gene="pflB"
                     /locus_tag="ACHBV5_002044"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFM9967772.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
BASE COUNT         1179 a          831 c          760 g         1149 t
ORIGIN      
        1 aaaaaccttg aaggggcaac tcttcaaggt tttatactct tagaaaatct cttcaaaccg
       61 cgtcagcttt atctgcaacc tcaaaacagt gttttgagca gcctgcggct agcttcctag
      121 tttgctcttt gattttcatt gagctttaaa atccagtcag ggtaatcccc aataggcgga
      181 cacctctttc tttctcgctt aattcttcat agagttgcag ggctatttgg cttatctgac
      241 tagcatcttg tgttttttga gcaagacttt ttcgtttggt aagagttgaa aagtcctcgt
      301 agcggatttt caaaatgaca atttttccag ctttttcttg ttgatgtaga ttgagagcga
      361 ctttttctga tagaagagtc agctcttttt tgatatcttc ctcagcaagg agaatcttcc
      421 cgtaggtttt ctccttgccg attgatttac ggatgcgatt ggatttgact ggagagttgt
      481 gaatgccacg agcctttcga tacagatcat agcctagtct accaaaacgg tctattaggg
      541 ttacctcagg aacttcaagt aaatcagcac cagtaaaaac gcccatttga tgaagacgtt
      601 ctactgtctt ttttcctact ccatgaaatt tggaaatatc catttgtttg agaaaatcct
      661 cagcctgttc aggtagaatc actgtcaaac catgtggttt ttgataatca ctcgccattt
      721 tagctaagaa tttgttgtaa gaaacgcctg cggaagcagt tagatggagt tcttgccaga
      781 tatctttttg aatgaggcga gcaattttga ccgctgactt gataccgagt ttattttctg
      841 tcacatccaa ataggcttcg tcaatgctca tgggttcaat caaatctgta tagcgcttaa
      901 aaatagctcg aatctggagt cccacagact tgtatttctc ataattccct gagataaaga
      961 cagcctgggg acaacgttca taagcttcct tggaactcat ggcagaatgg acaccaaaag
     1021 ctcttgcctc ataactacag gtagaaacga ctccccgtcc acctgtttgc cgagggtcgc
     1081 ttccaataat gacaggtttt cctctgagtt taggattatc cctgatttcc actgcagcaa
     1141 aaaaggcatc catgtcaata tggatgattt ttcttgacaa atcatttaac aaaggaaaaa
     1201 tcaacatgcc tagcaccttt ttatactctt cgaaaatctc ttcaaaccac gtcagctcta
     1261 tctgcaacct caaaacagtg ttttgagcaa tctgcggcta gcttcctagt ttgcttttcg
     1321 atttccattg agtgttactg cttattttct tttattatac ccttttttct gaaaaaaaga
     1381 aaaaaggact ttattttttc aaaaatataa tacagtttga aataaaatat agactgtttt
     1441 agaaaagaaa gtgtaaaaat agggaatttt cacttgttga aatcggttac tatatggtat
     1501 acttgtctta tgaatgtaac agatgactgt tactagaaaa aaagaggaca ttaatatggt
     1561 tgttaagaca gttgttgaag cacaagatat ttttgacaaa gcttgggaag gcttcaaagg
     1621 cgtagattgg aaagaaaaag caagtgtatc acgatttgta caagctaact acacacctta
     1681 tgatggagac gaaagcttcc ttgcaggacc aacagagcgt tcacttcaca tcaagaaaat
     1741 tgtagaagaa actaaagcac actacgaaga aactcgtttc ccaatggaca ctcgtccaac
     1801 atctatcgct gatatccctg ctggatttat cgacaaagaa aatgaagtta tctttggtat
     1861 ccaaaatgat gaactcttca aattgaactt catgccaaaa ggtggtatcc gtatggctga
     1921 aactacttta aaagaaaatg gatacgaacc agacccagct gttcacgaaa tcttcactaa
     1981 atatgtaaca acagttaacg acggtatttt ccgtgcctac acttcaaata ttcgtcgcgc
     2041 tcgtcatgca cacactgtaa ctggtcttcc agatgcatac tcacgcggac gtatcatcgg
     2101 tgtttacgca cgtcttgctc tttacggtgc agactacttg atgcaagaaa aagtaaacga
     2161 ctggaatgca atcaaagaaa tcgatgaaga aacaatccgt cttcgtgaag aagtaaacct
     2221 tcaataccaa gcattgcaac aagttgttcg cctgggtgac ctttacgggg ttgatgttcg
     2281 caaaccagcg atgaacgtga aagaagcaat ccaatgggtt aacattgctt tcatggctgt
     2341 ctgccgtgtg attaacggtg ctgctacatc tctaggtcgt gtaccaatcg tattggacat
     2401 ctttgcagaa cgtgaccttg ctcgtggtac atttactgaa tcagaaatcc aagaattcgt
     2461 tgatgatttc gttatgaaac ttcgtacagt taaatttgct cgtacaaaag cttatgacca
     2521 attgtactca ggtgacccaa cctttatcac aacttctatg gctggtatgg gtaacgacgg
     2581 tcgtcaccgt gttactaaga tggactaccg tttcttgaac acacttgaca acatcggtaa
     2641 ctcaccagaa ccaaacttga cagttctttg gactgacaaa ttgccataca acttccgtcg
     2701 ctactgtatg cacatgagcc acaaacactc ttctatccaa tacgaaggtg taacaacaat
     2761 ggctaaagac ggatatggtg aaatgagctg tatctcatgc tgtgtgtctc cacttgatcc
     2821 agaaaatgaa gaacaacgcc acaacatcca gtacttcggt gctcgtgtaa acgttcttaa
     2881 agcccttctt actggtttga atggtggtta cgacgatgtt cacaaagact acaaagtatt
     2941 tgatatcgaa ccaatccgtg acgaagttct tgaattcgaa tcagttaaag cgaactttga
     3001 aaaatctctt gactggttga ctgacactta cgtagatgcc ttgaacatca tccactacat
     3061 gactgataga tacaactacg aagctgttca aatggccttc ttgccaacta aacaacgtgc
     3121 caacatggga ttcggtatct gtggatttgc taacactgtt gatacattgt cagctatcaa
     3181 atacgctaca gttaaaccaa tccgtgacga agatggctac atctacgatt acgaaacaat
     3241 cggtgactac ccacgctggg gtgaagatga cccacgttca aacgaattgg cagaatggtt
     3301 gatcgaagct tacacaactc gtctacgtag ccacaaacta tacaaagacg cagaagctac
     3361 agtatcactt ttgacaatca catctaacgt tgcttactct aaacaaactg gtaactcacc
     3421 agttcacaaa ggtgtatacc tcaacgaaga tggttctgtg aacttgtcta aacttgaatt
     3481 cttctcacca ggtgctaacc catctaacaa agctaaaggt ggttggttgc aaaacttgaa
     3541 ctcactttct agccttgact ttagttatgc agctgacggt atctcattga ctacacaagt
     3601 atcacctcgc gctcttggta agactcgtga tgaacaagtt gataacttgg taacaatcct
     3661 tgatggttac ttcgaaaacg gtggacaaca cgttaacttg aacgttatgg acttgaacga
     3721 tgtttacgaa aaaatcatgt caggcgaaga cgttatcgta cgtatctctg gatactgtgt
     3781 aaacactaaa tacctcactc cagaacaaaa aactgaattg acacaacgtg tcttccacga
     3841 agttctttca atggatgacg ccttggatgc attgagctaa tcaagttcgg ctctttgtca
     3901 actgcagtgg gttgaagtc
//
LOCUS       DAYYYC010000088         3383 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.088, whole genome shotgun sequence.
ACCESSION   DAYYYC010000088 DAYYYC010000000
VERSION     DAYYYC010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3383
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.088"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(<1..215)
                     /locus_tag="ACHBV5_002045"
     CDS             complement(<1..215)
                     /locus_tag="ACHBV5_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CAT RNA binding domain-containing protein"
                     /protein_id="HFM9967773.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELV"
     gene            complement(515..3193)
                     /locus_tag="ACHBV5_002046"
     CDS             complement(515..3193)
                     /locus_tag="ACHBV5_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFM9967774.1"
                     /translation="MAVFVSLDGIVVEVLDVFSSFDGDSEFFLCKRLKDKSQFVMERS
                     RFEEMFQLQSSHLTTQEKLQLFTSVFAGRYDVYAKNFINEQGKIQYFPSYDYGWKQLP
                     PEKRSFQTLTNSVLKSHFRGETAIGIFPMHLDDSCHFLVLDFDEGDWKEAGLTIRRIA
                     RERQMEAHLEISRSGHGLHIWFFFEEAIPSREARLFGKKLIELAMQESMQLSFDSFDR
                     MFPNQDVLPKGGFGNLIALPFQGEAYHQGRTVFVDEQFQPYEDQWRYLQEIQRVSTAK
                     VALLIQEELGKQELDKGLKIVLSNMIQLEKSSVTPKTLFFLKNMASFSNPEFYLKQAM
                     RQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVVVEDRRKVQRSISVEFKGEL
                     TFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKTKTIILVHNKQLLDQWLDR
                     LNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKLVDVVMIQSLFKLENSQSL
                     LDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPERKNGHEPIVFQRIGEILH
                     TADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWIATDSARNQLILKDILAQV
                     AEGRNILVLVNRIQQIDVFEKLLKEKEVDDCYIISGKTKVRERTSLLETLEQLDKGFV
                     LLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIHRNYKDKSLVRIFDYVDIH
                     VPYLEKMFQKRQVAYRKMDYRAIEGEEKQFVYVDSRYEKVLIEDLAGERQECLLILPY
                     VHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKIKVSFTQSKIVTPILLVNK
                     TIVWYDAMPLLGKVDEMTILRLESASIVSELVAGLR"
BASE COUNT         1079 a          758 c          497 g         1049 t
ORIGIN      
        1 tacaccaact ccaaaggaac gttaataaac atctctgtaa aacgggtcat attatctcta
       61 tttttgagaa aaaaactttt ctcaatatca attggattta ctttatctcc aatttttctt
      121 ccaaaagcta ttccccttcc aaaaagaaga atatcgatat cttttttact ttgcgcaatt
      181 acggcattgt ggtttagtat tcgttttatg atcataaaat ttccctttta aaataaaagg
      241 aacctactta aaaacatcaa gaaacttctt ctgatgtgat taaataggtt cctgctcact
      301 tgtattagtg ataacatcct tttatttcaa tttttaatgg tgacatgaag cttaaataat
      361 taataactct gtaaccattt tcattttaag atatttcaat ctatttgtca agtacttgta
      421 gaaatttttt tattttgtgt gattcgaatg tgataatggc aacagtctca ctaaagaaat
      481 gaaaatcata catagaaatt tttaaaaatt ttctctatcg taaacctgcc actagttcag
      541 aaactatact agctgattcc aaacgtaata tggtcatctc atctaccttc cctaataatg
      601 gcattgcatc ataccaaaca atagtcttat tcaccaaaag aataggcgtt actatttttg
      661 attgagtaaa agacacttta attttctggc tcttcaactg gtctagccat gctttatttg
      721 caaccgtctc tggtatacat atctcaattt gactaatcct aaattctttt agaaaattca
      781 tcagttttgt ctggtgcaca taaggtaaaa taagcagaca ttcctgtctt tcccctgcta
      841 agtcctctat caacaccttc tcatatctac tatcaacata aacgaattgt ttctcctcac
      901 cctcaatggc acgataatcc atctttcgat aagctacttg tcgtttctga aacatctttt
      961 ctaaataagg aacatgaata tccacataat cgaaaatacg caccaaagac ttatccttgt
     1021 agtttctatg aatccgacct gcatactgaa ttaaattatt tttccaagaa aagggtgctg
     1081 ccaagataag cgtgtccaac tgaggtaagt caaaaccttc gccaatgtat tttccagtag
     1141 acaacaaaac aaacccttta tctaactgtt ctaacgtctc cagtaaactc gttctttctc
     1201 ggactttggt ttttccgcta ataatgtaac agtcatcaac ctctttctct ttcaataact
     1261 tttcaaagac atctatctgt tgaattcgat taactaaaac caagatattc cgtccttctg
     1321 ccacttgggc tagaatatcc ttgagaatca actgattcct cgctgagtct gtagcaatcc
     1381 aatcactgag ctgtataaaa ttacttgctt tggtcttttc aatctccaaa tgaccaaaag
     1441 aagtgaatct taattgcaat tgccgtttaa aatccgtttc cctcttatca gcagtatgga
     1501 gtatctcacc aattctctga aaaacaatag gctcatgacc attcttacgc tcaggcgtag
     1561 ccgtcaaacc gtaaagatac ttccctctaa actgagcaac aactttttca aacatcaagg
     1621 cagagacatg atgacactca tccacaatca tcatctcata ctcatccaaa agactttgac
     1681 tattttccaa cttaaataga gattgaatca taacgacatc aaccagttta ctcagccatt
     1741 tcttagtccc accgtactgt ccaacatagc cgattacctt ttcacgacct gatgccgtat
     1801 aacggatagc ctcctcctct tcgaaagtca aaaagcagtt taagcgatct agccattggt
     1861 ctaagagttg cttattatgg actagaataa ttgtttttgt tttccgttca gagataagag
     1921 cagcacctaa aacggtcttc ccaaaaccag tctccgcatg aagtaaacca ttttctttag
     1981 aagtcatatc tgacagggct aactcttgct caaaagtgag ttctccctta aattccacgc
     2041 taatagacct ttgtaccttt ctcctatctt ccacaactac ctgcttaaat ttatcttgca
     2101 atggatacag caaacctctt ggcaaccata aataatgatc ggattctcca aataaataca
     2161 ttctctcagg aatttgatag gttggctgtc gcatagcctg ctttaaataa aattcgggat
     2221 tagaaaatga agccatattt ttcaagaaaa acagtgtctt gggtgtcaca gacgattttt
     2281 caagttggat catattggat aagacgatct tcaacccctt gtccaattct tgcttgccta
     2341 actcttcttg gattaacagt gccactttag cagttgaaac cctctgaatt tcttgtagat
     2401 acctccattg gtcttcataa ggctgaaact gttcatccac aaagaccgtt cgcccttgat
     2461 ggtaagcttc tccttgaaaa ggcaaggcaa tcaaatttcc aaatcccccc ttaggaagga
     2521 catcctgatt tggaaacatg cgatcaaaag aatcaaagga cagttgcata ctttcctgca
     2581 ttgccagttc tatcagtttc tttccaaaca agcgagcctc tcgactcgga atcgcttcct
     2641 caaagaagaa ccaaatatgg agtccgtgac ccgaacgaga aatctctaaa tgggcttcca
     2701 tctggcgttc cctggctatt cttcgaatgg ttaaaccagc ttctttccaa tctccttcat
     2761 caaaatccag taccaaaaaa tgacagctat catctaagtg cataggaaag ataccgatag
     2821 ctgtctcccc acgaaaatga gatttcaaaa cggagttcgt caatgtctgg aaactccgtt
     2881 tttcaggtgg caactgcttc caaccataat cataggaagg aaaatactga attttccctt
     2941 gttcattgat aaaattctta gcataaacat cataacgtcc agcaaacacg gaggtaaaca
     3001 attgtaattt ttcttgcgtc gtcaagtgac tactttgaag ttggaacatc tcctcgaacc
     3061 gagagcgttc cataacaaac tgactcttgt ctttaagacg tttacacaag aaaaactcac
     3121 tatccccatc aaaagaagaa aagacatcaa gcacttctac cacaattcca tccaaagaca
     3181 caaaaacagc cataagagtc acctccttga ttcctatagg ctgattataa caagaatagc
     3241 tgaaattgta cacgaaaata aaatccgaat agcactcatt ttgtatgcga ctaatagtcc
     3301 atctcgctcc ggaatgtacg aggtaaatag agtttaaacg agcagtctat aaaattcaaa
     3361 aaacgcatat taccaaggtt gtt
//
LOCUS       DAYYYC010000089         3336 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.089, whole genome shotgun sequence.
ACCESSION   DAYYYC010000089 DAYYYC010000000
VERSION     DAYYYC010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3336
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.089"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(<1..99)
                     /locus_tag="ACHBV5_002047"
     CDS             complement(<1..99)
                     /locus_tag="ACHBV5_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HFM9967775.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRN"
     gene            complement(284..895)
                     /gene="rpsD"
                     /locus_tag="ACHBV5_002048"
     CDS             complement(284..895)
                     /gene="rpsD"
                     /locus_tag="ACHBV5_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFM9967776.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1090..2142)
                     /locus_tag="ACHBV5_002049"
     CDS             complement(1090..2142)
                     /locus_tag="ACHBV5_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFM9967777.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2139..2837)
                     /locus_tag="ACHBV5_002050"
     CDS             complement(2139..2837)
                     /locus_tag="ACHBV5_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFM9967778.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQI"
     gene            complement(3004..>3336)
                     /locus_tag="ACHBV5_002051"
     CDS             complement(3004..>3336)
                     /locus_tag="ACHBV5_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFM9967779.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
BASE COUNT          937 a          748 c          638 g         1013 t
ORIGIN      
        1 attacgtgag atttggaaaa cgtgtgatgc ttctgttata ctacctgttc gctcacaata
       61 agagagaact tttttacgaa aatctattga atatgccata aaagattata ccacattgtg
      121 tactattttt ggttcatttt actatatcac tttggactat atcggtctag ttatgtctca
      181 acgattatag ctggatacta agagaaatca aaaaagcact aagggagaac gtcccaaagt
      241 gcttaatatc aaggcctcaa agcctgtctt attcaataaa atattacaac atcttgttgt
      301 agaattcaac gacaagtgct tcgttgattt ctgggttgat ttcgtcgcgt tctggcaagc
      361 gagtcaatga accttccaac ttttcagcgt cgaatgatac gaatgctgga cgtccaagag
      421 tagcttctac tgcttcaagg attgctggaa ctttcaatga tttttcacga actgagatca
      481 cttgacctgg agttacgcgg tatgatggga tatcaacgcg tttcccgtca acaaggatgt
      541 gaccgtggtt tacgaattga cgagcttgac gacgagtagt cgcgagacca agacggtaaa
      601 caacattatc caaacgacgt tccaaaagaa gcataaagtt gaaacctagg attccacctt
      661 tgatttttgt agcttgtacg aacaagttac ggaattgttt ttcacctaca ccgtaagtga
      721 aacgaagttt ttgtttttca gccaattgca aaccatattc tgacaattta gaacggttgt
      781 ttggtccgtg ttgtcctggt acgtagttac gacgtgccaa ttctttacct gtacctgtaa
      841 gtgaaaggcc aaggcgacga gcttgtttcc aagatggtcc tgtataacgt gacatatgaa
      901 tgtcctcctg atataaataa tatttcggtg gaaatagtca cttagaaagc cctgattcgt
      961 gcagatgccc ttcgcctaaa cagccaaggt tacttgtcat aagacacctg ttgacgagct
     1021 tcatgctttc ctgctgatat ttcacacaaa atccatttta ccatgaatag ctggatttgt
     1081 aaaggggttt taggctttat tttcactacc agagaggttg agaacgaggg taaaggtact
     1141 tcctagaccg tactggctgc tgactgtgat ttccccaccc aattgatggg ccaattcacg
     1201 cgcaatcgca agtcctaatc catgaccacc tgtcttcatg ttacgcgaag tttcgacacg
     1261 ataaaggcgt ttgaaaatat tttccaaatc ctctggggca atgccctgcc cttcatcggt
     1321 cacactgatt gaaagctggt ccttctccag cttagccacc acttccagct tggttcctgg
     1381 agcagaatat ttaaaagcgt tatcgaccag attcaccaag atacgagaaa gcttagcata
     1441 atctccctca atccgggcag actctgggat tacctgcaag tggacatctc ttctctcctg
     1501 ctcaatcaaa aactgaaatt cactcatgca ctcaattaag agcttgtcca gaaaaatact
     1561 gtctttactg gtagtttcca cctgatttct agctgtgttt agggtcaaaa aattcaactc
     1621 ctcaaccagt ttattgagcc tctccgtctg gcgtccaatg gttgctagat aatgagcttg
     1681 ctccgactcc ttgataatcc catccaaaat cccttctacc gtcgcttgga tcgaagtgat
     1741 aggggtctta atatcatgcg acaactgggc aatcatcaag cccttttctc gttcgctttc
     1801 ttccaaggaa tcaaagctta cctgcaaatc atgggacatc tcattaaaag tttgccctaa
     1861 ttgctgaaat tctacaggac cttgaacctc caaatttgaa ggaaaatcct tggccgctac
     1921 ccgcttggca tgctccttga gtttgcccaa cgacgtaaag actggcaata ggagaaagag
     1981 actaatccca gcaccgacaa ggctggcaac gatggtcatc ccaagcaaaa agtaaatctc
     2041 gcctttcgca atcagcattt tttgaacagc ccaaaaaaca accaaaatgg ttaagagggt
     2101 tgaaataata tatccaacca aaatataact ttttagtttc atatttgtcc tctcggtttc
     2161 tctatcttat atcccaaccc ccaaactgtc ttaatagtgg gagtttggtc actactatat
     2221 tttgccagct cctgtcgaag agcatggata tgcacattca aggtattggt gtcatccacg
     2281 tagtcttctt tccagatctt ttcatagagg tctgtcttgg agaaaactcg ctctggattg
     2341 ctagctaaaa tccacagcaa ttcaaatgat ttaacagtta aatccagcat ttcttctcct
     2401 atttgaactt catgactact atgattcatt tttagattgc caagggaaat cagctctgtt
     2461 tcgcccccac gatgaaggcg gcgcaaaata ttgtggacac gcaaaaccag ctcacgtggg
     2521 ctaaaaggct tagcaataaa atcatctgct cccaagctca ggccgtaaat cttgtcctgt
     2581 tcactggtct tagcagtaat aaataggaaa ggctgctctg gtgataagta ttgaacctca
     2641 ctgattaaat cataaccatc catccgaggc atcatgacat ctgtgataat caaatcaatc
     2701 ggttttttct tgaacagctc tagcgcttcc agtccatcat gggctaccaa gacctgataa
     2761 cctgcctgaa ttaagtatct ctgatgaata tctgtgattt ctacctcgtc gtcaacgagt
     2821 aaaattgtct ttcccatctg tctctccttt gataaaaaca gtgctatact gctttaagta
     2881 taacactatt tttattgttt tacgatgatt ttaatctgct attgaaagaa agtcctgatt
     2941 gctgattgag ttgttaaact aatcttagtc agcccactat ccatcattta tttccttagc
     3001 tgattagttt tcttcttttt tgtttttcaa acctagacca ccgagtaaac ctgcaagcgc
     3061 aagcccaagg aaaccaatac ttgccattga tgtttgagtc tcaccagtat ttggtagcat
     3121 agctttatcc tctgacatca tcgtatcaga catcttgtta gcagaagcag ccatgttttc
     3181 acctgccatc gtgttggtag aacttgtcat ggtgtcagca ggcatgctat ctgtagtacc
     3241 tgtagcatga ttgtgattca tcggagtcac gccagaacca gagttagaag gtgataatga
     3301 accatttgct gtgtctgatg tttctttaac atttat
//
LOCUS       DAYYYC010000090         3144 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.090, whole genome shotgun sequence.
ACCESSION   DAYYYC010000090 DAYYYC010000000
VERSION     DAYYYC010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3144
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.090"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            170..2098
                     /gene="glgB"
                     /locus_tag="ACHBV5_002052"
     CDS             170..2098
                     /gene="glgB"
                     /locus_tag="ACHBV5_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HFM9967780.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRKDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATNITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            2088..>3144
                     /locus_tag="ACHBV5_002053"
     CDS             2088..>3144
                     /locus_tag="ACHBV5_002053"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HFM9967781.1"
                     /translation="MKNEMLALILAGGQGTRLAKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGIDSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLELGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAII"
BASE COUNT          954 a          541 c          722 g          927 t
ORIGIN      
        1 aaggtgtttt cgcaattttt tgaaaaaata ttgatttaca attgaacgag taagtgaact
       61 tgttgtagat tttcaaaata attaaagaag tatagtaatt tacttgaatc ttctctaaaa
      121 aggtagtata ataaaaacat agaaaacgct tacaggagaa agggagtata tggataatag
      181 agaagcatta aaaaccttta tgacgggtga aaatttttat ctccaacatt atctaggagc
      241 acatagggaa gaactaaatg gagagtatgg ctataccttc cgtgtttggg cacctaatgc
      301 tcaggctgtt cacttggttg gtgattttac caattggatt gaaaatcaga ttccaatggt
      361 aagaaaggac tttggggtct gggaagtctt taccaatatg gctcaagaag ggcatattta
      421 caaatatcat gtcacacgtc aaaatggtca tcaactgatg aagattgacc cttttgctgt
      481 caggtatgag gctcgtccag gaacaggggc aatcgtaaca gagcttcctg ataagaaatg
      541 gagggatgga ctttggctgg cacgaagaaa acgttggggc tttgctgaac gtcctgtcaa
      601 tatttacgag gttcatgctg gctcttggaa gagaaatcct gatggcagtc cttatagttt
      661 tgcccaattg aaagatgaac tcattcctta cctagttgag atgaactata ctcatattga
      721 gtttatgccc ttgatgtccc acccactagg tttgagttgg gggtaccagc ttatgggtta
      781 cttcgcttta gagcatgcct atggtagacc agaggagttt caagattttg tcgaggagtg
      841 tcatacccat aatattgggg ttattgtgga ctgggtacca ggtcacttta ccatcaatga
      901 tgatgcctta gcctattatg atgggacacc gacttttgaa taccaagacc ataataaggc
      961 tcataaccat ggttggggtg cccttaattt tgaccttgga aaaaatgaag tccagtcctt
     1021 cttaatttct tgcattaagc attggattga tgtctatcat ttggatggta ttcgtgtgga
     1081 tgctgttagc aacatgctct atttggacta tgatgatgct ccatggacac ctaataaaga
     1141 tggcggaaat ctcaactatg aaggttatta tttccttcag cgcttgaatg aggttattaa
     1201 gttagaatat ccagatgtga tgatgattgc agaagaaagt tcgtctgcga ccaatattac
     1261 gggaatgaaa gagattggtg gtctaggatt tgactacaaa tggaacatgg gctggatgaa
     1321 tgatatcctc cgtttctacg aagaagatcc gatctatcgt aagtatgact ttaacctggt
     1381 gactttcagc tttatgtatg ttttcaagga gaattatctc ttgccattct cgcacgatga
     1441 agtggttcat ggcaagaaga gtatgatgca taagatgtgg ggagatcgtt acaatcaatt
     1501 cgcaggcttg cgcaatctct atacgtacca aatttgtcac cctggtaaga aattgctctt
     1561 catgggtagc gaatacggtc aattcctaga atggaaatct gaagaacagt tggaatggtc
     1621 taacctagaa gacccaatga atgctaagat gaagtatttc acttctcagc taaaccagtt
     1681 ttacaaagat catcgctgtc tgtgggaaat tgataccagc tatgatggta ttgaaatcat
     1741 tgatgcggat aatcgagacc agagtgttct ttcctttatt cgtaagggta aaaagggaga
     1801 aatgttagtc tgtatcttta atatggtacc tgttgagcgg aaagatttta caatcggact
     1861 acccgttgca ggaatttacg aagaagtatg gaatactgag ttggaagagt ggggaggcgt
     1921 ttggaaagaa cataatcaaa ctgttcaaac gcaagaagga ctatggaaag attatgagca
     1981 gaccttaacc tttaccctac cggctatggg agcaagtgta tggaaaatca aacgtcgctt
     2041 gaaatctact aaaaccgtca caaataaaaa ccaaaaagga gtagaaaatg aaaaatgaaa
     2101 tgttagcttt gattcttgct ggtgggcaag gaactcgtct cgctaaactc actcaaagca
     2161 tcgcaaaacc agctgtgcaa tttggtgggc gctaccgtat cattgacttt gccctatcaa
     2221 actgtgccaa ctcagggatt cacaatgttg gggtcgttac acagtatcaa ccacttgctc
     2281 tcaacaacca tattgggaat ggttcaagct ggggactaga cggtattgat tcaggtgtct
     2341 ctattcttca accttattct gcaagtgaag gaaatcgttg gtttgagggg actagtcacg
     2401 ctatttacca aaatatcgac tatatcgaca gtgtcaatcc tgagtatgtc ttgattttgt
     2461 ctggggatca catctacaaa atggactatg atgatatgct ccagtctcat aaggataata
     2521 atgccagctt gacagtagca gttttagacg tccctcttaa agaagcaagc cgttttggta
     2581 tcatgaacac agatgctaac aatcgtattg ttgaatttga agaaaaacca gctcaaccta
     2641 aatctacaaa agcttctatg ggaatctaca tttttgattg gcaacgcctt cgtaatatgt
     2701 tagtcgctgc tgaaaagagc aaggttggca tgtcagactt tggtaaaaat gtcattccaa
     2761 attaccttga gttaggtgaa agtgtttatg cttacgaatt tagtggttat tggaaagatg
     2821 ttggtactat tgagtcactt tgggaagcga acatggagta tatttctcca gaaaatgcct
     2881 tggatagtcg taaccgtcaa tggaagattt actcaagaaa cttgatttca ccaccaaact
     2941 tcctcggggc aaatgctcat gtggaagact cattagttgt agacggatgt ttcgttgatg
     3001 gaactgttaa acattctatc ctttcaacag gcgcgcaagt tcgcgaagga gcggaagtcc
     3061 ttgattcagt tatcatgagt ggagctatca ttggtcaagg agctaagatt aaacgtgcca
     3121 ttattggtga aggtgcgatt attt
//
LOCUS       DAYYYC010000091         3030 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.091, whole genome shotgun sequence.
ACCESSION   DAYYYC010000091 DAYYYC010000000
VERSION     DAYYYC010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3030
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.091"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..763
                     /locus_tag="ACHBV5_002054"
     CDS             <1..763
                     /locus_tag="ACHBV5_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFM9967782.1"
                     /translation="KDSGSIITNNPIWESFNLLNVIKKFDFPFIVKNNIDCMAIGQYL
                     FNPHNTPDNFIFLHAGLGIYTSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKG
                     CLQTYISDAWLIKHAQLLFKNSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQID
                     KGVNLLATSIANLLLINPADKIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIE
                     ILPYNKHRGSIGACALAIVAFFIEHSNVLQDIISP"
     gene            1774..2058
                     /locus_tag="ACHBV5_002055"
     CDS             1774..2058
                     /locus_tag="ACHBV5_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967783.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDIEKL
                     LDSKELTHFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            2051..2608
                     /locus_tag="ACHBV5_002056"
     CDS             2051..2608
                     /locus_tag="ACHBV5_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6036 family nucleotidyltransferase"
                     /protein_id="HFM9967784.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVGGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNTHEELWLNNHVANMNKQPPLSLCESLYSFENLTVL
                     VVPIEYVLGMKMMSIREQDLKDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVLLEG
                     FSYAYGMDWLEKFFKENQDKLREFY"
BASE COUNT         1118 a          528 c          446 g          938 t
ORIGIN      
        1 caaagactcc ggaagcatca ttacaaacaa ccccatatgg gaatcattta atttattaaa
       61 tgtaattaaa aaattcgatt tcccttttat tgtaaaaaat aatatcgatt gtatggctat
      121 aggacaatac ctttttaacc cacacaatac ccccgataac tttattttcc tacacgctgg
      181 attaggtatt tacacttcct ttttcacaaa agaaaaaata ggagcctcta aaaatcctta
      241 tatcggagaa attggacaca ccattgtcga attaaatggg caatattgtg aatgcggaaa
      301 aaaaggttgt ttacaaacat atatttcgga tgcttggtta atcaaacatg cccaattatt
      361 atttaaaaat tctcaactaa ctgtactaaa aagccttgta aagactgaaa aagacattca
      421 tttagatacc cttttaacag cttacaactt aggcgactct gctttacgcc aacaaattga
      481 taaaggagtc aatttattgg ccacttctat tgcaaatctt ctcctcatca atcctgctga
      541 taaaatctat atcaacagtc aattgcttaa ttatcaacct ttcactcatg aagtcaggga
      601 taaaatccaa gatcagctcc acttcgttcc ctttactcgt aatatagaaa ttgaaatttt
      661 accttacaac aaacatcgtg gaagtatagg agcttgtgca ttagctatcg ttgctttttt
      721 catagagcat agcaatgtat tacaagatat tatttcacct taatatatta gaaatctata
      781 gacctgttta aatcaactat aacctgtagt aaatatctcg tatttagaca atatgaaaac
      841 aagacgactt ccatatagga aaccgccttc tcgctatgct gcatgaaact gtaaaaatag
      901 atgaaagtga tagcggtagt caaatcaaga ggcatcataa ctctaaaaag tcacaatata
      961 taagttcatc ctcagaaaaa tatcattcta attattgaaa tgcctacatg aaaagaaacg
     1021 ttaaatgctc ataaaacaag gaatacaggt atcaaaactg tgacaaaaca agtccctaaa
     1081 tttactaaag acactactca actttacacc tgtaaatggt tgttgtataa taaagttaca
     1141 aagatgtacg accacactgt tgtaaatcat agtgttcgcg aatatattac tgatagcatt
     1201 tctacaaata caagtaaagg gattggatga gattcaaacg aaatatgtca gtgttttggc
     1261 attcctagcc ttcatatcat ttaaagaatt gtatagataa aatttttccc aatacagaca
     1321 ctcgtaacaa ctgcttcatt tttctaccaa catatttagg aacaggataa gatacaagag
     1381 gatcaatcca taaatcagtt ctataccaat ctaagacaaa taagctaaaa aaacgattga
     1441 taataagcaa atagattcca aattttctct atctgctcat tttaataaac aatactagtg
     1501 taactatcct tccagtcaga agcttgtcaa atcacaccga aaattcttct aaaatttatc
     1561 tcgttaggca atcaagcaaa aactcaacga tagtacaaac attatcatac aggattgact
     1621 tcctaaatta tatactttag taaggttttt ggataagaaa aaaggttcat tttacatttc
     1681 taaacactct tttctaatac gagataatta aaaaaactac atttttaaat ataaactaca
     1741 ataaaataaa ctaaatgcca taggagaaag acaatggatt ggtacgatta tatgatacag
     1801 gcatccaaac aatcacaatt caacgcaagc cattggtttc gctatttgcg aaaagttatt
     1861 tttgaagact attcttattt aacaaaccaa gatatagaaa agttgctaga ctccaaagaa
     1921 ctaacccatt ttcaaaaaat tagcttgaag tatgcctttc aagagcatac tccaactcat
     1981 aaatatgtga tttcattaaa taaacctgct aagttaacca atgttcaaaa attgatggag
     2041 aaatacaagc atggataaaa tgaaaccggt cttccaagca ctaaataagg aattaattca
     2101 ggaaaatctg actttaacaa ttatctgtgt cggtggttat gtcttagaat atcatggttt
     2161 gcgtgccaca caagatgttg atgcttttta tgaccaaaat cagaaaatca atgaaattat
     2221 tgctcgtgta ggaaaacagt ttaatcttaa cacccacgaa gagttatggc tcaacaatca
     2281 tgttgcaaat atgaacaaac aacctccctt aagtttatgc gaatccttgt actcatttga
     2341 gaatctgacc gttttagtag tccctattga gtatgtgtta ggaatgaaga tgatgagtat
     2401 cagagagcag gatttgaaag atattggtgc aattattaaa tacaaaaact ttcattcacc
     2461 attcgatacc tttaaatatt taaaagacat gggatttgat actattgacc tctctgttct
     2521 attagaaggt tttagttatg cttatggtat ggattggtta gaaaaatttt ttaaagaaaa
     2581 tcaagataaa cttcgcgaat tttattaaca gtatcaaaca agatgattgt caattagcca
     2641 gtcgtcttgt ttttatgatg aaatgaaata aaatcggaac aaatcactta gagaattcca
     2701 gtcaatttct agcactgttt gagacgtttc agcggactat agcaaaatga aataagaata
     2761 ggacaaatcg atcaggacag tcaaatcgat ttctaagaat gttttagaag taaaggtgta
     2821 ctattctact ttcaatctat tatatttcag attcggtcca ctattccttc ccaaaaacat
     2881 tgcatattgc gccgaaggaa ttgctcatac tatcccaagc acaaaaccct cagtcgtttg
     2941 accgagggtt cctttttatt attcaagaac ttgaggctct ataatatttg tagtgggtaa
     3001 atcccctatg gatattatgg agcctatttt
//
LOCUS       DAYYYC010000092         2991 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.092, whole genome shotgun sequence.
ACCESSION   DAYYYC010000092 DAYYYC010000000
VERSION     DAYYYC010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2991
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.092"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..408
                     /locus_tag="ACHBV5_002057"
     CDS             <1..408
                     /locus_tag="ACHBV5_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM9967785.1"
                     /translation="FYRPTFRMHLTNKEILDKLLSYSEDLKHHYQLYQLLLFHFQNKE
                     PEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIINALQLPYSNAKLEATNNLIKLIKH
                     NAFGFRNFENFKKRIFIALNIKKERTKFVLSRS"
     gene            complement(596..2158)
                     /gene="guaA"
                     /locus_tag="ACHBV5_002058"
     CDS             complement(596..2158)
                     /gene="guaA"
                     /locus_tag="ACHBV5_002058"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFM9967786.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2300..>2991
                     /locus_tag="ACHBV5_002059"
     CDS             2300..>2991
                     /locus_tag="ACHBV5_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFM9967787.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERHVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLE"
BASE COUNT          912 a          635 c          565 g          879 t
ORIGIN      
        1 ttttatcgtc ctacttttcg tatgcattta accaataaag agattttaga caagcttttg
       61 agctattcgg aagacttgaa acaccactat cagctctatc agctcttgct ttttcacttc
      121 cagaataagg aaccagagaa atttttcgga cttattgagg acaatctgaa gcaggttcat
      181 cctatttttc agactgtctt taaaaccttc ctcaaagata aagaaaagat tatcaacgcc
      241 cttcaactac cctattcaaa cgccaaattg gaagcgacca ataatctcat caaacttatc
      301 aagcacaatg cctttggttt tcggaacttt gaaaacttca aaaaacggat ttttatcgct
      361 ctgaatatca aaaaagaaag gacgaaattt gtcctttctc gatcttagct tttcttcaac
      421 ccactacagt tgacaaagag cctgaaaact acggtctaat tttttgtcca aatgtaaacc
      481 acttggaact attattcaat ttattctttt tagcaaatgt tcccgtttta atcccagtta
      541 cagtttttaa tcctttgtaa ccgttgattt tacaaagctt ttaatttttt tgcgattact
      601 cccactcaac tgttgcaggt ggtttacttg taatatcgta gacgatacgg ttaacatgat
      661 ccacttcatt tacgatacgt actgagattt tttgaagtac ttcccatgga attttggcaa
      721 aatcagcagt cataccatcg atagaagtga tagcacggat tgcaatcgtg tagtcatacg
      781 tacgaccgtc acccataaca ccgactgaac gaacgcctgt gttaacagtg aagtattgcc
      841 aaatatcgcg gtcaagtcca gctttagcga tttcttcacg aagaatagcg tctgattcac
      901 gaacggtttc aagtttctct tcagtgattt cacccatgac acggatagca agtcctggtc
      961 ctgggaatgg ttggcgccat acgatatggt ctggcatacc aagctctgta ccaagagcac
     1021 gaacttcatc cttgtaaaga gtattgagtg gttcaatcaa ttcaaactgc atatcttctg
     1081 gaagaccacc cacgttgtgg tgtgacttga tagtttgagc tgtatccgta ccagactcga
     1141 taacatctgt atataaagta ccttgagcaa ggaatttcac atctttgagc ttgcttgctt
     1201 cgtcatcgaa tacatagaca aactcgttac cgatgatttt acgtttttgt tcagggtcag
     1261 aaacgccagc aagtttgtca aggaaacgtt tagcagcgtc tgctttgacg atattcaaac
     1321 caaacttacc accgagcatg tccataactt gatcagcttc gcctttacga agaagaccgt
     1381 ggtccacgaa gatacagatc aattgatcgc caatcgcttt ttggagaaga accccaacga
     1441 cagatgagtc aacaccacct gatagaccaa gaaggacacg tttatcaccg acggtttcac
     1501 gaattttttt gatctgcatg tcaatgaaat tatccattga ccagtcacct ttagccttac
     1561 aaatgttaag ggcaaagtta cgaaggatat catttccgta tacagaatga cgaacttctg
     1621 ggtggaattg gataccgtaa atgtgtttat ctgggttttc gatggctgcg tatgggcagt
     1681 cagctgatgt acctgtacga acaaagtcag caggaatctc agtaaccgca tcaccatggc
     1741 tcatcaaaac agtctgttca tcaggtgttg attcaaaaag cgctgatggt gtgtgagtta
     1801 gggttgattg accgtattca cgatttccag catcacctgc aggaacaact tttcctccaa
     1861 gtttatgggt caataactgc ataccataac agattcccaa aattggaatt ccgagttcga
     1921 agatttctgg gtcaatatca aatgaaccat cttcatatac agaatttgga ccacctgata
     1981 gaataattcc tacaggattg acttcacgaa cttcagcagc tgaaatttta tggcttttta
     2041 gttctgaaaa aacaccaatc tcacggatac ggcgtgaaat cagctggttg tactggctac
     2101 catagtccaa tacgatgatt ttttctacat cttgcaaatc agttgaaatg ttgctcatct
     2161 ttttcctttc tcaaaagaaa tatcttttct caatattcta tcacaaataa gggcgaatta
     2221 ccaactaaac aaggcgaagt ttgacttttt ctagtttatt ggggtacaat agagaaaaga
     2281 tagaaatgaa gtgaaaaata tgctacctgc ttatatgaaa atccatgatc agataaaaaa
     2341 ggatattgac gagcaccgtt gggctattgg tgagaggctt cccagtgaaa gagatttagc
     2401 tgagcagttt gcggtcagtc gcatgaccct ccgccaagcc gtatctctat tagtcgaaga
     2461 aggcgtctta gagcgccatg taggaagcgg cacctttgtt tccagtactc gagtacaaga
     2521 aaagatgcga gggacaacca gttttactga aattgtcaaa tcccaaggta aagttccctc
     2581 tagccagctc atttcctaca aaaaaaccat tcccaatgag caagaagttg ccaagctagg
     2641 aatttttcca acggacaata ttatccgaat ggagcgggtc cgctatgccg accaagttcc
     2701 cctagtttat gaagttgctt ctattcctga aaaattcatt aaggacttta aaaaagaaga
     2761 aatcaccagt catttcttcc aaaccttgca aaaacatggc tatcgtatcg gcaaatctca
     2821 acagaccatc tatgctcgcc ttgctaaaga aaagattgcc cactatttgg aagttgaaaa
     2881 aggacatgct attcttggat tgacccaggt ttcctaccta gaagatggta ctgcttttga
     2941 atacgtaaaa agtcaatatg taggcgaacg ctttgaattt tatcttgaaa a
//
LOCUS       DAYYYC010000093         2736 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.093, whole genome shotgun sequence.
ACCESSION   DAYYYC010000093 DAYYYC010000000
VERSION     DAYYYC010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2736
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.093"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..641
                     /locus_tag="ACHBV5_002060"
     CDS             <1..641
                     /locus_tag="ACHBV5_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CatA-like O-acetyltransferase"
                     /protein_id="HFM9967788.1"
                     /translation="DGIFHLSEWKRNEEFDFFNKMDVPYLSMSSRIEVTQAINFHKKH
                     SISLYAIISWCVMSAINSIPELLMDTDGKIVWQYNQRGCSFTTLTSEDKLNFSSFTMG
                     DNLIEFVSAFNINKQKAEEGQKPNIDKNNIAYLSCVPWIDFLHVSTPMNLSKIDTVPR
                     ITWGKVIQENQRYFCTVNLQINHGMGDGLHVSNFFVLLQRFVNKINEYFQKK"
     gene            709..2346
                     /gene="metG"
                     /locus_tag="ACHBV5_002061"
     CDS             709..2346
                     /gene="metG"
                     /locus_tag="ACHBV5_002061"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFM9967789.1"
                     /translation="MSIFIGGAWPYANGSLHIGHAAALLPGDILARYYRQKGEEVLYV
                     SGSDCNGTPISIRAKKENKSVKEIADFYHKEFKETFEKLGFTYDLYSRTDSPLHHEIV
                     QELFLQLYEKKFLYTKKIKQLYCTFDNQFLPDRFVEGKCPNCGTHSRGDQCDNCSAIL
                     DPIDLVDKRCSICSNEPEVRETEHFYYVFSEFQNLLETYLNDAEETVRWRKNAINLTK
                     RYLREGLPDRAVTRDLPNGIPVPIDGFRDKKIYVWFEAVAGYYTASVDWAQKLQNNIT
                     DFWNNRTKSYYVHGKDNIPFHTIIWPAILSGLEIEPLPEYIISSEYLTLENKKISTSN
                     NWAIWLNDIIKKYDADSIRYFLTINAPEMKDANFSWREFIYSHNSELLGSYGNFINRT
                     LKFIEKYFESEIPTKYLEGEILYNLKELYTTVGNLVESGHMKQALEEIFEYIRSANKF
                     YDDMKPWALRESDIEKCKEVLATCVIIILNLGQMLNPFIPFSGKKIEDMFKTKLNTWN
                     YISNLPNKLSDVSMLFDRIDLKKIDEEVLELQQTSSR"
     gene            2447..>2736
                     /locus_tag="ACHBV5_002062"
     CDS             2447..>2736
                     /locus_tag="ACHBV5_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HFM9967790.1"
                     /translation="MNNLTLLKEYNFRDLGNHLTQTGQKIKPKTLFRSSKLFGISKID
                     VDLLQSYGITKVIDFRSANEIKKAPDPDIKNIKNIVIPIFYNDDSELTEFPI"
BASE COUNT         1023 a          360 c          478 g          875 t
ORIGIN      
        1 gggatggaat ttttcattta tcagagtgga aaaggaatga agaatttgac tttttcaata
       61 aaatggatgt tccttattta tctatgagtt cacgaataga agtaacgcag gctatcaatt
      121 ttcataaaaa acattcgata tcactttatg ccataatatc gtggtgtgtt atgagtgcaa
      181 taaattctat tccagaatta ctaatggata ccgacggaaa gattgtctgg caatacaatc
      241 aaagaggttg ttctttcact acccttacat cggaagataa gcttaatttt tcttcattta
      301 cgatgggaga taatttaatt gaatttgttt ctgcgttcaa cataaataaa cagaaggcag
      361 aagaagggca aaaaccaaat attgacaaga ataacattgc ttatctttct tgtgttccat
      421 ggattgattt tttacatgta agcactccta tgaatctttc aaaaattgat acagttcctc
      481 gaataacgtg gggaaaagtt attcaagaga accaaagata tttttgtaca gtgaatttac
      541 aaattaatca tggaatggga gatggattac acgtatctaa tttttttgtg ttattgcaaa
      601 ggtttgtaaa taaaataaat gaatattttc aaaaaaagta atgattgaaa agatattgca
      661 tttaaataat gttataataa aaataaagaa tttaaggaga aatacaatat gtcaattttt
      721 attggaggag catggccata tgcaaacggt tcgttacata ttggtcacgc ggcagcgctt
      781 ttaccggggg atattcttgc aagatactat cgtcagaagg gagaggaagt tttatatgtt
      841 tctggaagtg attgtaatgg aacccctatt tctatcagag ctaaaaaaga aaataagtct
      901 gtgaaagaaa ttgctgattt ttatcataag gaatttaaag aaacttttga aaaattaggt
      961 tttacatatg acttgtactc gcgaacagat tctccactac atcatgagat agtacaagaa
     1021 ttatttttgc aattatacga gaagaaattt ttgtatacaa aaaaaattaa acaactctat
     1081 tgtacatttg ataatcaatt cttacctgat aggttcgttg aaggaaaatg cccgaattgt
     1141 ggaacccatt caagaggaga tcaatgtgat aattgctcag caattttaga tcctatagat
     1201 ttagttgata aaagatgttc tatttgttcc aatgaaccag aagttcgtga gacagaacac
     1261 ttttattatg tttttagtga gtttcaaaat ttgttagaga cttacttaaa tgatgctgaa
     1321 gaaacagtga gatggcgaaa aaatgcaata aatctaacta aaaggtattt acgggaaggt
     1381 ttacctgatc gagctgttac tcgtgatcta ccaaatggga ttccagttcc cattgatggt
     1441 tttagagata aaaaaatata tgtctggttt gaagcggtag caggttacta cacagcaagt
     1501 gttgattggg cgcaaaaact tcaaaataat attactgatt tttggaacaa tcggacaaag
     1561 tcatattatg ttcatggaaa agataacatc ccatttcata ctattatttg gccggcaata
     1621 ctctcaggtt tagaaataga gcctcttcca gagtatatta tttctagtga atatttaacg
     1681 ttagaaaaca aaaaaatatc aacaagtaat aattgggcta tatggcttaa cgatatcata
     1741 aaaaaatatg atgctgattc aatccgatac ttcctaacaa taaatgctcc tgagatgaaa
     1801 gatgcaaatt tttcttggag agaatttatt tatagtcata actcagaatt attaggatcg
     1861 tacggtaatt ttatcaatag gactctaaag tttattgaaa agtattttga atctgaaata
     1921 cccactaaat atctcgaagg agaaatttta tataatttga aagaattata tacaacagta
     1981 ggtaatttag ttgagagcgg gcatatgaaa caggcattag aagaaatttt tgaatatatt
     2041 agatcggcta ataaattcta tgatgatatg aaaccgtggg cattgcgaga gtccgatatt
     2101 gaaaaatgta aagaagtctt agctacttgt gtaatcatta tacttaattt aggacaaatg
     2161 ttaaatccat tcattccttt ttctggtaaa aagattgagg atatgtttaa aacaaagcta
     2221 aatacttgga attatatttc aaaccttcct aacaagctat cagatgtatc aatgttgttt
     2281 gataggattg atttgaaaaa aattgacgag gaagttttag aattgcaaca aacatccagt
     2341 agataattca aaaatactcg aaagtagcct tttttaattt aaattaacaa ccggagatgt
     2401 tgaataaaat aaagatggtt ttttgagcat attatggaga aaagcattga ataatctaac
     2461 tttactaaaa gaatataatt ttagagatct tggaaaccac ctcactcaaa caggacaaaa
     2521 aataaaacct aaaacattat tccgttcaag taaactattt ggaatctcta aaattgatgt
     2581 cgatttgtta cagagctatg gaataacaaa agtcattgac tttcgatcag cgaatgaaat
     2641 aaaaaaagct ccagatccag atataaaaaa tataaaaaat atagtaattc caatattcta
     2701 taatgatgat tcagagttga cagaattccc aataga
//
LOCUS       DAYYYC010000094         2646 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.094, whole genome shotgun sequence.
ACCESSION   DAYYYC010000094 DAYYYC010000000
VERSION     DAYYYC010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.094"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            164..352
                     /gene="rpmB"
                     /locus_tag="ACHBV5_002063"
     CDS             164..352
                     /gene="rpmB"
                     /locus_tag="ACHBV5_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFM9967791.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            509..874
                     /locus_tag="ACHBV5_002064"
     CDS             509..874
                     /locus_tag="ACHBV5_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFM9967792.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            877..2544
                     /locus_tag="ACHBV5_002065"
     CDS             877..2544
                     /locus_tag="ACHBV5_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFM9967793.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
BASE COUNT          863 a          481 c          593 g          709 t
ORIGIN      
        1 gacattttca cgttcgattt actaaagaca ttatcacatt cgaatcacaa cacaaataaa
       61 aaatcttcca attcccttgc aaaaaacaag aaagtgtgat aacatagtac ggtatgtggt
      121 gctagcacat ccgctatatt agatctaata ggaggaaaac acaatggcta aagtatgtta
      181 ctttacaggt cgtaagactg tatcaggaaa caaccgttca cacgcgatga accaaacaaa
      241 acgtgccgta aaaccaaacc ttcaaaaagt tactgttctt atcgatggta aacctaaaaa
      301 agtttgggct tcagctcgtg ctttgaaatc aggtaaagtt gaacgcgttt aataataaaa
      361 gcaaaggaga ccttagggtc ttttttcttt tattgtgggt ataacatcgt ttgaaaaata
      421 gagtaaatat ccgctgatac atcattctgc ttttacactt gggctgaaat atgataaaat
      481 agagtatcaa ctagttgagg taaaaaggat gactgtaaaa attaatacaa aagatggtca
      541 aatcgaacta acagatgaag tgattgcaac cgtcgtaggt ggagcagcaa ctgagatttt
      601 tggtgtggtc ggtatggcta gtaaaaatgc cctcaaagat aatttccaag ccctgctagg
      661 taaggaaaat tattctaaag gtgtcgtcgt aaaggcagcc gaagatggca gtattgcagt
      721 tgatgtatat accgtgttaa gctacggaac aaagattagt gaagtgtcaa aaaacattca
      781 agagcgtgtt gcctttagct tggaaaacca gcttggaatt actgctcaga ctgtaaatgt
      841 ctacattcaa aatatcaaag ttgtaggaga ataaccgtgt caaagattac tactagctta
      901 tttcaagaaa tggtgcaggc tgcatcaact cgcttgaata agcaagctga atatgtcaat
      961 tcattaaacg tctttccagt tccagatgga gatactggga caaatatggg aatgaccatt
     1021 gaaaatggtg ctaaagaagt tgcagacaag ccagcttcta cagttggaga agtagcgagc
     1081 attcttgcca aagggctttt gatgggtgcg cgtgggaact caggagtgat tacatctcag
     1141 cttttccgtg gattttccca agctatcaag gataaagacg agttaacagg tcaagacttg
     1201 gctctggcct tccaatcagg tgtggaagtt gcctataagg cagtgatgaa acctgttgaa
     1261 ggaacgattt tgacagtttc tcgtggagct gctatcggtg ctaagaaaaa agctgagcaa
     1321 acagatgata ctgttgaagt catgcgcgca gccttggaag gtgctaaaac agctctagct
     1381 aaaacaccag acatgcttcc agtattgaaa gaagttggcg ttgtggactc aggtggtcaa
     1441 ggattggtct tcatctacga aggtttcctt tcagccctta ctggcgaata tattgcatct
     1501 gaggactttg tagcgactcc tgccaacatg agtgagatga tcaatgtaga gcatcataag
     1561 tctgtagctg gtcacgtagc gactgaggac atcacgtttg gttactgtac tgaaatcatg
     1621 gtagctctta agcaaggtcc aacctatgct aaagattttg actacgatga attccgtaac
     1681 tacttggatg agcttgggga ttctctcctc gttgttaacg atgatgaaat tgtcaaagtc
     1741 catgttcata cagaagatcc aggacttgtt atgcaagaag gtctcaaata tggtagcttg
     1801 gtcaaggtaa aagttgacaa tatgcgtaac caacacgaag cacaggttga gaaagaagct
     1861 actcaagtta tcaagtcggc tgaagaaaaa gagtatgctt tgattgctgt ggtggctggt
     1921 aaaggtctag cagatatctt ctgttctcaa ggcgtggatt atgttatcga aggcggtcaa
     1981 accatgaacc cttcaacaga agactttatc aaggctgttg aacaggtcaa tgcccgtaac
     2041 atcatcttct tgccaaacaa caagaacatc ttcatggcag ctcaatctgc ggcagaagtt
     2101 ttggagcaac cagcagtagt ggtagaggct cgcactcttc ctcaaggtat gacaagtctt
     2161 cttgcctttg atccaagcaa gtccattgaa gaaaaccaag agcgtatgac agctgctctt
     2221 agcgatgtcg ttagcggaag cgtcacaaca gccgtgcgtg atacaacgat cgatggctta
     2281 gaaatccatg aaaacgataa tctaggtatg gtggatggaa aaattcttgt gtcaaaccct
     2341 gatatgcacc aaacattgac tgaaaccttg aaacatatgt tggatgaaga cagtgaaatc
     2401 gtaaccttct atgtcggtga agacggaagc gaagaacttg ccaatgaaat cgctcaagaa
     2461 atcgtagaag aattcgaaga cgttgaagtc gagattcacc aaggtcaaca acctgtttac
     2521 ccatacctat ttagtgtgga ataagattaa tgaaggactg agaaatcagt tcttttttct
     2581 tttttagtaa atgaaatcgg tatcttttta ataaaaacaa aaataacatt cataaataaa
     2641 cgttaa
//
LOCUS       DAYYYC010000095         2459 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.095, whole genome shotgun sequence.
ACCESSION   DAYYYC010000095 DAYYYC010000000
VERSION     DAYYYC010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.095"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            1..618
                     /locus_tag="ACHBV5_002066"
                     /pseudo
     CDS             1..618
                     /locus_tag="ACHBV5_002066"
                     /inference="COORDINATES: protein motif:HMM:NF021048.4"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            615..1793
                     /locus_tag="ACHBV5_002067"
     CDS             615..1793
                     /locus_tag="ACHBV5_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000217311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HFM9967794.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     "
     gene            1962..2375
                     /locus_tag="ACHBV5_002068"
                     /pseudo
     CDS             1962..2375
                     /locus_tag="ACHBV5_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251597.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
BASE COUNT          937 a          351 c          439 g          732 t
ORIGIN      
        1 aaattagcta agaaatattc tgataactta aacatcaaag ttcaagagag agttcgtgaa
       61 atggcaaatg ataataagag ccattatttg atatacagag ttttaggtat ttcatttgaa
      121 gaaggagaaa atatcgattt gtatcaaaat aaaggtcgtt ttttatacaa atatgctggt
      181 tcatttttag aagaagctgc agtactatcc tttaacgaaa aatttggtac agaaaatact
      241 taaaaagtta acattcctaa ttctgaaagt acaaaaccta agacttttga aattgattgt
      301 ttagtcggag aaaaacacgc atacgaaata aaatggtggg atgcaactac agatggagac
      361 catataacta aagaacacac tagaataaaa gttattcata acaaaggata tataccaatt
      421 cggttaatgt tctactatcc aaatagaact caagctataa aaattcagca aactttagaa
      481 acattgtata acggtattgg agggaaatat tattatggag attctgcctg ggaacattta
      541 agagcagtga ccggtattga tttacttagt attctaacag atattgcaaa taaaaaaaca
      601 ggggtaaaat caaaatgaca gtattaaaag gagataactt agaaatatta aaaactattg
      661 aatcctcaag tattgattta atctatatgg accctccttt ctttacacag aaaacccaaa
      721 aattatctaa taacaaaaat attatgtatt cattcgaaga tacgtggact tcgattgagg
      781 attacaaaga atttttgtct gtaagattag aagaatgcaa aagagtgcta aaaaatagtg
      841 gcagtatttt cgttcattgt gataaaattg caaatcatca tattagatta attttagata
      901 atatctttgg agcagatatg tttcaaagcg aaattatatg gaactataaa cgatggtcta
      961 attcaaaaaa gggattattg aacaatcatc aaaacattta cttttattca aagtcaaaag
     1021 attttaaatt taatacaatt tttacagagt attcttctac tacaaatatc gaccaaatac
     1081 tagtggaacg aaaacgagat ggaaactcta aaactatata taaagttgat aataatggta
     1141 actatattct agcaaaagag aaaaatggag ttcccctttc agatgtttgg aatataccat
     1201 ttcttaatcc aaaagctaaa gaaagagtag gttatcctac acaaaaacct attctgttat
     1261 tagaacaaat tataaagatt gctactgata aaaatgatat agttttagac ccgttctgtg
     1321 gaagcggaac tactttagta gcctccaaga ttttgaatag aaattatatg gggattgatt
     1381 tatctgagga agctatcaat ataactcagc aacgtctgga aaatgttata aaaacaagtt
     1441 caaatttatt gaataaagga atcgaagcat atagaaccaa aactgaggaa gaggaaaaca
     1501 ttcttaaatt attacaggca aaaattgttc aaagaaataa aggaattgat ggttttttac
     1561 ctaaacattt tcaaaaaaaa ccgataccta taaaaattca aaaaaataat gaatgtctga
     1621 atgagagtat ctctttatta cagaatgcta taaactccaa aaaacttgat tttggagtag
     1681 ttataaaaac tcattcagat aatttattat ttgattttga tacgattcct gaaaatataa
     1741 tagtagttga ccattttgaa cttacaatcg aaaaatggtt aagtaaaagt taacagttac
     1801 tatagtttgc aaattattta cagaaagaac aagaattcct aggagattat tctggctatg
     1861 ttcattgtga catgttgcgg cagtaactta ggactttagt cctctagttc tgcctatgcg
     1921 atagcagtcc aaagtttagg agtaaggcga cgctaagctt ggtaaactgc gaacagctag
     1981 aagcttatcg tcaactggaa gaagctgcac ttgttggatg ttgggcgcat gtgagaagga
     2041 agttttttga agcgaccccc aagcaagcag ataaatcatc cttaggagct aaaggtttag
     2101 cttattgtga tcagttattt tccttggaaa gagactggga ggctttgcca gctgatgaac
     2161 gactacagaa acgtcaagaa catctccaac ccctaatgga agacttcttt gcttggtgcc
     2221 gccgtcagtc agttttagca ggttcaaaac taggaagggc aattgaatac agcctcaagt
     2281 ataaagaaac ctttaagacc attttaaaag acggacatct ggtcctttcc aataatctag
     2341 ctgaacgcgc cattaaatca ttggttatgg gacggagtaa aagagtccag tggactcttt
     2401 tagcctgagc tcagtttaaa aaagcgaggg tggttatttt ctcaaagttt tgaaggagc
//
LOCUS       DAYYYC010000096         2104 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.096, whole genome shotgun sequence.
ACCESSION   DAYYYC010000096 DAYYYC010000000
VERSION     DAYYYC010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2104
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.096"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            85..624
                     /locus_tag="ACHBV5_002069"
     CDS             85..624
                     /locus_tag="ACHBV5_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFM9967795.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            691..1101
                     /locus_tag="ACHBV5_002070"
     CDS             691..1101
                     /locus_tag="ACHBV5_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HFM9967796.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            1217..>2104
                     /gene="pavB"
                     /locus_tag="ACHBV5_002071"
     CDS             1217..>2104
                     /gene="pavB"
                     /locus_tag="ACHBV5_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HFM9967797.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLV"
BASE COUNT          639 a          404 c          467 g          594 t
ORIGIN      
        1 tctatacggc aaggcgacgt tgacgcggtt tgaagagatt ttcgaagagt ataagaaaaa
       61 atcagtcccc taaaggagta gattatgaag ttattgtcta tcgcaatttc tagctataat
      121 gcagcagcct atcttcatta ctgtgtggag tcgctagtga ttggtggtga gcaagttggg
      181 attttgatta tcaatgacgg gtctcaggat cagactcagg aaatcgctga gtgtttagct
      241 agcaagtatc ctaatatcgt tagagccatc tatcaggaaa ataaatgcca tggcggtgcg
      301 gtcaatcgtg gcttggcaga ggcttctggg cgctatttta aagtagttga cagtgatgac
      361 tgggtggatc ctcgtgccta cttgaaaatt cttgaaacct tgcaggaact tgagagcaaa
      421 ggtcaagagg tggatgtctt tgtgaccaat tttgtctatg aaaaggaagg gcagtctcgt
      481 aagaagagta tgagttacga ttcagtcttg cctgttcggc agatttttgg ctgggaccag
      541 gtcggaaatt tctccaaagg ccagtatacc atgatgcact cgctgattta tcggacagat
      601 ttgttgcgtg ctagccagtt ctaactgcct gaacatactt tttatgtcga taatctcttt
      661 gtctttacgc cccttcagca ggtcaagacc atgtactatc tgcctgtcga tttctatcgt
      721 tatttgattg ggcgtgagga ccagtctgtc aatgagcaag tgatgattaa gtgcattgac
      781 cagcaactca aggtcaatcg actcttgata gaccaacttg atttgtccca agtgagtcat
      841 cccaaaatgc gagaatatct gctgaatcat attgaactca cgacggtgat ttccagtacc
      901 ctgctcaacc gatctggaac agcggagcat ctggcaaaaa aacgccaatt gtggacctat
      961 attcagcaga aaaatccaga agtctttcag gctattcgta agaccatgtt gagccgtttg
     1021 accaaacatt ctgtcttgcc agatcgcaaa ctgtccaatg tcgtctatca aatcaccaaa
     1081 tctgtttatg gatttaatta atataagtgt tttataagag ggatttaaga aaaattttaa
     1141 ctttttctta gtccttttta atttcaggag attatactag agtcatcaaa taaagaaaga
     1201 ctctaaggag aatcctatga aattcaatcc aaatcaaaga tatactcgtt ggtctattcg
     1261 ccgtctcagt gtcggtgttg cctcagttgt tgtggctagt ggcttctttg tcctagttgg
     1321 tcagccaagt tctgtacgtg ccgatgtggt caatccgacc ccaggtcaag tcttacctga
     1381 agagacatcg ggaacgaaag agggtgactt atcagaaaaa ccaggagaca ccgttctcac
     1441 tcaagcgaaa cctgagggcg ttactggaaa tacgaattca cttccgacac ctacagaaag
     1501 aactgaagtg agcgaggaaa caaactcttc tagtctggat acactttttg aaaaagatga
     1561 agaagctcaa aaaaatccag agctaacaga tgtcttaaaa gaaactgtag atacagctga
     1621 tgtggatggg acacaagcaa gtccagcaga aactactcct gaacaagtaa aaggtggagt
     1681 gaaagaaaat acaaaagaca gcatcgatgt tcctgctgct tatcttgaaa aagctgaagg
     1741 gaaaggtcct ttcactgccg gtgtaaacca agtaattcct tatgaactat tcgctggtga
     1801 tggtatgtta actcgtctat tactaaaagc ttcggataat gctccttggt ctgacaatgg
     1861 tactgctaaa aatcctgctt tacctcctct tgaaggatta acaaaaggga aatacttcta
     1921 tgaagtagac ttaaatggca atactgttgg taaacaaggt caagctttaa ttgatcaact
     1981 tcgcgctaat ggtactcaaa cttataaagc tactgttaaa gtttacggaa ataaagacgg
     2041 taaagctgac ttgactaatc tagttgctac taaaaatgta gacatcaaca tcaatggatt
     2101 agtt
//
LOCUS       DAYYYC010000097         2075 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.097, whole genome shotgun sequence.
ACCESSION   DAYYYC010000097 DAYYYC010000000
VERSION     DAYYYC010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2075
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.097"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(919..1899)
                     /locus_tag="ACHBV5_002072"
     CDS             complement(919..1899)
                     /locus_tag="ACHBV5_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HFM9967798.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDDFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKKGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT          657 a          423 c          361 g          634 t
ORIGIN      
        1 aatcccaaat aagtgaagaa ataaatcaat cagaaaactg tcgaaaaaaa ctgtcaaaag
       61 tagttcaact tgtctttttc tctgcttttt tgtcttgaat gccttaaata tcatattatt
      121 ccccttttct aagcttcaat cccttctctc tatctgttat ttcgcatagc tactactatt
      181 tttacagcaa tctatcttta aatatacata aagatagatt ctatcacttt ttataagtgt
      241 tagtaaattt attatacctc atttttaaaa cgctttcaat atagtgtaat atagtagatt
      301 ttagtttcaa aaaattcttt tatataataa tgtccttgaa agtagtttca gctgaacatt
      361 tatagtccat aaaaagaaaa cagaaactca tctgttttta tactcaatga aaatcaaaga
      421 gcaaactaag aagctagccg catgatgctc aaaacactgt tttgaggttg tagataagac
      481 tgacaaagtc agctcaaaac accgttttga ggtggcagat agaactgacg aagtcagtaa
      541 catatatacg gcaaggcgaa gctgacgtgg tttgaagaga tttttgaaaa gtattaacac
      601 ctacagacaa gcctaacgat agcaagaact accctactcg ataggtatcg gcttttgctt
      661 tctgaaaaaa attattttaa gcaatttgac aaatctagca acaaaaaatt ctataaatat
      721 aatagattga aactagaata gtacacatct acttctaaaa cattgttaga aatcgatttg
      781 actctcctga tcgatttgtc ctgttcttgt ttcattttac tatatttcca tgataaaacg
      841 catagtatca agttttctta atcccctgat actatgcgtg tttgtaattt ttaagatttt
      901 gtgcttagag tcgactcctt attttagata tttaaaagga atctcacttc cacagagcca
      961 gttgtagact tggtcattga caaatacatt catggcttcg tgagcatact caggcatgat
     1021 gcgataggtt ttatcgcagg tcagacgatt ataaatcgca aactgggtaa tgggatagca
     1081 aacatcgtcg tccaagcccg taatcatctt aacctcacct tggatacgat gggcaagatt
     1141 tttgacatcg atataggcaa gggtcgccat gatttcctcc tctgtttcat ggaaggggtc
     1201 gtgaaacttg aaataacgga aaagttcgtc gtaagcctcg ctagtattac caatctcaat
     1261 cacccgtctg aagtctgaca agaagggata aatggcaact gttttctgaa ttcgaggatt
     1321 gagcgctgct gcaactagag ctagagcccc tccttgtgag gcaccatagc tagaaagacg
     1381 cttctcatca acctgagaca gactagcaac aatttcgacc aactggtaaa tatccagata
     1441 aacatcctta taaaagaggt ggtcccgacc ttccacagca ccacggataa tatgcccctt
     1501 cacggtattt cctaaaggag aacgcaagcc gtcttgtgag taacctgact ggccccgcac
     1561 atccatggaa acaacaccgt aaccagctac ggtgaagccc agcatgtcgg cccagtccca
     1621 gccacgtccc atataaccat gaaaatggaa gattagtgga accttctcct cactctttgg
     1681 aagaacaatg cgtgcataga cctttccttt cttgcttcct tcaaatgtta actcatagca
     1741 cttgacttga ggaatgtgga aatctctttc ctccaagtgg taggatggaa gcgtggaaac
     1801 atttttcact tccccatccc agaaatcatc aaagtcttcc ggaacctcat cccttcctct
     1861 ataggtctta atttcttcta gcaaagctgg atttttcata gcatgctcct tttattttgt
     1921 aatcgttacc acaactgtag catatctatg taatcaatgc aagaaagaag ggtaaataga
     1981 aagtgaattt agattcttta cttttaggat gatgggctga aagtagtttt agaaacgaaa
     2041 aaagagcatt tcgctctctc ttctgtttat actag
//
LOCUS       DAYYYC010000098         2066 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.098, whole genome shotgun sequence.
ACCESSION   DAYYYC010000098 DAYYYC010000000
VERSION     DAYYYC010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2066
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.098"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            69..491
                     /locus_tag="ACHBV5_002073"
     CDS             69..491
                     /locus_tag="ACHBV5_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFM9967799.1"
                     /translation="MNTDYITRYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGKIEAGE
                     NHQEALKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATPFKEVQKP
                     LENFNHIAWFPIDEAIKNLKRGSHKWAIESWKKQHKIG"
     gene            656..955
                     /locus_tag="ACHBV5_002074"
     CDS             656..955
                     /locus_tag="ACHBV5_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFM9967800.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1064..>2066)
                     /locus_tag="ACHBV5_002075"
     CDS             complement(1064..>2066)
                     /locus_tag="ACHBV5_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFM9967801.1"
                     /translation="ILLNWLAQYRKNGYTIVEKTKGRVPESGECHPKKVKRTPIEGGK
                     RERRKTEIVQELMTEFSLVLLLKSIKLARSTYYYHLKQLDKTDKDQELKAEIQSIFIE
                     HKGNYAYRRIYLELRNRGYLVNHKRVQGLMKVLNLQAKMRQKRKYSSHKGDVGKKAEN
                     LIQGQFEGSKTMGKCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAYNLSTSPNLEQV
                     QTMLEQAFTEKHYENTILHSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSQDNGMMES
                     FFGILKSEMFYGYEKTFKSLNQLEQAIVDYIDYYNNKRIKVKLKGLSLVQYRTKSFG"
BASE COUNT          643 a          401 c          354 g          668 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagt gaatacagac tatattactc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gaaaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact cctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tcaaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaatcacg taagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgttataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcaactag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1021 tagcaagagt tttgtactga ccccaaaaag ttagacaaat aatttatccg aaggatttag
     1081 ttctgtattg cacaaggcta agtcctttta gttttacctt aattcgttta ttgttgtagt
     1141 aatcaatata gtctacaata gcttgttcca attgattaag tgatttaaat gttttctcat
     1201 agccataaaa catttccgat ttcagaatcc caaagaagga ctccatcata ccgttgtctt
     1261 ggctgtttcc cttacgtgac atggatgctt gaattccctt accctcaaga aactgatgat
     1321 aagaatcgtg ttgatattgc cagccttggt cactatggag aatcgtattc tcgtagtgct
     1381 tctctgtgaa tgcctgttcc aacattgttt gtacttgttc taagttgggt gaagttgaaa
     1441 gattataggc gataatttcg ctattaaagc catctaaaac tggtgataag taaagctttt
     1501 gagtacttgc tggaatggca aattctgtca catctgtata gcactttccc attgttttag
     1561 agccttcaaa ttggccttga atgagattct ctgccttctt gccaacgtct cctttatgag
     1621 aagaatattt tcgtttctgt cgcattttag cttgtaaatt gagtactttc atcaagcctt
     1681 gaactctttt atgatttacc agataaccac gatttcttag ttctaaataa atccgacgat
     1741 aagcataatt tcccttgtgt tcgataaaaa tggattgaat ttcagcttta agctcttggt
     1801 ccttatctgt tttgtctagc tgtttcaagt gatagtagta ggtcgaacga gctagtttaa
     1861 tggattttag aagaagaact aacgaaaact cagtcattaa ttcttgaaca atttctgtct
     1921 ttcttctttc tctttttcct ccttcaatcg gagttctctt aactttttta ggatggcatt
     1981 ctccgctctc aggtactctc ccttttgttt tctcaacaat agtatacccg tttttcctgt
     2041 attgtgctag ccagttaaga agtatc
//
LOCUS       DAYYYC010000099         2002 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.099, whole genome shotgun sequence.
ACCESSION   DAYYYC010000099 DAYYYC010000000
VERSION     DAYYYC010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.099"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..1673
                     /locus_tag="ACHBV5_002076"
     CDS             <1..1673
                     /locus_tag="ACHBV5_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFM9967802.1"
                     /translation="KIYSDSEKQQYLLKDNIILRKGYALKVTTYNPGKTDMLEGNGVY
                     SKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLMSALDGFNIIRYQVFTFK
                     MNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEAIKEDGSMLFIDTKPVNL
                     SMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNESVVDNYLIYGDLHIDN
                     TRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQTGYSDLNAKAVGVHYQ
                     FLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFDGEIQEQHIYVNGKEYTS
                     FDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSELKPHRVTVTIQNGKEMS
                     STIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYVINLSKDTFIKPVFKKIE
                     EKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDHSQKSDSTKDVTATVLDK
                     NNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLGLKKKNQD"
BASE COUNT          792 a          245 c          386 g          579 t
ORIGIN      
        1 gtaaaatcta ttctgattca gaaaaacaac aatatctgtt aaaggataac atcattctaa
       61 gaaaaggcta tgcactaaaa gtgactacct ataatcctgg aaaaacggat atgttagaag
      121 ggaatggagt ctatagcaag gaagatatag caaaaataca aaaggccaat cctaatctaa
      181 gagtcctttc agaaacaaca atttatgctg atagtagaaa tgttgaagat ggaagaagta
      241 cccaagctgt attaatgtcg gctttggacg gctttaacat tataaggtat caagtgttta
      301 catttaaaat gaacgataaa ggggaagcta tcgataaaga cggaaatctt gtgacagatt
      361 cttctaaact tgtattattt ggtaaggatg ataaagaata cactggagag gataagtcca
      421 atgtagaagc tataaaagaa gatggctcca tgttatttat tgataccaaa ccagtaaacc
      481 tttcaatgga taagaactac tttaatccat ctaaatctaa taaaatttat gtacgaaatc
      541 cagaatttta tttaagaggt aagatttctg ataagggtgg ttttaactgg gaattgagag
      601 ttaatgaatc ggttgtagat aattatttaa tctacggaga tttacacatt gataacacta
      661 gagattttaa tattaagttg aatgttaaag acggtgacat catggactgg ggaatgaaag
      721 actataaagc aaacggattt ccagataagg taacagatat ggatggaaat gtttatcttc
      781 aaactggcta tagcgatttg aatgctaaag cagttggagt ccactatcag tttttatatg
      841 ataatgttaa acccgaagta aacattgatc ctaagggaaa tactagtatc gaatatgctg
      901 atggaaaatc tgtagtcttt aacatcaatg ataaaagaaa taatggattc gatggtgaga
      961 ttcaagaaca acatatttat gtaaatggaa aagaatatac atcatttgat gatattaaac
     1021 aaataacaga caagacacta aacattaaga ttgttgtaaa agattttgca agaaatacaa
     1081 ccgtaaaaga attcatttta aataaagata cgggagaggt aagtgaatta aaacctcata
     1141 gggtaactgt gaccattcaa aatggaaaag aaatgagttc aacgatagtg tcggaagaag
     1201 attttatttt acctgtttat aagggtgaat tagaaaaagg ataccaattt gatggttggg
     1261 aaatttctgg tttcgaaggt aaaaaagacg ctggctatgt tattaatcta tcaaaagata
     1321 cctttataaa acctgtattc aagaaaatag aggagaaaaa ggaggaagaa aataaaccta
     1381 cttttgatgt atcgaaaaag aaagataacc cacaagtaaa ccatagtcaa ttaaatgaaa
     1441 gtcacagaaa agaggattta caaagagaag atcattcaca aaaatctgat tcaactaagg
     1501 atgttacagc tacagttctt gataaaaaca atatcagtag taaatcaact actaacaatc
     1561 ctaataagtt gccaaaaact ggaacagcaa gcggagccca gacactatta gctgccggaa
     1621 taatgtttat agtaggaatt tttcttggat tgaagaaaaa aaatcaagat taagataaaa
     1681 gctatagaaa aaaatggttt atgtactgag attagatagt gaggtgatga catagttttg
     1741 tgaaaacagc catttataac tcaattattt agtttacttc actattgata ctatttggag
     1801 ttattaatgg acttagttta gataactaat gaattgattg aaagggttag tattgacaat
     1861 attggtcata ttgattagaa aatagagtct atcaaaattt aaaggctaat agaggtgatg
     1921 agacaatttc ggctctttgt caactgtagt gggttgaagt cagctaagct cgagaaagga
     1981 caaattttgt cctttctttt tt
//
LOCUS       DAYYYC010000100         1807 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.100, whole genome shotgun sequence.
ACCESSION   DAYYYC010000100 DAYYYC010000000
VERSION     DAYYYC010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1807
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.100"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..1320
                     /locus_tag="ACHBV5_002077"
     CDS             <1..1320
                     /locus_tag="ACHBV5_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM9967803.1"
                     /translation="ILDDISLSIAEGECVLFTGKSGSGKSSLINSINGLAVRYDNAKT
                     KGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLELLFYLENIGLAREEMD
                     RRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKIIVMDESSSNLDIKSI
                     SVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLKKTYTRSEFLKLDKNE
                     LNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLKDISFKLGKIYGIIGS
                     NGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVMQDVNHQLFTDEVFNE
                     LRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAIASVMCKNSPFVFFDE
                     PSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADEIFEL"
BASE COUNT          691 a          202 c          319 g          595 t
ORIGIN      
        1 atattagatg atatatcact atccatagcc gagggagagt gcgtgctatt tacaggaaaa
       61 agtggaagtg gtaagtcatc tttaataaat tcaatcaatg gactagctgt aaggtatgat
      121 aacgcaaaga caaagggcga aataattatt gatggtaaga atataaaaaa tttggaactt
      181 tatcaaatct caatgcttgt ttcaactgtt tttcaaaatc ctaagacata tttttttaat
      241 gtcaatacga cattagaatt attattttat ttggaaaata tcggtcttgc aagagaagag
      301 atggacaggc gtttgaagga tatgcttgag atattcccga taaaaaatct tttgaacaga
      361 aatatattta atctatccgg cggtgaaaaa caaattcttt gcattgcagc ttcttatata
      421 gcaggtacaa agattatagt tatggatgag tcttcatcga atttagatat taaaagcata
      481 agtgttttgg caaagatgct aaagatatta aaagagaaag gcataagcat aattgttgca
      541 gagcatagaa tttattattt gatggacata gttgaccgtg tatttttaat agataaagga
      601 aagcttaaaa aaacttatac tagaagtgaa tttttaaagc tagataaaaa tgaattaaat
      661 gctttaagtt taagagataa agaattaagt aaattaaaag ttccttattt aaaagaaggt
      721 ggagagtatc agataaaaaa tcttagctac aaatttactg atgatgagtg tttaagctta
      781 aaagatattt cgttcaagct tgggaaaatt tatggcataa taggatccaa cggacgagga
      841 aaatcaacgc ttttaagatg tttaataggt cttgagaaaa aatcaaaaga agaaatttat
      901 tttaagggag agaagctatc taaaaaagaa agactcaaaa actcttcact tgttatgcaa
      961 gatgtaaatc atcaattatt cacagatgaa gtattcaacg agcttagatt aggagtaaag
     1021 aattttgatg aagaaaaggc gaaaatcatt ttaaaagatt taggcctgga cgaatttatt
     1081 gaaaggcatc cgatgagttt atcaggaggg caaaagcaaa ggcttgcaat agcatctgtt
     1141 atgtgcaaga attctccatt tgtctttttt gacgaacctt caagtggtat ggattattcc
     1201 aatatgataa aaatatctga actgattaat aagtataaaa ccatggataa aataattttt
     1261 attgtttccc atgatataga atttttaaat gaagtggcag atgaaatttt tgaattgtaa
     1321 aatagagtct gttaaacatg tctatagaac tggtaaattg tctaaaaatt taaaagatac
     1381 taacacatat tgatatttat tagaaaatta acttcaggat ttttacagta tttataaact
     1441 ttataatatg tatttatagt attaataatt tccatatctt tagggaaatt atttatttac
     1501 ttaccataat taaagagatg agagataaat atcggcagtc ttcggactgc ctttattttt
     1561 ttacttaatt taatgcagta aatcatacga ttgaaaggaa tctgcgttat atgatataat
     1621 taggtagtta atctatacat ttagaaaggt aaaatataga attggagaat gatatgggat
     1681 tttcatataa taaattgtaa ccgcccaata acgaagtata ttgaaaaatc tccagattag
     1741 tgaactcacg gatagttcct aatctggaga tttcttattt gcacttttct tgtacaactt
     1801 tagtcca
//
LOCUS       DAYYYC010000101         1772 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.101, whole genome shotgun sequence.
ACCESSION   DAYYYC010000101 DAYYYC010000000
VERSION     DAYYYC010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1772
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.101"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..1257
                     /locus_tag="ACHBV5_002078"
     CDS             <1..1257
                     /locus_tag="ACHBV5_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967804.1"
                     /translation="VLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYR
                     FLCSPIITDDFLNTKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIK
                     LCLEILNSIFFKKKIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFM
                     MEPNRADLTLQKTDFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVI
                     IFVVRSLIKLDQMGLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEY
                     CLLDNSLTLKNDWNYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGE
                     GKKEYEMFFQWLNFFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKG
                     LSYYLMKFLLKSFSNEYLKTTDEVNR"
     gene            1254..>1772
                     /locus_tag="ACHBV5_002079"
     CDS             1254..>1772
                     /locus_tag="ACHBV5_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFM9967805.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALF"
BASE COUNT          618 a          175 c          299 g          680 t
ORIGIN      
        1 gtattaaaca attcttttaa ttttacgagt aaagaattta atgatttaat taataacgaa
       61 aattatttat tcgaatatgc atgtagaatt agagaggaat ggagaaaaaa atgctttaat
      121 cattcttatc gttttctatg ctcacctata attacagatg attttcttaa cacgaagaca
      181 ttgagaagta gccaaattga atataaatat gagcgatatt tatcgaaaag ttcgataggc
      241 gatagagcgg ttgatggctt tgtttccttc aatactttaa cagctaatgg tatgtctgct
      301 attaaactat gtcttgagat attaaactct attttcttca agaagaagat tgatttatta
      361 tattcaaccg gatattatga aacaagattt ttattaaata atcttgctaa atcaggtatt
      421 agttgctatg aggtaagtaa ttgtgaattg gataaagata aattttataa tgtattcatg
      481 atggaaccca atcgagccga tttaacatta caaaaaactg atttcaagat agtagaatat
      541 tttgttaagt ataaaaataa ttcaataaaa gtcgttattt tagatatttc atatcaaggt
      601 tctaatttta aattagtaga atttttagag aaatttaaat ttgcgaatgt aattattttt
      661 gtggtacgat ctttgataaa attagatcaa atgggattag aattgacaaa tgggggaata
      721 atagaagtgt ttattcctaa tcatttgaga aagttgaaaa attttattga agaggaattc
      781 aataaattta gaaattctca cggagctaat ctaagcctct atgaatactg tttgcttgat
      841 aattctttaa ctttaaaaaa tgattggaac tattctgatt tagttatgaa atttacgagt
      901 aatttttatg ctgatataaa agacttgttc atggaaaatt ctgatattga aatcatccat
      961 gaagagggag taccttttgt atttttagat ttaataggtg aaggtaaaaa agaatatgaa
     1021 atgttttttc aatggttaaa cttcttttac aaacagcttg gaatcacatt gtatgctaga
     1081 aatagttttg ggtttcggaa tctaacagta gagtattttg gaattattgg gacagaaaga
     1141 tatatattta agatttgtcc aggtgtttat aaagggttaa gttattattt gatgaaattt
     1201 ttattaaaat ctttttcaaa tgaatattta aaaactactg atgaggttaa tagatgaaaa
     1261 atttgataaa gttgctaata attagattga ttgttaactt agcagacagt gtattttata
     1321 tagtagcatt gtggcacgtt agcaataatt attcttcgag catgttctta ggaatattta
     1381 ttgcagtaaa ttatctaccg gatttgttac taatcttttt tggaccagtt attgacagag
     1441 taaatccgca aaaaattctt ataatatcaa ttttggttca attagcagtg gctgtaatat
     1501 ttttattatt attaaaccaa atatcatttt gggtgataat gagtctagtg tttatttcag
     1561 taatggctag ctccataagt tacgtgatag aagatgtgtt gattcctcaa gtggtagaat
     1621 atgataagat tgtatttgca aattctcttt ttagtatttc gtataaagta ttagattcta
     1681 tttttaattc attcgcatca tttttacagg tggcagtagg atttatttta ttggttaaga
     1741 tagatatagg catattttta cttgctctat tt
//
LOCUS       DAYYYC010000102         1765 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.102, whole genome shotgun sequence.
ACCESSION   DAYYYC010000102 DAYYYC010000000
VERSION     DAYYYC010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.102"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..513
                     /locus_tag="ACHBV5_002080"
     CDS             <1..513
                     /locus_tag="ACHBV5_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HFM9967806.1"
                     /translation="IIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSDHEWM
                     LTDIKNFLTKHKAWVIDGNYSWCCYQERMQEADQIIFLNFSPLTCLFRTFKRYLKYRG
                     KVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRELDQF
                     LDKKRKSYNS"
     gene            complement(536..1246)
                     /gene="deoD"
                     /locus_tag="ACHBV5_002081"
     CDS             complement(536..1246)
                     /gene="deoD"
                     /locus_tag="ACHBV5_002081"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFM9967807.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
BASE COUNT          546 a          385 c          323 g          511 t
ORIGIN      
        1 attatcggat attctggttc tggtaagtca actctagcag aaaagttatc taactactac
       61 tccattccaa aactgcacat ggacacactc caatttcaac ctggttggca agacagtgac
      121 cacgaatgga tgttaaccga tataaaaaac tttctcacca agcataaagc ttgggtcatc
      181 gatggtaatt attcttggtg ctgctaccaa gaacgaatgc aagaagctga ccaaatcatc
      241 tttctcaatt tttcgccatt gacctgtctc tttagaacct ttaagcgtta tcttaaatac
      301 cgtggaaaag tcagagaaag tatggcggca gattgccctg aacgctttga ctgggagttt
      361 atcagatgga ttctttggga tgggcgtagc aaaactcaaa aagaaaatta ccaaaaactt
      421 tgccaagaat attcacataa agtcactatt cttcgaaatc agagagagct agatcaattt
      481 ctggataaga aaaggaagtc ctacaattca taaagggctt cctttttggc tataattatt
      541 ctgcaatcaa ggtttccaaa ccaaccttca tcatatcagt gaaggtattt tgacgttctt
      601 ctgcagttgt gtcttcgtct ggattgacca agctatcaga gatggtcatg atagctagcg
      661 catcaacatg gtattgggca gcaagatagt aaagagctgc tgcttccatt tccacagcct
      721 tgactcccca tttaccaagc tcgatattct tttcaaagta atttgagtaa aagacatcag
      781 atgacaaaac gttcccaacg tgagtagtca taccaagttt tttggcgata tggtaggctt
      841 tatcaagcaa atcaaagcta gcaatttgtg gaaaatcgta ctgtggccag tcattacgaa
      901 cgatgtttga gttggttgca gccgcctgcg ccaaaactaa ttcacgaaca tgaacctctt
      961 cattcaaaga acctgcagtt cccacacgaa tcaatttctt cacaccgtag tctacgatta
     1021 actcacgcgc ataaatcgaa atagatggca ttcccatccc agttcccatg acagatacac
     1081 agtgaccctt gtaagtacca gtgtaaccaa acatgttacg cacttcgtta aaacaaacag
     1141 catcatcaag gaaattctcc gcaataaact tagcacgaag aggatcccca ggaagaagaa
     1201 ttttatcagc aatttcaccc tgctgagcag caatatggat agacataatt tatgatacaa
     1261 agagcgagaa gaaaacgact gaaaattagg aacctgacga gaaatcctga tttttcagtc
     1321 agattatcta ttttccgagt tttccgctcg tgttcaaatc aaaacacacg ctctaccttt
     1381 ctttatttta tattttatat tgagaaagat accaaaccca tcaaaaagcg aagggaaaat
     1441 aggagttggg cgcagtgagc gatgctcgct agaccaacta tctttttccc actgctttta
     1501 gggtggggtc aattcctttc tttcttaatt ttgatttaga ggagagtcgc ccgtattcag
     1561 ttcagcgaat acagtttacc catcctttcg tttttatttt tagaaaagtt ttctactcgt
     1621 gttcaaatta gaacacgcgc tctacctttc tgtttatact cttcgaaaat ctcttcaaac
     1681 cacgtcaacg tcgccttgga ttatatatgt gactgacttc gtcagtctta tctacaacct
     1741 caaagcagtg ctttgagcaa cctgc
//
LOCUS       DAYYYC010000103         1729 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.103, whole genome shotgun sequence.
ACCESSION   DAYYYC010000103 DAYYYC010000000
VERSION     DAYYYC010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1729
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.103"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            506..>1729
                     /locus_tag="ACHBV5_002082"
     CDS             506..>1729
                     /locus_tag="ACHBV5_002082"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFM9967808.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFATKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDVY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRA"
BASE COUNT          517 a          304 c          373 g          535 t
ORIGIN      
        1 gctatatcta ttataacatg gtttaataaa ttctttgagc ttttttcttt ttaaatattg
       61 attgtttcta aaagttctag taatattgct atttctcatt tttccaaata tgttattcaa
      121 cttattagct acgtctctat tcatatttgg gtataaaaca aaaaatcaat tctaacagtt
      181 ttatatcaga ataataaata aaaaagcgat attctagact gtatcaatcc ttttccatta
      241 taggagcaac agagtgggag tagtcatcta aggactaatt tatatatttt tacgagtcag
      301 tatcttggga tactggtttt tactttttta gactttttga ctacttgtta aaactggggt
      361 aattttcgac tgtttaatag ttattatgca aagtctaaaa gattagaatt gtcaaaacaa
      421 tccgtctagg cttgatttta tcctttattt actataaaat gagaaggaaa aatgtcaaac
      481 ttttatattg caaataggag aaatcatgac aaaaacatta aaacgtcctg aggttttatc
      541 acctgcaggg actttagaga agctaaaggt agctgttcag tatggagcag atgctgtctt
      601 tatcggtggt caggcctatg gtcttcgtag ccgtgcggga aactttactt tcgaacagat
      661 ggaagaaggc gtgcagtttg cgaccaagta tggtgccaag gtctatgtag cggctaatat
      721 ggttatgcac gaaggaaatg aagctggtgc tggtgagtgg ttccgtaaac tgcgtgatat
      781 cgggattgca gcagttatcg tatctgaccc agccttgatt atgattgcag cgactgaagc
      841 accaggcctt gaaatccacc tttctaccca agccagtgcc actaactatg aaacccttga
      901 gttctggaaa gagctaggct tgactcgtgt cgttttagcg cgtgaggttt caatggaaga
      961 attagctgaa atccgcaaac gtacagatgt tgaaattgaa gcctttgtcc atggagctat
     1021 gtgtatttca tactctggac gttgtactct ttcaaaccac atgagtatgc gtgatgccaa
     1081 ccgtggtgga tgttctcagt catgccgttg gaaatacgac ctttacgata tgccatttgg
     1141 gaaagaacgt aagagtttgc agggtgagat tccagaagaa ttttcaatgt cagccgttga
     1201 catgtctatg attgaccata ttccagatat gattgaaaat ggtgtggaca gtctaaaaat
     1261 cgaaggacgt atgaagtcta ttcactacgt atcaacagta accaactgct acaaggcggc
     1321 tgtggatgtc tatcttgaaa gtcctgaaaa gtttgaagct atcaaacaag acttggtgga
     1381 cgagatgtgg aaggttgccc aacgtgaatt ggcaacaggt ttctactacg gtataccatc
     1441 tgaaaatgag cagttgtttg gtgctcgccg taaaattcct gagtacaagt ttgtcgctga
     1501 agtggtttct tatgatgatg cggcacaaac agcaaccatt cgtcaacgaa acgtcattaa
     1561 cgaaggggac caagttgagt tttatggtcc aggtttccgt cattttgaaa cctatattga
     1621 agatttgcat gatgccaaag gcaataaaat cgaccgcgct ccaaatccaa tggaactatt
     1681 gactattaaa gtcccacaac ccgttcaatc aggagacatg gttcgtgca
//
LOCUS       DAYYYC010000104         1484 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.104, whole genome shotgun sequence.
ACCESSION   DAYYYC010000104 DAYYYC010000000
VERSION     DAYYYC010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1484
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.104"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            1..913
                     /locus_tag="ACHBV5_002083"
                     /pseudo
     CDS             1..913
                     /locus_tag="ACHBV5_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612110.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(936..1286)
                     /gene="tnpB"
                     /locus_tag="ACHBV5_002084"
     CDS             complement(936..1286)
                     /gene="tnpB"
                     /locus_tag="ACHBV5_002084"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFM9967809.1"
                     /translation="MIIQLSDLGQVHLVCSKIDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPNTEKDVKALTPEQVDWLMTGFS
                     ITPKINPSESRDFY"
BASE COUNT          463 a          270 c          309 g          442 t
ORIGIN      
        1 ataaactgta atcaaacaac gatttggcga aatgtaaaaa aatatgagga gttcggactc
       61 gactctctcc ttcaagaaac acgtggtggt cgtaaccatg catatatgac ggttgaggaa
      121 gagaaagcct ttcttgcccg tcatttgaag gctgcagagg caggagaatt tgttacaatt
      181 gatgccttat ttcaggctta taaaaaggag ttaggtcgtt cctacacacg tgatgccttc
      241 tatcaactgt tgaagcgcca tggttggcga aatattatgc cacgtccaga acatcctaag
      301 aaagcagacg ctcaaaccat tgtcgcgtct aaaaataaaa tctcaattca agaagaaaag
      361 aaagcgcttt aaaaccagta gacgttttca taaggtttgc ttgatgtacc aagatgaggc
      421 tggtttcggt agaatcagta aactgggatc ttgttggtct ccaataggag taggtctaca
      481 tgtccatagt cactatatac gagaatttcg ctattgttat ggagctgttg atgcctatac
      541 aggcgaatca tttttcttaa tagctggtgg atgtaatact gagtggatga acgccttttt
      601 agaagagctt tcacaagctt atccagatga ttatctttta ctcgttatgg acaatgctgt
      661 atggcataaa tcaagtacct taaagattcc gactaatatt ggctttgcat ttattcctcc
      721 atacacacca gagatgaacc ccattgaaca attgttgaaa gagattcgta aacgtggatt
      781 taagaataaa gcctttcgaa ctttggaaga tgtcatgaat caactccaag atgttataca
      841 aggactggag aaggaggtga taaagtccat cgttaatcgg agatggaata gaatgctttt
      901 tgaaagcaga tgagtataaa aagaaagtcc tcatttcaat agaaatcacg actttctgat
      961 ggatttattt ttggagtgat agaaaagccc gtcataagcc agtctacttg ttcaggtgtg
     1021 agagctttga catccttttc tgtattgggc caagtcagtc tgccgttctc aaagcgttta
     1081 tatagtagcc aaaatccttg accatcccag taaagggctt taaagcggtc tttacgtcca
     1141 ccacaaaaga gaaagacttg accggagaaa ggatccaatt caaagtgggt tttaactaca
     1201 taggctaatg agtctattcc ctgcctcata tctatcttgc tacaaacaag gtgaacttga
     1261 cctaaatcac ttagttgaat tatcatagta caataccttt cctccgataa ttatttttta
     1321 tctagtatac tggaagttgg ggaattagga tagatacctt gttatgacgc gcttacgtaa
     1381 cttgtaacta gctgcctagt ttgatctttg cttcttcatt gattagcagt agatttcaaa
     1441 atgataaaaa cgcataatag tgggtgtaga atgaactgcc ttcc
//
LOCUS       DAYYYC010000105         1455 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.105, whole genome shotgun sequence.
ACCESSION   DAYYYC010000105 DAYYYC010000000
VERSION     DAYYYC010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.105"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..559
                     /locus_tag="ACHBV5_002085"
     CDS             <1..559
                     /locus_tag="ACHBV5_002085"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFM9967810.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPKTVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="ACHBV5_002086"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="ACHBV5_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HFM9967811.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT          506 a          208 c          265 g          476 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccaa
      181 aacagttcat agttaccaga aagaaagatt actaagagat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgg
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcggggg ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg ccgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtga
//
LOCUS       DAYYYC010000106         1314 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.106, whole genome shotgun sequence.
ACCESSION   DAYYYC010000106 DAYYYC010000000
VERSION     DAYYYC010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1314
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.106"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..1080
                     /locus_tag="ACHBV5_002087"
     CDS             <1..1080
                     /locus_tag="ACHBV5_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HFM9967812.1"
                     /translation="EKKLPNESLVTILHNEVENIADSLVINNIYDEYPIWSIPVNFKG
                     SKWCLEQTGNDMYRGRAGILLFMYYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFG
                     LTGDIGYFIVLSIIEDYDTNTLACLNYIKSVLTELEKTDFASVSNKSDYINGLLPLIN
                     TLVRYYRRGIEKERVLRLVLSLGDTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYK
                     VTRLKKYKELILQLVPREKIKIHSLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHG
                     SMAIINFYIDYMKEMDTSMELESLLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGI
                     AYTFLRYIALNQNDKKIVIPSLLEI"
BASE COUNT          474 a          158 c          230 g          452 t
ORIGIN      
        1 gaaaaaaaac tcccaaatga aagtttagtt actattctgc ataatgaagt agaaaatatt
       61 gcagactctt tggttattaa taatatttat gacgaatatc caatttggag tatacctgtt
      121 aattttaaag gttctaaatg gtgtcttgaa caaacgggta atgatatgta taggggtaga
      181 gctggaatat tactgtttat gtactatgta aaattattga aagataaatc atcatatact
      241 caactgtaca ataaaatgtt atctgcaatt ccgccatctg tttctttatc taagaccaca
      301 tttggtttaa ctggggatat aggatatttc attgttctat ccattataga ggattacgat
      361 acaaatactc tcgcatgctt aaattatata aagagtgttt taactgagct tgaaaagact
      421 gattttgcaa gtgtttcaaa caagtctgac tatattaatg gtcttctacc tttaattaat
      481 acactggtaa gatattatag gagaggaata gagaaggaac gtgttctaag gctagtatta
      541 agtttaggtg atacgctata taatgatgta agcgagagag ataatagtaa ttttggatat
      601 agttttggcc atggactatc aggtgtaatt tttacattaa aaaatattta taaagtgaca
      661 agacttaaaa aatataaaga attaatttta caactagttc ctagggagaa aatcaaaatt
      721 cattctttga agtggtgtag tggagaattt gggacattag ttaatcatcc ccaaagtgtt
      781 ccagagggaa ttgtagctag tttagataat gatacatttt gccatggaag tatggccata
      841 ataaattttt acatcgacta catgaaagaa atggatacta gtatggaatt ggagtcttta
      901 ttgtgtagtg ttgtaatgaa taaatcaaaa gaaggagagt atcgtatcgt ccaaacaagc
      961 aatttcccag atttttcttt gtatacaggt gtgactggta ttgcttatac ttttttaagg
     1021 tatatcgcac tgaatcagaa tgacaaaaag atagttatcc cctcattact tgaaatctag
     1081 cttaatttat agttttgttt ctaaaataga ggtgtccact cattaagcaa tataaaaata
     1141 ccaagattga ctagtttaat atgtaattct ataaaatatt tttaatagtg tagcttttca
     1201 ttgagataat aatataataa agaaaagttc tattctaatt gctaaacggc ttgaggtata
     1261 tgctactgtt atagaaatga ttttaaacta aaatcaaaat tactccaaaa atag
//
LOCUS       DAYYYC010000107         1215 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.107, whole genome shotgun sequence.
ACCESSION   DAYYYC010000107 DAYYYC010000000
VERSION     DAYYYC010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.107"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..1169
                     /locus_tag="ACHBV5_002088"
     CDS             <1..1169
                     /locus_tag="ACHBV5_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ISNCY-like element IS1202 family transposase"
                     /protein_id="HFM9967813.1"
                     /translation="ETYKPNVLHFCELLAEEEGIKLSDTTVRKILYKKNILSPKSHRK
                     TKKRVRKQAKLNLNQPLDNPILPTAKDFLEDPKKVHPSRPRKKFAGELIQMDASPHAW
                     FGPETTNLHLAIDDASGNILGAYFDKQETLNAYYHVLEQILANHGIPLQMKTDKRTVF
                     TYQASNSKKMEDDTYTQFGYACHQLGILLETTSIPQAKGRVERLNQTLQSRLPIELER
                     NKIHTLEEANTFLLSYIQTFNEQFGNKTKLSVFEEAPNPSERNLILARLAERVVDSGH
                     HIRFQNRCYIPTEQGKEVYFIRKTKALVLKAFDGDIYLNIADKIYHTKELLDHELYSK
                     NFEQEPEQKKERRKYIPPQTHPWKLTSFKQYLHKNKKDYEEFTSEEIHSPQLQV"
BASE COUNT          438 a          285 c          201 g          291 t
ORIGIN      
        1 atgaaacata taaaccaaat gtccttcatt tctgtgaatt actagctgaa gaagagggaa
       61 ttaagctctc tgatacaact gttagaaaaa tactctataa gaaaaacatc ctttctccta
      121 agtctcacag aaagacaaag aagagagtaa gaaaacaagc taaactgaac ctgaatcaac
      181 ccctagacaa tccaatctta ccgacggcta aagacttcct ggaagaccct aaaaaggtac
      241 atcctagtag acccagaaag aaatttgctg gagaactcat tcaaatggat gccagccctc
      301 atgcctggtt tggaccagaa accaccaact tacacttagc cattgatgat gcttctggca
      361 atatcctagg ggcttatttt gacaaacaag agaccttgaa tgcctactac catgtcctcg
      421 aacaaatctt agccaatcac ggcattcccc ttcaaatgaa aactgataag agaacggtct
      481 ttacctatca agcatccaac tctaagaaaa tggaggacga cacctataca caatttggat
      541 acgcctgtca ccaactaggg attctccttg agaccacctc tatccctcaa gctaaaggga
      601 gggtcgaaag actcaatcag acactacaat cacgcctgcc tatcgaactg gaacgaaaca
      661 agattcatac attggaagaa gccaatactt tccttctttc ctacatccaa acctttaatg
      721 aacagtttgg aaataagaca aaactctctg tttttgagga ggctcctaac ccctctgaac
      781 ggaatctcat tctagctaga ctggcggaga gagtcgtcga tagtggacac catatccgat
      841 tccaaaaccg ttgctatatt cctaccgaac aaggaaaaga agtctatttc atcagaaaga
      901 cgaaagcatt agttctaaaa gcatttgatg gtgacatcta cctcaatatc gctgacaaaa
      961 tctatcacac aaaggagcta ctagatcatg aactctattc gaaaaacttt gaacaagaac
     1021 cagaacaaaa aaaagaaaga cgcaagtata tccctccaca aacccatccg tggaaactca
     1081 catctttcaa acaatacctt cataaaaaca aaaaggatta tgaagagttt actagtgagg
     1141 agattcattc tcctcaacta caagtataat ctatttttcg ctaaatggga agcttttcct
     1201 taaaggaagt cactc
//
LOCUS       DAYYYC010000108         1170 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.108, whole genome shotgun sequence.
ACCESSION   DAYYYC010000108 DAYYYC010000000
VERSION     DAYYYC010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1170
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.108"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            231..>1170
                     /locus_tag="ACHBV5_002089"
     CDS             231..>1170
                     /locus_tag="ACHBV5_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HFM9967814.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEEGPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEF"
BASE COUNT          411 a          204 c          244 g          311 t
ORIGIN      
        1 taccttagtc aagaattaga tgtttcacta tgtttgagta agttgatgat ttcatttgat
       61 aacaggtttg aaactgttag gctaggtggc caaggctaat catagccttg gtttagctga
      121 aaaaacaggt tcaagggttc ctgttgtcaa atgaaatgtg atttaaggta taagaaaaca
      181 cctctgtgct atacttgttg ttcaccacaa acacaaggaa aggcacagag atgcaagaac
      241 attatacccc aaaagggaaa catttgacaa tagataaccg tcgcttgatt gagcggtgga
      301 agaatgaaaa taagtccaat cgtgaaattg caggcttgtt aggaaaggcg cctcaaacga
      361 ttcataatga agtcaaaaga ggtacaactt tacaacaagt gagaaaaggg ctatacaaaa
      421 aggtctattc tgccgattac gcacaaactg tttaccaatt caatcgaaaa cggtcggtga
      481 aaaagttaat tttaacaaag gaaatcagag agaagatctt acactatcat aagcaaaaat
      541 tttcgcctga aatgatggtt aacaagaagc aagtgaaagt tggtatttca accatctact
      601 actggtttca taatggtcat ttaggattga cgaaggccga catgctttat cccagaaaaa
      661 ggaaaggtgt caagaagcaa gctagtccga actttaagcc ggcaggtaaa tctatcgaag
      721 aaggtcctga cgttattaat cttcgcttgg aaaatggtca ttatgaaatt gataccgtcc
      781 tactgactaa gataaaaaat tattgcctgt tagtcttaac cgaccggcgg agcagacacc
      841 aaattataag gttaattcca aataaaactg ctgaatctgt caatcaggcg cttacgttac
      901 tattagggga gcatcgtatt ctgtccatta ctgcagataa tggttcggag ttcaaacgat
      961 tgtctgaggt atttcctgag gaacatatct actacgcaca tgcttactct tcatgggaga
     1021 gaggttcaaa tgaaaatcat aatcgattaa ttcggagatg gttacctaaa ggaaccaaga
     1081 aaacgactcc gaaagaagta gcttttatcg aaaattggat taacaactac cctaaaaaat
     1141 gcttggacta caagtcgcca agtgaatttc
//
LOCUS       DAYYYC010000109         1133 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.109, whole genome shotgun sequence.
ACCESSION   DAYYYC010000109 DAYYYC010000000
VERSION     DAYYYC010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1133
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.109"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            45..392
                     /locus_tag="ACHBV5_002090"
     CDS             45..392
                     /locus_tag="ACHBV5_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFM9967815.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEIEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(509..1133)
                     /locus_tag="ACHBV5_002091"
                     /pseudo
     CDS             complement(509..1133)
                     /locus_tag="ACHBV5_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          338 a          210 c          213 g          372 t
ORIGIN      
        1 tttaaaagat cggagcaatc cggtcttttt atggaggaga gtaaatgaat ttaaatcaat
       61 tagatattat cgtttcaaat gttccccaag tctgtgctga cttggagcat atcttggata
      121 aaaaggcaga ttatgctgat gatggttttg ctcagtttac gattggtagt cactgcctta
      181 tgttgtcaca aaatcatttg gttcctttgg aaaactttca gtcaggaatc attattcata
      241 tcgagattga ggatgtagac cagaactaca aacggttgaa cgagcttggt ataaaggttt
      301 tacacggacc aactgtaacc gattggggaa cagagtcctt attagttcaa ggacctgctg
      361 gtctagtgct tgatttttat cgtatgaaat aggtcgcgta gtcatttgac gttaacctta
      421 gctattttta aaatagaaat tgagaatatg aactattgaa agatcggagc aatccggtct
      481 ttttatataa agaaattgca tataatactc atctgctttc aaaaagcatt ctagtccatc
      541 tccgattaac gatggacttt atcacctcct tctccaatcc ttgtatgaca tcttggagtt
      601 gattcatgac atcttccaaa gttcgaaagg ctttattctt aaatccacgt ttacgaatct
      661 ctttccacac ttgttcaatg gggttcatct ctggtgtgta tggaggaata aatgcaaagc
      721 caatattagt cggaatcttt aaggtacttg atttatgcca tatagcattg tccataacga
      781 gtaaaaaata atcatatgga taagcttgtg aaagctcttc taaaaagacg ttcatccact
      841 cagtattaca tccaccagct cttaagaaaa atgattcgcc tgtataggca tcaacagctc
      901 cataacaata gcgaaattct cgtatatagt gactatggat atgtggacct actcctattg
      961 gagaccaaca agatcccagt ttactgattc taccgaaacc agcctcatct tggtacatca
     1021 agcgaacctt acgaaaacgt ctactggttt taaatcgctt tcttttcttc ttgaattgag
     1081 attttatttt tagacgcgac aatggtttga gcgtctgctt tcttaggatg ttc
//
LOCUS       DAYYYC010000110         1057 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.110, whole genome shotgun sequence.
ACCESSION   DAYYYC010000110 DAYYYC010000000
VERSION     DAYYYC010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1057
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.110"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(1..599)
                     /locus_tag="ACHBV5_002092"
                     /pseudo
     CDS             complement(1..599)
                     /locus_tag="ACHBV5_002092"
                     /inference="COORDINATES: protein motif:HMM:NF015038.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            603..886
                     /locus_tag="ACHBV5_002093"
                     /pseudo
     CDS             603..886
                     /locus_tag="ACHBV5_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612110.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            883..1057
                     /locus_tag="ACHBV5_002094"
                     /pseudo
     CDS             883..1057
                     /locus_tag="ACHBV5_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238800.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          329 a          231 c          197 g          300 t
ORIGIN      
        1 actgactgac ggcggcacca agcaaagaag tcttccatta ggggctggag atgttcttga
       61 cgtttctgta gtcgttcatc agctggcaaa gcctcccagt ctctttccaa ggaaaataac
      121 tgatcacaat aagctaaacc tttagctcct aaggatgatt tatctgcttg cttgggggtc
      181 gcttcaaaaa atttccttct cacatgcgcc caacatccaa caagttcagc ttcttccagt
      241 tgacgataag cttctagcag ttcgcagttt accaagctta gcgtcgcctt gctcctaaac
      301 cttggactgc tatcgcatag gcagaactag aggactaaag tcctaagtta ctgccgcaac
      361 atatcacaat gaacatagcc agaataatct cctaggaatt cttgtactac cgaaccactc
      421 cgactctgat catgatggta cagcgtgatt gcttgattct caactttccc agacaaaaag
      481 gtccaatagt aggtcagatg gctatgactc tctagaaccc gataagaagt ttcatccgca
      541 tgaagtaagg gctgagtcaa tagtctctct cgcaagaggt tataaagggg ctttaggaat
      601 aggagctttc acaagcttat ccagatgatt atcttttact cgttatggac aatgctatat
      661 ggcataaatc aagtacctta aagattccga ctaatattgg ttttgcattt attcctccat
      721 acacaccaga gatgaacccc attgaacaag tgtggaaaga gattcgtaaa cgtggattta
      781 tagtaaaatg aaataataac aggacaaatc attcaggaca gtcaaatcga tttctaacaa
      841 tgttttagaa gcagaggtgt actattctag tttcaatcta ctatagataa acttttgagc
      901 tattcagaag acttgaaaca ccactataat ctctatcaac tcttgctttt tcactttcag
      961 aataaggagc ctgacaaatt tttcggactc attgaggaca atctgaatca ggttcatcct
     1021 ctaaaacctt cctcaaagat aaagagaaga ttgtcaa
//
LOCUS       DAYYYC010000111         1012 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.111, whole genome shotgun sequence.
ACCESSION   DAYYYC010000111 DAYYYC010000000
VERSION     DAYYYC010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1012
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.111"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            231..706
                     /locus_tag="ACHBV5_002095"
                     /pseudo
     CDS             231..706
                     /locus_tag="ACHBV5_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            744..>1012
                     /locus_tag="ACHBV5_002096"
     CDS             744..>1012
                     /locus_tag="ACHBV5_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFM9967816.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFD"
BASE COUNT          342 a          163 c          196 g          311 t
ORIGIN      
        1 gtgttttgag taacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtatta
       61 gaacagaaaa atgcttggag tatttgtttg tgtgtttatt tttatataac aaactataaa
      121 cacaacaaaa atataaaaaa agagacaaaa aagaacagaa agtaattaac aacgatttca
      181 tatagtgtta tacttatagc ataaagttaa tggaaagaag ggaaaacctt atggtattag
      241 attatttctt tgacaaaaac cttgtgtttt gcttagaagc ggataatcaa gaataactct
      301 ttgatcaggt agcaagcttg ttggaggaac gagaaattgt aactccaact tatcgtgaag
      361 ctttgatcac gcgtgaaaag tcatttccaa ctggtttaga tatggaattt ctaggaaagg
      421 acttgcaaat gtaatgattc ctcacacaga tattgttcat aatctagctg agaaagtggt
      481 ggttgttcga ttagagaaac cggtgacttt ccataatatg attgcgccag gtaaggaagt
      541 agaagtatcc ttgctcttct ttatcatcaa taattcaagt tcaagtcaaa cgaacattct
      601 tgctcagttg atggactttt tcacaggaaa tggacatctt gaagacctat caaaaatttc
      661 cgaaccagaa aaactttatg cttatataga tgaagcaatc gcttaatctt gtctattaaa
      721 aaataaaatc ggaggaagtc tatatgatta aaattcttgc tgcctgcggt gcaggtgtta
      781 actcaagtca ccaaattaaa agtgctctag aagaagaact ttcaaaccgt ggttacgatg
      841 ttcactgtga tgcagttatg gtgaaagatg taaacgaaga ccttatgaaa ggttacgata
      901 tctttacacc aatcgctgca acagaccttg gttttgaacc aggtatccca gttatcgaag
      961 ctgggccaat cttattccgt atcccagcaa tgagcgttcc agtatttgac aa
//
LOCUS       DAYYYC010000112         1011 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.112, whole genome shotgun sequence.
ACCESSION   DAYYYC010000112 DAYYYC010000000
VERSION     DAYYYC010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1011
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.112"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            54..169
                     /gene="rrf"
                     /locus_tag="ACHBV5_002097"
     rRNA            54..169
                     /gene="rrf"
                     /locus_tag="ACHBV5_002097"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            175..248
                     /locus_tag="ACHBV5_002098"
     tRNA            175..248
                     /locus_tag="ACHBV5_002098"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:209..211,aa:Asn,seq:gtt)
     gene            356..1011
                     /locus_tag="ACHBV5_002099"
                     /pseudo
     CDS             356..1011
                     /locus_tag="ACHBV5_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
BASE COUNT          334 a          173 c          204 g          300 t
ORIGIN      
        1 attgttttct tggtttgaat agatattcaa ttttgagtag gtattactca gagttaagtg
       61 acgatagcct aggagataca cctgtaccca tgccgaacac agaagttaag ccctagaacg
      121 ccggaagtag ttgggggttg ccccctgtga gatagggaag tcgcttagct ttaatccgcc
      181 atagctcagt tggtagtagc gcatgactgt taatcatgat gtcgtaggtt cgagtcctac
      241 tggcggagta attgagttaa gaggtttaga cctctttttt gttatgtaat aataatctat
      301 tttgtgttat agtaaaatga accaaaaata gtacacaatg tggtataatc tttttatggc
      361 atattcaata gattttcgta aaaaagttct ctcttattgt gagcgaacag gtagtataac
      421 agaagcgtca cacgttttcc aaatctcacg taataccatt tatggctggt taaagctaaa
      481 agagaaaaca ggagagctaa accaccaagt aaaaggaaca aaaccaagaa aggttgatag
      541 agatagactt aaaaactatc ttactgacaa tccagacgct tatttgactg aaatagcttc
      601 tgaatttggc tgtcatccaa ctaccatcca ctatgcgctc aaagctatgg gctacactcg
      661 aaaaaaagaa ccacacctac tatgaacaag acccagaaaa agtagcctta tttcttaaaa
      721 attttaatag tttaaagcac ctagcacctg tttatattga tgaaacagga ttcgatactt
      781 atttttatcg agaatatggt cgctcattaa aaggtcagtt aataagaggt aaagtatctg
      841 gaagaagata tcagaggatt tctttggttg caggtctaac aaatggtgag ttaatcgctc
      901 caatgactta cgaagagatg gtgacgagcg acttttttga agcttggttt cagaagtttc
      961 tcttaccaac attaaccaca ccatcggtta ttattatgga taatgcaaga t
//
LOCUS       DAYYYC010000113         1001 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.113, whole genome shotgun sequence.
ACCESSION   DAYYYC010000113 DAYYYC010000000
VERSION     DAYYYC010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1001
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.113"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            77..229
                     /gene="rpmG"
                     /locus_tag="ACHBV5_002100"
     CDS             77..229
                     /gene="rpmG"
                     /locus_tag="ACHBV5_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFM9967817.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            239..415
                     /gene="secE"
                     /locus_tag="ACHBV5_002101"
     CDS             239..415
                     /gene="secE"
                     /locus_tag="ACHBV5_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFM9967818.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            470..>1001
                     /gene="nusG"
                     /locus_tag="ACHBV5_002102"
     CDS             470..>1001
                     /gene="nusG"
                     /locus_tag="ACHBV5_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFM9967819.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT          347 a          147 c          205 g          302 t
ORIGIN      
        1 acaatagtca atctatttcg ctaagatgct tgtcaaagcc tagctttctt gttataatgg
       61 ataagatgga ggcgttatgg cactaaaaaa agcaagccta gcttgtgcgg tttgtggttc
      121 gagaaactat tcaatcaaga tcagcggaaa ccccaagcct acacgactag aagtaaataa
      181 attttgtaag cattgtggca agtacactac acacagagaa acgagatagg agagagcgat
      241 gcgttttatt ggagatattt ttagacttct taaagacaca acgtggccaa ctcgcaagga
      301 aagctggaga gattttcgtt ctatcatgga atacacagct ttctttgtag taattattta
      361 catttttgac cagttgattg tttcaggttt gattcgattt attaacattt tttagaagat
      421 tagtggagtt aattacacta gaaatcttct atttatgaaa ggaaatatca tggatagttt
      481 tgataaaggg tggtttgttt tacaaactta ttctggttat gaaaataagg tgaaagaaaa
      541 tctattacaa cgtgcacaaa cctacaatat gttggataat attctacgcg ttgaaattcc
      601 aacacaaaca gtgcaagttg aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt
      661 tccaggttat gttcttgtag aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa
      721 cacaccaaat gttacaggat ttgtcggatc acacgggaac agatcaaaac caactccatt
      781 attggaacaa gaaattcgtg acattttggt atctatggga caaactgttc aagaatttga
      841 tttcgatgtt gagattggtc aaactgtacg tattattgat ggtgcttttg cagactacac
      901 tggtaagatt acagaaattg ataataacaa agtgaaaatg attatctcta tgtttggtaa
      961 tgacacagtt gcagaagtaa acctaaacca aatcgcagaa t
//
LOCUS       DAYYYC010000114          824 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.114, whole genome shotgun sequence.
ACCESSION   DAYYYC010000114 DAYYYC010000000
VERSION     DAYYYC010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..824
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.114"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            1..707
                     /locus_tag="ACHBV5_002103"
                     /pseudo
     CDS             1..707
                     /locus_tag="ACHBV5_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433508.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          271 a          174 c          131 g          248 t
ORIGIN      
        1 atcaaccaaa agattgctca aaagttaatt gaaaagattt ctatgaccga cattgatcat
       61 cagttgtcta tttcaacttc aactgtcatt cgcaagatca atgattttca ctttgagcat
      121 gatttttcgc gtcttcctga gattatgtcc taggacgttg aaacagtctg gggagtgact
      181 gtttcaatcg ggagatagag atgagcttta ttgctcagga ctttgataag ctcaatatca
      241 taactgttct tgagagcaga acacaagcca tcatccgaaa tcccatgaat acaaggctat
      301 caagcgctac tggagctcat tcaacaagat agtcagaaac tgagtgataa acgattttat
      361 cgccctactt ttcgtatgca cttgactaat aaagaaattc tagataaact tttgagctat
      421 tcgaagactt gaaacaccac tataatctct atcagctata atctctatca gctcttgctt
      481 ttccacctct ttttcagact ctgtttaaaa ccttcctcaa agataaagag aaaatcgtca
      541 acgcccttca attaccttat tccaacgcca aactggaagc caccaataat ctcatcaaac
      601 ttatcaagca caatgccttt ggttttagga actttgaaaa cttcaaaaaa gaaaggacga
      661 aatttgtcct ttctagatct tcgctttctt caacccacta cagttgacaa agaaccgaaa
      721 aatgtctcgc ctctaatata gtcaattgaa acaagaacaa gagaaaagag cctcgtaaaa
      781 ggtattgcaa cttggtaata cctttttgag gttctttttg atat
//
LOCUS       DAYYYC010000115          806 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.115, whole genome shotgun sequence.
ACCESSION   DAYYYC010000115 DAYYYC010000000
VERSION     DAYYYC010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.115"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..>806
                     /gene="phtD"
                     /locus_tag="ACHBV5_002104"
     CDS             <1..>806
                     /gene="phtD"
                     /locus_tag="ACHBV5_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HFM9967820.1"
                     /translation="YTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHS
                     HWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPL
                     DRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYV
                     EHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEP
                     THPESDEKENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSV"
BASE COUNT          285 a          160 c          180 g          181 t
ORIGIN      
        1 tacactgatg atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt
       61 tatatctttg atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat
      121 atgacccata gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc
      181 caggcttatg ctaaagagaa aggtttgacc cctccttcga cagaccatca ggattcagga
      241 aatactgagg caaaaggagc agaagctatc tacaaccgcg tgaaagcagc taagaaggtg
      301 ccacttgatc gtatgcctta caatcttcaa tatactgtag aagtcaaaaa cggtagttta
      361 atcatacctc attatgacca ttaccataac atcaaatttg agtggtttga cgaaggcctt
      421 tatgaggcac ctaaggggta tactcttgag gatcttttgg cgactgtcaa gtactatgtc
      481 gaacatccaa acgaacgtcc gcattcagat aatggttttg gtaacgctag cgaccatgtt
      541 caaagaaaca aaaatggtca agctgatacc aatcaaacgg aaaaaccaaa cgaggagaaa
      601 cctcagacag aaaaacctga ggaagataag gaacatgatg aagtaagtga gccaactcac
      661 cctgaatctg atgaaaaaga gaatcacgct ggtttaaatc cttcagcaga taatctttat
      721 aaaccaagca ctgatacgga agagacagag gaagaagctg aagatactac agatgaggct
      781 gaaattcctc aagtagagca ttctgt
//
LOCUS       DAYYYC010000116          794 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.116, whole genome shotgun sequence.
ACCESSION   DAYYYC010000116 DAYYYC010000000
VERSION     DAYYYC010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..794
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.116"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            19..>794
                     /locus_tag="ACHBV5_002105"
     CDS             19..>794
                     /locus_tag="ACHBV5_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HFM9967821.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKS"
BASE COUNT          251 a          166 c          131 g          246 t
ORIGIN      
        1 atcattagaa agattcatat ggaacaatta cattttatca caaaactgct cgatattaaa
       61 gacccaaaca tcaagattct agatatcatc aatatggata cccacaaaga aattatcgct
      121 aagctggatt atgaggctcc atcttgccct gattgtggaa gtctaatgaa gaaatatgac
      181 tttcaaaaac cgtctaagat cccttacctc gaaacaactg gtatgccttc tagaattctc
      241 cttagaaaac gccgtttcaa gtgctatcac tgttcaaaaa tgatggttgc tgagactccc
      301 ctggtaaaga aaaatcacca aatccctcgt atcatcaacc aaaaaattgc tcaaaagtta
      361 attgaaaaaa tttctatgac tgatattgcc catcagctgg ccatttcaac ttcaactgtc
      421 attcgcaagc tcaatgactt tcactttgag catgattttt ctcggcttcc aaagattatg
      481 tcttgggatg agtatgcctt cactaaggga aagatgagtt tcattgcgca agattttgat
      541 aatcttaata ttatcactgt tcttgaaggc agaacacaag ctgtcatccg aaatcacttt
      601 cttcgctacg atagagccgt tcgttgtcaa gtgaaaatca ttacgatgga tatgtttagt
      661 ccttactatg acttggctaa acagcttttt ccgtgtgcta aaatcgttct agatcgtttc
      721 catattatcc aacatctcag ccgtgccatg agtcgttttc gtgttcaaat tatgaatcag
      781 tttgaacgaa aatc
//
LOCUS       DAYYYC010000117          783 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.117, whole genome shotgun sequence.
ACCESSION   DAYYYC010000117 DAYYYC010000000
VERSION     DAYYYC010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.117"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            1..614
                     /locus_tag="ACHBV5_002106"
                     /pseudo
     CDS             1..614
                     /locus_tag="ACHBV5_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          281 a          139 c          136 g          227 t
ORIGIN      
        1 taaatcacca agtaaaagga acaaaaccaa gaaaagttga tagagataga cttaaaaact
       61 atcttactga caatccagac gcttatttga ctgaaatagc ttctgaattt ggctgtcatc
      121 caactaccat ccactatgcg ctcaaagcta tgggctacac tcgaaaaaaa agaaccacac
      181 ctactatgaa caagagccag aaaaagtagc cttatttctt aagaatttta atagtttaaa
      241 gcacctagca cctgtttaga ttgatgaaac aggattcgat acttattttt atcgagaata
      301 tggtcgctca ttaaaaggtc agttaataag aggcaaagta tctggaagaa gatatcagag
      361 aatttctttg gttgcaggtc taacaaatga atggtgagtt aatcgctcca atgacttacg
      421 aagagacgat gacgagcgac ttttttgaag cttggtttca gaagtttctc ttaccaacat
      481 taaccacacc atcagttatt attatggata atgcaagatt ccatagaatg ggtaagttag
      541 aactcttgtg tgaagagttt gggtataaac ttttacctct tcctccctac tcacctgagt
      601 acaatcctat tgaggctcta taatatttgt agtgggtaaa tcccctatgg atattatgga
      661 gcctattttt gtgtagaaaa aaagtcccat aagatctata atgaaaagcg atcaaacaac
      721 tcattagaaa gattcatatg gaacaattac attttatcac aaaattacta gacattaaag
      781 acc
//
LOCUS       DAYYYC010000118          706 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.118, whole genome shotgun sequence.
ACCESSION   DAYYYC010000118 DAYYYC010000000
VERSION     DAYYYC010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..706
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.118"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(74..147)
                     /locus_tag="ACHBV5_002107"
     tRNA            complement(74..147)
                     /locus_tag="ACHBV5_002107"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="ACHBV5_002108"
     tRNA            complement(157..242)
                     /locus_tag="ACHBV5_002108"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="ACHBV5_002109"
     tRNA            complement(250..321)
                     /locus_tag="ACHBV5_002109"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="ACHBV5_002110"
     tRNA            complement(344..416)
                     /locus_tag="ACHBV5_002110"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="ACHBV5_002111"
     tRNA            complement(435..516)
                     /locus_tag="ACHBV5_002111"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="ACHBV5_002112"
     tRNA            complement(522..594)
                     /locus_tag="ACHBV5_002112"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="ACHBV5_002113"
     tRNA            complement(619..691)
                     /locus_tag="ACHBV5_002113"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          182 a          206 c          155 g          163 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ctttgggagt taacgg
//
LOCUS       DAYYYC010000119          684 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.119, whole genome shotgun sequence.
ACCESSION   DAYYYC010000119 DAYYYC010000000
VERSION     DAYYYC010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..684
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.119"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(1..83)
                     /locus_tag="ACHBV5_002114"
                     /pseudo
     CDS             complement(1..83)
                     /locus_tag="ACHBV5_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(318..629)
                     /locus_tag="ACHBV5_002115"
     CDS             complement(318..629)
                     /locus_tag="ACHBV5_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HFM9967822.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCSFCFSRFNPGCQNHKERYF
                     K"
BASE COUNT          227 a          127 c          106 g          224 t
ORIGIN      
        1 tctttcccaa atggcatatc gtaaaggtcg tatttccaac ggcatgactg agaacatcca
       61 ccacggttgg catcacgcat actctagacg caattctaat cttttagact ttgcataata
      121 actgttaaac agttgaaaat taacccagtt ttaacaagta gtcaaaatac cagataaagg
      181 aaaaaagtct ttaaaatctt aaaaacgcat agtatcaggt attgaacaat cttgatatta
      241 tgcgttttat tgtgggaaga tttacttcat tttctcttgg aattgagttt tctcctactt
      301 caaaactaga tgatttgcta tttaaaatag cgttccttat gattttggca acctggatta
      361 aagcgagaaa aacaaaagga gcaacttaaa ctttctttat attgcttata tgttagtagt
      421 tttagacaaa caccacataa aataggctta tcctgtatca aagataaggg atacggctca
      481 aaagggtgat tttctaatga atcatgacac cgataacaag catagtactt tttacaatca
      541 tagcattgta aagcaataat atccaacttg ctatggtaat gaatgcatct tgtttgctta
      601 tccactaaga aaccctgtgc ctctatcatt tccttttcct ttcttaagca cgaactgtga
      661 cgctggttcc atcttcctta taaa
//
LOCUS       DAYYYC010000120          614 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.120, whole genome shotgun sequence.
ACCESSION   DAYYYC010000120 DAYYYC010000000
VERSION     DAYYYC010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..614
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.120"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(31..510)
                     /locus_tag="ACHBV5_002116"
     CDS             complement(31..510)
                     /locus_tag="ACHBV5_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFM9967823.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGELSHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          163 a          142 c           81 g          228 t
ORIGIN      
        1 taattttttt catttttttt gcatgacttc ctagtgggta cggatagtaa actccttaaa
       61 cacaatgcgt aagtctctta atactctttg acgccctcga aatcgttcat tgcttaagac
      121 acgttctagt tcttcttgtt tctctttact ttgtttgttt ctataatctc ttagtgtttc
      181 atgaaagaga taataatcat ctagccagag acccccctca cttatacgat gactgagctc
      241 acccacttct tcatagggtt ctttatcgta tctacgcttc tgactttcct gcttacggat
      301 atagtctaaa attcgatttc gaaacttggt tttgaaatat ttccttaaac gtggaatatc
      361 gtctaccagt ccttcttctc tactaatcaa ttcatgtaag cagagcatgc cttcttggtc
      421 ccaatccgat aattcccata aatgaaggta atattcattt ctacacttat acacagtccc
      481 ttggacttct tcatacaatt ctttaatcat aattttcccc tttctagata cagtctaaca
      541 gattagaaaa cacatttgtt ccattttctc cattctgttc cctttagctc ctaaactgca
      601 caaaaaagag aggc
//
LOCUS       DAYYYC010000121          600 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.121, whole genome shotgun sequence.
ACCESSION   DAYYYC010000121 DAYYYC010000000
VERSION     DAYYYC010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..600
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.121"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(<1..>600)
                     /locus_tag="ACHBV5_002117"
     CDS             complement(<1..>600)
                     /locus_tag="ACHBV5_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM9967824.1"
                     /translation="DIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYAFTKGK
                     MSFIAQDFNNLNIITVLKGRTQAVIRNHFLKYDRAVRCRVKIITMDMFSPYYDLARQL
                     FPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDSRKLSD
                     KRFYRPTFRMHLTNKEILDKLLSYSQDLKHHYQLYQLLLF"
BASE COUNT          196 a          102 c          126 g          176 t
ORIGIN      
        1 aaacagcaag agttgataga gctgatagtg gtgtttcaag tcttgtgaat agctcaaaag
       61 cttgtctaaa atctctttat tggttaagtg catacgaaaa gtaggacgat aaaatcgctt
      121 atcactcagt ttacggctat cctgttgtat gagcttccag tagcgcttga tagccttgta
      181 ttcatgggat tttcgatgaa actgattcat gatttgaaca cgcacacgac tcatagcacg
      241 gctaagatgt tgtacaatgt gaaagcgatc caacacgatt ttagcacacg ggaaaagttg
      301 tctagctaaa tcatagtaag gactaaacat atccatagta atgattttga cgcgacatcg
      361 gacggctcta tcatatttaa gaaagtgatt tcggatgaca gcttgtgttc ttcccttaag
      421 aacagtgatg atattgagat tgttaaaatc ttgcgcaatg aagctcatct ttccttttgt
      481 aaaagcatac tcatcccaag acataatctc aggaagacaa gaaaaatcat gtttaaagtg
      541 aaagtcattg agcttacgaa taacagttga agttgagatg gaaagctgat gggcaatatc
//
LOCUS       DAYYYC010000122          572 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.122, whole genome shotgun sequence.
ACCESSION   DAYYYC010000122 DAYYYC010000000
VERSION     DAYYYC010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..572
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.122"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            77..439
                     /locus_tag="ACHBV5_002118"
     CDS             77..439
                     /locus_tag="ACHBV5_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HFM9967825.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFGNE"
BASE COUNT          182 a           71 c          105 g          214 t
ORIGIN      
        1 aacctcaaaa cagtgttttg agcaacctga ggctagtttc ctagtttgct ctttggtttt
       61 cattgagtat aacagattgt tagaagttgg tttaaatttc ctaatcagtt tgttcacatt
      121 taccttcgat atattatatc ccatagttaa ggttggtcat acagatgatt atagtcatgg
      181 agccgtaaaa cttagtgttt ctttagttga caaagatgcc atgaaaaaaa tatctgtaac
      241 tgtaatagga tattttgaaa taaatataga tgaaaatatc accgatattc tatacgtaaa
      301 tggtactgct attctttatc attatttacg ttctattgtt tcaatagttt cggcaattga
      361 tagcagtgaa gcaatgttgc tacctaccat taatgtttta gagttactag ataaatctca
      421 accttttggg aatgagtaga tggattgaat aaaattttat taagagtgga tgatttatct
      481 gtagattatt attggacagt tagtcttgaa gtagtctaag aattaggtta taatcagtag
      541 aatccttgct aataatgagg aggttagttt at
//
LOCUS       DAYYYC010000123          550 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.123, whole genome shotgun sequence.
ACCESSION   DAYYYC010000123 DAYYYC010000000
VERSION     DAYYYC010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.123"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..>550
                     /gene="cbpA"
                     /locus_tag="ACHBV5_002119"
     CDS             <1..>550
                     /gene="cbpA"
                     /locus_tag="ACHBV5_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline-binding protein CbpA"
                     /protein_id="HFM9967826.1"
                     /translation="AEATRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAP
                     QPEKPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQPS
                     TPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNA
                     NGSMATGWLQNNGSWYYLNANGS"
BASE COUNT          222 a          128 c          111 g           89 t
ORIGIN      
        1 aagctgaggc tacaaggtta gaaaaaatca agacagatcg taaaaaagca gaagaagaag
       61 ctaaacgaaa agcagcagaa gaagataaag ttaaagaaaa accagctgaa caaccacaac
      121 cagcgccggc tcctcaacca gaaaaaccag ctccagctcc aaaaccagag aatccagctg
      181 aacaaccaaa agcagaaaaa ccagctgatc aacaagctga agaagactat gctcgtagat
      241 cagaagaaga atataatcgc ttgactcaac agcaaccgcc aaaaactgaa aaaccagcac
      301 aaccatctac tccaaaaaca ggctggaaac aagaaaacgg tatgtggtac ttctacaata
      361 ctgatggttc aatggcgaca ggatggctcc aaaacaatgg ctcatggtac tacctcaaca
      421 gcaatggcgc tatggcgaca ggatggctcc aaaacaatgg ttcatggtac tatctaaacg
      481 ctaatggttc aatggcaaca ggatggctcc aaaacaatgg ttcatggtac tacctcaacg
      541 ctaatggttc
//
LOCUS       DAYYYC010000124          539 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.124, whole genome shotgun sequence.
ACCESSION   DAYYYC010000124 DAYYYC010000000
VERSION     DAYYYC010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..539
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.124"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            1..539
                     /locus_tag="ACHBV5_002120"
                     /pseudo
     CDS             1..539
                     /locus_tag="ACHBV5_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          200 a          108 c           92 g          139 t
ORIGIN      
        1 tcttcttcta aaagccatta aactagctcg ttcgacctac tactatcact tgaaacagct
       61 agacaaaaca gataaggacc aagagcttaa agctgaaatt caatccatct ttatcgaaca
      121 caagggaaat tatgcttatc gtcggattta tttagaacta agaaatcgtg gttatctggt
      181 aaatcataaa agagttcaac acttgatgaa gtactcaatt tacaagctaa aacgcgacag
      241 aaacgaaaat attcttctca taaaggagac gttggcaaga aagcagagaa tctcattcaa
      301 ggccaatttg aaggctctaa aacaatggaa cagtgctaca cagatgtgac tgaatttgcc
      361 attccagtaa gtactcaaaa gctttactta tcaccagttt tagatggctt taatagcgaa
      421 attatcgcct ataatctttc aacttcaccc aacttagaac aagtacaaac aatgttggaa
      481 caggcattca aagagaagca ctacgagaat acgattctcc atagtgacca aggctggca
//
LOCUS       DAYYYC010000125          443 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.125, whole genome shotgun sequence.
ACCESSION   DAYYYC010000125 DAYYYC010000000
VERSION     DAYYYC010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.125"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            5..92
                     /locus_tag="ACHBV5_002121"
     tRNA            5..92
                     /locus_tag="ACHBV5_002121"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Ser,seq:gct)
     gene            complement(297..>443)
                     /locus_tag="ACHBV5_002122"
     CDS             complement(297..>443)
                     /locus_tag="ACHBV5_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFM9967827.1"
                     /translation="AKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFV
                     LSRA"
BASE COUNT          121 a           68 c           94 g          160 t
ORIGIN      
        1 aattggagaa ttactcaaga ggctgaagag gacggtttgc taaatcgtta ggtcgggtaa
       61 ctggcgcaag ggttcgaatc ccttattctc cgttttaatg agagtttgta actctctttt
      121 ttatttttag agacaataaa gcttcagatc cgtaaaactt aattgaatta ctaatctgaa
      181 gttattttta ggctctttgt caactgtagt gggttgaagt cagctaagct cgagaaagga
      241 caaatttcgt cctttctttt ttggctcttt gtcaactgta gtgggttgaa aaaaagctaa
      301 gctcgagaaa ggacaaattt tgtcctttct tttttgatgt tcaaagcgat aaaaatcctt
      361 tttttgaagt tttcaaagtt ccgaaatcca aaggcgtttc gtttgataag tttgatgaga
      421 ttatttgtcg cttccagttt ggc
//
LOCUS       DAYYYC010000126          437 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.126, whole genome shotgun sequence.
ACCESSION   DAYYYC010000126 DAYYYC010000000
VERSION     DAYYYC010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.126"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..>437
                     /locus_tag="ACHBV5_002123"
     CDS             <1..>437
                     /locus_tag="ACHBV5_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM9967828.1"
                     /translation="RYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLK
                     HHYQIYQLLLFHFQNKDPEKFFGLIEDTLKQVHPIFQTVFKTFLKNKEKIVNALQLPY
                     SNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERT"
BASE COUNT          159 a           93 c           61 g          124 t
ORIGIN      
        1 cgttactgga aactcatcca acaggatagt cgtaaattga gcgataaacg tttttatcgc
       61 cctacttttc gcatgcactt aacaaataaa gaaattcttg acaagatttt aagctattca
      121 gaagacttga aacaccacta tcagatctat caactcttac tttttcactt tcagaacaaa
      181 gaccctgaga aatttttcgg actcattgag gacactctga agcaggttca tcctattttt
      241 cagactgtct ttaaaacctt tctaaagaac aaagaaaaaa tcgtcaacgc tcttcaatta
      301 ccttattcca acgcaaaatt ggaagcgacc aataatctca tcaaacttat caaacgaaac
      361 gcctttggat ttcggaactt tgaaaacttc aaaaaaagga tttttatcgc tctgaacatc
      421 aaaaaagaaa ggacgaa
//
LOCUS       DAYYYC010000127          435 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.127, whole genome shotgun sequence.
ACCESSION   DAYYYC010000127 DAYYYC010000000
VERSION     DAYYYC010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.127"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..225
                     /locus_tag="ACHBV5_002124"
     CDS             <1..225
                     /locus_tag="ACHBV5_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoU domain-containing protein"
                     /protein_id="HFM9967829.1"
                     /translation="QSGCLDMVVIQKQNEIEELSINMEKKIMNYIFEDDGNVSEVISA
                     LDIIHHLDKIAHTTQAIYKWIMYRKYGNIN"
     gene            238..>435
                     /locus_tag="ACHBV5_002125"
     CDS             238..>435
                     /locus_tag="ACHBV5_002125"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="catalyzes the formation of alpha-D-glucose
                     1-phosphate and UDP-galactose from UDP-glucose and
                     alpha-D-galactose 1-phosphate in galactose metabolism;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFM9967830.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIK"
BASE COUNT          189 a           37 c           82 g          127 t
ORIGIN      
        1 caatctggat gtttagatat ggttgttata caaaaacaga atgagataga agagcttagt
       61 ataaatatgg aaaagaaaat aatgaattac atatttgaag atgatgggaa cgtttctgaa
      121 gtaattagtg ctttagatat tattcatcac cttgataaaa ttgctcatac tacgcaagca
      181 atttataaat ggataatgta tagaaaatat gggaacataa attagaaaga aaaatatatg
      241 aaaacaatta ttgataattt tgttgataga gtaattgaat acggaatgta taatgaaatt
      301 gacaaaatat atgtgaaaaa tagagtacta gcgttaatag gtgaggaggg aattgatcgc
      361 atttccgatg aaaatgacct gaaacaaata aaagattact tagtggaaat cgccttaaaa
      421 aacggtaaaa ttaaa
//
LOCUS       DAYYYC010000128          379 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.128, whole genome shotgun sequence.
ACCESSION   DAYYYC010000128 DAYYYC010000000
VERSION     DAYYYC010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.128"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            105..>379
                     /locus_tag="ACHBV5_002126"
     CDS             105..>379
                     /locus_tag="ACHBV5_002126"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase 2C family protein"
                     /protein_id="HFM9967831.1"
                     /translation="MLVNEMEITDHRVDNLFEKGKNEIKDSIGTNSVLNKKIILQKIR
                     KLSNQPSGYWIGSLDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQN"
BASE COUNT          147 a           39 c           65 g          128 t
ORIGIN      
        1 attctagttt caatatacta tattatcgct taccaatatt tgcttttata tttgctaaac
       61 tttcagaaaa aaagttggag tatatgatgc taggtgactg cgtcatgtta gtaaacgaaa
      121 tggaaataac tgatcataga gtagataact tatttgaaaa agggaaaaat gagataaaag
      181 attcaattgg tacaaatagt gttttaaata aaaaaattat tttacaaaaa atcagaaaat
      241 tatctaatca accgagtggg tactggatag gttcgttgga tgagagattt ttagaccatg
      301 ctattattaa tcaaatagat gttactagtg aacaaattgt tttaatgagc gatggctttt
      361 atgaattcta tcaaaataa
//
LOCUS       DAYYYC010000129          379 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.129, whole genome shotgun sequence.
ACCESSION   DAYYYC010000129 DAYYYC010000000
VERSION     DAYYYC010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.129"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            20..>379
                     /locus_tag="ACHBV5_002127"
     CDS             20..>379
                     /locus_tag="ACHBV5_002127"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFM9967832.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRM"
BASE COUNT          158 a           30 c           66 g          125 t
ORIGIN      
        1 ttattagaga agagtagtca tggataggaa tatagatcaa gaattagtaa gtattataat
       61 accaacacat aataggtatg aatctctgat tagagctgtg aaaagttgtt tacatcaaag
      121 ttataaaaat atcgaagtta taattattga tgataattat agtaatgtaa atttaagaaa
      181 taaaattatc catcaatttg gctatacaaa tcatagaatt aagttaattt taagtaatga
      241 agatttaggt gcaactaatg ccagaaacat aggtataaaa aattctagag gtaagtatat
      301 atcattttta gacgatgatg atgaatatat gccagatcga attttaaagt tgatggcttg
      361 ttttaaaaag agtagaatg
//
LOCUS       DAYYYC010000130          369 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.130, whole genome shotgun sequence.
ACCESSION   DAYYYC010000130 DAYYYC010000000
VERSION     DAYYYC010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.130"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            47..>369
                     /locus_tag="ACHBV5_002128"
     CDS             47..>369
                     /locus_tag="ACHBV5_002128"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFM9967833.1"
                     /translation="MDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICH
                     LKCRDNFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNVGGLS
                     EIIEH"
BASE COUNT          122 a           42 c           78 g          127 t
ORIGIN      
        1 attttgtatt ccaaataaca aaaaaatcat ttgttatatt ggaaggttgg atccagaaaa
       61 aaggccggat agattccttg aatttgcaga aaaattattt ttagtcagag aagatgtgat
      121 ttttattatg gctggaaatg gtagtatgtg ggctgctttg aaagaaaaaa tttgccattt
      181 gaaatgtaga gataatttca ggttacttgg tgaaatctat ccagctacta tagtttacca
      241 aatatcggat ttattgtata ttccttctga tacagaagga atacctatgt gtgttttaga
      301 gtcaatgtca caaggaactc cggttttagc tagtaatgtt ggcgggttaa gtgaaattat
      361 tgaacatag
//
LOCUS       DAYYYC010000131          367 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.131, whole genome shotgun sequence.
ACCESSION   DAYYYC010000131 DAYYYC010000000
VERSION     DAYYYC010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.131"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..>367
                     /locus_tag="ACHBV5_002129"
     CDS             <1..>367
                     /locus_tag="ACHBV5_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HFM9967834.1"
                     /translation="NGTREEEKTDFVGNPLFVQMVHNIAGTSFWLCKKEVLELINGFE
                     KIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENGITGVTQKTINADEEYYNYC
                     RKYFNLLSFNERILVTKKYY"
BASE COUNT          135 a           42 c           76 g          114 t
ORIGIN      
        1 aatggtacac gagaagagga gaagaccgat tttgttggaa atcccttgtt tgttcaaatg
       61 gttcacaata tagcaggtac gtcattttgg ttgtgtaaaa aagaggtgct agaattaatt
      121 aatggttttg agaaaataga ttcacatcag gacggtgttg ttttattaaa actacttgct
      181 caaggatacc aaattgatat agtgcgagaa ttcttggtga attactacgc tcacagtaaa
      241 gaaaacggta tcactggagt gacacaaaaa acaattaatg cagatgaaga atattataat
      301 tactgtagga aatattttaa tttattgagt ttcaacgaga gaatattggt tacaaagaaa
      361 tattatt
//
LOCUS       DAYYYC010000132          343 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.132, whole genome shotgun sequence.
ACCESSION   DAYYYC010000132 DAYYYC010000000
VERSION     DAYYYC010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.132"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..>343
                     /locus_tag="ACHBV5_002130"
     CDS             <1..>343
                     /locus_tag="ACHBV5_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PhoU domain-containing protein"
                     /protein_id="HFM9967835.1"
                     /translation="ELSNNLETIWVSVLDKYEKLFEYLSNEERVELIKEDLIINESVL
                     NIDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNLQILQNNEILKK
                     IISEIKILHEV"
BASE COUNT          145 a           27 c           53 g          118 t
ORIGIN      
        1 tagaattatc aaataattta gagaccattt gggtatctgt gcttgataaa tatgagaagt
       61 tatttgaata tttatcaaat gaagaacgag tagaattgat taaagaagat ttaatcataa
      121 atgagtcagt tctaaatatt gataaaaaag gatatgagtt aatttgttta caacatcctg
      181 tttcatatga cttaagaaga attattagtg taataaaaat atcaactgac attgaacgta
      241 ttggggatag aattgttgaa attttaaaaa atctacagat tcttcaaaat aatgaaattt
      301 tgaagaaaat tatttcagaa ataaaaatac ttcatgaagt tat
//
LOCUS       DAYYYC010000133          324 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.133, whole genome shotgun sequence.
ACCESSION   DAYYYC010000133 DAYYYC010000000
VERSION     DAYYYC010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.133"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..>324
                     /locus_tag="ACHBV5_002131"
     CDS             <1..>324
                     /locus_tag="ACHBV5_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HFM9967836.1"
                     /translation="AEATKLEEIKTDRKKAEEEAKRKAEAEEDKVKDKLKRRTKRAVP
                     GEPATPDKKENGAKSSDSSVGEETLPSPSLKPEKKVAEAEKKVAEAEKKAKDQKEEDR
                     RNYPT"
BASE COUNT          147 a           57 c           77 g           43 t
ORIGIN      
        1 aagctgaggc tacaaagtta gaagaaatca agacagatcg taaaaaagca gaagaagaag
       61 ctaaacgaaa agcagaagca gaagaagata aagttaaaga taaactaaag aggcggacaa
      121 aacgagcagt tcctggagag ccagcaacac ctgataaaaa agaaaatggt gcgaagtctt
      181 cagattctag cgtaggtgaa gaaactcttc caagcccatc cctgaaacca gaaaaaaagg
      241 ttgcagaagc tgagaagaag gttgcagaag ctgagaaaaa agccaaggat caaaaagaag
      301 aagatcgccg taactaccca acca
//
LOCUS       DAYYYC010000134          288 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.134, whole genome shotgun sequence.
ACCESSION   DAYYYC010000134 DAYYYC010000000
VERSION     DAYYYC010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.134"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..123
                     /locus_tag="ACHBV5_002132"
     CDS             <1..123
                     /locus_tag="ACHBV5_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM9967837.1"
                     /translation="KASQWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGEWVN"
BASE COUNT           99 a           53 c           53 g           83 t
ORIGIN      
        1 aaagcaagcc aatggttcaa agtatcagat aaatggtact atgtcaatgg ctcaggtgcc
       61 cttgcagtca acacaactgt agatggctat ggagtcaatg ccaatggtga atgggtaaac
      121 taaacctaat ataactagtt aatactgact tcctgtaaga actctttaaa gtattcccta
      181 caaataccat atcctttcag tagataatat acccttgtag gaagtttaga ttaaaaaata
      241 actctgtaat ctctagccgg atttatagcg ctagagacta cggagttt
//
LOCUS       DAYYYC010000135          283 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.135, whole genome shotgun sequence.
ACCESSION   DAYYYC010000135 DAYYYC010000000
VERSION     DAYYYC010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.135"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            <1..>283
                     /locus_tag="ACHBV5_002133"
     CDS             <1..>283
                     /locus_tag="ACHBV5_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HFM9967838.1"
                     /translation="DKRIKRLRRISGGDTYTIIYLKLLLLSLKDEGKLYYDGVESDFI
                     KELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTEIPNLIGSETA"
BASE COUNT          121 a           41 c           52 g           69 t
ORIGIN      
        1 gacaaaagga taaaaaggtt aaggagaata tctggaggag atacctatac gataatctac
       61 ctaaaacttc tactactaag cctaaaagat gagggcaaac tctattatga cggagtagaa
      121 agtgatttta taaaagagtt agcactaacc atagatgaaa cagacgatga tgtaatggta
      181 acagtaaatt atttaatcaa tcaaggctta ttagaagttg taacagaaaa tgatgaatac
      241 tacctaactg aaataccaaa cttaatcgga tcagaaacag cct
//
LOCUS       DAYYYC010000136          276 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.136, whole genome shotgun sequence.
ACCESSION   DAYYYC010000136 DAYYYC010000000
VERSION     DAYYYC010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..276
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.136"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(80..153)
                     /locus_tag="ACHBV5_002134"
     tRNA            complement(80..153)
                     /locus_tag="ACHBV5_002134"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(117..119),aa:Ile,seq:gat)
     gene            complement(188..258)
                     /locus_tag="ACHBV5_002135"
     tRNA            complement(188..258)
                     /locus_tag="ACHBV5_002135"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(224..226),aa:Gly,seq:tcc)
BASE COUNT           88 a           71 c           61 g           56 t
ORIGIN      
        1 atagtttata cgggaacaag cccgtgtcct cttagtgaac agataatatt ccaatcccct
       61 agtaatggac taaacactat gggcacgagt ggactcgaac caccgacctc acgcttatca
      121 ggcgtgcgct ctaaccacct gagctacgcg cccaagtcaa aaacttggta caaagaacaa
      181 agttcaaagc gggtgacgag aatcgaactc gcgacaacag cttggaaggc tgtagtttta
      241 ccactaaact acacccgcta aaatgggagt taacgg
//
LOCUS       DAYYYC010000137          247 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate 1101552
            SAMN41612426-rid22607043.denovo.137, whole genome shotgun sequence.
ACCESSION   DAYYYC010000137 DAYYYC010000000
VERSION     DAYYYC010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN41612426
            Sequence Read Archive: SRR29245691
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002291340.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002291340.1
            Genome Coverage       :: 31x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 19:05:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,136
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 77 of 146
            Pseudo Genes (incomplete)         :: 66 of 146
            Pseudo Genes (internal stop)      :: 51 of 146
            Pseudo Genes (multiple problems)  :: 40 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..247
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN41612426-rid22607043.denovo.137"
                     /isolate="1101552"
                     /isolation_source="Middle ear fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="USA"
                     /lat_lon="41.743111 N 91.592041 W"
                     /collection_date="2019"
                     /collected_by="Element,JMI Labs"
     gene            complement(86..247)
                     /locus_tag="ACHBV5_002136"
                     /pseudo
     CDS             complement(86..247)
                     /locus_tag="ACHBV5_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT           76 a           45 c           39 g           87 t
ORIGIN      
        1 agtagattga aactagaata gtacacatct acttctaaaa cattgttaga attcgatttt
       61 actgtcctga tcgatttgtc ctattcttat ttcgttttac tataataacc gatggtgtgt
      121 ttaatgttgg taagagaaat ttctgaaacc atacttcaaa aaagtcgctc gtcatcgtct
      181 cttcgtaagt tattggagcg attaactcac catttgttag acctgcaacc aaagaaatcc
      241 tctgata
//
